diff --git a/src/app/config/doc-config.json b/src/app/config/doc-config.json
index 9f7433ce..54f566d0 100644
--- a/src/app/config/doc-config.json
+++ b/src/app/config/doc-config.json
@@ -214,6 +214,7 @@
       "faq/what-file-formats-can-i-use-submit-high-throughput-data" : "What file formats can I use to submit high-throughput data?",
       "faq/what-gff3" : "What is GFF3?",
       "faq/what-go-term-enrichment-how-can-i-do-it-my-genes" : "What is GO term enrichment? How can I do it for my genes?",
+      "faq/what-pombemine-service-url" : "What is the PombeMine service URL",
       "faq/what-psl-format" : "What is PSL format?",
       "faq/what-vcf" : "What is VCF?",
       "faq/what-wig-format" : "What is WIG format?",
@@ -465,6 +466,7 @@
       "news/2023-06-19-rhea-reaction-diagrams" : "Reaction diagrams on term pages",
       "news/2023-07-27-protein-feature-viewer" : "Protein feature viewer added to gene pages",
       "news/2023-09-20-list-of-publication-genes" : "Accessing the list of genes from a paper",
+      "news/2023-09-30-nomenclature-paper" : "Revised fission yeast nomenclature for genes and alleles",
       "news/index" : "News archive",
       "status" : "Genome Status",
       "status/centromeres" : "Centromeres",
diff --git a/src/app/config/docs.json b/src/app/config/docs.json
index 858d73f1..a63bbf99 100644
--- a/src/app/config/docs.json
+++ b/src/app/config/docs.json
@@ -50,7 +50,7 @@
       "id" : "about/projects"
    },
    {
-      "content" : "\n\nPlease see the Citing PomBase page, which lists papers to cite for PomBase, the S. pombe genome sequence, Canto, FYPO, annotations and Compara.\n\nJournal articles\n\nAlayne Cuzick, James Seager, Valerie Wood, Martin Urban, Kim Rutherford, Kim E Hammond-Kosack\nA framework for community curation of interspecies interactions literature\neLife, 12:e84658\n\n10.7554/eLife.84658\n\nGene Ontology Consortium.\nThe Gene Ontology knowledgebase in 2023\nGenetics, Volume 224, Issue 1, May 2023, iyad031\n\n10.1093/genetics/iyad031\n\nVivian Monzon, Typhaine Paysan-Lafosse, Valerie Wood, Alex Bateman\nReciprocal Best Structure Hits: Using AlphaFold models to discover distant homologues\nBioinformatics Advances, October 2022, vbac072\n\n10.1093/bioadv/vbac072\n\nValérie de Crécy-lagard et al. (including Val Wood)\nA roadmap for the functional annotation of protein families: a community perspective\nDATABASE, Volume 2022, August 2022, baac062\n\nPMID:35961013 10.1093/database/baac062\n\nValerie Wood, Paul W Sternberg, Howard D Lipshitz\nMaking biological knowledge useful for humans and machines\nGenetics, Volume 220, Issue 4, April 2022, iyac001\n\nPMID:35380659 10.1093/genetics/iyac001\n\nHarris MA, Rutherford KM, Hayles J, Lock A, Bähler J, Oliver S, Mata J, Wood V\nFission stories: Using PomBase to understand Schizosaccharomyces pombe biology\nGenetics, Volume 220, Issue 4, April 2022, iyab222\n\nPMID:35100366 10.1093/genetics/iyab222\n\nRutherford KM, Harris MA, Oliferenko S, Wood V\nJaponicusDB: rapid deployment of a model organism database for an emerging model species\nGenetics, Volume 220, Issue 4, April 2022, iyab223\n\nPMID:35380656 10.1093/genetics/iyab223\n\nUrban M, Cuzick A, Seager J, Wood V, Rutherford K, Venkatesh SY, Sahu J, Vijaylakshmi Iyer S, Khamari L, De Silva N, Martinez MC, Pedro H, Yates AD, Hammond-Kosack KE\nPHI-base in 2022: a multi-species phenotype database for Pathogen–Host Interactions\nNAR, Volume 50, Issue D1, 7 January 2022, Pages D837–D847\n\nPMID:34788826 10.1093/nar/gkab1037\n\nGene Ontology Consortium.\nThe Gene Ontology resource: enriching a GOld mine.\nNucleic Acids Res. 2021 Jan 8;49(D1):D325-D334.\n\nPMID:33290552 DOI:10.1093/nar/gkaa1113\n\nWood V, Carbon S, Harris MA, Lock A, Engel SR, Hill DP, Van Auken K, Attrill H, Feuermann M, Gaudet P, Lovering RC, Poux S, Rutherford KM, Mungall CJ.\nTerm Matrix: a novel Gene Ontology annotation quality control system based on ontology term co-annotation patterns.\nOpen Biol 2020 Sep;10(9):200149\n\nPMID:32875947 DOI:10.1098/rsob.200149\n\nShefchek KA et al. (including Harris MA).\nThe Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species.\nNucleic Acids Res. 2020 Jan 8;48(Database issue): D704-D715.\n\nPMID:31701156 DOI:10.1093/nar/gkz997\n\nUrban M, Cuzick A, Seager J, Wood V, Rutherford K, Venkatesh SY, De Silva N, Martinez MC, Pedro H, Yates AD, Hassani-Pak K, Hammond-Kosack KE.\nPHI-base: the pathogen-host interactions database.\nNucleic Acids Res. 2020 Jan 8;48(Database issue): D613-D620.\n\nPMID:31733065 DOI:10.1093/nar/gkz904\n\nLock A, Harris MA, Rutherford K, Hayles J, Wood V.\nCommunity curation in PomBase: enabling fission yeast experts to provide detailed, standardized, sharable annotation from research publications.\nDatabase (Oxford) 2020 Jan 1;2020. pii: baaa028.\n\nPMID:32353878 DOI:10.1093/database/baaa028\n\nDikicioglu D, Nightingale DJH, Wood V, Lilley KS, Oliver SG.\nTranscriptional regulation of the genes involved in protein metabolism and processing in Saccharomyces cerevisiae.\n* FEMS Yeast Res.* 2019 Mar 1;19(2):foz014.\n\nPMID:30753445 DOI:10.1093/femsyr/foz014\n\nWood V, Lock A, Harris MA, Rutherford K, Bähler J, Oliver SG.\nHidden in plain sight: What remains to be discovered in the eukaryotic proteome?\nOpen Biol 2019 Feb 28;9(2):180241.\n\nPMID:30938578 DOI:10.1098/rsob.180241\n\nThe Gene Ontology Consortium.\nThe Gene Ontology Resource: 20 years and still GOing strong.\nNucleic Acids Res. 2019 Jan 8;47(Database issue):D330-D338.\n\nPMID:30395331 DOI:10.1093/nar/gky1055\n\nThe RNAcentral Consortium.\nRNAcentral: a hub of information for non-coding RNA sequences.\nNucleic Acids Res. 2019 Jan 8;47(Database issue):D221-D229. Epub 2018 Nov 5.\n\nPMID:30395267 DOI:10.1093/nar/gky1034 (Correction in DOI:10.1093/nar/gky1206)\n\nLock A, Rutherford K, Harris MA, Hayles J, Oliver SG, Bähler J; Wood V.\nPomBase 2018: user-driven reimplementation of the fission yeast database provides rapid and intuitive access to diverse, interconnected information.\nNucleic Acids Res. 2019 Jan 8;47(Database issue): D821-D827. Epub 2018 Oct 13.\n\nPMID:30321395 DOI:10.1093/nar/gky961\n\nGene Ontology Consortium.\nAnnotation of gene product function from high-throughput studies using the Gene Ontology.\nDatabase (Oxford). 2019 Jan 1;2019:baz007.\n\nPMID:30715275 DOI:10.1093/database/baz007\n\nUrban M, Cuzick A, Rutherford K, Irvine A, Pedro H, Pant R, Sadanadan V, Khamari L, Billal S, Mohanty S, Hammond-Kosack KE.\nPHI-base: a new interface and further additions for the multi-species pathogen-host interactions database.\nNucleic Acids Res. 2017 Jan 4;45(D1):D604-D610. Epub 2016 Dec 3.\n\nPMID:27915230 DOI:10.1093/nar/gkw1089\n\nThe Gene Ontology Consortium\nExpansion of the Gene Ontology knowledgebase and resources.\nNucleic Acids Res. 2017 Jan 4;45(D1):D331-D338. Epub 2016 Nov 29.\n\nPMID:27899567 DOI:10.1093/nar/gkw1108\n\nThe RNAcentral Consortium\nRNAcentral: a comprehensive database of non-coding RNA sequences.\nNucleic Acids Res. 2017 Jan 4;45(D1):D128-D134. Epub 2016 Oct 28.\n\nPMID:27794554 DOI:10.1093/nar/gkw1008\n\nHuntley RP, Sitnikov D, Orlic-Milacic M, Balakrishnan R, D’Eustachio P, Gillespie ME, Howe D, Kalea AZ, Maegdefessel L, Osumi-Sutherland D, Petri V, Smith JR, Van Auken K, Wood V, Zampetaki A, Mayr M, Lovering RC.\nGuidelines for the functional annotation of microRNAs using the Gene Ontology.\nRNA. 2016 May;22(5):667-76. Epub 2016 Feb 25.\n\nPMID:26917558 DOI:10.1261/rna.055301.115\n\nOliver SG, Lock A, Harris MA, Nurse P, Wood V.\nModel organism databases: essential resources that need the support of both funders and users.\nBMC Biol. 2016 14(1): 49.\n\nPMID:27334346 DOI:10.1186/s12915-016-0276-z\n\nBitton DA, Schubert F, Dey S, Okoniewski M, Smith GC, Khadayate S, Pancaldi V, Wood V, Bähler J.\nAnGeLi: A Tool for the Analysis of Gene Lists from Fission Yeast.\nFront Genet. 2015 Nov 16;6:330. eCollection 2015.\n\nPMID:26635866 DOI:10.3389/fgene.2015.00330\n\nHoffman CS, Wood V, Fantes PA.\nAn Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System.\nGenetics. 2015 Oct;201(2):403-23.\n\nPMID:26447128 DOI:10.1534/genetics.115.181503\n(Erratum in PMID:26953269 DOI:10.1534/genetics.116.187088)\n\nGene Ontology Consortium\nGene Ontology Consortium: going forward.\nNucleic Acids Res. 2015 Jan;43(Database issue):D1049-56. Epub 2014 Nov 26.\n\nPMID:25428369 DOI:10.1093/nar/gku1179\n\nMcDowall MD, Harris MA, Lock A, Rutherford K, Staines DM, Bähler J, Kersey PJ, Oliver SG, Wood V.\nPomBase 2015: updates to the fission yeast database.\nNucleic Acids Res. 2015 Jan;43(Database issue):D665-61. Epub 2014 Oct 31.\n\nPMID:25361970 DOI:10.1093/nar/gku1040\n\nDikicioglu D, Wood V, Rutherford KM, McDowall MD, Oliver SG.\nImproving functional annotation for industrial microbes: a case study with Pichia pastoris.\nTrends Biotechnol. 2014 Aug;32(8):396-9. Epub 2014 Jun 11.\n\nPMID:24929579 DOI:10.1016/j.tibtech.2014.05.003\n\nAlam-Faruque Y, Hill DP, Dimmer EC, Harris MA, Foulger RE, Tweedie S, Attrill H, Howe DG, Thomas SR, Davidson D, Woolf AS, Blake JA, Mungall CJ, O’Donovan C, Apweiler R, Huntley RP.\nRepresenting kidney development using the gene ontology.\nPLoS One. 2014 Jun 18;9(6):e99864. eCollection 2014.\n\nPMID:24941002 DOI:10.1371/journal.pone.0099864\n\nHuntley RP, Harris MA, Alam-Faruque Y, Blake JA, Carbon S, Dietze H, Dimmer EC, Foulger RE, Hill DP, Khodiyar VK, Lock A, Lomax J, Lovering RC, Mutowo-Meullenet P, Sawford T, Van Auken K, Wood V, Mungall CJ.\nA method for increasing expressivity of Gene Ontology annotations using a compositional approach.\nBMC Bioinformatics. 2014 May 21;15:155.\n\nPMID:24885854 DOI:10.1186/1471-2105-15-155.\n\nRutherford KM, Harris MA, Lock A, Oliver SG, Wood V.\nCanto: An online tool for community literature curation.\nBioinformatics. 2014 Jun 15;30(12):1791-2. Epub 2014 Feb 25.\n\nPMID:24574118 DOI:10.1093/bioinformatics/btu103\n\nHill DP, Adams N, Bada M, Batchelor C, Berardini TZ, Dietze H, Drabkin HJ, Ennis M, Foulger RE, Harris MA, Hastings J, Kale NS, de Matos P, Mungall CJ, Owen G, Roncaglia P, Steinbeck C, Turner S, Lomax J.\nDovetailing biology and chemistry: integrating the Gene Ontology with the ChEBI chemical ontology.\nBMC Genomics. 2013 Jul 29;14:513.\n\nPMID:23895341 DOI:10.1186/1471-2164-14-513\n\nBalakrishnan R1, Harris MA, Huntley R, Van Auken K, Cherry JM.\nA guide to best practices for Gene Ontology (GO) manual annotation.\nDatabase (Oxford). 2013 Jul 9;2013:bat054. Print 2013.\n\nPMID:23842463 DOI:10.1093/database/bat054.\n\nHayles J, Wood V, Jeffery L, Hoe KL, Kim DU, Park HO, Salas-Pino S, Heichinger C, Nurse P.\nA genome-wide resource of cell cycle and cell shape genes of fission yeast.\nOpen Biol. 2013 May 22;3(5):130053.\n\nPMID:23697806 DOI:10.1098/rsob.130053\n\nGene Ontology Consortium\nGene Ontology annotations and resources.\nNucleic Acids Res. 2013 Jan;41(Database issue):D530-5. Epub 2012 Nov 17.\n\nPMID:23161678 DOI:10.1093/nar/gks1050\n\nHarris MA, Lock A, Bähler J, Oliver SG, Wood V.\nFYPO: The Fission Yeast Phenotype Ontology.\nBioinformatics. 2013 Jul 1;29(13):1671-8. Epub 2013 May 8.\n\nPMID:23658422 DOI:10.1093/bioinformatics/btt266.\n\nSmith RN1, Aleksic J, Butano D, Carr A, Contrino S, Hu F, Lyne M, Lyne R, Kalderimis A, Rutherford K, Stepan R, Sullivan J, Wakeling M, Watkins X, Micklem G.\nInterMine: a flexible data warehouse system for the integration and analysis of heterogeneous biological data.\nBioinformatics. 2012 Dec 1;28(23):3163-5. Epub 2012 Sep 27.\n\nPMID:23023984 DOI:10.1093/bioinformatics/bts577\n\nHoehndorf R, Harris MA, Herre H, Rustici G, Gkoutos GV.\nSemantic integration of physiology phenotypes with an application to the Cellular Phenotype Ontology.\nBioinformatics. 2012 Jul 1;28(13):1783-9. Epub 2012 Apr 26.\n\nPMID:22539675 DOI:10.1093/bioinformatics/bts250\n\nThomas PD, Wood V, Mungall CJ, Lewis SE, Blake JA; Gene Ontology Consortium.- On the Use of Gene Ontology Annotations to Assess Functional Similarity among Orthologs and Paralogs: A Short Report.\nPLoS Comput Biol. 2012;8(2):e1002386. Epub 2012 Feb 16.\n\nPMID:22359495 DOI:10.1371/journal.pcbi.1002386\n\nContrino S, Smith RN, Butano D, Carr A, Hu F, Lyne R, Rutherford K, Kalderimis A, Sullivan J, Carbon S, Kephart ET, Lloyd P, Stinson EO, Washington NL, Perry MD, Ruzanov P, Zha Z, Lewis SE, Stein LD, Micklem G.\nmodMine: flexible access to modENCODE data.\nNucleic Acids Res. 2012 Jan;40(Database issue):D1082-8. Epub 2011 Nov 12.\n\nPMID:22080565 DOI:10.1093/nar/gkr921\n\nWood V, Harris MA, McDowall MD, Rutherford K, Vaughan BW, Staines DM, Aslett M, Lock A, Bähler J, Kersey PJ, Oliver SG.\nPomBase: a comprehensive online resource for fission yeast.\nNucleic Acids Res. 2012 Jan;40(Database issue):D695-9. Epub 2011 Oct 28.\n\nPMID:22039153 DOI:10.1093/nar/gkr853\n\nWood V, Harris MA, McDowall MD, Rutherford K, Vaughan BW, Staines DM, Aslett M, Lock A, Bähler J, Kersey PJ, Oliver SG.\nPomBase: a comprehensive online resource for fission yeast.\nNucleic Acids Res. 2012 Jan;40(Database issue):D695-9. Epub 2011 Oct 28.\n\nPMID:22039153 DOI:10.1093/nar/gkr853\n\nLeonelli S, Diehl AD, Christie KR, Harris MA, Lomax J.\nHow the gene ontology evolves.\nBMC Bioinformatics. 2011 Aug 5;12:325.\n\nPMID:21819553 DOI:10.1186/1471-2105-12-325\n\nBitton DA, Wood V, Scutt PJ, Grallert A, Yates T, Smith DL, Hagan IM, Miller CJ.\nAugmented annotation of the Schizosaccharomyces pombe genome reveals additional genes required for growth and viability.\nGenetics. 2011 Apr;187(4):1207-17. Epub 2011 Jan 26.\n\nPMID:21270388 DOI:10.1534/genetics.110.123497\n\nGene Ontology Consortium\nThe Gene Ontology:enhancements for 2011.\nNucleic Acids Res. 2011 Jan;40(Database issue):D559-64. Epub 2012 Nov 17.\n\nPMID:22102568 DOI:10.1093/nar/gkr1028\n\nKim DU, Hayles J, Kim D, Wood V, Park HO, Won M, Yoo HS, Duhig T, Nam M, Palmer G, Han S, Jeffery L, Baek ST, Lee H, Shim YS, Lee M, Kim L, Heo KS, Noh EJ, Lee AR, Jang YJ, Chung KS, Choi SJ, Park JY, Park Y, Kim HM, Park SK, Park HJ, Kang EJ, Kim HB, Kang HS, Park HM, Kim K, Song K, Song KB, Nurse P, Hoe KL.\nAnalysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.\nNat Biotechnol. 2010 Jun;28(6):617-623. Epub 2010 May 16.\n\nPMID:20473289 DOI:10.1038/nbt.1628\n\nGene Ontology Consortium\nThe Gene Ontology in 2010: extensions and refinements.\nNucleic Acids Res. 2010 Jan;38(Database issue):D331-5. Epub 2009 Nov 17.\n\nPMID:19920128 DOI:10.1093/nar/gkp1018\n\nPreprints\n\nHarris MA, Rutherford KM, Hayles J, Lock A, Bähler J, Oliver SG, Mata J, Wood V.\nFission stories: Using PomBase to understand Schizosaccharomyces pombe biology.\nPre-publication manuscript available at bioRxiv.\nPublished — see above.\n\nWood V, Carbon S, Harris MA, Lock A, Engel SR, Hill DP, Van Auken K, Attrill H, Feuermann M, Gaudet P, Lovering RC, Poux S, Rutherford KM, Mungall CJ.\nTerm Matrix: A novel Gene Ontology annotation quality control system based on ontology term co-annotation patterns.\nPre-publication manuscript available at bioRxiv.\nPublished — see above.\n\nWood V, Lock A, Harris MA, Rutherford K, Bähler J, Oliver SG.\nHidden in plain sight: What remains to be discovered in the eukaryotic proteome?\nPre-publication manuscript available at bioRxiv.\nPublished — see above.\n\nBook chapter\n\nLock A, Rutherford K, Harris MA, Wood V. 2018.\nPomBase: The Scientific Resource for Fission Yeast.\nIn Kollmar M. (ed) Eukaryotic Genomic Databases. Methods in Molecular Biology, vol 1757. Humana Press, New York, NY\n\nDOI:10.1007/978-1-4939-7737-6_4\n\nOther documents\n\nWood, V., Harris, M., Lock, A., & Rutherford, K.\nNew PomBase Website 2017, Group Leader Survey Summary.\nPomBase 2017-12-01\n\n10.17863/CAM.36799\n\nInfographics\n\n2017 PomBase infographic (PDF; file at FTP site)\n\nMore\n\nPosters and slides from conferences and workshops are available on the Documents page.\n\nAltmetric badges link to data provided by Altmetric.com, a research metrics company who track and collect the online conversations around millions of scholarly outputs. Read more about Altmetrics.\n",
+      "content" : "\n\nPlease see the Citing PomBase page, which lists papers to cite for PomBase, the S. pombe genome sequence, Canto, FYPO, annotations and Compara.\n\nJournal articles\n\nManuel Lera-Ramírez, Jürg Bähler, Juan Mata, Kim Rutherford, Charles S Hoffman, Sarah Lambert, Snezhana Oliferenko, Sophie G Martin, Kathleen L Gould, Li-Lin Du, Sarah A Sabatinos, Susan L Forsburg, Olaf Nielsen, Paul Nurse, Valerie Wood\nRevised fission yeast gene and allele nomenclature guidelines for machine readability\nGenetics, September 2023, iyad031\n\n10.1093/genetics/iyad143\n\nAlayne Cuzick, James Seager, Valerie Wood, Martin Urban, Kim Rutherford, Kim E Hammond-Kosack\nA framework for community curation of interspecies interactions literature\neLife, 12:e84658\n\n10.7554/eLife.84658\n\nGene Ontology Consortium.\nThe Gene Ontology knowledgebase in 2023\nGenetics, Volume 224, Issue 1, May 2023, iyad031\n\n10.1093/genetics/iyad031\n\nVivian Monzon, Typhaine Paysan-Lafosse, Valerie Wood, Alex Bateman\nReciprocal Best Structure Hits: Using AlphaFold models to discover distant homologues\nBioinformatics Advances, October 2022, vbac072\n\n10.1093/bioadv/vbac072\n\nValérie de Crécy-lagard et al. (including Val Wood)\nA roadmap for the functional annotation of protein families: a community perspective\nDATABASE, Volume 2022, August 2022, baac062\n\nPMID:35961013 10.1093/database/baac062\n\nValerie Wood, Paul W Sternberg, Howard D Lipshitz\nMaking biological knowledge useful for humans and machines\nGenetics, Volume 220, Issue 4, April 2022, iyac001\n\nPMID:35380659 10.1093/genetics/iyac001\n\nHarris MA, Rutherford KM, Hayles J, Lock A, Bähler J, Oliver S, Mata J, Wood V\nFission stories: Using PomBase to understand Schizosaccharomyces pombe biology\nGenetics, Volume 220, Issue 4, April 2022, iyab222\n\nPMID:35100366 10.1093/genetics/iyab222\n\nRutherford KM, Harris MA, Oliferenko S, Wood V\nJaponicusDB: rapid deployment of a model organism database for an emerging model species\nGenetics, Volume 220, Issue 4, April 2022, iyab223\n\nPMID:35380656 10.1093/genetics/iyab223\n\nUrban M, Cuzick A, Seager J, Wood V, Rutherford K, Venkatesh SY, Sahu J, Vijaylakshmi Iyer S, Khamari L, De Silva N, Martinez MC, Pedro H, Yates AD, Hammond-Kosack KE\nPHI-base in 2022: a multi-species phenotype database for Pathogen–Host Interactions\nNAR, Volume 50, Issue D1, 7 January 2022, Pages D837–D847\n\nPMID:34788826 10.1093/nar/gkab1037\n\nGene Ontology Consortium.\nThe Gene Ontology resource: enriching a GOld mine.\nNucleic Acids Res. 2021 Jan 8;49(D1):D325-D334.\n\nPMID:33290552 DOI:10.1093/nar/gkaa1113\n\nWood V, Carbon S, Harris MA, Lock A, Engel SR, Hill DP, Van Auken K, Attrill H, Feuermann M, Gaudet P, Lovering RC, Poux S, Rutherford KM, Mungall CJ.\nTerm Matrix: a novel Gene Ontology annotation quality control system based on ontology term co-annotation patterns.\nOpen Biol 2020 Sep;10(9):200149\n\nPMID:32875947 DOI:10.1098/rsob.200149\n\nShefchek KA et al. (including Harris MA).\nThe Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species.\nNucleic Acids Res. 2020 Jan 8;48(Database issue): D704-D715.\n\nPMID:31701156 DOI:10.1093/nar/gkz997\n\nUrban M, Cuzick A, Seager J, Wood V, Rutherford K, Venkatesh SY, De Silva N, Martinez MC, Pedro H, Yates AD, Hassani-Pak K, Hammond-Kosack KE.\nPHI-base: the pathogen-host interactions database.\nNucleic Acids Res. 2020 Jan 8;48(Database issue): D613-D620.\n\nPMID:31733065 DOI:10.1093/nar/gkz904\n\nLock A, Harris MA, Rutherford K, Hayles J, Wood V.\nCommunity curation in PomBase: enabling fission yeast experts to provide detailed, standardized, sharable annotation from research publications.\nDatabase (Oxford) 2020 Jan 1;2020. pii: baaa028.\n\nPMID:32353878 DOI:10.1093/database/baaa028\n\nDikicioglu D, Nightingale DJH, Wood V, Lilley KS, Oliver SG.\nTranscriptional regulation of the genes involved in protein metabolism and processing in Saccharomyces cerevisiae.\n* FEMS Yeast Res.* 2019 Mar 1;19(2):foz014.\n\nPMID:30753445 DOI:10.1093/femsyr/foz014\n\nWood V, Lock A, Harris MA, Rutherford K, Bähler J, Oliver SG.\nHidden in plain sight: What remains to be discovered in the eukaryotic proteome?\nOpen Biol 2019 Feb 28;9(2):180241.\n\nPMID:30938578 DOI:10.1098/rsob.180241\n\nThe Gene Ontology Consortium.\nThe Gene Ontology Resource: 20 years and still GOing strong.\nNucleic Acids Res. 2019 Jan 8;47(Database issue):D330-D338.\n\nPMID:30395331 DOI:10.1093/nar/gky1055\n\nThe RNAcentral Consortium.\nRNAcentral: a hub of information for non-coding RNA sequences.\nNucleic Acids Res. 2019 Jan 8;47(Database issue):D221-D229. Epub 2018 Nov 5.\n\nPMID:30395267 DOI:10.1093/nar/gky1034 (Correction in DOI:10.1093/nar/gky1206)\n\nLock A, Rutherford K, Harris MA, Hayles J, Oliver SG, Bähler J; Wood V.\nPomBase 2018: user-driven reimplementation of the fission yeast database provides rapid and intuitive access to diverse, interconnected information.\nNucleic Acids Res. 2019 Jan 8;47(Database issue): D821-D827. Epub 2018 Oct 13.\n\nPMID:30321395 DOI:10.1093/nar/gky961\n\nGene Ontology Consortium.\nAnnotation of gene product function from high-throughput studies using the Gene Ontology.\nDatabase (Oxford). 2019 Jan 1;2019:baz007.\n\nPMID:30715275 DOI:10.1093/database/baz007\n\nUrban M, Cuzick A, Rutherford K, Irvine A, Pedro H, Pant R, Sadanadan V, Khamari L, Billal S, Mohanty S, Hammond-Kosack KE.\nPHI-base: a new interface and further additions for the multi-species pathogen-host interactions database.\nNucleic Acids Res. 2017 Jan 4;45(D1):D604-D610. Epub 2016 Dec 3.\n\nPMID:27915230 DOI:10.1093/nar/gkw1089\n\nThe Gene Ontology Consortium\nExpansion of the Gene Ontology knowledgebase and resources.\nNucleic Acids Res. 2017 Jan 4;45(D1):D331-D338. Epub 2016 Nov 29.\n\nPMID:27899567 DOI:10.1093/nar/gkw1108\n\nThe RNAcentral Consortium\nRNAcentral: a comprehensive database of non-coding RNA sequences.\nNucleic Acids Res. 2017 Jan 4;45(D1):D128-D134. Epub 2016 Oct 28.\n\nPMID:27794554 DOI:10.1093/nar/gkw1008\n\nHuntley RP, Sitnikov D, Orlic-Milacic M, Balakrishnan R, D’Eustachio P, Gillespie ME, Howe D, Kalea AZ, Maegdefessel L, Osumi-Sutherland D, Petri V, Smith JR, Van Auken K, Wood V, Zampetaki A, Mayr M, Lovering RC.\nGuidelines for the functional annotation of microRNAs using the Gene Ontology.\nRNA. 2016 May;22(5):667-76. Epub 2016 Feb 25.\n\nPMID:26917558 DOI:10.1261/rna.055301.115\n\nOliver SG, Lock A, Harris MA, Nurse P, Wood V.\nModel organism databases: essential resources that need the support of both funders and users.\nBMC Biol. 2016 14(1): 49.\n\nPMID:27334346 DOI:10.1186/s12915-016-0276-z\n\nBitton DA, Schubert F, Dey S, Okoniewski M, Smith GC, Khadayate S, Pancaldi V, Wood V, Bähler J.\nAnGeLi: A Tool for the Analysis of Gene Lists from Fission Yeast.\nFront Genet. 2015 Nov 16;6:330. eCollection 2015.\n\nPMID:26635866 DOI:10.3389/fgene.2015.00330\n\nHoffman CS, Wood V, Fantes PA.\nAn Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System.\nGenetics. 2015 Oct;201(2):403-23.\n\nPMID:26447128 DOI:10.1534/genetics.115.181503\n(Erratum in PMID:26953269 DOI:10.1534/genetics.116.187088)\n\nGene Ontology Consortium\nGene Ontology Consortium: going forward.\nNucleic Acids Res. 2015 Jan;43(Database issue):D1049-56. Epub 2014 Nov 26.\n\nPMID:25428369 DOI:10.1093/nar/gku1179\n\nMcDowall MD, Harris MA, Lock A, Rutherford K, Staines DM, Bähler J, Kersey PJ, Oliver SG, Wood V.\nPomBase 2015: updates to the fission yeast database.\nNucleic Acids Res. 2015 Jan;43(Database issue):D665-61. Epub 2014 Oct 31.\n\nPMID:25361970 DOI:10.1093/nar/gku1040\n\nDikicioglu D, Wood V, Rutherford KM, McDowall MD, Oliver SG.\nImproving functional annotation for industrial microbes: a case study with Pichia pastoris.\nTrends Biotechnol. 2014 Aug;32(8):396-9. Epub 2014 Jun 11.\n\nPMID:24929579 DOI:10.1016/j.tibtech.2014.05.003\n\nAlam-Faruque Y, Hill DP, Dimmer EC, Harris MA, Foulger RE, Tweedie S, Attrill H, Howe DG, Thomas SR, Davidson D, Woolf AS, Blake JA, Mungall CJ, O’Donovan C, Apweiler R, Huntley RP.\nRepresenting kidney development using the gene ontology.\nPLoS One. 2014 Jun 18;9(6):e99864. eCollection 2014.\n\nPMID:24941002 DOI:10.1371/journal.pone.0099864\n\nHuntley RP, Harris MA, Alam-Faruque Y, Blake JA, Carbon S, Dietze H, Dimmer EC, Foulger RE, Hill DP, Khodiyar VK, Lock A, Lomax J, Lovering RC, Mutowo-Meullenet P, Sawford T, Van Auken K, Wood V, Mungall CJ.\nA method for increasing expressivity of Gene Ontology annotations using a compositional approach.\nBMC Bioinformatics. 2014 May 21;15:155.\n\nPMID:24885854 DOI:10.1186/1471-2105-15-155.\n\nRutherford KM, Harris MA, Lock A, Oliver SG, Wood V.\nCanto: An online tool for community literature curation.\nBioinformatics. 2014 Jun 15;30(12):1791-2. Epub 2014 Feb 25.\n\nPMID:24574118 DOI:10.1093/bioinformatics/btu103\n\nHill DP, Adams N, Bada M, Batchelor C, Berardini TZ, Dietze H, Drabkin HJ, Ennis M, Foulger RE, Harris MA, Hastings J, Kale NS, de Matos P, Mungall CJ, Owen G, Roncaglia P, Steinbeck C, Turner S, Lomax J.\nDovetailing biology and chemistry: integrating the Gene Ontology with the ChEBI chemical ontology.\nBMC Genomics. 2013 Jul 29;14:513.\n\nPMID:23895341 DOI:10.1186/1471-2164-14-513\n\nBalakrishnan R1, Harris MA, Huntley R, Van Auken K, Cherry JM.\nA guide to best practices for Gene Ontology (GO) manual annotation.\nDatabase (Oxford). 2013 Jul 9;2013:bat054. Print 2013.\n\nPMID:23842463 DOI:10.1093/database/bat054.\n\nHayles J, Wood V, Jeffery L, Hoe KL, Kim DU, Park HO, Salas-Pino S, Heichinger C, Nurse P.\nA genome-wide resource of cell cycle and cell shape genes of fission yeast.\nOpen Biol. 2013 May 22;3(5):130053.\n\nPMID:23697806 DOI:10.1098/rsob.130053\n\nGene Ontology Consortium\nGene Ontology annotations and resources.\nNucleic Acids Res. 2013 Jan;41(Database issue):D530-5. Epub 2012 Nov 17.\n\nPMID:23161678 DOI:10.1093/nar/gks1050\n\nHarris MA, Lock A, Bähler J, Oliver SG, Wood V.\nFYPO: The Fission Yeast Phenotype Ontology.\nBioinformatics. 2013 Jul 1;29(13):1671-8. Epub 2013 May 8.\n\nPMID:23658422 DOI:10.1093/bioinformatics/btt266.\n\nSmith RN1, Aleksic J, Butano D, Carr A, Contrino S, Hu F, Lyne M, Lyne R, Kalderimis A, Rutherford K, Stepan R, Sullivan J, Wakeling M, Watkins X, Micklem G.\nInterMine: a flexible data warehouse system for the integration and analysis of heterogeneous biological data.\nBioinformatics. 2012 Dec 1;28(23):3163-5. Epub 2012 Sep 27.\n\nPMID:23023984 DOI:10.1093/bioinformatics/bts577\n\nHoehndorf R, Harris MA, Herre H, Rustici G, Gkoutos GV.\nSemantic integration of physiology phenotypes with an application to the Cellular Phenotype Ontology.\nBioinformatics. 2012 Jul 1;28(13):1783-9. Epub 2012 Apr 26.\n\nPMID:22539675 DOI:10.1093/bioinformatics/bts250\n\nThomas PD, Wood V, Mungall CJ, Lewis SE, Blake JA; Gene Ontology Consortium.- On the Use of Gene Ontology Annotations to Assess Functional Similarity among Orthologs and Paralogs: A Short Report.\nPLoS Comput Biol. 2012;8(2):e1002386. Epub 2012 Feb 16.\n\nPMID:22359495 DOI:10.1371/journal.pcbi.1002386\n\nContrino S, Smith RN, Butano D, Carr A, Hu F, Lyne R, Rutherford K, Kalderimis A, Sullivan J, Carbon S, Kephart ET, Lloyd P, Stinson EO, Washington NL, Perry MD, Ruzanov P, Zha Z, Lewis SE, Stein LD, Micklem G.\nmodMine: flexible access to modENCODE data.\nNucleic Acids Res. 2012 Jan;40(Database issue):D1082-8. Epub 2011 Nov 12.\n\nPMID:22080565 DOI:10.1093/nar/gkr921\n\nWood V, Harris MA, McDowall MD, Rutherford K, Vaughan BW, Staines DM, Aslett M, Lock A, Bähler J, Kersey PJ, Oliver SG.\nPomBase: a comprehensive online resource for fission yeast.\nNucleic Acids Res. 2012 Jan;40(Database issue):D695-9. Epub 2011 Oct 28.\n\nPMID:22039153 DOI:10.1093/nar/gkr853\n\nWood V, Harris MA, McDowall MD, Rutherford K, Vaughan BW, Staines DM, Aslett M, Lock A, Bähler J, Kersey PJ, Oliver SG.\nPomBase: a comprehensive online resource for fission yeast.\nNucleic Acids Res. 2012 Jan;40(Database issue):D695-9. Epub 2011 Oct 28.\n\nPMID:22039153 DOI:10.1093/nar/gkr853\n\nLeonelli S, Diehl AD, Christie KR, Harris MA, Lomax J.\nHow the gene ontology evolves.\nBMC Bioinformatics. 2011 Aug 5;12:325.\n\nPMID:21819553 DOI:10.1186/1471-2105-12-325\n\nBitton DA, Wood V, Scutt PJ, Grallert A, Yates T, Smith DL, Hagan IM, Miller CJ.\nAugmented annotation of the Schizosaccharomyces pombe genome reveals additional genes required for growth and viability.\nGenetics. 2011 Apr;187(4):1207-17. Epub 2011 Jan 26.\n\nPMID:21270388 DOI:10.1534/genetics.110.123497\n\nGene Ontology Consortium\nThe Gene Ontology:enhancements for 2011.\nNucleic Acids Res. 2011 Jan;40(Database issue):D559-64. Epub 2012 Nov 17.\n\nPMID:22102568 DOI:10.1093/nar/gkr1028\n\nKim DU, Hayles J, Kim D, Wood V, Park HO, Won M, Yoo HS, Duhig T, Nam M, Palmer G, Han S, Jeffery L, Baek ST, Lee H, Shim YS, Lee M, Kim L, Heo KS, Noh EJ, Lee AR, Jang YJ, Chung KS, Choi SJ, Park JY, Park Y, Kim HM, Park SK, Park HJ, Kang EJ, Kim HB, Kang HS, Park HM, Kim K, Song K, Song KB, Nurse P, Hoe KL.\nAnalysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.\nNat Biotechnol. 2010 Jun;28(6):617-623. Epub 2010 May 16.\n\nPMID:20473289 DOI:10.1038/nbt.1628\n\nGene Ontology Consortium\nThe Gene Ontology in 2010: extensions and refinements.\nNucleic Acids Res. 2010 Jan;38(Database issue):D331-5. Epub 2009 Nov 17.\n\nPMID:19920128 DOI:10.1093/nar/gkp1018\n\nPreprints\n\nHarris MA, Rutherford KM, Hayles J, Lock A, Bähler J, Oliver SG, Mata J, Wood V.\nFission stories: Using PomBase to understand Schizosaccharomyces pombe biology.\nPre-publication manuscript available at bioRxiv.\nPublished — see above.\n\nWood V, Carbon S, Harris MA, Lock A, Engel SR, Hill DP, Van Auken K, Attrill H, Feuermann M, Gaudet P, Lovering RC, Poux S, Rutherford KM, Mungall CJ.\nTerm Matrix: A novel Gene Ontology annotation quality control system based on ontology term co-annotation patterns.\nPre-publication manuscript available at bioRxiv.\nPublished — see above.\n\nWood V, Lock A, Harris MA, Rutherford K, Bähler J, Oliver SG.\nHidden in plain sight: What remains to be discovered in the eukaryotic proteome?\nPre-publication manuscript available at bioRxiv.\nPublished — see above.\n\nBook chapter\n\nLock A, Rutherford K, Harris MA, Wood V. 2018.\nPomBase: The Scientific Resource for Fission Yeast.\nIn Kollmar M. (ed) Eukaryotic Genomic Databases. Methods in Molecular Biology, vol 1757. Humana Press, New York, NY\n\nDOI:10.1007/978-1-4939-7737-6_4\n\nOther documents\n\nWood, V., Harris, M., Lock, A., & Rutherford, K.\nNew PomBase Website 2017, Group Leader Survey Summary.\nPomBase 2017-12-01\n\n10.17863/CAM.36799\n\nInfographics\n\n2017 PomBase infographic (PDF; file at FTP site)\n\nMore\n\nPosters and slides from conferences and workshops are available on the Documents page.\n\nAltmetric badges link to data provided by Altmetric.com, a research metrics company who track and collect the online conversations around millions of scholarly outputs. Read more about Altmetrics.\n",
       "heading" : "PomBase and collaborative publications",
       "id" : "about/published-by-pombase"
    },
@@ -1004,6 +1004,11 @@
       "heading" : "What is GO term enrichment? How can I do it for my genes?",
       "id" : "faq/what-go-term-enrichment-how-can-i-do-it-my-genes"
    },
+   {
+      "content" : "\n\nThe URL is: https://www.pombase.org/pombemine/service\n\nThis URL is needed in order to access the PombeMine API programmatically;. See the InterMine web service documentation for details.\n",
+      "heading" : "What is the PombeMine service URL",
+      "id" : "faq/what-pombemine-service-url"
+   },
    {
       "content" : "\n\nPSL is a tab-delimited text format that represents sequence alignments.\n\nPSL format is described in the UCSC Genome Bioinformatics FAQ, and the Broad Institute file format guide provides additional information.\n",
       "heading" : "What is PSL format?",
@@ -2245,7 +2250,12 @@
       "id" : "news/2023-09-20-list-of-publication-genes"
    },
    {
-      "content" : "\n\nAccessing the list of genes from a paper\n\n2023-09-20\n\nIt’s now possible to view the list of genes associated with a paper, using a new link on the publication pages. The gene list can then optionally be sent to the Advanced Search.\n\n[Publication page, highlightling the new genes link]\n\nProtein feature viewer added to gene pages\n\n2023-07-27\n\nPomBase gene pages now include a protein feature widget. This tool shows protein features in the context of amino acid sequence. It includes:\n\n-  amino acid substitution positions\n-  Pfam domains\n-  protein modifications\n-  protein properties: low complexity regions, disordered regions, coiled coil regions and predicted trans-membrane domains\n\nHover over features for more information, such as allele descriptions and Pfam domain IDs.\n\n[Protein feature viewer widget - cdc15 gene page]\n\nFollow the “View all protein features …” link for a detailed view on the dedicated protein features page that includes:\n\n-  details of the individual amino acid substitution allele changes\n-  partial amino acid deletions\n\n[Protein feature viewer details page for cdc15]\n\nThanks to the team at RCSB PDB for providing the Open Source software used to implement this feature.\n\nReaction diagrams on term pages\n\n2023-06-19\n\nWhere available, we now show the reaction diagram from Rhea on GO function term pages. This feature is possible thanks to the great work of Rhea.\n\nSee the GO:0003849 term page for an example.\n\n[]\n\nCuration update - “nonsense mutation” merged into “partial amino acid deletion”\n\n2023-04-26\n\nWe have decided to merge the allele type “nonsense mutation” into “partial amino acid deletion”. This has mainly been driven by the fact that allele types that combine different variants require new types, such as “amino_acid_deletion_and_mutation”, “amino_acid_insertion_and_deletion”, etc. Otherwise, we would have ended up with many more types, and at the gene product level (which is what we describe in PomBase in phenotype interactions), both truncations are equivalent. In the next update, this allele type will not be available in Canto.\n\nIn any case, even if two alleles produce the same truncation, such as ase1-D13* or ase1Δ(13-731), they would still have separate entries in PomBase, and they may have different phenotypes. We are only assigning them the same allele type.\n\nIf for your analysis you need to make a distinction between the two using our allele dataset allele dataset, you can always check the “Allele description” field for the presence of the “*” character to tell whether an allele includes a nonsense mutation.\n\nExperimental structures from PDB on gene pages\n\n2023-02-22\n\nThe experimental protein structures from PDB are now embedded on the PomBase gene pages using Mol*. For example: lsm7/SPCC285.12 gene page\n\nIf you select the “PDB structures” view on a gene page, experimental structures will set as your default. AlphaFold predictions will be shown for genes where an experimental structure are not available.\n\nWe now also display the structures on the associated publication page. For example: PMID:31010807 Garg et al.\n\nTo help locate proteins with experimental protein structures (currently 375), we have added a new query option to the “Advanced search”, currently under “commonly used queries”: “Proteins with PDB structures”\n\n[PDB structures on the lsm7 gene page]\n\nAlphaFold protein structure on gene pages\n\n2023-02-02\n\nAlphaFold protein structure are now embedded on the PomBase gene pages. We hope to embed the experimental structures from PDB in the near future.\n\n[Example from the mvp1 gene page]\n\nRevised canonical 5’ UTRs\n\n2023-01-24\n\nWe have revised the curated 5’UTRs using Transcription Start Sites (TSS) data (in vegetative growth/ minimal media) from the Cap Analysis of Gene Expression (CAGE) data provided by Thodberg et al. All new gene structures were manually reviewed, around ~80 protein features had N-terminal coordinate revisions to align with TSS data.\n\nGlobal Core Biodata Resource status for PomBase\n\n2022-12-15\n\nWe are very pleased to announce that PomBase has been selected as one of the first Global Core Biodata Resource (GCBR) — a collection of 37 resources whose long term funding and sustainability is critical to life science and biomedical research worldwide. This accreditation recognizes PomBase as a primary knowledge base (adding value to data through expert curation) and as a crucial component of the research ecosystem. The candidate biodata resources were assessed against a series of rigorous criteria that included their scientific focus, the size and reach of their user communities, their quality of service, their governance, and their impact on global research.\n\nThank you to the entire community, especially the community curators who contribute regularly to our content, and our Scientific Advisory Board for their help and support.\n\nFor more information about the Global Biodata Coalition and PomBase’s new status, see the full press release.\n\nNext PombeTalks: Wednesday, December 14th\n\n2022-12-08\n\nThe next online PombeTalks will take place on Wednesday, December 14th. These talks are virtual seminars by and for the fission yeast community and friends.\n\n8:00 San Francisco; 11:00 NY; 16:00 London; 17:00 Paris; 20:30 Delhi, 23:00 Beijing; midnight Tokyo\n\nThis will be our last PombeTalks of 2022 before taking a winter break. The speaker will be:\n\n-  Kristi E. Miller\n “The fission yeast cell size control system integrates pathways measuring cell surface area, volume and time”\n\nIt will be followed by some sum up/ feedback about PombeTalks from the organizing committee.\n\nSurvey\n\nPlease help us improve PombeTalks even more by taking this quick survey\n\nZoom details\n\nTopic: PombeTalksS308 Zoom Meeting\nDate: Dec 14th\nMeeting ID: 975 0331 6190\nPassword: will be sent the day of the meeting\n\nSlack\n\nFor more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nQuerying by RNA length in the Advanced Search tool\n\n2022-12-07\n\nYou can now query the RNA length of genes (spliced or unspliced) under the “Transcripts and exons” query grouping in the Advanced search.\n\nYou can also add RNA sequence length as a field in tables downloaded from the query builder.\n\n[RNA length queries are available under the “Transcripts and exons” tab]\n\nGenetic Interaction annotation model updated\n\n2022-11-29\n\nWe have recently implemented an improved way to annotate and display genetic interactions so they are linked to phenotype annotations and alleles.\n\nPreviously, our Genetic Interaction annotations only mentioned the interacting genes and the type of genetic interaction. For example, if a strain with genotype asp1-H397A has the phenotype decreased acid phosphatase activity affecting activity of pho1, but this phenotype is suppressed when rhn1 is deleted in that strain, we would annotate that the genes asp1 and rhn1 are part of a Phenotypic Suppression interaction.\n\n[GI old format]\n\nWe continue to display interactions in this format by default (showing only genes and interaction type), but if you expand the annotation, you can view the associated genotypes and phenotypes.\n\n[GI new format]\n\nIn the revised Canto interface, you can only annotate a genetic interaction from the double mutant phenotype annotation (by clicking on add.., as shown below).\n\n[GI annotation in Canto]\n\nOf course, genetic interactions predating this update are not linked to phenotypes or genotypes, but we are hoping to auto-annotate several of those. We will also prioritise for update any interactions where community curators have provided these details in an annotation comment. Finally, a big shoutout to Ana Sanchez and Angad Garg from the Shuman lab, for testing the new interface in numerous recently curated publications. The examples provided here are from Sanchez et al. 2019. Go read it and see the annotations in PomBase.\n\nBest, The PomBase team\n\nNext pombeTalks: Wednesday, November 16th\n\n2022-11-11\n\nThe next online pombeTalks will take place on Wednesday, November 16th. These talks are virtual seminars by and for the fission yeast community and friends.\n\nNote that this session will happen earlier at:\nmidnight San Francisco; 03:00 NY; 08:00 London; 09:00 Paris; 13:30 Delhi, 16:00 Beijing; 17:00 Tokyo\n\nTalks this session:\n\n-  Wenfan Wei, University of Science and Technology of China\n “The Cdc42 GAP Rga6 promotes monopolar outgrowth of spores”\n\n-  Gaowen Liu, Shenzhen Institute of Synthetic Biology\n “Fusion eciency evolution to the deletion of an essential mating gene Prm1”\n\nZoom details\n\nTopic: PombeTalks S03E07 Zoom Meeting\nDate: Nov 16, 2022\nTime: midnight San Francisco; 03:00 NY; 08:00 London; 09:00 Paris; 13:30 Delhi, 16:00 Beijing; 17:00 Tokyo\nMeeting ID: 932 8857 4852\nPassword: will be sent the day of the meeting\n\nSlack\n\nFor more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nUsing AlphaFold models to discover distant human and budding yeast homologues\n\n2022-10-14\n\nWe collaborated with the Pfam group at the EBI to evaluate predictions generated from AlphaFold reciprocal best structure hits to identify potential distant orthologs. The Reciprocal Best Structure Hits (RBSH) approach provided 11 novel human homologues, including Pho86 -> NAT8 (ER acetyltransferase), Mug174 -> COIL (Coilin), Ach1 -> OXCT1 (succinyl-CoA:3-ketoacid coenzyme A transferase), SPAC1952.08c -> CREG1, imt1 -> A4GALT (Lactosylceramide 4-alpha-galactosyltransferase), Rtc5 -> MEAK7 (MTOR associated protein). A further 41 novel orthologs were predicted between S. pombe and S. cerevisiae which had fallen under the radar for all other methods used at PomBase. Most of the novel connections provided additional functional information, or supported existing knowledge for poorly characterised proteins. See supporting data tables S4 and S5 for the complete list of predictions included in PomBase. Article.\n\nNext pombeTalks: Wednesday, October 19th\n\n2022-10-13\n\nThe next online pombeTalks will take place on Wednesday, October 19th. These talks are virtual seminars by and for the fission yeast community and friends.\n\n8:00 San Francisco / 11:00 NY / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / midnight Tokyo\n\nTalks this session:\n\n-  Cecilia D’Alessio, University of Buenos Aires and CONICET\n “N-Glycosylation and glycoprotein folding in fission yeasts, a model to study human congenital disorders of glycosylation”\n\n-  Jason Tanny, McGill University, Montreal\n “A novel transcriptional mechanism regulating the cellular response to replication stress”\n\nZoom details\n\nTopic: PombeTalks S03E06 Zoom Meeting\nTime: Oct 19, 2022 05:00 PM Paris\nMeeting ID: 933 7072 6178\nPassword: will be sent the day of the meeting\n\nSlack\n\nFor more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nNew to fission yeast? check out our quick start guide for new users\n\n2022-10-13\n\nWe have added a new page providing useful information for new fission yeast researchers:\nGetting started with S.pombe and PomBase\n\nIncludes details of how to join the community mailing list and the Slack channel, links to useful tools and resources, information about fission yeast as a model organism, an overview of PomBase and more.\n\n77 new disease gene associations\n\n2022-09-16\n\nWe have added 77 new disease-gene associations for 71 fission yeast human gene orthologs. These were identified using “PombeMine” to identify the disease genes curated by OMIM not annotated with an existing MONDO mapping. The number of human disease gene associations is currently 1471. Disease genes can be browsed via the disease slim set or from the MONDO root node term.\n\nPombeMine: an InterMine instance for S. pombe\n\n2022-09-16\n\nAs part of an Elixir funded collaboration with the InterMine team we have created PombeMine. Gene lists can be sent directly from PomBase query results pages directly to Intermine (under the “export” tab), providing direct (2 click) access to GO and phenotype enrichment tools.\n\nNext pombeTalks: Wednesday, September 21st\n\n2022-09-15\n\nThe next online pombeTalks will take place on Wednesday, September 21st. These talks are virtual seminars by and for the fission yeast community and friends.\n\n8:00 San Francisco / 11:00 NY / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / midnight Tokyo\n\nTalks this session:\n\n-  Manuel Lera Ramirez, PomBase / Tran Lab, Institute Curie “Microtubule rescue at midzone edges promotes overlap stability and prevents spindle collapse during anaphase B”\n\n-  Hannah Opalko, Moseley lab, Dartmouth College “Mechanisms of spatial patterning of cell cycle regulator Cdr2”\n\nZoom details\n\nTopic: PombeTalks S03E05 Zoom Meeting\nTime: Sep 21, 2022 05:00 PM Paris\nMeeting ID: 985 8572 1420\nPassword: will be sent the day of the meeting\n\nSlack\n\nFor more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nProtein sequence changes\n\n2022-09-06\n\n78 protein have been shortened (at the N-term). This set includes 34 published proteins (Apl4, Brc1, Cdc48, Cdt1, Cho1, Cmb1, Cut2, Cut6, Cwf26, Dbr1, Dri1, Elo2, Eri1, Lsd2, Lys2, Med13, Naa38, Nup107, Nup82, Orc2, Pof10, Ppt1, Rec24, Rga2, Rmt3, Rns1, RRpn7, Sap145, Skb1, Snf5, Snt2, Spn3, Tpp2, Trm1, and Tup12). Allele description changes and modification position changes are pending.\n\nNext pombeTalks: Wednesday, August 17th\n\n2022-08-13\n\nThe next online pombeTalks will take place on Wednesday, August 17th. These talks are virtual seminars by and for the fission yeast community and friends.\n\n8:00 San Francisco / 11:00 NY / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / midnight Tokyo\n\nTalks this session:\n\n-  Pranas Grigaitis, Vrije Universiteit Amsterdam\n “Prediction of metabolic strategies in Schizosaccharomyces pombe based on optimal resource allocation”\n-  Abhishek Poddar, University of Toledo\n “Membrane stretching activates calcium-permeability of a putative channel Pkd2 during fission yeast cytokinesis”\n\nAs always, connection details will be sent the day of the talk. For more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nNext pombeTalks: Wednesday, July 20th\n\n2022-07-12\n\nThe next online pombeTalks will take place on Wednesday, July 20th. These talks are virtual seminars by and for the fission yeast community and friends.\n\n0:00 San Francisco / 3:00 New York / 8:00 London / 9:00 Paris / 12:30 Delhi / 15:00 Beijing / 16:00 Tokyo.\n\nTalks this session:\n\n-  Leeba Ann Chacko, Ananthanarayanan Lab, University of New South Wales\n “Microtubules and mitochondria cooperate to ensure cell division symmetry, polarity and equipartitioning in fission yeast”\n-  Dan Zhang, Temasek Life Sciences Laboratory, National University of Singapore\n “The cortical ER remodeling for actomyosin ring assembly”\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and pombeSlack one day in advance, so make sure you’ve signed up.\n\nPombeTalks Wednesday June 15th\n\n2022-06-14\n\nThe next online pombeTalks will take place on Wednesday June 15th. These are virtual seminars by and for the fission yeast community and friends.\n\n08:00 San Francisco / 11:00 New York / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / 00:00 Tokyo\n\nTalks this session:\n\n-  Elliott Chapman, Bayne Lab, University of Edinburgh\n “Separable roles for RNAi in regulation of transposable elements and viability in the fission yeast Schizosaccharomyces japonicus”\n-  Fei Li, New York University\n “Phosphorylation-mediated Ccp1-Ndc80 switch at the N-terminus of CENP-T regulates kinetochore assembly in fission yeast”\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and pombeSlack one day in advance, so make sure you’ve signed up.\n\nAs before, questions will be posted to #pombetalks-qna on pombeSlack channel and recordings uploaded.\n\nPombeTalks May 18th\n\n2022-05-05\n\nThe next online pombeTalks will take place on May 18th. These are virtual seminars by and for the fission yeast community and friends.\n\n08:00 San Francisco / 11:00 New York / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / 00:00 Tokyo\n\nTalks this session:\n\n-  Jennifer Porat, Bayfield Lab, York University: The methyl phosphate capping enzyme Bmc1/Bin3 is a stable component of the fission yeast telomerase holoenzyme\n-  Ingrid Billault-Chaumartin, Martin Lab, UNIL: Fus1, the fusion focus formin\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nNew phenotype slim\n\n2022-04-13\n\nWe have added a phenotype slim overview to complement those provided for disease association, biological process, molecular function and cellular component annotation. The purpose of the phenotype slim is to provide subsets of commonly used ‘broad’ phenotypic classes or annotation subsets that can provide a useful starting point for accessing phenotype lists. The phenotype slim page provides links to ontology term pages, annotated genes, and to download files containing the slim terms and IDs.\n\nThe phenotype slim has also been added to the PomBase advanced search results panel “Slim with” menu. For example, you can query for all genes involved in a GO process, another phenotype, or any other list, and “slim” the results using the “Phenotype slim” option to view categories of phenotypes assigned to the list.\n\nMaking biological knowledge useful for humans and machines\n\n2022-04-04\n\nA GENETICS special issue featuring model organism database updates is published today. This issue features the recent PomBase and JaponicusDB publications and is accompanied by an editorial “Making biological knowledge useful for humans and machines” co-authored by Val Wood, Paul Sternberg and Howard Lipshitz.\n\n-  Fission stories: using PomBase to understand Schizosaccharomyces pombe biology\n-  JaponicusDB: rapid deployment of a model organism database for an emerging model species\n\nThe fission yeast community have now curated over 1000 publications\n\n2022-03-26\n\nWe would like to extend a huge “thank you” to the fission yeast community for curation contributions. The community have now curated 1008 publications providing 19,156 independent annotations, representing 25% of the curation from small-scale publications. In addition, another 80,000 annotations have been provided via the submission of HTP datasets.\n\nPlease contact us via the helpdesk if you would like to provide curation for your manuscript but don’t know how.\n\nLinks:\n\n-  All community curated publications\n-  Spotlights\n-  Canto curation tool\n-  HTP data and browser track submission\n\nNew human orthologs including 3 MRP complex subunits\n\n2022-03-23\n\nWe continue to identify distant human orthologs. Four new 1:1 human ortholog connections have been added to PomBase this week:\n\n-  RNase MRP subunit Rmp1 = human NEPRO (family submitted to Pfam)\n-  RNase P and RNase MRP subunit Pop23 = human RPP38 (members of the same Pfam clan)\n-  RNase P and RNase MRP subunit Pop8 = human RPP14 (family submitted to Pfam)\n-  glutamyl-tRNA amidotransferase complex subunit 3 (Gtf1) = human GATC\n\nHuman NEPRO is a poorly characterised protein linked to the disease Anauxetic dysplasia 3, and GATC is the causal gene for “combined oxidative phosphorylation deficiency 42”\n\nPomBase now uses InterPro Version 88.0\n\n2022-03-12\n\nPomBase now uses InterPro Version 88.0.\n\nFeatures include:\n\n-  The addition of 39 InterPro entries (40,071 total entries)\n-  Integration of 45 new methods from the PRINTS (1), SMART (1), Pfam (2), SUPERFAMILY (7), CATH-Gene3D (14), PANTHER (13), CDD (7) databases\n\nTOR and nutritional phosphoproteome dataset loaded\n\n2022-03-11\n\nWe have loaded the TOR and nutritional phosphoproteome dataset described in Halova et al. (9424 annotations). Many thanks to Janni Petersen for preparing the files.\n\nPublication page for PMID:33823663\n\nAn additional 5775 novel curated lncRNAs from Atkinson et al.\n\n2022-03-10\n\nWe have added an additional 5775 novel curated lncRNAs from Atkinson et al. to PomBase. We will refine the descriptions of these gene products to align with Sequence Ontology (SO) terms describing RNA features in the coming months.\n\nThanks to María Rodríguez-López for preparing the files.\n\nPublication page for PMID:29914874\n\nPomBase & JaponicusDB publications in the GENETICS MOD reports special issue\n\n2022-02-02\n\nPapers describing PomBase and JaponicusDB are now published (early online). These articles are part of a special issue of GENETICS devoted to model organism database (MOD) reports. The MOD papers will highlight the journal’s new section on Computational Resources, Software & Databases.\n\n-  Fission stories: using PomBase to understand Schizosaccharomyces pombe biology\n-  JaponicusDB: rapid deployment of a model organism database for an emerging model species\n\nImproved options for filtering annotations by cell cycle phase\n\n2021-12-19\n\nThe Gene Ontology annotation filter for “during” specific cell cycle phases is now included on the “Summary” view in addition to the “Details” view. Available phases have been extended to cover all phases used, and to provide\nuseful grouping terms. This filter is “ontology aware” (i.e. a search on interphase will also display G1/S/G2 phase annotation). The phase filter is most useful on pages that display increasing volume of phase-specific curation (such as cdc2). The revised phase filter options are also available in the gene expression section.\n\nThe phase filters are located at the top right of GO and gene expression annotation sections:\n\n[During filter]\n\nPomBase now uses InterPro Version 87.0\n\n2021-11-23\n\nPomBase now uses InterPro Version 87.0, which integrates:\n\n-  1,155 new InterPro entries\n-  Update to Pfam 34.0\n-  1,256 new methods\n\nCoils, disorder, and more: new protein feature queries\n\n2021-10-18\n\nThe PomBase advanced search now allows you to find proteins that have coiled-coil regions, disordered regions, and low-complexity regions. The query-building interface also now organises query options more sensibly, and the documentation has been updated.\n\nPomBase & JaponicusDB preprints\n\n2021-09-27\n\nPapers describing PomBase and JaponicusDB will appear in an issue of GENETICS devoted to model organism database (MOD) reports. The MOD papers will highlight the journal’s new section on Computational Resources, Software & Databases.\n\nFollow the links to the PomBase preprint and JaponicusDB preprint, and watch for the full-fledged publications to appear in March 2022.\n\nJaponicusDB: a new fission yeast database\n\n2021-09-01\n\nWe are delighted to announce the official release of PomBase’s new sister: JaponicusDB is a new, curated model organism database for the fission yeast Schizosaccharomyces japonicus. JaponicusDB highlights include revised gene structures, distant ortholog detection, improved GO annotation, community literature curation, and reciprocal gene page links with PomBase, providing a familiar environment for all fission yeast researchers.\n\nThe S. japonicus community will maintain JaponicusDB from now on. Join the new mailing list, and follow @japonicusdb on Twitter.\n\nImproved gene-disease curation: over 1400 S. pombe genes\n\n2021-08-06\n\nPomBase disease gene curation associates disease descriptors with fission yeast orthologs of human disease-causing genes. We have added new gene–disease term connections, to bring the total to 1401 S. pombe genes. Disease associations now cover 27.3% of all fission yeast protein-coding genes, and almost 40% with human orthologs.\n\nPombeTalks August 4th\n\n2021-07-28\n\nThe next online PombeTalks will take place on Wednesday 4th August 2021, at 17:00 Central European Time. Speakers:\n\n-  Tiffany Mak, Nurse lab, The Francis Crick Institute: The TOR-dependant phosphoproteome and regulation of cellular protein synthesis\n\n-  Weifang Wu, Allshire lab, University of Edinburgh: Spatial organisation of the nucleus influences centromere identity\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nAfter these talks, PombeTalks will take a break for the rest of the summer, so watch this space, pombelist, or PombeSlack for updates. In the meantime, you can fill out this form at any time if you’re interested in speaking.\n\nAlphaFold links\n\n2021-07-28\n\nPomBase gene pages now have links to the AlphaFold Protein Structure Database, the collection of structures predicted by AI developed by DeepMind, hosted at EBI. Look in the “External references” section of your favorite gene page, or check out this example (pap1), or read more at the EBI AlphaFold home.\n\nPombeTalks July 21st\n\n2021-07-14\n\nThe next online PombeTalks will take place on Wednesday 21st July 2021, at 10:00 Central European Time / 17:00 Japan & Korea. Speakers:\n\n-  Yoko Otsubo, Yamashita lab, National Institute for Basic Biology: Novel links between TORC1 and traditional non-coding RNA, tRNA\n\n-  Jie Su, Nakagawa lab, Osaka University: Rad8-dependent PCNA ubiquitination at lysine 107 causes gross chromosomal rearrangements\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nKEGG pathway links\n\n2021-07-06\n\nPomBase gene pages now have links to pathway entries in the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, as well as links to gene lists for each linked pathway (example: 2-Oxocarboxylic acid metabolism). The KEGG pathway links are the first entry in a new gene page section, “Molecular pathway”, dedicated to connecting genes in PomBase to depictions of biochemical and signaling pathways.\n\nPomBase now uses InterPro Version 86.0\n\n2021-06-30\n\nPomBase now uses InterPro Version 86.0, which integrates:\n\n-  299 new InterPro entries\n-  An update to PROSITE patterns [2021_01] and PROSITE profiles [2021_01]\n-  454 new methods from the PROSITE profiles (39), SMART (2), Pfam (7), SUPERFAMILY (3), CATH-Gene3D (80), PANTHER (295), CDD (27), SFLD (1) databases.\n\nInterPro cites 52235 publications in PubMed. See the InterPro release notes for further information.\n\nPombeTalks July 7th\n\n2021-06-30\n\nThe next online PombeTalks will take place on Wednesday 7th July 2021, at 17:00 Central European Time. Speakers:\n\n-  Debatrayee Sinha, Qian Chen lab, University of Toledo: Fission yeast polycystin Pkd2p promotes resumption of cell growth after cytokinesis\n\n-  Joël Lemière, Fred Chang Lab, UCSF: The role of osmotic forces in nuclear size control\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks June 23rd\n\n2021-06-17\n\nThe next online PombeTalks will take place on Wednesday 23rd June 2021, at 17:00 Central European Time. Speakers:\n\n-  Yi Wei, Grewal lab, NCI CCR, Bethesda: TOR targets an RNA processing network to regulate cell proliferation and sexual development\n\n-  Nicholas Ader, LusKing Lab, Yale School of Medicine: I open at the close(d mitosis): Investigating post-mitotic nuclear envelope sealing in fission yeast\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nViolin plots for gene expression\n\n2021-06-15\n\nThe “Quantitative gene expression” section of PomBase gene pages now offers a display of violin plots to visualize where the gene appears in available expression datasets.\n\nViolin plots are also available to visualize sets of up to 150 genes in the advanced search results.\n\nAt present data from Marguerat S et al. (2012) and Carpy A et al. (2014) are included.\n\nPombeTalks June 9th\n\n2021-06-02\n\nThe next online PombeTalks will take place on Wednesday 9th June 2021, at 10:00 Central European Time / 17:00 Japan & Korea. Speakers:\n\n-  Yusuke Toyoda, Saitoh lab, Kurume University: Nitrogen-dependent persistence of S. pombe Ght5 glucose transporter on the cell surface is effected by TORC2 inhibition of α-arrestin Aly3\n\n-  Anupa T. Anil, Mishra lab, IISER Mohali: How does spliceosome capture branchpoint-distant 3’ splice site?\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks May 26th\n\n2021-05-20\n\nThe next online PombeTalks will take place on Wednesday 26th May 2021, at 17:00 Central European Time. Speakers:\n\n-  Mélina Vaurs (Vincent Géli & Stéphane Coulon labs - Cancer Research Center, Marseille): Shelterin-dependent telomerase regulation differs between quiescent and vegetative cells\n\n-  Arthur Molines (Fred Chang lab – UCSF): Physical properties of the cytoplasm modulate microtubule dynamics\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks May 12th\n\n2021-05-05\n\nThe next online PombeTalks will take place on Wednesday 12th May 2021, at 17:00 Central European Time. Speakers:\n\n-  Sierra Cullati, Gould lab, Vanderbilt University: Autophosphorylation of the CK1 Kinase Domain Regulates Enzyme Activity and Substrate Specificity\n\n-  Stephen Huisman, Brunner Lab, University of Zurich: Vip1, a temperature-dependent filament forming protein involved in cell length regulation\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nNew diploid genotype & phenotype display\n\n2021-04-29\n\nPomBase now includes pages for curated diploid genotypes, and displays phenotypes annotated to them on gene and publication pages. For more details see the documentation for phenotype annotations and genotype pages.\n\nPombeTalks April 28th\n\n2021-04-22\n\nThe next online PombeTalks will take place on Wednesday 28th April 2021, at 10:00 Central European Time / 17:00 Japan & Korea. Speakers:\n\n-  Tomoyuki Fukuda, Niigata University Graduate School of Medical and Dental Sciences: Atg43 serves as a selective autophagy receptor to promote mitophagy\n\n-  Xiao-Ran Zhang, NIBS, Beijing, China: An improved auxin-inducible degron system for fission yeast\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPomBase now uses InterPro Version 85.0\n\n2021-04-15\n\nPomBase now uses InterPro Version 85.0, which integrates:\n\n-  157 new InterPro entries\n-  An update to CATH-Gene3D [4.3.0]\n-  333 new methods from the Pfam (3), SUPERFAMILY (11), CATH-Gene3D (168), PANTHER (88), CDD (62), SFLD (1) databases\n\nInterPro cites 51539 publications in PubMed. See the InterPro release notes for further information.\n\nPombeTalks April 14th\n\n2021-04-08\n\nThe next online PombeTalks will take place on Wednesday 14th April 2021, at 17:00 Central European Time:\n\n-  Pabitra Parua,�Fisher�lab,�Icahn School of Medicine at Mount Sinai: Control of the RNA polymerase II transcription cycle by CDK-phosphatase switches\n\n-  Ye Dee Tay, Sawin Lab,�University of�Edinburgh: Gef1: the first aider of Cdc42 polarity module during stress\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the new Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nNew genome browser data: GC content\n\n2021-03-31\n\nA data track showing the fraction of G/C bases in a region is now available in PomBase JBrowse, listed under “Base composition”. The track is generated using the gccontent plugin, and uses a default window of 100 bp.\n\nQualitative gene expression annotation in Canto\n\n2021-03-31\n\nCanto, PomBase’s online curation tool, now supports qualitative gene expression annotation. Two new annotation types are available to represent observations about the levels of RNA or protein observed in wild-type cells, and how they change over the cell cycle or in response to a stimulus. See the Canto documentation for more information. We have also updated the display of qualitative gene expression on PomBase gene and publication pages.\n\nNew protein feature display\n\n2021-03-30\n\nPomBase has released a new, interactive display for protein features on gene pages. The new view is clearer, with details for each feature available via mouseover as well as in the accompanying table.\n\nIn addition, PomBase now uses InterPro Version 84.0, which includes 205 new entries and integrates 252 new methods from the Pfam, PANTHER, and CDD databases. See the InterPro release notes for further information.\n\nPombeTalks March 31st\n\n2021-03-27\n\nThe next online PombeTalks will take place on Wednesday 31st March 2021, at 17:00 Central European Time:\n\n-  Udo Onwubiko, Das lab, University of Tennessee: Cdc42 prevents early Rho1 activation during cytokinesis\n\n-  Chunmin Shan, Jia lab, Columbia University: The INO80 complex regulates epigenetic inheritance of heterochromatin\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the new Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks March 17th - new time!\n\n2021-03-10\n\nThe new season of online PombeTalks for 2021 will begin on Wednesday 3rd March 2021, at a different time: 9:00 Central European Time / 17:00 Japan & Korea. Speakers:\n\n-  Yasuto Murayama, National Institute of Genetics, Shizuoka: Biochemical analysis of the fission yeast structural maintenance of chromosomes complex\n\n-  Ken Ishikawa, Kurume University, Kurume: dCas9-mediated CRISPRi for S. pombe\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the new Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks return March 3rd\n\n2021-02-24\n\nThe new season of online PombeTalks for 2021 will begin on Wednesday 3rd March 2021 at 17:00 Central European Time:\n\n-  Maria Rodriguez Lopez, Bähler lab, UCL: Clr6 orchestrates transcriptional switches to regulate metabolism during oxidative stress\n\n-  Olivia Muriel-Lopez, Martin lab, University of Lausanne: ’Ultrastructural plasma membrane asymmetries underlie cell-cell fusion in S. pombe*\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will resume its fortnightly schedule, so watch this space, pombelist, or PombeSlack for updates. As in the past, you are always welcome to fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPomBase identifier mapper now available\n\n2021-02-04\n\nWe have developed an identifier mapper that retrieves S. pombe gene systematic IDs and standard names for a selection of different input ID types. You can now find S. pombe genes using UniProt accessions, and retrieve manually curated orthologs for S. cerevisiae using standard gene names or ORF names, and for human using standard gene names or HGNC identifiers.\n\nTry the identifier mapper or check out the documentation.\n\nPomBase now uses InterPro Version 83.0\n\n2021-01-25\n\nPomBase now uses InterPro Version 83.0, which integrates:\n\n-  376 new InterPro entries\n-  An update to HAMAP [2020_05], CDD [3.18]\n-  462 new methods from the SMART (2), TIGRFAMs (2), Pfam (3), PANTHER (140), HAMAP (19), CDD (286), SFLD (10) databases\n\nInterPro cites 50487 publications in PubMed. See the InterPro release notes for further information.\n\nFirst S. pombe microPublication goes live\n\n2021-01-07\n\nThe first fission yeast microPublication has now been published:\n\nNafees Ahamad, Simmi Anjum, Shakil Ahmed\\ Pyrogallol induces oxidative stress defects in the fission yeast S. pombe.\n\nCongratulations to the authors, and thanks to the microPublication team!\n\nPombeTalks November 25th\n\n2020-11-18\n\nThe last online PombeTalks for 2020 will take place on Wednesday 25th November 2020 at 17:00 Central European Time:\n\n-  I-Ju Lee, David Pellman’s Lab, Dana-Farber Cancer Institute: Factors promoting nuclear envelope assembly independent of the canonical ESCRT pathway\n\n-  Ulrike Endesfelder, Carnegie Mellon University: TBC\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nAfter these talks, PombeTalks will take a well-earned break, and return in early 2021. The schedule is available, and you are always welcome to fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks November 11th\n\n2020-11-04\n\nThe next online PombeTalks will take place on Wednesday 11th November 2020 at 17:00 Central European Time:\n\n-  Farnaz Mansouri, Mark Bayfield lab (York University, Toronto): The uncharacterized S. pombe La-related protein 1 functions in translation and affects RNA abundance\n\n-  Saz Basu, Paul Nurse lab (Francis Crick Institute, London): Unmasking the mitotic potential of G1/S Cyclin-CDK\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on November 25. PombeTalks will then take a break, and return in early 2021. The schedule is available, and you are always welcome to fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nGO annotations from PAINT\n\n2020-11-01\n\nPomBase now includes over 3000 GO annotations made using Phylogenetic Annotation and INference Tool (PAINT), developed by the GO Consortium to infer protein function in a phylogenetic context, supporting precise assertions as to when functions were gained and lost during evolution. PAINT annotations use the evidence code “inferred from biological aspect of ancestor” (IBA). PAINT curation is described in more detail in Gaudet et al. 2011.\n\nPombeTalks October 28th\n\n2020-10-24\n\nThe next online PombeTalks will take place on Wednesday 28th October 2020 at 17:00 Central European Time:\n\n-  Omaya Dudin, EPFL, Switzerland: Cellularization of Ichthyosporean coenocytes\n\n-  Bassem Al-Sady, UCSF, USA: Single cell analysis of the heterochromatin spreading reaction\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on November 11, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks October 14th\n\n2020-10-08\n\nThe next online PombeTalks will take place on Wednesday 14th October 2020 at 17:00 Central European Time:\n\n-  Dimitrios Vavylonis, Lehigh University: Modeling fission yeast’s polarization pattern\n\n-  Chloe Snider, Gould Lab, Vanderbilt University: Opposite surfaces of the Cdc15 F-BAR domain create a membrane platform that coordinates cytoskeletal and signaling components for cytokinesis\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on October 28, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks September 30th\n\n2020-09-23\n\nThe next online PombeTalks will take place on Wednesday 16th September 2020 at 17:00 Central European Time:\n\n-  Alexander Lorenz, University of Aberdeen, UK: Meiotic recombination outcome in the face of genetic diversity\n\n-  Veneta Gerganova, Martin Lab, UNIL, Switzerland: Patterning of membrane-associated proteins through membrane flows\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on October 14, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nNew genome browser datasets 2020-09-17\n\n2020-09-17\n\nTwo new datasets in are now available in PomBase JBrowse (links go to PomBase publication pages, which in turn link to the browser with the tracks enabled):\n\n-  Meiotic DSBs from\n Fowler KR, Gutiérrez-Velasco S, Martín-Castellanos C, Smith GR. 2013.\n Protein determinants of meiotic DNA break hot spots.\n PMID:25747261 DOI: 10.1016/j.molcel.2013.01.008\n\nand\n\n-  Time-lapse single-cell transcripts for dormancy breaking from\n Tsuyuzaki H, Hosokawa M, Arikawa K, Yoda T, Okada N, Takeyama H, Sato. 2020.\n Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast.\n PMID:32152323 DOI: 10.1016/j.molcel.2013.01.008\n\nMore datasets are always welcome, so check out our instructions for submission.\n\nPombeTalks September 16th\n\n2020-09-14\n\nThe next online PombeTalks will take place on Wednesday 16th September 2020 at 17:00 Central European Time:\n\n-  Susan Forsburg, University of Southern California: Visualizing replication stress\n\n-  Sigurd Braun, Ludwig-Maximilians-Universität, München: Gene repression at the nuclear membrane: Multifaceted roles of Lem2\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on September 30, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nNew dataset: Hermes transposon insertions\n\n2020-09-11\n\nPomBase now hosts transposon integration data from Lee et al. 2020. Henry Levin explains the background and significance of the work:\n\n“Transposon Integration Sequencing is a genome wide method of mapping sequences that contribute to growth. High throughput sequencing of transposon integration sites in haploid cells with single insertions reveals which genes are dispensable. Once propagated, cultures exhibit a pronounced lack of insertions in genes necessary for growth. This method, originally developed to study bacteria is now used to characterize the genomes of several yeasts including S. pombe. In earlier work we used the transposon Hermes to identify genes of S. pombe required for growth (Guo et al., 2013, Genetics, PMID:23893486). We have now applied Hermes and Transposon Integration Sequencing to identify genes important for the formation of heterochromatin (Lee et al., 2020, Cell Reports, PMID:32101745). Insertion sites from eight independent cultures can be visualized from PomBase as custom tracks on Jbrowse. Four cultures were of cells with ura4 silenced by cen1 heterochromatin. The other four cultures were\nof a strain without ura4. By passaging the cultures in 5-FOA we selected against cells with defects in heterochromatin. Genes that contributed to the formation of heterochromatin exhibited fewer insertions in cells with the cen1 copy of ura4 relative to the strain lacking ura4. To distinguish genes critical for heterochromatin from genes that contribute to a lesser extent we passaged cultures in 5-FOA for 5 generations and for 80 generations. While viewing these integration sites can indicate whether genes of interest contribute to heterochromatin formation you can also examine insertions in the cultures lacking ura4 to gage whether specific genes or noncoding sequences make significant contributions to growth.”\n\nNew genome browser datasets 2020-09-08\n\n2020-09-08\n\nThree new datasets in are now available in PomBase JBrowse (links go to PomBase publication pages, which in turn link to the browser with the tracks enabled):\n\n-  Transcription start sites from\n Li H, Hou J, Bai L, Hu C, Tong P, Kang Y, Zhao X, Shao Z. 2015.\n Genome-wide analysis of core promoter structures in Schizosaccharomyces pombe with DeepCAGE.\n PMID:25747261 DOI:10.1080/15476286.2015.1022704\n\n-  Transcript data from\n Eser P, Wachutka L, Maier KC, Demel C, Boroni M, Iyer S, Cramer P, Gagneur J. 2016\n Determinants of RNA metabolism in the Schizosaccharomyces pombe genome.\n PMID:26883383 DOI:10.15252/msb.20156526\n\n-  Transposon insertion sites from\n Lee SY, Hung S, Esnault C, Pathak R, Johnson KR, Bankole O, Yamashita A, Zhang H Levin HL.\n Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation.\n PMID:32101745 DOI:10.1016/j.celrep.2020.01.094\n\nSubmit your genome browser data\n\n2020-09-08\n\nWe have updated our HTP data submission procedure to make it easier for you to contribute your datasets for PomBase JBrowse:\n\nWe now provide spreadsheet templates in Excel and Open Document formats that gather the metadata we need to load and display your data. You can download a template from the documentation page on HTP data submission. Send completed spreadsheets to the PomBase helpdesk.\n\nPublished: GO Term Matrix for annotation QC\n\n2020-09-02\n\nIn collaboration with the GO Consortium, the PomBase team has published a report on the Term Matrix approach to GO annotation quality control. The article, out this week in Open Biology, describes biological processes that do, or don’t, share annotated gene products, and how we use co-annotation patterns to build rules to detect, correct, and prevent errors.\n\nPombeTalks September 2nd\n\n2020-09-01\n\nThe next online PombeTalks will take place on Wednesday 2nd September 2020 at 17:00 Central European Time:\n\n-  François Bachand, USherbrooke, Canada: Proximity-dependent biotinylation assays in fission yeast and a tale about slow RNA polymerase II transcription\n\n-  Scott Curran, Nurse Lab, The Crick Institute, UK: A quantitative and spatial analysis of the cell cycle control network\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on September 16, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\n11th Pombe meeting postponed to 2022\n\n2020-08-19\n\nDue to the ongoing Covid-19 pandemic, the 11th International Fission Yeast Meeting, due to take place in Hiroshima, Japan, has been postponed.\n\nThe new dates will be 12th (Sun -17th (Fri) June, 2022.\n\nPlease see the conference website and pombelist for further announcements.\n\nPombeTalks August 19th\n\n2020-08-12\n\nThe next online PombeTalks will take place on Wednesday 19th August 2020 at 17:00 Central European Time:\n\n-  Joe Magliozzi, Moseley Lab, Dartmouth: Cell polarity kinases regulate RNA-binding protein Sts5 to control cell shape\n\n-  Ramakanth Neeli, Minc Lab, Institute Jacques Monod: Mechanisms and Functions of Cell Wall Mechanosensing in Fission Yeast\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on September 2, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks August 5th\n\n2020-07-31\n\nThe next online PombeTalks will take place on Wednesday 5th August 2020 at 17:00 Central European Time:\n\n-  Feng Li, Levin Lab NICHD/NIH, USA: Identification of an integrase-independent pathway of retrotransposition\n\n-  Ivan Surovtsev, King lab, Yale University, USA: Liquid-liquid phase separation, heterochromatin domains and nuclear mechanics\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on August 19, and the summer schedule is available. