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<!DOCTYPE html>
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<nav class="navbar navbar-expand-lg navbar-dark bg-primary fixed-top" id="sideNav">
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<span class="d-block d-lg-none">Merritt Khaipho-Burch</span>
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<img class="img-fluid img-profile rounded-circle mx-auto mb-2" src="/img/headshot.jpg" alt="">
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<div class="collapse navbar-collapse" id="navbarSupportedContent">
<ul class="navbar-nav">
<li class="nav-item">
<a class="nav-link js-scroll-trigger" href="/#about">About</a>
</li>
<li class="nav-item">
<a class="nav-link js-scroll-trigger" href="/#skills">Skills</a>
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<a class="nav-link js-scroll-trigger" href="/#projects">Projects</a>
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<a class="nav-link js-scroll-trigger" href="/#open">Open Source</a>
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<a class="nav-link js-scroll-trigger" href="/#Publications">Publications</a>
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<a class="nav-link js-scroll-trigger" href="/#experience">Experience</a>
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<a class="nav-link js-scroll-trigger" href="/#education">Education</a>
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<div class="container-fluid p-0">
<section class="resume-section p-3 p-lg-5 d-flex d-column" id="about">
<div class="my-auto">
<div class="resume-item d-flex flex-column flex-md-row">
<div class="mr-auto">
<h1 class="mb-0">Merritt
<span class="text-primary">Khaipho-Burch</span>
</h1>
<div class="subheading mb-5">Ithaca, NY ·
<a href="mailto:[email protected]">mbb26<span style="display:none">-remove-</span>[email protected]</a>
</div>
</div>
</div>
<div>
<p>I am a Ph.D. Candidate in Ed Buckler’s lab in the Section of Plant Breeding and Genetics at Cornell University. My research investigates the extent to which pleiotropy controls phenotypes within the maize genome and the role of transposable elements in regulating gene expression. I have a passion for designing and implementing models to understand the genetic basis and regulation of complex quantitative traits. In my free time I enjoy hiking, baking, and creating beadwork.</p>
<p>To see my full CV, <a href="https://github.com/merkhaiburch/personal_website/blob/main/CV_Khaipho_Burch_2023_long.pdf">click here.</a></p>
<p>Contact me at: <a href="mailto:[email protected]">[email protected]</a></p>
<h3>Socialization</h3>
<ul class="list-inline list-social-icons mb-0">
<li class="list-inline-item">
<a href="https://www.linkedin.com/in/merrittkhaiphoburch/" data-toggle="tooltip" title="LinkedIn" data-offset="0,10" rel="me">
<span class="fa-stack fa-lg">
<i class="fa fa-circle fa-stack-2x"></i>
<i class="fab fa-linkedin fa-stack-1x fa-inverse"></i>
</span>
</a>
</li>
<li class="list-inline-item">
<a href="https://github.com/merkhaiburch" data-toggle="tooltip" title="GitHub" data-offset="0,10" rel="me">
<span class="fa-stack fa-lg">
<i class="fa fa-circle fa-stack-2x"></i>
<i class="fab fa-github fa-stack-1x fa-inverse"></i>
</span>
</a>
</li>
<li class="list-inline-item">
<a href="https://twitter.com/MerKhaiBurch" data-toggle="tooltip" title="Twitter" data-offset="0,10" rel="me">
<span class="fa-stack fa-lg">
<i class="fa fa-circle fa-stack-2x"></i>
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<a href="https://scholar.google.com/citations?user=lvFMbpwAAAAJ&hl=en" data-toggle="tooltip" title="Google Scholar" data-offset="0,10" rel="me">
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</ul>
</div>
</div>
</section>
<section class="resume-section p-3 p-lg-5 d-flex flex-column" id="skills">
<div class="my-auto" id="skills-content">
<h2 class="mb-5">Skills</h2>
<div class="subheading mb-3 skills-heading">Quantitative Genetics</div>
<ul>
<li class="list-inline-item">
<i class="devicons devicons-terminal_badge"></i>
QTL Mapping
</li>
<li class="list-inline-item">
<i class="devicons devicons-terminal_badge"></i>
Association Mapping (mixed, general, matrix eQTL)
</li>
<li class="list-inline-item">
<i class="devicons devicons-terminal_badge"></i>
Genomic Prediction (SNP, expression, metabolite)
</li>
<li class="list-inline-item">
<i class="devicons devicons-terminal_badge"></i>
RNA and DNA Sequence Analysis
</li>
<li class="list-inline-item">
<i class="devicons devicons-terminal_badge"></i>
Machine Learning (random forest, gradient boosting models)
