Applicability to scRNA-seq Data

[DarioS]

Has it been evaluated for scRNA-seq data? I have three pairwise comparisons of twenty samples and five cell types. I see fifteen warnings of the form Only 1 bin; IHW reduces to Benjamini Hochberg (uniform weights). However, for Q-Q plots of p-values I see divergence from the diagonal for some of the comparisons, suggesting there are differentially expressed genes to be found.