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nFission yeast microPublications\n\n2020-07-22\n\nPomBase has recently joined microPublication.org, which “publishes brief, novel findings, negative and/or reproduced results, and results which may lack a broader scientific narrative”, as a Partner Database. Fission yeast researchers can thus now make any results available to the community, even those that don’t fit neatly into traditional publications.\n\nVisit the microPublications website to learn more, to register and submit your data, or sign up to review. Send questions to the PomBase helpdesk.\n\nPombeTalks July 22nd\n\n2020-07-21\n\nThe next online PombeTalks will take place on Wednesday 22nd July 2020 at 17:00 Central European Time:\n\n-  Prof. Dr. Ann Ehrenhofer-Murray, Institut für Biologie, Humboldt-Universität zu Berlin: Queuosine and m5c modification of RNA: Nutritional control of translation in S. pombe homestasis\n\n-  Dr. Sarah Sabatinos, Department of Chemistry and Biology, Ryerson University: Long-term effects of surviving replication instability\n\n-  PomBase microPublications announcement (Midori Harris)\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on August 5, and the summer schedule is available. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks July 8th\n\n2020-07-02\n\nThe next online PombeTalks will take place on Wednesday 8th July 2020 at 17:00 Central European Time:\n\n-  Sahana Holla, Grewal lab, NIH: Positioning heterochromatin at the nuclear periphery promotes epigenetic inheritance\n\n-  Nick Rhind, UMass Medical School: Cell size is controlled by size-dependent expression of mitotic activators\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on July 22nd, and the summer schedule is available. If you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nPombeTalks June 24th\n\n2020-06-19\n\nThe next online PombeTalks will take place on Wednesday 24th June 2020 at 17:00 Central European Time:\n\n-  Sito Torres-Garcia, Allshire lab, University of Edinburgh: Epigenetic gene silencing by heterochromatin primes fungal resistance\n\n-  Julie Rich-Robinson, Das lab, University of Tennessee: Cell-cycle-dependent cues temporally regulate Cdc42 activity at growth sites in fission yeast\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up.\n\nA schedule is now available for the rest of the summer, including the next talks on July 8th. If you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nEditable PomBase query names\n\n2020-06-11\n\nEntries in the PomBase advanced search query history now show brief, user-editable query descriptions, and a toggle to show or hide additional details.\n\nPombeTalks POSTPONED to June 17th\n\n2020-06-05\n\nPlease note that the next online PombeTalks will take place one week later than originally planned, to support the STEM Strike for Black Lives on 10th June.\n\nIn the meantime, please complete this brief survey of the audience.\n\nOn Wednesday 17th June 2020 at 17:00 Central European Time, the speakers will be:\n\n-  Gautam Dey, Baum lab, UCL / EMBL Heidelberg: Closed mitosis requires local disassembly of the nuclear envelope\n\n-  Meredith Betterton, UC Boulder: Computational modeling of fission yeast mitosis: what we can learn about pombe from computer simulations\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. The next two sessions will b on June 27 and July 8. If you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nPombeTalks May 27th\n\n2020-05-21\n\nThe next online PombeTalks will take place on Wednesday 27 May 2020 at 17:00 Central European Time. This time, in addition to the usual pair of research talks, our own Val Wood will show a few of PomBase’s lesser-known features.\n\n-  Angad Garg, Stewart Schuman’s lab, Memorial Sloan Kettering Cancer Center: Long non-coding RNA control of phosphate homeostasis\n\n-  José López Hernández, Sarah Zander’s lab, Stowers Institute for Medical Research: Diverse mating strategies in S. pombe affect the spread of wtf meiotic drivers\n\n-  Val Wood, PomBase: Hidden corners of PomBase: Ten features you might not have seen\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also mark your calendars for the next two sessions on and June 10 and 24, and if you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nNew fission yeast GO slims\n\n2020-05-20\n\nTo complement the overview provided by the fission yeast GO biological process slim, we have created GO slims for the molecular function and cellular component branches of GO. Each slim page provides links to ontology term pages, annotated genes, and to download files containing the slim terms and IDs.\n\nNew ontology slimming options for advanced search results\n\n2020-05-20\n\nThe PomBase advanced search results panel now allows you to retrieve annotations to any of the fission yeast GO slims or the Mondo disease slim for genes in the results list. For example, you can query for all genes involved in a process and slim the resulting list by molecular function or disease association.\n\nPomBase adopts MONDO for disease gene curation\n\n2020-05-18\n\nPomBase has switched from the Disease Ontology (DO) to the Monarch Initiative’s Mondo Disease Ontology (Mondo) for disease gene curation. Mondo covers the same set of disease descriptions as DO, but has a richer hierarchical structure that classifies more specific descriptions into broad categories (e.g. anemia, cancer, kidney disease) suitable for a disease “slim” term set.\n\nPomBase curators are collaborating with Mondo to improve its disease classification, especially in areas that will support inferences that improve fission yeast disease annotation coverage in the new PomBase Mondo slim. The new disease slim is a work in progress, so if there is a particular disease grouping that you would find useful, please let us know.\n\nImproved gene-disease curation\n\n2020-05-18\n\nPomBase disease gene curation associates disease descriptors with fission yeast orthologs of human disease-causing genes. We have now increased coverage by adding new gene–disease term connections, with 3954 individual annotations to 1195 genes (up from 2588 and 905 respectively in January 2019). Disease associations now cover 24.5% of all fission yeast protein-coding genes, and over one third of those with human orthologs.\n\nPublished: Community curation in PomBase\n\n2020-05-11\n\nThe PomBase team has published an overview of our experience with community curation for fission yeast. In the article, out this week in Database, we reflect on the factors that have made our community’s remarkable, standard-setting achievements possible, and on the benefits we and PomBase users derive from this effort. We highlight the collaboration between authors and professional curators that arises via community curation, and how annotation quality improves as a result.\n\nWatch for invitations to curate your new papers, or see our community curation page for more information.\n\nPombeTalks May 13th\n\n2020-05-07\n\nThe next online PombeTalks will take place on Wednesday 13 May 2020 at 17:00 Central European Time. Speakers:\n\n-  Sarah Lambert, Institut Curie, Paris, France: Resolution of replication stress in space and time for maintaining genome stability\n\n-  Cornelia Kilchert, Justus-Liebig-University, Giessen, Germany: RNA-binding proteins in fission yeast - a global perspective\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also mark your calendars for the next two sessions on May 27 and June 10, and if you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nChromatin silencing ontology & annotation overhaul\n\n2020-05-07\n\nPomBase curators have collaborated with the GO Consortium to improve the representation of chromatin silencing and the underlying heterochromatin organization processes in the GO biological process ontology and annotations.\n\nNotably, “chromatin silencing” terms have been removed from GO on the grounds that they conflated various heterochromatin assembly, formation, and maintenance pathways with processes that affect chromatin-mediated repression more indirectly (e.g. tethering to the nuclear envelope). Chromatin silencing is a phenotype resulting from the cumulative effects of these processes, and the Fission Yeast Phenotype Ontology (FYPO) accordingly retains a full suite of “chromatin silencing” terms.\n\nAnnotations using the GO chromatin silencing terms were reviewed, and either removed or reannotated based on what could be inferred from the phenotypes, resulting in a substantially revised set of heterochromatin assembly annotations. Further work is required, so please send us any corrections.\n\nPomBase now uses InterPro Version 79.0\n\n2020-05-05\n\nPomBase now uses InterPro Version 79.0, which integrates:\n\n-  128 new InterPro entries\n-  An update to PIRSF [3.10]\n-  151 new methods from the SUPERFAMILY (4), CATH-Gene3D (6), PIRSF (9), PANTHER (106), and CDD (26) databases.\n\nInterPro cites 48466 publications in PubMed. See the InterPro release notes for further information.\n\nMitochondrial genome update\n\n2020-05-01\n\nThe mitochondrial genome sequence in PomBase has been updated to reflect corrections made in Tao et al. (2019) “Intraspecific Diversity of Fission Yeast Mitochondrial Genomes”.\n\nMidori Harris receives 2020 Biocuration Career Award\n\n2020-04-28\n\nMidori Harris, ontology developer and curator at PomBase, has been awarded the 2020 Biocuration Career Award.\n\nCongratulations to Midori and a huge thanks for all that you do for PomBase.\n\nPombeTalks start on April 29th\n\n2020-04-22\n\nThe first in the new series of online PombeTalks will take place on Wednesday 29 April 2020 at 17:00 Central European Time. Speakers:\n\n-  Aleksandar Vjeṧtica, Sophie Martin’s lab, University of Lausanne: Cycling for reproductive fidelity: Coupling the cell cycle and re-fertilisation blocks ensures ploidy maintenance during sexual lifecycle\n\n-  Haitong Hou, Julia Cooper’s lab, NCI & University of Colorado: Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also mark your calendars for the next two sessions on May 13 and May 27, and if you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nAnGeLi update\n\n2020-03-23\n\nAnGeLi (developed by Danny Bitton) is a tool that allows you to perform enrichments over gene lists.\n\nAnGeLi has recently been updated to provide 9320 lists, including ontology-based annotations from PomBase (as of 2020-03-04) as well as many additional datasets from the Bähler laboratory.\n\nNew search result download options\n\n2020-03-23\n\nThe PomBase Advanced search has added new options to the data you can download for your query results:\n\n-  All physical interactors of a gene product\n-  Deletion viability\n-  Protein length\n\nPomBase now uses InterPro Version 77.0\n\n2020-03-01\n\nPomBase now uses InterPro Version 77.0, which integrates 145 new methods from the CATH-Gene3D (134), and SUPERFAMILY (11) databases. InterPro cites 59894 publications in PubMed. See the InterPro release notes for further information.\n\nCommunity curation response rate reaches 50%\n\n2020-02-28\n\n789/1587 publications assigned to community members for curation are finished. A big thank you to everyone who has participated so far. For more details, and all our curation metrics, see https://curation.pombase.org/pombe/stats/annotation\n\nA quarter of a million annotations\n\n2020-02-20\n\nPomBase recently reached 250,000 annotations to controlled vocabularies and ontologies. The majority (over 90%) are assigned manually from fission yeast experimental data derived from 3776 publications, most of which report low-throughput, hypothesis-driven experiments.\n\nYou can query and combine any of these data types in the Advanced search.\n\nThank you to everyone who contributed to this significant achievement through community curation.\n\nQuery phenotypes for conditions\n\n2020-02-05\n\nThe PomBase advanced search Advanced search now supports using experimental conditions as search criteria for phenotype annotations. For example, you can now query for genes that show abnormal chromosome segregation mutant phenotypes specifically at high or low temperatures. The search uses the same condition descriptors as Canto and the PomBase web pages.\n\nNote that phenotype queries that have condition constraints can be combined, but pay careful attention to the annotations for the results. Future work will add support for querying for multiple conditions on the same annotation, and for specifying conditions to exclude from results.\n\nLevures, Modèles et Outils 14th International Conference\n\n2020-02-04\n\nThe 14th edition of the “Levures, Modèles et Outils” meeting (LMO14) will be held in July 9-11, 2020, at the University of Strasbourg in France. Registration is open February 3rd to June 30th, and abstracts can be submitted from February 3rd to April 10th. Authors will be notified in early May and the final program will be available in early June.\n\nThe sessions will be diverse and present the latest findings using yeast as a model organism on the following topics:\n\n1.  Cell biology, cell cycle, cytoskeleton\n2.  Gene expression regulation\n3.  Population, functional and evolutionary genomics\n4.  Replication, repair and recombination\n5.  Transport, sensing and signaling\n6.  Pathogenic yeast and filamentous fungi\n7.  Tools, resources and databases\n8.  New technologies, yeast and industry\n\nPomBase is now an ELIXIR Node Service\n\n2020-01-17\n\nPomBase has been awarded Node Service status by the UK node of ELIXIR. ELIXIR-UK Node Services support the bioinformatics and broader biological research communities by providing training and resources that help researchers to find and share data, exchange expertise, and agree on best practices at national, European and international levels. The review panel describes PomBase as a “mature, leading model organism database which is popular, unique, well used, and has a strong user community.”\n\nNew vectors for simple, reliable S. pombe molecular biology\n\n2020-01-07\n\nTo enable fission yeast researchers to manipulate S. pombe molecular biology reproducibly and easily, Aleks Vještica and Magdalena Marek in Sophie Martin’s lab have designed and constructed a series of simple, fully characterized plasmids.\n\nThe Stable Integration Vector (SIV) series provides a highly modular toolbox to introduce heterologous sequences more stably was possible with than previously available vectors. The toolkit includes antibiotic resistance markers, promoters, fluorescent tags, and terminators, as well as large set of ready-to-use fluorescent probes to mark organelles and visualize cellular processes.\n\nThe work is published in the Journal of Cell Science, and a PomBase publication page is available.\n\nUnique permanent URLs for search results\n\n2019-11-28\n\nAll result pages from the Advanced search now have a unique permanent URL that can be bookmarked and shared with your colleagues.\n\nThe QuiLT and GO slim pages also now have permanent URLs.\n\nBrowser tracks now loadable from publication pages\n\n2019-10-16\n\nData tracks from datasets hosted in the PomBase genome browser can now be browsed and loaded from their respective publication pages. For an example, see Atkinson et al. (2018). Data tracks are now also downloadable from the publication pages.\n\nNew PomBase funding from the Wellcome Trust\n\n2019-10-07\n\nWe are pleased to announce that the recent PomBase application for continued Wellcome Trust funding was successful. Although the grant was not fully funded, we are confident that we can cover the shortfall by small grants for stand-alone projects and collaborations. We would like to thank the pombe community for their support with the application, and the Wellcome Trust for their continued funding. We look forward to supporting your research until 2025 (and beyond).\n\nPomBase now uses InterPro Version 76.0\n\n2019-10-06\n\nPomBase now uses InterPro Version 76.0, which integrates 277 new methods from the CATH-Gene3D (1), PANTHER (178) and CDD (98) databases. InterPro cites 59846 publications in PubMed. See the InterPro release notes for further information.\n\nReplication origin data loaded into JBrowse\n\n2019-08-30\n\nWe have loaded data from: Segurado et al. (2003) “A+T-rich islands”, Hayashi et al. (2007) “Pre-replicative complex localization; early and late firing origins”, and Mickle et al. (2007) “Replication origins with functional classification”.\n\nTo view the tracks, either follow the hyperlinks above to the respective PomBase publication pages, and click on the “view” link after “Datasets from this publication are available in the PomBase JBrowse genome browser”, or go directly to the browser and click on the “select tracks” button to find the tracks manually.\n\nFor anyone new to JBrowse we have a quick start guide.\n\nJoin the conversations on Slack\n\n2019-07-19\n\nThe vibrant fission yeast community now has a Slack channel. Slack provides a forum for the research community. Follow conversations you care about, message colleagues privately, or in groups, ask questions, post responses. All archived and searchable.\n\n-  See the PombeSlack flyer for more information, including how to join.\n\n“Fitness Landscape of the Fission Yeast Genome” dataset loaded into JBrowse\n\n2019-07-11\n\nWe have loaded the Grech et al. (2019) “Fitness Landscape of the Fission Yeast Genome” dataset into JBrowse. In this study, transposon mutagenesis libraries were created to map transposon insertion sites in the S. pombe genome. From this data, functional elements of the genome were inferred. The tracks from this study can be loaded by a single click from the linked publication page above\n\nThanks Dan Jeffares for sending us the data.\n\nFor anyone new to JBrowse we have a quick start guide.\n\ntRNA metabolism GO annotation update\n\n2019-05-19\n\nThe process of tRNA metabolism, and the associated molecular functions have recently been reviewed.\n\n-  “tRNA metabolic process” annotation\n-  genes for “tRNA metabolic process”\n\nPlease let us know if the annotation can be further improved.\n\nCustomisable FASTA download\n\n2019-04-18\n\nYou can now download nucleotide or peptide sequences for genes in Advanced search results in FASTA format, and customise what is included in the FASTA headers (e.g. gene names, product descriptions, sequence coordinates, or various IDs can be included).\n\nNew homology modelling and ortholog links on gene pages\n\n2019-04-18\n\nWe have added new external links to PomBase gene pages for structure and ortholog predictions:\n\n-  Protein-specific links to SWISS-MODEL, a fully automated protein structure homology-modelling server, accessible via the ExPASy web server, lead to a SWISS-MODEL Repository page for each sequence and present results. If no structure or model is available, you can either trigger adding an entry to the repository with a single click or easily interactively search for templates and build models in your own SWISS-MODEL workspace.\n\n-  Ensembl Fungi Compara and Ensembl Pan-taxonomic Compara links lead to orthology predictions from the Ensembl Compara pipeline for fungi and all species, respectively.\n\n-  PANTHER links retrieve gene information, classification, and predicted orthologs.\n\nPomBase InterPro Update\n\n2019-04-17\n\nPomBase now uses InterPro Version 73.0, which integrates 1,531 new methods from the CATH-Gene3D (122), CDD (330), PANTHER (1075), Pfam (2), PROSITE profiles (1) and TIGRFAMs (1) databases, and covers 81.2% of UniProt Knowledgebase release 2019_02.\n\nSee the news item at InterPro for additional information, including release notes.\n\nS. pombe included in Gene Info browser extension\n\n2019-04-16\n\nS. pombe gene information is now included in the Gene Info extension (GIX) for the Chrome and Firefox web browsers. GIX allows you to retrieve information about a gene product directly on any webpage simply by double clicking an official gene name, synonym or supported accession. Searching or double-clicking on text terms retrieves gene function annotation, GO terms, external database links, and interaction data drawn from BioGRID and IntAct. Retrieved gene names are automatically hyperlinked for rapid recursive searches.\n\nGeneInfo is fully open source, available online at GitHub. Tutorial videos, a step-by-step guide, and download links for Firefox Add-ons and the Chrome web storeare available online. GeneInfo was developed by James Knight in the Gingras Lab at the Lunenfeld-Tanenbaum Research Institute in Toronto, Canada.\n\nIntegrated motif search\n\n2019-03-19\n\nThe PomBase motif search has been fully integrated into the website, and allows users to find protein motifs and send them directly to the PomBase advanced search.\n\nICYGMB 2019 - registration open\n\n2019-03-13\n\nRegistration is now open for the 29th International Conference on Yeast Genetics and Molecular Biology (ICYGMB), which returns to Gothenburg, Sweden, August 18-22, 2019.\n\nYeast2019 is the meeting of the international yeast research community where the latest, and even unpublished results are exchanged, and new projects, alliances, and collaborations are founded. Featuring 55 confirmed speakers including keynote lectures by Susan Gasser, Roger Kornberg and Frederick Roth, this conference will contain important news and information for all yeast researchers. A do-not-miss-event.\n\nGO slim for any S. pombe gene list\n\n2019-03-05\n\nPomBase’s advanced search now allows you to retrieve GO slim annotations for any set of search results. To find GO slim annotations for your own list of S. pombe genes, use the advanced search “Gene names and IDs” option, and then use the “Slim” button on the search results page.\n\nSee the fission yeast GO slim page and the advanced search documentation for more information.\n\nSouth Eastern Regional Yeast Meeting (SERYM) - registration open\n\n2019-03-04\n\nRegistration is now open for the 26th annual South Eastern Regional Yeast Meeting (SERYM), which will be held April 12-14, 2019, in Atlanta, GA, USA.\n\nFission yeast’s own Susan Forsburg is the keynote speaker. The meeting brings together researchers who use any type of yeast as a model system, covering diverse, interdisciplinary topics from strategies for treatment of fungal disease to modeling human disease in yeast.\n\nIcon: SERYM 2019\n\nInternational Cell Cycle meeting - registration open\n\n2019-02-27\n\nRegistration is now open for the Inaugural Trieste Cell Cycle Meeting, which will be held June 3-6, 2019, in Trieste, Italy.\n\nThis is the first of a planned series of biennial cell cycle meetings that will take place in Europe, and will alternate with the Salk Cell Cycle meetings held on the US west coast.\n\nOrganisers Rob de Bruin, Snezhana Oliferenko, Rosella Visintin and Peter Thorpe hope to see you there!\n\nIcon derived from meeting image; credit: Chantal Roubinet, Baum lab\n\nPublished: Hidden in plain sight: What remains to be discovered in the eukaryotic proteome?\n\n2019-02-20\n\nOur analysis of conserved unknown proteins has now been published in Open Biology. In it, PomBase curators consider the challenges and opportunities that conserved, but persistently unstudied, proteins pose for diverse areas of basic and applied biology. We develop metrics to define unknown lists, provide unknown inventories for human and yeast, and classify S. pombe unknowns by numerous orthogonal attributes, all with a view to drawing attention to the unknowns to alleviate their neglect.\n\nPombe 2019 - registration open\n\n2019-02-15\n\nRegistration for the 10th International Fission Yeast Meeting is now open!\n\nThe conference will take place July 14-19, 2019, in Barcelona, Spain. Early registration closes on April 15th — or when capacity is reached. Please see the conference website for more information, including registration final deadline and costs (some travel grants are available), abstract submission, programme, accommodation, and logistics.\n\nVal Wood wins Biocuration society award\n\n2019-02-12\n\nCongratulations to PomBase project leader Val Wood, who has received the 2019 Exceptional Contributions to Biocuration Award from the International Society for Biocuration. Read more at the ISB site\n\nImproved disease association dataset released\n\n2019-01-09\n\nWe are pleased to announce the release of our improved human disease mappings dataset. This dataset connects human disease causing genes to their S. pombe orthologs.\n\nDiseases are now mapped to the Disease Ontology (DO) and the dataset has been extended by data from Malacards. All disease associations can be accessed from the top level disease page. A disease slim has been created to facilitate browsing of disease categories. Currently, 907 S. pombe genes are associated with disease (up from 610 in the original dataset). This number is due to increase as mappings are still in progress.\n\nMany thanks to DO and Malacards for help in improving this annotation set. Icon courtesy of Julie McMurry.\n\nMitochondrial GO annotation update\n\n2018-12-17\n\nResponding to increasing interest in mitochondrial biology, especially relating to ageing, neurogenerative diseases, and processes at the ER-mitochondrion interface, we have reviewed S. pombe mitochondrial GO annotations. Although there is still relatively little fission yeast-derived experimental data in this area, we have refined many inferred annotations for mitochondrial complexes and sub-components as well as some for processes.\n\nYou can see all 753 S. pombe mitochondrial annotations on the ontology term page for mitochondrion (GO:0005739).\n\nIcon courtesy of Reactome.\n\nNew nucleosome occupancy maps loaded\n\n2018-12-03\n\nWe have loaded the nucleosome occupancy maps as described in González et al. (2016) PMID: 27662899. This dataset was generated using the paired-end sequencing protocol of Illumina and thus those maps are of higher resolution than those made with single-end (SE) sequencing hosted in the browser since before.\n\nHere is a link that loads the tracks in PomBase JBrowse. And here is a link to our JBrowse quickstart guide.\n\nMany thanks to Paco Antequera for sending us the bigwig files! If you would like us to load any datasets then please get in touch.\n\nSee your genes in a QuiLT\n\n2018-11-21\n\nPomBase now offers a new way to display gene lists graphically based on multiple orthogonal annotation types — the Quick Little Tool (QuiLT) for visualisation.\n\nInspired by our recent analysis of conserved unstudied proteins (see figures 4 and S1 in the manuscript at bioRxiv), QuiLT allows you to create a similar figure for any gene list you create or import using the advanced search. To use QuiLT, follow the link to your search results, then click the “Visualise” button. QuiLT visualisation is also available from the PomBase pages that list genes annotated to an ontology term, and on the Priority unstudied genes page.\n\nTo see the Unknowns dataset in QuiLT, visit the unknowns results page and click “Visualise”.\n\nThe QuiLT display is interactive, and you can:\n\n-  Highlight subsets of the list, and filter the display\n-  Toggle annotation types on and off\n-  Reorder the list to focus on features of most interest\n-  Download the image\n\nSee the QuiLT documentation for more information, and contact the curators if you have comments, questions or suggestions.\n\nMany thanks to our star (and only) programmer, Kim Rutherford, for developing QuiLT.\n\nFission yeast transmembrane transport overhaul\n\n2018-11-20\n\nThe Gene Ontology “transmembrane transport” branch has recently been substantially revised. In line with these revisions, PomBase has standardised gene product descriptions for transporters, and overhauled GO annotations to be as complete and comprehensive as possible based on current knowledge.\n\nIcon courtesy of Reactome.\n\nHidden in plain sight: What remains to be discovered in the eukaryotic proteome?\n\n2018-11-17\n\nIn a new publication, PomBase curators consider the challenges and opportunities that conserved, but persistently unstudied, proteins pose for diverse areas of basic and applied biology. To draw attention to these proteins, we develop metrics to define unknown lists, provide unknown inventories for human and yeast, classify S. pombe unknowns by numerous orthogonal attributes, and speculate about reasons for their neglect.\n\nA pre-publication manuscript is available at bioRxiv.\n\nPomBase in your pocket\n\n2018-11-14\n\nOur usage statistics informed us that over 20% of devices accessing PomBase are smartphones or tablets. We therefore spent some time optimizing the display for small screens. We hope that you will continue to enjoy PomBase on the go!\n\nCelebrating 20 years of GO\n\n2018-11-08\n\nPomBase curators are major contributors to the Gene Ontology (GO) project — ontology content, annotations, and QC procedures — and co-authors on the new GO NAR Database Issue paper.\n\nWe recommend citing the GO and PomBase NAR papers when you use GO data in your analyses.\n\nRNA central and PomBase\n\n2018-11-06\n\nRNAcentral is a comprehensive database of non-coding RNA sequences. PomBase is an RNAcentral Consortium member, and all of the curated non-coding RNAs from PomBase will be available in RNAcentral soon. For more information, see their recent NAR Database Issue paper, as well as current search results for S. pombe RNAs.\n\nNew PomBase genomic region graphics\n\n2018-10-23\n\nPomBase gene pages now use interactive graphics from PomBase JBrowse to depict the genomic region around the gene. Drag to scroll left and right, double-click to zoom in, shift-double-click to zoom out, and click a feature to see details in a popup. The “Full-screen view” link in the corner opens the fully functional JBrowse in a new tab or window. Reloading a gene page restores the display to the default location and zoom level.\n\nPomBase NAR Database Issue\n\n2018-10-15\n\nOur NAR database update “PomBase 2018: user-driven reimplementation of the fission yeast database provides rapid and intuitive access to diverse, interconnected information” is now available. We have updated the Citing PomBase to recommend citing this new paper. Thank you all for guiding the development of the new, improved PomBase, and for your continued usage, curation contributions, and suggestions!\n\nFungal Pathogen Genomics Course 2019 - registration open\n\n2018-10-10\n\nRegistration for the 2019 Fungal Pathogen Genomics Course is now open. The course is hosted by Wellcome Genome Advanced Courses and Scientific Conferences, and will take place May 7-12, 2019, at the Wellcome Genome Campus, Hinxton, UK. Course content provides hands-on training on how to: - Take advantage of unique tools offered by FungiDB, EnsemblFungi, PomBase, SGD/CGD, and MycoCosm/JGI; - Develop testable hypotheses; - Investigate transcriptomics, proteomics and genomics datasets across multiple databases and different user interfaces. Please see the course website for more information, including how to apply, costs (limited bursaries are available), programme, and logistics.\n\nTranscript tracks from Atkinson et al. (2018) loaded\n\n2018-10-06\n\nWe are very pleased to announce that we have loaded the transcript tracks from Atkinson et al. (2018) into the PomBase JBrowse genome browser. For a brief introduction to getting started with PomBase JBrowse, please see our documentation page. If you have published data that you would like to see hosted, please get in touch.\n\npombelist changes\n\n2018-08-31\n\nThe pombe community mailing list, “pombelist”, is now hosted by the University of Cambridge. The new address for posting messages is pombelist@pombase.org. The link to subscribe has also changed.\n\nNew genome browser tracks\n\n2018-05-28\n\nWe are very pleased to announce that we have loaded a number of new datasets into the PomBase [JBrowse genome browser (https://www.pombase.org/jbrowse/). These include:\n\n-  Thodberg et al. (2018) - CAGE-defined transcription start sites across 5 different conditions\n-  Yadav et al. (2012) - G(x) scores specifying the amount of free energy needed to melt base pairs in the DNA duplex at different genomic locations\n-  A PomBase-generated dataset of promoter elements across the genome (computational matching of the consensus promoter sequences to the reference DNA sequence)\n-  Intron branch points from Bitton et al. (2014) which was also available in the Ensembl browser.\n\nFor anyone wanting a quick introduction to our genome browser, Antonia Lock has written “Getting started with PomBase JBrowse”, a basic guide that covers loading tracks, navigating the browser, what metadata we provide, and more.\n\nNew book chapter about PomBase\n\n2018-05-22\n\nPomBase has a new book chapter in Eukaryotic Genomic Databases (Methods and Protocols). This chapter provides insight into the curation philosophy and data organization at PomBase, and provides a guide to using PomBase tailored for infrequent visitors and anyone considering extending their research to include S. pombe. The chapter is free to download courtesy of the Wellcome Trust.\n\nPomBase releases JBrowse\n\n2018-04-16\n\nPomBase has now implemented JBrowse, from the GMOD project, as its genome browser. The new browser offers a number of improvements over the old:\n\n-  Quick, responsive scrolling and zooming\n-  Simple track selection interface\n-  Intuitive controls\n-  Simplified data submission pipeline behind the scenes\n-  More informative track metadata\n\nIn memory of André Goffeau\n\n2018-04-05\n\nSadly, PomBase staff and the fission yeast community note the death of André Goffeau on April 2, 2018. In addition to initiating and coordinating the sequencing of the budding yeast genome, Prof. Goffeau will be remembered for his contributions to the fission yeast genome project and for his knowledge, leadership, and friendship.\n\nCongratulations to GSA award winners\n\n2017-11-24\n\nThe Genetics Society of America (GSA) has announced two award winners familiar to the model organism database world:\n\n-  Ira Herskowitz Award: Mike Cherry, Stanford University\n-  Lifetime Achievement Award: Steve Oliver, University of Cambridge\n\nThe awards will be presented at the next Yeast Genetics Meeting, at Stanford University in August 2018. Congratulations and thanks to Mike and Steve!\n\nNew, improved PomBase goes live\n\n2017-10-24\n\nThe new PomBase web site, which has been under development during 2017, has been released. The new site features:\n\n-  Nightly data updates\n-  New publication pages\n-  New genotype pages\n-  Improved ontology term pages\n-  Improved summary views for annotation displays\n-  Phenotype annotation display filtering\n-  Faster querying in the advanced search\n-  Front page research and community curation highlights\n-  Streamlined back-end data storage and retrieval\n\nWe thank the members of the fission yeast research community who have followed its progress via the preview site, and welcome feedback from all users.\n\n9th International Fission Yeast Meeting - early registration closes soon\n\n2016-12-11\n\nReminder: early registration for the 9th International Fission Yeast Meeting in Banff closes Dec. 31, 2016. Please see the conference website at www.pombe2017.com for details.\n\n9th International Fission Yeast Meeting registration open\n\n2016-10-31\n\nRegistration for the 9th International Fission Yeast Meeting is now open. The meeting will be held in Banff, Canada from May 14-19, 2017. Early registration closes Dec 1, 2016! Please see our website at www.pombe2017.com for details. We look forward to seeing you in Banff!\n- Conference Organizers: Dallan Young, Gordon Chua, Paul Young\n\nPomBase data update 2016-10-19\n\n2016-10-19\n\nWe have updated the data available on the PomBase web site to include manual curation through September 11, 2016.\n\nShow your support for database funding\n\n2016-06-27\n\nIn response to planned cuts to database funding, leading model organism researchers have prepared an open letter to NIH Director Dr. Francis Collins to demonstrate support for the independent community-focused databases that are essential to their work. Although PomBase is not directly funded by NIH, we collaborate extensively with those that are, including the GO Consortium and several model organism databases.\nThe Genetics Society of America website where the letter can be viewed and signed is at http://www.genetics-gsa.org/MODsupport\nPlease sign the letter to add your voice in support of the databases that help make your research possible. For more information, we recommend an email that Mike Cherry sent to the GO-Friends mailing list, archived at https://mailman.stanford.edu/pipermail/go-friends/2016-June/002355.html\n\nOur model organism database commentary\n\n2016-06-15\n\nSeveral of the PomBase staff, joined by our advisor Sir Paul Nurse, have published a Comment in BMC Biology briefly describing the importance of model organism databases to the success of modern biomedical research:\nOliver SG, Lock A, Harris MA, Nurse P, Wood V. 2016. Model organism databases: essential resources that need the support of both funders and users.\nBMC Biol. 2016 14(1): 49. doi: 10.1186/s12915-016-0276-z. PMID:27334346\n\nPomBase data update 2016-05-31\n\n2016-05-31\n\nWe have updated the data available on the PomBase web site to include manual curation through May 12, 2016.\n\nPomBase data update 2016-05-09\n\n2016-05-09\n\nWe have updated the data available on the PomBase web site to include manual curation through April 8, 2016.\n\nPomBase data update 2016-04-11\n\n2016-04-11\n\nWe have updated the data available on the PomBase web site to include manual curation through March 9, 2016.\n\nImportant: We have corrected a problem that made erroneous interaction data and literature appear on some gene pages.\n\nThe gene pages now include interaction data from the Vo et al. proteome-wide study (curated by BioGRID and imported into PomBase):\nVo TV et al. 2016. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Cell 164(1-2): 310-23. doi: 10.1016/j.cell.2015.11.037 PMID:26771498.\n\nThe genome browser now includes transcriptome data published in:\nEser P, Wachutka L, Maier KC, Demel C, Boroni M, Iyer S, Cramer P, Gagneur J. 2016. Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Mol Syst Biol. 12(2): 857. doi: 10.15252/msb.20156526 PMID:26883383.\n\nPomBase data update 2016-02-11\n\n2016-02-11\n\nWe have updated the data available on the PomBase web site to include manual curation through January 25, 2016.\nThe genome browser includes variation data, in tracks under “Variation”, from natural S. pombe isolates, published in:\nJeffares DC et al. 2015. The genomic and phenotypic diversity of Schizosaccharomyces pombe. Nat Genet. 47(3): 235-241. doi:10.1038/ng.3215 PMID:25665008\n\nNew files are now available from the PomBase FTP site, and are linked from pages in the Download Datasets area:\n\n-  Non-coding RNA sequence feature coordinates (available via the Data Mappings page);\n-  Protein features, such as domains and family assignments (available via the Protein Datasets page);\n-  Protein modification annotations (also in Protein Datasets).\n\nThe New and Removed Genes page has been updated to reflect recent deletions and merges.\nNote: Ontology graph views are no longer available in the genome browser, so links have been removed from the GO, FYPO, and modification tables on the gene pages. For GO and FYPO, links to external ontology browsers that offer graphical views are available on the Ontology Term pages.\n\nPomBase data update 2015-12-02\n\n2015-12-02\n\nWe have updated the data available on the PomBase web site to include manual curation through November 9, 2015, including 340 community-curated publications.\n\nNew Advanced Search features\n\n2015-12-02\n\nWe have introduced new features to the Advanced Search:\n\n-  There are now two query reuse options: store a query in your web browser cache, or download a JSON file that can be uploaded later to re-run.\n-  You can now query for genes that interact genetically or physically with a specified gene.\n-  The FYPO query now offers options to choose nulls (deletions or disruptions), wild-type overexpression, or all alleles. The search results will include any genes that have an allele that matches the allele criteria and the chosen phenotype.\n\nNew genetics primer for fission yeast\n\n2015-10-19\n\nA new genetics primer, aimed at researchers interested in using fission yeast as a model system, has recently been published. The primer includes a brief history of fission yeast research, an introduction to available genetic tools, and the use of PomBase for data analysis\n\nHoffman CS, Wood V, Fantes PA. (2015) An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System. Genetics 201:403-423. PMID:26447128 DOI:10.1534/genetics.115.181503\n\nPomBase data update; viability summary correction alert\n\n2015-09-28\n\nWe have updated the data available on the PomBase web site to include manual curation through September 6, 2015.\n\nErrors in the previous FYPOviability.tsv file have been corrected, and we recommend that all users update this file, especially those who downloaded it earlier in September 2015.\n\nPomBase data update with multi-allele phenotypes\n\n2015-09-03\n\nWe have updated the data available on the PomBase web site to include manual curation through August 13, 2015, including 300 community-curated publications.\n\nPomBase gene pages now include multi-allele phenotype annotations (i.e. phenotypes of double mutants, triple mutants, etc.). New sub-sections of the gene pages display multi-allele phenotypes at the population and individual cell level, paralleling the organisation of the single allele phenotype display. Compact and full views are available; both show phenotypes with the relevant genotypes and the alleles that make them up, and the full view adds details for evidence, expression, conditions, and references.\n\nThe genome browser now includes data tracks for two more publications:\nDNA polymerase usage from:\nDaigaku Y, Keszthelyi A, Müller CA, Miyabe I, Brooks T, Retkute R, Hubank M, Nieduszynski CA, Carr AM. 2015. A global profile of replicative polymerase usage. Nat Struct Mol Biol. 2015 Mar;22(3):192-8. doi: 10.1038/nsmb.2962 PMID:25664722\nPromoters and transcription start sites from:\nLi H, Hou J, Bai L, Hu C, Tong P, Kang Y, Zhao X, Shao Z. 2015. Genome-wide analysis of core promoter structures in Schizosaccharomyces pombe with DeepCAGE. RNA Biol. 2015;12(5):525-37. doi: 10.1080/15476286.2015.1022704 PMID:25747261\n\nCodon adaptation index (CAI) values are now included in the Protein Properties section of the gene pages and in the downloadable PeptideStats.tsv file. A file of amino acid composition data is also available from the FTP site and the Protein Datasets page.\n\nThe gene page section that was formerly misnamed “species distribution” is now called “taxonomic conservation”.\n\nPomBase data update 2015-06-16\n\n2015-06-16\n\nWe have updated the data available on the PomBase web site to include manual curation through May 26, 2015, including 270 community-curated publications. See you at Pombe 2015 in Kobe!\n\nCanto downtime & new version\n\n2015-05-26\n\nCanto, PomBase’s literature curation tool, will be unavailable for approximately 3 weeks starting at 12:00 midnight UK time (BST) tonight, 27 May 2015, while we deploy an upgraded version.\nThe upgraded Canto will feature an entirely new interface for annotating multi-allele phenotypes and the corresponding genotypes, as well as improved workflows for single-allele phenotypes, GO, etc. All existing annotations will be retained, and users can resume curation using the new and improved features in any unfinished sessions when Canto is back online.\nWe will announce when the new version of Canto is released to the public.\n\nPomBase data update 2015-05-26\n\n2015-05-26\n\nWe have updated the data available on the PomBase web site to include manual curation through May 8, 2015, including 265 community-curated publications.\n\nPombe 2015 travel fellowships\n\n2015-04-23\n\nApplications are now being accepted for fellowships to provide financial support for students and postdocs attending the 8th International Fission Yeast Meeting in Kobe, Japan. To apply, follow the instructions sent to the pombase mailing list. The deadline is may 17, 2015 (same as the registration deadline).\n\nPomBase data update 2015-04-19\n\n2015-04-19\n\nWe have updated the data available on the PomBase web site to include manual curation through April 7, 2015, including 260 community-curated publications.The Advanced Search now supports queries for proteins with a specified number of transmembrane domains.\n\nPombe 2015 poster abstract deadline extended\n\n2015-04-19\n\nThe abstract submission deadline for the 8th International Fission Yeast Meeting in Kobe, Japan has been extended until midnight Friday, April 24 for posters only. Registration is open until May 17.\n\nPombe 2015 abstract deadline approaching\n\n2015-04-09\n\nAbstracts are due on Sunday, April 19, 2015 for the 8th International Fission Yeast Meeting in Kobe, Japan. Registration will remain open until May 17, but the abstract submission deadline cannot be extended.\n\nPomBase data update 2015-03-23\n\n2015-03-23\n\nWe have updated the data available on the PomBase web site to include manual curation through March7, 2015, including 250 community-curated publications.The autocomplete feature of the Advanced Search ontology term filter has been improved with respect to response time and relevance of suggested terms.\n\nPombe 2015 registration now open\n\n2015-02-26\n\nRegistration for Pombe 2015: 8th International Fission Yeast Meeting is now open at the conference web site, https://amarys-jtb.jp/web/Pombe2015/index.html\n\nThe registration deadline is 17 May 2015.\n\nThanks to Yasushi Hiraoka for this item.\n\nPomBase data update 2015-02-16\n\n2015-02-16\n\nWe have updated the data available on the PomBase web site to include manual curation through February 2, 2015, including 245 community-curated publications. On the gene pages, the interaction tables now provides a bit of descriptive text for each annotation, indicating the nature and direction of the interaction.\n\nPomBase data update 2015-01-26\n\n2015-01-26\n\nWe have updated the data available on the PomBase web site to include manual curation through January 12, 2015, including 240 community-curated publications. The gene page Phenotype section now features a compact default display. A downloadable “viability summary” data file is now available. The PomBase BLAST server has incorporated interface changes made Ensembl-wide.\n\nNew compact GO annotation display\n\n2014-12-10\n\nTo make the Gene Ontology (GO) annotations easier to read on PomBase gene pages, we have introduced a new, streamlined display that presents just the essentials. The summary shows the term name (hyperlinked to the ontology term page), the count of genes annotated to the term, and any annotation extensions. All of the previously visible annotation details are still available – simply click the “Summary” button to switch to the “Full” view. Or click the “+” and “-” icons to expand or collapse the annotation to a single term.\n In addition, the top of the Biological Process table now lists any GO slim terms applicable to the gene.\n\nesyN network visualizations in PomBase\n\n2014-12-10\n\nPomBase has implemented network visualisations for fission yeast in esyN, using data curated by BioGRID and PomBase. esyN is a web-based tool for building, sharing, and viewing network data developed by Dan Bean and Giorgio Favrin in the Cambridge Systems Biology Centre, University of Cambridge, UK.\nOn gene pages, we have links to gene-specific interaction networks in esyN in the table headers of the Interactions sections:\n\n-  The Genetic Interactions section links to all interactions centred on the gene and curated in BioGRID\n-  The Physical interactions section has links to two datasets:\n -  All physical interactions curated in BioGRID for the gene\n -  Interactions for the gene in the PomBase High Confidence Physical Interaction Network (HCPIN)\n\nWe also have esyN links on the GO Slim page and on ontology term pages for GO Slim biological process terms. Each GO Slim term links to the HCPIN physical interaction network in esyN (for example, see the “regulation of mitotic cell cycle” network).\n\nPomBase data update 2014-11-12\n\n2014-11-12\n\nWe have updated the data available on the PomBase web site to include manual curation through October 27, 2014, including 225 community-curated publications. The gene page Phenotype section now includes data from the high-throughput microscopy analysis of viable deletion mutants reported in:\nGraml V, Studera X, Lawson JL, Chessel A, Geymonat M, Bortfeld-Miller M, Walter T, Wagstaff L, Piddini E, Carazo-Salas RE. A Genomic Multiprocess Survey of Machineries that Control and Link Cell Shape, Microtubule Organization, and Cell-Cycle Progression. Dev Cell. 2014 Oct 27;31(2):227-39. doi: 10.1016/j.devcel.2014.09.005 PMID:25373780. Links to the accompanying SYSGRO resource have been added to the External References section of the gene pages.\n\nThe genome browser now includes tracks for intron branch point data from:\n\nBitton DA, Rallis C, Jeffares DC, Smith GC, Chen YY, Codlin S, Marguerat  S, Bähler J. LaSSO, a strategy for genome-wide mapping of intronic  lariats and branch points using RNA-seq. Genome Res. 2014 Jul;24(7):1169-79. doi: 10.1101/gr.166819.113 PMID:24709818.\n\nWe have greatly improved search results for GO and FYPO annotations: both now follow more relationship types within the ontology to retrieve genes annotated to a term. The PomBase GO search now includes the regulates relationships, so its search results are consistent with those in the GO Consortium’s AmiGO browser. The FYPO search now uses has_part, has_output, and output_of as well as is_a and part_of. The Phenotype section now includes a highlighted sub-header that indicates whether a deletion mutant is viable or inviable. A file of protein complex subunits is available for download, and numerous smaller improvements have been made in the gene pages and static pages.\n\nPomBase data update 2014-09-16\n\n2014-09-16\n\nWe have updated the data available on the PomBase web site to include manual curation through August 30, 2014. Community curation now covers over 200 papers.\n\nPomBase data update 2014-08-18\n\n2014-08-18\n\nWe have updated the data available on the PomBase web site to include manual curation through August 8, 2014. Community curation now covers over 190 papers. Gene pages now include links to the S. pombe PeptideAtlas, a database of peptides identified in tandem mass spectrometry proteomics experiments.\n\nPomBase data update 2014-07-17\n\n2014-07-17\n\nWe have updated the data available on the PomBase web site to include manual curation through July 8, 2014. The gene pages also now display protein modification data from an additional large-scale dataset:\n\nKoch A, Krug K, Pengelley S, Macek B, Hauf S. 2011. Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast. Sci Signal. 4(179): rs6 doi: 10.1126/scisignal.2001588 PMID:21712547\nWe have also made corrections to some residue positions affected by sequence updates in one of the modification datasets we added last month:\n\nCarpy A, Krug K, Graf S, Koch A, Popic S, Hauf S, Macek B. 2014. Absolute proteome and phosphoproteome dynamics during the cell cycle of fission yeast. Mol Cell Proteomics. 2014 Apr 23. [Epub ahead of print] PMID:24763107\n\nPomBase data update 2014-07-08\n\n2014-07-08\n\nWe have updated the data available on the PomBase web site. The data now includes manual curation through June 6, 2014. In other improvements, a downloadable file of intron sequence data (FASTA format) is now available, and phenotypes are now included in the Target Of section on gene pages.\n\nThe gene pages also now display protein modification data from two large-scale datasets:\n\n-  Wilson-Grady JT, Villén J, Gygi SP. 2008 .Phosphoproteome analysis of fission yeast. J Proteome Res. 2008 Mar;7(3):1088-97. doi:10.1021/pr7006335. PMID:18257517\n-  Carpy A, Krug K, Graf S, Koch A, Popic S, Hauf S, Macek B. 2014. Absolute proteome and phosphoproteome dynamics during the cell cycle of fission yeast. Mol Cell Proteomics. 2014 Apr 23. [Epub ahead of print] PMID:24763107\n\nLink updated 2021-02-04\n\nGene Ontology publication on annotation extensions\n\n2014-06-29\n\nPomBase was an early adopter of annotation extensions, which add spatial, temporal, or substrate/target details to GO annotations. The GO Consortium has now published a paper describing its implementation of annotation extensions, in which PomBase examples and its gene page display figure prominently:\n\nHuntley, R.P. et al. (2014) A method for increasing expressivity of Gene Ontology annotations using a compositional approach. BMC Bioinformatics 2014, 15:155. doi:10.1186/1471-2105-15-155 PMID:24885854\n\nPomBase data update 2014-05-15\n\n2014-05-15\n\nWe have updated the data available on the PomBase web site. The data now includes manual curation through April 28, 2014. Transcriptome data from Margeurat et al (2012) is now available as Ensembl Browser tracks.\n\nThank you to all who have done, or are doing, paper curation in Canto. Over 159 community-curated papers are now included in PomBase.\n\nThere are a number of routes to accelerate your data into PomBase, (either through community curation, or by supplying HTP sequence, modification or phenotype data in one of our specified formats), see http://www.pombase.org/submit-data for more details.\n\nAs usual, please don’t hesitate to alert us of any other problems with data or site performance, or if you have any questions.\n\nSincerely yours,\nThe PomBase Staff\n\nPomBase data update 2014-03-20\n\n2014-03-20\n\nData on the PomBase web site now includes manual curation through February 24, 2014. Human orthologs that went missing from gene pages have been restored, and other small improvements have been made to gene pages. Community curation now covers over 130 publications.\n\nPomBase data update 2014-02-20\n\n2014-02-20\n\nWe have once again updated the data available on the PomBase web site. The data now includes manual curation through January 10, 2014, and covers over 100 papers that have been curated in Canto by community members. We again thank all who have contributed curation via Canto.\n\nWe have made some improvements to the gene pages. Highlights:\n\n-  The Sequence section now has links to NCBI BLAST as well as Ensembl BLAST.\n-  The External References section now links to the Pomb(A) polyadenylation viewer.\n\nIn the genome browser, new data tracks are now available for data from these publications:\n\n-  Rhind N, [and many more]. 2011. Comparative functional genomics of the fission yeasts. Science 332(6032):930-6. doi: 10.1126/science.1203357. PMID:21511999\n-  Schlackow M, Marguerat S, Proudfoot NJ, Bähler J, Erban R, Gullerova M. 2013. Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe. RNA. 19(12):1617-31. doi:10.1261/rna.040675.113. PMID:24152550\n-  Soriano I, Quintales L, Antequera F. 2013. Clustered regulatory elements at nucleosome-depleted regions punctuate a constant nucleosomal landscape in Schizosaccharomyces pombe. BMC Genomics. 14:813. doi:10.1186/1471-2164-14-813. PMID:24256300 (partial data;  remainder coming in the next update)\n-  Xu J, Yanagisawa Y, Tsankov AM, Hart C, Aoki K, Kommajosyula N, Steinmann KE, Bochicchio J, Russ C, Regev A, Rando OJ, Nusbaum C, Niki H, Milos P, Weng Z, Rhind N. 2012. Genome-wide identification and characterization of replication origins by deep sequencing. Genome Biol. 13(4):R27. doi:10.1186/gb-2012-13-4-r27. PMID:22531001\n\nNow that more data tracks are available, we have added some categories to the track configuration section to improve organization. Additional documentation is in preparation, and will be announced here when available.\nGenome sequences for additional Schizosaccharomyces species (S. japonicus, S. octosporus, and S. cryophilus) have recently become available in Ensembl Fungi, and the PomBase genome browser now includes comparative genomics data, with a view of region comparisons between each new genome and S. pombe.\n\nHuman ortholog data correction coming next month\n\n2014-02-19\n\nWe are about to release a data update for PomBase. Please note that there is still a problem with the human orthologs, as originally described on this list in mid-December (see archived message at http://listserver.ebi.ac.uk/pipermail/pombelist/2013/003926.html). We will correct this problem in the next PomBase release, and apologise for any inconvenience in the meantime.\n\nPomBase data update 2013-12-08\n\n2013-12-08\n\nWe have updated the data available on the PomBase web site to include manual curation through November 11, 2013. We now have future meetings available as a calendar or a list. The FAQ and some documentation pages have also been updated.\n\n2021-08-18: Updated to remove out-of-date links (events are now listed only as news items).\n\n2013 meeting mini-reviews published\n\n2013-11-24\n\nA series of mini-reviews, which were invited in association with the International Fission Yeast Meeting in London, have now been published in Biochemical Society Transactions: http://www.biochemsoctrans.org/bst/041/6/default.htm#c\n\n(Thanks to Jürg Bahler for this item)\n\nPomBase survey results available\n\n2013-11-20\n\nThe 2013 PomBase user survey closed at the end of October, and the results are available here (PDF at FTP site). Some highlights have been sent to the pombe mailing list. Many thanks to all who completed the survey.\n\nLink updated 2021-02-04\n\nNew “Target Of” gene page section\n\n2013-10-27\n\nWith the October 2013 update, gene pages now include “Target Of” annotations, which describe genes that affect the gene of interest. These annotations are essentially the reciprocal of ontology annotation extensions. Each “Target Of” annotation includes a relationship that indicates how the genes are connected, the name and product of the second gene, and a reference. Genes listed under “Target Of” may include upstream regulators or enzymes that modify the product of the gene of interest. For example, the “Target Of” annotations for cdc2 indicate that it is a substrate of, and regulated by, the kinase Wee1 and the phosphatase Cdc25 (among others). At present, “Target Of” data includes annotations derived from GO annotation extensions. We will soon extend it to include data from phenotype annotation extensions.\n\nPomBase data update 2013-10-21\n\n2013-10-21\n\nThe PomBase web site has been updated and now includes manually curated data through October 6, 2013. The number of community-curated papers continues to increase, ensuring that PomBase gene pages contain complete and up-to-date information. We are also pleased to announce that data tracks are now available in the genome browser for data from these two publications:\n\n-  Woolcock KJ, Gaidatzis D, Punga T, Bühler M. 2010. Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe. Nat Struct Mol Biol. 2011 Jan;18(1):94-9. doi: 10.1038/nsmb.1935 PMID:21151114\n-  Mata J. 2013. Genome-wide mapping of polyadenylation sites in fission yeast reveals widespread alternative polyadenylation. RNA Biol. 2013 Aug 1;10(8):1407-14. doi: 10.4161/rna.25758 PMID:23900342\n\nPomBase User Survey open\n\n2013-09-18\n\nTo guide current and future development, PomBase is now conducting a user survey, where we invite the fission yeast research community and any other PomBase users to evaluate the resources provided so far and comment on future priorities. The survey should take about 10 minutes to complete. Thank you for your participation!\n\nhttps://www.surveymonkey.com/s/NDM2BQX\n\nPomBase data update 2013-09-15\n\n2013-09-15\n\nWe have once again updated the data available on the PomBase web site. The data now includes manual curation through August 11, 2013. We are particularly pleased to note that this update includes annotations from several dozen papers curated by the S. pombe community. Many thanks to all who have done, or are doing, paper curation in Canto.\nWe also have an updated version of the S. pombe/human ortholog table available upon request.\n\nSend HTP data to PomBase\n\n2013-08-18\n\nAt the pombe 2013 meeting in London, PomBase staff received numerous requests display various published data, such as gene expression, histone modifications, etc. in the genome browser. To provide this, we now invite pombe researchers to send data: If you have published any high-throughput experiments that produced data  that can be associated with genome sequence coordinates, and thereby displayed as tracks on the PomBase genome browser, please fill out the HTP Data Submission Form. We can also accept large sets of phenotype data via the Phenotype Data Submission Form. If you have any problems or questions, contact us via the PomBase Helpdesk at any time.\n\nConnecting With PomBase\n\n2013-07-29\n\nTo complement the mailing list and twitter (@PomBase) it is now possible to follow the activities of PomBase and interact with other members of the pombe community via the new LinkedIn Group and Google+.\n\nLinks to these are also available from the front page of the PomBase.org site.\n\npombelist has moved\n\n2013-07-21\n\nUpdate: This item dates from July 2013, and the links in it no longer work. \\ Please see the Fission Yeast Community page for the current mailing list link. \\ (2020-02-18)\n\nThe pombe community mailing list, pombelist, has migrated from the Wellcome Trust Sanger Institute and is now hosted by EBI. The new address is pombelist@ebi.ac.uk (please note that the old address no longer works, and will generate an automatic notification including the new address). The link to subscribe has also been updated, and the entire archive is available at the new location.\n\nPomBase website update\n\n2013-07-18\n\nWe’d like to highlight a few improvements we’ve just made to the PomBase website. Most of the changes affect the gene pages:\n\n-  The basic information display at the top of each gene page is more compact.\n-  For ontology annotations, the number of genes annotated is now shown, in a column labeled “Count” (also, changes behind the scenes involving this data mean that pages should load faster).\n-  Annotation extensions for GO are displayed using human-friendly text instead of internal “relation” labels.\n-  The Quick Links box can now be collapsed and expanded by clicking its header.\n-  Display of modification annotations using PSI-MOD is improved.\n\nIn addition, the Motif Search output now includes standard gene names and product descriptions. As we noted in a separate message, CDS coordinate files are once again available from the Downloads, with accurate and up-to-date data.\n\nPomBase launches community curation\n\n2013-06-23\n\nAt the pombe 2013 conference in London, PomBase officially launched its community curation initiative, which allows researchers to contribute publication-based annotations directly to the database. PomBase curators invite lab heads by individual email to curate newly published papers, providing links to the online curation system and its documentation. Researchers can also initiate curation of any older fission yeast publication in PubMed. Community curation uses the open-source online tool Canto.\n\nPomBase data update 2013-06-20\n\n2013-06-20\n\nPomBase data now includes manual curation through June 9, 2013, and represents complete annotation for 664 publications (as well as partial curation of many more). A highlight of this month’s literature curation update is the addition of over 9400 phenotype annotations, representing about 95% of the phenotype data from the recently published genome-wide study of cell cycle and cell morphology (Hayles et al. Open Biology May 2013; PMID:23697806). We have also improved the display of allele details for phenotype annotations. Other changes include better support for gene synonyms in the simple search, regular updates to the UTR data files, and a number of minor adjustments to external links in the annotation data tables and the external references section.\n\nPomBase data update\n\n2013-05-20\n\nWe have updated the data available on the PomBase web site. The data now includes manual curation through 13 May, 2013.\n\nGeneDB S. pombe decommissioned\n\n2013-05-13\n\nAs of 14 May 2013, the old GeneDB database for S. pombe is no longer available. This resource consisted of static web pages, was not updated after March 2012, and not supported by an underlying relational database. The PomBase site fully supersedes GeneDB S. pombe, and provides improved infrastructure that will meet the current and future needs of the fission yeast community. Please e-mail the helpdesk if you cannot find a replacement for any GeneDB functionality in PomBase.\n\nQuantitative gene expression data available in PomBase\n\n2013-05-07\n\nWe have extended the Gene Expression section of each gene page to support the display of quantitative expression data, and are now showing data from two publications:\n\n-  Marguerat S, Schmidt A, Codlin S, Chen W, Aebersold R, BählerJ. 2012. “Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.” Cell 151:671-683.\n-  Wu JQ, Pollard TD. 2005. “Counting cytokinesis proteins globally and locally in fission yeast.” Science 310:310-314.\n\nWe will also soon refine the display of the new expression data, and can add more datasets upon request. We thank Sam Marguerat for preparing the data from both papers for inclusion in PomBase.\n\nWe have also updated the PomBase site to include manual curation through April 4, 2013, and we have updated the “all gene names” file on the PomBase ftp site. The new file is available at\nhttps://www.pombase.org/data/names_and_identifiers/gene_IDs_names.tsv\n\nLink updated 2021-02-04\n\nCarl Singer Foundation Established\n\n2013-04-11\n\nCarl Singer, who was an integral part of the yeast research community for many years, passed away on February 8, 2013. Throughout his career, Carl supported yeast research both with his engineering expertise and with his good cheer. In tribute to Carl, the Singer family has now set up The Carl Singer Foundation, a charitable foundation dedicated to supporting scientific education in the field of yeast genetics. Questions about the foundation may be directed to Harry Singer at harry [at] thecarlsingerfoundation.org.\nCarl’s family would be happy to receive memories of Carl’s life at regards [at] singerinstruments.com.\n\nH/T SGD\n\nPombe 2013: registration & abstracts by Mon 8th April\n\n2013-04-02\n\nDear Pombe Fans,\n Please remember the imminent deadline (Monday 8th April) to register and submit abstracts for Pombe 2013: http://events.embo.org/13-pombe\n Abstracts are also required from all who have already been invited to talk.\n And do book your accommodation if you haven't yet done so.\n More details are in previous email forwarded below.\n Cheers,\n -Jürg & Jacky\n From: On Behalf Of Bahler, Jurg\n Sent: 18 March 2013 17:49\n To: pombelist at sanger.ac.uk\n Subject: [Pombelist] Pombe 2013: Accommodation, registration & abstracts\n Dear Pombe Afficionados,\n Only three weeks left to register and submit abstracts for Pombe 2013, by Monday 8th April: http://events.embo.org/13-pombe\n Speakers for 10 plenary talks and all workshop talks will be selected from abstracts, and there will be attractive poster prizes.\n Payment is only requested after registration, by 10th May.\n Important: if you require accommodation, please do book this real soon now. Especially the most cost-effective student accommodation (comfortable, with private bathrooms) may not be available much longer, as it will be put on general sale shortly. Both hotels and student accommodation will sell out in June, so you have to arrange it now. Information on accommodation is available here: http://events.embo.org/13-pombe/application.html\n We will provide a number of free registrations for which you can apply during online registration (a few of which are reserved for student members of The Genetics Society: you become eligible if you join them now). The meeting is also supported by the Biochemical Society, so if you are, or become, a member you can apply to them for student bursaries or, if you have been a member for at least 1 year, also for travel grants.\n We highly appreciate all the generous contributions from our sponsors so far:\n Platinum: EMBO\n Gold: Biochemical Society, Genetics Society, Formedium, Sunrise Science Products, Singer Instruments, F1000Research, PomBase/Wellcome Trust\n Silver: MDPI - Open Access Publishing, Hybrigenics, Infors, Life Technologies, Bioneer\n Bronze: Nature Communications, m2p labs, Imsol, Open Biology\n We look very much forward to welcoming you in London this June!\n All the best,\n -Jürg & Jacky\n\nData update on PomBase web site\n\n2013-04-01\n\nWe have once again updated the data available on the PomBase web site. The data now includes manual curation through March 6, 2013.\nWe now expect to be able to update PomBase data every month, and will soon have an automated pipeline in place. We thank all of you for your patience during the long months when updates were infrequent.\nYou should also see a few small improvements in the site:\n\n-  Ontology term pages now display the text definition for each term.\n-  FASTA sequence retrieval should be quicker, and less likely to time out, for large gene lists.\n-  There has been some tidying of the display of “extension” data for GO and phenotype annotations.\n\nLast month we noted an intermittent problem with the “Reference” column display in the data tables. The occurrence of this problem should now be greatly reduced, so please let us know if you see it recurring.\nAs usual, please don’t hesitate to alert us of any other problems with data or site performance, or if you have any questions.\n\nSpeed improvements and new data on PomBase web site\n\n2013-03-01\n\nWe have updated the data available on the PomBase web site. The data now includes manual curation through December 17, 2012, and reflects complete curation of an additional 70 papers.\nWe have also made some improvements “under the hood” that should make gene page loading much faster. Please let us know if you have any problems with gene pages loading slowly or incompletely, whether or not you have reported issues in the past.\nWe are aware that there is an intermittent problem with the “Reference” column display in the data tables – sometimes a PubMed ID appears instead of an author name and year. This problem will be fixed as soon as possible. Please alert us if you notice anything else odd or wrong.\n\nNew data and new features on PomBase web site\n\n2012-11-06\n\nWe are pleased to announce that we have updated both data and web site features for PomBase.\n\nMost importantly, we have added new data types, and upgraded the gene pages to display them.\n\nWe have also added more annotations of existing data types, bringing the web site content up to September 11, 2012. The new annotations include the first contributions to come in via the new community curation system, and we thank the researchers who are participating in the initial phase of community curation.\n\nNew annotation types:\n\n-  Phenotype annotations now use the Fission Yeast Phenotype Ontology (FYPO), and include allele details, expression levels, and experimental conditions. With FYPO, more detailed phenotypes can be described, and links between terms for related phenotypes support improved phenotype searches.\n-  Many GO annotations now include “annotation extensions” that provide additional specificity. For example, extensions may capture the substrate of a catalytic activity, the cell cycle phase during which a function or process occurs, or any of several other types of supporting information for the annotation. Annotation extensions are described in more detail below.\n\nYou can see these new data types on many gene pages, such as cdc2 or pka1.\n\nNew web site features:\n\n-  Annotation display - Gene page GO and phenotype displays have been revamped to show new annotation types described above.\n-  Ontology term pages - Each ontology term ID now links to pages with information about the term and lists of genes annotated to it.\n-  Ontology graph links - GO and phenotype annotation sections now include links to graphical ontology displays in the genome browser.\n-  Sequence highlighting - Sequence download now offers an option to show colour highlighting of regions such as UTRs, introns and exons.\n-  Versions - Each gene page now shows the current data version in the format PomBase:x.y, where x is the Ensembl Genomes (EG) version, and y is the Chado version. The sequence, and sequence feature locations, remain stable within any EG version, whereas annotations change with each Chado update.\n-  Protein family information is now included in the Protein Features gene page section.\n-  The Protein Feature section includes a link to the Pfam entry for a protein.\n-  Transcript source data (e.g. for UTR coordinates) is now displayed in the Transcript Features section.\n-  A Documentation page contains links to relevant portions of the Ensembl Genomes documentation. (More documentation will be added over the coming months.)\n\nWhat are annotation extensions?\n\nAnnotation extensions are a form of supporting data that can be added GO annotations (or other ontology annotations) to capture additional details not provided by the ontology term itself.\n\nThe information in GO annotation extensions encompasses several effector-target relationships, such as\n\n-  localisation dependencies\n-  substrates of functions, e.g. targets of a protein kinase – see the has_substrate extensions on Cdc2’s “protein serine/threonine kinase” (GO:0004674) annotations\n-  activators and inhibitors\n-  regulation targets of signalling pathways or transcription factors\n\nAdditional extensions describe spatial and temporal aspects of processes. For example, several S. pombe annotations now include extensions that indicate in which phase of the cell cycle a gene product is found in a cellular component or involved in a process – see the pka1 annotations to “nucleus” (GO:0005634) and “cytoplasm” (GO:0005737).\n\nYou may also find the GO wiki page on annotation extensions informative, although it is primarily aimed at curators.\n\nAnnotation extensions can also be used with phenotype annotations. The most common usage of phenotype annotation extensions is to capture which gene, protein, etc. was used in an assay. For example, the sam5 (G441E) mutation of pka1 causes nuclear accumulation of Ste11. This is represented by annotation to the ontology term “nuclear protein accumulation” (FYPO:0000255), with the extension “assayed_using(PomBase:SPBC32C12.02)”. Extensions can also indicate expressivity or penetrance for a phenotype.\n\nPomBase web site fully live\n\n2012-07-01\n\nNote (2023-06-09): This is an archived news item about PomBase V1. See the documentation page to learn new Advanced search in PomBase V2.\n\nWe are pleased to announce that the PomBase web site, www.pombase.org, is now fully live; the preview phase has ended. The site has been updated with an assortment of new features, datatypes, and bug fixes.\n\nMore recent data, reflecting additions and changes through March 20, 2012, are now available on gene pages and in search results.\n\nThe updated site features a Gene List Search that provides behavior equivalent to GeneDB’s List Download. You can now type or paste lists into the Gene Systematic IDs and Gene Names filters, and use the Query History to combine a gene list search with other search options. For convenience, there is a direct link to a search page pre-configured to accept a list of systematic IDs available in the Find menu, on the Find page, and here: http://www.pombase.org/spombe/query/builder?filter=12\n\nThe Advanced Search also now offers:\n\n-  options to search GO, FYPO, and other ontologies by term name or ID;\n-  autocomplete for ontology term name search;\n-  ability to search for genes in a region, such as centromeres or telomeres;\n-  improved organization of filter selections.\n\nWe have also fixed a Sequence Download error reported by some users, so that the “CDS”, CDS + UTRs”, and “CDS + UTRs + Introns” options now retrieve the correct sequences.\nIn addition, numerous minor improvements have been made. Please send any questions or comments on the PomBase web site to us at <helpdesk@pombase.org>.\n\nPomBase preview launch\n\n2011-11-27\n\nA preview of PomBase, the new model organism database for the fission yeast Schizosaccharomyces pombe, has been announced to the S. pombe community for testing and feedback. For more on PomBase, see the NAR Database Issue paper (PubMed abstract) or contact the PomBase staff.\n\nPomBase NAR paper published online\n\n2011-10-27\n\nA paper describing PomBase has been published online will be included in the 2012 Database Issue of Nucleic Acids Research. Abstract and open access full text are available.\n\nGeneDB (S. pombe) now uses the latest release of the Pfam protein family database(25.0).\n\n2011-04-28\n\nSchizosaccharomyces Comparative Genome Paper Published\n\n2011-04-21\n\nA paper describing the major findings of the Schizosaccharomyces Comparative Genome Project was published today in Science Express and reported changes are included in GeneDB.\n\nFurther details are described in the pombe mailing list posts:\n\n-  Schizosaccharomyces Comparative Genome Paper Published\n-  Import of the fission yeast revisions from the Broad Institute comparative genome paper into GeneDB.\n\nGenome reappraisal reveals new genes and revised gene structures\n\n2011-02-01\n\nFurther information on the pombe mailing list.\n\nAnnotated transcription start and termination sites for fission yeast\n\n2011-01-31\n\nFurther details are available on the pombe mailing list.\n\nAnalysis of Fission Yeast Deletion Publication\n\n2010-05-15\n\nThe analysis of the fission yeast deletion collection is now published online in Nature Biotechnology.\n\nFunding for PomBase\n\n2010-02-28\n\nFunding was awarded by the Wellcome Trust for a fission yeast Model Organism Database, PomBase.\n\nFission yeast is one of the 12 key organisms of the reference genomes project\n\n2009-11-30\n\nFission yeast is one of the 12 key organisms of the reference genomes project. The goal of this project is to completely annotate twelve reference genomes so that those annotations may be used to effectively seed the automatic annotation efforts of other genome.\n\nGeneDB (S. pombe) now uses the latest update to Pfam, release 24.0\n\n2009-10-31\n\nGeneDB (S. pombe) now uses the latest update to Pfam, release 24.0 and 88.5% of fission yeast proteins now contain a match to at least one Pfam domain (increased from 83% in version 23).\n\nFission yeast in Ensembl Fungi\n\n2009-09-30\n\nThe fission yeast genome and annotation dataset is now available as part of Ensembl Fungi.\n\nGeneDB is now using Version 23 of the Pfam protein family database.\n\n2009-08-31\n\nGeneDB is now using Version 23 of the Pfam protein family database. A total of 4154 (83%) S. pombe proteins now have at least one Pfam domain or family assignment (compared to 76% for S. cerevisiae), the highest percentage coverage for any eukaryote.\n\nS. pombe GeneDB now includes “deep links” to the Biological General Repository for Interaction Datasets (BioGRID)\n\n2008-11-30\n\nS. pombe GeneDB now includes “deep links” to the Biological General Repository for Interaction Datasets (BioGRID) interaction datasets from the ‘Database Cross References’ section of the individual Gene Pages.\n\nGlobal sequence and chip study examines eukaryotic transcription\n\n2008-04-30\n\nDynamic repertoire of the fission yeast transcriptome reveals: 94% of the genome is transcribed; extensive variation in different stages and conditions; global and condition-specific coupling between splicing efficiency and transcription; confirms the majority of introns; refines ~75 gene structures; identifies 453 new transcripts 26 of which were predicted to code for proteins.\n\nThe h- mating type region has been provided\n\n2008-01-31\n\nThe h- mating type region has been provided by Xavier Marsellach and Lorena Aguilar.\n\nBaumann and Zakian labs identify telomerase RNA\n\n2007-12-31\n\nBaumann and Zakian labs identify elusive telomerase RNA (PMID:18157152 and PMID:18157149)\n\nWellcome Trust Advanced Course ’Genome-wide approaches with fission yeast\n\n2007-09-30\n\nWellcome Trust Advanced Course ‘Genome-wide approaches with fission yeast’ held in Hinxton.\n\n4th International Fission Yeast Meeting\n\n2007-05-31\n\n4th International Fission Yeast Meeting held in Copenhagen.\n\nGeneDB representation of the fission yeast data moved from contigs to chromosomes\n\n2006-12-31\n\nGeneDB representation of the fission yeast data moved from contigs to chromosomes. See the pombelist archive for details.\n\nYeast Special Issue from the 2006 European Fission Yeast Meeting\n\n2006-09-30\n\nThe October issue of the journal Yeast is a fission yeast special issue containing 13 articles and reviews commissioned as a result of the European Fission Yeast Meeting, which are FREE to download.\n\nThe first fission yeast whole proteome localization study is now published\n\n2006-06-30\n\nThe first fission yeast whole proteome localization study is now published: Matsuyama A. et al (2006): ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotech 24, 841-7.\n Fission yeast database survey\n\n2006-04-30\n\nThe fission yeast database survey is now closed. You can view the survey results here.\n\nEuropean Fission Yeast Meeting\n\n2006-03-17\n\nThe European Fission Yeast Meeting (16th-18th March 2006) and The Fission Yeast Bioinformatics workshop (15th - 16th Mar 2006) both took place at the Wellcome Trust Genome Campus in Hinxton (Cambridge, UK).\n\nComparative Genomics of Eukaryotic Microorganisms\n\n2005-11-16\n\nComparative Genomics of Eukaryotic Microorganisms:\nEukaryotic Genome Evolution, Approaches with Yeasts and Fungi\n\nThis conference took place from 12th-17th November 2005 in Sant Feliu de Guixols, Spain. Full details can be found here.\n\nSecond East Coast Regional pombe Meeting\n\n2005-11-12\n\nSecond East Coast Regional pombe Meeting\nThis meeting took place from November 11-13, 2005 in Miami Beach, Florida.\n\nGeneral Repository for Interaction Datasets\n\n2004-08-31\n\nA project to record published genetic and physical interactions is underway with Mike Tyers and the GRID group at Toronto.\n\nThe Third International Fission Yeast Meeting\n\n2004-08-29\n\nThe meeting was held at UC San Diego on August 24-29, 2004.\n\nMethods Volume 33 Issue 3\n\n2004-04-30\n\nThis issue of Methods includes 11 papers for fission yeast protocols including DNA damage checkpoint assays, cell wall analysis, TAP, nuclear envelope integrity assays, GFP imaging, TS mutant creation and plasmid use and construction. See the Methods site for details of the papers including PMIDs.\n\n2021-08-18: Updated to remove out-of-date link.\n\nRecent Genome wide surveys\n\n2003-10-31\n\nCorrelations Between Gene Expression and Gene Conservation in Fission Yeast. Mata J, Bahler J. Genome Res. 2003 Nov 12 PMID:14613978\nFELINES: a utility for extracting and examining EST-defined introns and exons. Drabenstot SD et al Nucleic Acids Res. 2003 Nov 15;31(22):e141. PMID:14602934\nGenome-wide distribution of DNA replication origins at A+T-rich islands in Schizosaccharomyces pombe. Segurado M, De Luis A, Antequera F. EMBO Rep. 2003 Nov;4(11):1048-53. Epub 2003 Oct 17. PMID:14566325\nRetrotransposons and their recognition of pol II promoters: a comprehensive survey… Bowen NJ et al Genome Res. 2003 Sep;13(9):1984-97. PMID:12952871\n\nThe ‘new’ fission yeast book is now published\n\n2003-08-31\n\nEgel, R., Copenhagen, Denmark (Ed.) The Molecular Biology of Schizosaccharomyces pombe Genetics, Genomics and Beyond ISBN:3-540-00693-1\n\nSchizosaccharomyces pombe Essential Genes: A pilot Study\n\n2003-02-28\n\nDecottignies A, Sanchez-Perez I, Nurse P Genome Res. 2003 Mar;13(3):399-406. PMID:12618370\n\nGlobal transcriptional responses of fission yeast to environmental stress\n\n2002-12-31\n\nChen D, Toone WM, Mata J, Lyne R, Burns G, Kivinen K, Brazma A, Jones N, Bähler J. Mol Biol Cell. 2003 Jan;14(1):214-29. PMID:12529438\n",
