diff --git a/pkgs/development/python-modules/zenoh/default.nix b/pkgs/development/python-modules/zenoh/default.nix
new file mode 100644
index 0000000000000..cacc31f4e45ab
--- /dev/null
+++ b/pkgs/development/python-modules/zenoh/default.nix
@@ -0,0 +1,51 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  cargo,
+  rustPlatform,
+  rustc,
+  stdenv,
+  darwin,
+}:
+
+buildPythonPackage rec {
+  pname = "zenoh";
+  version = "1.0.3";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "eclipse-zenoh";
+    repo = "zenoh-python";
+    rev = version;
+    hash = "sha256-LQ6zu0yD2heprN2p6zO/ZC6uIsMlc1FyDuZ/dvOnVqU=";
+  };
+
+  cargoDeps = rustPlatform.fetchCargoVendor {
+    inherit src pname version;
+    hash = "sha256-6a2OSZLn1OYpe4tAv60uBhh/b+3QewPxVtQIDOnpk3A=";
+  };
+
+  build-system = [
+    cargo
+    rustPlatform.cargoSetupHook
+    rustPlatform.maturinBuildHook
+    rustc
+  ];
+
+  buildInputs = lib.optional stdenv.isDarwin darwin.apple_sdk.frameworks.Security;
+
+  pythonImportsCheck = [
+    "zenoh"
+  ];
+
+  meta = {
+    description = "Python API for zenoh";
+    homepage = "https://github.com/eclipse-zenoh/zenoh-python";
+    license = with lib.licenses; [
+      asl20
+      epl20
+    ];
+    maintainers = with lib.maintainers; [ markuskowa ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index caa3cb5763e67..c1682fcddad15 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -18298,6 +18298,8 @@ self: super: with self; {
     python3 = python;
   })).py;
 
+  zenoh = callPackage ../development/python-modules/zenoh { };
+
   zephyr-python-api = callPackage ../development/python-modules/zephyr-python-api { };
 
   zeroc-ice = callPackage ../development/python-modules/zeroc-ice { };