diff --git a/.github/workflows/pipx.yml b/.github/workflows/pipx.yml
new file mode 100644
index 0000000..760da43
--- /dev/null
+++ b/.github/workflows/pipx.yml
@@ -0,0 +1,33 @@
+name: pipx integration
+on:
+  push:
+    branches: [ main ]
+  pull_request:
+    branches: [ main ]
+  workflow_dispatch:
+
+jobs:
+  integration:
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [macos-latest, ubuntu-latest]
+        python: ["3.8", "3.10", "3.12"]
+
+    runs-on: ${{ matrix.os }}
+    steps:
+      - name: Clone gyp-next
+        uses: actions/checkout@v4
+      - uses: actions/setup-python@v5
+        with:
+          python-version: ${{ matrix.python }}
+          allow-prereleases: true
+      - name: Setup dependencies
+        shell: bash
+        run: |
+          python3 -m pip install --user pipx
+      - name: Integration test with pipx
+        shell: bash
+        run: |
+          pipx run --no-cache --spec ./ gyp --help
+          pipx run --no-cache --spec ./ gyp --version