+      "content" : "\n\nThe improved nomenclature guidelines for fission yeast clade genes and alleles have been published in Genetics GSA. This update introduces nomenclature guidelines for noncoding RNA genes, a significant update to the allele and genotype nomenclature guidelines originally published in 1987. We took several steps to improve machine readability that will benefit the artificial intelligence/machine learning communities, and our own community curation program.\n\nLera-Ramírez et al. 2023, Revised fission yeast gene and allele nomenclature guidelines for machine readability, Genetics, 2023;, iyad143\n\n[“Revised fission yeast gene and allele nomenclature guidelines for machine readability”]\n",
+      "heading" : "Revised fission yeast nomenclature for genes and alleles",
+      "id" : "news/2023-09-30-nomenclature-paper"
+   },
+   {
+      "content" : "\n\nRevised fission yeast nomenclature for genes and alleles\n\n2023-09-30\n\nThe improved nomenclature guidelines for fission yeast clade genes and alleles have been published in Genetics GSA. This update introduces nomenclature guidelines for noncoding RNA genes, a significant update to the allele and genotype nomenclature guidelines originally published in 1987. We took several steps to improve machine readability that will benefit the artificial intelligence/machine learning communities, and our own community curation program.\n\nLera-Ramírez et al. 2023, Revised fission yeast gene and allele nomenclature guidelines for machine readability, Genetics, 2023;, iyad143\n\n[“Revised fission yeast gene and allele nomenclature guidelines for machine readability”]\n\nAccessing the list of genes from a paper\n\n2023-09-20\n\nIt’s now possible to view the list of genes associated with a paper, using a new link on the publication pages. The gene list can then optionally be sent to the Advanced Search.\n\n[Publication page, highlightling the new genes link]\n\nProtein feature viewer added to gene pages\n\n2023-07-27\n\nPomBase gene pages now include a protein feature widget. This tool shows protein features in the context of amino acid sequence. It includes:\n\n-  amino acid substitution positions\n-  Pfam domains\n-  protein modifications\n-  protein properties: low complexity regions, disordered regions, coiled coil regions and predicted trans-membrane domains\n\nHover over features for more information, such as allele descriptions and Pfam domain IDs.\n\n[Protein feature viewer widget - cdc15 gene page]\n\nFollow the “View all protein features …” link for a detailed view on the dedicated protein features page that includes:\n\n-  details of the individual amino acid substitution allele changes\n-  partial amino acid deletions\n\n[Protein feature viewer details page for cdc15]\n\nThanks to the team at RCSB PDB for providing the Open Source software used to implement this feature.\n\nReaction diagrams on term pages\n\n2023-06-19\n\nWhere available, we now show the reaction diagram from Rhea on GO function term pages. This feature is possible thanks to the great work of Rhea.\n\nSee the GO:0003849 term page for an example.\n\n[]\n\nCuration update - “nonsense mutation” merged into “partial amino acid deletion”\n\n2023-04-26\n\nWe have decided to merge the allele type “nonsense mutation” into “partial amino acid deletion”. This has mainly been driven by the fact that allele types that combine different variants require new types, such as “amino_acid_deletion_and_mutation”, “amino_acid_insertion_and_deletion”, etc. Otherwise, we would have ended up with many more types, and at the gene product level (which is what we describe in PomBase in phenotype interactions), both truncations are equivalent. In the next update, this allele type will not be available in Canto.\n\nIn any case, even if two alleles produce the same truncation, such as ase1-D13* or ase1Δ(13-731), they would still have separate entries in PomBase, and they may have different phenotypes. We are only assigning them the same allele type.\n\nIf for your analysis you need to make a distinction between the two using our allele dataset allele dataset, you can always check the “Allele description” field for the presence of the “*” character to tell whether an allele includes a nonsense mutation.\n\nExperimental structures from PDB on gene pages\n\n2023-02-22\n\nThe experimental protein structures from PDB are now embedded on the PomBase gene pages using Mol*. For example: lsm7/SPCC285.12 gene page\n\nIf you select the “PDB structures” view on a gene page, experimental structures will set as your default. AlphaFold predictions will be shown for genes where an experimental structure are not available.\n\nWe now also display the structures on the associated publication page. For example: PMID:31010807 Garg et al.\n\nTo help locate proteins with experimental protein structures (currently 375), we have added a new query option to the “Advanced search”, currently under “commonly used queries”: “Proteins with PDB structures”\n\n[PDB structures on the lsm7 gene page]\n\nAlphaFold protein structure on gene pages\n\n2023-02-02\n\nAlphaFold protein structure are now embedded on the PomBase gene pages. We hope to embed the experimental structures from PDB in the near future.\n\n[Example from the mvp1 gene page]\n\nRevised canonical 5’ UTRs\n\n2023-01-24\n\nWe have revised the curated 5’UTRs using Transcription Start Sites (TSS) data (in vegetative growth/ minimal media) from the Cap Analysis of Gene Expression (CAGE) data provided by Thodberg et al. All new gene structures were manually reviewed, around ~80 protein features had N-terminal coordinate revisions to align with TSS data.\n\nGlobal Core Biodata Resource status for PomBase\n\n2022-12-15\n\nWe are very pleased to announce that PomBase has been selected as one of the first Global Core Biodata Resource (GCBR) — a collection of 37 resources whose long term funding and sustainability is critical to life science and biomedical research worldwide. This accreditation recognizes PomBase as a primary knowledge base (adding value to data through expert curation) and as a crucial component of the research ecosystem. The candidate biodata resources were assessed against a series of rigorous criteria that included their scientific focus, the size and reach of their user communities, their quality of service, their governance, and their impact on global research.\n\nThank you to the entire community, especially the community curators who contribute regularly to our content, and our Scientific Advisory Board for their help and support.\n\nFor more information about the Global Biodata Coalition and PomBase’s new status, see the full press release.\n\nNext PombeTalks: Wednesday, December 14th\n\n2022-12-08\n\nThe next online PombeTalks will take place on Wednesday, December 14th. These talks are virtual seminars by and for the fission yeast community and friends.\n\n8:00 San Francisco; 11:00 NY; 16:00 London; 17:00 Paris; 20:30 Delhi, 23:00 Beijing; midnight Tokyo\n\nThis will be our last PombeTalks of 2022 before taking a winter break. The speaker will be:\n\n-  Kristi E. Miller\n “The fission yeast cell size control system integrates pathways measuring cell surface area, volume and time”\n\nIt will be followed by some sum up/ feedback about PombeTalks from the organizing committee.\n\nSurvey\n\nPlease help us improve PombeTalks even more by taking this quick survey\n\nZoom details\n\nTopic: PombeTalksS308 Zoom Meeting\nDate: Dec 14th\nMeeting ID: 975 0331 6190\nPassword: will be sent the day of the meeting\n\nSlack\n\nFor more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nQuerying by RNA length in the Advanced Search tool\n\n2022-12-07\n\nYou can now query the RNA length of genes (spliced or unspliced) under the “Transcripts and exons” query grouping in the Advanced search.\n\nYou can also add RNA sequence length as a field in tables downloaded from the query builder.\n\n[RNA length queries are available under the “Transcripts and exons” tab]\n\nGenetic Interaction annotation model updated\n\n2022-11-29\n\nWe have recently implemented an improved way to annotate and display genetic interactions so they are linked to phenotype annotations and alleles.\n\nPreviously, our Genetic Interaction annotations only mentioned the interacting genes and the type of genetic interaction. For example, if a strain with genotype asp1-H397A has the phenotype decreased acid phosphatase activity affecting activity of pho1, but this phenotype is suppressed when rhn1 is deleted in that strain, we would annotate that the genes asp1 and rhn1 are part of a Phenotypic Suppression interaction.\n\n[GI old format]\n\nWe continue to display interactions in this format by default (showing only genes and interaction type), but if you expand the annotation, you can view the associated genotypes and phenotypes.\n\n[GI new format]\n\nIn the revised Canto interface, you can only annotate a genetic interaction from the double mutant phenotype annotation (by clicking on add.., as shown below).\n\n[GI annotation in Canto]\n\nOf course, genetic interactions predating this update are not linked to phenotypes or genotypes, but we are hoping to auto-annotate several of those. We will also prioritise for update any interactions where community curators have provided these details in an annotation comment. Finally, a big shoutout to Ana Sanchez and Angad Garg from the Shuman lab, for testing the new interface in numerous recently curated publications. The examples provided here are from Sanchez et al. 2019. Go read it and see the annotations in PomBase.\n\nBest, The PomBase team\n\nNext pombeTalks: Wednesday, November 16th\n\n2022-11-11\n\nThe next online pombeTalks will take place on Wednesday, November 16th. These talks are virtual seminars by and for the fission yeast community and friends.\n\nNote that this session will happen earlier at:\nmidnight San Francisco; 03:00 NY; 08:00 London; 09:00 Paris; 13:30 Delhi, 16:00 Beijing; 17:00 Tokyo\n\nTalks this session:\n\n-  Wenfan Wei, University of Science and Technology of China\n “The Cdc42 GAP Rga6 promotes monopolar outgrowth of spores”\n\n-  Gaowen Liu, Shenzhen Institute of Synthetic Biology\n “Fusion eciency evolution to the deletion of an essential mating gene Prm1”\n\nZoom details\n\nTopic: PombeTalks S03E07 Zoom Meeting\nDate: Nov 16, 2022\nTime: midnight San Francisco; 03:00 NY; 08:00 London; 09:00 Paris; 13:30 Delhi, 16:00 Beijing; 17:00 Tokyo\nMeeting ID: 932 8857 4852\nPassword: will be sent the day of the meeting\n\nSlack\n\nFor more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nUsing AlphaFold models to discover distant human and budding yeast homologues\n\n2022-10-14\n\nWe collaborated with the Pfam group at the EBI to evaluate predictions generated from AlphaFold reciprocal best structure hits to identify potential distant orthologs. The Reciprocal Best Structure Hits (RBSH) approach provided 11 novel human homologues, including Pho86 -> NAT8 (ER acetyltransferase), Mug174 -> COIL (Coilin), Ach1 -> OXCT1 (succinyl-CoA:3-ketoacid coenzyme A transferase), SPAC1952.08c -> CREG1, imt1 -> A4GALT (Lactosylceramide 4-alpha-galactosyltransferase), Rtc5 -> MEAK7 (MTOR associated protein). A further 41 novel orthologs were predicted between S. pombe and S. cerevisiae which had fallen under the radar for all other methods used at PomBase. Most of the novel connections provided additional functional information, or supported existing knowledge for poorly characterised proteins. See supporting data tables S4 and S5 for the complete list of predictions included in PomBase. Article.\n\nNext pombeTalks: Wednesday, October 19th\n\n2022-10-13\n\nThe next online pombeTalks will take place on Wednesday, October 19th. These talks are virtual seminars by and for the fission yeast community and friends.\n\n8:00 San Francisco / 11:00 NY / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / midnight Tokyo\n\nTalks this session:\n\n-  Cecilia D’Alessio, University of Buenos Aires and CONICET\n “N-Glycosylation and glycoprotein folding in fission yeasts, a model to study human congenital disorders of glycosylation”\n\n-  Jason Tanny, McGill University, Montreal\n “A novel transcriptional mechanism regulating the cellular response to replication stress”\n\nZoom details\n\nTopic: PombeTalks S03E06 Zoom Meeting\nTime: Oct 19, 2022 05:00 PM Paris\nMeeting ID: 933 7072 6178\nPassword: will be sent the day of the meeting\n\nSlack\n\nFor more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nNew to fission yeast? check out our quick start guide for new users\n\n2022-10-13\n\nWe have added a new page providing useful information for new fission yeast researchers:\nGetting started with S.pombe and PomBase\n\nIncludes details of how to join the community mailing list and the Slack channel, links to useful tools and resources, information about fission yeast as a model organism, an overview of PomBase and more.\n\n77 new disease gene associations\n\n2022-09-16\n\nWe have added 77 new disease-gene associations for 71 fission yeast human gene orthologs. These were identified using “PombeMine” to identify the disease genes curated by OMIM not annotated with an existing MONDO mapping. The number of human disease gene associations is currently 1471. Disease genes can be browsed via the disease slim set or from the MONDO root node term.\n\nPombeMine: an InterMine instance for S. pombe\n\n2022-09-16\n\nAs part of an Elixir funded collaboration with the InterMine team we have created PombeMine. Gene lists can be sent directly from PomBase query results pages directly to Intermine (under the “export” tab), providing direct (2 click) access to GO and phenotype enrichment tools.\n\nNext pombeTalks: Wednesday, September 21st\n\n2022-09-15\n\nThe next online pombeTalks will take place on Wednesday, September 21st. These talks are virtual seminars by and for the fission yeast community and friends.\n\n8:00 San Francisco / 11:00 NY / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / midnight Tokyo\n\nTalks this session:\n\n-  Manuel Lera Ramirez, PomBase / Tran Lab, Institute Curie “Microtubule rescue at midzone edges promotes overlap stability and prevents spindle collapse during anaphase B”\n\n-  Hannah Opalko, Moseley lab, Dartmouth College “Mechanisms of spatial patterning of cell cycle regulator Cdr2”\n\nZoom details\n\nTopic: PombeTalks S03E05 Zoom Meeting\nTime: Sep 21, 2022 05:00 PM Paris\nMeeting ID: 985 8572 1420\nPassword: will be sent the day of the meeting\n\nSlack\n\nFor more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nProtein sequence changes\n\n2022-09-06\n\n78 protein have been shortened (at the N-term). This set includes 34 published proteins (Apl4, Brc1, Cdc48, Cdt1, Cho1, Cmb1, Cut2, Cut6, Cwf26, Dbr1, Dri1, Elo2, Eri1, Lsd2, Lys2, Med13, Naa38, Nup107, Nup82, Orc2, Pof10, Ppt1, Rec24, Rga2, Rmt3, Rns1, RRpn7, Sap145, Skb1, Snf5, Snt2, Spn3, Tpp2, Trm1, and Tup12). Allele description changes and modification position changes are pending.\n\nNext pombeTalks: Wednesday, August 17th\n\n2022-08-13\n\nThe next online pombeTalks will take place on Wednesday, August 17th. These talks are virtual seminars by and for the fission yeast community and friends.\n\n8:00 San Francisco / 11:00 NY / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / midnight Tokyo\n\nTalks this session:\n\n-  Pranas Grigaitis, Vrije Universiteit Amsterdam\n “Prediction of metabolic strategies in Schizosaccharomyces pombe based on optimal resource allocation”\n-  Abhishek Poddar, University of Toledo\n “Membrane stretching activates calcium-permeability of a putative channel Pkd2 during fission yeast cytokinesis”\n\nAs always, connection details will be sent the day of the talk. For more fission yeast related topics and recordings of the talks, join pombeSlack, where additional questions can also be posted on the #pombetalks-qna channel.\n\nNext pombeTalks: Wednesday, July 20th\n\n2022-07-12\n\nThe next online pombeTalks will take place on Wednesday, July 20th. These talks are virtual seminars by and for the fission yeast community and friends.\n\n0:00 San Francisco / 3:00 New York / 8:00 London / 9:00 Paris / 12:30 Delhi / 15:00 Beijing / 16:00 Tokyo.\n\nTalks this session:\n\n-  Leeba Ann Chacko, Ananthanarayanan Lab, University of New South Wales\n “Microtubules and mitochondria cooperate to ensure cell division symmetry, polarity and equipartitioning in fission yeast”\n-  Dan Zhang, Temasek Life Sciences Laboratory, National University of Singapore\n “The cortical ER remodeling for actomyosin ring assembly”\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and pombeSlack one day in advance, so make sure you’ve signed up.\n\nPombeTalks Wednesday June 15th\n\n2022-06-14\n\nThe next online pombeTalks will take place on Wednesday June 15th. These are virtual seminars by and for the fission yeast community and friends.\n\n08:00 San Francisco / 11:00 New York / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / 00:00 Tokyo\n\nTalks this session:\n\n-  Elliott Chapman, Bayne Lab, University of Edinburgh\n “Separable roles for RNAi in regulation of transposable elements and viability in the fission yeast Schizosaccharomyces japonicus”\n-  Fei Li, New York University\n “Phosphorylation-mediated Ccp1-Ndc80 switch at the N-terminus of CENP-T regulates kinetochore assembly in fission yeast”\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and pombeSlack one day in advance, so make sure you’ve signed up.\n\nAs before, questions will be posted to #pombetalks-qna on pombeSlack channel and recordings uploaded.\n\nPombeTalks May 18th\n\n2022-05-05\n\nThe next online pombeTalks will take place on May 18th. These are virtual seminars by and for the fission yeast community and friends.\n\n08:00 San Francisco / 11:00 New York / 16:00 London / 17:00 Paris / 20:30 Delhi / 23:00 Beijing / 00:00 Tokyo\n\nTalks this session:\n\n-  Jennifer Porat, Bayfield Lab, York University: The methyl phosphate capping enzyme Bmc1/Bin3 is a stable component of the fission yeast telomerase holoenzyme\n-  Ingrid Billault-Chaumartin, Martin Lab, UNIL: Fus1, the fusion focus formin\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nNew phenotype slim\n\n2022-04-13\n\nWe have added a phenotype slim overview to complement those provided for disease association, biological process, molecular function and cellular component annotation. The purpose of the phenotype slim is to provide subsets of commonly used ‘broad’ phenotypic classes or annotation subsets that can provide a useful starting point for accessing phenotype lists. The phenotype slim page provides links to ontology term pages, annotated genes, and to download files containing the slim terms and IDs.\n\nThe phenotype slim has also been added to the PomBase advanced search results panel “Slim with” menu. For example, you can query for all genes involved in a GO process, another phenotype, or any other list, and “slim” the results using the “Phenotype slim” option to view categories of phenotypes assigned to the list.\n\nMaking biological knowledge useful for humans and machines\n\n2022-04-04\n\nA GENETICS special issue featuring model organism database updates is published today. This issue features the recent PomBase and JaponicusDB publications and is accompanied by an editorial “Making biological knowledge useful for humans and machines” co-authored by Val Wood, Paul Sternberg and Howard Lipshitz.\n\n-  Fission stories: using PomBase to understand Schizosaccharomyces pombe biology\n-  JaponicusDB: rapid deployment of a model organism database for an emerging model species\n\nThe fission yeast community have now curated over 1000 publications\n\n2022-03-26\n\nWe would like to extend a huge “thank you” to the fission yeast community for curation contributions. The community have now curated 1008 publications providing 19,156 independent annotations, representing 25% of the curation from small-scale publications. In addition, another 80,000 annotations have been provided via the submission of HTP datasets.\n\nPlease contact us via the helpdesk if you would like to provide curation for your manuscript but don’t know how.\n\nLinks:\n\n-  All community curated publications\n-  Spotlights\n-  Canto curation tool\n-  HTP data and browser track submission\n\nNew human orthologs including 3 MRP complex subunits\n\n2022-03-23\n\nWe continue to identify distant human orthologs. Four new 1:1 human ortholog connections have been added to PomBase this week:\n\n-  RNase MRP subunit Rmp1 = human NEPRO (family submitted to Pfam)\n-  RNase P and RNase MRP subunit Pop23 = human RPP38 (members of the same Pfam clan)\n-  RNase P and RNase MRP subunit Pop8 = human RPP14 (family submitted to Pfam)\n-  glutamyl-tRNA amidotransferase complex subunit 3 (Gtf1) = human GATC\n\nHuman NEPRO is a poorly characterised protein linked to the disease Anauxetic dysplasia 3, and GATC is the causal gene for “combined oxidative phosphorylation deficiency 42”\n\nPomBase now uses InterPro Version 88.0\n\n2022-03-12\n\nPomBase now uses InterPro Version 88.0.\n\nFeatures include:\n\n-  The addition of 39 InterPro entries (40,071 total entries)\n-  Integration of 45 new methods from the PRINTS (1), SMART (1), Pfam (2), SUPERFAMILY (7), CATH-Gene3D (14), PANTHER (13), CDD (7) databases\n\nTOR and nutritional phosphoproteome dataset loaded\n\n2022-03-11\n\nWe have loaded the TOR and nutritional phosphoproteome dataset described in Halova et al. (9424 annotations). Many thanks to Janni Petersen for preparing the files.\n\nPublication page for PMID:33823663\n\nAn additional 5775 novel curated lncRNAs from Atkinson et al.\n\n2022-03-10\n\nWe have added an additional 5775 novel curated lncRNAs from Atkinson et al. to PomBase. We will refine the descriptions of these gene products to align with Sequence Ontology (SO) terms describing RNA features in the coming months.\n\nThanks to María Rodríguez-López for preparing the files.\n\nPublication page for PMID:29914874\n\nPomBase & JaponicusDB publications in the GENETICS MOD reports special issue\n\n2022-02-02\n\nPapers describing PomBase and JaponicusDB are now published (early online). These articles are part of a special issue of GENETICS devoted to model organism database (MOD) reports. The MOD papers will highlight the journal’s new section on Computational Resources, Software & Databases.\n\n-  Fission stories: using PomBase to understand Schizosaccharomyces pombe biology\n-  JaponicusDB: rapid deployment of a model organism database for an emerging model species\n\nImproved options for filtering annotations by cell cycle phase\n\n2021-12-19\n\nThe Gene Ontology annotation filter for “during” specific cell cycle phases is now included on the “Summary” view in addition to the “Details” view. Available phases have been extended to cover all phases used, and to provide\nuseful grouping terms. This filter is “ontology aware” (i.e. a search on interphase will also display G1/S/G2 phase annotation). The phase filter is most useful on pages that display increasing volume of phase-specific curation (such as cdc2). The revised phase filter options are also available in the gene expression section.\n\nThe phase filters are located at the top right of GO and gene expression annotation sections:\n\n[During filter]\n\nPomBase now uses InterPro Version 87.0\n\n2021-11-23\n\nPomBase now uses InterPro Version 87.0, which integrates:\n\n-  1,155 new InterPro entries\n-  Update to Pfam 34.0\n-  1,256 new methods\n\nCoils, disorder, and more: new protein feature queries\n\n2021-10-18\n\nThe PomBase advanced search now allows you to find proteins that have coiled-coil regions, disordered regions, and low-complexity regions. The query-building interface also now organises query options more sensibly, and the documentation has been updated.\n\nPomBase & JaponicusDB preprints\n\n2021-09-27\n\nPapers describing PomBase and JaponicusDB will appear in an issue of GENETICS devoted to model organism database (MOD) reports. The MOD papers will highlight the journal’s new section on Computational Resources, Software & Databases.\n\nFollow the links to the PomBase preprint and JaponicusDB preprint, and watch for the full-fledged publications to appear in March 2022.\n\nJaponicusDB: a new fission yeast database\n\n2021-09-01\n\nWe are delighted to announce the official release of PomBase’s new sister: JaponicusDB is a new, curated model organism database for the fission yeast Schizosaccharomyces japonicus. JaponicusDB highlights include revised gene structures, distant ortholog detection, improved GO annotation, community literature curation, and reciprocal gene page links with PomBase, providing a familiar environment for all fission yeast researchers.\n\nThe S. japonicus community will maintain JaponicusDB from now on. Join the new mailing list, and follow @japonicusdb on Twitter.\n\nImproved gene-disease curation: over 1400 S. pombe genes\n\n2021-08-06\n\nPomBase disease gene curation associates disease descriptors with fission yeast orthologs of human disease-causing genes. We have added new gene–disease term connections, to bring the total to 1401 S. pombe genes. Disease associations now cover 27.3% of all fission yeast protein-coding genes, and almost 40% with human orthologs.\n\nPombeTalks August 4th\n\n2021-07-28\n\nThe next online PombeTalks will take place on Wednesday 4th August 2021, at 17:00 Central European Time. Speakers:\n\n-  Tiffany Mak, Nurse lab, The Francis Crick Institute: The TOR-dependant phosphoproteome and regulation of cellular protein synthesis\n\n-  Weifang Wu, Allshire lab, University of Edinburgh: Spatial organisation of the nucleus influences centromere identity\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nAfter these talks, PombeTalks will take a break for the rest of the summer, so watch this space, pombelist, or PombeSlack for updates. In the meantime, you can fill out this form at any time if you’re interested in speaking.\n\nAlphaFold links\n\n2021-07-28\n\nPomBase gene pages now have links to the AlphaFold Protein Structure Database, the collection of structures predicted by AI developed by DeepMind, hosted at EBI. Look in the “External references” section of your favorite gene page, or check out this example (pap1), or read more at the EBI AlphaFold home.\n\nPombeTalks July 21st\n\n2021-07-14\n\nThe next online PombeTalks will take place on Wednesday 21st July 2021, at 10:00 Central European Time / 17:00 Japan & Korea. Speakers:\n\n-  Yoko Otsubo, Yamashita lab, National Institute for Basic Biology: Novel links between TORC1 and traditional non-coding RNA, tRNA\n\n-  Jie Su, Nakagawa lab, Osaka University: Rad8-dependent PCNA ubiquitination at lysine 107 causes gross chromosomal rearrangements\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nKEGG pathway links\n\n2021-07-06\n\nPomBase gene pages now have links to pathway entries in the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, as well as links to gene lists for each linked pathway (example: 2-Oxocarboxylic acid metabolism). The KEGG pathway links are the first entry in a new gene page section, “Molecular pathway”, dedicated to connecting genes in PomBase to depictions of biochemical and signaling pathways.\n\nPomBase now uses InterPro Version 86.0\n\n2021-06-30\n\nPomBase now uses InterPro Version 86.0, which integrates:\n\n-  299 new InterPro entries\n-  An update to PROSITE patterns [2021_01] and PROSITE profiles [2021_01]\n-  454 new methods from the PROSITE profiles (39), SMART (2), Pfam (7), SUPERFAMILY (3), CATH-Gene3D (80), PANTHER (295), CDD (27), SFLD (1) databases.\n\nInterPro cites 52235 publications in PubMed. See the InterPro release notes for further information.\n\nPombeTalks July 7th\n\n2021-06-30\n\nThe next online PombeTalks will take place on Wednesday 7th July 2021, at 17:00 Central European Time. Speakers:\n\n-  Debatrayee Sinha, Qian Chen lab, University of Toledo: Fission yeast polycystin Pkd2p promotes resumption of cell growth after cytokinesis\n\n-  Joël Lemière, Fred Chang Lab, UCSF: The role of osmotic forces in nuclear size control\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks June 23rd\n\n2021-06-17\n\nThe next online PombeTalks will take place on Wednesday 23rd June 2021, at 17:00 Central European Time. Speakers:\n\n-  Yi Wei, Grewal lab, NCI CCR, Bethesda: TOR targets an RNA processing network to regulate cell proliferation and sexual development\n\n-  Nicholas Ader, LusKing Lab, Yale School of Medicine: I open at the close(d mitosis): Investigating post-mitotic nuclear envelope sealing in fission yeast\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nViolin plots for gene expression\n\n2021-06-15\n\nThe “Quantitative gene expression” section of PomBase gene pages now offers a display of violin plots to visualize where the gene appears in available expression datasets.\n\nViolin plots are also available to visualize sets of up to 150 genes in the advanced search results.\n\nAt present data from Marguerat S et al. (2012) and Carpy A et al. (2014) are included.\n\nPombeTalks June 9th\n\n2021-06-02\n\nThe next online PombeTalks will take place on Wednesday 9th June 2021, at 10:00 Central European Time / 17:00 Japan & Korea. Speakers:\n\n-  Yusuke Toyoda, Saitoh lab, Kurume University: Nitrogen-dependent persistence of S. pombe Ght5 glucose transporter on the cell surface is effected by TORC2 inhibition of α-arrestin Aly3\n\n-  Anupa T. Anil, Mishra lab, IISER Mohali: How does spliceosome capture branchpoint-distant 3’ splice site?\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks May 26th\n\n2021-05-20\n\nThe next online PombeTalks will take place on Wednesday 26th May 2021, at 17:00 Central European Time. Speakers:\n\n-  Mélina Vaurs (Vincent Géli & Stéphane Coulon labs - Cancer Research Center, Marseille): Shelterin-dependent telomerase regulation differs between quiescent and vegetative cells\n\n-  Arthur Molines (Fred Chang lab – UCSF): Physical properties of the cytoplasm modulate microtubule dynamics\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks May 12th\n\n2021-05-05\n\nThe next online PombeTalks will take place on Wednesday 12th May 2021, at 17:00 Central European Time. Speakers:\n\n-  Sierra Cullati, Gould lab, Vanderbilt University: Autophosphorylation of the CK1 Kinase Domain Regulates Enzyme Activity and Substrate Specificity\n\n-  Stephen Huisman, Brunner Lab, University of Zurich: Vip1, a temperature-dependent filament forming protein involved in cell length regulation\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nNew diploid genotype & phenotype display\n\n2021-04-29\n\nPomBase now includes pages for curated diploid genotypes, and displays phenotypes annotated to them on gene and publication pages. For more details see the documentation for phenotype annotations and genotype pages.\n\nPombeTalks April 28th\n\n2021-04-22\n\nThe next online PombeTalks will take place on Wednesday 28th April 2021, at 10:00 Central European Time / 17:00 Japan & Korea. Speakers:\n\n-  Tomoyuki Fukuda, Niigata University Graduate School of Medical and Dental Sciences: Atg43 serves as a selective autophagy receptor to promote mitophagy\n\n-  Xiao-Ran Zhang, NIBS, Beijing, China: An improved auxin-inducible degron system for fission yeast\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPomBase now uses InterPro Version 85.0\n\n2021-04-15\n\nPomBase now uses InterPro Version 85.0, which integrates:\n\n-  157 new InterPro entries\n-  An update to CATH-Gene3D [4.3.0]\n-  333 new methods from the Pfam (3), SUPERFAMILY (11), CATH-Gene3D (168), PANTHER (88), CDD (62), SFLD (1) databases\n\nInterPro cites 51539 publications in PubMed. See the InterPro release notes for further information.\n\nPombeTalks April 14th\n\n2021-04-08\n\nThe next online PombeTalks will take place on Wednesday 14th April 2021, at 17:00 Central European Time:\n\n-  Pabitra Parua,�Fisher�lab,�Icahn School of Medicine at Mount Sinai: Control of the RNA polymerase II transcription cycle by CDK-phosphatase switches\n\n-  Ye Dee Tay, Sawin Lab,�University of�Edinburgh: Gef1: the first aider of Cdc42 polarity module during stress\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the new Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nNew genome browser data: GC content\n\n2021-03-31\n\nA data track showing the fraction of G/C bases in a region is now available in PomBase JBrowse, listed under “Base composition”. The track is generated using the gccontent plugin, and uses a default window of 100 bp.\n\nQualitative gene expression annotation in Canto\n\n2021-03-31\n\nCanto, PomBase’s online curation tool, now supports qualitative gene expression annotation. Two new annotation types are available to represent observations about the levels of RNA or protein observed in wild-type cells, and how they change over the cell cycle or in response to a stimulus. See the Canto documentation for more information. We have also updated the display of qualitative gene expression on PomBase gene and publication pages.\n\nNew protein feature display\n\n2021-03-30\n\nPomBase has released a new, interactive display for protein features on gene pages. The new view is clearer, with details for each feature available via mouseover as well as in the accompanying table.\n\nIn addition, PomBase now uses InterPro Version 84.0, which includes 205 new entries and integrates 252 new methods from the Pfam, PANTHER, and CDD databases. See the InterPro release notes for further information.\n\nPombeTalks March 31st\n\n2021-03-27\n\nThe next online PombeTalks will take place on Wednesday 31st March 2021, at 17:00 Central European Time:\n\n-  Udo Onwubiko, Das lab, University of Tennessee: Cdc42 prevents early Rho1 activation during cytokinesis\n\n-  Chunmin Shan, Jia lab, Columbia University: The INO80 complex regulates epigenetic inheritance of heterochromatin\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the new Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks March 17th - new time!\n\n2021-03-10\n\nThe new season of online PombeTalks for 2021 will begin on Wednesday 3rd March 2021, at a different time: 9:00 Central European Time / 17:00 Japan & Korea. Speakers:\n\n-  Yasuto Murayama, National Institute of Genetics, Shizuoka: Biochemical analysis of the fission yeast structural maintenance of chromosomes complex\n\n-  Ken Ishikawa, Kurume University, Kurume: dCas9-mediated CRISPRi for S. pombe\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will continue with its fortnightly schedule, and every third session will take place at the new Asia-friendly time. Watch this space, pombelist, or PombeSlack for updates, and please fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks return March 3rd\n\n2021-02-24\n\nThe new season of online PombeTalks for 2021 will begin on Wednesday 3rd March 2021 at 17:00 Central European Time:\n\n-  Maria Rodriguez Lopez, Bähler lab, UCL: Clr6 orchestrates transcriptional switches to regulate metabolism during oxidative stress\n\n-  Olivia Muriel-Lopez, Martin lab, University of Lausanne: ’Ultrastructural plasma membrane asymmetries underlie cell-cell fusion in S. pombe*\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nPombeTalks will resume its fortnightly schedule, so watch this space, pombelist, or PombeSlack for updates. As in the past, you are always welcome to fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPomBase identifier mapper now available\n\n2021-02-04\n\nWe have developed an identifier mapper that retrieves S. pombe gene systematic IDs and standard names for a selection of different input ID types. You can now find S. pombe genes using UniProt accessions, and retrieve manually curated orthologs for S. cerevisiae using standard gene names or ORF names, and for human using standard gene names or HGNC identifiers.\n\nTry the identifier mapper or check out the documentation.\n\nPomBase now uses InterPro Version 83.0\n\n2021-01-25\n\nPomBase now uses InterPro Version 83.0, which integrates:\n\n-  376 new InterPro entries\n-  An update to HAMAP [2020_05], CDD [3.18]\n-  462 new methods from the SMART (2), TIGRFAMs (2), Pfam (3), PANTHER (140), HAMAP (19), CDD (286), SFLD (10) databases\n\nInterPro cites 50487 publications in PubMed. See the InterPro release notes for further information.\n\nFirst S. pombe microPublication goes live\n\n2021-01-07\n\nThe first fission yeast microPublication has now been published:\n\nNafees Ahamad, Simmi Anjum, Shakil Ahmed\\ Pyrogallol induces oxidative stress defects in the fission yeast S. pombe.\n\nCongratulations to the authors, and thanks to the microPublication team!\n\nPombeTalks November 25th\n\n2020-11-18\n\nThe last online PombeTalks for 2020 will take place on Wednesday 25th November 2020 at 17:00 Central European Time:\n\n-  I-Ju Lee, David Pellman’s Lab, Dana-Farber Cancer Institute: Factors promoting nuclear envelope assembly independent of the canonical ESCRT pathway\n\n-  Ulrike Endesfelder, Carnegie Mellon University: TBC\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nAfter these talks, PombeTalks will take a well-earned break, and return in early 2021. The schedule is available, and you are always welcome to fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks November 11th\n\n2020-11-04\n\nThe next online PombeTalks will take place on Wednesday 11th November 2020 at 17:00 Central European Time:\n\n-  Farnaz Mansouri, Mark Bayfield lab (York University, Toronto): The uncharacterized S. pombe La-related protein 1 functions in translation and affects RNA abundance\n\n-  Saz Basu, Paul Nurse lab (Francis Crick Institute, London): Unmasking the mitotic potential of G1/S Cyclin-CDK\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on November 25. PombeTalks will then take a break, and return in early 2021. The schedule is available, and you are always welcome to fill out this form if you’re interested in speaking.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nGO annotations from PAINT\n\n2020-11-01\n\nPomBase now includes over 3000 GO annotations made using Phylogenetic Annotation and INference Tool (PAINT), developed by the GO Consortium to infer protein function in a phylogenetic context, supporting precise assertions as to when functions were gained and lost during evolution. PAINT annotations use the evidence code “inferred from biological aspect of ancestor” (IBA). PAINT curation is described in more detail in Gaudet et al. 2011.\n\nPombeTalks October 28th\n\n2020-10-24\n\nThe next online PombeTalks will take place on Wednesday 28th October 2020 at 17:00 Central European Time:\n\n-  Omaya Dudin, EPFL, Switzerland: Cellularization of Ichthyosporean coenocytes\n\n-  Bassem Al-Sady, UCSF, USA: Single cell analysis of the heterochromatin spreading reaction\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on November 11, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks October 14th\n\n2020-10-08\n\nThe next online PombeTalks will take place on Wednesday 14th October 2020 at 17:00 Central European Time:\n\n-  Dimitrios Vavylonis, Lehigh University: Modeling fission yeast’s polarization pattern\n\n-  Chloe Snider, Gould Lab, Vanderbilt University: Opposite surfaces of the Cdc15 F-BAR domain create a membrane platform that coordinates cytoskeletal and signaling components for cytokinesis\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on October 28, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks September 30th\n\n2020-09-23\n\nThe next online PombeTalks will take place on Wednesday 16th September 2020 at 17:00 Central European Time:\n\n-  Alexander Lorenz, University of Aberdeen, UK: Meiotic recombination outcome in the face of genetic diversity\n\n-  Veneta Gerganova, Martin Lab, UNIL, Switzerland: Patterning of membrane-associated proteins through membrane flows\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on October 14, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nNew genome browser datasets 2020-09-17\n\n2020-09-17\n\nTwo new datasets in are now available in PomBase JBrowse (links go to PomBase publication pages, which in turn link to the browser with the tracks enabled):\n\n-  Meiotic DSBs from\n Fowler KR, Gutiérrez-Velasco S, Martín-Castellanos C, Smith GR. 2013.\n Protein determinants of meiotic DNA break hot spots.\n PMID:25747261 DOI: 10.1016/j.molcel.2013.01.008\n\nand\n\n-  Time-lapse single-cell transcripts for dormancy breaking from\n Tsuyuzaki H, Hosokawa M, Arikawa K, Yoda T, Okada N, Takeyama H, Sato. 2020.\n Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast.\n PMID:32152323 DOI: 10.1016/j.molcel.2013.01.008\n\nMore datasets are always welcome, so check out our instructions for submission.\n\nPombeTalks September 16th\n\n2020-09-14\n\nThe next online PombeTalks will take place on Wednesday 16th September 2020 at 17:00 Central European Time:\n\n-  Susan Forsburg, University of Southern California: Visualizing replication stress\n\n-  Sigurd Braun, Ludwig-Maximilians-Universität, München: Gene repression at the nuclear membrane: Multifaceted roles of Lem2\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on September 30, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nNew dataset: Hermes transposon insertions\n\n2020-09-11\n\nPomBase now hosts transposon integration data from Lee et al. 2020. Henry Levin explains the background and significance of the work:\n\n“Transposon Integration Sequencing is a genome wide method of mapping sequences that contribute to growth. High throughput sequencing of transposon integration sites in haploid cells with single insertions reveals which genes are dispensable. Once propagated, cultures exhibit a pronounced lack of insertions in genes necessary for growth. This method, originally developed to study bacteria is now used to characterize the genomes of several yeasts including S. pombe. In earlier work we used the transposon Hermes to identify genes of S. pombe required for growth (Guo et al., 2013, Genetics, PMID:23893486). We have now applied Hermes and Transposon Integration Sequencing to identify genes important for the formation of heterochromatin (Lee et al., 2020, Cell Reports, PMID:32101745). Insertion sites from eight independent cultures can be visualized from PomBase as custom tracks on Jbrowse. Four cultures were of cells with ura4 silenced by cen1 heterochromatin. The other four cultures were\nof a strain without ura4. By passaging the cultures in 5-FOA we selected against cells with defects in heterochromatin. Genes that contributed to the formation of heterochromatin exhibited fewer insertions in cells with the cen1 copy of ura4 relative to the strain lacking ura4. To distinguish genes critical for heterochromatin from genes that contribute to a lesser extent we passaged cultures in 5-FOA for 5 generations and for 80 generations. While viewing these integration sites can indicate whether genes of interest contribute to heterochromatin formation you can also examine insertions in the cultures lacking ura4 to gage whether specific genes or noncoding sequences make significant contributions to growth.”\n\nNew genome browser datasets 2020-09-08\n\n2020-09-08\n\nThree new datasets in are now available in PomBase JBrowse (links go to PomBase publication pages, which in turn link to the browser with the tracks enabled):\n\n-  Transcription start sites from\n Li H, Hou J, Bai L, Hu C, Tong P, Kang Y, Zhao X, Shao Z. 2015.\n Genome-wide analysis of core promoter structures in Schizosaccharomyces pombe with DeepCAGE.\n PMID:25747261 DOI:10.1080/15476286.2015.1022704\n\n-  Transcript data from\n Eser P, Wachutka L, Maier KC, Demel C, Boroni M, Iyer S, Cramer P, Gagneur J. 2016\n Determinants of RNA metabolism in the Schizosaccharomyces pombe genome.\n PMID:26883383 DOI:10.15252/msb.20156526\n\n-  Transposon insertion sites from\n Lee SY, Hung S, Esnault C, Pathak R, Johnson KR, Bankole O, Yamashita A, Zhang H Levin HL.\n Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation.\n PMID:32101745 DOI:10.1016/j.celrep.2020.01.094\n\nSubmit your genome browser data\n\n2020-09-08\n\nWe have updated our HTP data submission procedure to make it easier for you to contribute your datasets for PomBase JBrowse:\n\nWe now provide spreadsheet templates in Excel and Open Document formats that gather the metadata we need to load and display your data. You can download a template from the documentation page on HTP data submission. Send completed spreadsheets to the PomBase helpdesk.\n\nPublished: GO Term Matrix for annotation QC\n\n2020-09-02\n\nIn collaboration with the GO Consortium, the PomBase team has published a report on the Term Matrix approach to GO annotation quality control. The article, out this week in Open Biology, describes biological processes that do, or don’t, share annotated gene products, and how we use co-annotation patterns to build rules to detect, correct, and prevent errors.\n\nPombeTalks September 2nd\n\n2020-09-01\n\nThe next online PombeTalks will take place on Wednesday 2nd September 2020 at 17:00 Central European Time:\n\n-  François Bachand, USherbrooke, Canada: Proximity-dependent biotinylation assays in fission yeast and a tale about slow RNA polymerase II transcription\n\n-  Scott Curran, Nurse Lab, The Crick Institute, UK: A quantitative and spatial analysis of the cell cycle control network\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on September 16, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\n11th Pombe meeting postponed to 2022\n\n2020-08-19\n\nDue to the ongoing Covid-19 pandemic, the 11th International Fission Yeast Meeting, due to take place in Hiroshima, Japan, has been postponed.\n\nThe new dates will be 12th (Sun -17th (Fri) June, 2022.\n\nPlease see the conference website and pombelist for further announcements.\n\nPombeTalks August 19th\n\n2020-08-12\n\nThe next online PombeTalks will take place on Wednesday 19th August 2020 at 17:00 Central European Time:\n\n-  Joe Magliozzi, Moseley Lab, Dartmouth: Cell polarity kinases regulate RNA-binding protein Sts5 to control cell shape\n\n-  Ramakanth Neeli, Minc Lab, Institute Jacques Monod: Mechanisms and Functions of Cell Wall Mechanosensing in Fission Yeast\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on September 2, and the schedule is available for the next few weeks. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks August 5th\n\n2020-07-31\n\nThe next online PombeTalks will take place on Wednesday 5th August 2020 at 17:00 Central European Time:\n\n-  Feng Li, Levin Lab NICHD/NIH, USA: Identification of an integrase-independent pathway of retrotransposition\n\n-  Ivan Surovtsev, King lab, Yale University, USA: Liquid-liquid phase separation, heterochromatin domains and nuclear mechanics\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on August 19, and the summer schedule is available. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nFission yeast microPublications\n\n2020-07-22\n\nPomBase has recently joined microPublication.org, which “publishes brief, novel findings, negative and/or reproduced results, and results which may lack a broader scientific narrative”, as a Partner Database. Fission yeast researchers can thus now make any results available to the community, even those that don’t fit neatly into traditional publications.\n\nVisit the microPublications website to learn more, to register and submit your data, or sign up to review. Send questions to the PomBase helpdesk.\n\nPombeTalks July 22nd\n\n2020-07-21\n\nThe next online PombeTalks will take place on Wednesday 22nd July 2020 at 17:00 Central European Time:\n\n-  Prof. Dr. Ann Ehrenhofer-Murray, Institut für Biologie, Humboldt-Universität zu Berlin: Queuosine and m5c modification of RNA: Nutritional control of translation in S. pombe homestasis\n\n-  Dr. Sarah Sabatinos, Department of Chemistry and Biology, Ryerson University: Long-term effects of surviving replication instability\n\n-  PomBase microPublications announcement (Midori Harris)\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on August 5, and the summer schedule is available. If you’re interested in speaking, please fill out this form.\n\nThanks to the PombeTalks team for organizing. See you online!\n\nPombeTalks July 8th\n\n2020-07-02\n\nThe next online PombeTalks will take place on Wednesday 8th July 2020 at 17:00 Central European Time:\n\n-  Sahana Holla, Grewal lab, NIH: Positioning heterochromatin at the nuclear periphery promotes epigenetic inheritance\n\n-  Nick Rhind, UMass Medical School: Cell size is controlled by size-dependent expression of mitotic activators\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also see PombeSlack for Q&A after the talks, and for recordings of previous sessions.\n\nThe next talks are on July 22nd, and the summer schedule is available. If you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nPombeTalks June 24th\n\n2020-06-19\n\nThe next online PombeTalks will take place on Wednesday 24th June 2020 at 17:00 Central European Time:\n\n-  Sito Torres-Garcia, Allshire lab, University of Edinburgh: Epigenetic gene silencing by heterochromatin primes fungal resistance\n\n-  Julie Rich-Robinson, Das lab, University of Tennessee: Cell-cycle-dependent cues temporally regulate Cdc42 activity at growth sites in fission yeast\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up.\n\nA schedule is now available for the rest of the summer, including the next talks on July 8th. If you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nEditable PomBase query names\n\n2020-06-11\n\nEntries in the PomBase advanced search query history now show brief, user-editable query descriptions, and a toggle to show or hide additional details.\n\nPombeTalks POSTPONED to June 17th\n\n2020-06-05\n\nPlease note that the next online PombeTalks will take place one week later than originally planned, to support the STEM Strike for Black Lives on 10th June.\n\nIn the meantime, please complete this brief survey of the audience.\n\nOn Wednesday 17th June 2020 at 17:00 Central European Time, the speakers will be:\n\n-  Gautam Dey, Baum lab, UCL / EMBL Heidelberg: Closed mitosis requires local disassembly of the nuclear envelope\n\n-  Meredith Betterton, UC Boulder: Computational modeling of fission yeast mitosis: what we can learn about pombe from computer simulations\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. The next two sessions will b on June 27 and July 8. If you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nPombeTalks May 27th\n\n2020-05-21\n\nThe next online PombeTalks will take place on Wednesday 27 May 2020 at 17:00 Central European Time. This time, in addition to the usual pair of research talks, our own Val Wood will show a few of PomBase’s lesser-known features.\n\n-  Angad Garg, Stewart Schuman’s lab, Memorial Sloan Kettering Cancer Center: Long non-coding RNA control of phosphate homeostasis\n\n-  José López Hernández, Sarah Zander’s lab, Stowers Institute for Medical Research: Diverse mating strategies in S. pombe affect the spread of wtf meiotic drivers\n\n-  Val Wood, PomBase: Hidden corners of PomBase: Ten features you might not have seen\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also mark your calendars for the next two sessions on and June 10 and 24, and if you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nNew fission yeast GO slims\n\n2020-05-20\n\nTo complement the overview provided by the fission yeast GO biological process slim, we have created GO slims for the molecular function and cellular component branches of GO. Each slim page provides links to ontology term pages, annotated genes, and to download files containing the slim terms and IDs.\n\nNew ontology slimming options for advanced search results\n\n2020-05-20\n\nThe PomBase advanced search results panel now allows you to retrieve annotations to any of the fission yeast GO slims or the Mondo disease slim for genes in the results list. For example, you can query for all genes involved in a process and slim the resulting list by molecular function or disease association.\n\nPomBase adopts MONDO for disease gene curation\n\n2020-05-18\n\nPomBase has switched from the Disease Ontology (DO) to the Monarch Initiative’s Mondo Disease Ontology (Mondo) for disease gene curation. Mondo covers the same set of disease descriptions as DO, but has a richer hierarchical structure that classifies more specific descriptions into broad categories (e.g. anemia, cancer, kidney disease) suitable for a disease “slim” term set.\n\nPomBase curators are collaborating with Mondo to improve its disease classification, especially in areas that will support inferences that improve fission yeast disease annotation coverage in the new PomBase Mondo slim. The new disease slim is a work in progress, so if there is a particular disease grouping that you would find useful, please let us know.\n\nImproved gene-disease curation\n\n2020-05-18\n\nPomBase disease gene curation associates disease descriptors with fission yeast orthologs of human disease-causing genes. We have now increased coverage by adding new gene–disease term connections, with 3954 individual annotations to 1195 genes (up from 2588 and 905 respectively in January 2019). Disease associations now cover 24.5% of all fission yeast protein-coding genes, and over one third of those with human orthologs.\n\nPublished: Community curation in PomBase\n\n2020-05-11\n\nThe PomBase team has published an overview of our experience with community curation for fission yeast. In the article, out this week in Database, we reflect on the factors that have made our community’s remarkable, standard-setting achievements possible, and on the benefits we and PomBase users derive from this effort. We highlight the collaboration between authors and professional curators that arises via community curation, and how annotation quality improves as a result.\n\nWatch for invitations to curate your new papers, or see our community curation page for more information.\n\nPombeTalks May 13th\n\n2020-05-07\n\nThe next online PombeTalks will take place on Wednesday 13 May 2020 at 17:00 Central European Time. Speakers:\n\n-  Sarah Lambert, Institut Curie, Paris, France: Resolution of replication stress in space and time for maintaining genome stability\n\n-  Cornelia Kilchert, Justus-Liebig-University, Giessen, Germany: RNA-binding proteins in fission yeast - a global perspective\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also mark your calendars for the next two sessions on May 27 and June 10, and if you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nChromatin silencing ontology & annotation overhaul\n\n2020-05-07\n\nPomBase curators have collaborated with the GO Consortium to improve the representation of chromatin silencing and the underlying heterochromatin organization processes in the GO biological process ontology and annotations.\n\nNotably, “chromatin silencing” terms have been removed from GO on the grounds that they conflated various heterochromatin assembly, formation, and maintenance pathways with processes that affect chromatin-mediated repression more indirectly (e.g. tethering to the nuclear envelope). Chromatin silencing is a phenotype resulting from the cumulative effects of these processes, and the Fission Yeast Phenotype Ontology (FYPO) accordingly retains a full suite of “chromatin silencing” terms.\n\nAnnotations using the GO chromatin silencing terms were reviewed, and either removed or reannotated based on what could be inferred from the phenotypes, resulting in a substantially revised set of heterochromatin assembly annotations. Further work is required, so please send us any corrections.\n\nPomBase now uses InterPro Version 79.0\n\n2020-05-05\n\nPomBase now uses InterPro Version 79.0, which integrates:\n\n-  128 new InterPro entries\n-  An update to PIRSF [3.10]\n-  151 new methods from the SUPERFAMILY (4), CATH-Gene3D (6), PIRSF (9), PANTHER (106), and CDD (26) databases.\n\nInterPro cites 48466 publications in PubMed. See the InterPro release notes for further information.\n\nMitochondrial genome update\n\n2020-05-01\n\nThe mitochondrial genome sequence in PomBase has been updated to reflect corrections made in Tao et al. (2019) “Intraspecific Diversity of Fission Yeast Mitochondrial Genomes”.\n\nMidori Harris receives 2020 Biocuration Career Award\n\n2020-04-28\n\nMidori Harris, ontology developer and curator at PomBase, has been awarded the 2020 Biocuration Career Award.\n\nCongratulations to Midori and a huge thanks for all that you do for PomBase.\n\nPombeTalks start on April 29th\n\n2020-04-22\n\nThe first in the new series of online PombeTalks will take place on Wednesday 29 April 2020 at 17:00 Central European Time. Speakers:\n\n-  Aleksandar Vjeṧtica, Sophie Martin’s lab, University of Lausanne: Cycling for reproductive fidelity: Coupling the cell cycle and re-fertilisation blocks ensures ploidy maintenance during sexual lifecycle\n\n-  Haitong Hou, Julia Cooper’s lab, NCI & University of Colorado: Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8\n\nTalks will be streamed live via Zoom. The link will be circulated via pombelist and PombeSlack one day in advance, so make sure you’ve signed up. Also mark your calendars for the next two sessions on May 13 and May 27, and if you’re interested in speaking, please fill out this form.\n\nThanks to Gautam Dey and the rest of the PombeTalks team for organizing. See you online!\n\nAnGeLi update\n\n2020-03-23\n\nAnGeLi (developed by Danny Bitton) is a tool that allows you to perform enrichments over gene lists.\n\nAnGeLi has recently been updated to provide 9320 lists, including ontology-based annotations from PomBase (as of 2020-03-04) as well as many additional datasets from the Bähler laboratory.\n\nNew search result download options\n\n2020-03-23\n\nThe PomBase Advanced search has added new options to the data you can download for your query results:\n\n-  All physical interactors of a gene product\n-  Deletion viability\n-  Protein length\n\nPomBase now uses InterPro Version 77.0\n\n2020-03-01\n\nPomBase now uses InterPro Version 77.0, which integrates 145 new methods from the CATH-Gene3D (134), and SUPERFAMILY (11) databases. InterPro cites 59894 publications in PubMed. See the InterPro release notes for further information.\n\nCommunity curation response rate reaches 50%\n\n2020-02-28\n\n789/1587 publications assigned to community members for curation are finished. A big thank you to everyone who has participated so far. For more details, and all our curation metrics, see https://curation.pombase.org/pombe/stats/annotation\n\nA quarter of a million annotations\n\n2020-02-20\n\nPomBase recently reached 250,000 annotations to controlled vocabularies and ontologies. The majority (over 90%) are assigned manually from fission yeast experimental data derived from 3776 publications, most of which report low-throughput, hypothesis-driven experiments.\n\nYou can query and combine any of these data types in the Advanced search.\n\nThank you to everyone who contributed to this significant achievement through community curation.\n\nQuery phenotypes for conditions\n\n2020-02-05\n\nThe PomBase advanced search Advanced search now supports using experimental conditions as search criteria for phenotype annotations. For example, you can now query for genes that show abnormal chromosome segregation mutant phenotypes specifically at high or low temperatures. The search uses the same condition descriptors as Canto and the PomBase web pages.\n\nNote that phenotype queries that have condition constraints can be combined, but pay careful attention to the annotations for the results. Future work will add support for querying for multiple conditions on the same annotation, and for specifying conditions to exclude from results.\n\nLevures, Modèles et Outils 14th International Conference\n\n2020-02-04\n\nThe 14th edition of the “Levures, Modèles et Outils” meeting (LMO14) will be held in July 9-11, 2020, at the University of Strasbourg in France. Registration is open February 3rd to June 30th, and abstracts can be submitted from February 3rd to April 10th. Authors will be notified in early May and the final program will be available in early June.\n\nThe sessions will be diverse and present the latest findings using yeast as a model organism on the following topics:\n\n1.  Cell biology, cell cycle, cytoskeleton\n2.  Gene expression regulation\n3.  Population, functional and evolutionary genomics\n4.  Replication, repair and recombination\n5.  Transport, sensing and signaling\n6.  Pathogenic yeast and filamentous fungi\n7.  Tools, resources and databases\n8.  New technologies, yeast and industry\n\nPomBase is now an ELIXIR Node Service\n\n2020-01-17\n\nPomBase has been awarded Node Service status by the UK node of ELIXIR. ELIXIR-UK Node Services support the bioinformatics and broader biological research communities by providing training and resources that help researchers to find and share data, exchange expertise, and agree on best practices at national, European and international levels. The review panel describes PomBase as a “mature, leading model organism database which is popular, unique, well used, and has a strong user community.”\n\nNew vectors for simple, reliable S. pombe molecular biology\n\n2020-01-07\n\nTo enable fission yeast researchers to manipulate S. pombe molecular biology reproducibly and easily, Aleks Vještica and Magdalena Marek in Sophie Martin’s lab have designed and constructed a series of simple, fully characterized plasmids.\n\nThe Stable Integration Vector (SIV) series provides a highly modular toolbox to introduce heterologous sequences more stably was possible with than previously available vectors. The toolkit includes antibiotic resistance markers, promoters, fluorescent tags, and terminators, as well as large set of ready-to-use fluorescent probes to mark organelles and visualize cellular processes.\n\nThe work is published in the Journal of Cell Science, and a PomBase publication page is available.\n\nUnique permanent URLs for search results\n\n2019-11-28\n\nAll result pages from the Advanced search now have a unique permanent URL that can be bookmarked and shared with your colleagues.\n\nThe QuiLT and GO slim pages also now have permanent URLs.\n\nBrowser tracks now loadable from publication pages\n\n2019-10-16\n\nData tracks from datasets hosted in the PomBase genome browser can now be browsed and loaded from their respective publication pages. For an example, see Atkinson et al. (2018). Data tracks are now also downloadable from the publication pages.\n\nNew PomBase funding from the Wellcome Trust\n\n2019-10-07\n\nWe are pleased to announce that the recent PomBase application for continued Wellcome Trust funding was successful. Although the grant was not fully funded, we are confident that we can cover the shortfall by small grants for stand-alone projects and collaborations. We would like to thank the pombe community for their support with the application, and the Wellcome Trust for their continued funding. We look forward to supporting your research until 2025 (and beyond).\n\nPomBase now uses InterPro Version 76.0\n\n2019-10-06\n\nPomBase now uses InterPro Version 76.0, which integrates 277 new methods from the CATH-Gene3D (1), PANTHER (178) and CDD (98) databases. InterPro cites 59846 publications in PubMed. See the InterPro release notes for further information.\n\nReplication origin data loaded into JBrowse\n\n2019-08-30\n\nWe have loaded data from: Segurado et al. (2003) “A+T-rich islands”, Hayashi et al. (2007) “Pre-replicative complex localization; early and late firing origins”, and Mickle et al. (2007) “Replication origins with functional classification”.\n\nTo view the tracks, either follow the hyperlinks above to the respective PomBase publication pages, and click on the “view” link after “Datasets from this publication are available in the PomBase JBrowse genome browser”, or go directly to the browser and click on the “select tracks” button to find the tracks manually.\n\nFor anyone new to JBrowse we have a quick start guide.\n\nJoin the conversations on Slack\n\n2019-07-19\n\nThe vibrant fission yeast community now has a Slack channel. Slack provides a forum for the research community. Follow conversations you care about, message colleagues privately, or in groups, ask questions, post responses. All archived and searchable.\n\n-  See the PombeSlack flyer for more information, including how to join.\n\n“Fitness Landscape of the Fission Yeast Genome” dataset loaded into JBrowse\n\n2019-07-11\n\nWe have loaded the Grech et al. (2019) “Fitness Landscape of the Fission Yeast Genome” dataset into JBrowse. In this study, transposon mutagenesis libraries were created to map transposon insertion sites in the S. pombe genome. From this data, functional elements of the genome were inferred. The tracks from this study can be loaded by a single click from the linked publication page above\n\nThanks Dan Jeffares for sending us the data.\n\nFor anyone new to JBrowse we have a quick start guide.\n\ntRNA metabolism GO annotation update\n\n2019-05-19\n\nThe process of tRNA metabolism, and the associated molecular functions have recently been reviewed.\n\n-  “tRNA metabolic process” annotation\n-  genes for “tRNA metabolic process”\n\nPlease let us know if the annotation can be further improved.\n\nCustomisable FASTA download\n\n2019-04-18\n\nYou can now download nucleotide or peptide sequences for genes in Advanced search results in FASTA format, and customise what is included in the FASTA headers (e.g. gene names, product descriptions, sequence coordinates, or various IDs can be included).\n\nNew homology modelling and ortholog links on gene pages\n\n2019-04-18\n\nWe have added new external links to PomBase gene pages for structure and ortholog predictions:\n\n-  Protein-specific links to SWISS-MODEL, a fully automated protein structure homology-modelling server, accessible via the ExPASy web server, lead to a SWISS-MODEL Repository page for each sequence and present results. If no structure or model is available, you can either trigger adding an entry to the repository with a single click or easily interactively search for templates and build models in your own SWISS-MODEL workspace.\n\n-  Ensembl Fungi Compara and Ensembl Pan-taxonomic Compara links lead to orthology predictions from the Ensembl Compara pipeline for fungi and all species, respectively.\n\n-  PANTHER links retrieve gene information, classification, and predicted orthologs.\n\nPomBase InterPro Update\n\n2019-04-17\n\nPomBase now uses InterPro Version 73.0, which integrates 1,531 new methods from the CATH-Gene3D (122), CDD (330), PANTHER (1075), Pfam (2), PROSITE profiles (1) and TIGRFAMs (1) databases, and covers 81.2% of UniProt Knowledgebase release 2019_02.\n\nSee the news item at InterPro for additional information, including release notes.\n\nS. pombe included in Gene Info browser extension\n\n2019-04-16\n\nS. pombe gene information is now included in the Gene Info extension (GIX) for the Chrome and Firefox web browsers. GIX allows you to retrieve information about a gene product directly on any webpage simply by double clicking an official gene name, synonym or supported accession. Searching or double-clicking on text terms retrieves gene function annotation, GO terms, external database links, and interaction data drawn from BioGRID and IntAct. Retrieved gene names are automatically hyperlinked for rapid recursive searches.\n\nGeneInfo is fully open source, available online at GitHub. Tutorial videos, a step-by-step guide, and download links for Firefox Add-ons and the Chrome web storeare available online. GeneInfo was developed by James Knight in the Gingras Lab at the Lunenfeld-Tanenbaum Research Institute in Toronto, Canada.\n\nIntegrated motif search\n\n2019-03-19\n\nThe PomBase motif search has been fully integrated into the website, and allows users to find protein motifs and send them directly to the PomBase advanced search.\n\nICYGMB 2019 - registration open\n\n2019-03-13\n\nRegistration is now open for the 29th International Conference on Yeast Genetics and Molecular Biology (ICYGMB), which returns to Gothenburg, Sweden, August 18-22, 2019.\n\nYeast2019 is the meeting of the international yeast research community where the latest, and even unpublished results are exchanged, and new projects, alliances, and collaborations are founded. Featuring 55 confirmed speakers including keynote lectures by Susan Gasser, Roger Kornberg and Frederick Roth, this conference will contain important news and information for all yeast researchers. A do-not-miss-event.\n\nGO slim for any S. pombe gene list\n\n2019-03-05\n\nPomBase’s advanced search now allows you to retrieve GO slim annotations for any set of search results. To find GO slim annotations for your own list of S. pombe genes, use the advanced search “Gene names and IDs” option, and then use the “Slim” button on the search results page.\n\nSee the fission yeast GO slim page and the advanced search documentation for more information.\n\nSouth Eastern Regional Yeast Meeting (SERYM) - registration open\n\n2019-03-04\n\nRegistration is now open for the 26th annual South Eastern Regional Yeast Meeting (SERYM), which will be held April 12-14, 2019, in Atlanta, GA, USA.\n\nFission yeast’s own Susan Forsburg is the keynote speaker. The meeting brings together researchers who use any type of yeast as a model system, covering diverse, interdisciplinary topics from strategies for treatment of fungal disease to modeling human disease in yeast.\n\nIcon: SERYM 2019\n\nInternational Cell Cycle meeting - registration open\n\n2019-02-27\n\nRegistration is now open for the Inaugural Trieste Cell Cycle Meeting, which will be held June 3-6, 2019, in Trieste, Italy.\n\nThis is the first of a planned series of biennial cell cycle meetings that will take place in Europe, and will alternate with the Salk Cell Cycle meetings held on the US west coast.\n\nOrganisers Rob de Bruin, Snezhana Oliferenko, Rosella Visintin and Peter Thorpe hope to see you there!\n\nIcon derived from meeting image; credit: Chantal Roubinet, Baum lab\n\nPublished: Hidden in plain sight: What remains to be discovered in the eukaryotic proteome?\n\n2019-02-20\n\nOur analysis of conserved unknown proteins has now been published in Open Biology. In it, PomBase curators consider the challenges and opportunities that conserved, but persistently unstudied, proteins pose for diverse areas of basic and applied biology. We develop metrics to define unknown lists, provide unknown inventories for human and yeast, and classify S. pombe unknowns by numerous orthogonal attributes, all with a view to drawing attention to the unknowns to alleviate their neglect.\n\nPombe 2019 - registration open\n\n2019-02-15\n\nRegistration for the 10th International Fission Yeast Meeting is now open!\n\nThe conference will take place July 14-19, 2019, in Barcelona, Spain. Early registration closes on April 15th — or when capacity is reached. Please see the conference website for more information, including registration final deadline and costs (some travel grants are available), abstract submission, programme, accommodation, and logistics.\n\nVal Wood wins Biocuration society award\n\n2019-02-12\n\nCongratulations to PomBase project leader Val Wood, who has received the 2019 Exceptional Contributions to Biocuration Award from the International Society for Biocuration. Read more at the ISB site\n\nImproved disease association dataset released\n\n2019-01-09\n\nWe are pleased to announce the release of our improved human disease mappings dataset. This dataset connects human disease causing genes to their S. pombe orthologs.\n\nDiseases are now mapped to the Disease Ontology (DO) and the dataset has been extended by data from Malacards. All disease associations can be accessed from the top level disease page. A disease slim has been created to facilitate browsing of disease categories. Currently, 907 S. pombe genes are associated with disease (up from 610 in the original dataset). This number is due to increase as mappings are still in progress.\n\nMany thanks to DO and Malacards for help in improving this annotation set. Icon courtesy of Julie McMurry.\n\nMitochondrial GO annotation update\n\n2018-12-17\n\nResponding to increasing interest in mitochondrial biology, especially relating to ageing, neurogenerative diseases, and processes at the ER-mitochondrion interface, we have reviewed S. pombe mitochondrial GO annotations. Although there is still relatively little fission yeast-derived experimental data in this area, we have refined many inferred annotations for mitochondrial complexes and sub-components as well as some for processes.\n\nYou can see all 753 S. pombe mitochondrial annotations on the ontology term page for mitochondrion (GO:0005739).\n\nIcon courtesy of Reactome.\n\nNew nucleosome occupancy maps loaded\n\n2018-12-03\n\nWe have loaded the nucleosome occupancy maps as described in González et al. (2016) PMID: 27662899. This dataset was generated using the paired-end sequencing protocol of Illumina and thus those maps are of higher resolution than those made with single-end (SE) sequencing hosted in the browser since before.\n\nHere is a link that loads the tracks in PomBase JBrowse. And here is a link to our JBrowse quickstart guide.\n\nMany thanks to Paco Antequera for sending us the bigwig files! If you would like us to load any datasets then please get in touch.\n\nSee your genes in a QuiLT\n\n2018-11-21\n\nPomBase now offers a new way to display gene lists graphically based on multiple orthogonal annotation types — the Quick Little Tool (QuiLT) for visualisation.\n\nInspired by our recent analysis of conserved unstudied proteins (see figures 4 and S1 in the manuscript at bioRxiv), QuiLT allows you to create a similar figure for any gene list you create or import using the advanced search. To use QuiLT, follow the link to your search results, then click the “Visualise” button. QuiLT visualisation is also available from the PomBase pages that list genes annotated to an ontology term, and on the Priority unstudied genes page.\n\nTo see the Unknowns dataset in QuiLT, visit the unknowns results page and click “Visualise”.\n\nThe QuiLT display is interactive, and you can:\n\n-  Highlight subsets of the list, and filter the display\n-  Toggle annotation types on and off\n-  Reorder the list to focus on features of most interest\n-  Download the image\n\nSee the QuiLT documentation for more information, and contact the curators if you have comments, questions or suggestions.\n\nMany thanks to our star (and only) programmer, Kim Rutherford, for developing QuiLT.\n\nFission yeast transmembrane transport overhaul\n\n2018-11-20\n\nThe Gene Ontology “transmembrane transport” branch has recently been substantially revised. In line with these revisions, PomBase has standardised gene product descriptions for transporters, and overhauled GO annotations to be as complete and comprehensive as possible based on current knowledge.\n\nIcon courtesy of Reactome.\n\nHidden in plain sight: What remains to be discovered in the eukaryotic proteome?\n\n2018-11-17\n\nIn a new publication, PomBase curators consider the challenges and opportunities that conserved, but persistently unstudied, proteins pose for diverse areas of basic and applied biology. To draw attention to these proteins, we develop metrics to define unknown lists, provide unknown inventories for human and yeast, classify S. pombe unknowns by numerous orthogonal attributes, and speculate about reasons for their neglect.\n\nA pre-publication manuscript is available at bioRxiv.\n\nPomBase in your pocket\n\n2018-11-14\n\nOur usage statistics informed us that over 20% of devices accessing PomBase are smartphones or tablets. We therefore spent some time optimizing the display for small screens. We hope that you will continue to enjoy PomBase on the go!\n\nCelebrating 20 years of GO\n\n2018-11-08\n\nPomBase curators are major contributors to the Gene Ontology (GO) project — ontology content, annotations, and QC procedures — and co-authors on the new GO NAR Database Issue paper.\n\nWe recommend citing the GO and PomBase NAR papers when you use GO data in your analyses.\n\nRNA central and PomBase\n\n2018-11-06\n\nRNAcentral is a comprehensive database of non-coding RNA sequences. PomBase is an RNAcentral Consortium member, and all of the curated non-coding RNAs from PomBase will be available in RNAcentral soon. For more information, see their recent NAR Database Issue paper, as well as current search results for S. pombe RNAs.\n\nNew PomBase genomic region graphics\n\n2018-10-23\n\nPomBase gene pages now use interactive graphics from PomBase JBrowse to depict the genomic region around the gene. Drag to scroll left and right, double-click to zoom in, shift-double-click to zoom out, and click a feature to see details in a popup. The “Full-screen view” link in the corner opens the fully functional JBrowse in a new tab or window. Reloading a gene page restores the display to the default location and zoom level.\n\nPomBase NAR Database Issue\n\n2018-10-15\n\nOur NAR database update “PomBase 2018: user-driven reimplementation of the fission yeast database provides rapid and intuitive access to diverse, interconnected information” is now available. We have updated the Citing PomBase to recommend citing this new paper. Thank you all for guiding the development of the new, improved PomBase, and for your continued usage, curation contributions, and suggestions!\n\nFungal Pathogen Genomics Course 2019 - registration open\n\n2018-10-10\n\nRegistration for the 2019 Fungal Pathogen Genomics Course is now open. The course is hosted by Wellcome Genome Advanced Courses and Scientific Conferences, and will take place May 7-12, 2019, at the Wellcome Genome Campus, Hinxton, UK. Course content provides hands-on training on how to: - Take advantage of unique tools offered by FungiDB, EnsemblFungi, PomBase, SGD/CGD, and MycoCosm/JGI; - Develop testable hypotheses; - Investigate transcriptomics, proteomics and genomics datasets across multiple databases and different user interfaces. Please see the course website for more information, including how to apply, costs (limited bursaries are available), programme, and logistics.\n\nTranscript tracks from Atkinson et al. (2018) loaded\n\n2018-10-06\n\nWe are very pleased to announce that we have loaded the transcript tracks from Atkinson et al. (2018) into the PomBase JBrowse genome browser. For a brief introduction to getting started with PomBase JBrowse, please see our documentation page. If you have published data that you would like to see hosted, please get in touch.\n\npombelist changes\n\n2018-08-31\n\nThe pombe community mailing list, “pombelist”, is now hosted by the University of Cambridge. The new address for posting messages is pombelist@pombase.org. The link to subscribe has also changed.\n\nNew genome browser tracks\n\n2018-05-28\n\nWe are very pleased to announce that we have loaded a number of new datasets into the PomBase [JBrowse genome browser (https://www.pombase.org/jbrowse/). These include:\n\n-  Thodberg et al. (2018) - CAGE-defined transcription start sites across 5 different conditions\n-  Yadav et al. (2012) - G(x) scores specifying the amount of free energy needed to melt base pairs in the DNA duplex at different genomic locations\n-  A PomBase-generated dataset of promoter elements across the genome (computational matching of the consensus promoter sequences to the reference DNA sequence)\n-  Intron branch points from Bitton et al. (2014) which was also available in the Ensembl browser.\n\nFor anyone wanting a quick introduction to our genome browser, Antonia Lock has written “Getting started with PomBase JBrowse”, a basic guide that covers loading tracks, navigating the browser, what metadata we provide, and more.\n\nNew book chapter about PomBase\n\n2018-05-22\n\nPomBase has a new book chapter in Eukaryotic Genomic Databases (Methods and Protocols). This chapter provides insight into the curation philosophy and data organization at PomBase, and provides a guide to using PomBase tailored for infrequent visitors and anyone considering extending their research to include S. pombe. The chapter is free to download courtesy of the Wellcome Trust.\n\nPomBase releases JBrowse\n\n2018-04-16\n\nPomBase has now implemented JBrowse, from the GMOD project, as its genome browser. The new browser offers a number of improvements over the old:\n\n-  Quick, responsive scrolling and zooming\n-  Simple track selection interface\n-  Intuitive controls\n-  Simplified data submission pipeline behind the scenes\n-  More informative track metadata\n\nIn memory of André Goffeau\n\n2018-04-05\n\nSadly, PomBase staff and the fission yeast community note the death of André Goffeau on April 2, 2018. In addition to initiating and coordinating the sequencing of the budding yeast genome, Prof. Goffeau will be remembered for his contributions to the fission yeast genome project and for his knowledge, leadership, and friendship.\n\nCongratulations to GSA award winners\n\n2017-11-24\n\nThe Genetics Society of America (GSA) has announced two award winners familiar to the model organism database world:\n\n-  Ira Herskowitz Award: Mike Cherry, Stanford University\n-  Lifetime Achievement Award: Steve Oliver, University of Cambridge\n\nThe awards will be presented at the next Yeast Genetics Meeting, at Stanford University in August 2018. Congratulations and thanks to Mike and Steve!\n\nNew, improved PomBase goes live\n\n2017-10-24\n\nThe new PomBase web site, which has been under development during 2017, has been released. The new site features:\n\n-  Nightly data updates\n-  New publication pages\n-  New genotype pages\n-  Improved ontology term pages\n-  Improved summary views for annotation displays\n-  Phenotype annotation display filtering\n-  Faster querying in the advanced search\n-  Front page research and community curation highlights\n-  Streamlined back-end data storage and retrieval\n\nWe thank the members of the fission yeast research community who have followed its progress via the preview site, and welcome feedback from all users.\n\n9th International Fission Yeast Meeting - early registration closes soon\n\n2016-12-11\n\nReminder: early registration for the 9th International Fission Yeast Meeting in Banff closes Dec. 31, 2016. Please see the conference website at www.pombe2017.com for details.\n\n9th International Fission Yeast Meeting registration open\n\n2016-10-31\n\nRegistration for the 9th International Fission Yeast Meeting is now open. The meeting will be held in Banff, Canada from May 14-19, 2017. Early registration closes Dec 1, 2016! Please see our website at www.pombe2017.com for details. We look forward to seeing you in Banff!\n- Conference Organizers: Dallan Young, Gordon Chua, Paul Young\n\nPomBase data update 2016-10-19\n\n2016-10-19\n\nWe have updated the data available on the PomBase web site to include manual curation through September 11, 2016.\n\nShow your support for database funding\n\n2016-06-27\n\nIn response to planned cuts to database funding, leading model organism researchers have prepared an open letter to NIH Director Dr. Francis Collins to demonstrate support for the independent community-focused databases that are essential to their work. Although PomBase is not directly funded by NIH, we collaborate extensively with those that are, including the GO Consortium and several model organism databases.\nThe Genetics Society of America website where the letter can be viewed and signed is at http://www.genetics-gsa.org/MODsupport\nPlease sign the letter to add your voice in support of the databases that help make your research possible. For more information, we recommend an email that Mike Cherry sent to the GO-Friends mailing list, archived at https://mailman.stanford.edu/pipermail/go-friends/2016-June/002355.html\n\nOur model organism database commentary\n\n2016-06-15\n\nSeveral of the PomBase staff, joined by our advisor Sir Paul Nurse, have published a Comment in BMC Biology briefly describing the importance of model organism databases to the success of modern biomedical research:\nOliver SG, Lock A, Harris MA, Nurse P, Wood V. 2016. Model organism databases: essential resources that need the support of both funders and users.\nBMC Biol. 2016 14(1): 49. doi: 10.1186/s12915-016-0276-z. PMID:27334346\n\nPomBase data update 2016-05-31\n\n2016-05-31\n\nWe have updated the data available on the PomBase web site to include manual curation through May 12, 2016.\n\nPomBase data update 2016-05-09\n\n2016-05-09\n\nWe have updated the data available on the PomBase web site to include manual curation through April 8, 2016.\n\nPomBase data update 2016-04-11\n\n2016-04-11\n\nWe have updated the data available on the PomBase web site to include manual curation through March 9, 2016.\n\nImportant: We have corrected a problem that made erroneous interaction data and literature appear on some gene pages.\n\nThe gene pages now include interaction data from the Vo et al. proteome-wide study (curated by BioGRID and imported into PomBase):\nVo TV et al. 2016. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Cell 164(1-2): 310-23. doi: 10.1016/j.cell.2015.11.037 PMID:26771498.\n\nThe genome browser now includes transcriptome data published in:\nEser P, Wachutka L, Maier KC, Demel C, Boroni M, Iyer S, Cramer P, Gagneur J. 2016. Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Mol Syst Biol. 12(2): 857. doi: 10.15252/msb.20156526 PMID:26883383.\n\nPomBase data update 2016-02-11\n\n2016-02-11\n\nWe have updated the data available on the PomBase web site to include manual curation through January 25, 2016.\nThe genome browser includes variation data, in tracks under “Variation”, from natural S. pombe isolates, published in:\nJeffares DC et al. 2015. The genomic and phenotypic diversity of Schizosaccharomyces pombe. Nat Genet. 47(3): 235-241. doi:10.1038/ng.3215 PMID:25665008\n\nNew files are now available from the PomBase FTP site, and are linked from pages in the Download Datasets area:\n\n-  Non-coding RNA sequence feature coordinates (available via the Data Mappings page);\n-  Protein features, such as domains and family assignments (available via the Protein Datasets page);\n-  Protein modification annotations (also in Protein Datasets).\n\nThe New and Removed Genes page has been updated to reflect recent deletions and merges.\nNote: Ontology graph views are no longer available in the genome browser, so links have been removed from the GO, FYPO, and modification tables on the gene pages. For GO and FYPO, links to external ontology browsers that offer graphical views are available on the Ontology Term pages.\n\nPomBase data update 2015-12-02\n\n2015-12-02\n\nWe have updated the data available on the PomBase web site to include manual curation through November 9, 2015, including 340 community-curated publications.\n\nNew Advanced Search features\n\n2015-12-02\n\nWe have introduced new features to the Advanced Search:\n\n-  There are now two query reuse options: store a query in your web browser cache, or download a JSON file that can be uploaded later to re-run.\n-  You can now query for genes that interact genetically or physically with a specified gene.\n-  The FYPO query now offers options to choose nulls (deletions or disruptions), wild-type overexpression, or all alleles. The search results will include any genes that have an allele that matches the allele criteria and the chosen phenotype.\n\nNew genetics primer for fission yeast\n\n2015-10-19\n\nA new genetics primer, aimed at researchers interested in using fission yeast as a model system, has recently been published. The primer includes a brief history of fission yeast research, an introduction to available genetic tools, and the use of PomBase for data analysis\n\nHoffman CS, Wood V, Fantes PA. (2015) An Ancient Yeast for Young Geneticists: A Primer on the Schizosaccharomyces pombe Model System. Genetics 201:403-423. PMID:26447128 DOI:10.1534/genetics.115.181503\n\nPomBase data update; viability summary correction alert\n\n2015-09-28\n\nWe have updated the data available on the PomBase web site to include manual curation through September 6, 2015.\n\nErrors in the previous FYPOviability.tsv file have been corrected, and we recommend that all users update this file, especially those who downloaded it earlier in September 2015.\n\nPomBase data update with multi-allele phenotypes\n\n2015-09-03\n\nWe have updated the data available on the PomBase web site to include manual curation through August 13, 2015, including 300 community-curated publications.\n\nPomBase gene pages now include multi-allele phenotype annotations (i.e. phenotypes of double mutants, triple mutants, etc.). New sub-sections of the gene pages display multi-allele phenotypes at the population and individual cell level, paralleling the organisation of the single allele phenotype display. Compact and full views are available; both show phenotypes with the relevant genotypes and the alleles that make them up, and the full view adds details for evidence, expression, conditions, and references.\n\nThe genome browser now includes data tracks for two more publications:\nDNA polymerase usage from:\nDaigaku Y, Keszthelyi A, Müller CA, Miyabe I, Brooks T, Retkute R, Hubank M, Nieduszynski CA, Carr AM. 2015. A global profile of replicative polymerase usage. Nat Struct Mol Biol. 2015 Mar;22(3):192-8. doi: 10.1038/nsmb.2962 PMID:25664722\nPromoters and transcription start sites from:\nLi H, Hou J, Bai L, Hu C, Tong P, Kang Y, Zhao X, Shao Z. 2015. Genome-wide analysis of core promoter structures in Schizosaccharomyces pombe with DeepCAGE. RNA Biol. 2015;12(5):525-37. doi: 10.1080/15476286.2015.1022704 PMID:25747261\n\nCodon adaptation index (CAI) values are now included in the Protein Properties section of the gene pages and in the downloadable PeptideStats.tsv file. A file of amino acid composition data is also available from the FTP site and the Protein Datasets page.\n\nThe gene page section that was formerly misnamed “species distribution” is now called “taxonomic conservation”.\n\nPomBase data update 2015-06-16\n\n2015-06-16\n\nWe have updated the data available on the PomBase web site to include manual curation through May 26, 2015, including 270 community-curated publications. See you at Pombe 2015 in Kobe!\n\nCanto downtime & new version\n\n2015-05-26\n\nCanto, PomBase’s literature curation tool, will be unavailable for approximately 3 weeks starting at 12:00 midnight UK time (BST) tonight, 27 May 2015, while we deploy an upgraded version.\nThe upgraded Canto will feature an entirely new interface for annotating multi-allele phenotypes and the corresponding genotypes, as well as improved workflows for single-allele phenotypes, GO, etc. All existing annotations will be retained, and users can resume curation using the new and improved features in any unfinished sessions when Canto is back online.\nWe will announce when the new version of Canto is released to the public.\n\nPomBase data update 2015-05-26\n\n2015-05-26\n\nWe have updated the data available on the PomBase web site to include manual curation through May 8, 2015, including 265 community-curated publications.\n\nPombe 2015 travel fellowships\n\n2015-04-23\n\nApplications are now being accepted for fellowships to provide financial support for students and postdocs attending the 8th International Fission Yeast Meeting in Kobe, Japan. To apply, follow the instructions sent to the pombase mailing list. The deadline is may 17, 2015 (same as the registration deadline).\n\nPomBase data update 2015-04-19\n\n2015-04-19\n\nWe have updated the data available on the PomBase web site to include manual curation through April 7, 2015, including 260 community-curated publications.The Advanced Search now supports queries for proteins with a specified number of transmembrane domains.\n\nPombe 2015 poster abstract deadline extended\n\n2015-04-19\n\nThe abstract submission deadline for the 8th International Fission Yeast Meeting in Kobe, Japan has been extended until midnight Friday, April 24 for posters only. Registration is open until May 17.\n\nPombe 2015 abstract deadline approaching\n\n2015-04-09\n\nAbstracts are due on Sunday, April 19, 2015 for the 8th International Fission Yeast Meeting in Kobe, Japan. Registration will remain open until May 17, but the abstract submission deadline cannot be extended.\n\nPomBase data update 2015-03-23\n\n2015-03-23\n\nWe have updated the data available on the PomBase web site to include manual curation through March7, 2015, including 250 community-curated publications.The autocomplete feature of the Advanced Search ontology term filter has been improved with respect to response time and relevance of suggested terms.\n\nPombe 2015 registration now open\n\n2015-02-26\n\nRegistration for Pombe 2015: 8th International Fission Yeast Meeting is now open at the conference web site, https://amarys-jtb.jp/web/Pombe2015/index.html\n\nThe registration deadline is 17 May 2015.\n\nThanks to Yasushi Hiraoka for this item.\n\nPomBase data update 2015-02-16\n\n2015-02-16\n\nWe have updated the data available on the PomBase web site to include manual curation through February 2, 2015, including 245 community-curated publications. On the gene pages, the interaction tables now provides a bit of descriptive text for each annotation, indicating the nature and direction of the interaction.\n\nPomBase data update 2015-01-26\n\n2015-01-26\n\nWe have updated the data available on the PomBase web site to include manual curation through January 12, 2015, including 240 community-curated publications. The gene page Phenotype section now features a compact default display. A downloadable “viability summary” data file is now available. The PomBase BLAST server has incorporated interface changes made Ensembl-wide.\n\nNew compact GO annotation display\n\n2014-12-10\n\nTo make the Gene Ontology (GO) annotations easier to read on PomBase gene pages, we have introduced a new, streamlined display that presents just the essentials. The summary shows the term name (hyperlinked to the ontology term page), the count of genes annotated to the term, and any annotation extensions. All of the previously visible annotation details are still available – simply click the “Summary” button to switch to the “Full” view. Or click the “+” and “-” icons to expand or collapse the annotation to a single term.\n In addition, the top of the Biological Process table now lists any GO slim terms applicable to the gene.\n\nesyN network visualizations in PomBase\n\n2014-12-10\n\nPomBase has implemented network visualisations for fission yeast in esyN, using data curated by BioGRID and PomBase. esyN is a web-based tool for building, sharing, and viewing network data developed by Dan Bean and Giorgio Favrin in the Cambridge Systems Biology Centre, University of Cambridge, UK.\nOn gene pages, we have links to gene-specific interaction networks in esyN in the table headers of the Interactions sections:\n\n-  The Genetic Interactions section links to all interactions centred on the gene and curated in BioGRID\n-  The Physical interactions section has links to two datasets:\n -  All physical interactions curated in BioGRID for the gene\n -  Interactions for the gene in the PomBase High Confidence Physical Interaction Network (HCPIN)\n\nWe also have esyN links on the GO Slim page and on ontology term pages for GO Slim biological process terms. Each GO Slim term links to the HCPIN physical interaction network in esyN (for example, see the “regulation of mitotic cell cycle” network).\n\nPomBase data update 2014-11-12\n\n2014-11-12\n\nWe have updated the data available on the PomBase web site to include manual curation through October 27, 2014, including 225 community-curated publications. The gene page Phenotype section now includes data from the high-throughput microscopy analysis of viable deletion mutants reported in:\nGraml V, Studera X, Lawson JL, Chessel A, Geymonat M, Bortfeld-Miller M, Walter T, Wagstaff L, Piddini E, Carazo-Salas RE. A Genomic Multiprocess Survey of Machineries that Control and Link Cell Shape, Microtubule Organization, and Cell-Cycle Progression. Dev Cell. 2014 Oct 27;31(2):227-39. doi: 10.1016/j.devcel.2014.09.005 PMID:25373780. Links to the accompanying SYSGRO resource have been added to the External References section of the gene pages.\n\nThe genome browser now includes tracks for intron branch point data from:\n\nBitton DA, Rallis C, Jeffares DC, Smith GC, Chen YY, Codlin S, Marguerat  S, Bähler J. LaSSO, a strategy for genome-wide mapping of intronic  lariats and branch points using RNA-seq. Genome Res. 2014 Jul;24(7):1169-79. doi: 10.1101/gr.166819.113 PMID:24709818.\n\nWe have greatly improved search results for GO and FYPO annotations: both now follow more relationship types within the ontology to retrieve genes annotated to a term. The PomBase GO search now includes the regulates relationships, so its search results are consistent with those in the GO Consortium’s AmiGO browser. The FYPO search now uses has_part, has_output, and output_of as well as is_a and part_of. The Phenotype section now includes a highlighted sub-header that indicates whether a deletion mutant is viable or inviable. A file of protein complex subunits is available for download, and numerous smaller improvements have been made in the gene pages and static pages.\n\nPomBase data update 2014-09-16\n\n2014-09-16\n\nWe have updated the data available on the PomBase web site to include manual curation through August 30, 2014. Community curation now covers over 200 papers.\n\nPomBase data update 2014-08-18\n\n2014-08-18\n\nWe have updated the data available on the PomBase web site to include manual curation through August 8, 2014. Community curation now covers over 190 papers. Gene pages now include links to the S. pombe PeptideAtlas, a database of peptides identified in tandem mass spectrometry proteomics experiments.\n\nPomBase data update 2014-07-17\n\n2014-07-17\n\nWe have updated the data available on the PomBase web site to include manual curation through July 8, 2014. The gene pages also now display protein modification data from an additional large-scale dataset:\n\nKoch A, Krug K, Pengelley S, Macek B, Hauf S. 2011. Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast. Sci Signal. 4(179): rs6 doi: 10.1126/scisignal.2001588 PMID:21712547\nWe have also made corrections to some residue positions affected by sequence updates in one of the modification datasets we added last month:\n\nCarpy A, Krug K, Graf S, Koch A, Popic S, Hauf S, Macek B. 2014. Absolute proteome and phosphoproteome dynamics during the cell cycle of fission yeast. Mol Cell Proteomics. 2014 Apr 23. [Epub ahead of print] PMID:24763107\n\nPomBase data update 2014-07-08\n\n2014-07-08\n\nWe have updated the data available on the PomBase web site. The data now includes manual curation through June 6, 2014. In other improvements, a downloadable file of intron sequence data (FASTA format) is now available, and phenotypes are now included in the Target Of section on gene pages.\n\nThe gene pages also now display protein modification data from two large-scale datasets:\n\n-  Wilson-Grady JT, Villén J, Gygi SP. 2008 .Phosphoproteome analysis of fission yeast. J Proteome Res. 2008 Mar;7(3):1088-97. doi:10.1021/pr7006335. PMID:18257517\n-  Carpy A, Krug K, Graf S, Koch A, Popic S, Hauf S, Macek B. 2014. Absolute proteome and phosphoproteome dynamics during the cell cycle of fission yeast. Mol Cell Proteomics. 2014 Apr 23. [Epub ahead of print] PMID:24763107\n\nLink updated 2021-02-04\n\nGene Ontology publication on annotation extensions\n\n2014-06-29\n\nPomBase was an early adopter of annotation extensions, which add spatial, temporal, or substrate/target details to GO annotations. The GO Consortium has now published a paper describing its implementation of annotation extensions, in which PomBase examples and its gene page display figure prominently:\n\nHuntley, R.P. et al. (2014) A method for increasing expressivity of Gene Ontology annotations using a compositional approach. BMC Bioinformatics 2014, 15:155. doi:10.1186/1471-2105-15-155 PMID:24885854\n\nPomBase data update 2014-05-15\n\n2014-05-15\n\nWe have updated the data available on the PomBase web site. The data now includes manual curation through April 28, 2014. Transcriptome data from Margeurat et al (2012) is now available as Ensembl Browser tracks.\n\nThank you to all who have done, or are doing, paper curation in Canto. Over 159 community-curated papers are now included in PomBase.\n\nThere are a number of routes to accelerate your data into PomBase, (either through community curation, or by supplying HTP sequence, modification or phenotype data in one of our specified formats), see http://www.pombase.org/submit-data for more details.\n\nAs usual, please don’t hesitate to alert us of any other problems with data or site performance, or if you have any questions.\n\nSincerely yours,\nThe PomBase Staff\n\nPomBase data update 2014-03-20\n\n2014-03-20\n\nData on the PomBase web site now includes manual curation through February 24, 2014. Human orthologs that went missing from gene pages have been restored, and other small improvements have been made to gene pages. Community curation now covers over 130 publications.\n\nPomBase data update 2014-02-20\n\n2014-02-20\n\nWe have once again updated the data available on the PomBase web site. The data now includes manual curation through January 10, 2014, and covers over 100 papers that have been curated in Canto by community members. We again thank all who have contributed curation via Canto.\n\nWe have made some improvements to the gene pages. Highlights:\n\n-  The Sequence section now has links to NCBI BLAST as well as Ensembl BLAST.\n-  The External References section now links to the Pomb(A) polyadenylation viewer.\n\nIn the genome browser, new data tracks are now available for data from these publications:\n\n-  Rhind N, [and many more]. 2011. Comparative functional genomics of the fission yeasts. Science 332(6032):930-6. doi: 10.1126/science.1203357. PMID:21511999\n-  Schlackow M, Marguerat S, Proudfoot NJ, Bähler J, Erban R, Gullerova M. 2013. Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe. RNA. 19(12):1617-31. doi:10.1261/rna.040675.113. PMID:24152550\n-  Soriano I, Quintales L, Antequera F. 2013. Clustered regulatory elements at nucleosome-depleted regions punctuate a constant nucleosomal landscape in Schizosaccharomyces pombe. BMC Genomics. 14:813. doi:10.1186/1471-2164-14-813. PMID:24256300 (partial data;  remainder coming in the next update)\n-  Xu J, Yanagisawa Y, Tsankov AM, Hart C, Aoki K, Kommajosyula N, Steinmann KE, Bochicchio J, Russ C, Regev A, Rando OJ, Nusbaum C, Niki H, Milos P, Weng Z, Rhind N. 2012. Genome-wide identification and characterization of replication origins by deep sequencing. Genome Biol. 13(4):R27. doi:10.1186/gb-2012-13-4-r27. PMID:22531001\n\nNow that more data tracks are available, we have added some categories to the track configuration section to improve organization. Additional documentation is in preparation, and will be announced here when available.\nGenome sequences for additional Schizosaccharomyces species (S. japonicus, S. octosporus, and S. cryophilus) have recently become available in Ensembl Fungi, and the PomBase genome browser now includes comparative genomics data, with a view of region comparisons between each new genome and S. pombe.\n\nHuman ortholog data correction coming next month\n\n2014-02-19\n\nWe are about to release a data update for PomBase. Please note that there is still a problem with the human orthologs, as originally described on this list in mid-December (see archived message at http://listserver.ebi.ac.uk/pipermail/pombelist/2013/003926.html). We will correct this problem in the next PomBase release, and apologise for any inconvenience in the meantime.\n\nPomBase data update 2013-12-08\n\n2013-12-08\n\nWe have updated the data available on the PomBase web site to include manual curation through November 11, 2013. We now have future meetings available as a calendar or a list. The FAQ and some documentation pages have also been updated.\n\n2021-08-18: Updated to remove out-of-date links (events are now listed only as news items).\n\n2013 meeting mini-reviews published\n\n2013-11-24\n\nA series of mini-reviews, which were invited in association with the International Fission Yeast Meeting in London, have now been published in Biochemical Society Transactions: http://www.biochemsoctrans.org/bst/041/6/default.htm#c\n\n(Thanks to Jürg Bahler for this item)\n\nPomBase survey results available\n\n2013-11-20\n\nThe 2013 PomBase user survey closed at the end of October, and the results are available here (PDF at FTP site). Some highlights have been sent to the pombe mailing list. Many thanks to all who completed the survey.\n\nLink updated 2021-02-04\n\nNew “Target Of” gene page section\n\n2013-10-27\n\nWith the October 2013 update, gene pages now include “Target Of” annotations, which describe genes that affect the gene of interest. These annotations are essentially the reciprocal of ontology annotation extensions. Each “Target Of” annotation includes a relationship that indicates how the genes are connected, the name and product of the second gene, and a reference. Genes listed under “Target Of” may include upstream regulators or enzymes that modify the product of the gene of interest. For example, the “Target Of” annotations for cdc2 indicate that it is a substrate of, and regulated by, the kinase Wee1 and the phosphatase Cdc25 (among others). At present, “Target Of” data includes annotations derived from GO annotation extensions. We will soon extend it to include data from phenotype annotation extensions.\n\nPomBase data update 2013-10-21\n\n2013-10-21\n\nThe PomBase web site has been updated and now includes manually curated data through October 6, 2013. The number of community-curated papers continues to increase, ensuring that PomBase gene pages contain complete and up-to-date information. We are also pleased to announce that data tracks are now available in the genome browser for data from these two publications:\n\n-  Woolcock KJ, Gaidatzis D, Punga T, Bühler M. 2010. Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe. Nat Struct Mol Biol. 2011 Jan;18(1):94-9. doi: 10.1038/nsmb.1935 PMID:21151114\n-  Mata J. 2013. Genome-wide mapping of polyadenylation sites in fission yeast reveals widespread alternative polyadenylation. RNA Biol. 2013 Aug 1;10(8):1407-14. doi: 10.4161/rna.25758 PMID:23900342\n\nPomBase User Survey open\n\n2013-09-18\n\nTo guide current and future development, PomBase is now conducting a user survey, where we invite the fission yeast research community and any other PomBase users to evaluate the resources provided so far and comment on future priorities. The survey should take about 10 minutes to complete. Thank you for your participation!\n\nhttps://www.surveymonkey.com/s/NDM2BQX\n\nPomBase data update 2013-09-15\n\n2013-09-15\n\nWe have once again updated the data available on the PomBase web site. The data now includes manual curation through August 11, 2013. We are particularly pleased to note that this update includes annotations from several dozen papers curated by the S. pombe community. Many thanks to all who have done, or are doing, paper curation in Canto.\nWe also have an updated version of the S. pombe/human ortholog table available upon request.\n\nSend HTP data to PomBase\n\n2013-08-18\n\nAt the pombe 2013 meeting in London, PomBase staff received numerous requests display various published data, such as gene expression, histone modifications, etc. in the genome browser. To provide this, we now invite pombe researchers to send data: If you have published any high-throughput experiments that produced data  that can be associated with genome sequence coordinates, and thereby displayed as tracks on the PomBase genome browser, please fill out the HTP Data Submission Form. We can also accept large sets of phenotype data via the Phenotype Data Submission Form. If you have any problems or questions, contact us via the PomBase Helpdesk at any time.\n\nConnecting With PomBase\n\n2013-07-29\n\nTo complement the mailing list and twitter (@PomBase) it is now possible to follow the activities of PomBase and interact with other members of the pombe community via the new LinkedIn Group and Google+.\n\nLinks to these are also available from the front page of the PomBase.org site.\n\npombelist has moved\n\n2013-07-21\n\nUpdate: This item dates from July 2013, and the links in it no longer work. \\ Please see the Fission Yeast Community page for the current mailing list link. \\ (2020-02-18)\n\nThe pombe community mailing list, pombelist, has migrated from the Wellcome Trust Sanger Institute and is now hosted by EBI. The new address is pombelist@ebi.ac.uk (please note that the old address no longer works, and will generate an automatic notification including the new address). The link to subscribe has also been updated, and the entire archive is available at the new location.\n\nPomBase website update\n\n2013-07-18\n\nWe’d like to highlight a few improvements we’ve just made to the PomBase website. Most of the changes affect the gene pages:\n\n-  The basic information display at the top of each gene page is more compact.\n-  For ontology annotations, the number of genes annotated is now shown, in a column labeled “Count” (also, changes behind the scenes involving this data mean that pages should load faster).\n-  Annotation extensions for GO are displayed using human-friendly text instead of internal “relation” labels.\n-  The Quick Links box can now be collapsed and expanded by clicking its header.\n-  Display of modification annotations using PSI-MOD is improved.\n\nIn addition, the Motif Search output now includes standard gene names and product descriptions. As we noted in a separate message, CDS coordinate files are once again available from the Downloads, with accurate and up-to-date data.\n\nPomBase launches community curation\n\n2013-06-23\n\nAt the pombe 2013 conference in London, PomBase officially launched its community curation initiative, which allows researchers to contribute publication-based annotations directly to the database. PomBase curators invite lab heads by individual email to curate newly published papers, providing links to the online curation system and its documentation. Researchers can also initiate curation of any older fission yeast publication in PubMed. Community curation uses the open-source online tool Canto.\n\nPomBase data update 2013-06-20\n\n2013-06-20\n\nPomBase data now includes manual curation through June 9, 2013, and represents complete annotation for 664 publications (as well as partial curation of many more). A highlight of this month’s literature curation update is the addition of over 9400 phenotype annotations, representing about 95% of the phenotype data from the recently published genome-wide study of cell cycle and cell morphology (Hayles et al. Open Biology May 2013; PMID:23697806). We have also improved the display of allele details for phenotype annotations. Other changes include better support for gene synonyms in the simple search, regular updates to the UTR data files, and a number of minor adjustments to external links in the annotation data tables and the external references section.\n\nPomBase data update\n\n2013-05-20\n\nWe have updated the data available on the PomBase web site. The data now includes manual curation through 13 May, 2013.\n\nGeneDB S. pombe decommissioned\n\n2013-05-13\n\nAs of 14 May 2013, the old GeneDB database for S. pombe is no longer available. This resource consisted of static web pages, was not updated after March 2012, and not supported by an underlying relational database. The PomBase site fully supersedes GeneDB S. pombe, and provides improved infrastructure that will meet the current and future needs of the fission yeast community. Please e-mail the helpdesk if you cannot find a replacement for any GeneDB functionality in PomBase.\n\nQuantitative gene expression data available in PomBase\n\n2013-05-07\n\nWe have extended the Gene Expression section of each gene page to support the display of quantitative expression data, and are now showing data from two publications:\n\n-  Marguerat S, Schmidt A, Codlin S, Chen W, Aebersold R, BählerJ. 2012. “Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.” Cell 151:671-683.\n-  Wu JQ, Pollard TD. 2005. “Counting cytokinesis proteins globally and locally in fission yeast.” Science 310:310-314.\n\nWe will also soon refine the display of the new expression data, and can add more datasets upon request. We thank Sam Marguerat for preparing the data from both papers for inclusion in PomBase.\n\nWe have also updated the PomBase site to include manual curation through April 4, 2013, and we have updated the “all gene names” file on the PomBase ftp site. The new file is available at\nhttps://www.pombase.org/data/names_and_identifiers/gene_IDs_names.tsv\n\nLink updated 2021-02-04\n\nCarl Singer Foundation Established\n\n2013-04-11\n\nCarl Singer, who was an integral part of the yeast research community for many years, passed away on February 8, 2013. Throughout his career, Carl supported yeast research both with his engineering expertise and with his good cheer. In tribute to Carl, the Singer family has now set up The Carl Singer Foundation, a charitable foundation dedicated to supporting scientific education in the field of yeast genetics. Questions about the foundation may be directed to Harry Singer at harry [at] thecarlsingerfoundation.org.\nCarl’s family would be happy to receive memories of Carl’s life at regards [at] singerinstruments.com.\n\nH/T SGD\n\nPombe 2013: registration & abstracts by Mon 8th April\n\n2013-04-02\n\nDear Pombe Fans,\n Please remember the imminent deadline (Monday 8th April) to register and submit abstracts for Pombe 2013: http://events.embo.org/13-pombe\n Abstracts are also required from all who have already been invited to talk.\n And do book your accommodation if you haven't yet done so.\n More details are in previous email forwarded below.\n Cheers,\n -Jürg & Jacky\n From: On Behalf Of Bahler, Jurg\n Sent: 18 March 2013 17:49\n To: pombelist at sanger.ac.uk\n Subject: [Pombelist] Pombe 2013: Accommodation, registration & abstracts\n Dear Pombe Afficionados,\n Only three weeks left to register and submit abstracts for Pombe 2013, by Monday 8th April: http://events.embo.org/13-pombe\n Speakers for 10 plenary talks and all workshop talks will be selected from abstracts, and there will be attractive poster prizes.\n Payment is only requested after registration, by 10th May.\n Important: if you require accommodation, please do book this real soon now. Especially the most cost-effective student accommodation (comfortable, with private bathrooms) may not be available much longer, as it will be put on general sale shortly. Both hotels and student accommodation will sell out in June, so you have to arrange it now. Information on accommodation is available here: http://events.embo.org/13-pombe/application.html\n We will provide a number of free registrations for which you can apply during online registration (a few of which are reserved for student members of The Genetics Society: you become eligible if you join them now). The meeting is also supported by the Biochemical Society, so if you are, or become, a member you can apply to them for student bursaries or, if you have been a member for at least 1 year, also for travel grants.\n We highly appreciate all the generous contributions from our sponsors so far:\n Platinum: EMBO\n Gold: Biochemical Society, Genetics Society, Formedium, Sunrise Science Products, Singer Instruments, F1000Research, PomBase/Wellcome Trust\n Silver: MDPI - Open Access Publishing, Hybrigenics, Infors, Life Technologies, Bioneer\n Bronze: Nature Communications, m2p labs, Imsol, Open Biology\n We look very much forward to welcoming you in London this June!\n All the best,\n -Jürg & Jacky\n\nData update on PomBase web site\n\n2013-04-01\n\nWe have once again updated the data available on the PomBase web site. The data now includes manual curation through March 6, 2013.\nWe now expect to be able to update PomBase data every month, and will soon have an automated pipeline in place. We thank all of you for your patience during the long months when updates were infrequent.\nYou should also see a few small improvements in the site:\n\n-  Ontology term pages now display the text definition for each term.\n-  FASTA sequence retrieval should be quicker, and less likely to time out, for large gene lists.\n-  There has been some tidying of the display of “extension” data for GO and phenotype annotations.\n\nLast month we noted an intermittent problem with the “Reference” column display in the data tables. The occurrence of this problem should now be greatly reduced, so please let us know if you see it recurring.\nAs usual, please don’t hesitate to alert us of any other problems with data or site performance, or if you have any questions.\n\nSpeed improvements and new data on PomBase web site\n\n2013-03-01\n\nWe have updated the data available on the PomBase web site. The data now includes manual curation through December 17, 2012, and reflects complete curation of an additional 70 papers.\nWe have also made some improvements “under the hood” that should make gene page loading much faster. Please let us know if you have any problems with gene pages loading slowly or incompletely, whether or not you have reported issues in the past.\nWe are aware that there is an intermittent problem with the “Reference” column display in the data tables – sometimes a PubMed ID appears instead of an author name and year. This problem will be fixed as soon as possible. Please alert us if you notice anything else odd or wrong.\n\nNew data and new features on PomBase web site\n\n2012-11-06\n\nWe are pleased to announce that we have updated both data and web site features for PomBase.\n\nMost importantly, we have added new data types, and upgraded the gene pages to display them.\n\nWe have also added more annotations of existing data types, bringing the web site content up to September 11, 2012. The new annotations include the first contributions to come in via the new community curation system, and we thank the researchers who are participating in the initial phase of community curation.\n\nNew annotation types:\n\n-  Phenotype annotations now use the Fission Yeast Phenotype Ontology (FYPO), and include allele details, expression levels, and experimental conditions. With FYPO, more detailed phenotypes can be described, and links between terms for related phenotypes support improved phenotype searches.\n-  Many GO annotations now include “annotation extensions” that provide additional specificity. For example, extensions may capture the substrate of a catalytic activity, the cell cycle phase during which a function or process occurs, or any of several other types of supporting information for the annotation. Annotation extensions are described in more detail below.\n\nYou can see these new data types on many gene pages, such as cdc2 or pka1.\n\nNew web site features:\n\n-  Annotation display - Gene page GO and phenotype displays have been revamped to show new annotation types described above.\n-  Ontology term pages - Each ontology term ID now links to pages with information about the term and lists of genes annotated to it.\n-  Ontology graph links - GO and phenotype annotation sections now include links to graphical ontology displays in the genome browser.\n-  Sequence highlighting - Sequence download now offers an option to show colour highlighting of regions such as UTRs, introns and exons.\n-  Versions - Each gene page now shows the current data version in the format PomBase:x.y, where x is the Ensembl Genomes (EG) version, and y is the Chado version. The sequence, and sequence feature locations, remain stable within any EG version, whereas annotations change with each Chado update.\n-  Protein family information is now included in the Protein Features gene page section.\n-  The Protein Feature section includes a link to the Pfam entry for a protein.\n-  Transcript source data (e.g. for UTR coordinates) is now displayed in the Transcript Features section.\n-  A Documentation page contains links to relevant portions of the Ensembl Genomes documentation. (More documentation will be added over the coming months.)\n\nWhat are annotation extensions?\n\nAnnotation extensions are a form of supporting data that can be added GO annotations (or other ontology annotations) to capture additional details not provided by the ontology term itself.\n\nThe information in GO annotation extensions encompasses several effector-target relationships, such as\n\n-  localisation dependencies\n-  substrates of functions, e.g. targets of a protein kinase – see the has_substrate extensions on Cdc2’s “protein serine/threonine kinase” (GO:0004674) annotations\n-  activators and inhibitors\n-  regulation targets of signalling pathways or transcription factors\n\nAdditional extensions describe spatial and temporal aspects of processes. For example, several S. pombe annotations now include extensions that indicate in which phase of the cell cycle a gene product is found in a cellular component or involved in a process – see the pka1 annotations to “nucleus” (GO:0005634) and “cytoplasm” (GO:0005737).\n\nYou may also find the GO wiki page on annotation extensions informative, although it is primarily aimed at curators.\n\nAnnotation extensions can also be used with phenotype annotations. The most common usage of phenotype annotation extensions is to capture which gene, protein, etc. was used in an assay. For example, the sam5 (G441E) mutation of pka1 causes nuclear accumulation of Ste11. This is represented by annotation to the ontology term “nuclear protein accumulation” (FYPO:0000255), with the extension “assayed_using(PomBase:SPBC32C12.02)”. Extensions can also indicate expressivity or penetrance for a phenotype.\n\nPomBase web site fully live\n\n2012-07-01\n\nNote (2023-06-09): This is an archived news item about PomBase V1. See the documentation page to learn new Advanced search in PomBase V2.\n\nWe are pleased to announce that the PomBase web site, www.pombase.org, is now fully live; the preview phase has ended. The site has been updated with an assortment of new features, datatypes, and bug fixes.\n\nMore recent data, reflecting additions and changes through March 20, 2012, are now available on gene pages and in search results.\n\nThe updated site features a Gene List Search that provides behavior equivalent to GeneDB’s List Download. You can now type or paste lists into the Gene Systematic IDs and Gene Names filters, and use the Query History to combine a gene list search with other search options. For convenience, there is a direct link to a search page pre-configured to accept a list of systematic IDs available in the Find menu, on the Find page, and here: http://www.pombase.org/spombe/query/builder?filter=12\n\nThe Advanced Search also now offers:\n\n-  options to search GO, FYPO, and other ontologies by term name or ID;\n-  autocomplete for ontology term name search;\n-  ability to search for genes in a region, such as centromeres or telomeres;\n-  improved organization of filter selections.\n\nWe have also fixed a Sequence Download error reported by some users, so that the “CDS”, CDS + UTRs”, and “CDS + UTRs + Introns” options now retrieve the correct sequences.\nIn addition, numerous minor improvements have been made. Please send any questions or comments on the PomBase web site to us at <helpdesk@pombase.org>.\n\nPomBase preview launch\n\n2011-11-27\n\nA preview of PomBase, the new model organism database for the fission yeast Schizosaccharomyces pombe, has been announced to the S. pombe community for testing and feedback. For more on PomBase, see the NAR Database Issue paper (PubMed abstract) or contact the PomBase staff.\n\nPomBase NAR paper published online\n\n2011-10-27\n\nA paper describing PomBase has been published online will be included in the 2012 Database Issue of Nucleic Acids Research. Abstract and open access full text are available.\n\nGeneDB (S. pombe) now uses the latest release of the Pfam protein family database(25.0).\n\n2011-04-28\n\nSchizosaccharomyces Comparative Genome Paper Published\n\n2011-04-21\n\nA paper describing the major findings of the Schizosaccharomyces Comparative Genome Project was published today in Science Express and reported changes are included in GeneDB.\n\nFurther details are described in the pombe mailing list posts:\n\n-  Schizosaccharomyces Comparative Genome Paper Published\n-  Import of the fission yeast revisions from the Broad Institute comparative genome paper into GeneDB.\n\nGenome reappraisal reveals new genes and revised gene structures\n\n2011-02-01\n\nFurther information on the pombe mailing list.\n\nAnnotated transcription start and termination sites for fission yeast\n\n2011-01-31\n\nFurther details are available on the pombe mailing list.\n\nAnalysis of Fission Yeast Deletion Publication\n\n2010-05-15\n\nThe analysis of the fission yeast deletion collection is now published online in Nature Biotechnology.\n\nFunding for PomBase\n\n2010-02-28\n\nFunding was awarded by the Wellcome Trust for a fission yeast Model Organism Database, PomBase.\n\nFission yeast is one of the 12 key organisms of the reference genomes project\n\n2009-11-30\n\nFission yeast is one of the 12 key organisms of the reference genomes project. The goal of this project is to completely annotate twelve reference genomes so that those annotations may be used to effectively seed the automatic annotation efforts of other genome.\n\nGeneDB (S. pombe) now uses the latest update to Pfam, release 24.0\n\n2009-10-31\n\nGeneDB (S. pombe) now uses the latest update to Pfam, release 24.0 and 88.5% of fission yeast proteins now contain a match to at least one Pfam domain (increased from 83% in version 23).\n\nFission yeast in Ensembl Fungi\n\n2009-09-30\n\nThe fission yeast genome and annotation dataset is now available as part of Ensembl Fungi.\n\nGeneDB is now using Version 23 of the Pfam protein family database.\n\n2009-08-31\n\nGeneDB is now using Version 23 of the Pfam protein family database. A total of 4154 (83%) S. pombe proteins now have at least one Pfam domain or family assignment (compared to 76% for S. cerevisiae), the highest percentage coverage for any eukaryote.\n\nS. pombe GeneDB now includes “deep links” to the Biological General Repository for Interaction Datasets (BioGRID)\n\n2008-11-30\n\nS. pombe GeneDB now includes “deep links” to the Biological General Repository for Interaction Datasets (BioGRID) interaction datasets from the ‘Database Cross References’ section of the individual Gene Pages.\n\nGlobal sequence and chip study examines eukaryotic transcription\n\n2008-04-30\n\nDynamic repertoire of the fission yeast transcriptome reveals: 94% of the genome is transcribed; extensive variation in different stages and conditions; global and condition-specific coupling between splicing efficiency and transcription; confirms the majority of introns; refines ~75 gene structures; identifies 453 new transcripts 26 of which were predicted to code for proteins.\n\nThe h- mating type region has been provided\n\n2008-01-31\n\nThe h- mating type region has been provided by Xavier Marsellach and Lorena Aguilar.\n\nBaumann and Zakian labs identify telomerase RNA\n\n2007-12-31\n\nBaumann and Zakian labs identify elusive telomerase RNA (PMID:18157152 and PMID:18157149)\n\nWellcome Trust Advanced Course ’Genome-wide approaches with fission yeast\n\n2007-09-30\n\nWellcome Trust Advanced Course ‘Genome-wide approaches with fission yeast’ held in Hinxton.\n\n4th International Fission Yeast Meeting\n\n2007-05-31\n\n4th International Fission Yeast Meeting held in Copenhagen.\n\nGeneDB representation of the fission yeast data moved from contigs to chromosomes\n\n2006-12-31\n\nGeneDB representation of the fission yeast data moved from contigs to chromosomes. See the pombelist archive for details.\n\nYeast Special Issue from the 2006 European Fission Yeast Meeting\n\n2006-09-30\n\nThe October issue of the journal Yeast is a fission yeast special issue containing 13 articles and reviews commissioned as a result of the European Fission Yeast Meeting, which are FREE to download.\n\nThe first fission yeast whole proteome localization study is now published\n\n2006-06-30\n\nThe first fission yeast whole proteome localization study is now published: Matsuyama A. et al (2006): ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotech 24, 841-7.\n Fission yeast database survey\n\n2006-04-30\n\nThe fission yeast database survey is now closed. You can view the survey results here.\n\nEuropean Fission Yeast Meeting\n\n2006-03-17\n\nThe European Fission Yeast Meeting (16th-18th March 2006) and The Fission Yeast Bioinformatics workshop (15th - 16th Mar 2006) both took place at the Wellcome Trust Genome Campus in Hinxton (Cambridge, UK).\n\nComparative Genomics of Eukaryotic Microorganisms\n\n2005-11-16\n\nComparative Genomics of Eukaryotic Microorganisms:\nEukaryotic Genome Evolution, Approaches with Yeasts and Fungi\n\nThis conference took place from 12th-17th November 2005 in Sant Feliu de Guixols, Spain. Full details can be found here.\n\nSecond East Coast Regional pombe Meeting\n\n2005-11-12\n\nSecond East Coast Regional pombe Meeting\nThis meeting took place from November 11-13, 2005 in Miami Beach, Florida.\n\nGeneral Repository for Interaction Datasets\n\n2004-08-31\n\nA project to record published genetic and physical interactions is underway with Mike Tyers and the GRID group at Toronto.\n\nThe Third International Fission Yeast Meeting\n\n2004-08-29\n\nThe meeting was held at UC San Diego on August 24-29, 2004.\n\nMethods Volume 33 Issue 3\n\n2004-04-30\n\nThis issue of Methods includes 11 papers for fission yeast protocols including DNA damage checkpoint assays, cell wall analysis, TAP, nuclear envelope integrity assays, GFP imaging, TS mutant creation and plasmid use and construction. See the Methods site for details of the papers including PMIDs.\n\n2021-08-18: Updated to remove out-of-date link.\n\nRecent Genome wide surveys\n\n2003-10-31\n\nCorrelations Between Gene Expression and Gene Conservation in Fission Yeast. Mata J, Bahler J. Genome Res. 2003 Nov 12 PMID:14613978\nFELINES: a utility for extracting and examining EST-defined introns and exons. Drabenstot SD et al Nucleic Acids Res. 2003 Nov 15;31(22):e141. PMID:14602934\nGenome-wide distribution of DNA replication origins at A+T-rich islands in Schizosaccharomyces pombe. Segurado M, De Luis A, Antequera F. EMBO Rep. 2003 Nov;4(11):1048-53. Epub 2003 Oct 17. PMID:14566325\nRetrotransposons and their recognition of pol II promoters: a comprehensive survey… Bowen NJ et al Genome Res. 2003 Sep;13(9):1984-97. PMID:12952871\n\nThe ‘new’ fission yeast book is now published\n\n2003-08-31\n\nEgel, R., Copenhagen, Denmark (Ed.) The Molecular Biology of Schizosaccharomyces pombe Genetics, Genomics and Beyond ISBN:3-540-00693-1\n\nSchizosaccharomyces pombe Essential Genes: A pilot Study\n\n2003-02-28\n\nDecottignies A, Sanchez-Perez I, Nurse P Genome Res. 2003 Mar;13(3):399-406. PMID:12618370\n\nGlobal transcriptional responses of fission yeast to environmental stress\n\n2002-12-31\n\nChen D, Toone WM, Mata J, Lyne R, Burns G, Kivinen K, Brazma A, Jones N, Bähler J. Mol Biol Cell. 2003 Jan;14(1):214-29. PMID:12529438\n",
       "heading" : "News archive",
       "id" : "news/index"
    },
@@ -2269,6 +2279,16 @@
       "heading" : "Gene coordinate changes",
       "id" : "status/gene-coordinate-changes"
    },
+   {
+      "content" : "\n\nThe table below contains all changes to sequence coordinates in RNA genes. Each pair of rows corresponds to a change, with columns corresponding to:\n\n-  Date: date of the change.\n-  Systematic id: systematic id of the gene affected.\n-  Primary name: primary name of the gene affected, if it exists.\n-  Before / after change: if the value is before, the value of Coordinates corresponds to coordinates of the CDS before the change. If the value is after, the value of Coordinates corresponds to coordinates of the CDS after the change.\n-  Coordinates: see above.\n-  Comment: a comment by PomBase curators might be associated with a change.\n-  Reference: a reference (e.g. a PubMed ID) might be associated with a change.\n\nFor a list of all changes in the genome (including protein coding genes) in a similar format see:\n\n-  https://github.com/pombase/genome_changelog/blob/master/results/all_coordinate_changes_file_comments_no_type_change.tsv for changes after 23-08-2011.\n-  https://github.com/pombase/genome_changelog/blob/master/results/pre_svn_coordinate_changes_file_comments_no_type_change.tsv for previous changes.\n",
+      "heading" : "RNA gene coordinate changes",
+      "id" : "status/gene-coordinate-changes-RNA"
+   },
+   {
+      "content" : "\n\nThe table below contains all changes to coding sequence (CDS) coordinates in protein coding genes. Each pair of rows corresponds to a change, with columns corresponding to:\n\n-  Date: date of the change.\n-  Systematic id: systematic id of the gene affected.\n-  Primary name: primary name of the gene affected, if it exists.\n-  Before / after change: if the value is before, the value of Coordinates corresponds to coordinates of the CDS before the change. If the value is after, the value of Coordinates corresponds to coordinates of the CDS after the change.\n-  Coordinates: see above.\n-  Comment: a comment by PomBase curators might be associated with a change.\n-  Reference: a reference (e.g. a PubMed ID) might be associated with a change.\n\nFor a list of all changes in the genome (including UTRs of coding genes and RNA genes) in a similar format see:\n\n-  https://github.com/pombase/genome_changelog/blob/master/results/all_coordinate_changes_file_comments_no_type_change.tsv for changes after 23-08-2011.\n-  https://github.com/pombase/genome_changelog/blob/master/results/pre_svn_coordinate_changes_file_comments_no_type_change.tsv for previous changes.\n",
+      "heading" : "Protein coding gene coordinate changes",
+      "id" : "status/gene-coordinate-changes-protein-coding"
+   },
    {
       "content" : "\n\nChromosomes\n\n``\n",
       "heading" : "Genome overview",
@@ -2345,7 +2365,7 @@
       "id" : "submit-data/gene-naming-committee-members"
    },
    {
-      "content" : "\n\nPurpose of Reserving Gene Names\n\nTo avoid gene naming conflicts, the S. pombeGene Naming Committee accepts reservations for gene names that will be published imminently. This does not guarantee that no one else will use your reserved gene name, but the naming committee will actively discourage alternative usage. If we become aware of a nomenclature conflict, we will attempt to notify all parties.\n\nGuidelines for naming S. pombe genes\n\n1.  The gene name should consist of three italicized lower case letters (the gene symbol) followed by an integer (e.g. rad26). This will not be italicized in the database. (Note that a few historical gene names with four letters, or without an integer, have been grandfathered into the database, but all new standard gene names must conform to the three-letters-plus-integer pattern.)\n2.  The gene name registration form will return soon. To reserve a gene name in the meantime, please email the helpdesk and include the gene systematic ID, proposed gene name, name description, the relevant PubMed ID (if available), and any other information.\n3.  The 3-letter gene symbol should stand for a description of a phenotype, gene product or gene function. In addition, we strongly prefer that a given gene symbol have only one associated description, i.e., all genes which use a given 3 letter symbol should have a related phenotype, gene product or gene function. If a 3-letter symbol is already in use, it should not be used to describe a different class of genes. Before choosing your gene name, search PomBase for any gene name beginning with the 3-letter symbol, by entering the 3-letter name followed by an asterisk, e.g. “cdc*”. Also check the usage of the 3-letter code in S. cerevisiae at SGD.\n4.  Please include your gene name(s) in the abstracts of any relevant papers. This simplifies the task of identifying yeast gene names that are already in use.\n5.  At the time of registration, the S. pombe curator will check PubMed, GenBank/EMBL/DDBJ and the Gene Name Registry to ensure the gene name is unique. If your chosen gene name is not unique, you will be contacted and asked to select a new name.\n6.  Please check that the reserved gene name is still unique, and that the gene still has no other name used for it, before submitting a publication.\n7.  If it is discovered that your gene has been previously named, your gene name would instead become an alias (synonym) for the locus, and it and any associated references will remain searchable and linked to the standard locus name.\n8.  If you reserve a gene name prior to publication, and your reserved name is published referring to a different gene before your name usage is published, a compromise specific to the situation will be made. In most cases, you will NOT retain the use of the gene name unless you published the name first (see “Resolution of gene name conflicts” below).\n9.  If no conflicts arise, your gene name will become the standard name, and will appear on the gene page and elsewhere in PomBase.\n\nResolution of gene name conflicts\n\nGene name conflicts in which multiple names have been used to describe one gene or, conversely, one name has been applied to multiple genes, will be resolved within 12 months. Whenever possible, all interested parties will be involved in the resolution of the conflict. We recognize that each case is unique, and we will choose the most appropriate solution using the following guidelines:\n\n1.  Researcher consensus: In the first instance, if the researchers involved in the name conflict agree to a resolution that satisfies our Gene Naming requirements, this solution will be implemented.\n2.  Literature consensus: In the absence of researcher consensus, we will examine the literature for the number of name usages and the number of different research groups utilizing a particular name usage. If there is a very obvious imbalance, we will favour the predominant name usage.\n3.  Priority: In the absence of either researcher or literature consensus, we will favour the gene name usage that was first published if this is significantly earlier. However, if papers are published simultaneously (within 3 months), the pre-registered name will become the primary name.\n4.  Relevance of the name: In rare cases where none of the above guidelines apply, we may favour a particular name usage that more accurately describes a phenotype, gene product or gene function.\n",
+      "content" : "\n\nPurpose of Reserving Gene Names\n\nTo avoid gene naming conflicts, the S. pombeGene Naming Committee accepts reservations for gene names that will be published imminently. This does not guarantee that no one else will use your reserved gene name, but the naming committee will actively discourage alternative usage. If we become aware of a nomenclature conflict, we will attempt to notify all parties.\n\nGuidelines for naming S. pombe genes\n\n1.  The gene name should consist of three italicized lower case letters (the gene symbol) followed by an integer (e.g. rad26). This will not be italicized in the database. (Note that a few historical gene names with four letters, or without an integer, have been grandfathered into the database, but all new standard gene names must conform to the three-letters-plus-integer pattern.)\n2.  The gene name registration form will return soon. To reserve a gene name in the meantime, please email the helpdesk and include the gene systematic ID, proposed gene name, name description, the relevant PubMed ID (if available), and any other information.\n3.  The 3-letter gene symbol should stand for a description of a phenotype, gene product or gene function. In addition, we strongly prefer that a given gene symbol have only one associated description, i.e., all genes which use a given 3 letter symbol should have a related phenotype, gene product or gene function. If a 3-letter symbol is already in use, it should not be used to describe a different class of genes. Before choosing your gene name, search PomBase for any gene name beginning with the 3-letter symbol, by entering the 3-letter name followed by an asterisk, e.g. “cdc*”. Also check the usage of the 3-letter code in S. cerevisiae at SGD.\n4.  For non-coding RNA genes, follow these rules from Lera-Ramirez et al. 2023.\n5.  Please include your gene name(s) in the abstracts of any relevant papers. This simplifies the task of identifying yeast gene names that are already in use.\n6.  At the time of registration, the S. pombe curator will check PubMed, GenBank/EMBL/DDBJ and the Gene Name Registry to ensure the gene name is unique. If your chosen gene name is not unique, you will be contacted and asked to select a new name.\n7.  Please check that the reserved gene name is still unique, and that the gene still has no other name used for it, before submitting a publication.\n8.  If it is discovered that your gene has been previously named, your gene name would instead become an alias (synonym) for the locus, and it and any associated references will remain searchable and linked to the standard locus name.\n9.  If you reserve a gene name prior to publication, and your reserved name is published referring to a different gene before your name usage is published, a compromise specific to the situation will be made. In most cases, you will NOT retain the use of the gene name unless you published the name first (see “Resolution of gene name conflicts” below).\n10. If no conflicts arise, your gene name will become the standard name, and will appear on the gene page and elsewhere in PomBase.\n\nResolution of gene name conflicts\n\nGene name conflicts in which multiple names have been used to describe one gene or, conversely, one name has been applied to multiple genes, will be resolved within 12 months. Whenever possible, all interested parties will be involved in the resolution of the conflict. We recognize that each case is unique, and we will choose the most appropriate solution using the following guidelines:\n\n1.  Researcher consensus: In the first instance, if the researchers involved in the name conflict agree to a resolution that satisfies our Gene Naming requirements, this solution will be implemented.\n2.  Literature consensus: In the absence of researcher consensus, we will examine the literature for the number of name usages and the number of different research groups utilizing a particular name usage. If there is a very obvious imbalance, we will favour the predominant name usage.\n3.  Priority: In the absence of either researcher or literature consensus, we will favour the gene name usage that was first published if this is significantly earlier. However, if papers are published simultaneously (within 3 months), the pre-registered name will become the primary name.\n4.  Relevance of the name: In rare cases where none of the above guidelines apply, we may favour a particular name usage that more accurately describes a phenotype, gene product or gene function.\n",
       "heading" : "Fission yeast gene naming guidelines",
       "id" : "submit-data/gene-naming-guidelines"
    },
diff --git a/src/app/config/graphical_abstract_files.json b/src/app/config/graphical_abstract_files.json
index a5976727..d6defa16 100644
--- a/src/app/config/graphical_abstract_files.json
+++ b/src/app/config/graphical_abstract_files.json
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diff --git a/src/app/documentation/docs/docs.component.html b/src/app/documentation/docs/docs.component.html
index dcb54be2..01ccb23c 100644
--- a/src/app/documentation/docs/docs.component.html
+++ b/src/app/documentation/docs/docs.component.html
@@ -530,6 +530,19 @@ <h1 id="pombase-ongoing-projects">PomBase ongoing projects</h1>
 <h2 id="pombase-and-collaborative-publications">PomBase and collaborative publications</h2>
 <p>Please see the <a routerLink="/about/citing-pombase">Citing PomBase</a> page, which lists papers to cite for PomBase, the <em>S. pombe</em> genome sequence, Canto, FYPO, annotations and Compara.</p>
 <h3 id="journal-articles">Journal articles</h3>
+<div class="altmetric-embed" data-badge-type="donut" data-doi="10.1093/genetics/iyad143">
+
+</div>
+<div class="pub-citation">
+<p>Manuel Lera-Ramírez, Jürg Bähler, Juan Mata, Kim Rutherford, Charles S Hoffman, Sarah Lambert, Snezhana Oliferenko, Sophie G Martin, Kathleen L Gould, Li-Lin Du, Sarah A Sabatinos, Susan L Forsburg, Olaf Nielsen, Paul Nurse, Valerie Wood<br />
+Revised fission yeast gene and allele nomenclature guidelines for machine readability<br />
+<em>Genetics</em>, September 2023, iyad031<br />
+</p>
+</div>
+<p><a href="https://doi.org/10.1093/genetics/iyad143">10.1093/genetics/iyad143</a></p>
+<div class="clear-float">
+
+</div>
 <div class="altmetric-embed" data-badge-type="donut" data-doi="10.7554/eLife.84658">
 
