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[NTR] Placental new terms - extravillous trophoblast cells + uterine macrophage #2259

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aleixpuigb opened this issue Jan 5, 2024 · 0 comments · Fixed by #2262
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[NTR] Placental new terms - extravillous trophoblast cells + uterine macrophage #2259

aleixpuigb opened this issue Jan 5, 2024 · 0 comments · Fixed by #2262
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HuBMAP Needed/useful for HuBMAP new term request

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aleixpuigb commented Jan 5, 2024

Preferred term label:
interstitial extravillous trophoblast cell

Synonyms
interstitial extravillous trophoblast PMID:37630754
iEVT PMID:37630754

Definition (free text, please give PubMed ID)
An extravillous trophoblast cell that invades the uterine wall to anchor the placenta to the uterus. PMID:37630754

Parent term (use https://www.ebi.ac.uk/ols/ontologies/uberon)
trophoblast cell
'develops from' some 'extravillous trophoblast'

Your nano-attribution (ORCID)
https://orcid.org/0000-0001-6677-8489


Preferred term label:
endovascular extravillous trophoblast cell

Synonyms
endovascular extravillous trophoblast PMID:37630754
eEVT PMID:37630754

Definition (free text, please give PubMed ID)
An extravillous trophoblast cell that invades the maternal spiral arteries and replace the endothelial lining, remodeling the vessels and allowing for adequate blood transport into the placenta. PMID:37630754

Parent term (use https://www.ebi.ac.uk/ols/ontologies/uberon)
trophoblast cell
'develops from' some 'extravillous trophoblast'

Comment
Shortly after implantation, the endovascular extravillous trophoblast cells occlude the maternal spiral arteries, preventing premature oxygen delivery to the placental villi and reducing fetal oxidative stress. PMID:37630754

Your nano-attribution (ORCID)
https://orcid.org/0000-0001-6677-8489


Preferred term label
uterine macrophage

Synonyms (add reference(s), please)

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)
A tissue-resident macrophage that is part of some uterus. PMID:36113384

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
'tissue-resident macrophage'

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
'part of' some uterus

Your ORCID
https://orcid.org/0000-0001-6677-8489

Additional notes or concerns
Uterine macrophages are reported to be evenly distributed throughout the endometrial stroma but with aggregations observed close to the lumen of superficial secretory glands. (Should be added as has part in endometrial stroma) PMID:36113384

@aleixpuigb aleixpuigb added new term request HuBMAP Needed/useful for HuBMAP labels Jan 5, 2024
@aleixpuigb aleixpuigb self-assigned this Jan 5, 2024
aleixpuigb added a commit that referenced this issue Jan 8, 2024
Addresses #2259 NTR placental terms
@aleixpuigb aleixpuigb linked a pull request Jan 8, 2024 that will close this issue
aleixpuigb added a commit that referenced this issue Jan 9, 2024
* Addresses #2259 NTR placental terms

Addresses #2259 NTR placental terms

* Minor edit definition
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