From 6785219c115d353a74a3cdd98bd41678033e103a Mon Sep 17 00:00:00 2001 From: Jim McCusker Date: Fri, 24 Apr 2020 17:51:54 -0400 Subject: [PATCH] Modified to fix URIs that have backslashes in them to be direct URLs to their sources. --- clinical_measurement.obo | 1378 +++++++++++++++++++------------------- 1 file changed, 689 insertions(+), 689 deletions(-) diff --git a/clinical_measurement.obo b/clinical_measurement.obo index 0963f5b..f2855cb 100644 --- a/clinical_measurement.obo +++ b/clinical_measurement.obo @@ -139,7 +139,7 @@ creation_date: 2010-06-18T09:49:01Z [Term] id: CMO:0000020 name: waist to hip ratio (WHR) -def: "The circumference of the body at the level of the navel divided by the circumference at the widest point around the buttock, often used to assess distribution of sub-cutaneous and intra-abdominal adipose tissue." [Wikipedia:http\://en.wikipedia.org/wiki/Waist-hip_ratio] +def: "The circumference of the body at the level of the navel divided by the circumference at the widest point around the buttock, often used to assess distribution of sub-cutaneous and intra-abdominal adipose tissue." [https://en.wikipedia.org/wiki/Waist-hip_ratio] synonym: "waist/hip ratio" RELATED [] is_a: CMO:0000022 ! calculated body morphological measurement created_by: mshimoyama @@ -186,7 +186,7 @@ is_a: CMO:0003102 ! red blood cell morphological measurement [Term] id: CMO:0000026 name: blood hemoglobin level -def: "The amount of hemoglobin in a specific volume of blood, expressed as grams per deciliter of whole blood in humans." [MedicineNet:http\://www.medicinenet.com] +def: "The amount of hemoglobin in a specific volume of blood, expressed as grams per deciliter of whole blood in humans." [http://www.medicinenet.com] synonym: "blood haemoglobin level" EXACT [] is_a: CMO:0000028 ! blood protein measurement @@ -255,7 +255,7 @@ is_a: CMO:0000000 ! clinical measurement [Term] id: CMO:0000036 name: complete blood count and differential -def: "A value resulting from the quantification of the cellular elements of the blood, including morphological or physiological parameter of blood cells, i.e. cells native to the circulation, including those of erythroid, lymphoid, myeloid and monocytic lineages. A cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A value resulting from the quantification of the cellular elements of the blood, including morphological or physiological parameter of blood cells, i.e. cells native to the circulation, including those of erythroid, lymphoid, myeloid and monocytic lineages. A cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, http://www.thefreedictionary.com/] synonym: "CBC" RELATED [] synonym: "CBC blood test" EXACT [] synonym: "CBC, differential" EXACT [] @@ -299,20 +299,20 @@ creation_date: 2009-12-17T10:47:50Z [Term] id: CMO:0000041 name: red blood cell distribution width-coefficient of variation -def: "The red cell distribution width (RDW) is a measurement derived from the red blood cell distribution curves generated on automated hematology analyzers and is an indicator of variation in RBC size within a blood sample. The RDW is used along with the indices (MCV, MCH, MCHC) to describe a population of RBCs. The RDW measures the deviation of the RBC width, not the actual width or size of individual cells. The RDW-CV is a calculation based on both the width of the distribution curve and the mean cell size. It is calculated by dividing the standard deviation of the mean cell size by the MCV of the red cells and multiplying by 100 to convert to a percentage." [LabCE:https\://www.labce.com/spg579122_red_blood_cell_distribution_width_rdw_definition_a.aspx, Wikipedia:http\://en.wikipedia.org] +def: "The red cell distribution width (RDW) is a measurement derived from the red blood cell distribution curves generated on automated hematology analyzers and is an indicator of variation in RBC size within a blood sample. The RDW is used along with the indices (MCV, MCH, MCHC) to describe a population of RBCs. The RDW measures the deviation of the RBC width, not the actual width or size of individual cells. The RDW-CV is a calculation based on both the width of the distribution curve and the mean cell size. It is calculated by dividing the standard deviation of the mean cell size by the MCV of the red cells and multiplying by 100 to convert to a percentage." [https://www.labce.com/spg579122_red_blood_cell_distribution_width_rdw_definition_a.aspx, https://en.wikipedia.org] synonym: "RDW" RELATED [] is_a: CMO:0003102 ! red blood cell morphological measurement [Term] id: CMO:0000042 name: plasma glucose level -def: "Measurement of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [http://www.thefreedictionary.com/] is_a: CMO:0000046 ! blood glucose level [Term] id: CMO:0000043 name: plasma aspartate aminotransferase activity level -def: "The amount of enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of plasma. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Plasma AST level is used as an enzymatic marker for liver disease or damage." [VT:0000203, Wikipedia:http\://en.wikipedia.org/wiki/Aspartate_transaminase] +def: "The amount of enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of plasma. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Plasma AST level is used as an enzymatic marker for liver disease or damage." [VT:0000203, https://en.wikipedia.org/wiki/Aspartate_transaminase] synonym: "plasma aspartate transaminase activity level" EXACT [] synonym: "plasma AST activity level" RELATED [] synonym: "plasma glutamic-oxaloacetic transaminase activity level" EXACT [] @@ -322,7 +322,7 @@ is_a: CMO:0000580 ! blood aspartate aminotransferase activity level [Term] id: CMO:0000044 name: plasma alanine aminotransferase activity level -def: "The amount of ezymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of plasma. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Plasma ALT activity level is used as an enzymatic marker for liver disease or damage." [RGD:737472, Wikipedia:http\://en.wikipedia.org/wiki/Creatine_kinase] +def: "The amount of ezymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of plasma. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Plasma ALT activity level is used as an enzymatic marker for liver disease or damage." [RGD:737472, https://en.wikipedia.org/wiki/Creatine_kinase] synonym: "plasma alanine transaminase activity level" EXACT [] synonym: "plasma ALT activity level" RELATED [] synonym: "plasma glutamic-pyruvate transaminase activity level" EXACT [] @@ -338,7 +338,7 @@ is_a: CMO:0000576 ! blood alkaline phosphatase activity level [Term] id: CMO:0000046 name: blood glucose level -def: "Measurement of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [http://www.thefreedictionary.com/] is_a: CMO:0000023 ! blood chemistry measurement relationship: part_of CMO:0003099 ! comprehensive metabolic panel created_by: mshimoyama @@ -383,7 +383,7 @@ is_a: CMO:0002280 ! blood cholesterol level [Term] id: CMO:0000052 name: blood high density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in high-density lipoprotein (HDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in high-density lipoprotein (HDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "blood HDL-C" RELATED [] synonym: "blood HDL level" RELATED [] @@ -392,7 +392,7 @@ is_a: CMO:0002696 ! blood lipoprotein cholesterol level [Term] id: CMO:0000053 name: blood low density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in low-density lipoprotein (LDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [BioMedCentral:http\://www.biomedcentral.com/1746-6148/9/47, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in low-density lipoprotein (LDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [http://www.biomedcentral.com/1746-6148/9/47, http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "blood LDL-C level" RELATED [] synonym: "blood LDL level" RELATED [] @@ -727,7 +727,7 @@ is_a: CMO:0000098 ! lung dry weight [Term] id: CMO:0000105 name: body mass index (BMI) -def: "A measurement relating body weight to height in an organism; typically calculated as the weight of an individual divided by the height of that individual squared. For quadrupeds, the square of body height is often replaced by the square of body length." [MedicineNet:http\://www.medicinenet.com] +def: "A measurement relating body weight to height in an organism; typically calculated as the weight of an individual divided by the height of that individual squared. For quadrupeds, the square of body height is often replaced by the square of body length." [http://www.medicinenet.com] synonym: "BMI" RELATED [] is_a: CMO:0001196 ! calculated body weight measurement @@ -859,7 +859,7 @@ creation_date: 2009-12-17T10:25:02Z [Term] id: CMO:0000121 name: blood angiotensin II level -def: "The amount of angiotensin II in a specific sample of blood. Angiotensin II (AngII) is the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion." [Wikipedia:http\://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II] +def: "The amount of angiotensin II in a specific sample of blood. Angiotensin II (AngII) is the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion." [https://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II] synonym: "blood AngII level" RELATED [] is_a: CMO:0000286 ! blood peptide hormone level created_by: mshimoyama @@ -868,7 +868,7 @@ creation_date: 2009-12-17T10:28:12Z [Term] id: CMO:0000122 name: mean corpuscular hemoglobin level -def: "The average amount of hemoglobin per red blood cell as a caculated value by dividing the total mass of hemoglobin by the number of red blood cells in a volume of blood, often expressed as picograms per cell." [Wikipedia:http\://en.wikipedia.org/wiki/Mean_corpuscular_hemoglobin] +def: "The average amount of hemoglobin per red blood cell as a caculated value by dividing the total mass of hemoglobin by the number of red blood cells in a volume of blood, often expressed as picograms per cell." [https://en.wikipedia.org/wiki/Mean_corpuscular_hemoglobin] is_obsolete: true created_by: mshimoyama creation_date: 2009-12-17T10:32:27Z @@ -960,7 +960,7 @@ creation_date: 2009-12-17T11:12:05Z [Term] id: CMO:0000133 name: end-tidal partial pressure of carbon dioxide (PETCO2) -def: "The amount of carbon dioxide present in air exhaled from the lungs." [Wikipedia:http\://en.wikipedia.org] +def: "The amount of carbon dioxide present in air exhaled from the lungs." [https://en.wikipedia.org] is_a: CMO:0000094 ! respiratory system measurement created_by: mshimoyama creation_date: 2009-12-17T11:13:29Z @@ -976,7 +976,7 @@ creation_date: 2009-12-17T11:13:53Z [Term] id: CMO:0000135 name: maximal oxygen consumption -def: "Maximum capacity of an individual's body to transport and utilize oxygen, usually measured during exercise as volume of oxygen per unit of time." [Wikipedia:http\://en.wikipedia.org/wiki/VO2_max] +def: "Maximum capacity of an individual's body to transport and utilize oxygen, usually measured during exercise as volume of oxygen per unit of time." [https://en.wikipedia.org/wiki/VO2_max] synonym: "maximal aerobic capacity" RELATED [] synonym: "maximal oxygen uptake" RELATED [] synonym: "peak oxygen uptake" RELATED [] @@ -1042,7 +1042,7 @@ creation_date: 2010-05-17T01:50:12Z [Term] id: CMO:0000142 name: adrenal gland morphological measurement -def: "Measurement of the physical form or structure of one or both of the adrenal glands, the complex endocrine glands located just above the kidneys which release hormones in response to stress through the synthesis of corticosteroids such as cortisol and catecholamines such as adrenaline (epinephrine) and noradrenaline, as well as producing androgens in the innermost cortical layer." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Adrenal_Gland] +def: "Measurement of the physical form or structure of one or both of the adrenal glands, the complex endocrine glands located just above the kidneys which release hormones in response to stress through the synthesis of corticosteroids such as cortisol and catecholamines such as adrenaline (epinephrine) and noradrenaline, as well as producing androgens in the innermost cortical layer." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Adrenal_Gland] synonym: "suprarenal gland morphological measurement" RELATED [] is_a: CMO:0000068 ! organ morphological measurement created_by: RNigam @@ -1397,7 +1397,7 @@ creation_date: 2010-06-10T09:12:29Z [Term] id: CMO:0000184 name: skull volume -def: "Total volume or capacity of the bony or cartilaginous framework of the head." [Wikipedia:http\://en.wikipedia.org] +def: "Total volume or capacity of the bony or cartilaginous framework of the head." [https://en.wikipedia.org] is_a: CMO:0000182 ! head morphological measurement created_by: mshimoyama creation_date: 2010-06-10T09:12:47Z @@ -1413,7 +1413,7 @@ creation_date: 2010-06-10T09:27:49Z [Term] id: CMO:0000186 name: distal hind limb circumference -def: "The linear distance around the lower portion of the hind limb, i.e. the segment of the hind limb farthest from the body." [RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Circumference] +def: "The linear distance around the lower portion of the hind limb, i.e. the segment of the hind limb farthest from the body." [RGD:JRS, https://en.wikipedia.org/wiki/Circumference] synonym: "distal back leg circumference" RELATED [] synonym: "distal hind leg circumference" RELATED [] is_a: CMO:0000388 ! hind limb morphological measurement @@ -1471,7 +1471,7 @@ creation_date: 2010-06-10T09:31:33Z [Term] id: CMO:0000193 name: intramuscular fat weight -def: "A measurement of the amount, by weight, of the small deposits of fat located within a specified amount of skeletal muscle." [Wikipedia:http\://en.wikipedia.org/wiki/Intramuscular_fat] +def: "A measurement of the amount, by weight, of the small deposits of fat located within a specified amount of skeletal muscle." [https://en.wikipedia.org/wiki/Intramuscular_fat] synonym: "intramuscular adipose tissue weight" RELATED [] synonym: "intramuscular adipose weight" RELATED [] is_a: CMO:0000208 ! intramuscular fat morphological measurement @@ -1481,7 +1481,7 @@ creation_date: 2010-06-24T01:24:38Z [Term] id: CMO:0000194 name: blood viscoelasticity -def: "A measurement to describe the combined properties of viscosity, related to the energy dissipated during flow, and elasticity, related to the energy stored during flow, of blood." [Vilastic:http\://www.vilastic.com] +def: "A measurement to describe the combined properties of viscosity, related to the energy dissipated during flow, and elasticity, related to the energy stored during flow, of blood." [http://www.vilastic.com] is_a: CMO:0000035 ! blood measurement created_by: mshimoyama creation_date: 2010-06-10T09:34:10Z @@ -1530,7 +1530,7 @@ creation_date: 2010-06-10T09:56:38Z [Term] id: CMO:0000200 name: intramuscular fat weight as percent of body weight -def: "A calculated measurement in which the weight of the small deposits of fat located within and throughout skeletal muscle is presented as a percentage of the total weight of the body thus normalizing it to body weight." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Intramuscular_fat] +def: "A calculated measurement in which the weight of the small deposits of fat located within and throughout skeletal muscle is presented as a percentage of the total weight of the body thus normalizing it to body weight." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, https://en.wikipedia.org/wiki/Intramuscular_fat] synonym: "intramuscular adipose weight as percent of body weight" RELATED [] is_a: CMO:0001164 ! calculated intramuscular fat weight created_by: mshimoyama @@ -1585,7 +1585,7 @@ creation_date: 2010-06-10T11:01:19Z [Term] id: CMO:0000207 name: bleeding time (BT) -def: "The time interval between the appearance of the first drop of blood and the removal of the last drop after puncture. In humans, the puncture is often made in the ear lobe or finger." [MediLexicon:http\://www.medilexicon.com] +def: "The time interval between the appearance of the first drop of blood and the removal of the last drop after puncture. In humans, the puncture is often made in the ear lobe or finger." [http://www.medilexicon.com] is_a: CMO:0000205 ! in vivo coagulation measurement created_by: mshimoyama creation_date: 2010-06-10T11:04:59Z @@ -1593,7 +1593,7 @@ creation_date: 2010-06-10T11:04:59Z [Term] id: CMO:0000208 name: intramuscular fat morphological measurement -def: "Measurement of the physical form or structure of the small deposits of fat located within and throughout skeletal muscle." [Wikipedia:http\://en.wikipedia.org/wiki/Intramuscular_fat] +def: "Measurement of the physical form or structure of the small deposits of fat located within and throughout skeletal muscle." [https://en.wikipedia.org/wiki/Intramuscular_fat] is_a: CMO:0000089 ! body fat morphological measurement is_a: CMO:0001147 ! skeletal muscle morphological measurement created_by: mshimoyama @@ -1602,7 +1602,7 @@ creation_date: 2010-06-24T01:25:42Z [Term] id: CMO:0000209 name: blood fibrinogen level -def: "Measurement of the amount of fibrinogen in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Fibrinogen is a glycoprotein comprised of three pairs of nonidentical polypeptide chains; cleavage products of fibrinogen have a major role in blood clotting as well as roles in cell adhesion and spreading, display vasoconstrictor activity, and can function as chemotactic and mitogenic agents for several cell types." [RGD:737209, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Fibrinogen] +def: "Measurement of the amount of fibrinogen in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Fibrinogen is a glycoprotein comprised of three pairs of nonidentical polypeptide chains; cleavage products of fibrinogen have a major role in blood clotting as well as roles in cell adhesion and spreading, display vasoconstrictor activity, and can function as chemotactic and mitogenic agents for several cell types." [RGD:737209, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Fibrinogen] synonym: "Factor I level" RELATED [] is_a: CMO:0000028 ! blood protein measurement is_a: CMO:0000206 ! in vitro coagulation measurement @@ -1612,7 +1612,7 @@ creation_date: 2010-06-10T11:07:51Z [Term] id: CMO:0000210 name: activated partial thromboplastin time -def: "The time needed for plasma to form a fibrin clot after the addition of calcium and a phospholipid reagent. It is used to evaluate the intrinsic clotting system." [MediLexicon:http\://www.medilexicon.com] +def: "The time needed for plasma to form a fibrin clot after the addition of calcium and a phospholipid reagent. It is used to evaluate the intrinsic clotting system." [http://www.medilexicon.com] is_a: CMO:0000206 ! in vitro coagulation measurement created_by: mshimoyama creation_date: 2010-06-10T11:20:31Z @@ -1628,7 +1628,7 @@ creation_date: 2010-06-10T11:21:04Z [Term] id: CMO:0000212 name: thrombin time -def: "The time needed for a fibrin clot to form after the addition of thrombin to citrated plasma." [MediLexicon:http\://www.medilexicon.com] +def: "The time needed for a fibrin clot to form after the addition of thrombin to citrated plasma." [http://www.medilexicon.com] is_a: CMO:0000206 ! in vitro coagulation measurement created_by: mshimoyama creation_date: 2010-06-10T11:21:44Z @@ -1744,7 +1744,7 @@ creation_date: 2010-06-25T10:29:56Z [Term] id: CMO:0000226 name: body fat percentage, Lukaski equation -def: "Total body fat as a percentage of total body mass calculated based on Total Body Water equal to 0.372 times height in centimeters squared divided by resistance plus 3.05 times sex (male-1, female-2) plus 0.142 times weight minus 0.69 times age." [RGD:MS, Website:http\://www.brianmac.co.uk/fatbia.htm] +def: "Total body fat as a percentage of total body mass calculated based on Total Body Water equal to 0.372 times height in centimeters squared divided by resistance plus 3.05 times sex (male-1, female-2) plus 0.142 times weight minus 0.69 times age." [RGD:MS, http://www.brianmac.co.uk/fatbia.htm] is_a: CMO:0000302 ! body fat percentage created_by: mshimoyama creation_date: 2010-06-16T10:58:12Z @@ -1798,7 +1798,7 @@ creation_date: 2010-06-17T10:37:24Z [Term] id: CMO:0000232 name: RR interval -def: "Interval between an R wave and the next R wave of successive heart beats, inverse of the heart rate." [RGD:MS, Wikipedia:http\://en.wikipedia.org/wiki/ECG] +def: "Interval between an R wave and the next R wave of successive heart beats, inverse of the heart rate." [RGD:MS, https://en.wikipedia.org/wiki/ECG] synonym: "RR_Interval" RELATED [ECGOntology: "ECG_000000042"] is_a: CMO:0000230 ! heart electrical conduction measurement created_by: mshimoyama @@ -1807,7 +1807,7 @@ creation_date: 2010-06-17T10:39:30Z [Term] id: CMO:0000233 name: PR interval -def: "Time between the beginning of the P wave to the beginning of the QRS complex, reflects the time the electrical impulse takes to travel from the sinus node through the AVE node and entering the ventricles, used as an estimate of AV node function." [Wikipedia:http\://en.wikipedia.org/wiki/ECG] +def: "Time between the beginning of the P wave to the beginning of the QRS complex, reflects the time the electrical impulse takes to travel from the sinus node through the AVE node and entering the ventricles, used as an estimate of AV node function." [https://en.wikipedia.org/wiki/ECG] synonym: "PR_Interval" RELATED [ECGOntology: "ECG_0000003541"] is_a: CMO:0000230 ! heart electrical conduction measurement created_by: mshimoyama @@ -1816,7 +1816,7 @@ creation_date: 2010-06-17T10:40:52Z [Term] id: CMO:0000234 name: ST interval -def: "The time between the J point ( the point at which the QRS complex finishes and the ST segment begins) to the end of the T wave." [Wikipedia:http\://en.wikipedia.org/wiki/ECG] +def: "The time between the J point ( the point at which the QRS complex finishes and the ST segment begins) to the end of the T wave." [https://en.wikipedia.org/wiki/ECG] synonym: "ST_Interval" RELATED [ECGOntology: "ECG_000000824"] is_a: CMO:0000230 ! heart electrical conduction measurement created_by: mshimoyama @@ -1825,7 +1825,7 @@ creation_date: 2010-06-17T10:43:21Z [Term] id: CMO:0000235 name: QT interval -def: "An interval measured from the onset of the QRS wave complex to the offset of the T wave." [RGD:MS, Wikipedia:http\://en.wikipedia.org/wiki/ECG] +def: "An interval measured from the onset of the QRS wave complex to the offset of the T wave." [RGD:MS, https://en.wikipedia.org/wiki/ECG] synonym: "QT_Interval" RELATED [ECGOntology: "ECG_000000682"] is_a: CMO:0000230 ! heart electrical conduction measurement created_by: mshimoyama @@ -1860,7 +1860,7 @@ creation_date: 2010-06-17T11:13:15Z [Term] id: CMO:0000239 name: heart left ventricle posterior wall thickness -def: "The thickness or depth (i.e. the measurement of the two-dimensional extent of the distance between the inner and outer surfaces) of the dorsal/posterior wall of the left ventricle of the heart. The dorsal wall is the portion of the muscle enclosing the ventricle which is closest to the spine and farthest from the chest wall of the organism. The left ventricle is the lower chamber of the left side of the heart, which pumps oxygenated blood out through the aorta to all the tissues of the body." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PGA:Ultrasound_protocol, RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location)] +def: "The thickness or depth (i.e. the measurement of the two-dimensional extent of the distance between the inner and outer surfaces) of the dorsal/posterior wall of the left ventricle of the heart. The dorsal wall is the portion of the muscle enclosing the ventricle which is closest to the spine and farthest from the chest wall of the organism. The left ventricle is the lower chamber of the left side of the heart, which pumps oxygenated blood out through the aorta to all the tissues of the body." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PGA:Ultrasound_protocol, RGD:JRS, https://en.wikipedia.org/wiki/Anatomical_terms_of_location)] comment: Note that "left" in this context refers to the perspective of the organism, not that of the observer. synonym: "heart left ventricle dorsal wall thickness" RELATED [] is_a: CMO:0000238 ! heart posterior wall thickness @@ -1881,7 +1881,7 @@ creation_date: 2010-06-17T11:15:42Z [Term] id: CMO:0000241 name: forced expiratory volume to forced vital capacity ratio -def: "The comparison of forced expiratory volume to forced vital capacity expressed as ratio or percentage." [Wikipedia:http\://en.wikipedia.org] +def: "The comparison of forced expiratory volume to forced vital capacity expressed as ratio or percentage." [https://en.wikipedia.org] is_a: CMO:0000094 ! respiratory system measurement created_by: mshimoyama creation_date: 2010-12-16T01:02:33Z @@ -2112,7 +2112,7 @@ creation_date: 2010-06-17T12:40:30Z [Term] id: CMO:0000269 name: QTC interval -def: "QT interval corrected for heart rate calculated by the QT interval divided by the square root of the interval from one QRS complex to the onset of the next QRS complex measured in seconds." [Wikipedia:http\://en.wikipedia.org] +def: "QT interval corrected for heart rate calculated by the QT interval divided by the square root of the interval from one QRS complex to the onset of the next QRS complex measured in seconds." [https://en.wikipedia.org] is_a: CMO:0000230 ! heart electrical conduction measurement created_by: mshimoyama creation_date: 2010-06-17T12:40:52Z @@ -2181,7 +2181,7 @@ creation_date: 2010-06-17T12:43:21Z [Term] id: CMO:0000278 name: PP interval -def: "An interval measured from the onset of the P wave in one PQRST wave complex to the onset of the P wave in the following PQRST wave complex." [Wikipedia:http\://en.wikipedia.org/wiki/ECG] +def: "An interval measured from the onset of the P wave in one PQRST wave complex to the onset of the P wave in the following PQRST wave complex." [https://en.wikipedia.org/wiki/ECG] synonym: "PP_Interval" RELATED [ECGOntology: "ECG_000000011"] is_a: CMO:0000230 ! heart electrical conduction measurement created_by: mshimoyama @@ -2205,7 +2205,7 @@ creation_date: 2010-06-17T03:41:36Z [Term] id: CMO:0000281 name: urine calcium level -def: "The amount of calcium in a specified volume of urine. Usually determined from a 24 hour volume of urine, expressed in mg of urine per kg of calcium per day or mg per 24 hours." [Medline_Plus:http\://www.nlm.nih.gov/medlineplus/] +def: "The amount of calcium in a specified volume of urine. Usually determined from a 24 hour volume of urine, expressed in mg of urine per kg of calcium per day or mg per 24 hours." [http://www.nlm.nih.gov/medlineplus/] is_a: CMO:0000593 ! urine electrolyte level created_by: mshimoyama creation_date: 2010-06-17T03:42:07Z @@ -2287,7 +2287,7 @@ creation_date: 2011-09-21T11:30:32Z id: CMO:0000290 name: mean corpuscular hemoglobin level alt_id: CMO:0000122 -def: "The average amount of hemoglobin per red blood cell caculated by dividing the total mass of hemoglobin by the number of red blood cells in a volume of blood." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Mean_corpuscular_hemoglobin] +def: "The average amount of hemoglobin per red blood cell caculated by dividing the total mass of hemoglobin by the number of red blood cells in a volume of blood." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, https://en.wikipedia.org/wiki/Mean_corpuscular_hemoglobin] synonym: "MCH" RELATED [] synonym: "mean corpuscular haemoglobin level" EXACT [] is_a: CMO:0000026 ! blood hemoglobin level @@ -2298,7 +2298,7 @@ creation_date: 2010-06-25T01:31:46Z [Term] id: CMO:0000291 name: mean corpuscular hemoglobin concentration -def: "The amount of hemoglobin in a given volume of packed red blood cells and is often calculated by dividing the hemoglobin concentration by the hematocrit." [Wikipedia:http\://en.wikipedia.org] +def: "The amount of hemoglobin in a given volume of packed red blood cells and is often calculated by dividing the hemoglobin concentration by the hematocrit." [https://en.wikipedia.org] synonym: "MCHC" RELATED [] synonym: "mean corpuscular haemoglobin concentration" EXACT [] is_a: CMO:0003102 ! red blood cell morphological measurement @@ -2324,7 +2324,7 @@ creation_date: 2010-08-04T09:43:03Z [Term] id: CMO:0000294 name: pulse -def: "The count of the rhythmic contractions and expansions of an artery due to the surge of blood from the beat of the heart." [MedicineNet:http\://www.medicinenet.com] +def: "The count of the rhythmic contractions and expansions of an artery due to the surge of blood from the beat of the heart." [http://www.medicinenet.com] is_a: CMO:0000001 ! cardiovascular measurement created_by: mshimoyama creation_date: 2010-08-04T10:37:40Z @@ -2332,7 +2332,7 @@ creation_date: 2010-08-04T10:37:40Z [Term] id: CMO:0000295 name: upright sagittal abdominal diameter -def: "The measured distance from an individual's back to upper abdomen from midway between the top of the pelvis and the bottom of the ribs, commonly measured while the individual is upright." [Wikipedia:http\://en.wikipedia.org/wiki/Sagittal_Abdominal_Diameter] +def: "The measured distance from an individual's back to upper abdomen from midway between the top of the pelvis and the bottom of the ribs, commonly measured while the individual is upright." [https://en.wikipedia.org/wiki/Sagittal_Abdominal_Diameter] is_a: CMO:0000296 ! abdominal morphological measurement created_by: mshimoyama creation_date: 2010-08-04T01:46:40Z @@ -2347,7 +2347,7 @@ creation_date: 2010-08-04T01:50:13Z [Term] id: CMO:0000297 name: supine abdominal height -def: "Measured distance between back and upper abdomen of an individual, midway between the top of the pelvis and bottom of the ribs while individual is in the supine position." [Wikipedia:http\://en.wikipedia.org] +def: "Measured distance between back and upper abdomen of an individual, midway between the top of the pelvis and bottom of the ribs while individual is in the supine position." [https://en.wikipedia.org] is_a: CMO:0000296 ! abdominal morphological measurement created_by: mshimoyama creation_date: 2010-08-04T01:51:04Z @@ -2382,7 +2382,7 @@ creation_date: 2011-09-21T01:19:42Z [Term] id: CMO:0000301 name: body density -def: "The measure of mass per unit of volume often used to determine body fat composition. Techniques often used include comparison of body weight inside and outside of water or a ratio of body volume and weight. Common formulas include body density equal to body weight divided by body volume minus residual lung volume or body density equal to body weight divided by the dividend of body weight minus water weight divided by the density of water minus residual lung volume." [Encyclopedia.com:http\://www.encyclopedia.com] +def: "The measure of mass per unit of volume often used to determine body fat composition. Techniques often used include comparison of body weight inside and outside of water or a ratio of body volume and weight. Common formulas include body density equal to body weight divided by body volume minus residual lung volume or body density equal to body weight divided by the dividend of body weight minus water weight divided by the density of water minus residual lung volume." [http://www.encyclopedia.com] is_a: CMO:0000089 ! body fat morphological measurement created_by: mshimoyama creation_date: 2010-08-04T02:17:57Z @@ -2397,7 +2397,7 @@ creation_date: 2010-08-05T08:53:40Z [Term] id: CMO:0000303 name: body fat percentage, Siri equation -def: "Total body fat expressed as a percentage of body mass using the formula percent body fat equals 495 divided by body density minus 450. Often used for Caucasian men." [TopEndSports:http\://www.topendsports.com] +def: "Total body fat expressed as a percentage of body mass using the formula percent body fat equals 495 divided by body density minus 450. Often used for Caucasian men." [http://www.topendsports.com] is_a: CMO:0000302 ! body fat percentage created_by: mshimoyama creation_date: 2010-08-05T08:54:02Z @@ -2781,7 +2781,7 @@ creation_date: 2010-11-08T01:45:04Z [Term] id: CMO:0000350 name: blood glucose level area under curve (AUC) -def: "A calculated value in which a series of measurements of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Mondofacto:Mondofacto_Online_Medical_Dictionary, Wikipedia:http\://en.wikipedia.org/wiki/Area_under_curve] +def: "A calculated value in which a series of measurements of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Mondofacto:Mondofacto_Online_Medical_Dictionary, https://en.wikipedia.org/wiki/Area_under_curve] synonym: "AUC glucose" RELATED [] is_a: CMO:0000352 ! calculated blood glucose level created_by: mshimoyama @@ -2790,7 +2790,7 @@ creation_date: 2010-11-08T03:31:06Z [Term] id: CMO:0000351 name: blood insulin level area under curve (AUC) -def: "A calculated value in which a series of measurements of the amount of insulin in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined. Insulin is the fuel-regulating peptide hormone which is formed from proinsulin in the beta cells of the pancreatic islets and which promotes the storage of glucose and the uptake of amino acids, increases protein and lipid synthesis, and inhibits lipolysis and gluconeogenesis." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Area_under_curve] +def: "A calculated value in which a series of measurements of the amount of insulin in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined. Insulin is the fuel-regulating peptide hormone which is formed from proinsulin in the beta cells of the pancreatic islets and which promotes the storage of glucose and the uptake of amino acids, increases protein and lipid synthesis, and inhibits lipolysis and gluconeogenesis." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Area_under_curve] synonym: "blood insulin AUC" RELATED [] is_a: CMO:0000353 ! calculated blood insulin level created_by: mshimoyama @@ -2799,7 +2799,7 @@ creation_date: 2010-11-08T03:54:32Z [Term] id: CMO:0000352 name: calculated blood glucose level -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [http://www.thefreedictionary.com/] is_a: CMO:0000046 ! blood glucose level created_by: mshimoyama creation_date: 2010-11-09T09:35:22Z @@ -2871,7 +2871,7 @@ creation_date: 2010-11-12T09:44:31Z [Term] id: CMO:0000361 name: serum high density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in high-density lipoprotein (HDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in high-density lipoprotein (HDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "serum HDL-C level" RELATED [] synonym: "serum HDL level" RELATED [] @@ -2883,7 +2883,7 @@ creation_date: 2010-11-12T09:46:16Z [Term] id: CMO:0000362 name: serum low density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in low-density lipoprotein (LDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [BioMedCentral:http\://www.biomedcentral.com/1746-6148/9/47, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in low-density lipoprotein (LDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [http://www.biomedcentral.com/1746-6148/9/47, http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "serum LDL-C level" RELATED [] synonym: "serum LDL level" RELATED [] @@ -3143,7 +3143,7 @@ creation_date: 2010-12-17T01:05:23Z [Term] id: CMO:0000388 name: hind limb morphological measurement -def: "Measurement of the physical form or structure of a posterior appendage such as a leg or the homologous structure in other animals. In quadrupeds, the appendage(s) farthest from the head of the animal." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dictionary.com:http\://dictionary.reference.com/browse/hindlimb?r=66] +def: "Measurement of the physical form or structure of a posterior appendage such as a leg or the homologous structure in other animals. In quadrupeds, the appendage(s) farthest from the head of the animal." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, http://dictionary.reference.com/browse/hindlimb?r=66] synonym: "back leg morphological measurement" RELATED [] synonym: "hind leg morphological measurement" RELATED [] is_a: CMO:0000185 ! limb morphological measurement @@ -3439,7 +3439,7 @@ creation_date: 2010-12-29T09:35:05Z [Term] id: CMO:0000426 name: consumption measurement -def: "The quantification of any morphological or physiological parameter related to intake or ingestion, especially of food or drink, or a value resulting from such a quantification." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Consumption] +def: "The quantification of any morphological or physiological parameter related to intake or ingestion, especially of food or drink, or a value resulting from such a quantification." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, https://en.wikipedia.org/wiki/Consumption] is_a: CMO:0000000 ! clinical measurement created_by: mshimoyama creation_date: 2010-12-29T09:44:29Z @@ -3680,7 +3680,7 @@ creation_date: 2010-12-29T03:15:35Z [Term] id: CMO:0000455 name: drink intake rate -def: "Amount of drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed per unit time." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, YourDictionary:http\://www.yourdictionary.com/drink] +def: "Amount of drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed per unit time." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.yourdictionary.com/drink] is_a: CMO:0000771 ! drink intake measurement created_by: mshimoyama creation_date: 2010-12-29T03:16:47Z @@ -3972,7 +3972,7 @@ creation_date: 2011-01-04T12:06:48Z [Term] id: CMO:0000490 name: blood glomerular filtration rate -def: "An estimation of the volume of blood filtered from the kidney glomerular capillaries into the Bowman's capsule per specified unit of time based on serum creatinine level, wieght and age of organism and other factors." [Wikipedia:http\://en.wikipedia.org] +def: "An estimation of the volume of blood filtered from the kidney glomerular capillaries into the Bowman's capsule per specified unit of time based on serum creatinine level, wieght and age of organism and other factors." [https://en.wikipedia.org] is_a: CMO:0000023 ! blood chemistry measurement is_a: CMO:0000906 ! kidney measurement created_by: mshimoyama @@ -4061,7 +4061,7 @@ creation_date: 2011-01-04T02:56:30Z [Term] id: CMO:0000501 name: blood uric acid level -def: "The amount of uric acid, a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen,the end product of purine catabolism, in a specified sample of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org] +def: "The amount of uric acid, a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen,the end product of purine catabolism, in a specified sample of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org] is_a: CMO:0000023 ! blood chemistry measurement created_by: mshimoyama creation_date: 2011-01-04T03:05:36Z @@ -4318,7 +4318,7 @@ creation_date: 2011-10-28T04:22:41Z [Term] id: CMO:0000533 name: absolute change in mean arterial blood pressure -def: "The difference in mean arterial blood pressure between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, RGD:MS, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in mean arterial blood pressure between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, RGD:MS, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0000009 ! mean arterial blood pressure is_a: CMO:0000743 ! change in calculated blood pressure @@ -4405,7 +4405,7 @@ creation_date: 2011-11-02T02:44:01Z [Term] id: CMO:0000543 name: serum glucose level -def: "Measurement of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of the amount of glucose, the monosaccharide sugar, C6H12O6, occurring widely in plant and animal tissues which is one of the three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is the end product of carbohydrate metabolism, and is the chief source of energy for living organisms, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [http://www.thefreedictionary.com/] is_a: CMO:0000046 ! blood glucose level created_by: mshimoyama creation_date: 2011-11-02T02:45:05Z @@ -4599,7 +4599,7 @@ creation_date: 2011-11-02T04:07:40Z [Term] id: CMO:0000570 name: plasma ethanol level -def: "The amount of ethanol, the colorless, volatile, flammable liquid, CH3CH2OH, produced by yeast fermentation of carbohydrates or synthesized by hydration of ethylene, found in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "The amount of ethanol, the colorless, volatile, flammable liquid, CH3CH2OH, produced by yeast fermentation of carbohydrates or synthesized by hydration of ethylene, found in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [http://www.thefreedictionary.com/] synonym: "plasma alcohol level" RELATED [] is_a: CMO:0000535 ! blood ethanol level created_by: mshimoyama @@ -4635,7 +4635,7 @@ creation_date: 2011-11-02T04:09:07Z [Term] id: CMO:0000574 name: blood alanine aminotransferase activity level -def: "The amount of enzymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of blood. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Blood ALT level is used as an enzymatic marker for liver disease or damage." [RGD:737472, Wikipedia:http\://en.wikipedia.org/wiki/Creatine_kinase] +def: "The amount of enzymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of blood. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Blood ALT level is used as an enzymatic marker for liver disease or damage." [RGD:737472, https://en.wikipedia.org/wiki/Creatine_kinase] synonym: "blood alanine transaminase activity level" EXACT [] synonym: "blood ALT activity level" RELATED [] synonym: "blood glutamic-pyruvate transaminase activity level" EXACT [] @@ -4648,7 +4648,7 @@ creation_date: 2011-11-02T04:09:38Z [Term] id: CMO:0000575 name: serum alanine aminotransferase activity level -def: "The amount of ezymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of serum. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Serum ALT level is used as an enzymatic marker for liver disease or damage." [RGD:737472, Wikipedia:http\://en.wikipedia.org/wiki/Creatine_kinase] +def: "The amount of ezymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of serum. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Serum ALT level is used as an enzymatic marker for liver disease or damage." [RGD:737472, https://en.wikipedia.org/wiki/Creatine_kinase] synonym: "serum alanine transaminase activity level" EXACT [] synonym: "serum ALT activity level" RELATED [] synonym: "serum glutamic-pyruvate transaminase activity level" EXACT [] @@ -4699,7 +4699,7 @@ creation_date: 2011-11-02T04:16:29Z [Term] id: CMO:0000580 name: blood aspartate aminotransferase activity level -def: "The amount of enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of blood. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Blood AST level is used as an enzymatic marker for liver disease or damage." [VT:0000203, Wikipedia:http\://en.wikipedia.org/wiki/Aspartate_transaminase] +def: "The amount of enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of blood. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Blood AST level is used as an enzymatic marker for liver disease or damage." [VT:0000203, https://en.wikipedia.org/wiki/Aspartate_transaminase] synonym: "blood aspartate transaminase activity level" EXACT [] synonym: "blood AST activity level" RELATED [] synonym: "blood glutamic-oxaloacetic transaminase activity level" EXACT [] @@ -4712,7 +4712,7 @@ creation_date: 2011-11-02T04:17:35Z [Term] id: CMO:0000581 name: serum aspartate aminotransferase activity level -def: "The amount of enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of serum. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Serum AST level is used as an enzymatic marker for liver disease or damage." [VT:0000203, Wikipedia:http\://en.wikipedia.org/wiki/Aspartate_transaminase] +def: "The amount of enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of serum. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Serum AST level is used as an enzymatic marker for liver disease or damage." [VT:0000203, https://en.wikipedia.org/wiki/Aspartate_transaminase] synonym: "serum aspartate transaminase activity level" EXACT [] synonym: "serum AST activity level" RELATED [] synonym: "serum glutamic-oxaloacetic transaminase activity level" EXACT [] @@ -4830,7 +4830,7 @@ creation_date: 2011-11-03T01:49:22Z [Term] id: CMO:0000595 name: absolute change in plasma renin activity level -def: "The difference in the levels of renin catalytic activity in blood plasma between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in the levels of renin catalytic activity in blood plasma between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0000116 ! plasma renin activity level created_by: mshimoyama @@ -4840,7 +4840,7 @@ creation_date: 2011-11-03T01:54:10Z id: CMO:0000596 name: blood CD4 cell count alt_id: CMO:0000602 -def: "Measurement of the number of lymphocytes expressing the CD4 antigen on their surface in a specified volume of whole blood. CD4 is a membrane glycoprotein found primarily on T lymphocytes, but also can be expressed on B cells, macrophages, and granulocytes. On T cells it is a co-receptor for the T cell receptor (TCR), interacts with MHC class II antigens, and functions to initiate or augment the early phase of T-cell activation." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, RGD:735603, Wikipedia:http\://en.wikipedia.org/wiki/CD4] +def: "Measurement of the number of lymphocytes expressing the CD4 antigen on their surface in a specified volume of whole blood. CD4 is a membrane glycoprotein found primarily on T lymphocytes, but also can be expressed on B cells, macrophages, and granulocytes. On T cells it is a co-receptor for the T cell receptor (TCR), interacts with MHC class II antigens, and functions to initiate or augment the early phase of T-cell activation." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, RGD:735603, https://en.wikipedia.org/wiki/CD4] synonym: "CD4(+) cell count" EXACT [] synonym: "CD4+ cell count" EXACT [] is_a: CMO:0000110 ! blood T lymphocyte count @@ -5173,7 +5173,7 @@ creation_date: 2011-11-03T03:03:02Z [Term] id: CMO:0000635 name: retroperitoneal fat pad weight to body weight ratio -def: "A calculated measurement in which the weight of the retroperitoneal fat pad, the mass of closely packed fat cells surrounded by fibrous tissue located behind the peritoneum, is divided by the total body weight of the organism and the result presented as a ratio, fraction, quotient or percentage thus normalizing it to body weight and, by extension, to the size of the organism." [Dorland:Dorlands_Illustrated_Medical_Dictionary--, ISBN:978-1416049982, Wikipedia:https\://en.wikipedia.org/wiki/Fat_pad] +def: "A calculated measurement in which the weight of the retroperitoneal fat pad, the mass of closely packed fat cells surrounded by fibrous tissue located behind the peritoneum, is divided by the total body weight of the organism and the result presented as a ratio, fraction, quotient or percentage thus normalizing it to body weight and, by extension, to the size of the organism." [Dorland:Dorlands_Illustrated_Medical_Dictionary--, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Fat_pad] synonym: "retroperitoneal fat pad weight as percentage of body weight" RELATED [] is_a: CMO:0000634 ! calculated retroperitoneal fat pad weight created_by: mshimoyama @@ -5270,7 +5270,7 @@ creation_date: 2011-11-03T03:13:20Z [Term] id: CMO:0000646 name: plasma high density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in high-density lipoprotein (HDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in high-density lipoprotein (HDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "plasma HDL-C level" RELATED [] synonym: "plasma HDL level" RELATED [] @@ -5282,7 +5282,7 @@ creation_date: 2011-11-03T03:14:50Z [Term] id: CMO:0000647 name: plasma low density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in low-density lipoprotein (LDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [BioMedCentral:http\://www.biomedcentral.com/1746-6148/9/47, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in low-density lipoprotein (LDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [http://www.biomedcentral.com/1746-6148/9/47, http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "plasma LDL-C level" RELATED [] synonym: "plasma LDL level" RELATED [] @@ -5294,7 +5294,7 @@ creation_date: 2011-11-03T03:15:40Z [Term] id: CMO:0000648 name: blood very low density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "blood VLDL-C level" RELATED [] synonym: "blood VLDL level" RELATED [] @@ -5305,7 +5305,7 @@ creation_date: 2011-11-03T03:16:59Z [Term] id: CMO:0000649 name: plasma very low density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "plasma VLDL-C level" RELATED [] synonym: "plasma VLDL level" RELATED [] @@ -5317,7 +5317,7 @@ creation_date: 2011-11-03T03:17:35Z [Term] id: CMO:0000650 name: serum very low density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "serum VLDL-C level" RELATED [] synonym: "serum VLDL level" RELATED [] @@ -5731,7 +5731,7 @@ creation_date: 2012-03-09T04:05:52Z [Term] id: CMO:0000700 name: blood vessel resistance measurement -def: "Measurement of the amount of resistance in a blood vessel to the flow of blood or other fluid through it." [Wikipedia:http\://en.wikipedia.org] +def: "Measurement of the amount of resistance in a blood vessel to the flow of blood or other fluid through it." [https://en.wikipedia.org] is_a: CMO:0000077 ! blood vessel measurement created_by: JSmith creation_date: 2012-03-09T05:24:30Z @@ -5830,7 +5830,7 @@ creation_date: 2012-03-13T02:08:24Z [Term] id: CMO:0000713 name: dose of methacholine at which pulmonary conductance is half its pretreatment value (ED50) -def: "The administered quantity of methacholine, a quaternary ammonium ion in which the nitrogen is substituted with three methyl groups and a 2-acetoxypropyl group and which acts as a parasympathomimetic bronchoconstrictor, at which the ability of the repiratory tract to allow airflow during breathing (inspration and expiration) is half its value in an untreated subject, or at which the resistance of the respiratory tract to airflow is doubled." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Airway_resistance] +def: "The administered quantity of methacholine, a quaternary ammonium ion in which the nitrogen is substituted with three methyl groups and a 2-acetoxypropyl group and which acts as a parasympathomimetic bronchoconstrictor, at which the ability of the repiratory tract to allow airflow during breathing (inspration and expiration) is half its value in an untreated subject, or at which the resistance of the respiratory tract to airflow is doubled." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Airway_resistance] synonym: "methacholine median effective dose (ED50)" RELATED [] xref: CHEBI:50142 xref: CHEBI:6804 @@ -5858,7 +5858,7 @@ creation_date: 2012-03-13T03:37:25Z [Term] id: CMO:0000716 name: blood vessel contractile force measurement -def: "Any measurement of the energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from contraction of the muscular wall of the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Vasoconstriction] +def: "Any measurement of the energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from contraction of the muscular wall of the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Vasoconstriction] synonym: "blood vessel contractility measurement" RELATED [] is_a: CMO:0000218 ! blood vessel constriction measurement created_by: JSmith @@ -5867,7 +5867,7 @@ creation_date: 2012-03-13T04:15:39Z [Term] id: CMO:0000717 name: blood vessel maximum contractile force -def: "Measurement of the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from contraction of the muscular wall of the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Vasoconstriction] +def: "Measurement of the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from contraction of the muscular wall of the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Vasoconstriction] synonym: "blood vessel maximum contractility measurement" RELATED [] is_a: CMO:0000716 ! blood vessel contractile force measurement created_by: JSmith @@ -5891,7 +5891,7 @@ creation_date: 2012-03-14T04:09:34Z [Term] id: CMO:0000720 name: calculated blood vessel contractile force measurement -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from contraction of the muscular wall of the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Vasoconstriction] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from contraction of the muscular wall of the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Vasoconstriction] is_a: CMO:0000716 ! blood vessel contractile force measurement created_by: JSmith creation_date: 2012-03-14T04:16:11Z @@ -5899,7 +5899,7 @@ creation_date: 2012-03-14T04:16:11Z [Term] id: CMO:0000721 name: concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) -def: "A calculated value for the concentration of phenylephrine (PE), the phenylethanolamine with IUPAC name (R)-3-[-1-hydroxy-2-(methylamino)ethyl]phenol and formula C9H13NO2 that acts as a selective alpha1-adrenergic receptor agonist, decongestant and vasoconstrictor, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of PE is halfway between the baseline value and the highest achievable value of such PE-induced contractile energy." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for the concentration of phenylephrine (PE), the phenylethanolamine with IUPAC name (R)-3-[-1-hydroxy-2-(methylamino)ethyl]phenol and formula C9H13NO2 that acts as a selective alpha1-adrenergic receptor agonist, decongestant and vasoconstrictor, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of PE is halfway between the baseline value and the highest achievable value of such PE-induced contractile energy." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/EC50] synonym: "phenylephrine half maximal effective concentration (EC50)" EXACT [] xref: CHEBI:8093 is_a: CMO:0000739 ! phenylephrine response/sensitivity measurement @@ -5910,7 +5910,7 @@ creation_date: 2012-03-14T04:17:28Z [Term] id: CMO:0000722 name: logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) -def: "A calculated value for logarithm of the concentration of phenylephrine (PE), the phenylethanolamine with IUPAC name (R)-3-[-1-hydroxy-2-(methylamino)ethyl]phenol and formula C9H13NO2 that acts as a selective alpha1-adrenergic receptor agonist, decongestant and vasoconstrictor, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of PE is halfway between the baseline value and the highest achievable value of such PE-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value." [Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for logarithm of the concentration of phenylephrine (PE), the phenylethanolamine with IUPAC name (R)-3-[-1-hydroxy-2-(methylamino)ethyl]phenol and formula C9H13NO2 that acts as a selective alpha1-adrenergic receptor agonist, decongestant and vasoconstrictor, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of PE is halfway between the baseline value and the highest achievable value of such PE-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value." [Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/EC50] synonym: "phenylephrine Log half maximal effective concentration (Log EC50)" EXACT [] xref: CHEBI:8093 is_a: CMO:0000739 ! phenylephrine response/sensitivity measurement @@ -5929,7 +5929,7 @@ creation_date: 2012-03-14T04:21:12Z [Term] id: CMO:0000724 name: concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) -def: "A calculated value for the concentration of acetylcholine (ACh), the ester of acetic acid and choline with chemical formula CH3C=OO(CH2)2-N(+)-(CH3)3 and IUPAC name 2-acetoxy-N,N,N-trimethylethanaminium, which acts as a neurotransmitter, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of ACh is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during ACh-induced relaxation of the vessel wall (i.e. the maximum effect of Ach which is the minimum contractile energy)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for the concentration of acetylcholine (ACh), the ester of acetic acid and choline with chemical formula CH3C=OO(CH2)2-N(+)-(CH3)3 and IUPAC name 2-acetoxy-N,N,N-trimethylethanaminium, which acts as a neurotransmitter, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of ACh is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during ACh-induced relaxation of the vessel wall (i.e. the maximum effect of Ach which is the minimum contractile energy)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/EC50] synonym: "acetylcholine half maximal effective concentration (EC50)" EXACT [] xref: CHEBI:15355 is_a: CMO:0000723 ! calculated blood vessel dilation force reduction measurement @@ -5940,7 +5940,7 @@ creation_date: 2012-03-14T04:23:57Z [Term] id: CMO:0000725 name: logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) -def: "A calculated value for logarithm of the concentration of acetylcholine (ACh), the ester of acetic acid and choline with chemical formula CH3C=OO(CH2)2-N(+)-(CH3)3 and IUPAC name 2-acetoxy-N,N,N-trimethylethanaminium, which acts as a neurotransmitter, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of ACh is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during ACh-induced relaxation of the vessel wall (i.e. the maximum effect of Ach which is the minimum contractile energy). The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value." [Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for logarithm of the concentration of acetylcholine (ACh), the ester of acetic acid and choline with chemical formula CH3C=OO(CH2)2-N(+)-(CH3)3 and IUPAC name 2-acetoxy-N,N,N-trimethylethanaminium, which acts as a neurotransmitter, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of ACh is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during ACh-induced relaxation of the vessel wall (i.e. the maximum effect of Ach which is the minimum contractile energy). The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value." [Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/EC50] synonym: "acetylcholine Log half maximal effective concentration (Log EC50)" EXACT [] xref: CHEBI:15355 is_a: CMO:0000723 ! calculated blood vessel dilation force reduction measurement @@ -5951,7 +5951,7 @@ creation_date: 2012-03-14T04:24:16Z [Term] id: CMO:0000726 name: concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) -def: "A calculated value for the concentration of sodium nitroprusside (SNP), the red-colored inorganic salt with the formula Na2[Fe(CN)5NO]-2H2O used as a potent vasodilator, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of SNP is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during SNP-induced relaxation of the vessel wall (i.e. the maximum effect of SNP which is the minimum contractile energy)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/EC50, Wikipedia:http\\://en.wikipedia.org/wiki/Sodium_nitroprusside] +def: "A calculated value for the concentration of sodium nitroprusside (SNP), the red-colored inorganic salt with the formula Na2[Fe(CN)5NO]-2H2O used as a potent vasodilator, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of SNP is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during SNP-induced relaxation of the vessel wall (i.e. the maximum effect of SNP which is the minimum contractile energy)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/EC50, http://en.wikipedia.org/wiki/Sodium_nitroprusside] synonym: "sodium nitroprusside half maximal effective concentration (EC50)" EXACT [] xref: CHEBI:29321 xref: CHEBI:9179 @@ -5963,7 +5963,7 @@ creation_date: 2012-03-14T04:24:44Z [Term] id: CMO:0000727 name: logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) -def: "A calculated value for logarithm of the concentration of sodium nitroprusside (SNP), the red-coloured inorganic salt with the formula Na2[Fe(CN)5NO]-2H2O used as a potent vasodilator, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of SNP is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during SNP-induced relaxation of the vessel wall (i.e. the maximum effect of SNP which is the minimum contractile energy)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/EC50, Wikipedia:http\\://en.wikipedia.org/wiki/Sodium_nitroprusside] +def: "A calculated value for logarithm of the concentration of sodium nitroprusside (SNP), the red-coloured inorganic salt with the formula Na2[Fe(CN)5NO]-2H2O used as a potent vasodilator, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of SNP is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during SNP-induced relaxation of the vessel wall (i.e. the maximum effect of SNP which is the minimum contractile energy)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/EC50, http://en.wikipedia.org/wiki/Sodium_nitroprusside] synonym: "sodium nitroprusside Log half maximal effective concentration (Log EC50)" EXACT [] xref: CHEBI:29321 xref: CHEBI:9179 @@ -6076,7 +6076,7 @@ creation_date: 2012-03-15T12:12:47Z [Term] id: CMO:0000740 name: sodium nitroprusside response/sensitivity measurement -def: "Measurement of an organism's, organ's, tissue's or cell's capacity to respond, such as by a change in activity, state or condition, to sodium nitroprusside (SNP), the red-colored inorganic salt with the formula Na2[Fe(CN)5NO]-2H2O used as a potent vasodilator." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\\://en.wikipedia.org/wiki/Sodium_nitroprusside] +def: "Measurement of an organism's, organ's, tissue's or cell's capacity to respond, such as by a change in activity, state or condition, to sodium nitroprusside (SNP), the red-colored inorganic salt with the formula Na2[Fe(CN)5NO]-2H2O used as a potent vasodilator." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://en.wikipedia.org/wiki/Sodium_nitroprusside] xref: CHEBI:29321 is_a: CMO:0000719 ! chemical response/sensitivity measurement created_by: JSmith @@ -6333,7 +6333,7 @@ creation_date: 2012-03-28T11:21:06Z [Term] id: CMO:0000771 name: drink intake measurement -def: "The quantification of any parameter related to the process whereby drink, any liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., is taken in for utilization by the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, YourDictionary:http\://www.yourdictionary.com/drink] +def: "The quantification of any parameter related to the process whereby drink, any liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., is taken in for utilization by the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.yourdictionary.com/drink] is_a: CMO:0000426 ! consumption measurement created_by: JSmith creation_date: 2012-03-28T01:37:12Z @@ -6349,7 +6349,7 @@ creation_date: 2012-03-28T01:37:36Z [Term] id: CMO:0000773 name: drink intake volume -def: "Measurement of the size of the three dimensional space occupied by the amount of drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed in a specified period of time." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, YourDictionary:http\://www.yourdictionary.com/drink] +def: "Measurement of the size of the three dimensional space occupied by the amount of drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed in a specified period of time." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, http://www.yourdictionary.com/drink] is_a: CMO:0000771 ! drink intake measurement created_by: JSmith creation_date: 2012-03-28T01:39:39Z @@ -6487,7 +6487,7 @@ creation_date: 2012-06-13T02:55:20Z [Term] id: CMO:0000790 name: milk solids content -def: "The amount of fat, protein, lactose, and minerals in milk." [RGD:JRS, Website:http\://extension.missouri.edu/p/G3110] +def: "The amount of fat, protein, lactose, and minerals in milk." [RGD:JRS, http://extension.missouri.edu/p/G3110] is_a: CMO:0000787 ! milk measurement created_by: JSmith creation_date: 2012-06-13T02:56:57Z @@ -7094,7 +7094,7 @@ creation_date: 2012-06-26T11:34:46Z [Term] id: CMO:0000860 name: organ non-tumorous lesion measurement -def: "Measurement of an organ lesion which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of an organ lesion which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc." [http://www.thefreedictionary.com/] is_a: CMO:0000677 ! organ lesion measurement created_by: JSmith creation_date: 2012-06-26T11:46:40Z @@ -7102,7 +7102,7 @@ creation_date: 2012-06-26T11:46:40Z [Term] id: CMO:0000861 name: heart non-tumorous lesion measurement -def: "Measurement of a heart lesion which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of a heart lesion which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc." [http://www.thefreedictionary.com/] is_a: CMO:0000678 ! heart lesion measurement is_a: CMO:0000860 ! organ non-tumorous lesion measurement created_by: JSmith @@ -7111,7 +7111,7 @@ creation_date: 2012-06-26T12:53:39Z [Term] id: CMO:0000862 name: testis lesion measurement -def: "Measurement of a lesion of the testes, the male reproductive glands that produce spermatozoa and secrete androgens. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of a lesion of the testes, the male reproductive glands that produce spermatozoa and secrete androgens. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined." [http://www.thefreedictionary.com/] is_a: CMO:0000677 ! organ lesion measurement created_by: JSmith creation_date: 2012-06-26T12:59:03Z @@ -7119,7 +7119,7 @@ creation_date: 2012-06-26T12:59:03Z [Term] id: CMO:0000863 name: testis non-tumorous lesion measurement -def: "Measurement of a lesion of the testes, the male reproductive glands that produce spermatozoa and secrete androgens which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of a lesion of the testes, the male reproductive glands that produce spermatozoa and secrete androgens which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc." [http://www.thefreedictionary.com/] is_a: CMO:0000860 ! organ non-tumorous lesion measurement is_a: CMO:0000862 ! testis lesion measurement created_by: JSmith @@ -7128,7 +7128,7 @@ creation_date: 2012-06-26T01:16:01Z [Term] id: CMO:0000864 name: testis tumorous lesion measurement -def: "Measurement of a lesion of the testes, the male reproductive glands that produce spermatozoa and secrete androgens, which is or has the potential to become a tumor, that is, a neoplasm or new growth of tissue in which cell multiplication is more or less uncontrolled and progressive. Tumorous lesions include tumors, preneoplastic lesions, and hyperplastic lesions composed of histologically normal cells." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of a lesion of the testes, the male reproductive glands that produce spermatozoa and secrete androgens, which is or has the potential to become a tumor, that is, a neoplasm or new growth of tissue in which cell multiplication is more or less uncontrolled and progressive. Tumorous lesions include tumors, preneoplastic lesions, and hyperplastic lesions composed of histologically normal cells." [http://www.thefreedictionary.com/] is_a: CMO:0000859 ! organ tumorous lesion measurement is_a: CMO:0000862 ! testis lesion measurement created_by: JSmith @@ -7206,7 +7206,7 @@ creation_date: 2012-07-02T11:52:20Z [Term] id: CMO:0000873 name: absolute change in adipocyte glucose uptake -def: "The difference in the amount of glucose transported into a fat cell between two conditions, for example between the basal or baseline state and a stimulated state, such as occurs with administration of insulin." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "The difference in the amount of glucose transported into a fat cell between two conditions, for example between the basal or baseline state and a stimulated state, such as occurs with administration of insulin." [http://www.thefreedictionary.com/] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "incremental glucose uptake" RELATED [] is_a: CMO:0000872 ! calculated adipocyte glucose uptake measurement @@ -7225,7 +7225,7 @@ creation_date: 2012-07-02T11:55:35Z [Term] id: CMO:0000875 name: adipocyte free fatty acid secretion measurement -def: "Measurement of the amount of free fatty acids, i.e. those not bound to other molecules or moieties, secreted from a fat cell. Free fatty acid secretion can be used as a measure of lipolysis in adipocytes." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of the amount of free fatty acids, i.e. those not bound to other molecules or moieties, secreted from a fat cell. Free fatty acid secretion can be used as a measure of lipolysis in adipocytes." [http://www.thefreedictionary.com/] synonym: "adipocyte free fatty acid release measurement" EXACT [] synonym: "adipocyte NEFA release measurement" RELATED [] synonym: "adipocyte NEFA secretion measurement" RELATED [] @@ -7276,7 +7276,7 @@ creation_date: 2012-07-03T09:12:05Z [Term] id: CMO:0000879 name: absolute change in adipocyte free fatty acid secretion -def: "The difference in the amount of free or non-esterified fatty acid released/secreted from a fat cell between two conditions, for example between the basal or baseline state and a stimulated state, such as occurs with administration of a hormone which stimulates lipolysis." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "The difference in the amount of free or non-esterified fatty acid released/secreted from a fat cell between two conditions, for example between the basal or baseline state and a stimulated state, such as occurs with administration of a hormone which stimulates lipolysis." [http://www.thefreedictionary.com/] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in adipocyte free fatty acid release" EXACT [] synonym: "absolute change in adipocyte NEFA release" RELATED [] @@ -7543,7 +7543,7 @@ creation_date: 2012-07-11T10:34:14Z [Term] id: CMO:0000907 name: renal blood flow rate -def: "Renal blood flow (RBF) is the volume of blood delivered to or exiting from the kidneys per unit time." [Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "Renal blood flow (RBF) is the volume of blood delivered to or exiting from the kidneys per unit time." [https://en.wikipedia.org/wiki/Renal_blood_flow] is_a: CMO:0000196 ! blood flow rate is_a: CMO:0000906 ! kidney measurement created_by: JSmith @@ -7552,7 +7552,7 @@ creation_date: 2012-07-11T10:38:08Z [Term] id: CMO:0000908 name: renal arterial blood flow rate -def: "Arterial renal blood flow (RBFa) is the volume of blood delivered to the kidneys per unit time via the renal arteries." [Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "Arterial renal blood flow (RBFa) is the volume of blood delivered to the kidneys per unit time via the renal arteries." [https://en.wikipedia.org/wiki/Renal_blood_flow] is_a: CMO:0000198 ! arterial blood flow rate is_a: CMO:0000907 ! renal blood flow rate created_by: JSmith @@ -7561,7 +7561,7 @@ creation_date: 2012-07-11T10:44:48Z [Term] id: CMO:0000909 name: renal venous blood flow rate -def: "Venous renal blood flow (RBFv) is the volume of blood exiting from the kidneys per unit time via the renal veins." [Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "Venous renal blood flow (RBFv) is the volume of blood exiting from the kidneys per unit time via the renal veins." [https://en.wikipedia.org/wiki/Renal_blood_flow] is_a: CMO:0000199 ! venous blood flow rate is_a: CMO:0000907 ! renal blood flow rate created_by: JSmith @@ -7591,7 +7591,7 @@ creation_date: 2012-07-11T11:08:16Z [Term] id: CMO:0000912 name: brain non-tumorous lesion measurement -def: "Measurement of a brain lesion which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of a brain lesion which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc." [http://www.thefreedictionary.com/] is_a: CMO:0000860 ! organ non-tumorous lesion measurement is_a: CMO:0000910 ! brain lesion measurement created_by: JSmith @@ -7600,7 +7600,7 @@ creation_date: 2012-07-11T11:20:13Z [Term] id: CMO:0000913 name: brain tumorous lesion measurement -def: "Measurement of an organ lesion which is or has the potential to become a tumor, that is, a neoplasm or new growth of tissue in which cell multiplication is more or less uncontrolled and progressive. Tumorous lesions include tumors, preneoplastic lesions, and hyperplastic lesions composed of histologically normal cells." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of an organ lesion which is or has the potential to become a tumor, that is, a neoplasm or new growth of tissue in which cell multiplication is more or less uncontrolled and progressive. Tumorous lesions include tumors, preneoplastic lesions, and hyperplastic lesions composed of histologically normal cells." [http://www.thefreedictionary.com/] is_a: CMO:0000859 ! organ tumorous lesion measurement is_a: CMO:0000910 ! brain lesion measurement created_by: JSmith @@ -7683,7 +7683,7 @@ creation_date: 2012-07-12T01:29:59Z [Term] id: CMO:0000923 name: platelet function measurement -def: "Any measurement which is used to assess the ability of platelets to become activated, aggregate and promote clotting." [Website:http\://labtestsonline.org/] +def: "Any measurement which is used to assess the ability of platelets to become activated, aggregate and promote clotting." [http://labtestsonline.org/] is_a: CMO:0003101 ! platelet physiological measurement created_by: JSmith creation_date: 2012-07-12T01:37:06Z @@ -7951,7 +7951,7 @@ creation_date: 2012-07-18T04:24:26Z [Term] id: CMO:0000952 name: heart right ventricle morphological measurement -def: "Any measurement of the physical form or structure of the right ventricle of the heart. The right ventricle is the lower chamber of the right side of the heart (from the perspective of the organism rather than the observer), which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location] +def: "Any measurement of the physical form or structure of the right ventricle of the heart. The right ventricle is the lower chamber of the right side of the heart (from the perspective of the organism rather than the observer), which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Anatomical_terms_of_location] is_a: CMO:0000339 ! heart ventricle morphological measurement created_by: JSmith creation_date: 2012-07-18T04:30:51Z @@ -8222,7 +8222,7 @@ creation_date: 2012-07-26T03:24:53Z [Term] id: CMO:0000982 name: heart left ventricular end-diastolic diameter -def: "The diameter across the left ventricle of the heart at the end of diastole, that is, when the heart muscle is maximally relaxed, and usually corresponds to its largest diameter." [Wikipedia:http\://en.wikipedia.org/wiki/Ventricle_%28heart%29] +def: "The diameter across the left ventricle of the heart at the end of diastole, that is, when the heart muscle is maximally relaxed, and usually corresponds to its largest diameter." [https://en.wikipedia.org/wiki/Ventricle_%28heart%29] synonym: "left ventricular end-diastolic dimension" RELATED [] synonym: "LVDD" RELATED [] synonym: "LVEDD" RELATED [] @@ -8233,7 +8233,7 @@ creation_date: 2012-07-27T03:14:05Z [Term] id: CMO:0000983 name: heart left ventricle end-systolic diameter -def: "The diameter across the left ventricle of the heart at the end of systole, that is, when the heart muscle is maximally contracted, and usually corresponds to its smallest diameter." [Wikipedia:http\://en.wikipedia.org/wiki/Ventricle_%28heart%29] +def: "The diameter across the left ventricle of the heart at the end of systole, that is, when the heart muscle is maximally contracted, and usually corresponds to its smallest diameter." [https://en.wikipedia.org/wiki/Ventricle_%28heart%29] synonym: "left ventricular end-systolic dimension" RELATED [] synonym: "LVESD" RELATED [] synonym: "LVSD" RELATED [] @@ -8252,7 +8252,7 @@ creation_date: 2012-07-27T03:42:40Z [Term] id: CMO:0000985 name: heart left ventricle fractional shortening -def: "A calculated measurement corresponding to the ratio or percent reduction in left ventricular diameter between end-diastole and end-systole. Can be calculated as the left ventricle end-diastolic diameter (LVDd) minus the left ventricle end-systolic diameter (LVSd) divided by the left ventricle end-diastolic diameter (LVDd) with the quotient multiplied by 100, i.e. FS = [(LVDd-LVSd)/LVDd] x 100." [Wikipedia:http\://en.wikipedia.org/wiki/Ventricle_%28heart%29] +def: "A calculated measurement corresponding to the ratio or percent reduction in left ventricular diameter between end-diastole and end-systole. Can be calculated as the left ventricle end-diastolic diameter (LVDd) minus the left ventricle end-systolic diameter (LVSd) divided by the left ventricle end-diastolic diameter (LVDd) with the quotient multiplied by 100, i.e. FS = [(LVDd-LVSd)/LVDd] x 100." [https://en.wikipedia.org/wiki/Ventricle_%28heart%29] is_a: CMO:0000984 ! calculated heart left ventricle morphological measurement created_by: JSmith creation_date: 2012-07-27T03:51:33Z @@ -8285,7 +8285,7 @@ creation_date: 2012-07-27T05:59:34Z [Term] id: CMO:0000988 name: heart left ventricle relative wall thickness -def: "A calculated measurement of left ventricular geometry and is calculated by dividing the end-diastolic diameter into 2x the posterior wall thickness, 2x the septal wall thickness or the sum of the posterior and septal wall thicknesses. It represents a measure of the wall thickness normalized to the size of the ventricle lumen." [Website:http\://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S883] +def: "A calculated measurement of left ventricular geometry and is calculated by dividing the end-diastolic diameter into 2x the posterior wall thickness, 2x the septal wall thickness or the sum of the posterior and septal wall thicknesses. It represents a measure of the wall thickness normalized to the size of the ventricle lumen." [http://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S883] is_a: CMO:0000984 ! calculated heart left ventricle morphological measurement is_a: CMO:0000993 ! heart ventricle relative wall thickness created_by: JSmith @@ -8294,7 +8294,7 @@ creation_date: 2012-07-27T06:00:34Z [Term] id: CMO:0000989 name: heart left ventricle end-diastolic relative wall thickness -def: "A calculated measurement of left ventricular geometry and is calculated by dividing the end-diastolic diameter into 2x the posterior wall thickness at end-diastole, 2x the septal wall thickness at end-diastole or the sum of the posterior and septal wall thicknesses at end-diastole. It represents a measure of the wall thickness normalized to the size of the ventricle lumen." [Website:http\://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S883] +def: "A calculated measurement of left ventricular geometry and is calculated by dividing the end-diastolic diameter into 2x the posterior wall thickness at end-diastole, 2x the septal wall thickness at end-diastole or the sum of the posterior and septal wall thicknesses at end-diastole. It represents a measure of the wall thickness normalized to the size of the ventricle lumen." [http://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S883] is_a: CMO:0000988 ! heart left ventricle relative wall thickness created_by: JSmith creation_date: 2012-07-27T06:15:29Z @@ -8419,7 +8419,7 @@ creation_date: 2012-08-02T03:51:38Z [Term] id: CMO:0001004 name: blood steroid hormone level -def: "Measurement of the amount in blood of an organic compound the basis of which is a characteristic arrangement of four fused cycloalkane rings, i.e. three cyclohexane rings and one cyclopentane ring, that is produced in one part or organ of the body and initiates or regulates the activity of an organ or a group of cells in another part of the body." [Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Steroid] +def: "Measurement of the amount in blood of an organic compound the basis of which is a characteristic arrangement of four fused cycloalkane rings, i.e. three cyclohexane rings and one cyclopentane ring, that is produced in one part or organ of the body and initiates or regulates the activity of an organ or a group of cells in another part of the body." [Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Steroid] is_a: CMO:0000039 ! blood steroid level is_a: CMO:0001003 ! blood hormone level created_by: JSmith @@ -8601,7 +8601,7 @@ creation_date: 2012-08-21T11:51:52Z [Term] id: CMO:0001024 name: percentage of deaths in a study population during a period of time -def: "The total number of deaths occurring during a specified period of time within a study population divided by the total number of individuals in the study population, expressed as a percentage." [Wikipedia:http\://en.wikipedia.org/wiki/Mortality_rate] +def: "The total number of deaths occurring during a specified period of time within a study population divided by the total number of individuals in the study population, expressed as a percentage." [https://en.wikipedia.org/wiki/Mortality_rate] synonym: "death incidence measurement as percent" RELATED [] synonym: "death rate" RELATED [] synonym: "mortality rate" RELATED [] @@ -8733,7 +8733,7 @@ creation_date: 2012-08-23T04:24:11Z [Term] id: CMO:0001038 name: stretched-attend posture measurement -def: "Any measurement of the movement of an experimental subject or organism during which the hind legs remain stationary while the body is stretched forward with head raised." [Website:https\://workspace.stanford.edu/sites/mousebehavior/Wiki%20Pages/Investigate%20-%20stretched%20attend.aspx] +def: "Any measurement of the movement of an experimental subject or organism during which the hind legs remain stationary while the body is stretched forward with head raised." [https://workspace.stanford.edu/sites/mousebehavior/Wiki%20Pages/Investigate%20-%20stretched%20attend.aspx] synonym: "Not4Curation" RELATED [] synonym: "SAP measurement" RELATED [] synonym: "stretch-attend posture measurement" EXACT [] @@ -8744,7 +8744,7 @@ creation_date: 2012-08-23T04:39:54Z [Term] id: CMO:0001039 name: number of stretched-attend posture movements -def: "Measurement of the number of times an experimental subject or organism displays a stretched-attend posture movement during an experimental time period. The stretched-attend posture is one during which the hind legs remain stationary while the body is stretched forward with head raised." [Website:https\://workspace.stanford.edu/sites/mousebehavior/Wiki%20Pages/Investigate%20-%20stretched%20attend.aspx] +def: "Measurement of the number of times an experimental subject or organism displays a stretched-attend posture movement during an experimental time period. The stretched-attend posture is one during which the hind legs remain stationary while the body is stretched forward with head raised." [https://workspace.stanford.edu/sites/mousebehavior/Wiki%20Pages/Investigate%20-%20stretched%20attend.aspx] synonym: "number of SAP movements" RELATED [] synonym: "number of stretch-attend posture movements" EXACT [] is_a: CMO:0001038 ! stretched-attend posture measurement @@ -8814,7 +8814,7 @@ creation_date: 2012-08-27T10:28:46Z [Term] id: CMO:0001046 name: experimental autoimmune encephalomyelitis incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display experimental autoimmune encephalomyelitis (EAE) at a point in time or develop EAE within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells." [Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "Any measurement in which the number of individuals in a study population that display experimental autoimmune encephalomyelitis (EAE) at a point in time or develop EAE within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells." [https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "EAE incidence/prevalence measurement" EXACT [] synonym: "experimental allergic encephalomyelitis incidence/prevalence measurement" EXACT [] synonym: "Not4Curation" RELATED [] @@ -8825,7 +8825,7 @@ creation_date: 2012-08-27T11:03:49Z [Term] id: CMO:0001047 name: percentage of study population developing experimental autoimmune encephalomyelitis during a period of time -def: "The number of new cases of experimental autoimmune encephalomyelitis (EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells." [Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of new cases of experimental autoimmune encephalomyelitis (EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells." [https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "EAE incidence" RELATED [] synonym: "experimental allergic encephalomyelitis incidence" RELATED [] synonym: "experimental autoimmune encephalomyelitis incidence" RELATED [] @@ -8837,7 +8837,7 @@ creation_date: 2012-08-27T11:11:03Z [Term] id: CMO:0001048 name: percentage of study population displaying experimental autoimmune encephalomyelitis at a point in time -def: "The number of individuals in a study population which display experimental autoimmune encephalomyelitis (EAE) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells." [Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of individuals in a study population which display experimental autoimmune encephalomyelitis (EAE) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells." [https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "EAE prevalence" RELATED [] synonym: "experimental allergic encephalomyelitis prevalence" RELATED [] synonym: "experimental autoimmune encephalomyelitis prevalence" RELATED [] @@ -9172,7 +9172,7 @@ creation_date: 2012-09-04T04:40:53Z [Term] id: CMO:0001084 name: mammary gland terminal end bud count -def: "Measurement of the number of mammary gland terminal end buds in a specified sample. Terminal end buds are the highly proliferative structures found at the tips of mammary ducts as they elongate into the mammary fat pad during mammary gland development." [Wikipedia:http\://en.wikipedia.org/wiki/Mammary_gland_development] +def: "Measurement of the number of mammary gland terminal end buds in a specified sample. Terminal end buds are the highly proliferative structures found at the tips of mammary ducts as they elongate into the mammary fat pad during mammary gland development." [https://en.wikipedia.org/wiki/Mammary_gland_development] is_a: CMO:0001083 ! mammary gland morphological measurement created_by: jsmith creation_date: 2012-09-04T04:45:52Z @@ -9190,7 +9190,7 @@ creation_date: 2012-09-04T06:12:08Z [Term] id: CMO:0001086 name: blood natural killer T cell count -def: "The number of natural killer T (NKT) cells in a specified volume of blood. NKT cells are a specialized population of T cells that express both a semi-invariant T cell receptor (TCR alpha beta) and surface antigens typically associated with natural killer cells." [Website:http\://www.rndsystems.com/molecule_group.aspx?g=2851&r=4&g2=695] +def: "The number of natural killer T (NKT) cells in a specified volume of blood. NKT cells are a specialized population of T cells that express both a semi-invariant T cell receptor (TCR alpha beta) and surface antigens typically associated with natural killer cells." [http://www.rndsystems.com/molecule_group.aspx?g=2851&r=4&g2=695] comment: This term is not to be used for natural killer (NK) cells. synonym: "NKT cell count" EXACT [] is_a: CMO:0000110 ! blood T lymphocyte count @@ -9301,7 +9301,7 @@ creation_date: 2012-09-12T05:42:06Z [Term] id: CMO:0001098 name: TUNEL-positive cell number to total cell number ratio -def: "A calculated measurement in which the number of cells in a specified sample that stain positively in the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay (i.e. in which the DNA is fragmented and therefore is labeled by the terminal transferase, a marker of apoptosis) is divided by the total number of cells in the sample, and presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/TUNEL_assay] +def: "A calculated measurement in which the number of cells in a specified sample that stain positively in the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay (i.e. in which the DNA is fragmented and therefore is labeled by the terminal transferase, a marker of apoptosis) is divided by the total number of cells in the sample, and presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/TUNEL_assay] synonym: "number of apoptotic cells as percentage of total number of cells" RELATED [] synonym: "number of TUNEL-positivecells as percentage of total number of cells" RELATED [] is_a: CMO:0001097 ! calculated apoptotic cell measurement @@ -9439,7 +9439,7 @@ creation_date: 2012-09-13T11:57:04Z [Term] id: CMO:0001113 name: diabetes mellitus incidence/prevalence measurement -def: "Any measurement which expresses either the total number of cases of diabetes mellitus in a population at a given point in time or the rate of occurrence of new cases of diabetes mellitus, that is, the proportion of the population which develop the condition within a period of time." [Wikipedia:http\://en.wikipedia.org/wiki/Incidence_%28epidemiology%29#Incidence_vs._prevalence] +def: "Any measurement which expresses either the total number of cases of diabetes mellitus in a population at a given point in time or the rate of occurrence of new cases of diabetes mellitus, that is, the proportion of the population which develop the condition within a period of time." [https://en.wikipedia.org/wiki/Incidence_%28epidemiology%29#Incidence_vs._prevalence] synonym: "Not4Curation" RELATED [] is_a: CMO:0000926 ! disease incidence/prevalence measurement created_by: JSmith @@ -9485,7 +9485,7 @@ creation_date: 2012-09-13T03:56:46Z [Term] id: CMO:0001118 name: liver ornithine decarboxylase activity -def: "Measurement in a specified sample of liver of the amount of ezymatic activity of ornithine decarboxylase, that is, the ability of the protein to catalyze the decarboxylation of ornithine (a product of the urea cycle) to form putrescine, the rate-limiting and first committed step in polyamine synthesis. The liver is the large, dark-red organ located in the cranial portion of the abdomen of vertebrates, just behind or below the diaphragm, the functions of which include storage and filtration of blood; secretion of bile; detoxification of noxious substances; conversion of sugars into glycogen; synthesis and breakdown of fats and temporary storage of fatty acids; and synthesis of serum proteins." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Ornithine_decarboxylase] +def: "Measurement in a specified sample of liver of the amount of ezymatic activity of ornithine decarboxylase, that is, the ability of the protein to catalyze the decarboxylation of ornithine (a product of the urea cycle) to form putrescine, the rate-limiting and first committed step in polyamine synthesis. The liver is the large, dark-red organ located in the cranial portion of the abdomen of vertebrates, just behind or below the diaphragm, the functions of which include storage and filtration of blood; secretion of bile; detoxification of noxious substances; conversion of sugars into glycogen; synthesis and breakdown of fats and temporary storage of fatty acids; and synthesis of serum proteins." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Ornithine_decarboxylase] synonym: "hepatic ornithine decarboxylase activity" EXACT [] synonym: "liver ODC activity" RELATED [] xref: EC:4.1.1.17 @@ -9507,7 +9507,7 @@ creation_date: 2012-09-13T05:27:15Z [Term] id: CMO:0001120 name: blood R73 cell to total mononuclear cell ratio -def: "A calculated measurement in which the number of lymphocytes in a sample of blood which express a surface antigen recognised by R73 is divided by the total number of mononuclear cells in that sample, and presented as a ratio, fraction, quotient or percentage. A mononuclear cell is a leukocyte with a one-lobed nucleus and without cytoplasmic granules." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Mononuclear_cell] +def: "A calculated measurement in which the number of lymphocytes in a sample of blood which express a surface antigen recognised by R73 is divided by the total number of mononuclear cells in that sample, and presented as a ratio, fraction, quotient or percentage. A mononuclear cell is a leukocyte with a one-lobed nucleus and without cytoplasmic granules." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Mononuclear_cell] is_a: CMO:0001119 ! blood R73 cell count created_by: JSmith creation_date: 2012-09-13T05:30:11Z @@ -9568,7 +9568,7 @@ creation_date: 2012-10-03T05:31:53Z [Term] id: CMO:0001127 name: anterior cerebral artery inner diameter -def: "The length of a line which crosses a transverse view of an anterior cerebral artery, passing through its center and ending on either side at the inner surface of the blood vessel wall. The anterior cerebral artery (ACA) is one of a pair of arteries that supply oxygenated blood to the most medial portions of the frontal lobes and superior medial parietal lobes of the brain." [RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Anterior_cerebral_artery] +def: "The length of a line which crosses a transverse view of an anterior cerebral artery, passing through its center and ending on either side at the inner surface of the blood vessel wall. The anterior cerebral artery (ACA) is one of a pair of arteries that supply oxygenated blood to the most medial portions of the frontal lobes and superior medial parietal lobes of the brain." [RGD:JRS, https://en.wikipedia.org/wiki/Anterior_cerebral_artery] synonym: "ACA inner diameter" RELATED [] synonym: "anterior cerebral artery lumen diameter" RELATED [] is_a: CMO:0001126 ! cerebral artery inner diameter @@ -9578,7 +9578,7 @@ creation_date: 2012-10-03T05:39:47Z [Term] id: CMO:0001128 name: middle cerebral artery inner diameter -def: "The length of a line which crosses a transverse view of a middle cerebral artery, passing through its center and ending on either side at the inner surface of the blood vessel wall. The middle cerebral arteries are the largest of the cerebral arteries and supply blood to the lateral cerebral cortex, anterior temporal lobes and insular cortices of the brain." [RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Middle_cerebral_artery] +def: "The length of a line which crosses a transverse view of a middle cerebral artery, passing through its center and ending on either side at the inner surface of the blood vessel wall. The middle cerebral arteries are the largest of the cerebral arteries and supply blood to the lateral cerebral cortex, anterior temporal lobes and insular cortices of the brain." [RGD:JRS, https://en.wikipedia.org/wiki/Middle_cerebral_artery] synonym: "MCA inner diameter" RELATED [] synonym: "middle cerebral artery lumen diameter" RELATED [] is_a: CMO:0001126 ! cerebral artery inner diameter @@ -9588,7 +9588,7 @@ creation_date: 2012-10-03T05:48:00Z [Term] id: CMO:0001129 name: posterior cerebral artery inner diameter -def: "The length of a line which crosses a transverse view of a posterior cerebral artery, passing through its center and ending on either side at the inner surface of the blood vessel wall. The posterior cerebral artery (PCA) is one of a pair of blood vessels that supply blood to the posterior aspect, i.e. the occipital lobe, of the brain." [RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Posterior_cerebral_artery] +def: "The length of a line which crosses a transverse view of a posterior cerebral artery, passing through its center and ending on either side at the inner surface of the blood vessel wall. The posterior cerebral artery (PCA) is one of a pair of blood vessels that supply blood to the posterior aspect, i.e. the occipital lobe, of the brain." [RGD:JRS, https://en.wikipedia.org/wiki/Posterior_cerebral_artery] synonym: "PCA inner diameter" RELATED [] synonym: "posterior cerebral artery lumen diameter" RELATED [] is_a: CMO:0001126 ! cerebral artery inner diameter @@ -9659,7 +9659,7 @@ creation_date: 2012-10-08T03:45:56Z [Term] id: CMO:0001136 name: percentage of study population developing type 1 diabetes mellitus during a period of time -def: "The number of new cases of type 1 diabetes mellitus (T1DM) appearing in a study population during a specified period compared to the total number of individuals in the study population, expressed as a percentage. T1DM is a form of diabetes mellitus which results from the autoimmune destruction of beta cells of the pancreatic islets of Langerhans." [Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_1] +def: "The number of new cases of type 1 diabetes mellitus (T1DM) appearing in a study population during a specified period compared to the total number of individuals in the study population, expressed as a percentage. T1DM is a form of diabetes mellitus which results from the autoimmune destruction of beta cells of the pancreatic islets of Langerhans." [https://en.wikipedia.org/wiki/Diabetes_mellitus_type_1] synonym: "diabetes mellitus type I incidence" RELATED [] synonym: "IDDM incidence" RELATED [] synonym: "insulin-dependent diabetes incidence" RELATED [] @@ -9674,7 +9674,7 @@ creation_date: 2012-10-09T10:55:37Z [Term] id: CMO:0001137 name: percentage of study population developing type 2 diabetes mellitus during a period of time -def: "The number of new cases of type 2 diabetes mellitus appearing in a study population during a specified period compared to the total number of individuals in the study population, expressed as a percentage. T2DM is a form of diabetes often, although not universally, associated with obesity, insulin resistance, hyperlipidemia(s) and cardiovascular symptoms such as hypertension." [Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] +def: "The number of new cases of type 2 diabetes mellitus appearing in a study population during a specified period compared to the total number of individuals in the study population, expressed as a percentage. T2DM is a form of diabetes often, although not universally, associated with obesity, insulin resistance, hyperlipidemia(s) and cardiovascular symptoms such as hypertension." [https://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] synonym: "adult-onset diabetes mellitus incidence" RELATED [] synonym: "diabetes mellitus type II incidence" RELATED [] synonym: "NIDDM incidence" RELATED [] @@ -9689,7 +9689,7 @@ creation_date: 2012-10-09T10:59:15Z [Term] id: CMO:0001138 name: percentage of study population displaying type 1 diabetes mellitus at a point in time -def: "The number of individuals in a study population which display type 1 diabetes mellitus (T1DM) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. T1DM is a form of diabetes mellitus which results from the autoimmune destruction of beta cells of the pancreatic islets of Langerhans." [Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_1] +def: "The number of individuals in a study population which display type 1 diabetes mellitus (T1DM) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. T1DM is a form of diabetes mellitus which results from the autoimmune destruction of beta cells of the pancreatic islets of Langerhans." [https://en.wikipedia.org/wiki/Diabetes_mellitus_type_1] synonym: "diabetes mellitus type I prevalence" RELATED [] synonym: "IDDM prevalence" RELATED [] synonym: "insulin-dependent diabetes prevalence" RELATED [] @@ -9704,7 +9704,7 @@ creation_date: 2012-10-09T11:03:00Z [Term] id: CMO:0001139 name: percentage of study population displaying type 2 diabetes mellitus at a point in time -def: "The number of individuals in a study population which display type 2 diabetes mellitus (T2DM) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. T2DM is a form of diabetes often, although not universally, associated with obesity, insulin resistance, hyperlipidemia(s) and cardiovascular symptoms such as hypertension." [Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] +def: "The number of individuals in a study population which display type 2 diabetes mellitus (T2DM) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. T2DM is a form of diabetes often, although not universally, associated with obesity, insulin resistance, hyperlipidemia(s) and cardiovascular symptoms such as hypertension." [https://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] synonym: "adult-onset diabetes mellitus prevalence" RELATED [] synonym: "diabetes mellitus type II prevalence" RELATED [] synonym: "NIDDM prevalence" RELATED [] @@ -9719,7 +9719,7 @@ creation_date: 2012-10-09T11:04:39Z [Term] id: CMO:0001140 name: age at onset/diagnosis of type 1 diabetes mellitus -def: "A measurement of the chronological age, that is, the length of time since birth, of the individual when the symptoms of type 1 diabetes mellitus (T1DM) first appeared, or when an official diagnosis of T1DM was first determined. T1DM is a form of diabetes mellitus which results from the autoimmune destruction of beta cells of the pancreatic islets of Langerhans." [McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_1] +def: "A measurement of the chronological age, that is, the length of time since birth, of the individual when the symptoms of type 1 diabetes mellitus (T1DM) first appeared, or when an official diagnosis of T1DM was first determined. T1DM is a form of diabetes mellitus which results from the autoimmune destruction of beta cells of the pancreatic islets of Langerhans." [McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, https://en.wikipedia.org/wiki/Diabetes_mellitus_type_1] synonym: "age at onset/diagnosis of diabetes mellitus type I" EXACT [] synonym: "age at onset/diagnosis of IDDM" RELATED [] synonym: "age at onset/diagnosis of insulin-dependent diabetes" RELATED [] @@ -9733,7 +9733,7 @@ creation_date: 2012-10-09T11:42:58Z [Term] id: CMO:0001141 name: age at onset/diagnosis of type 2 diabetes mellitus -def: "A measurement of the chronological age, that is, the length of time since birth, of the individual when the symptoms of type 2 diabetes mellitus (T2DM) first appeared, or when an official diagnosis of T2DM was first determined. T2DM is a form of diabetes often, although not universally, associated with obesity, insulin resistance, hyperlipidemia(s) and cardiovascular symptoms such as hypertension." [McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] +def: "A measurement of the chronological age, that is, the length of time since birth, of the individual when the symptoms of type 2 diabetes mellitus (T2DM) first appeared, or when an official diagnosis of T2DM was first determined. T2DM is a form of diabetes often, although not universally, associated with obesity, insulin resistance, hyperlipidemia(s) and cardiovascular symptoms such as hypertension." [McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, https://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] synonym: "age at onset/diagnosis of adult-onset diabetes mellitus" RELATED [] synonym: "age at onset/diagnosis of diabetes mellitus type II" EXACT [] synonym: "age at onset/diagnosis of NIDDM" RELATED [] @@ -9776,7 +9776,7 @@ creation_date: 2012-10-09T01:09:30Z [Term] id: CMO:0001145 name: calculated intramuscular fat morphological measurement -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the physical form or structure of the small deposits of fat located within and throughout skeletal muscle." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Intramuscular_fat] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the physical form or structure of the small deposits of fat located within and throughout skeletal muscle." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Intramuscular_fat] is_a: CMO:0000208 ! intramuscular fat morphological measurement is_a: CMO:0001146 ! calculated skeletal muscle morphological measurement created_by: JSmith @@ -9951,7 +9951,7 @@ creation_date: 2012-10-15T11:08:36Z [Term] id: CMO:0001164 name: calculated intramuscular fat weight -def: "A measurement of the amount, by weight, of the small deposits of fat located within a specified amount of skeletal muscle, which has been normalized, adjusted or derived by a mathematical process or computation." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Intramuscular_fat] +def: "A measurement of the amount, by weight, of the small deposits of fat located within a specified amount of skeletal muscle, which has been normalized, adjusted or derived by a mathematical process or computation." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Intramuscular_fat] is_a: CMO:0000193 ! intramuscular fat weight is_a: CMO:0001145 ! calculated intramuscular fat morphological measurement created_by: JSmith @@ -9977,7 +9977,7 @@ creation_date: 2012-10-15T11:48:00Z [Term] id: CMO:0001167 name: calculated renal blood flow rate -def: "A measurement of the volume of blood delivered to or exiting from the kidneys per unit time, which has been normalized, adjusted or derived by a mathematical process or computation." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "A measurement of the volume of blood delivered to or exiting from the kidneys per unit time, which has been normalized, adjusted or derived by a mathematical process or computation." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Renal_blood_flow] is_a: CMO:0000907 ! renal blood flow rate created_by: JSmith creation_date: 2012-10-15T11:55:42Z @@ -9985,7 +9985,7 @@ creation_date: 2012-10-15T11:55:42Z [Term] id: CMO:0001168 name: absolute change in renal blood flow rate -def: "The difference in the volume of blood delivered to or exiting from the kidneys per unit time between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F, Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "The difference in the volume of blood delivered to or exiting from the kidneys per unit time between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [http://www.psychwiki.com/wiki/What_is_absolute_change%3F, https://en.wikipedia.org/wiki/Renal_blood_flow] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0001167 ! calculated renal blood flow rate created_by: JSmith @@ -10083,7 +10083,7 @@ creation_date: 2012-10-22T03:13:42Z [Term] id: CMO:0001179 name: renal medulla measurement -def: "Any measurement, morphological or physiological, of the renal medulla, the innermost part of the kidney which contains the structures of the nephrons responsible for maintaining the salt and water balance of the blood." [Wikipedia:http\://en.wikipedia.org/wiki/Renal_medulla] +def: "Any measurement, morphological or physiological, of the renal medulla, the innermost part of the kidney which contains the structures of the nephrons responsible for maintaining the salt and water balance of the blood." [https://en.wikipedia.org/wiki/Renal_medulla] synonym: "kidney medulla measurement" EXACT [] is_a: CMO:0000906 ! kidney measurement created_by: JSmith @@ -10092,7 +10092,7 @@ creation_date: 2012-10-22T03:20:09Z [Term] id: CMO:0001180 name: renal medulla protein measurement -def: "Any measurement involving the amount, composition or type of protein, the complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in kidney medulla, the innermost part of the kidney which contains the structures of the nephrons responsible for maintaining the salt and water balance of the blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Renal_medulla] +def: "Any measurement involving the amount, composition or type of protein, the complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in kidney medulla, the innermost part of the kidney which contains the structures of the nephrons responsible for maintaining the salt and water balance of the blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Renal_medulla] synonym: "kidney medulla protein measurement" EXACT [] is_a: CMO:0001179 ! renal medulla measurement created_by: JSmith @@ -10129,7 +10129,7 @@ creation_date: 2012-10-22T03:41:53Z [Term] id: CMO:0001184 name: calculated renal medulla protein composition measurement -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation involving the amount, composition or type of protein in the renal medulla, the innermost part of the kidney which contains the structures of the nephrons responsible for maintaining the salt and water balance of the blood." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Renal_medulla] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation involving the amount, composition or type of protein in the renal medulla, the innermost part of the kidney which contains the structures of the nephrons responsible for maintaining the salt and water balance of the blood." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Renal_medulla] synonym: "calculated kidney medulla protein composition measurement" EXACT [] is_a: CMO:0001180 ! renal medulla protein measurement is_a: CMO:0001182 ! calculated kidney protein composition measurement @@ -10176,7 +10176,7 @@ creation_date: 2012-10-23T10:05:50Z [Term] id: CMO:0001189 name: calculated middle cerebral artery inner diameter measurement -def: "The length of a line which crosses a transverse view of a middle cerebral artery, passing through its center and ending on either side at the inner surface of the blood vessel wall, after that measurement has been normalized or adjusted by a mathematical process or computation. The middle cerebral arteries are the largest of the cerebral arteries and supply blood to the lateral cerebral cortex, anterior temporal lobes and insular cortices of the brain." [RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Middle_cerebral_artery] +def: "The length of a line which crosses a transverse view of a middle cerebral artery, passing through its center and ending on either side at the inner surface of the blood vessel wall, after that measurement has been normalized or adjusted by a mathematical process or computation. The middle cerebral arteries are the largest of the cerebral arteries and supply blood to the lateral cerebral cortex, anterior temporal lobes and insular cortices of the brain." [RGD:JRS, https://en.wikipedia.org/wiki/Middle_cerebral_artery] is_a: CMO:0001128 ! middle cerebral artery inner diameter is_a: CMO:0001188 ! calculated cerebral artery inner diameter measurement created_by: JSmith @@ -10223,7 +10223,7 @@ creation_date: 2012-11-15T15:20:30Z [Term] id: CMO:0001194 name: white adipose tissue weight to body weight ratio -def: "A calculated value in which the weight of white adipose tissue, the thermal-insulating and energy-storing fat tissue of mammals, is divided by the total weight of the body and presented as a ratio, fraction, quotient or percent, thus normalizing it to body weight." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/White_adipose_tissue] +def: "A calculated value in which the weight of white adipose tissue, the thermal-insulating and energy-storing fat tissue of mammals, is divided by the total weight of the body and presented as a ratio, fraction, quotient or percent, thus normalizing it to body weight." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/White_adipose_tissue] synonym: "white fat weight to body weight ratio" EXACT [] is_a: CMO:0000312 ! calculated body fat morphological measurement created_by: JSmith @@ -10232,7 +10232,7 @@ creation_date: 2012-11-15T15:23:10Z [Term] id: CMO:0001195 name: epididymal plus perirenal white adipose tissue weight to body weight ratio -def: "A calculated value in which the sum of the weights of the white adipose tissue associated with the epididymus and that surrounding the kidneys is divided by the total weight of the body and presented as a ratio, fraction, quotient or percent, thus normalizing it to body weight." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/White_adipose_tissue] +def: "A calculated value in which the sum of the weights of the white adipose tissue associated with the epididymus and that surrounding the kidneys is divided by the total weight of the body and presented as a ratio, fraction, quotient or percent, thus normalizing it to body weight." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/White_adipose_tissue] synonym: "sum of epididymal and perirenal white adipose tissue to body weight ratio" EXACT [] is_a: CMO:0001194 ! white adipose tissue weight to body weight ratio created_by: JSmith @@ -10429,7 +10429,7 @@ creation_date: 2012-12-17T13:52:41Z [Term] id: CMO:0001218 name: frequency of pancreatic islet insulin release oscillations -def: "A measure of the frequency at which the basal levels of insulin secretion from the pancreatic islets oscillate or vary between alternate levels, i.e. higher and lower, within a definable period of time." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Insulin_oscillation] +def: "A measure of the frequency at which the basal levels of insulin secretion from the pancreatic islets oscillate or vary between alternate levels, i.e. higher and lower, within a definable period of time." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Insulin_oscillation] synonym: "pulsatile insulin release periodicity measurement" RELATED [] is_a: CMO:0001217 ! calculated pancreatic islet insulin release measurement created_by: JSmith @@ -10595,7 +10595,7 @@ creation_date: 2013-01-07T15:40:46Z [Term] id: CMO:0001237 name: renal sympathetic nerve activity measurement -def: "Assessment or quantification of the presence and/or amount of recordable electrical energy in a renal sympathetic nerve, a nerve of the autonomic nervous system that regulates involuntary and automatic reactions, especially to stress, associated with and controlling activity of the kidneys. A nerve is any of the cordlike structures that convey impulses between the central nervous system and one or more parts of the body, and that each consist of an outer connective tissue sheath surrounding a bundle of conductive fibers." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine_2008, ISBN:978-1416049982, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Sympathetic_nerve] +def: "Assessment or quantification of the presence and/or amount of recordable electrical energy in a renal sympathetic nerve, a nerve of the autonomic nervous system that regulates involuntary and automatic reactions, especially to stress, associated with and controlling activity of the kidneys. A nerve is any of the cordlike structures that convey impulses between the central nervous system and one or more parts of the body, and that each consist of an outer connective tissue sheath surrounding a bundle of conductive fibers." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine_2008, ISBN:978-1416049982, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, https://en.wikipedia.org/wiki/Sympathetic_nerve] synonym: "RSNA measurement" RELATED [] is_a: CMO:0001236 ! sympathetic nerve activity measurement created_by: JSmith @@ -10604,7 +10604,7 @@ creation_date: 2013-01-07T15:42:29Z [Term] id: CMO:0001238 name: change in renal sympathetic nerve activity to change in intracerebroventricular sodium concentration ratio -def: "A calculated measurement in which the change in the activity, i.e., the recordable electrical energy, of the renal sympathetic nerves between two points in time or two conditions is compared to the concentration of a solution of sodium, the chemical element with atomic number 11, infused directly into the ventricle(s) of the brain; calculated as the slope of the curve of renal sympathetic nerve activity versus intracerebroventricular-infused sodium concentration. A renal sympathetic nerve is a nerve (a cordlike structure that conveys impulses between the central nervous system and one or more parts of the body, and that consists of an outer connective tissue sheath surrounding a bundle of conductive fibers) of the autonomic nervous system that regulates involuntary and automatic reactions, especially to stress, associated with and controlling activity of the kidneys." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/, PMID:17420333, PMID:19558257, Wikipedia:http\://en.wikipedia.org/wiki/Sympathetic_nerve] +def: "A calculated measurement in which the change in the activity, i.e., the recordable electrical energy, of the renal sympathetic nerves between two points in time or two conditions is compared to the concentration of a solution of sodium, the chemical element with atomic number 11, infused directly into the ventricle(s) of the brain; calculated as the slope of the curve of renal sympathetic nerve activity versus intracerebroventricular-infused sodium concentration. A renal sympathetic nerve is a nerve (a cordlike structure that conveys impulses between the central nervous system and one or more parts of the body, and that consists of an outer connective tissue sheath surrounding a bundle of conductive fibers) of the autonomic nervous system that regulates involuntary and automatic reactions, especially to stress, associated with and controlling activity of the kidneys." [ISBN:978-1416049982, http://www.thefreedictionary.com/, PMID:17420333, PMID:19558257, https://en.wikipedia.org/wiki/Sympathetic_nerve] synonym: "change in RSNA to change in intracerebroventricular sodium concentration ratio" RELATED [] is_a: CMO:0001785 ! calculated renal sympathetic nerve activity measurement created_by: JSmith @@ -10729,7 +10729,7 @@ creation_date: 2013-01-08T14:10:17Z [Term] id: CMO:0001252 name: calculated inguinal fat pad weight -def: "A value which has been normalized, adjusted or derived by a mathematical process or computation for the heaviness or degree to which the inguinal fat pad, the accumulation of encapsulated adipose tissue located in the junctional region between the abdomen and thigh, is drawn toward the earth by gravity." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A value which has been normalized, adjusted or derived by a mathematical process or computation for the heaviness or degree to which the inguinal fat pad, the accumulation of encapsulated adipose tissue located in the junctional region between the abdomen and thigh, is drawn toward the earth by gravity." [http://www.thefreedictionary.com/] synonym: "Not4Curation" RELATED [] is_a: CMO:0001250 ! calculated body region fat morphological measurement is_a: CMO:0001637 ! inguinal fat pad weight @@ -10739,7 +10739,7 @@ creation_date: 2013-01-08T14:13:11Z [Term] id: CMO:0001253 name: inguinal fat pad weight to body weight ratio -def: "A calculated value in which the weight of one or both of the inguinal fat pads, that is, the accumulations of encapsulated adipose tissue located in the junctional region between the abdomen and thigh, is divided by the total weight of the body and presented as a ratio, fraction or quotient, thus normalizing it to body weight and, by extension, to the size of the organism." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated value in which the weight of one or both of the inguinal fat pads, that is, the accumulations of encapsulated adipose tissue located in the junctional region between the abdomen and thigh, is divided by the total weight of the body and presented as a ratio, fraction or quotient, thus normalizing it to body weight and, by extension, to the size of the organism." [http://www.thefreedictionary.com/] is_a: CMO:0001252 ! calculated inguinal fat pad weight created_by: JSmith creation_date: 2013-01-08T14:17:30Z @@ -10911,7 +10911,7 @@ creation_date: 2013-01-08T17:48:16Z [Term] id: CMO:0001272 name: plasma anti-type 2 collagen antibody level -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "plasma anti-type II collagen antibody level" EXACT [] is_a: CMO:0001271 ! plasma anti-collagen antibody level created_by: JSmith @@ -10920,7 +10920,7 @@ creation_date: 2013-01-08T17:58:30Z [Term] id: CMO:0001273 name: plasma anti-bovine type 2 collagen antibody level -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds cattle-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds cattle-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "plasma anti-bovine type II collagen antibody level" EXACT [] is_a: CMO:0001272 ! plasma anti-type 2 collagen antibody level created_by: JSmith @@ -10929,7 +10929,7 @@ creation_date: 2013-01-08T18:05:59Z [Term] id: CMO:0001274 name: plasma anti-porcine type 2 collagen antibody level -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "plasma anti-porcine type II collagen antibody level" EXACT [] is_a: CMO:0001272 ! plasma anti-type 2 collagen antibody level created_by: JSmith @@ -10938,7 +10938,7 @@ creation_date: 2013-01-08T18:11:21Z [Term] id: CMO:0001275 name: plasma anti-rat type 2 collagen antibody level -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds rat-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds rat-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "plasma anti-rat type II collagen antibody level" EXACT [] is_a: CMO:0001272 ! plasma anti-type 2 collagen antibody level created_by: JSmith @@ -10964,7 +10964,7 @@ creation_date: 2013-01-08T18:25:02Z [Term] id: CMO:0001278 name: calculated serum anti-porcine type 2 collagen antibody titer -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen in a specified sample of serum, when that measurement is based on, or uses in the calculation, the antibody titer. An antibody titer is the last dilution of a sample at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen in a specified sample of serum, when that measurement is based on, or uses in the calculation, the antibody titer. An antibody titer is the last dilution of a sample at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "calculated serum anti-porcine type II collagen antibody titer" EXACT [] synonym: "serum anti-porcine type 2 collagen antibody titer normalized for absorbance" RELATED [] is_a: CMO:0001279 ! calculated serum anti-type 2 collagen antibody titer @@ -10975,7 +10975,7 @@ creation_date: 2013-01-08T18:28:53Z [Term] id: CMO:0001279 name: calculated serum anti-type 2 collagen antibody titer -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen in a specified volume of serum, when that calculation is based on the antibody titer. A serum antibody titer is the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen in a specified volume of serum, when that calculation is based on the antibody titer. A serum antibody titer is the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "serum anti-type II collagen antibody titer normalized for absorbance" RELATED [] is_a: CMO:0002625 ! serum anti-type 2 collagen antibody titer created_by: JSmith @@ -10993,7 +10993,7 @@ creation_date: 2013-01-08T18:28:53Z [Term] id: CMO:0001281 name: calculated serum anti-rat type 2 collagen autoantibody titer -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of rat type 2 collagen autoantibody in a specified sample of serum, when the caluculation is based on the autoantibody titer. A serum autoantibody titer is the last dilution of serum at which a positive result could be obtained for an antibody that attacks the cells, tissues, native proteins, or other endogenous molecules of the organism in which it was formed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of rat type 2 collagen autoantibody in a specified sample of serum, when the caluculation is based on the autoantibody titer. A serum autoantibody titer is the last dilution of serum at which a positive result could be obtained for an antibody that attacks the cells, tissues, native proteins, or other endogenous molecules of the organism in which it was formed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "calculated rat serum anti-self type 2 collagen autoantibody titer" EXACT [] synonym: "calculated serum anti-rat type II collagen autoantibody titer" EXACT [] synonym: "serum anti-rat type 2 collagen autoantibody titer normalized for absorbance" RELATED [] @@ -11005,7 +11005,7 @@ creation_date: 2013-01-08T18:28:53Z [Term] id: CMO:0001282 name: serum anti-bovine type 2 collagen antibody level -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds cattle-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds cattle-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "serum anti-bovine type II collagen antibody level" EXACT [] is_a: CMO:0002627 ! serum anti-type 2 collagen antibody level created_by: JSmith @@ -11021,7 +11021,7 @@ creation_date: 2013-01-09T11:31:04Z [Term] id: CMO:0001284 name: blood troponin T level -def: "The amount in a specified volume of whole blood of troponin T, one subunit of a complex of three regulatory proteins required for skeletal and cardiac muscle contraction; used as an indicator for myocardial damage." [Wikipedia:http\://en.wikipedia.org/wiki/Troponin_T] +def: "The amount in a specified volume of whole blood of troponin T, one subunit of a complex of three regulatory proteins required for skeletal and cardiac muscle contraction; used as an indicator for myocardial damage." [https://en.wikipedia.org/wiki/Troponin_T] is_a: CMO:0001283 ! blood troponin level created_by: JSmith creation_date: 2013-01-09T11:33:20Z @@ -11029,7 +11029,7 @@ creation_date: 2013-01-09T11:33:20Z [Term] id: CMO:0001285 name: serum troponin T level -def: "The amount of troponin T, one subunit of a complex of three regulatory proteins required for skeletal and cardiac muscle contraction in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Troponin_T] +def: "The amount of troponin T, one subunit of a complex of three regulatory proteins required for skeletal and cardiac muscle contraction in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Troponin_T] is_a: CMO:0001284 ! blood troponin T level created_by: JSmith creation_date: 2013-01-09T11:35:58Z @@ -11037,7 +11037,7 @@ creation_date: 2013-01-09T11:35:58Z [Term] id: CMO:0001286 name: plasma troponin T level -def: "The amount of troponin T, one subunit of a complex of three regulatory proteins required for skeletal and cardiac muscle contraction in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Troponin_T] +def: "The amount of troponin T, one subunit of a complex of three regulatory proteins required for skeletal and cardiac muscle contraction in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Troponin_T] is_a: CMO:0001284 ! blood troponin T level created_by: JSmith creation_date: 2013-01-09T11:36:24Z @@ -11045,7 +11045,7 @@ creation_date: 2013-01-09T11:36:24Z [Term] id: CMO:0001287 name: blood thyroid hormone level -def: "The amount of one or more thyroid hormones, that is, hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism, in a specified volume of blood." [Wikipedia:http\://en.wikipedia.org/wiki/Thyroid_hormone] +def: "The amount of one or more thyroid hormones, that is, hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism, in a specified volume of blood." [https://en.wikipedia.org/wiki/Thyroid_hormone] is_a: CMO:0001005 ! blood monoamine hormone level created_by: JSmith creation_date: 2013-01-09T11:44:11Z @@ -11053,7 +11053,7 @@ creation_date: 2013-01-09T11:44:11Z [Term] id: CMO:0001288 name: blood thyroxine level -def: "The amount of thyroxine, the major hormone derived from the thyroid gland which regulates cellular metabolism, in a specified volume of blood." [Wikipedia:http\://en.wikipedia.org/wiki/Thyroxine] +def: "The amount of thyroxine, the major hormone derived from the thyroid gland which regulates cellular metabolism, in a specified volume of blood." [https://en.wikipedia.org/wiki/Thyroxine] synonym: "blood T4 level" RELATED [] is_a: CMO:0001287 ! blood thyroid hormone level created_by: JSmith @@ -11062,7 +11062,7 @@ creation_date: 2013-01-09T11:48:05Z [Term] id: CMO:0001289 name: plasma thyroxine level -def: "The amount of thyroxine, the major hormone derived from the thyroid gland which regulates cellular