</li>
</ul>
<div class="subheading mb-3 skills-heading">Languages, Operating Systems & Tools</div>
<ul>
<li class="list-inline-item">
<i class="devicons devicons-terminal_badge"></i>
R
</li>
<li class="list-inline-item">
<i class="devicons devicons-terminal_badge"></i>
R Studio
</li>
<li class="list-inline-item">
<i class="devicons devicons-terminal_badge"></i>
bash
</li>
<li class="list-inline-item">
<i class="devicons devicons-git"></i>
git
</li>
<li class="list-inline-item">
<i class="devicons devicons-windows"></i>
windows
</li>
<li class="list-inline-item">
<i class="devicons devicons-apple"></i>
apple
</li>
<li class="list-inline-item">
<i class="devicons devicons-linux"></i>
linux
</li>
</ul>
<div class="subheading mb-3 skills-heading">Code Management</div>
<ul>
<li class="list-inline-item">
<i class="devicons devicons-github"></i>
github
</li>
<li class="list-inline-item">
<i class="devicons devicons-bitbucket"></i>
Bitbucket
</li>
</ul>
</div>
</section>
<section class="resume-section p-3 p-lg-5 d-flex flex-column" id="projects">
<div class="my-auto" id="projects-content">
<div class=" pb-2 pt-3">
<h2><a href="https://merkhaiburch.github.io/projects/creations/">Ongoing Projects</a></h2>
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</div>
<h3 class="mb-3"><a href="https://merkhaiburch.github.io/projects/creations/te_expression/">Limited contribution of transposable elements to regulatory adaptation in maize inbreds and hybrids</a></h3>
<div class="resume-item d-flex flex-column flex-md-row mb-3">
<div class="resume-content" style="width:200px;">
<img src="/img/te.png" style="max-height:150px;max-width:150px;"/>
</div>
<div class="resume-date">
<p>Transposable elements (TEs) make up ~85% of the maize genome, however, little is known of their effects on gene expression under non-stressed conditions.<p>
<p class><a href="https://merkhaiburch.github.io/projects/creations/te_expression/">Read more..</a></p>
</div>
</div>
<div><ul class="tags">
</ul>
</div>
<h3 class="mb-3"><a href="https://merkhaiburch.github.io/projects/creations/pleiotropy/">Elucidating the patterns of pleiotropy and its biological relevance in maize</a></h3>
<div class="resume-item d-flex flex-column flex-md-row mb-3">
<div class="resume-content" style="width:200px;">
<img src="/img/test_pleiotropy_2.png" style="max-height:150px;max-width:150px;"/>
</div>
<div class="resume-date">
<p>Using association mapping of common alleles in over one hundred thousand traits, we show little evidence that pleiotropy is a common phenomenon in maize.<p>
<p class><a href="https://merkhaiburch.github.io/projects/creations/pleiotropy/">Read more..</a></p>
</div>
</div>
<div><ul class="tags">
</ul>
</div>
<h3 class="mb-3"><a href="https://merkhaiburch.github.io/projects/creations/yield_project/">The perils and promise of single-gene solutions to crop yield: extraordinary claims require extraordinary evidence.</a></h3>
<div class="resume-item d-flex flex-column flex-md-row mb-3">
<div class="resume-content" style="width:200px;">
<img src="/img/yield.jpg" style="max-height:150px;max-width:150px;"/>
</div>
<div class="resume-date">
<p>I lead a large collaborative effort to write a policy/perspective piece on the common reasons how crop productivity studies can be inaccurately measured and suggest testing guidelines moving forward.<p>
<p class><a href="https://merkhaiburch.github.io/projects/creations/yield_project/">Read more..</a></p>
</div>
</div>
<div><ul class="tags">
</ul>
</div>
</div>
</section>
<section class="resume-section p-3 p-lg-5 d-flex flex-column" id="open">
<div class="my-auto" id="projects-content">
<div class=" pb-2 pt-3">
<h2><a href="https://merkhaiburch.github.io/projects/contributions/">Science Communication</a></h2>
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</div>
<h3 class="mb-3"><a href="https://merkhaiburch.github.io/projects/contributions/teaching/">Teaching and Outreach</a></h3>
<div class="resume-item d-flex flex-column flex-md-row mb-3">
<div class="resume-content" style="width:200px;">
<img src="/img/eyh_2022.jpg" style="max-height:150px;max-width:150px;"/>
</div>
<div class="resume-date">
<p>I have communicated many different scientific concepts to the broader community through numerous teaching and outreach events.<p>
<p class><a href="https://merkhaiburch.github.io/projects/contributions/teaching/">Read more..</a></p>
</div>
</div>
<div><ul class="tags">
</ul>
</div>
<h3 class="mb-3"><a href="https://merkhaiburch.github.io/projects/contributions/zines/">Zines</a></h3>
<div class="resume-item d-flex flex-column flex-md-row mb-3">
