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Drafting a plan for pre-coordinating amerliorated an excacerbated phenotypes #59
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I suspect that Here is what I mean by genetic suppression and enhancement:
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For ZFIN ameliorated and exacerbated phenotypes can be the result of genetic interactions or application of treatments (chemicals, drugs) or both. |
Apart from phenotypic abnormalities, ZFIN curates ameliorated and excacerbated phenotypes. These phenotypes are special in two senses
Now the problem is that (1) adding those into ZP will lead to two large branches with 3000 - 9000 terms being added (term proliferation), and (2) there is no integration between the two, or, indeed with anything in uPheno.
My sense is the ship to prevent term proliferation has sailed. We should just add these phenotypes the same way as the we have the others.
However, I do think we should move uPheno to the "changed" qualifier throughout so that we can group ameliorated, exacerbated and abnormal in a more general "phenotype" hierarchy.
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