 </div>
@@ -9708,6 +9721,13 @@ <h3 id="what-go-term-enrichment-how-can-i-do-it-my-genes">What is GO term enrich
 <p>“GO term enrichment” refers to analysing a gene list by finding GO terms that are significantly over- or under-represented among the annotations for the genes. Finding GO terms that are shared by genes in your list can help you find out what they have in common biologically.</p>
 <p>PomBase does not have its own GO enrichment tool, but we recommend one, and provide a bit more information, in the <a routerLink="/faq/how-can-i-find-significant-shared-go-annotations-genes-list">FAQ on GO term enrichment</a>.</p>
 
+</div>
+<div (click)="faq_navigate($event, '/faq/what-pombemine-service-url', 'What is the PombeMine service URL')" *ngIf="pageName == 'tools-and-resources' || pageName == 'what-pombemine-service-url' || pageName == 'all-faqs' || section == 'faq' && pageName == 'index'">
+<h3 id="what-pombemine-service-url">What is the PombeMine service URL</h3>
+<!-- pombase_categories: Tools and resources -->
+<p>The URL is: <code>https://www.pombase.org/pombemine/service</code></p>
+<p>This URL is needed in order to access the PombeMine API programmatically;. See the <a href="https://intermine.readthedocs.io/en/latest/web-services/">InterMine web service documentation</a> for details.</p>
+
 </div>
 <div (click)="faq_navigate($event, '/faq/what-psl-format', 'What is PSL format?')" *ngIf="pageName == 'data-submission-and-formats' || pageName == 'what-psl-format' || pageName == 'all-faqs' || section == 'faq' && pageName == 'index'">
 <h3 id="what-psl-format">What is PSL format?</h3>
@@ -9839,6 +9859,7 @@ <h3 id="contact-curators"><a routerLink="/about">Contact Curators</a></h3>
 <div *ngIf="section == 'news'">
 <app-page-contents-menu title="News" titleRoute="/news">
 