<div class="resume-content" style="width:200px;">
<img src="/img/zine.jpg" style="max-height:150px;max-width:150px;"/>
</div>
<div class="resume-date">
<p>I have created numerous zines for different projects and outreach events as a way to communicate my science to broader audiences.<p>
<p class><a href="https://merkhaiburch.github.io/projects/contributions/zines/">Read more..</a></p>
</div>
</div>
<div><ul class="tags">
</ul>
</div>
</div>
</section>
<section class="resume-section p-3 p-lg-5 d-flex flex-column" id="Publications">
<div class="my-auto" id="projects-content">
<div class=" pb-2 pt-3">
<h2><a href="https://merkhaiburch.github.io/publications/">Publications</a></h2>
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<p class="lead">A short collection of publications. My full list of publications is available on <a href="https://scholar.google.com/citations?user=lvFMbpwAAAAJ&hl=en">Google Scholar</a>.</p>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="publication-content mr-auto">
<h3 class="mb-0">Paper - <a href="https://merkhaiburch.github.io/publications/pleiotropy/">Elucidating the patterns of pleiotropy and its biological relevance in maize</a></h3>
<div>In this paper we investigated the extent to which pleiotropy impacts phenotypes within the maize Nested Association Mapping and Goodman Association Population using GWAS.</div>
<p><ul class="tags">
</ul>
</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">March 2023</span>
<img src="/img/test_pleiotropy_2.png" style="max-width:250px;padding:5px;"/>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="publication-content mr-auto">
<h3 class="mb-0">Paper - <a href="https://merkhaiburch.github.io/publications/yield/">The perils and promise of single-gene solutions to crop yield: extraordinary claims require extraordinary evidence</a></h3>
<div>In this paper we compiled many of the common things that can go wrong in crop productivity experiments and provide a list of recommendations to the community to rigorously measure plant yield.</div>
<p><ul class="tags">
</ul>
</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">March 2023</span>
<img src="/img/resize_yield.jpg" style="max-width:250px;padding:5px;"/>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="publication-content mr-auto">
<h3 class="mb-0">Paper - <a href="https://merkhaiburch.github.io/publications/tcb1/">Genomic mapping of the modifiers of teosinte crossing barrier 1 (Tcb1)</a></h3>
<div>In this paper we used QTL mapping to find modifiers associated with Teosinte crossing barrier 1.</div>
<p><ul class="tags">
</ul>
</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">July 2022</span>
<img src="/img/resize_tcb1.png" style="max-width:250px;padding:5px;"/>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="publication-content mr-auto">
<h3 class="mb-0">Paper - <a href="https://merkhaiburch.github.io/publications/predictive_breeding/">Predictive breeding for maize: Making use of molecular phenotypes, machine learning, and physiological crop models</a></h3>
<div>In this paper we reviewed the history and future of maize predictive breeding.</div>
<p><ul class="tags">
</ul>
</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">March 2020</span>
<img src="" style="max-width:250px;padding:5px;"/>
</div>
</div>
</div>
</section>
<section class="resume-section p-3 p-lg-5 d-flex flex-column" id="experience">
<div class="my-auto" id="experience-content">
<h2 class="mb-5">Experience</h2>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">Graduate Research Assistant</h3>
<div class="subheading mb-3">Cornell University</div>
<p><p>Elucidating the patterns of pleiotropy and its biological relevance in maize AND Regulatory Adaptation of Transposable Elements and Their Effect on Gene Expression in Maize and the Andropogoneae.</p>
<ul>
<li>I curated and mapped 120,549 traits across two diverse maize populations to uncover the patterns of pleiotropy. Created machine learning models to describe how pleiotropic loci were biologically regulated.</li>
<li>Developed a novel gene expression quantification pipeline suited towards highly diverse genomes to test how transposable elements impact gene expression.</li>
<li>Lead a highly collaborative team to write a perspective on why genomic prediction will be the solution to increasing intrinsic crop yield.</li>
</ul>
</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">August 2018 - Present</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">Graduate Teaching Assistant</h3>
<div class="subheading mb-3">Cornell University</div>
