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Outline of approach #1

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4 of 5 tasks
djinnome opened this issue May 1, 2024 · 0 comments
Open
4 of 5 tasks

Outline of approach #1

djinnome opened this issue May 1, 2024 · 0 comments
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@djinnome
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djinnome commented May 1, 2024

  1. compute FVA on reference condition.
  2. Use enzyme activity data to modify the bounds for non-reference conditions
  3. Use external flux measurements to modify the bounds for the non-reference external fluxes
  4. run E-flux with slack variables to compute the condition-specific flux distribution.
  5. Create a triangular distribution where
  • lower = lower - slack
  • upper = upper + slack
  • center = E-flux flux
@djinnome djinnome self-assigned this May 1, 2024
@ShantMahserejian ShantMahserejian linked a pull request May 7, 2024 that will close this issue
@djinnome djinnome removed a link to a pull request May 7, 2024
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