+<div class="left-menu-part left-menu-item"><a pageScroll href="#revised-fission-yeast-nomenclature-genes-and-alleles">Revised fission yeast nomenclature for genes and alleles</a></div>
 <div class="left-menu-part left-menu-item"><a pageScroll href="#accessing-list-genes-paper">Accessing the list of genes from a paper</a></div>
 <div class="left-menu-part left-menu-item"><a pageScroll href="#protein-feature-viewer-added-gene-pages">Protein feature viewer added to gene pages</a></div>
 <div class="left-menu-part left-menu-item"><a pageScroll href="#reaction-diagrams-on-term-pages">Reaction diagrams on term pages</a></div>
@@ -12191,10 +12212,27 @@ <h4 id="accessing-list-genes-paper">Accessing the list of genes from a paper</h4
 <p>It’s now possible to view the list of genes associated with a paper, using a new link on the publication pages. The gene list can then optionally be sent to the Advanced Search.</p>
 <p><a href="assets/newsfeed/genes-list-from-ref-page.png"><img src="assets/newsfeed/genes-list-from-ref-page.png" title="Publication page, highlightling the new genes link" class="screenshot" style="width:100.0%" alt="Publication page, highlightling the new genes link" /></a></p>
 
+  </div>
+  <div *ngIf="pageName == 'nomenclature-paper'">
+<h4 id="revised-fission-yeast-nomenclature-genes-and-alleles">Revised fission yeast nomenclature for genes and alleles</h4>
+<!-- pombase_flags: frontpage -->
+<!-- newsfeed_thumbnail: pombase-logo-32x32px.png -->
+<p>The improved nomenclature guidelines for fission yeast clade genes and alleles have been <a href="https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyad143/7283026">published in Genetics GSA</a>. This update introduces nomenclature guidelines for noncoding RNA genes, a significant update to the allele and genotype nomenclature guidelines originally published in 1987. We took several steps to improve machine readability that will benefit the artificial intelligence/machine learning communities, and our own community curation program.</p>
+<p><a href="https://doi.org/10.1093/genetics/iyad143">Lera-Ramírez <em>et al.</em> 2023, Revised fission yeast gene and allele nomenclature guidelines for machine readability, Genetics, 2023;, iyad143</a></p>
+<p><a href="assets/newsfeed/nomenclature_paper_for_news_big.png"><img src="assets/newsfeed/nomenclature_paper_for_news.png" title="Revised fission yeast gene and allele nomenclature guidelines for machine readability" class="screenshot" style="width:100.0%" alt="“Revised fission yeast gene and allele nomenclature guidelines for machine readability”" /></a></p>
+
   </div>
   <div *ngIf="pageName == 'index'">
 <h2 id="news-archive">News archive</h2>
 <div class="news-archive">
+<div id="2023-09-30-nomenclature-paper" class="news-item">
+<p><img loading="lazy" class="newsfeed-thumbnail" src="/assets/newsfeed/pombase-logo-32x32px.png"/></p>
+<h3 id="revised-fission-yeast-nomenclature-genes-and-alleles">Revised fission yeast nomenclature for genes and alleles</h3>
+<p><em>2023-09-30</em></p>
+<p>The improved nomenclature guidelines for fission yeast clade genes and alleles have been <a href="https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyad143/7283026">published in Genetics GSA</a>. This update introduces nomenclature guidelines for noncoding RNA genes, a significant update to the allele and genotype nomenclature guidelines originally published in 1987. We took several steps to improve machine readability that will benefit the artificial intelligence/machine learning communities, and our own community curation program.</p>
+<p><a href="https://doi.org/10.1093/genetics/iyad143">Lera-Ramírez <em>et al.</em> 2023, Revised fission yeast gene and allele nomenclature guidelines for machine readability, Genetics, 2023;, iyad143</a></p>
+<p><a href="assets/newsfeed/nomenclature_paper_for_news_big.png"><img src="assets/newsfeed/nomenclature_paper_for_news.png" title="Revised fission yeast gene and allele nomenclature guidelines for machine readability" class="screenshot" style="width:100.0%" alt="“Revised fission yeast gene and allele nomenclature guidelines for machine readability”" /></a></p>
+</div>
 <div id="2023-09-20-list-of-publication-genes" class="news-item">
 <p><img loading="lazy" class="newsfeed-thumbnail" src="/assets/newsfeed/pombase-logo-32x32px.png"/></p>
 <h3 id="accessing-list-genes-paper">Accessing the list of genes from a paper</h3>
@@ -14691,6 +14729,21 @@ <h3 id="gene-coordinate-changes">Gene coordinate changes</h3>
   </div>
   <div *ngIf="pageName == 'gene-coordinate-changes-RNA'">
 <h3 id="rna-gene-coordinate-changes">RNA gene coordinate changes</h3>
+<p>The table below contains all changes to sequence coordinates in RNA genes. Each pair of rows corresponds to a change, with columns corresponding to:</p>
+<ul>
+<li><strong>Date:</strong> date of the change.</li>
+<li><strong>Systematic id:</strong> systematic id of the gene affected.</li>
+<li><strong>Primary name:</strong> primary name of the gene affected, if it exists.</li>
+<li><strong>Before / after change:</strong> if the value is <code>before</code>, the value of <code>Coordinates</code> corresponds to coordinates of the CDS before the change. If the value is <code>after</code>, the value of <code>Coordinates</code> corresponds to coordinates of the CDS after the change.</li>
+<li><strong>Coordinates:</strong> see above.</li>
+<li><strong>Comment:</strong> a comment by PomBase curators might be associated with a change.</li>
+<li><strong>Reference:</strong> a reference (e.g. a PubMed ID) might be associated with a change.</li>
+</ul>
+<p>For a list of all changes in the genome (including protein coding genes) in a similar format see:</p>
+<ul>
+<li><a href="https://github.com/pombase/genome_changelog/blob/master/results/all_coordinate_changes_file_comments_no_type_change.tsv">https://github.com/pombase/genome_changelog/blob/master/results/all_coordinate_changes_file_comments_no_type_change.tsv</a> for changes after 23-08-2011.</li>
+<li><a href="https://github.com/pombase/genome_changelog/blob/master/results/pre_svn_coordinate_changes_file_comments_no_type_change.tsv">https://github.com/pombase/genome_changelog/blob/master/results/pre_svn_coordinate_changes_file_comments_no_type_change.tsv</a> for previous changes.</li>
+</ul>
 <table><thead><tr>
 <th>Date</th><th>Systematic id</th><th>Primary name</th><th>Before / after change</th><th>Coordinates</th><th>Comment</th><th>Reference</th>
 </thead>
@@ -14964,6 +15017,21 @@ <h3 id="rna-gene-coordinate-changes">RNA gene coordinate changes</h3>
   </div>
   <div *ngIf="pageName == 'gene-coordinate-changes-protein-coding'">
 <h3 id="protein-coding-gene-coordinate-changes">Protein coding gene coordinate changes</h3>
+<p>The table below contains all changes to coding sequence (CDS) coordinates in protein coding genes. Each pair of rows corresponds to a change, with columns corresponding to:</p>
+<ul>
+<li><strong>Date:</strong> date of the change.</li>
+<li><strong>Systematic id:</strong> systematic id of the gene affected.</li>
+<li><strong>Primary name:</strong> primary name of the gene affected, if it exists.</li>
+<li><strong>Before / after change:</strong> if the value is <code>before</code>, the value of <code>Coordinates</code> corresponds to coordinates of the CDS before the change. If the value is <code>after</code>, the value of <code>Coordinates</code> corresponds to coordinates of the CDS after the change.</li>
+<li><strong>Coordinates:</strong> see above.</li>
+<li><strong>Comment:</strong> a comment by PomBase curators might be associated with a change.</li>
+<li><strong>Reference:</strong> a reference (e.g. a PubMed ID) might be associated with a change.</li>
+</ul>
+<p>For a list of all changes in the genome (including UTRs of coding genes and RNA genes) in a similar format see:</p>
+<ul>
+<li><a href="https://github.com/pombase/genome_changelog/blob/master/results/all_coordinate_changes_file_comments_no_type_change.tsv">https://github.com/pombase/genome_changelog/blob/master/results/all_coordinate_changes_file_comments_no_type_change.tsv</a> for changes after 23-08-2011.</li>
+<li><a href="https://github.com/pombase/genome_changelog/blob/master/results/pre_svn_coordinate_changes_file_comments_no_type_change.tsv">https://github.com/pombase/genome_changelog/blob/master/results/pre_svn_coordinate_changes_file_comments_no_type_change.tsv</a> for previous changes.</li>
+</ul>
 <table><thead><tr>
 <th>Date</th><th>Systematic id</th><th>Primary name</th><th>Before / after change</th><th>Coordinates</th><th>Comment</th><th>Reference</th>
 </thead>
@@ -28296,6 +28364,7 @@ <h3 id="guidelines-for-naming-s.-pombe-genes">Guidelines for naming <em>S. pombe
 <li>The gene name should consist of three italicized lower case letters (the gene symbol) followed by an integer (e.g. rad26). This will not be italicized in the database. (Note that a few historical gene names with four letters, or without an integer, have been grandfathered into the database, but all new standard gene names must conform to the three-letters-plus-integer pattern.)</li>
 <li>The gene name registration form will return soon. To reserve a gene name in the meantime, please <a href="mailto:helpdesk@pombase.org?subject=gene%20name%20reservation">email the helpdesk</a> and include the gene systematic ID, proposed gene name, name description, the relevant PubMed ID (if available), and any other information.</li>
 <li>The 3-letter gene symbol should stand for a description of a phenotype, gene product or gene function. In addition, we strongly prefer that a given gene symbol have only one associated description, i.e., all genes which use a given 3 letter symbol should have a related phenotype, gene product or gene function. If a 3-letter symbol is already in use, it should not be used to describe a different class of genes. Before choosing your gene name, search PomBase for any gene name beginning with the 3-letter symbol, by entering the 3-letter name followed by an asterisk, e.g. “cdc*”. Also check the usage of the 3-letter code in <em>S. cerevisiae</em> at <a href="http://www.yeastgenome.org/">SGD</a>.</li>
+<li>For non-coding RNA genes, follow <a href="https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyad143/7283026#419163545">these rules</a> from <a href="https://doi.org/10.1093/genetics/iyad143">Lera-Ramirez et al. 2023</a>.</li>
 <li>Please include your gene name(s) in the abstracts of any relevant papers. This simplifies the task of identifying yeast gene names that are already in use.</li>
 <li>At the time of registration, the <em>S. pombe</em> curator will check PubMed, GenBank/EMBL/DDBJ and the Gene Name Registry to ensure the gene name is unique. If your chosen gene name is not unique, you will be contacted and asked to select a new name.</li>
 <li>Please check that the reserved gene name is still unique, and that the gene still has no other name used for it, before submitting a publication.</li>
diff --git a/src/app/front-panel-content/front-panel-content.component.html b/src/app/front-panel-content/front-panel-content.component.html
index ed1a2c07..458180fc 100644
--- a/src/app/front-panel-content/front-panel-content.component.html
+++ b/src/app/front-panel-content/front-panel-content.component.html
@@ -1,4 +1,12 @@
 <div *ngIf="panelId == 0">
+<p>Broad functional profiling of fission yeast proteins using phenomics and machine learning.</p>
+
+
+
+<p>Originally published in <a href='https://doi.org/10.7554/eLife.88229'>Elife</a>.</p>
+
+</div>
+<div *ngIf="panelId == 1">
 <p>Microtubule competition and cell growth recenter the nucleus after anaphase in fission yeast.</p>
 
