HealthCondition entity transition

[roll]

Background
Related to #21 issue.

Topic

HealthCondition - illness, injury, impairment etc

In our ideal data model we have the next fields:

• MEDDRA
• WHO-ICD-10

But in the Cochrane Database we have only:

• Description like A - Delusional Disorder

Question
How we have to sync it?

Comments
MedDRA - https://en.wikipedia.org/wiki/MedDRA
WHO-ICD-10 - http://www.who.int/classifications/icd/en/

See also - https://github.com/okfn/opentrials-cochrane-schizophrenia-data/wiki

[pwalsh]

Looks like we can't resolve this to a code list like WHO-ICD-10, at least not now. It might be something we'd aim for in later work - semi-automated process of resolving descriptions of stuff (like health condition in this case) into structured data (WHO list of health conditions).

[danfowler]

@pwalsh @roll yeah, taking a look at the WHO-ICD-10 list, it would seem a non-straightforward task linking one to the other.

Another question: each HealthCareCondition starts with a code indicating one of "Major Illness", "Minor Illness", "State" (e.g. remission, chronic), "Stage" (e.g. early onset), and "Healthcare Problem" (e.g. "Epilepsy", "Employment" (?)). I wonder if those classifications should be added to the ideal model. Or maybe just free text?

[pwalsh]

@danfowler seems we might be able to extract that in a structured way?

[danfowler]

@pwalsh as an example of the syncing problem: "Epilepsy" is an example HealthCareCondition. In the WHO-ICD-10 list, it could be represented by "Epilepsy", "Other epilepsy", "Epilepsy, unspecified", or "Other generalized epilepsy and epileptic syndromes".

[roll]

