diff --git a/CHANGELOG.md b/CHANGELOG.md
index a45ec8c4c4..7f5443637a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,6 @@
 ## dev
 
+- Fix "Failed to delete" error when using Microsoft Store Python
 - Fix "No pyvenv.cfg file" error when using Microsoft Store Python (#1164)
 - Add `--quiet` and `--verbose` options for the `pipx` subcommands
 - [docs] Add Scoop installation instructions
diff --git a/src/pipx/util.py b/src/pipx/util.py
index 2a9965ef4b..4bba09d6f5 100644
--- a/src/pipx/util.py
+++ b/src/pipx/util.py
@@ -55,7 +55,9 @@ def rmdir(path: Path, safe_rm: bool = True) -> None:
     logger.info(f"removing directory {path}")
     try:
         if WINDOWS:
-            os.system(f'rmdir /S /Q "{str(path)}"')
+            # The packaged app (Microsoft Store) version of Python uses path redirections, but `rmdir` won't follow
+            # these, so use realpath() to manually apply the redirection first.
+            os.system(f'rmdir /S /Q "{os.path.realpath(path)}"')
         else:
             shutil.rmtree(path)
     except FileNotFoundError: