diff --git a/src/serializers/fields.rs b/src/serializers/fields.rs
index 32c16b18a..fa0b37580 100644
--- a/src/serializers/fields.rs
+++ b/src/serializers/fields.rs
@@ -75,9 +75,7 @@ impl SerField {
 fn exclude_default(value: &Bound<'_, PyAny>, extra: &Extra, serializer: &CombinedSerializer) -> PyResult<bool> {
     if extra.exclude_defaults {
         if let Some(default) = serializer.get_default(value.py())? {
-            if value.eq(default)? {
-                return Ok(true);
-            }
+            return Ok(value.eq(default).unwrap_or(false));
         }
     }
     Ok(false)
diff --git a/tests/serializers/test_typed_dict.py b/tests/serializers/test_typed_dict.py
index df507a248..608f84a55 100644
--- a/tests/serializers/test_typed_dict.py
+++ b/tests/serializers/test_typed_dict.py
@@ -170,6 +170,49 @@ def test_exclude_default():
     assert v.to_json({'foo': 1, 'bar': b'[default]'}, exclude_defaults=True) == b'{"foo":1}'
 
 
+def test_exclude_incomparable_default():
+    """Values that can't be compared with eq are treated as not equal to the default"""
+
+    def ser_x(*args):
+        return [1, 2, 3]
+
+    cls_schema = core_schema.any_schema(serialization=core_schema.plain_serializer_function_ser_schema(ser_x))
+
+    class Incomparable:
+        __pydantic_serializer__ = SchemaSerializer(cls_schema)
+
+        def __get_pydantic_core_schema__(*args):
+            return cls_schema
+
+        def __eq__(self, other):
+            raise NotImplementedError("Can't be compared!")
+
+    class NeqComparable(Incomparable):
+        def __eq__(self, other):
+            return False
+
+    class EqComparable(Incomparable):
+        def __eq__(self, other):
+            return True
+
+    v = SchemaSerializer(
+        core_schema.typed_dict_schema(
+            {
+                'foo': core_schema.typed_dict_field(
+                    core_schema.with_default_schema(core_schema.any_schema(), default=None)
+                ),
+            }
+        )
+    )
+
+    assert v.to_python({'foo': Incomparable()}, exclude_defaults=True)['foo'] == [1, 2, 3]
+    assert v.to_json({'foo': Incomparable()}, exclude_defaults=True) == b'{"foo":[1,2,3]}'
+    assert v.to_python({'foo': NeqComparable()}, exclude_defaults=True)['foo'] == [1, 2, 3]
+    assert v.to_json({'foo': NeqComparable()}, exclude_defaults=True) == b'{"foo":[1,2,3]}'
+    assert v.to_python({'foo': EqComparable()}, exclude_defaults=True) == {}
+    assert v.to_json({'foo': EqComparable()}, exclude_defaults=True) == b'{}'
+
+
 def test_function_plain_field_serializer_to_python():
     class Model(TypedDict):
         x: int