 
@@ -6,7 +14,7 @@
 <p>Originally published in <a href='https://doi.org/10.1091/mbc.E23-01-0034'>Mol Biol Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 1">
+<div *ngIf="panelId == 2">
 <p>Actin-Microtubule Crosstalk Imparts Stiffness to the Contractile Ring in Fission Yeast.</p>
 
 
@@ -14,7 +22,7 @@
 <p>Originally published in <a href='https://doi.org/10.3390/cells12060917'>Cells</a>.</p>
 
 </div>
-<div *ngIf="panelId == 2">
+<div *ngIf="panelId == 3">
 <p>Tfs1, transcription elongation factor TFIIS, has an impact on chromosome segregation affected by pka1 deletion in Schizosaccharomyces pombe.</p>
 
 
@@ -22,7 +30,7 @@
 <p>Originally published in <a href='https://doi.org/10.1007/s00294-023-01268-0'>Curr Genet</a>.</p>
 
 </div>
-<div *ngIf="panelId == 3">
+<div *ngIf="panelId == 4">
 <p>RNA polymerase II CTD interactome with 3’ processing and termination factors in fission yeast and its impact on phosphate homeostasis.</p>
 
 
@@ -30,7 +38,7 @@
 <p>Originally published in <a href='https://doi.org/10.1073/pnas.1810711115'>Proc Natl Acad Sci U S A</a>.</p>
 
 </div>
-<div *ngIf="panelId == 4">
+<div *ngIf="panelId == 5">
 <p>Duf89 abets lncRNA control of fission yeast phosphate homeostasis via its antagonism of precocious lncRNA transcription termination.</p>
 
 
@@ -38,7 +46,7 @@
 <p>Originally published in <a href='https://doi.org/10.1261/rna.079595.123'>RNA</a>.</p>
 
 </div>
-<div *ngIf="panelId == 5">
+<div *ngIf="panelId == 6">
 <p>Fission yeast Dis1 is an unconventional TOG/XMAP215 that induces microtubule catastrophe to drive chromosome pulling.</p>
 
 
@@ -46,7 +54,7 @@
 <p>Originally published in <a href='https://doi.org/10.1038/s42003-022-04271-2'>Commun Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 6">
+<div *ngIf="panelId == 7">
 <p>Inorganic polyphosphate abets silencing of a sub-telomeric gene cluster in fission yeast.</p>
 
 
@@ -54,7 +62,7 @@
 <p>Originally published in <a href='https://doi.org/10.17912/micropub.biology.000744'>MicroPubl Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 7">
+<div *ngIf="panelId == 8">
 <p>Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast.</p>
 
 
@@ -62,7 +70,7 @@
 <p>Originally published in <a href='https://doi.org/10.7554/eLife.83062'>Elife</a>.</p>
 
 </div>
-<div *ngIf="panelId == 8">
+<div *ngIf="panelId == 9">
 <p>A scaffold lncRNA shapes the mitosis to meiosis switch.</p>
 
 
@@ -70,7 +78,7 @@
 <p>Originally published in <a href='https://doi.org/10.1038/s41467-021-21032-7'>Nat Commun</a>.</p>
 
 </div>
-<div *ngIf="panelId == 9">
+<div *ngIf="panelId == 10">
 <p>The SAGA histone acetyltransferase module targets SMC5/6 to specific genes.</p>
 
 
@@ -78,7 +86,7 @@
 <p>Originally published in <a href='https://doi.org/10.1186/s13072-023-00480-z'>Epigenetics Chromatin</a>.</p>
 
 </div>
-<div *ngIf="panelId == 10">
+<div *ngIf="panelId == 11">
 <p>Protein S-palmitoylation regulates different stages of meiosis in Schizosaccharomyces pombe.</p>
 
 
@@ -86,7 +94,7 @@
 <p>Originally published in <a href='https://doi.org/10.26508/lsa.202201755'>Life Science Alliance</a>.</p>
 
 </div>
-<div *ngIf="panelId == 11">
+<div *ngIf="panelId == 12">
 <p>Microtubule-mitochondrial attachment facilitates cell division symmetry and mitochondrial partitioning in fission yeast.</p>
 
 
@@ -94,7 +102,7 @@
 <p>Originally published in <a href='https://doi.org/10.1242/jcs.260705'>Journal of cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 12">
+<div *ngIf="panelId == 13">
 <p>Tschimganine has different targets for chronological lifespan extension and growth inhibition in fission yeast.</p>
 
 
@@ -102,11 +110,11 @@
 <p>Originally published in <a href='https://doi.org/10.1093/bbb/zbac051'>Bioscience, Biotechnology, and Biochemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 13">
+<div *ngIf="panelId == 14">
 <p>Contractile ring structure at nanoscale resolution. Image from <a href="https://elifesciences.org/articles/28865#video1">eLife 2017;6:e28865</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 14">
+<div *ngIf="panelId == 15">
 <p>Molecular model of fission yeast centrosome assembly determined by superresolution imaging.</p>
 
 
@@ -114,7 +122,7 @@
 <p>Originally published in <a href="http://jcb.rupress.org/content/216/8/2409">Journal of Cell Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 15">
+<div *ngIf="panelId == 16">
 <p>Structural Basis for Shelterin Bridge Assembly.</p>
 
 
@@ -122,7 +130,7 @@
 <p>Originally published in <a href="http://www.cell.com/molecular-cell/fulltext/S1097-2765%2817%2930809-2">Molecular Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 16">
+<div *ngIf="panelId == 17">
 <p>Study shows second ssDNA capture by the SMC complex during establishment of sister chromatid cohesion.</p>
 
 
@@ -130,7 +138,7 @@
 <p>Originally published in <a href='http://www.cell.com/cell/fulltext/S0092-8674(17)31501-5'>Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 17">
+<div *ngIf="panelId == 18">
 <p>Model illustrating collaborative inward force generation by kinesin-14s.</p>
 
 
@@ -138,7 +146,7 @@
 <p>Originally published in <a href='http://jcs.biologists.org/content/131/1/jcs210740.long'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 18">
+<div *ngIf="panelId == 19">
 <p>CAGE-defined Transcription Start Sites across 5 different conditions.</p>
 
 
@@ -146,7 +154,7 @@
 <p>Originally published in the <a href='https://academic.oup.com/nar/article/47/4/1671/5253058'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 19">
+<div *ngIf="panelId == 20">
 <p>The ancient claudin Dni2 facilitates cell fusion at the shmoo tip.</p>
 
 
@@ -154,7 +162,7 @@
 <p>Originally published in <a href='https://link.springer.com/article/10.1007%2Fs00018-017-2709-4'>Cellular and Molecular Life Sciences</a>.</p>
 
 </div>
-<div *ngIf="panelId == 20">
+<div *ngIf="panelId == 21">
 <p>Graph-based visualization of Hi-C datasets.</p>
 
 
@@ -162,7 +170,7 @@
 <p>Originally published in <a href='https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-018-3507-2'>BMC Research Notes</a>.</p>
 
 </div>
-<div *ngIf="panelId == 21">
+<div *ngIf="panelId == 22">
 <p>A unified model for cell size control.</p>
 
 
@@ -170,7 +178,7 @@
 <p>Originally published in <a href='http://jcb.rupress.org/content/217/5/1589'>Journal of Cell Biology</a>. Image from a <a href='http://jcb.rupress.org/content/217/5/1559'>Commentary</a> by Gerganova and Martin.</p>
 
 </div>
-<div *ngIf="panelId == 22">
+<div *ngIf="panelId == 23">
 <p>A Cdk9-PP1 switch for RNA polymerase II elongation-termination.</p>
 
 
@@ -178,7 +186,7 @@
 <p>Originally published in <a href='https://www.nature.com/articles/s41586-018-0214-z'>Nature</a>.</p>
 
 </div>
-<div *ngIf="panelId == 23">
+<div *ngIf="panelId == 24">
 <p>Quantitative phosphoproteomics reveals the signaling dynamics of cell-cycle kinases; ~10K phosphorylation sites now in PomBase.</p>
 
 
@@ -186,7 +194,7 @@
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30946-X'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 24">
+<div *ngIf="panelId == 25">
 <p>Sharpening the anaphase switch.</p>
 
 
@@ -194,7 +202,7 @@
 <p>Originally published in <a href='https://linkinghub.elsevier.com/retrieve/pii/S2211-1247(17)30069-4'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 25">
+<div *ngIf="panelId == 26">
 <p>Microtubule depolymerization in scd1Δ cells leads to PORTLI growth.</p>
 
 
@@ -202,7 +210,7 @@
 <p>Originally published in the <a href='http://jcs.biologists.org/content/131/14/jcs216580'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 26">
+<div *ngIf="panelId == 27">
 <p>Essential genes for quiescence to cell cycle switching.</p>
 
 
@@ -210,7 +218,7 @@
 <p>Originally published in <a href='http://advances.sciencemag.org/content/4/8/eaat5685'>Science Advances</a>.</p>
 
 </div>
-<div *ngIf="panelId == 27">
+<div *ngIf="panelId == 28">
 <p>Genome-wide phenotypic analysis of chromate toxicity.</p>
 
 
@@ -218,7 +226,7 @@
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007595'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 28">
+<div *ngIf="panelId == 29">
 <p><em>wtf</em> genes in poison–antidote meiotic drive and its suppression.</p>
 
 
@@ -226,7 +234,7 @@
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007836'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 29">
+<div *ngIf="panelId == 30">
 <p>RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not.</p>
 
 
@@ -234,7 +242,7 @@
 <p>Originally published in <a href='https://elifesciences.org/articles/40670'>eLife</a>. Image from <a href="https://elifesciences.org/articles/40670#fig7">eLife 2019;8:e40670</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 30">
+<div *ngIf="panelId == 31">
 <p>Cryo-EM structure of kinesin-5-microtubule complex reveals a distinct binding footprint and mechanism of drug resistance.</p>
 
 
@@ -242,7 +250,7 @@
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S0022283619300105'>JMB</a>.</p>
 
 </div>
-<div *ngIf="panelId == 31">
+<div *ngIf="panelId == 32">
 <p>Centromere DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle.</p>
 
 
@@ -250,7 +258,7 @@
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S0960982218314167'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 32">
+<div *ngIf="panelId == 33">
 <p>DNA topoisomerase II phosphorylation in fission yeast reveals anticancer mechanism.</p>
 
 
@@ -258,7 +266,7 @@
 <p>Originally published in <a href='http://www.jbc.org/content/early/2019/01/11/jbc.RA118.004955.long'>Journal of Biological Chemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 33">
+<div *ngIf="panelId == 34">
 <p>Zinc transporters belonging to the Cation Diffusion Facilitator (CDF) family have complementary roles in transporting zinc out of the cytosol.</p>
 
 
@@ -266,7 +274,7 @@
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007262'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 34">
+<div *ngIf="panelId == 35">
 <p>Systematic analysis reveals the prevalence and principles of bypassable gene essentiality.</p>
 
 
@@ -274,7 +282,7 @@
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-019-08928-1'>Nature Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 35">
+<div *ngIf="panelId == 36">
 <p>Swi5-Sfr1 stimulates Rad51 recombinase filament assembly by modulating Rad51 dissociation.</p>
 
 
@@ -282,7 +290,7 @@
 <p>Originally published in <a href='https://www.pnas.org/content/115/43/E10059.long'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 36">
+<div *ngIf="panelId == 37">
 <p>Specific primary septum detection reveals septum and cleavage furrow ingression during early anaphase independent of mitosis completion.</p>
 
 
@@ -290,7 +298,7 @@
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007388'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 37">
+<div *ngIf="panelId == 38">
 <p>Paxillin-mediated recruitment of calcineurin to the contractile ring is required for cytokinesis.</p>
 
 
@@ -298,127 +306,127 @@
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S2211124718315079?via%3Dihub'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 38">
+<div *ngIf="panelId == 39">
 <p>Taf12 phosphorylation inhibits sexual differentiation downstream of TORC2.</p>
 
 <p>Originally published in <a href='http://embor.embopress.org/content/18/12/2197.long'>EMBO reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 39">
+<div *ngIf="panelId == 40">
 <p>Unexpected insertion of carrier DNA during CRISPR-Cas9, and “unknowns” remain “unknown”</p>
 
 <p>Originally published in <a href='https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-019-4228-x'>BMC Research Notes</a>.</p>
 
 </div>
-<div *ngIf="panelId == 40">
+<div *ngIf="panelId == 41">
 <p>NDR Kinase Sid2 Drives Anillin-like Mid1 from the Membrane to Promote Cytokinesis.</p>
 
 <p>Originally published in <a href='https://www.cell.com/current-biology/fulltext/S0960-9822(19)30134-4'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 41">
+<div *ngIf="panelId == 42">
 <p>Set7, a histone methyltransferase for the uncharted histone H3-37 mark.</p>
 
 <p>Originally published in <a href='https://www.cell.com/structure/fulltext/S0969-2126(19)30011-5'>Structure</a>.</p>
 
 </div>
-<div *ngIf="panelId == 42">
+<div *ngIf="panelId == 43">
 <p>Fission yeast contains separate CC- and A-adding tRNA nucleotidyltransferases.</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S0006291X18325634'>Biochemical and Biophysical Research Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 43">
+<div *ngIf="panelId == 44">
 <p>Distinct roles of myosin-II isoforms in cytokinesis under normal and stressed conditions.</p>
 
 <p>Originally published in <a href='https://doi.org/10.1016/j.isci.2019.03.014'>iScience</a>.</p>
 
 </div>
-<div *ngIf="panelId == 44">
+<div *ngIf="panelId == 45">
 <p>Previously uncharacterized protein, Ync13, has a role during late stages of cytokinesis.</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/full/10.1091/mbc.E18-04-0225'>Molecular Biology of the Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 45">
+<div *ngIf="panelId == 46">
 <p>Simple procedure for the generation of temperature-sensitive mutations with error-prone PCR.</p>
 
 <p>Originally published in <a href='https://www.tandfonline.com/doi/abs/10.1080/09168451.2019.1611414'>Bioscience, Biotechnology, and Biochemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 46">
+<div *ngIf="panelId == 47">
 <p>Isolation of single amino acid t-s mutants in condensin hinge domain.</p>
 
 <p>Originally published in <a href='https://www.g3journal.org/content/9/5/1777.long'>G3: Genes, Genomes, Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 47">
+<div *ngIf="panelId == 48">
 <p>Suppressor screening reveals common kleisin-hinge interaction in condensin and cohesin.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/content/early/2019/05/09/1902699116.long'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 48">
+<div *ngIf="panelId == 49">
 <p>Sequencing of suppressor DNA mixtures identifies pathways that compensate for chromosome segregation defects.</p>
 
 <p>Originally published in <a href='http://www.g3journal.org/cgi/pmidlookup?view=long&amp;pmid=29352077'>G3: Genes, Genomes, Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 49">
+<div *ngIf="panelId == 50">
 <p>A. Prevailing ring model vs. B. hold and release model; Suppressor mutation analysis combined with 3D modeling proposes a different mechanism for cohesin.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/content/115/21/E4833.long'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 50">
+<div *ngIf="panelId == 51">
 <p>Fission yeast TRP channel Pkd2p localizes to the cleavage furrow during cytokinesis.</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/abs/10.1091/mbc.E18-04-0270'>Molecular Biology of the Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 51">
+<div *ngIf="panelId == 52">
 <p>The J-domain co-chaperone Rsp1 interacts with Mto1 to organize non-centrosomal microtubule assembly.</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/10.1091/mbc.E18-05-0279'>Molecular Biology of the Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 52">
+<div *ngIf="panelId == 53">
 <p>The PCNA unloader Elg1 promotes recombination at collapsed replication forks.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/47277'>eLife</a>. Image from <a href="https://elifesciences.org/articles/47277#fig7">eLife 2019;8:e47277</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 53">
+<div *ngIf="panelId == 54">
 <p>MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly.</p>
 
 <p>Originally published in <a href='https://www.g3journal.org/content/9/1/269.long'>G3: Genes, Genomes, Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 54">
+<div *ngIf="panelId == 55">
 <p>Nuclear “blebbing” in Lem2 mutants from “Nuclear membrane protein Lem2 regulates nuclear size through membrane flow”.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-019-09623-x'>Nature Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 55">
+<div *ngIf="panelId == 56">
 <p>Coordinated Roles of the Putative Ceramide-Conjugation Protein, Cwh43, and a Mn 2+ -Transporting, P-Type ATPase, Pmr1.</p>
 
 <p>Originally published in <a href='https://www.g3journal.org/content/early/2019/06/14/g3.119.400281.long'>G3: Genes, Genomes, Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 56">
+<div *ngIf="panelId == 57">
 <p>Epe1 associates with the SAGA complex to promote transcription of repeats for heterochromatin assembly.</p>
 
 <p>Originally published in <a href='http://genesdev.cshlp.org/content/33/1-2/116.long'>Genes &amp; Development</a>.</p>
 
 </div>
-<div *ngIf="panelId == 57">
+<div *ngIf="panelId == 58">
 <p>The F-BAR Domain of Rga7 Relies on a Cooperative Mechanism of Membrane Binding with Rng10.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30149-4'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 58">
+<div *ngIf="panelId == 59">
 <p>The fitness landscape of the fission yeast genome.</p>
 
 
@@ -430,337 +438,337 @@
 <p><a href='/jbrowse/?tracks=DNA%20sequence%2CPomBase%20forward%20strand%20features%2CPomBase%20reverse%20strand%20features%2CConservation%20of%20sites%20over%20the%20phylogeny%20of%20S.%20pombe%E2%80%9A%20S.%20octosporus%E2%80%9A%20S.%20japonicus%E2%80%9A%20and%20S.%20cryophilus%20(higher%20values%20are%20associated%20with%20higher%20degree%20of%20conservation)-%20Grech%20et%20al.%20(2019)%2CHDE%20units%E2%80%9A%20continuous%20runs%20of%20states%20S1-S3%20-%20Grech%20et%20al.%20(2019)%2CTransposon%20insertion%20sites%20-%20Grech%20et%20al.%20(2019)%2CTransposon%20insertion%20sites%20smoothed%20to%20states%20S1-S5%20(lower%20states%20have%20fewer%20insertions)%20-%20Grech%20et%20al.%20(2019)&amp;loc=III%3A804712..899614&amp;highlight='>View datasets in the genome browser …</a></p>
 
 </div>
-<div *ngIf="panelId == 59">
+<div *ngIf="panelId == 60">
 <p>A Cdc42 GEF, Gef1, organizes F-BAR Cdc15 along the actomyosin ring.</p>
 
 <p>Originally published in <a href='https://jcs.biologists.org/content/132/5/jcs223776.long'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 60">
+<div *ngIf="panelId == 61">
 <p>Abrogation of glucosidase I-mediated glycoprotein deglucosylation results in a sick phenotype in fission yeasts: Model for the human MOGS-CDG disorder.</p>
 
 <p>Originally published in <a href='http://www.jbc.org/content/293/52/19957.long'>Journal of Biological Chemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 61">
+<div *ngIf="panelId == 62">
 <p>Factors affecting template switch recombination associated with restarted DNA replication.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/41697'>eLife</a>. Image from <a href="https://elifesciences.org/articles/41697#fig7">eLife 2019;8:e41697</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 62">
+<div *ngIf="panelId == 63">
 <p>Asc1 stabilizes the interaction between eIF3a and Rps0A/uS2 for protein synthesis.</p>
 
 <p>Originally published in <a href='https://mcb.asm.org/content/early/2019/07/03/MCB.00161-19.long'>Molecular and Cellular Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 63">
+<div *ngIf="panelId == 64">
 <p>H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly.</p>
 
 <p>Originally published in <a href='https://www.embopress.org/doi/full/10.15252/embr.201948111'>EMBO reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 64">
+<div *ngIf="panelId == 65">
 <p>Lem2 is retained at the nuclear envelope through its interaction with Bqt4 in fission yeast. LEM domain directly binds to DNA.</p>
 
 <p>Originally published in <a href='https://onlinelibrary.wiley.com/doi/full/10.1111/gtc.12557'>Genes Cells</a>.</p>
 
 </div>
-<div *ngIf="panelId == 65">
+<div *ngIf="panelId == 66">
 <p>A new TF binding site (Loz1 response element) for zinc repression.</p>
 
 <p>Originally published in <a href='https://onlinelibrary.wiley.com/doi/abs/10.1111/mmi.14384'>Molecular Microbiology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 66">
+<div *ngIf="panelId == 67">
 <p>Kinetochore-mediated outward force promotes spindle pole separation.</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/10.1091/mbc.E19-07-0366'>Molecular Biology of the Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 67">
+<div *ngIf="panelId == 68">
 <p>Capping Protein Insulates Arp2/3-Assembled Actin Patches from Formins.</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S0960982219310127'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 68">
+<div *ngIf="panelId == 69">
 <p>Microtubules and Alp7-Alp14 (TACC-TOG) reposition meiotic chromosomes.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/ncb2782'>Nature Cell Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 69">
+<div *ngIf="panelId == 70">
 <p>F-BAR Cdc15 Promotes Cdc42 Activation During Cytokinesis and Cell Polarization in <em>Schizosaccharomyces pombe</em>.</p>
 
 <p>Originally published in <a href='https://www.genetics.org/content/early/2019/10/07/genetics.119.302649.long'>Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 70">
+<div *ngIf="panelId == 71">
 <p>Tel2-Tti1-Tti2 complex destabilization eliminates Rad3-ATR kinase signaling in the DNA replication checkpoint and leads to telomere shortening.</p>
 
 <p>Originally published in <a href='https://mcb.asm.org/content/39/20/e00175-19'>Molecular and Cell Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 71">
+<div *ngIf="panelId == 72">
 <p>CLASP promotes microtubule bundling in metaphase spindle independently of Ase1.</p>
 
 <p>Originally published in <a href='https://bio.biologists.org/content/8/10/bio045716'>Biology Open</a>.</p>
 
 </div>
-<div *ngIf="panelId == 72">
+<div *ngIf="panelId == 73">
 <p>The Bub1-TPR domain interacts directly with Mad3 to generate robust spindle checkpoint arrest.</p>
 
 <p>Originally published in <a href='https://www.cell.com/current-biology/fulltext/S0960-9822(19)30704-3'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 73">
+<div *ngIf="panelId == 74">
 <p>Effects of the microtubule nucleator Mto1 on chromosome movement, DNA repair and sister chromatid cohesion.</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/10.1091/mbc.E19-05-0301'>Molecular Biology of the Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 74">
+<div *ngIf="panelId == 75">
 <p>Association of mitochondria with microtubules inhibits mitochondrial fission.</p>
 
 <p>Originally published in <a href='http://www.jbc.org/content/294/10/3385'>Journal of Biological Chemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 75">
+<div *ngIf="panelId == 76">
 <p>A highly modular toolbox to introduce heterologous sequences and includes antibiotic resistance markers, promoters, fluorescent tags, and terminators.</p>
 
 <p>Originally published in <a href='https://jcs.biologists.org/content/early/2019/11/29/jcs.240754.long'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 76">
+<div *ngIf="panelId == 77">
 <p>Role for cleavage and polyadenylation factor (CPF) in RNAi-independent heterochromatin domain assembly.</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S2211124719307545?via%3Dihub'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 77">
+<div *ngIf="panelId == 78">
 <p>Gcn5-mediated acetylation at MBF-regulated promoters induces the G1/S transcriptional wave.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/47/16/8439/5526704'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 78">
+<div *ngIf="panelId == 79">
 <p>Mkt1 is required for RNAi-mediated silencing and establishment of heterochromatin in fission yeast.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz1157/5673137'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 79">
+<div *ngIf="panelId == 80">
 <p>Physical basis for long-distance communication along meiotic chromosomes.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/content/115/40/E9333.long'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 80">
+<div *ngIf="panelId == 81">
 <p>A novel interplay between GEFs orchestrates Cdc42 activity during cell polarity and cytokinesis in fission yeast.</p>
 
 <p>Originally published in <a href='https://jcs.biologists.org/content/132/23/jcs236018.long'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 81">
+<div *ngIf="panelId == 82">
 <p>Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30036-1'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 82">
+<div *ngIf="panelId == 83">
 <p>Structures of the Mitochondrial CDP-DAG Synthase Tam41 Suggest a Potential Lipid Substrate Pathway from Membrane to the Active Site.</p>
 
 <p>Originally published in <a href='https://www.cell.com/structure/fulltext/S0969-2126(19)30162-5'>Structure</a>.</p>
 
 </div>
-<div *ngIf="panelId == 83">
+<div *ngIf="panelId == 84">
 <p>Atg38-Atg8 Interaction in Fission Yeast Establishes a Positive Feedback Loop to Promote Autophagy</p>
 
 <p>Originally published in <a href='https://www.tandfonline.com/doi/full/10.1080/15548627.2020.1713644'>Autophagy</a>.</p>
 
 </div>
-<div *ngIf="panelId == 84">
+<div *ngIf="panelId == 85">
 <p>Plasma Membrane Furrows Control Plasticity of ER-PM Contacts.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31763-2'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 85">
+<div *ngIf="panelId == 86">
 <p>Chromatin remodeler Fft3 plays a dual role at blocked DNA replication forks.</p>
 
 <p>Originally published in <a href="https://www.life-science-alliance.org/content/2/5/e201900433">Life Science Alliance</a>.</p>
 
 </div>
-<div *ngIf="panelId == 86">
+<div *ngIf="panelId == 87">
 <p>Cortical tethering of mitochondria by the anchor protein Mcp5 enables uniparental inheritance.</p>
 
 <p>Originally published in <a href='https://rupress.org/jcb/article-lookup/doi/10.1083/jcb.201901108'>Journal of Cell Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 87">
+<div *ngIf="panelId == 88">
 <p>Casein kinase 2 regulates telomere protein complex formation through Rap1 phosphorylation.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/47/13/6871/5498753'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 88">
+<div *ngIf="panelId == 89">
 <p>Checkpoint Regulation of Nuclear Tos4 Defines S Phase Arrest in Fission Yeast.</p>
 
 <p>Originally published in <a href='https://www.g3journal.org/content/10/1/255'>G3: Genes, Genomes, Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 89">
+<div *ngIf="panelId == 90">
 <p>The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning.</p>
 
 <p>Originally published in <a href='https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-019-0271-z'>Epigenetics &amp; Chromatin</a>.</p>
 
 </div>
-<div *ngIf="panelId == 90">
+<div *ngIf="panelId == 91">
 <p>Dramatically diverse ’Schizosaccharomyces pombe wtf* meiotic drivers all display high gamete-killing efficiency.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008350'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 91">
+<div *ngIf="panelId == 92">
 <p>Genetic investigation of formaldehyde-induced DNA damage response in <em>Schizosaccharomyces pombe</em>.</p>
 
 <p>Originally published in <a href='https://link.springer.com/article/10.1007%2Fs00294-020-01057-z'>Current Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 92">
+<div *ngIf="panelId == 93">
 <p>Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.</p>
 
 <p>Originally published in <a href='https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13068'>Aging Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 93">
+<div *ngIf="panelId == 94">
 <p>Cooperative interactions facilitate stimulation of Rad51 by the Swi5-Sfr1 auxiliary factor complex.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/52566'>eLife</a>. Image: left panel from <a href="https://elifesciences.org/articles/52566#fig7">eLife 2020;9:52566</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms; right panel B. Argunhan pers. comm.</p>
 
 </div>
-<div *ngIf="panelId == 94">
+<div *ngIf="panelId == 95">
 <p>Chaperone-Facilitated Aggregation of Thermo-Sensitive Proteins Shields Them from Degradation during Heat Stress.</p>
 
 <p>Originally published in <a href="http://dx.doi.org/10.1016/j.celrep.2020.01.077">Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 95">
+<div *ngIf="panelId == 96">
 <p>Ctp1 protein-DNA filaments promote DNA bridging and DNA double-strand break repair.</p>
 
 <p>Originally published in <a href="https://www.jbc.org/content/294/9/3312">Journal of Biological Chemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 96">
+<div *ngIf="panelId == 97">
 <p>Chromosome-associated RNA-protein complexes promote pairing of homologous chromosomes during meiosis.</p>
 
 <p>Originally published in <a href="https://www.nature.com/articles/s41467-019-13609-0">Nature Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 97">
+<div *ngIf="panelId == 98">
 <p>Mutations in a single signaling pathway allow cell growth in heavy water.</p>
 
 <p>Image reprinted with permission from <a href='https://pubs.acs.org/doi/full/10.1021/acssynbio.9b00376'>ACS Synthetic Biology 2020 9 (4), 733-748</a>. Copyright 2020 American Chemical Society.</p>
 
 </div>
-<div *ngIf="panelId == 98">
+<div *ngIf="panelId == 99">
 <p>Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance.</p>
 
 <p>Originally published in <a href='https://www.embopress.org/doi/full/10.15252/msb.20199270'>Molecular Systems Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 99">
+<div *ngIf="panelId == 100">
 <p>Conserved roles of chromatin remodellers in cohesin loading onto chromatin.</p>
 
 <p>Originally published in <a href='https://link.springer.com/article/10.1007%2Fs00294-020-01075-x'>Current Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 100">
+<div *ngIf="panelId == 101">
 <p>Different Functionality of Cdc20 Binding Sites within the Mitotic Checkpoint Complex.</p>
 
 <p>Originally published in <a href='https://doi.org/10.1016/j.cub.2017.03.007'>Curr.Biol.</a></p>
 
 </div>
-<div *ngIf="panelId == 101">
+<div *ngIf="panelId == 102">
 <p>Active replication checkpoint drives genome instability in fission yeast mcm4 mutant.</p>
 
 <p>Originally published in <a href='https://mcb.asm.org/content/early/2020/04/21/MCB.00033-20'>Molecular and Cellular Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 102">
+<div *ngIf="panelId == 103">
 <p>Spt5 phosphorylation and the Rtf1 Plus3 domain promote Rtf1 function through distinct mechanisms.</p>
 
 <p>Originally published in <a href='https://mcb.asm.org/content/early/2020/05/01/MCB.00150-20'>Molecular and Cellular Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 103">
+<div *ngIf="panelId == 104">
 <p>Glucose limitation and pka1 deletion rescue aberrant mitotic spindle formation induced by Mal3 overexpression in Schizosaccharomyces pombe.</p>
 
 <p>Originally published in <a href='https://www.tandfonline.com/doi/full/10.1080/09168451.2020.1763157'>Bioscience, Biotechnology, and Biochemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 104">
+<div *ngIf="panelId == 105">
 <p>Two Auxiliary Factors Promote Dmc1-driven DNA Strand Exchange via Stepwise Mechanisms .</p>
 
 <p>Originally published in <a href='https://www.pnas.org/content/117/22/12062'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 105">
+<div *ngIf="panelId == 106">
 <p>DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division.</p>
 
 <p>Originally published in <a href='https://doi.org/10.1091/mbc.E20-01-0026'>Molecular Biology of the Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 106">
+<div *ngIf="panelId == 107">
 <p>Nutrient-dependent control of RNA polymerase II elongation rate regulates specific gene expression programs by alternative polyadenylation.</p>
 
 <p>Originally published in <a href='http://genesdev.cshlp.org/content/early/2020/06/03/gad.337212.120'>Genes &amp; Development</a>.</p>
 
 </div>
-<div *ngIf="panelId == 107">
+<div *ngIf="panelId == 108">
 <p>DNA replication machinery prevents Rad52-dependent single-strand annealing that leads to gross chromosomal rearrangements at centromeres.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s42003-020-0934-0'>Communications Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 108">
+<div *ngIf="panelId == 109">
 <p>Nuclear Envelope Attachment of Telomeres Limits TERRA and Telomeric Rearrangements in Quiescent Fission Yeast Cells.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/48/6/3029/5715813'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 109">
+<div *ngIf="panelId == 110">
 <p>Cdk9 and H2Bub1 signal to Clr6-CII/Rpd3S to suppress aberrant antisense transcription.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/48/13/7154/5851387'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 110">
+<div *ngIf="panelId == 111">
 <p>The phosphatase inhibitor Sds23 regulates cell division symmetry in fission yeast.</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/full/10.1091/mbc.E19-05-0254'>Molecular Biology of the Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 111">
+<div *ngIf="panelId == 112">
 <p>A role of the Nse4 kleisin and Nse1/Nse3 KITE subunits in the ATPase cycle of SMC5/6.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41598-020-66647-w'>Scientific Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 112">
+<div *ngIf="panelId == 113">
 <p>Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition.</p>
 
 <p>Originally published in <a href='https://rupress.org/jcb/article/219/6/e202001147/151694/Sterol-biosensor-reveals-LAM-family-Ltc1-dependent'>Journal of Cell Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 113">
+<div *ngIf="panelId == 114">
 <p>A UPR-Induced Soluble ER-Phagy Receptor Acts with VAPs to Confer ER Stress Resistance.</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/abs/pii/S1097276520305104?via%3Dihub'>Molecular Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 114">
+<div *ngIf="panelId == 115">
 <p>CRL4Cdt2 ubiquitin ligase regulates Dna2 and Rad16 (XPF) nucleases by targeting Pxd1 for degradation.</p>
 
 
@@ -768,859 +776,859 @@
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008933'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 115">
+<div *ngIf="panelId == 116">
 <p>Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation.</p>
 
 <p>Originally published in <a href="http://dx.doi.org/10.1016/j.celrep.2020.01.094">Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 116">
+<div *ngIf="panelId == 117">
 <p>Closed mitosis requires local disassembly of the nuclear envelope.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41586-020-2648-3'>Nature</a>.</p>
 
 </div>
-<div *ngIf="panelId == 117">
+<div *ngIf="panelId == 118">
 <p>Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant.</p>
 
 <p>Originally published in <a href='http://dx.doi.org/10.1016/j.isci.2019.100809'>iScience</a>.</p>
 
 </div>
-<div *ngIf="panelId == 118">
+<div *ngIf="panelId == 119">
 <p>Atypical meiosis can be adaptive in outcrossed Schizosaccharomyces pombe due to wtf meiotic drivers.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/57936'>eLife</a>. Image from <a href="https://elifesciences.org/articles/57936#fig7">eLife 2020;9:e57936</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 119">
+<div *ngIf="panelId == 120">
 <p>Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-020-15060-y'>Nature Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 120">
+<div *ngIf="panelId == 121">
 <p>Condensin locates at transcriptional termination sites in mitosis, possibly releasing mitotic transcripts.</p>
 
 <p>Originally published in <a href='https://royalsocietypublishing.org/doi/10.1098/rsob.190125'>Open Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 121">
+<div *ngIf="panelId == 122">
 <p>Atg1 kinase in fission yeast is activated by Atg11-mediated dimerization and cis-autophosphorylation.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/58073'>eLife</a>. Image from <a href="https://elifesciences.org/articles/58073#fig4">eLife 2020;9:e58073</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 122">
+<div *ngIf="panelId == 123">
 <p>The Catalytic-Dependent and -Independent Roles of Lsd1 and Lsd2 Lysine Demethylases in Heterochromatin Formation in <em>Schizosaccharomyces pombe</em>.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/2073-4409/9/4/955'>Cells</a>.</p>
 
 </div>
-<div *ngIf="panelId == 123">
+<div *ngIf="panelId == 124">
 <p>Removal of centrosomal PP1 by NIMA kinase unlocks the MPF feedback loop to promote mitotic commitment in S. pombe.</p>
 
 <p>Originally published in <a href='https://www.cell.com/current-biology/fulltext/S0960-9822(12)01512-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982212015126%3Fshowall%3Dtrue'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 124">
+<div *ngIf="panelId == 125">
 <p>Requirement of PP2A-B56 Par1 for the Stabilization of the CDK Inhibitor Rum1 and Activation of APC/C Ste9 during Pre-Start G1 in S. pombe.</p>
 
 <p>Originally published in <a href='https://www.cell.com/iscience/fulltext/S2589-0042(20)30248-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004220302480%3Fshowall%3Dtrue'>iScience</a>.</p>
 
 </div>
-<div *ngIf="panelId == 125">
+<div *ngIf="panelId == 126">
 <p>A Redox-Sensitive Thiol in Wis1 Modulates the Fission Yeast Mitogen-Activated Protein Kinase Response to H2O2 and Is the Target of a Small Molecule.</p>
 
 <p>Originally published in <a href='https://mcb.asm.org/content/40/7/e00346-19'>Molecular and Cellular Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 126">
+<div *ngIf="panelId == 127">
 <p>RNA-Binding Protein Rnc1 Regulates Cell Length at Division and Acute Stress Response in Fission Yeast through Negative Feedback Modulation of the Stress-Activated Mitogen-Activated Protein Kinase Pathway.</p>
 
 <p>Originally published in <a href='https://mbio.asm.org/content/11/1/e02815-19'>mBio</a>.</p>
 
 </div>
-<div *ngIf="panelId == 127">
+<div *ngIf="panelId == 128">
 <p>Golgi localization of glycosyltransferases requires Gpp74p in Schizosaccharomyces pombe.</p>
 
 <p>Originally published in <a href='https://link.springer.com/article/10.1007/s00253-020-10881-9'>Applied Microbiology and Biotechnology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 128">
+<div *ngIf="panelId == 129">
 <p>Stress-activated MAPK signalling controls fission yeast actomyosin ring integrity by modulating formin For3 levels.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/57951'>eLife</a>. Image from <a href="https://elifesciences.org/articles/58073#fig5">eLife 2020;9:e57951</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 129">
+<div *ngIf="panelId == 130">
 <p>The CDK Pef1 and PP4 (Ppe2) oppose each other for regulating cohesin binding to chromosomes.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/50556'>eLife</a>. Image from <a href="https://elifesciences.org/articles/50556#fig8">eLife 2020;9:e50556</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 130">
+<div *ngIf="panelId == 131">
 <p>A review of genes involved in extension of chronological lifespan, and the identification of 4 new CLS genes.</p>
 
 <p>Originally published in <a href='https://onlinelibrary.wiley.com/doi/10.1111/mmi.14627'>Molecular Microbiology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 131">
+<div *ngIf="panelId == 132">
 <p>Fission yeast condensin contributes to interphase chromatin organization and prevents transcription-coupled DNA damage.</p>
 
 <p>Originally published in <a href='https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02183-0'>Genome Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 132">
+<div *ngIf="panelId == 133">
 <p>Elongation/Termination Factor Exchange Mediated by PP1 Phosphatase Orchestrates Transcription Termination.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31422-0'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 133">
+<div *ngIf="panelId == 134">
 <p>Molecular Mechanism for the Actin-Binding Domain of α-Actinin Ain1 Elucidated by Molecular Dynamics Simulations and Mutagenesis Experiments.</p>
 
 <p>Originally published in <a href='https://pubs.acs.org/doi/full/10.1021/acs.jpcb.0c04623'>The Journal of Physical Chemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 134">
+<div *ngIf="panelId == 135">
 <p>The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-020-19516-z'>Nature Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 135">
+<div *ngIf="panelId == 136">
 <p>Selective Nuclear Pore Complex Removal Drives Nuclear Envelope Division in Fission Yeast.</p>
 
 <p>Originally published in <a href='https://linkinghub.elsevier.com/retrieve/pii/S0960982220307533'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 136">
+<div *ngIf="panelId == 137">
 <p>High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/1422-0067/21/23/9022/htm'>International Journal of Molecular Sciences</a>.</p>
 
 </div>
-<div *ngIf="panelId == 137">
+<div *ngIf="panelId == 138">
 <p>Mitochondrial respiration is required to provide amino acids during fermentative proliferation of fission yeast.</p>
 
 <p>Originally published in <a href='https://www.embopress.org/doi/full/10.15252/embr.202050845'>EMBO Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 138">
+<div *ngIf="panelId == 139">
 <p>Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast.</p>
 
 <p>Originally published in <a href='http://www.biomolther.org/journal/view.html?uid=1272&vmd=Full'>Biomolecules &amp; Therapeutics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 139">
+<div *ngIf="panelId == 140">
 <p>Serine catabolism produces ROS, sensitizes cells to actin dysfunction, and suppresses cell growth in fission yeast.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41429-020-0305-6'>The Journal of Antibiotics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 140">
+<div *ngIf="panelId == 141">
 <p>Phosphoproteomics Reveals Novel Targets and Phosphoprotein Networks in Cell Cycle Mediated by Dsk1.</p>
 
 <p>Originally published in <a href='https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00027'>Journal of Proteome Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 141">
+<div *ngIf="panelId == 142">
 <p>Opposite Surfaces of the Cdc15 F-BAR Domain Create a Membrane Platform That Coordinates Cytoskeletal and Signaling Components for Cytokinesis.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31515-1'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 142">
+<div *ngIf="panelId == 143">
 <p>Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/61245'>eLife</a>. Image from <a href="https://elifesciences.org/articles/61245#fig7">eLife 2020;9:e61245</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 143">
+<div *ngIf="panelId == 144">
 <p>The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009183'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 144">
+<div *ngIf="panelId == 145">
 <p>The Fission Yeast RNA-Binding Protein Meu5 Is Involved in Outer Forespore Membrane Breakdown during Spore Formation.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/2309-608X/6/4/284'>Journal of Fungi</a>.</p>
 
 </div>
-<div *ngIf="panelId == 145">
+<div *ngIf="panelId == 146">
 <p>Formation of S. pombe Erh1 homodimer mediates gametogenic gene silencing and meiosis progression.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41598-020-57872-4'>Scientific Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 146">
+<div *ngIf="panelId == 147">
 <p>Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008893'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 147">
+<div *ngIf="panelId == 148">
 <p>The Hsp40 Mas5 Connects Protein Quality Control and the General Stress Response through the Thermo-sensitive Pyp1.</p>
 
 <p>Originally published in <a href='https://linkinghub.elsevier.com/retrieve/pii/S2589-0042(20)30922-6'>iScience</a>.</p>
 
 </div>
-<div *ngIf="panelId == 148">
+<div *ngIf="panelId == 149">
 <p>The fission yeast Pin1 peptidyl-prolyl isomerase promotes dissociation of Sty1 MAPK from RNA polymerase II and recruits Ssu72 phosphatase to facilitate oxidative stress induced transcription.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/49/2/805/6067400'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 149">
+<div *ngIf="panelId == 150">
 <p>Multiplexed proteome profiling of carbon source perturbations in two yeast species with SL-SP3-TMT..</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S1874391919303033'>Journal of Proteomics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 150">
+<div *ngIf="panelId == 151">
 <p>Comparison of loop extrusion and diffusion capture as mitotic chromosome formation pathways in fission yeast.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa1270/6090303'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 151">
+<div *ngIf="panelId == 152">
 <p>Escape from mitotic catastrophe by actin-dependent nuclear displacement in fission yeast..</p>
 
 <p>Originally published in <a href='https://www.cell.com/iscience/fulltext/S2589-0042(20)31228-1'>iScience</a>.</p>
 
 </div>
-<div *ngIf="panelId == 152">
+<div *ngIf="panelId == 153">
 <p>RNA interference is essential for cellular quiescence.</p>
 
