diff --git a/Lib/concurrent/interpreters/__init__.py b/Lib/concurrent/interpreters/__init__.py
index 0fd661249a276c..aa46a2b37a48d5 100644
--- a/Lib/concurrent/interpreters/__init__.py
+++ b/Lib/concurrent/interpreters/__init__.py
@@ -146,12 +146,8 @@ def __del__(self):
         self._decref()
 
     # for pickling:
-    def __getnewargs__(self):
-        return (self._id,)
-
-    # for pickling:
-    def __getstate__(self):
-        return None
+    def __reduce__(self):
+        return (type(self), (self._id,))
 
     def _decref(self):
         if not self._ownsref:
diff --git a/Lib/concurrent/interpreters/_queues.py b/Lib/concurrent/interpreters/_queues.py
index 99987f2f6926b0..9c12b2c8c24664 100644
--- a/Lib/concurrent/interpreters/_queues.py
+++ b/Lib/concurrent/interpreters/_queues.py
@@ -129,12 +129,8 @@ def __hash__(self):
         return hash(self._id)
 
     # for pickling:
-    def __getnewargs__(self):
-        return (self._id,)
-
-    # for pickling:
-    def __getstate__(self):
-        return None
+    def __reduce__(self):
+        return (type(self), (self._id,))
 
     def _set_unbound(self, op, items=None):
         assert not hasattr(self, '_unbound')
diff --git a/Lib/test/support/channels.py b/Lib/test/support/channels.py
index b2de24d9d3e534..fab1797659b312 100644
--- a/Lib/test/support/channels.py
+++ b/Lib/test/support/channels.py
@@ -105,12 +105,8 @@ def __eq__(self, other):
         return other._id == self._id
 
     # for pickling:
-    def __getnewargs__(self):
-        return (int(self._id),)
-
-    # for pickling:
-    def __getstate__(self):
-        return None
+    def __reduce__(self):
+        return (type(self), (int(self._id),))
 
     @property
     def id(self):
diff --git a/Lib/test/test_interpreters/test_api.py b/Lib/test/test_interpreters/test_api.py
index 0ee4582b5d1568..a34b20beaca7a3 100644
--- a/Lib/test/test_interpreters/test_api.py
+++ b/Lib/test/test_interpreters/test_api.py
@@ -412,9 +412,11 @@ def test_equality(self):
 
     def test_pickle(self):
         interp = interpreters.create()
-        data = pickle.dumps(interp)
-        unpickled = pickle.loads(data)
-        self.assertEqual(unpickled, interp)
+        for protocol in range(pickle.HIGHEST_PROTOCOL + 1):
+            with self.subTest(protocol=protocol):
+                data = pickle.dumps(interp, protocol)
+                unpickled = pickle.loads(data)
+                self.assertEqual(unpickled, interp)
 
 
 class TestInterpreterIsRunning(TestBase):
diff --git a/Lib/test/test_interpreters/test_channels.py b/Lib/test/test_interpreters/test_channels.py
index 109ddf344539ad..52827357078b85 100644
--- a/Lib/test/test_interpreters/test_channels.py
+++ b/Lib/test/test_interpreters/test_channels.py
@@ -121,9 +121,11 @@ def test_equality(self):
 
     def test_pickle(self):
         ch, _ = channels.create()
-        data = pickle.dumps(ch)
-        unpickled = pickle.loads(data)
-        self.assertEqual(unpickled, ch)
+        for protocol in range(pickle.HIGHEST_PROTOCOL + 1):
+            with self.subTest(protocol=protocol):
+                data = pickle.dumps(ch, protocol)
+                unpickled = pickle.loads(data)
+                self.assertEqual(unpickled, ch)
 
 
 class TestSendChannelAttrs(TestBase):
@@ -152,9 +154,11 @@ def test_equality(self):
 
     def test_pickle(self):
         _, ch = channels.create()
-        data = pickle.dumps(ch)
-        unpickled = pickle.loads(data)
-        self.assertEqual(unpickled, ch)
+        for protocol in range(pickle.HIGHEST_PROTOCOL + 1):
+            with self.subTest(protocol=protocol):
+                data = pickle.dumps(ch, protocol)
+                unpickled = pickle.loads(data)
+                self.assertEqual(unpickled, ch)
 
 
 class TestSendRecv(TestBase):
diff --git a/Lib/test/test_interpreters/test_queues.py b/Lib/test/test_interpreters/test_queues.py
index cb17340f581b0a..5451c6654acb47 100644
--- a/Lib/test/test_interpreters/test_queues.py
+++ b/Lib/test/test_interpreters/test_queues.py
@@ -188,9 +188,11 @@ def test_equality(self):
 
     def test_pickle(self):
         queue = queues.create()
-        data = pickle.dumps(queue)
-        unpickled = pickle.loads(data)
-        self.assertEqual(unpickled, queue)
+        for protocol in range(pickle.HIGHEST_PROTOCOL + 1):
+            with self.subTest(protocol=protocol):
+                data = pickle.dumps(queue, protocol)
+                unpickled = pickle.loads(data)
+                self.assertEqual(unpickled, queue)
 
 
 class TestQueueOps(TestBase):
diff --git a/Misc/NEWS.d/next/Library/2025-07-05-09-45-04.gh-issue-136286.N67Amr.rst b/Misc/NEWS.d/next/Library/2025-07-05-09-45-04.gh-issue-136286.N67Amr.rst
new file mode 100644
index 00000000000000..0a0d66ac0b8abf
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2025-07-05-09-45-04.gh-issue-136286.N67Amr.rst
@@ -0,0 +1,2 @@
+Fix pickling failures for protocols 0 and 1 for many objects realted to
+subinterpreters.