"A - Delusional Disorder"
"A - Health Care Professionals"
"A - Healthy volunteers"
"A - Lay carers/family"
"A - Schizoaffective disorders"
"A - Schizophrenia"
"B - No Minority"
"B - Delusional disorder"
"B - Health care professionals"
"B - Healthy volunteers"
"B - Lay carers/family"
"B - Psychotic"
"B - Schizoaffective disorders"
"B - Schizophrenia"
"B - Serious mental illness"
"C - Not applicable"
"C - Acute"
"C - Early post-acute"
"C - Remission"
"D - Not applicable"
"D - Prodromal illness"
"D - First Episode"
"D - Early illness"
"D - Persistent / chronic"
"D - Late onset"
"E - Aggression (RE Aggression)"
"E - Agitation (RE Aggression)"
"E - Akathisia"
"E - Depression"
"E - Movement disorders"
"E - Negative symptoms"
"E - Not Applicable"
"E - Parkinsonism"
"E - Tardive Dyskinesia"
"E - Treatment Resistant"
"E - Weight Gain"
"C - Partial remission"
"E - Adherence"
"C - State Not Described"
"D - Stage not described"
"A - Schizotypal"
"C - Suspected"
"B - Schizophreniform"
"E - Relapse"
"E - Neurocognition"
"E - Substance Abuse (Substance Abuse)"
"E - Anxiety (RE Aggression)"
"B - Schizotypal"
"E - Mood disorder"
"E - Alcohol (Substance Abuse)"
"E - Withdrawal"
"E - Obsessive compulsive symptoms"
"E - Positive symptoms"
"E - Amenorrhea"
"E - Sialorrhea (Hypersalivation)"
"E - Hypersalivation"
"E - Delusions"
"E - Adverse effects"
"A - Schizophreniform"
"E - Mammogen level"
"E - Social function"
"E - Prolactin level"
"E - Cognitive function"
"E - Compliance"
"E - Excitement (RE Aggression)"
"E - Abnormal ECG"
"E - Memory"
"E - Electrocardiogram"
"E - Glucose metabolism"
"E - Self-esteem"
"E - Erythrocyte sedimentation rate"
"E - Constipation"
"E - Paralytic ileus"
"E - Enuresis"
"E - Urinary retention"
"E - Liver function"
"E - Sinus tachycardia"
"E - Xerostomia"
"E - Behaviour"
"E - Glucose and lipid metabolism"
"E - Extrapyramidal symptoms"
"E - Glucose level"
"E - Immunity"
"E - Tremor"
"E - Leukopenia"
"E - Potassium level"
"E - Blood pressure"
"E - Blood glucose"
"E - Electroencephalogram"
"E - Emotion and social function"
"E - Negative emotions"
"E - Growth Hormone Level"
"E - Blood lipid"
"E - Blood concentration"
"E - Salivation"
"E - Expressed emotion and relapse"
"E - Glutamate level"
"E - Adverse events"
"E - Negative behaviour"
"E - Executive function"
"E - Blood Drug Level"
"E - Menstruation"
"E - Hepatic dysfunction"
"E - Spinal fracture"
"E - Negative + Positive symptoms"
"E - Metabolic syndrome"
"E - Dystonia"
"E - Polysialia adverse effects"
"E - Serum prolactin level"
"E - Serum lipid"
"E - Emotional disorder"
"E - Decubitus"
"E - Health education"
"E - Low self-esteem"
"E - Lipid metabolic"
"E - Dysphrenia"
"E - Function improvement"
"E - Hallucinations"
"E - Diabetes mellitus"
"E - Leucocyte"
"E - Metabolism"
"E - Sex hormone level"
"E - Glycometabolism"
"A - Psychotic"
"A - Serious Mental Illness"
"E - Polydipsia-hyponatremia"
"E - Cardiovascular autonomic reactivity"
"E - Learning disability"
"E - Hypnotic action"
"E - Heart disease"
"E - Homelessness"
"E - Cardiovascular disease"
"E - Sexual functioning"
"E - Decomposition"
"E - Post-psychotic depression"
"E - Hyperlipidemia"
"E - Visual hypersensitivity attack"
"E - Influence of comorbid personality disorder and serious mental illness on police contacts"
"E - Erectile dysfunction"
"E - Suicide"
"E - Dementia"
"E - Hyperprolactinemia"
"E - Breast Cancer"
"E - Jail Recidivism"
"E - Early response to treatment"
"E - Cholesterol"
"E - Endogenous depression"
"E - Sleep"
"E - Sweat odour"
"E - Eye abnormalities"
"E - Metabolic disorder"
"E - Hyperhomocysteinemia"
"E - Attention"
"E - EEG"
"E - C-reactive protein levels"
"E - interleukin level"
"E - Anhedonia"
"E - Oral hygiene"
"E - Cardiac outcomes"
"E - Smoking (Substance Abuse)"
"E - HIV"
"E - Stigma"
"E - Exacerbation (RE Aggression)"
"E - Economic"
"E - Hypertension"
"E - Hypotonic disorders"
"E - Mental retardation"
"E - Digestion"
"E - Defective cerebral circulation"
"E - Cannabis Use (Substance Abuse)"
"E - Disturbed"
"E - Neuroleptic resistant"
"E - Polydipsia"
"E - Psychopathology"
"E - Neurocognitive Deficits"
"E - Early onset"
"E - Engagement"
"E - Employment"
"E - Dual diagnosis"
"E - Insulin"
"E - Self-perception"
"e - Dystonia-parkinsonism"
"E - Herpes"
"E - Rehabilitation"
"E - Voices"
"E - PTSD"
"E - Exercise"
"E - Independent living"
"E - Mental disability"
"E - Paranoia"
"E - Offenders"
"E - Postmenopausal"
"E - Cognition"
"E - Social cognition"
"E - Eye movements"
"E - Amphetamine (Substance Abuse)"
"E - Diet (Weight)"
"E - Comorbid"
"E - HSVI"
"E - Insomnia"
"E - Sensory gating"
"E - Quality of life"
"E - Stress"
"E - Obesity (Weight)"
"E - Excitement and Agitation (RE Aggression)"
"A - At Risk of Psychosis"
"A - Family History of Psychosis"
"A - Mental Illness"
"A - Not Described"
"D - Chronic"
"E - Cardiovascular Risk Factor"
"E - Childhood Learning Disabilities"
"E - Drug Dependence (Substance Abuse)"
"E - Nicotine Dependence (Substance Abuse)"
"E - Cocaine Dependence (Substance Abuse)"
"E - Cognitive Impairment"
"E - Comorbidity"
"E - Diabetes"
"E - Dually Diagnosed"
"E - Diminished P50 Sensory Gating"
"E - Discrimination"
"E - Drug and Alcohol Use (Substance Abuse)"
"E - ECT-Induced Cognitive Impairment"
"E - Epilepsy"
"E - Gliadin-Positive"
"E - Hepatitis"
"E - Herpes Simplex"
"E - Methamphetamine Dependence (Substance Abuse)"
"E - Hyperglycemia"
"E - Muteness"
"E - Non-Adherence"
"E - Hyperprolinemia"
"E - Impulsivity"
"E - Marked Social Withdrawal"
"E - Opioid Dependence (Substance Abuse)"
"E - Overweight"
"E - Pathological Gambling"
"E - Postmenopause"
"E - Prolactinemia"
"E - Restless Legs Syndrome"
"E - Substance Use (Substance Abuse)"
"E - Unemployment"
"E - Violence (RE Aggression)"
"A - Tardive Dyskinesia"
"E - Asthma"
"E - COPD"
"E - Compulsory Admission (RE Aggression)"
"E - Pregnancy"
"E - At Risk of Psychosis"
"E - Acutely Disturbed (RE Aggression)"
"A - Delirium"
"A - Illness"
"E - Chronic HCV Infection"
"E - Galactorrhea-Amenorrhea Syndrome"
"E - Psychiatric Illness"
"E - Suicidal Ideation"

[roll]

I've listed it here to ask like in the #16 issue. It's just 256 items - may be we will be able to clean (sync with ICD-10) it by hands on the next stage? @danfowler

[danfowler]

Yes, we can try to sync it. I just worry that there might be some amount of subjectivity here.