 <p>Originally published in <a href='https://science.sciencemag.org/content/354/6313/aah5651.long'>Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 153">
+<div *ngIf="panelId == 154">
 <p>Integrity of a heterochromatic domain ensured by its boundary elements.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/content/117/35/21504'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 154">
+<div *ngIf="panelId == 155">
 <p>Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast..</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/49/1/383/6031432'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 155">
+<div *ngIf="panelId == 156">
 <p>Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41598-020-63209-y'>Scientific Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 156">
+<div *ngIf="panelId == 157">
 <p>Repression of a large number of genes requires interplay between homologous recombination and HIRA.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab027/6123375'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 157">
+<div *ngIf="panelId == 158">
 <p>The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis.</p>
 
 <p>Originally published in <a href='https://doi.org/10.1016/j.cub.2019.12.053'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 158">
+<div *ngIf="panelId == 159">
 <p>Replication dynamics of recombination-dependent replication forks.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-021-21198-0'>Nature Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 159">
+<div *ngIf="panelId == 160">
 <p>TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41556-021-00631-y'>Nature Cell Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 160">
+<div *ngIf="panelId == 161">
 <p>Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex.</p>
 
 <p>Originally published in <a href='https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-021-00382-y'>Epigenetics &amp; Chromatin</a>.</p>
 
 </div>
-<div *ngIf="panelId == 161">
+<div *ngIf="panelId == 162">
 <p>Differential GAP requirement for Cdc42-GTP polarization during proliferation and sexual reproduction..</p>
 
 <p>Originally published in <a href='https://rupress.org/jcb/article/217/12/4215/120308/Differential-GAP-requirement-for-Cdc42-GTP'>Journal of Cell Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 162">
+<div *ngIf="panelId == 163">
 <p>Size-Dependent Increase in RNA Polymerase II Initiation Rates Mediates Gene Expression Scaling with Cell Size.</p>
 
 <p>Originally published in <a href='https://www.cell.com/current-biology/fulltext/S0960-9822(20)30097-X'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 163">
+<div *ngIf="panelId == 164">
 <p>Schizosaccharomyces pombe KAT5 contributes to resection and repair of a DNA double strand break.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyab042/6173406'>Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 164">
+<div *ngIf="panelId == 165">
 <p>Epigenetic gene silencing by heterochromatin primes fungal resistance.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41586-020-2706-x'>Nature</a>.</p>
 
 </div>
-<div *ngIf="panelId == 165">
+<div *ngIf="panelId == 166">
 <p>Identification and structural analysis of the Schizosaccharomyces pombe SMN complex.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab158/6179931'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 166">
+<div *ngIf="panelId == 167">
 <p>The Role of Non-Catalytic Domains of Hrp3 in Nucleosome Remodeling.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/1422-0067/22/4/1793'>International Journal of Molecular Sciences</a>.</p>
 
 </div>
-<div *ngIf="panelId == 167">
+<div *ngIf="panelId == 168">
 <p>Analysis of the SNARE Stx8 recycling reveals that the retromer-sorting motif has undergone evolutionary divergence.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009463'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 168">
+<div *ngIf="panelId == 169">
 <p>TOR Complex 2- independent mutations in the regulatory PIF pocket of Gad8AKT1/SGK1 define separate branches of the stress response mechanisms in fission yeast.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009196'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 169">
+<div *ngIf="panelId == 170">
 <p>Emr1 regulates the number of foci of the endoplasmic reticulum-mitochondria encounter structure complex.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-020-20866-x'>Nature Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 170">
+<div *ngIf="panelId == 171">
 <p>Multiple nutritional phenotypes of fission yeast mutants defective in genes encoding essential mitochondrial proteins.</p>
 
 <p>Originally published in <a href='https://royalsocietypublishing.org/doi/10.1098/rsob.200369'>Open Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 171">
+<div *ngIf="panelId == 172">
 <p>Acute Heat Stress Leads to Reversible Aggregation of Nuclear Proteins into Nucleolar Rings in Fission Yeast.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31366-8'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 172">
+<div *ngIf="panelId == 173">
 <p>RNA polymerase backtracking results in the accumulation of fission yeast condensin at active genes.</p>
 
 <p>Originally published in <a href='https://www.life-science-alliance.org/content/4/6/e202101046'>Life Science Alliance</a>.</p>
 
 </div>
-<div *ngIf="panelId == 173">
+<div *ngIf="panelId == 174">
 <p>Meikin synergizes with shugoshin to protect cohesin Rec8 during meiosis I.</p>
 
 <p>Originally published in <a href='http://genesdev.cshlp.org/content/35/9-10/692'>Genes &amp; Development</a>.</p>
 
 </div>
-<div *ngIf="panelId == 174">
+<div *ngIf="panelId == 175">
 <p>The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/55694'>eLife</a>. Image from <a href="https://elifesciences.org/articles/55694#fig6">eLife 2020;9:e55694</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 175">
+<div *ngIf="panelId == 176">
 <p>Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/srep44257'>Scientific Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 176">
+<div *ngIf="panelId == 177">
 <p>Dri1 mediates heterochromatin assembly via RNAi and histone deacetylation.</p>
 
 <p>Originally published in <a href='https://doi.org/10.1093/genetics/iyab032'>Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 177">
+<div *ngIf="panelId == 178">
 <p>Deletion of the non-essential Rpb9 subunit of RNA polymerase II results in pleiotropic phenotypes in Schizosaccharomyces pombe.</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S1570963921000601'>Biochimica et Biophysica Acta</a>.</p>
 
 </div>
-<div *ngIf="panelId == 178">
+<div *ngIf="panelId == 179">
 <p>Substrate specificities of α1,2- and α1,3-galactosyltransferases and characterization of Gmh1p and Otg1p in Schizosaccharomyces pombe.</p>
 
 <p>Originally published in <a href='https://doi.org/10.1093/glycob/cwab028'>Glycobiology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 179">
+<div *ngIf="panelId == 180">
 <p>Increased expression of Polδ does not alter the canonical replication program in vivo.</p>
 
 <p>Originally published in <a href='https://wellcomeopenresearch.org/articles/6-44/v2'>Wellcome Open Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 180">
+<div *ngIf="panelId == 181">
 <p>Dual Impact of a Benzimidazole Resistant β-Tubulin on Microtubule Behavior in Fission Yeast.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/2073-4409/10/5/1042/htm'>Cells</a>.</p>
 
 </div>
-<div *ngIf="panelId == 181">
+<div *ngIf="panelId == 182">
 <p>The histone H3K9M mutation synergizes with H3K14 ubiquitylation to selectively sequester histone H3K9 methyltransferase Clr4 at heterochromatin.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00476-9'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 182">
+<div *ngIf="panelId == 183">
 <p>Magnesium depletion extends fission yeast lifespan via general amino acid control activation.</p>
 
 <p>Originally published in <a href='https://onlinelibrary.wiley.com/doi/10.1002/mbo3.1176'>MicrobiologyOpen</a>.</p>
 
 </div>
-<div *ngIf="panelId == 183">
+<div *ngIf="panelId == 184">
 <p>The Putative RNA-Binding Protein Dri1 Promotes the Loading of Kinesin-14/Klp2 to the Mitotic Spindle and Is Sequestered into Heat-Induced Protein Aggregates in Fission Yeast.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/1422-0067/22/9/4795'>International Journal of Molecular Sciences</a>.</p>
 
 </div>
-<div *ngIf="panelId == 184">
+<div *ngIf="panelId == 185">
 <p>Linear elements are stable structures along the chromosome axis in fission yeast meiosis.</p>
 
 <p>Originally published in <a href='https://link.springer.com/article/10.1007%2Fs00412-021-00757-w'>Chromosoma</a>.</p>
 
 </div>
-<div *ngIf="panelId == 185">
+<div *ngIf="panelId == 186">
 <p>Identification of sur2 mutation affecting the lifespan of fission yeast.</p>
 
 <p>Originally published in <a href='https://doi.org/10.1093/femsle/fnab070'>FEMS Microbiology Letters</a>.</p>
 
 </div>
-<div *ngIf="panelId == 186">
+<div *ngIf="panelId == 187">
 <p>A conserved Ctp1/CtIP C-terminal peptide stimulates Mre11 endonuclease activity.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/content/118/11/e2016287118'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 187">
+<div *ngIf="panelId == 188">
 <p>Expression of Mug14 is regulated by the transcription factor Rst2 through the cAMP-dependent protein kinase pathway in Schizosaccharomyces pombe.</p>
 
 <p>Originally published in <a href='https://link.springer.com/article/10.1007%2Fs00294-021-01194-z'>Current Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 188">
+<div *ngIf="panelId == 189">
 <p>The intra-S phase checkpoint directly regulates replication elongation to preserve the integrity of stalled replisomes.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/content/118/24/e2019183118'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 189">
+<div *ngIf="panelId == 190">
 <p>TORC2 inhibition of α-arrestin Aly3 mediates cell surface persistence of S. pombe Ght5 glucose transporter in low glucose.</p>
 
 <p>Originally published in <a href='https://journals.biologists.com/jcs/article-abstract/134/10/jcs257485/268339/TORC2-inhibition-of-arrestin-Aly3-mediates-cell?redirectedFrom=fulltext'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 190">
+<div *ngIf="panelId == 191">
 <p>Single-Molecule Imaging Reveals the Mechanism Underlying Histone Loading of Schizosaccharomyces pombe AAA+ ATPase Abo1. (Image from <a href="https://www.pombase.org/reference/PMID:31848341">Cho et al. 2019</a>).</p>
 
 <p>Originally published in <a href='http://www.molcells.org/journal/view.html?doi=10.14348/molcells.2021.2242'>Molecules and Cells</a>.</p>
 
 </div>
-<div *ngIf="panelId == 191">
+<div *ngIf="panelId == 192">
 <p>Spatial sequestration of misfolded proteins as an active chaperone-mediated process during heat stress.</p>
 
 <p>Originally published in <a href='https://link.springer.com/article/10.1007%2Fs00294-020-01135-2'>Current Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 192">
+<div *ngIf="panelId == 193">
 <p>Regulation of inorganic polyphosphate is required for proper vacuolar proteolysis in fission yeast.</p>
 
 <p>Originally published in <a href='https://www.jbc.org/article/S0021-9258(21)00691-8/fulltext'>Journal of Biological Chemistry</a>.</p>
 
 </div>
-<div *ngIf="panelId == 193">
+<div *ngIf="panelId == 194">
 <p>Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/60969'>eLife</a>. Image from <a href="https://elifesciences.org/articles/60969#fig6">eLife 2021;10:e60969</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 194">
+<div *ngIf="panelId == 195">
 <p>Mapping and Analysis of Swi5 and Sfr1 Phosphorylation Sites.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/2073-4425/12/7/1014/htm'>Genes</a>.</p>
 
 </div>
-<div *ngIf="panelId == 195">
+<div *ngIf="panelId == 196">
 <p>Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.</p>
 
 <p>Originally published in <a href='https://doi.org/10.15252/embj.2020107497'>The EMBO Journal</a>.</p>
 
 </div>
-<div *ngIf="panelId == 196">
+<div *ngIf="panelId == 197">
 <p>Molecular organization of cytokinesis node predicts the constriction rate of the contractile ring..</p>
 
 <p>Originally published in <a href='https://rupress.org/jcb/article-abstract/220/3/e202008032/211718/Molecular-organization-of-cytokinesis-node?redirectedFrom=fulltext'>Journal of Cell Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 197">
+<div *ngIf="panelId == 198">
 <p>Phosphorylation in the intrinsically disordered region of F-BAR protein Imp2 regulates its contractile ring recruitment.</p>
 
 <p>Originally published in <a href='https://journals.biologists.com/jcs/article-abstract/doi/10.1242/jcs.258645/270972/Phosphorylation-in-the-intrinsically-disordered?redirectedFrom=fulltext'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 198">
+<div *ngIf="panelId == 199">
 <p>Identification of Nrl1 Domains Responsible for Interactions with RNA-Processing Factors and Regulation of Nrl1 Function by Phosphorylation.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/1422-0067/22/13/7011'>International Journal of Molecular Sciences</a>.</p>
 
 </div>
-<div *ngIf="panelId == 199">
+<div *ngIf="panelId == 200">
 <p>The INO80 Complex Regulates Epigenetic Inheritance of Heterochromatin.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31550-3'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 200">
+<div *ngIf="panelId == 201">
 <p>The cooperative assembly of shelterin bridge provides a kinetic gateway that controls telomere length homeostasis.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab550/6320402'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 201">
+<div *ngIf="panelId == 202">
 <p>Fission yeast Rad8/HLTF facilitates Rad52-dependent chromosomal rearrangements through PCNA lysine 107 ubiquitination.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009671'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 202">
+<div *ngIf="panelId == 203">
 <p>Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009526'>PLoS Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 203">
+<div *ngIf="panelId == 204">
 <p>Identification of ksg1 mutation showing long-lived phenotype in fission yeast.</p>
 
 <p>Originally published in <a href='https://onlinelibrary.wiley.com/doi/epdf/10.1111/gtc.12897'>Genes to Cells</a>.</p>
 
 </div>
-<div *ngIf="panelId == 204">
+<div *ngIf="panelId == 205">
 <p>Fission yeast TOR complex 1 phosphorylates Psk1 through evolutionarily conserved interaction mediated by the TOS motif.</p>
 
 <p>Originally published in <a href='https://journals.biologists.com/jcs/article/doi/10.1242/jcs.258865/272125/Fission-yeast-TOR-complex-1-phosphorylates-Psk1'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 205">
+<div *ngIf="panelId == 206">
 <p>Loss of kinesin-8 improves the robustness of the self-assembled spindle in Schizosaccharomyces pombe.</p>
 
 <p>Originally published in <a href='https://journals.biologists.com/jcs/article/134/16/jcs253799/271911/Loss-of-kinesin-8-improves-the-robustness-of-the'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 206">
+<div *ngIf="panelId == 207">
 <p>Visual detection of binary, ternary and quaternary protein interactions in fission yeast using a Pil1 co-tethering assay.</p>
 
 <p>Originally published in <a href='https://journals.biologists.com/jcs/article-abstract/134/19/jcs258774/272452/Visual-detection-of-binary-ternary-and-quaternary'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 207">
+<div *ngIf="panelId == 208">
 <p>The TOR-dependent phosphoproteome and regulation of cellular protein synthesis..</p>
 
 <p>Originally published in <a href='https://www.embopress.org/doi/full/10.15252/embj.2021107911'>EMBO Journal</a>.</p>
 
 </div>
-<div *ngIf="panelId == 208">
+<div *ngIf="panelId == 209">
 <p>Co-transcriptional RNA cleavage by Drosha homolog Pac1 triggers transcription termination in fission yeast.</p>
 
 <p>Originally published in Nucleic Acids Research <a href='https://academic.oup.com/nar/article/49/15/8610/6342457'></a>.</p>
 
 </div>
-<div *ngIf="panelId == 209">
+<div *ngIf="panelId == 210">
 <p>SUV39 SET domains mediate crosstalk of heterochromatic histone marks.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/62682'>eLife</a>. Image from <a href="https://elifesciences.org/articles/62682#fig2">eLife 2021;10:e62682</a>, used under <a href="https://creativecommons.org/licenses/by/4.0/">CC-BY</a> license terms.</p>
 
 </div>
-<div *ngIf="panelId == 210">
+<div *ngIf="panelId == 211">
 <p>Quality-Control Mechanism for Telomerase RNA Folding in the Cell.</p>
 
 <p>Originally published in <a href='https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31557-6'>Cell Reports</a>.</p>
 
 </div>
-<div *ngIf="panelId == 211">
+<div *ngIf="panelId == 212">
 <p>Counting actin in contractile rings reveals novel contributions of cofilin and type II myosins to fission yeast cytokinesis..</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/10.1091/mbc.E21-08-0376'>Mol Biol Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 212">
+<div *ngIf="panelId == 213">
 <p>The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states.</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S2211124721014170'>Cell Rep</a>.</p>
 
 </div>
-<div *ngIf="panelId == 213">
+<div *ngIf="panelId == 214">
 <p>Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation.</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/pii/S1097276521009539?via%3Dihub'>Mol Cell.</a>.</p>
 
 </div>
-<div *ngIf="panelId == 214">
+<div *ngIf="panelId == 215">
 <p>Activation of meiotic recombination by nuclear import of the DNA break hotspot-determining complex.</p>
 
 <p>Originally published in <a href='https://journals.biologists.com/jcs/article/134/4/jcs253518/237380/Activation-of-meiotic-recombination-by-nuclear'>J Cell Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 215">
+<div *ngIf="panelId == 216">
 <p>Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/content/118/33/e2108105118'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 216">
+<div *ngIf="panelId == 217">
 <p>Structure of Fission Yeast Transcription Factor Pho7 Bound to pho1 Promoter DNA and Effect of Pho7 Mutations on DNA Binding and Phosphate Homeostasis.</p>
 
 <p>Originally published in <a href='https://journals.asm.org/doi/10.1128/MCB.00132-19'>Mol. Cell. Biol.</a>.</p>
 
 </div>
-<div *ngIf="panelId == 217">
+<div *ngIf="panelId == 218">
 <p>The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability.</p>
 
 <p>Originally published in <a href='https://linkinghub.elsevier.com/retrieve/pii/S2589004221013079'>iScience</a>.</p>
 
 </div>
-<div *ngIf="panelId == 218">
+<div *ngIf="panelId == 219">
 <p>The Ceramide Synthase Subunit Lac1 Regulates Cell Growth and Size in Fission Yeast.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/1422-0067/23/1/303'>Int J Mol Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 219">
+<div *ngIf="panelId == 220">
 <p>R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009784'>PLoS Genet</a>.</p>
 
 </div>
-<div *ngIf="panelId == 220">
+<div *ngIf="panelId == 221">
 <p>Size-Dependent Expression of the Mitotic Activator Cdc25 Suggests a Mechanism of Size Control in Fission Yeast.</p>
 
 <p>Originally published in <a href='https://linkinghub.elsevier.com/retrieve/pii/S0960982217304256'>Curr. Biol.</a>.</p>
 
 </div>
-<div *ngIf="panelId == 221">
+<div *ngIf="panelId == 222">
 <p>A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.</p>
 
 <p>Originally published in <a href='https://royalsocietypublishing.org/doi/10.1098/rsob.200405'>Open Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 222">
+<div *ngIf="panelId == 223">
 <p>TOR complex 2 contributes to regulation of gene expression via inhibiting Gcn5 recruitment to subtelomeric and DNA replication stress genes.</p>
 
 <p>Originally published in <a href='https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010061'>PLoS Genet</a>.</p>
 
 </div>
-<div *ngIf="panelId == 223">
+<div *ngIf="panelId == 224">
 <p>Dicer promotes genome stability via the bromodomain transcriptional co-activator BRD4.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-022-28554-8'>Nat Commun</a>.</p>
 
 </div>
-<div *ngIf="panelId == 224">
+<div *ngIf="panelId == 225">
 <p>Involvement of Smi1 in cell wall integrity and glucan synthase Bgs4 localization during fission yeast cytokinesis..</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/10.1091/mbc.E21-04-0214'>Mol Biol Cell </a>.</p>
 
 </div>
-<div *ngIf="panelId == 225">
+<div *ngIf="panelId == 226">
 <p>Canavanine resistance mutation can1-1 in Schizosaccharomyces pombe is a missense mutation in the ubiquitin ligase adaptor gene any1.</p>
 
 <p>Originally published in <a href='https://www.micropublication.org/journals/biology/micropub-biology-000538'>MicroPubl Biol </a>.</p>
 
 </div>
-<div *ngIf="panelId == 226">
+<div *ngIf="panelId == 227">
 <p>Cdc48 influence on separase levels is independent of mitosis and suggests translational sensitivity of separase.</p>
 
 <p>Originally published in <a href='https://linkinghub.elsevier.com/retrieve/pii/S2211124722002984'>Cell Rep.</a>.</p>
 
 </div>
-<div *ngIf="panelId == 227">
+<div *ngIf="panelId == 228">
 <p>Rec8 Cohesin-mediated Axis-loop chromatin architecture is required for meiotic recombination.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/50/7/3799/6554166'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 228">
+<div *ngIf="panelId == 229">
 <p>Microtubule rescue at midzone edges promotes overlap stability and prevents spindle collapse during anaphase B.</p>
 
 <p>Originally published in <a href='https://elifesciences.org/articles/72630'>Elife</a>.</p>
 
 </div>
-<div *ngIf="panelId == 229">
+<div *ngIf="panelId == 230">
 <p>The actin assembly requirements of the formin Fus1 to build the fusion focus.</p>
 
 <p>Originally published in <a href='https://doi.org/10.1242/jcs.260289'>Journal of Cell Science</a>.</p>
 
 </div>
-<div *ngIf="panelId == 230">
+<div *ngIf="panelId == 231">
 <p>The methyl phosphate capping enzyme Bmc1/Bin3 is a stable component of the fission yeast telomerase holoenzyme.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-022-28985-3'>Nature Communications</a>.</p>
 
 </div>
-<div *ngIf="panelId == 231">
+<div *ngIf="panelId == 232">
 <p>Mitotic spindle formation in the absence of Polo kinase.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/doi/full/10.1073/pnas.2114429119'>PNAS</a>.</p>
 
 </div>
-<div *ngIf="panelId == 232">
+<div *ngIf="panelId == 233">
 <p>Fission stories: using PomBase to understand Schizosaccharomyces pombe biology.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyab222/6481557'>Genetics</a>.</p>
 
 </div>
-<div *ngIf="panelId == 233">
+<div *ngIf="panelId == 234">
 <p>Isolated THATCH domain of End4 is unable to bind F-actin independently in the fission yeast Schizosaccharomyces pombe.</p>
 
 <p>Originally published in <a href='https://www.micropublication.org/journals/biology/micropub-biology-000508'>MicroPubl</a>.</p>
 
 </div>
-<div *ngIf="panelId == 234">
+<div *ngIf="panelId == 235">
 <p>Characterization of canavanine-resistance of cat1 and vhc1 deletions and a dominant any1 mutation in fission yeast.</p>
 
 <p>Originally published in <a href='https://www.pombase.org/reference/PMID:35639710'>PLoS One</a>.</p>
 
 </div>
-<div *ngIf="panelId == 235">
+<div *ngIf="panelId == 236">
 <p>Arf6 anchors Cdr2 nodes at the cell cortex to control cell size at division..</p>
 
 <p>Originally published in <a href='https://rupress.org/jcb/article/221/2/e202109152/212942/Arf6-anchors-Cdr2-nodes-at-the-cell-cortex-to'>JCB</a>.</p>
 
 </div>
-<div *ngIf="panelId == 236">
+<div *ngIf="panelId == 237">
 <p>Coordinated cortical ER remodeling facilitates actomyosin ring assembly.</p>
 
 <p>Originally published in <a href='https://www.cell.com/current-biology/fulltext/S0960-9822(22)00722-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982222007229%3Fshowall%3Dtrue'>Current Biology</a>.</p>
 
 </div>
-<div *ngIf="panelId == 237">
+<div *ngIf="panelId == 238">
 <p>Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast.</p>
 
 <p>Originally published in <a href='https://www.cell.com/developmental-cell/fulltext/S1534-5807(21)00768-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1534580721007681%3Fshowall%3Dtrue'>Dev Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 238">
+<div *ngIf="panelId == 239">
 <p>Ccp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly.</p>
 
 <p>Originally published in <a href='https://www.pnas.org/doi/full/10.1073/pnas.2104459118'>Proc Natl Acad Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 239">
+<div *ngIf="panelId == 240">
 <p>Queuosine salvage in fission yeast by Qng1-mediated hydrolysis to queuine.</p>
 
 <p>Originally published in <a href='https://www.sciencedirect.com/science/article/abs/pii/S0006291X22010919?via%3Dihub'>Biochem Biophys Res Commun</a>.</p>
 
 </div>
-<div *ngIf="panelId == 240">
+<div *ngIf="panelId == 241">
 <p>Queuine links translational control in eukaryotes to a micronutrient from bacteria.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/47/7/3711/5305261'>Nucleic Acids Res.</a>.</p>
 
 </div>
-<div *ngIf="panelId == 241">
+<div *ngIf="panelId == 242">
 <p>Brc1 Promotes the Focal Accumulation and SUMO Ligase Activity of Smc5-Smc6 during Replication Stress.</p>
 
 <p>Originally published in <a href='https://journals.asm.org/doi/10.1128/MCB.00271-18'>Mol. Cell. Biol.</a>.</p>
 
 </div>
-<div *ngIf="panelId == 242">
+<div *ngIf="panelId == 243">
 <p>The Mis6 inner kinetochore subcomplex maintains CENP-A nucleosomes against centromeric non-coding transcription during mitosis.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s42003-022-03786-y'>Commun Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 243">
+<div *ngIf="panelId == 244">
 <p>Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/2073-4409/11/1/165'>Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 244">
+<div *ngIf="panelId == 245">
 <p>Inactivation of fission yeast Erh1 de-represses pho1 expression: evidence that Erh1 is a negative regulator of prt lncRNA termination</p>
 
 <p>Originally published in <a href='https://rnajournal.cshlp.org/content/26/10/1334'>RNA</a>.</p>
 
 </div>
-<div *ngIf="panelId == 245">
+<div *ngIf="panelId == 246">
 <p>Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase-pyrophosphatases that act via a covalent aspartyl-phosphate intermediate.</p>
 
 <p>Originally published in <a href='https://www.jbc.org/article/S0021-9258(22)00291-5/fulltext'>J Biol Chem</a>.</p>
 
 </div>
-<div *ngIf="panelId == 246">
+<div *ngIf="panelId == 247">
 <p>Inositol pyrophosphates impact phosphate homeostasis via modulation of RNA 3’ processing and transcription termination.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/47/16/8452/5528736'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 247">
+<div *ngIf="panelId == 248">
 <p>Genetic screen for suppression of transcriptional interference reveals fission yeast 14-3-3 protein Rad24 as an antagonist of precocious Pol2 transcription termination.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/50/2/803/6489952'>Nucleic Acids Research</a>.</p>
 
 </div>
-<div *ngIf="panelId == 248">
+<div *ngIf="panelId == 249">
 <p>Transcriptional profiling of fission yeast RNA polymerase II CTD mutants.</p>
 
 <p>Originally published in <a href='https://rnajournal.cshlp.org/content/27/5/560'>RNA</a>.</p>
 
 </div>
-<div *ngIf="panelId == 249">
+<div *ngIf="panelId == 250">
 <p>Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3’ processing and transcription termination that functions via its effects on CTD phosphatase Ssu72.</p>
 
 <p>Originally published in <a href='https://academic.oup.com/nar/article/48/9/4811/5819598'>Nucleic Acids Res.</a>.</p>
 
 </div>
-<div *ngIf="panelId == 250">
+<div *ngIf="panelId == 251">
 <p>Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast..</p>
 
 <p>Originally published in <a href='https://journals.asm.org/doi/10.1128/mbio.03476-21'>mBio</a>.</p>
 
 </div>
-<div *ngIf="panelId == 251">
+<div *ngIf="panelId == 252">
 <p>Interactome of Spliceosome-Associated G-Patch Protein Gpl1 in the Fission Yeast Schizosaccharomyces pombe.</p>
 
 <p>Originally published in <a href='https://www.mdpi.com/1422-0067/23/21/12800'>Int J Mol Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 252">
+<div *ngIf="panelId == 253">
 <p>Recovery from spindle checkpoint-mediated arrest requires a novel Dnt1-dependent APC/C activation mechanism.</p>
 
 <p>Originally published in <a href='https://www.pombase.org/reference/PMID:36108046'>PLoS Genet</a>.</p>
 
 </div>
-<div *ngIf="panelId == 253">
+<div *ngIf="panelId == 254">
 <p>Ubiquitination of CLIP-170 family protein restrains polarized growth upon DNA replication stress.</p>
 
 <p>Originally published in <a href='https://www.nature.com/articles/s41467-022-33311-y'>Nat Commun</a>.</p>
 
 </div>
-<div *ngIf="panelId == 254">
+<div *ngIf="panelId == 255">
 <p>Membrane stretching activates calcium-permeability of a putative channel Pkd2 during fission yeast cytokinesis..</p>
 
 <p>Originally published in <a href='https://www.molbiolcell.org/doi/10.1091/mbc.E22-07-0248'>Molecular Biology of the Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 255">
+<div *ngIf="panelId == 256">
 <p>Diacylglycerol at the inner nuclear membrane fuels nuclear envelope expansion in closed mitosis..</p>
 
 <p>Originally published in <a href='https://journals.biologists.com/jcs/article/136/3/jcs260568/286881/Diacylglycerol-at-the-inner-nuclear-membrane-fuels'>J Cell Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 256">
+<div *ngIf="panelId == 257">
 <p>An ecl family gene ecl3+ is induced by phosphate starvation and contributes to sexual differentiation in fission yeast..</p>
 
 <p>Originally published in <a href='https://journals.biologists.com/jcs/article/doi/10.1242/jcs.260759/287015/An-ecl-family-gene-ecl3-is-induced-by-phosphate'>J Cell Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 257">
+<div *ngIf="panelId == 258">
 <p>Analysis of the potential role of fission yeast PP2A in spindle assembly checkpoint inactivation.</p>
 
 
@@ -1628,7 +1636,7 @@
 <p>Originally published in <a href='https://doi.org/10.1096/fj.202101884R'>FASEB J</a>.</p>
 
 </div>
-<div *ngIf="panelId == 258">
+<div *ngIf="panelId == 259">
 <p>Mechanistic insights into the anchorage of the contractile ring by anillin and Mid1.</p>
 
 
@@ -1636,7 +1644,7 @@
 <p>Originally published in <a href='https://doi.org/10.1016/j.devcel.2015.03.003'>Dev Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 259">
+<div *ngIf="panelId == 260">
 <p>Cryo-EM structure and function of S. pombe complex IV with bound respiratory supercomplex factor.</p>
 
 
@@ -1644,7 +1652,7 @@
 <p>Originally published in <a href='https://doi.org/10.1038/s42004-023-00827-3'>Commun Chem</a>.</p>
 
 </div>
-<div *ngIf="panelId == 260">
+<div *ngIf="panelId == 261">
 <p>Tandemly repeated genes promote RNAi-mediated heterochromatin formation via an antisilencing factor, Epe1, in fission yeast.</p>
 
 
@@ -1652,7 +1660,7 @@
 <p>Originally published in <a href='https://doi.org/10.1101/gad.350129.122'>Genes Dev</a>.</p>
 
 </div>
-<div *ngIf="panelId == 261">
+<div *ngIf="panelId == 262">
 <p>The fission yeast kinetochore complex Mhf1-Mhf2 regulates the spindle assembly checkpoint and faithful chromosome segregation.</p>
 
 
@@ -1660,7 +1668,7 @@
 <p>Originally published in <a href='https://doi.org/10.1242/jcs.260124'>J Cell Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 262">
+<div *ngIf="panelId == 263">
 <p>Critical role of Wat1/Pop3 in regulating the TORC1 signalling pathway in fission yeast S. pombe.</p>
 
 
@@ -1668,7 +1676,7 @@
 <p>Originally published in <a href='https://doi.org/10.1016/j.fgb.2022.103764'>Fungal Genet Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 263">
+<div *ngIf="panelId == 264">
 <p>Inner nuclear membrane proteins Lem2 and Bqt4 interact with different lipid synthesis enzymes in fission yeast.</p>
 
 
@@ -1676,7 +1684,7 @@
 <p>Originally published in <a href='https://doi.org/10.1093/jb/mvad017'>J Biochem</a>.</p>
 
 </div>
-<div *ngIf="panelId == 264">
+<div *ngIf="panelId == 265">
 <p>Hva22, a REEP family protein in fission yeast, promotes reticulophagy in collaboration with a receptor protein.</p>
 
 
@@ -1684,7 +1692,7 @@
 <p>Originally published in <a href='https://doi.org/10.1080/15548627.2023.2214029'>Autophagy</a>.</p>
 
 </div>
-<div *ngIf="panelId == 265">
+<div *ngIf="panelId == 266">
 <p>The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy.</p>
 
 
@@ -1692,7 +1700,7 @@
 <p>Originally published in <a href='https://doi.org/10.1016/j.molcel.2023.04.022'>Mol Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 266">
+<div *ngIf="panelId == 267">
 <p>Force by minus-end motors Dhc1 and Klp2 collapses the S. pombe spindle after laser ablation.</p>
 
 
@@ -1700,7 +1708,7 @@
 <p>Originally published in <a href='https://doi.org/10.1016/j.bpj.2021.12.019'>Biophys J</a>.</p>
 
 </div>
-<div *ngIf="panelId == 267">
+<div *ngIf="panelId == 268">
 <p>Identification of novel coenzyme Q10 biosynthetic proteins Coq11 and Coq12 in Schizosaccharomyces pombe.</p>
 
 
@@ -1708,7 +1716,7 @@
 <p>Originally published in <a href='https://doi.org/10.1016/j.jbc.2023.104797'>J Biol Chem</a>.</p>
 
 </div>
-<div *ngIf="panelId == 268">
+<div *ngIf="panelId == 269">
 <p>Fission yeast Srr1 and Skb1 promote isochromosome formation at the centromere.</p>
 
 
@@ -1716,7 +1724,7 @@
 <p>Originally published in <a href='https://doi.org/10.1038/s42003-023-04925-9'>Commun Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 269">
+<div *ngIf="panelId == 270">
 <p>Chiasmata and the kinetochore component Dam1 are crucial for elimination of erroneous chromosome attachments and centromere oscillation at meiosis I.</p>
 
 
@@ -1724,7 +1732,7 @@
 <p>Originally published in <a href='https://doi.org/10.1098/rsob.200308'>Open Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 270">
+<div *ngIf="panelId == 271">
 <p>Direct evaluation of cohesin-mediated sister kinetochore associations at meiosis I in fission yeast.</p>
 
 
@@ -1732,7 +1740,7 @@
 <p>Originally published in <a href='https://doi.org/10.1242/jcs.259102'>J Cell Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 271">
+<div *ngIf="panelId == 272">
 <p>The fission yeast cytokinetic ring component Fic1 promotes septum formation.</p>
 
 
@@ -1740,7 +1748,7 @@
 <p>Originally published in <a href='https://doi.org/10.1242/bio.059957'>Biol Open</a>.</p>
 
 </div>
-<div *ngIf="panelId == 272">
+<div *ngIf="panelId == 273">
 <p>Optimization of energy production and central carbon metabolism in a non-respiring eukaryote.</p>
 
 
@@ -1748,7 +1756,7 @@
 <p>Originally published in <a href='https://doi.org/10.1016/j.cub.2023.04.046'>Curr Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 273">
+<div *ngIf="panelId == 274">
 <p>Unraveling the kinetochore nanostructure in Schizosaccharomyces pombe using multi-color SMLM imaging.</p>
 
 
@@ -1756,7 +1764,7 @@
 <p>Originally published in <a href='https://doi.org/10.1083/jcb.202209096'>J Cell Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 274">
+<div *ngIf="panelId == 275">
 <p>Mitotic checkpoint gene expression is tuned by codon usage bias.</p>
 
 
@@ -1764,7 +1772,7 @@
 <p>Originally published in <a href='https://doi.org/10.15252/embj.2021107896'>EMBO J</a>.</p>
 
 </div>
-<div *ngIf="panelId == 275">
+<div *ngIf="panelId == 276">
 <p>CDK actively contributes to establishment of the stationary phase state in fission yeast.</p>
 
 
@@ -1772,7 +1780,7 @@
 <p>Originally published in <a href='https://doi.org/10.1242/jcs.260727'>J Cell Sci</a>.</p>
 
 </div>
-<div *ngIf="panelId == 276">
+<div *ngIf="panelId == 277">
 <p>The fission yeast methyl phosphate capping enzyme Bmc1 guides 2’-O-methylation of the U6 snRNA.</p>
 
 
@@ -1780,7 +1788,7 @@
 <p>Originally published in <a href='https://doi.org/10.1093/nar/gkad563'>Nucleic Acids Res</a>.</p>
 
 </div>
-<div *ngIf="panelId == 277">
+<div *ngIf="panelId == 278">
 <p>Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins.</p>
 
 
@@ -1788,7 +1796,7 @@
 <p>Originally published in <a href='https://doi.org/10.1091/mbc.E23-06-0233'>Mol Biol Cell</a>.</p>
 
 </div>
-<div *ngIf="panelId == 278">
+<div *ngIf="panelId == 279">
 <p>Completion of mitochondrial division requires the intermembrane space protein Mdi1/Atg44.</p>
 
 
@@ -1796,7 +1804,7 @@
 <p>Originally published in <a href='https://doi.org/10.1083/jcb.202303147'>J Cell Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 279">
+<div *ngIf="panelId == 280">
 <p>Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.</p>
 
 
@@ -1804,7 +1812,7 @@
 <p>Originally published in <a href='https://doi.org/10.1093/nar/gkad063'>Nucleic Acids Res</a>.</p>
 
 </div>
-<div *ngIf="panelId == 280">
+<div *ngIf="panelId == 281">
 <p>Splicing of branchpoint-distant exons is promoted by Cactin, Tls1 and the ubiquitin-fold-activated Sde2.</p>
 
 
@@ -1812,7 +1820,7 @@
 <p>Originally published in <a href='https://doi.org/10.1093/nar/gkac769'>Nucleic Acids Res</a>.</p>
 
 </div>
-<div *ngIf="panelId == 281">
+<div *ngIf="panelId == 282">
 <p>The AAA-ATPase Yta4/ATAD1 interacts with the mitochondrial divisome to inhibit mitochondrial fission.</p>
 
 
@@ -1820,7 +1828,7 @@
 <p>Originally published in <a href='https://doi.org/10.1371/journal.pbio.3002247'>PLoS Biol</a>.</p>
 
 </div>
-<div *ngIf="panelId == 282">
+<div *ngIf="panelId == 283">
 <p>Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast.</p>
 
 
@@ -1828,7 +1836,7 @@
 <p>Originally published in <a href='https://doi.org/10.1038/s41467-019-13243-w'>Nat Commun</a>.</p>
 
 </div>
-<div *ngIf="panelId == 283">
+<div *ngIf="panelId == 284">
 <p>The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly.</p>
 
 
@@ -1836,7 +1844,7 @@
 <p>Originally published in <a href='https://doi.org/10.1016/j.celrep.2021.109867'>Cell Rep</a>.</p>
 
 </div>
-<div *ngIf="panelId == 284">
+<div *ngIf="panelId == 285">
 <p>Cooperative DNA-binding activities of Chp2 are critical for its function in heterochromatin assembly.</p>
 
 
@@ -1844,51 +1852,51 @@
 <p>Originally published in <a href='https://doi.org/10.1093/jb/mvad050'>J Biochem</a>.</p>
 
 </div>
-<div *ngIf="panelId == 285">
+<div *ngIf="panelId == 286">
 <p><app-recent-community-pubs></app-recent-community-pubs></p>
 
 </div>
-<div *ngIf="panelId == 286">
+<div *ngIf="panelId == 287">
 <p><app-recent-community-pubs></app-recent-community-pubs></p>
 
 </div>
-<div *ngIf="panelId == 287">
+<div *ngIf="panelId == 288">
 <p>Browse PomBase’s inventory of conserved proteins with no known biological role</p>
 
 </div>
-<div *ngIf="panelId == 288">
+<div *ngIf="panelId == 289">
 <p>The fission yeast <a routerLink="/browse-curation/fission-yeast-go-slim-terms">GO slim</a> provides a summary of genes annotated to broad biological processes</p>
 
 </div>
-<div *ngIf="panelId == 289">
+<div *ngIf="panelId == 290">
 <p>Use the <a routerLink="/query">Advanced Search</a> to construct complex queries (GO, phenotypes, taxonomic distribution, domain, chromosomal location).</p>
 
 </div>
-<div *ngIf="panelId == 290">
+<div *ngIf="panelId == 291">
 <p>PomBase has integrated over 200,000 manually curated gene-specific annotations. See our <a routerLink="/about/resource-metrics">Resource Metrics</a> page for more literature curation progress reports.</p>
 
 </div>
-<div *ngIf="panelId == 291">
+<div *ngIf="panelId == 292">
 <p>PomBase uses manually curated Gene Ontology annotation to generate biological process-specific networks, such as the cytokinesis network excerpted above. Currently available networks are linked to the <a routerLink="/browse-curation/fission-yeast-go-slim-terms">GO slim</a> page.</p>
 
 </div>
-<div *ngIf="panelId == 292">
+<div *ngIf="panelId == 293">
 <p>PomBase provides extensive documentation and answers many questions in the <a routerLink="/faq">FAQ</a>. For any information you can’t find there, please <app-contact-email [linkName]="'contact the helpdesk'" [subject]="'PomBase question'"></app-contact-email>.</p>
 
 </div>
-<div *ngIf="panelId == 293">
+<div *ngIf="panelId == 294">
 <p>PomBase has pioneered a community curation system that enables researchers to contribute publication-based annotations directly to database curators. To participate, search for the PubMed ID of your paper <a href="https://curation.pombase.org/pombe">in Canto</a> or <app-contact-email [linkName]="'contact the helpdesk'" [subject]="'PomBase question'"></app-contact-email>.</p>
 
 </div>
-<div *ngIf="panelId == 294">
+<div *ngIf="panelId == 295">
 <p>4020 of the 5070 fission yeast protein-coding genes now have assigned standard names. We encourage all authors and reviewers to ensure that gene names are registered prior to publication. Visit our <a routerLink="/gene-names">gene registry page</a> and the <a routerLink="/gene-names/gene-naming-guidelines"><em>S. pombe</em> gene naming guidelines</a> for more information.</p>
 
 </div>
-<div *ngIf="panelId == 295">
+<div *ngIf="panelId == 296">
 <p>Of the 3526 <em>S. pombe</em> with identified human orthologs, over 500 have been implicated in disease. These are manually annotated with terms from a small in-house vocabulary, and can be searched as described in the <a routerLink="/faq/how-can-i-find-s.-pombe-genes-associated-human-disease">disease gene FAQ</a>.</p>
 
 </div>
-<div *ngIf="panelId == 296">
+<div *ngIf="panelId == 297">
 <p>A guide to getting the most from PomBase, and to its curation philosophy and data organization. <a href="https://link.springer.com/protocol/10.1007/978-1-4939-7737-6_4">Free download</a> thanks to the <a href="https://wellcome.ac.uk/">Wellcome Trust</a>.</p>
 
 
@@ -1896,53 +1904,53 @@
 <p><a href="https://link.springer.com/protocol/10.1007/978-1-4939-7737-6_4">View chapter …</a></p>
 
 </div>
-<div *ngIf="panelId == 297">
+<div *ngIf="panelId == 298">
 <p>Unknown process now down to 696, <a routerLink="/gene_subset/characterisation_status_conserved_unknown">conserved unknowns 410</a>.</p>
 
 <p>Our “Unknowns” manuscript is now available on bioRxiv: <a href="https://www.biorxiv.org/content/early/2018/11/16/469569">DOI: 10.1101/469569</a>.</p>
 
 </div>
-<div *ngIf="panelId == 298">
+<div *ngIf="panelId == 299">
 <p>Access <a routerLink="/term/MONDO:0000001">Disease associations</a> for 907 pombe genes (up from 610), includes new associations derived from MalaCards. This number will increase as work is still in progress…</p>
 
 </div>
-<div *ngIf="panelId == 299">
+<div *ngIf="panelId == 300">
 <p>Our “unknowns” analysis is now published in <a href="https://royalsocietypublishing.org/doi/10.1098/rsob.180241">Open Biology</a>. You can browse the <a routerLink="/status/priority-unstudied-genes">list of fission yeast unknown proteins</a>, and use the “Visualise” button to explore the data interactively in QuiLT, the new tool inspired by <a href="https://royalsocietypublishing.org/doi/10.1098/rsob.180241#RSOB180241F4">Figure 4</a>.</p>
 
 </div>
-<div *ngIf="panelId == 300">
+<div *ngIf="panelId == 301">
 <p>PomBase’s advanced search now allows you to retrieve <a routerLink="/documentation/pombase-go-slim-documentation">GO slim</a> annotations for any set of search results. Combine with the “Gene IDs” query option to find GO slim annotations for your own list of genes.</p>
 
 </div>
-<div *ngIf="panelId == 301">
+<div *ngIf="panelId == 302">
 <p>The PomBase <a routerLink="/motif_search">Protein Motif Search Tool</a> allows you to search for any user-defined amino acid sequence, supporting exact matches, wildcards, gaps, and ambiguity codes. This search is now fully integrated into PomBase, allowing results to be sent directly to the <a routerLink="/query">advanced search</a>.</p>
 
 </div>
-<div *ngIf="panelId == 302">
+<div *ngIf="panelId == 303">
 <p>The PomBase <a href="https://www.pombase.org/jbrowse/">JBrowse instance</a> provides a responsive online environment in which to visualise published genomic datasets. For more information please see our <a href="https://www.pombase.org/documentation/JBrowse_quick_start">JBrowse documentation page</a>. Authors are welcome to submit their published data to PomBase for hosting.</p>
 
 </div>
-<div *ngIf="panelId == 303">
+<div *ngIf="panelId == 304">
 <p>Authors now contribute curation to PomBase for almost all new fission yeast publications. Find out how you can benefit in our <a href="https://academic.oup.com/database/article/doi/10.1093/database/baaa028/5827230">new paper on community curation</a>, and visit the <a href="https://curation.pombase.org/pombe"><em>S. pombe</em> Canto home</a> to participate.</p>
 
 </div>
-<div *ngIf="panelId == 304">
+<div *ngIf="panelId == 305">
 <p>Access <a routerLink="/term/MONDO:0000001">Disease associations</a> for 1239 of the 3540 pombe genes with human orthologs (up from 987 in 2019), using the MONDO disease ontology. Or browse the <a href="https://www.pombase.org/browse-curation/disease-slim">disease slim set here</a>.</p>
 
 </div>
-<div *ngIf="panelId == 305">
+<div *ngIf="panelId == 306">
 <p><a href="https://www.micropublication.org/journals/biology/species/s-pombe/"><em>S. pombe</em> microPublications</a> describe brief, novel findings, negative and/or reproduced results, and results which may lack a broader scientific narrative. Find microPublications in the PomBase simple search, or <a href="https://www.micropublication.org/submit-new-article/">submit your own</a>.</p>
 
 </div>
-<div *ngIf="panelId == 306">
+<div *ngIf="panelId == 307">
 <p>Browse <a routerLink="/term/MONDO:0000001">Disease associations</a>, annotated using the Mondo disease ontology, for 1401 (up from 907 in 2019 and 1239 in 2020) of the 3560 <em>S. pombe</em> genes that have human orthologs. See the <a routerLink="/browse-curation/disease-slim">disease slim set</a> for a summary view.</p>
 
 </div>
-<div *ngIf="panelId == 307">
+<div *ngIf="panelId == 308">
 <p>Browse <a routerLink="/term/MONDO:0000001">Disease associations</a>, annotated using the Mondo disease ontology, for 1471 (up from 1401 in August 2021) of the 3597 <em>S. pombe</em> genes that have human orthologs. See the <a routerLink="/browse-curation/disease-slim">disease slim set</a> for a summary view.</p>
 
 </div>
-<div *ngIf="panelId == 308">
+<div *ngIf="panelId == 309">
 <p>We cloned PomBase to create a fully community-maintained resource for the <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789812/">emerging model S. japonicus</a>; providing genome browser, literature curation, and query tools.</p>
 
 
diff --git a/src/app/recent-news/recent-news.component.html b/src/app/recent-news/recent-news.component.html
index f296cccb..3589b201 100644
--- a/src/app/recent-news/recent-news.component.html
+++ b/src/app/recent-news/recent-news.component.html
@@ -1,6 +1,15 @@
 <div class="recent-news">
 <div class="news-item">
 <img loading="lazy" class="newsfeed-thumbnail" src="/assets/newsfeed/pombase-logo-32x32px.png"/>
+<h4 id="revised-fission-yeast-nomenclature-for-genes-and-alleles"><strong>Revised fission yeast nomenclature for genes and alleles</strong></h4>
+<p><em>2023-09-30</em></p>
+<p>The improved nomenclature guidelines for fission yeast clade genes and alleles have been <a href="https://academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyad143/7283026">published in Genetics GSA</a>. This update introduces nomenclature guidelines for noncoding RNA genes, a significant update to the allele and genotype nomenclature guidelines originally published in 1987. We took several steps to improve machine readability that will benefit the artificial intelligence/machine learning communities, and our own community curation program.</p>
+<p><a href="https://doi.org/10.1093/genetics/iyad143">Lera-Ramírez <em>et al.</em> 2023, Revised fission yeast gene and allele nomenclature guidelines for machine readability, Genetics, 2023;, iyad143</a></p>
+<p><a href="assets/newsfeed/nomenclature_paper_for_news_big.png"><img src="assets/newsfeed/nomenclature_paper_for_news.png" title="Revised fission yeast gene and allele nomenclature guidelines for machine readability" class="screenshot" style="width:100.0%" alt="“Revised fission yeast gene and allele nomenclature guidelines for machine readability”" /></a></p>
+
+</div>
+<div class="news-item">
+<img loading="lazy" class="newsfeed-thumbnail" src="/assets/newsfeed/pombase-logo-32x32px.png"/>
 <h4 id="accessing-the-list-of-genes-from-a-paper"><strong>Accessing the list of genes from a paper</strong></h4>
 <p><em>2023-09-20</em></p>
 <p>It’s now possible to view the list of genes associated with a paper, using a new link on the publication pages. The gene list can then optionally be sent to the Advanced Search.</p>