<p><p>Taught two sections of Plant Genetics (PLBRG 2250). Responsibilities included:</p>
<ul>
<li>Created lab materials (quizzes, lab lectures, slides, pre-lab videos).</li>
<li>Graded exams.</li>
<li>Ran experiments with students.</li>
</ul>
</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">January 2021 - May 2021</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">Graduate Research Assistant</h3>
<div class="subheading mb-3">South Dakota State University</div>
<p>Used QTL mapping to identify modifiers of the teosinte crossing barrier 1 locus in maize using the Intermated B73 x Mo17 population and identified numerous candidate loci. For my second project, I sequenced and assembled the genomes of two male gametophyte mutants and identified candidate causal loci for pollen development.</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">July 2016 - August 2018</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">Research Student Assistant</h3>
<div class="subheading mb-3">USDA ARS PBARC</div>
<p><p>Investigating axis formation in Mediterranean fruit flies.</p>
<ul>
<li>Designed and analyzed experimental data for a time series gene expression experiment on fruit-fly eggs.</li>
<li>Validated numerous RNAi experiments through gene expression assays.</li>
</ul>
</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">September 2015 - May 2016</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">REU Research Scholar</h3>
<div class="subheading mb-3">University of Nebraska Lincoln</div>
<p>Worked on multiple projects looking at Arabidopsis thaliana snRNA processing and miRNA biogenesis and activity. Screened and backcrossed mutants defective in pollen and embryo development.</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">Summer 2015</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">Laboratory Assistant</h3>
<div class="subheading mb-3">Hilo Core Genetics Facility</div>
<p>Taught two workshops on DNA extraction for the non-science community (East Hawaii 4-H club, UH Hilo outreach day). I also ran and taught core facility users how to perform DNA extractions, design RT-PCR experiments, set up IonTorret sequencing libraries and runs, and use facility instruments.</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">January 2015 - May 2015</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">Molecular Laboratory Assistant</h3>
<div class="subheading mb-3">University of Hawaii at Hilo</div>
<p>Using DNA extraction, PCR, and Sanger sequencing I amplified genetic markers to create and deliver phylogeographic trees of Metrosideros polymorpha to understand the speciation process of these trees across the Hawaiian Islands.</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">November 2014 - June 2015</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">REU Research Scholar</h3>
<div class="subheading mb-3">South Dakota State University</div>
<p><p>Plant microbe interactions affect the biomass production of Spartina pectinata, a potential bioenergy crop.</p>
<ul>
<li>Collected and analyzed data on phosphorous content in roots and shoots, arbuscular mycorrhizae prevalence, and harvested tissue for RNA sequencing.</li>
</ul>
</p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">Summer 2014</span>
</div>
</div>
</div>
</section>
<section class="resume-section p-3 p-lg-5 d-flex flex-column" id="education">
<div class="my-auto">
<h2 class="mb-5">Education</h2>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">Cornell University</h3>
<div class="subheading mb-3">Doctor of Philosophy</div>
<div>Plant Genetics</div>
<p>Expected Graduation: December 2023
</div>
<div class="resume-date text-md-right">
<span class="text-primary">2018 - 2023</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">South Dakota State University</h3>
<div class="subheading mb-3">Master of Science</div>
<div>Biology</div>
<p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">2016 - 2018</span>
</div>
</div>
<div class="resume-item d-flex flex-column flex-md-row mb-5">
<div class="resume-content mr-auto">
<h3 class="mb-0">University of Hawaii at Hilo</h3>
<div class="subheading mb-3">Bachelor of Science</div>
<div>Biology</div>
<p>
</div>
<div class="resume-date text-md-right">
<span class="text-primary">2012 - 2016</span>
</div>
</div>
</div>
</section>
<section><span style="color: #999999;">Nifty <a href="https://codepen.io/wbeeftink/pen/dIaDH">tech tag lists</a> from <a class="pen-owner-link" href="https://codepen.io/wbeeftink">Wouter Beeftink</a> </span>
</section>
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