diff --git a/master/custom/builders.py b/master/custom/builders.py
index 3283aa75..d020b750 100644
--- a/master/custom/builders.py
+++ b/master/custom/builders.py
@@ -36,6 +36,7 @@
     Windows64BigmemBuild,
     Windows64NoGilBuild,
     Windows64PGOBuild,
+    Windows64PGONoGilBuild,
     Windows64RefleakBuild,
     Windows64ReleaseBuild,
     MacOSArmWithBrewBuild,
@@ -223,6 +224,9 @@
 
     # Windows MSVC
     ("AMD64 Windows PGO", "bolen-windows10", Windows64PGOBuild),
+
+    # Windows NoGIL
+    ("AMD64 Windows PGO NoGIL", "itamaro-win64-srv-22-aws", Windows64PGONoGilBuild),
 ]
 
 
diff --git a/master/custom/factories.py b/master/custom/factories.py
index 449c6cb4..37493ce2 100644
--- a/master/custom/factories.py
+++ b/master/custom/factories.py
@@ -680,6 +680,13 @@ class Windows64NoGilBuild(Windows64Build):
     factory_tags = ["win64", "nogil"]
 
 
+class Windows64PGONoGilBuild(Windows64PGOBuild):
+    buildersuffix = '.nogil.pgo'
+    buildFlags = Windows64PGOBuild.buildFlags + ["--disable-gil"]
+    testFlags = Windows64PGOBuild.testFlags + ["--disable-gil"]
+    factory_tags = ["win64", "nogil", "nondebug", "pgo"]
+
+
 class WindowsARM64Build(BaseWindowsBuild):
     buildFlags = ["-p", "ARM64"]
     testFlags = ["-p", "ARM64", "-j2"]