diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl
index 1d8c594f4..449a8b131 100644
--- a/src/ontology/cl-edit.owl
+++ b/src/ontology/cl-edit.owl
@@ -4300,6 +4300,7 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000092 "chondroclast")
 AnnotationAssertion(rdfs:comment obo:CL_0000092 "Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid.")
 AnnotationAssertion(rdfs:label obo:CL_0000092 "osteoclast")
 EquivalentClasses(obo:CL_0000092 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001474) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001850) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001937) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000001944) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000007597) ObjectSomeValuesFrom(obo:BFO_0000051 obo:PR_000011178) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001954) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000002062) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045453)))
+SubClassOf(obo:CL_0000092 obo:CL_0000518)
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000092 obo:CL_0000766)
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000092 obo:CL_0001035)
 SubClassOf(obo:CL_0000092 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000576))
@@ -4500,6 +4501,7 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000113 "BTO:0001433")
 AnnotationAssertion(rdfs:label obo:CL_0000113 "mononuclear phagocyte")
 EquivalentClasses(obo:CL_0000113 ObjectIntersectionOf(obo:CL_0000518 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407)))
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000113 obo:CL_0000518)
+SubClassOf(obo:CL_0000113 obo:CL_0000842)
 
 # Class: obo:CL_0000114 (surface ectodermal cell)
 
@@ -5643,6 +5645,7 @@ AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0000235 "histiocyte")
 AnnotationAssertion(rdfs:comment obo:CL_0000235 "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.")
 AnnotationAssertion(rdfs:label obo:CL_0000235 "macrophage")
 EquivalentClasses(obo:CL_0000235 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0006909) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0031268)))
+SubClassOf(obo:CL_0000235 obo:CL_0000113)
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000235 obo:CL_0000766)
 SubClassOf(obo:CL_0000235 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000576))
 
@@ -7206,6 +7209,7 @@ AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000451 "interdigitating c
 AnnotationAssertion(oboInOwl:hasRelatedSynonym obo:CL_0000451 "veiled cell")
 AnnotationAssertion(rdfs:label obo:CL_0000451 "dendritic cell")
 EquivalentClasses(obo:CL_0000451 ObjectIntersectionOf(obo:CL_0000738 ObjectSomeValuesFrom(obo:BFO_0000051 obo:GO_0042613) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001002) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001003) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001020) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001024) ObjectSomeValuesFrom(obo:CL_4030046 obo:PR_000001289) ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0001816) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0002504) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0019882) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0045580)))
+SubClassOf(obo:CL_0000451 obo:CL_0000113)
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000451 obo:CL_0000738)
 DisjointClasses(obo:CL_0000451 obo:CL_0000542)
 
@@ -8294,6 +8298,7 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000576 "FMA:62864")
 AnnotationAssertion(rdfs:comment obo:CL_0000576 "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid.")
 AnnotationAssertion(rdfs:label obo:CL_0000576 "monocyte")
 EquivalentClasses(obo:CL_0000576 ObjectIntersectionOf(obo:CL_0000766 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001407) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030225) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030316) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0043011)))
+SubClassOf(obo:CL_0000576 obo:CL_0000113)
 SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000576 obo:CL_0000766)
 SubClassOf(obo:CL_0000576 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000559))