diff --git a/Dockerfile b/Dockerfile
index 5fac848..74e068b 100755
--- a/Dockerfile
+++ b/Dockerfile
@@ -20,8 +20,8 @@ RUN apt-get update \
  && apt-get clean \
  && rm -rf /var/lib/apt/lists/*
 
-ARG RDKIT_VERSION=Release_2020_03_2
-RUN wget --quiet https://github.com/rdkit/rdkit/archive/${RDKIT_VERSION}.tar.gz \
+ARG RDKIT_VERSION=Release_2022_03_4
+RUN wget --quiet https://github.com/rdkit/rdkit/archive/refs/tags/${RDKIT_VERSION}.tar.gz \
  && tar -xzf ${RDKIT_VERSION}.tar.gz \
  && mv rdkit-${RDKIT_VERSION} rdkit \
  && rm ${RDKIT_VERSION}.tar.gz