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does not have enough regulatory connection in the GRNs. Cannot perform simulation. #205

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xiaomaolxc opened this issue Jul 6, 2024 · 0 comments

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@xiaomaolxc
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Hi,
a very great tool, I discovered a problem during testing that I found difficult to solve.
When I was testing gene knockout, I found that the tool seemed to require the gene to be a transcription factor, but in some cases, I wanted to simulate that the knocked out gene was not a transcription factor, but only a regulated target gene.
So in this case, I added the gene to TF Target in order to simulate knockout, but the problem mentioned above still occurred later, as shown in the image below
image
image
I referred to the solution to this problem:
#49
I would greatly appreciate it if you could provide valuable feedback.

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