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Interventions

Gitter Issues Docs

A Data Package which is a database of public and private sources of information on interventions related to clinical trials.

In addition, this README tries to provide some guidance on how one could take info from these multiple resources to create a new, normalized list of drugs.

NDC

One way to link at least some of these databases is through the NDC. The NDC, or National Drug Code, is a unique 10-digit, 3-segment number. It is a universal product identifier for human drugs in the United States. This is used by both DrugBank and FDA.

DrugBank XML

<product>

    <name>Pulmozyme</name>
    <ndc-id>50242-100\_1f306717-b937-4efc-a269-bcadda447cce</ndc-id>
    <ndc-product-code>50242-100</ndc-product-code>
    ...

API request for 50242-100 on FDA.

MeSH

Drugs (interventions) may also be linked to trials (in ClinicialTrials.gov) via MeSH. The following XML snippet from NCT00420498 associates this trial with a drug term found in MeSH.

Clinical Trials XML

<intervention_browse>
    <!-- CAUTION: The following MeSH terms are assigned with an imperfect 
         algorithm -->
    <mesh_term>Atomoxetine</mesh_term>
</intervention_browse>