metabolism, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Thyroxine] +def: "The amount of thyroxine, the major hormone derived from the thyroid gland which regulates cellular metabolism, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Thyroxine] synonym: "plasma T4 level" RELATED [] is_a: CMO:0001288 ! blood thyroxine level created_by: JSmith @@ -11071,7 +11071,7 @@ creation_date: 2013-01-09T11:51:11Z [Term] id: CMO:0001290 name: serum thyroxine level -def: "The amount of thyroxine, the major hormone derived from the thyroid gland which regulates cellular metabolism, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Thyroxine] +def: "The amount of thyroxine, the major hormone derived from the thyroid gland which regulates cellular metabolism, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Thyroxine] synonym: "serum T4 level" RELATED [] is_a: CMO:0001288 ! blood thyroxine level created_by: JSmith @@ -11080,7 +11080,7 @@ creation_date: 2013-01-09T11:51:20Z [Term] id: CMO:0001291 name: blood triiodothyronine level -def: "The amount of triiodothyronine, a hormone synthesized and secreted by the thyroid which constitutes the main thyroid hormone used by the tissues, in a specified volume of blood." [Wikipedia:http\://en.wikipedia.org/wiki/Triiodothyronine] +def: "The amount of triiodothyronine, a hormone synthesized and secreted by the thyroid which constitutes the main thyroid hormone used by the tissues, in a specified volume of blood." [https://en.wikipedia.org/wiki/Triiodothyronine] synonym: "blood T3 level" RELATED [] is_a: CMO:0001287 ! blood thyroid hormone level created_by: JSmith @@ -11089,7 +11089,7 @@ creation_date: 2013-01-09T11:54:14Z [Term] id: CMO:0001292 name: plasma triiodothyronine level -def: "The amount of triiodothyronine, a hormone synthesized and secreted by the thyroid which constitutes the main thyroid hormone used by the tissues, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Triiodothyronine] +def: "The amount of triiodothyronine, a hormone synthesized and secreted by the thyroid which constitutes the main thyroid hormone used by the tissues, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Triiodothyronine] synonym: "plasma T3 level" RELATED [] is_a: CMO:0001291 ! blood triiodothyronine level created_by: JSmith @@ -11098,7 +11098,7 @@ creation_date: 2013-01-09T11:57:55Z [Term] id: CMO:0001293 name: serum triiodothyronine level -def: "The amount of triiodothyronine, a hormone synthesized and secreted by the thyroid which constitutes the main thyroid hormone used by the tissues, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Triiodothyronine] +def: "The amount of triiodothyronine, a hormone synthesized and secreted by the thyroid which constitutes the main thyroid hormone used by the tissues, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Triiodothyronine] synonym: "serum T3 level" RELATED [] is_a: CMO:0001291 ! blood triiodothyronine level created_by: JSmith @@ -11639,7 +11639,7 @@ creation_date: 2013-01-10T17:31:25Z [Term] id: CMO:0001357 name: red blood cell Na+/K+ ATPase activity -def: "The level of activity of any of the sodium-potassium adenosine triphosphatases, enzymes which catalyze the active, ATP-dependent transport of sodium and potassium ions across cell membranes, in a specified volume of red blood cells." [Wikipedia:http\://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase] +def: "The level of activity of any of the sodium-potassium adenosine triphosphatases, enzymes which catalyze the active, ATP-dependent transport of sodium and potassium ions across cell membranes, in a specified volume of red blood cells." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase] synonym: "red blood cell sodium/potassium ATPase activity" EXACT [] synonym: "red blood cell sodium-potassium adenosine triphosphatase activity" EXACT [] is_a: CMO:0003103 ! red blood cell physiological measurement @@ -11666,7 +11666,7 @@ creation_date: 2013-01-10T18:04:59Z [Term] id: CMO:0001360 name: calculated blood thyroid hormone level -def: "A measurement of one or more thyroid hormones, the hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism, which has been normalized, adjusted or derived by a mathematical process or computation." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Thyroid_hormone] +def: "A measurement of one or more thyroid hormones, the hormones produced by the thyroid gland that are primarily responsible for regulation of metabolism, which has been normalized, adjusted or derived by a mathematical process or computation." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Thyroid_hormone] is_a: CMO:0001287 ! blood thyroid hormone level created_by: JSmith creation_date: 2013-01-11T11:24:02Z @@ -11721,7 +11721,7 @@ creation_date: 2013-01-11T11:58:22Z [Term] id: CMO:0001366 name: horn morphological measurement -def: "Any measurement of the physical form or structure of one or more horns of an animal. A horn is a usually pointed projection of skin on the head of various animals consisting of a covering of keratin and other proteins surrounding a core of live bone." [Wikipedia:http\://en.wikipedia.org/wiki/Horn_%28anatomy%29] +def: "Any measurement of the physical form or structure of one or more horns of an animal. A horn is a usually pointed projection of skin on the head of various animals consisting of a covering of keratin and other proteins surrounding a core of live bone." [https://en.wikipedia.org/wiki/Horn_%28anatomy%29] is_a: CMO:0000443 ! bone morphological measurement is_a: CMO:0001368 ! skin morphological measurement created_by: JSmith @@ -11953,7 +11953,7 @@ creation_date: 2013-01-11T17:56:52Z [Term] id: CMO:0001393 name: milk palmitoleic to palmitic acid ratio -def: "A calculated measurement in which the amount in milk fat of the 16 carbon monounsaturated fatty acid palmitoleic acid is divided by the amount of the 16 carbon saturated fatty acid palmitic acid and expressed as a percentage." [RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Fatty_acid] +def: "A calculated measurement in which the amount in milk fat of the 16 carbon monounsaturated fatty acid palmitoleic acid is divided by the amount of the 16 carbon saturated fatty acid palmitic acid and expressed as a percentage." [RGD:JRS, https://en.wikipedia.org/wiki/Fatty_acid] is_a: CMO:0000817 ! milk fatty acid measurement created_by: JSmith creation_date: 2013-01-11T18:01:14Z @@ -11961,7 +11961,7 @@ creation_date: 2013-01-11T18:01:14Z [Term] id: CMO:0001394 name: longissimus muscle weight -def: "The weight or the measure of the heaviness of the longissimus muscle of the back. The longissimus is the longest subdivision of the sacrospinalis located lateral to the semispinalis and extends forward into the transverse processes of the posterior cervical vertebrae." [Wikipedia:http\://en.wikipedia.org/wiki/Longissimus] +def: "The weight or the measure of the heaviness of the longissimus muscle of the back. The longissimus is the longest subdivision of the sacrospinalis located lateral to the semispinalis and extends forward into the transverse processes of the posterior cervical vertebrae." [https://en.wikipedia.org/wiki/Longissimus] is_a: CMO:0001148 ! skeletal muscle weight created_by: JSmith creation_date: 2013-01-14T11:32:03Z @@ -12017,7 +12017,7 @@ creation_date: 2013-01-14T12:54:50Z [Term] id: CMO:0001401 name: relapsing-remitting experimental autoimmune encephalomyelitis incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) at a point in time or develop R-EAE within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. Relapsing-remitting EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "Any measurement in which the number of individuals in a study population that display relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) at a point in time or develop R-EAE within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. Relapsing-remitting EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "R-EAE incidence/prevalence measurement" RELATED [] synonym: "relapsing/remitting experimental autoimmune encephalomyelitis incidence/prevalence measurement" RELATED [] synonym: "relapsing-remitting EAE incidence/prevalence measurement" RELATED [] @@ -12028,7 +12028,7 @@ creation_date: 2013-01-14T13:01:24Z [Term] id: CMO:0001402 name: percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time -def: "The number of new cases of relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. R-EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of new cases of relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. R-EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "percentage of study population developing relapsing/remitting experimental autoimmune encephalomyelitis during a period of time" EXACT [] synonym: "R-EAE incidence" RELATED [] synonym: "relapsing-remitting EAE incidence" RELATED [] @@ -12041,7 +12041,7 @@ creation_date: 2013-01-14T13:40:33Z [Term] id: CMO:0001403 name: percentage of study population displaying relapsing-remitting experimental autoimmune encephalomyelitis at a point in time -def: "The number of individuals in a study population which display relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. R-EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of individuals in a study population which display relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. R-EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "percentage of study population displaying relapsing/remitting experimental autoimmune encephalomyelitis at a point in time" EXACT [] synonym: "R-EAE prevalence" RELATED [] synonym: "relapsing-remitting EAE prevalence" RELATED [] @@ -12146,7 +12146,7 @@ creation_date: 2013-01-15T11:34:35Z [Term] id: CMO:0001414 name: artery neointimal hyperplastic lesion area -def: "A measurement of the extent of a two-dimensional surface of or plane through a single hyperplastic lesion of the tunica intima, that is, the inner coat of the arterial wall, or a measurement of the total area occupied by hyperplastic lesions of the tunica intima in a cross-section of an artery, one of the large blood vessels carrying blood in a direction away from the heart to the tissues. A hyperplastic lesion is a localized pathological increase in the number of cells of an organ or tissue resulting from an increased rate of cellular division due to injury or disease; especially one that is circumscribed and well defined." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Intimal_hyperplasia] +def: "A measurement of the extent of a two-dimensional surface of or plane through a single hyperplastic lesion of the tunica intima, that is, the inner coat of the arterial wall, or a measurement of the total area occupied by hyperplastic lesions of the tunica intima in a cross-section of an artery, one of the large blood vessels carrying blood in a direction away from the heart to the tissues. A hyperplastic lesion is a localized pathological increase in the number of cells of an organ or tissue resulting from an increased rate of cellular division due to injury or disease; especially one that is circumscribed and well defined." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Intimal_hyperplasia] synonym: "artery intimal hyperplastic lesion area" RELATED [] synonym: "neointimal hyperplasia area of artery" RELATED [] is_a: CMO:0000975 ! artery lesion measurement @@ -12184,7 +12184,7 @@ creation_date: 2013-01-15T12:50:46Z [Term] id: CMO:0001418 name: experimental autoimmune encephalomyelitis severity measurement -def: "Any measurement of the degree to which the presentation of the experimental autoimmune encephalomyelitis disease state, i.e. the animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells, causes pain or damage." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "Any measurement of the degree to which the presentation of the experimental autoimmune encephalomyelitis disease state, i.e. the animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells, causes pain or damage." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "EAE severity measurement" RELATED [] synonym: "Not4Curation" RELATED [] is_a: CMO:0001109 ! disease severity measurement @@ -12194,7 +12194,7 @@ creation_date: 2013-01-15T12:54:47Z [Term] id: CMO:0001419 name: experimental autoimmune encephalomyelitis severity score -def: "A rating, usually expressed numerically and based on the degree to which certain qualities or conditions are present, of the degree to which the presentation of the experimental autoimmune encephalomyelitis disease state, i.e. the animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells, causes pain or damage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "A rating, usually expressed numerically and based on the degree to which certain qualities or conditions are present, of the degree to which the presentation of the experimental autoimmune encephalomyelitis disease state, i.e. the animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells, causes pain or damage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "EAE severity score" RELATED [] is_a: CMO:0001418 ! experimental autoimmune encephalomyelitis severity measurement created_by: JSmith @@ -12233,7 +12233,7 @@ creation_date: 2013-01-15T14:09:41Z [Term] id: CMO:0001423 name: experimental autoimmune encephalomyelitis progression measurement -def: "Any measurement related to the course of experimental autoimmune encephalomyelitis (EAE), an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells, for example, a series of stages or a succession of states in the disease process or the duration of the disease state." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "Any measurement related to the course of experimental autoimmune encephalomyelitis (EAE), an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells, for example, a series of stages or a succession of states in the disease process or the duration of the disease state." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "EAE progression measurement" RELATED [] is_a: CMO:0001110 ! disease progression measurement created_by: JSmith @@ -12242,7 +12242,7 @@ creation_date: 2013-01-15T14:12:37Z [Term] id: CMO:0001424 name: experimental autoimmune encephalomyelitis duration -def: "Measurement of the length of time between onset of experimental autoimmune encephalomyelitis (EAE), an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells, and either the point at which the measurement is taken, the resolution of symptoms or the death of the organism." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "Measurement of the length of time between onset of experimental autoimmune encephalomyelitis (EAE), an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells, and either the point at which the measurement is taken, the resolution of symptoms or the death of the organism." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "EAE duration" RELATED [] is_a: CMO:0001423 ! experimental autoimmune encephalomyelitis progression measurement created_by: JSmith @@ -12346,7 +12346,7 @@ creation_date: 2013-01-16T16:39:24Z [Term] id: CMO:0001436 name: inflammatory exudate nitric oxide level -def: "Measurement of the amount of nitric oxide (NO), the free radical oxide of nitrogen which functions in various physiological capacities including as a vasodilator, signaling molecule, neurotransmitter and microbicide, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation, a usually localized, protective reaction of tissue to irritation, injury or infection, characterized by pain, redness, swelling and sometimes loss of function." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Nitric_Oxide] +def: "Measurement of the amount of nitric oxide (NO), the free radical oxide of nitrogen which functions in various physiological capacities including as a vasodilator, signaling molecule, neurotransmitter and microbicide, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation, a usually localized, protective reaction of tissue to irritation, injury or infection, characterized by pain, redness, swelling and sometimes loss of function." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Nitric_Oxide] synonym: "inflammatory exudate NO level" EXACT [] xref: CHEBI:16480 is_a: CMO:0001428 ! inflammatory exudate measurement @@ -12356,7 +12356,7 @@ creation_date: 2013-01-16T16:42:59Z [Term] id: CMO:0001437 name: inflammatory exudate eicosanoid measurement -def: "Measurement of the amount of one or more eicosanoids, physiologically active molecules derived by oxidation of twenty-carbon essential fatty acids such as arachidonic acid, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation, a usually localized, protective reaction of tissue to irritation, injury or infection, characterized by pain, redness, swelling and sometimes loss of function." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Eicosanoid] +def: "Measurement of the amount of one or more eicosanoids, physiologically active molecules derived by oxidation of twenty-carbon essential fatty acids such as arachidonic acid, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation, a usually localized, protective reaction of tissue to irritation, injury or infection, characterized by pain, redness, swelling and sometimes loss of function." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Eicosanoid] synonym: "inflammatory exudate icosanoid measurement" EXACT [] is_a: CMO:0001428 ! inflammatory exudate measurement created_by: JSmith @@ -12365,7 +12365,7 @@ creation_date: 2013-01-17T10:27:16Z [Term] id: CMO:0001438 name: inflammatory exudate leukotriene B4 level -def: "Measurement of the amount of leukotriene B4, a major metabolite in neutrophils which stimulates degranulation, formation of oxygen-centered free radicals, and arachidonic acid and lysosome release, and serves as a potent chemoattractant, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, MeSH:D007975, Wikipedia:http\://en.wikipedia.org/wiki/Leukotriene_B4] +def: "Measurement of the amount of leukotriene B4, a major metabolite in neutrophils which stimulates degranulation, formation of oxygen-centered free radicals, and arachidonic acid and lysosome release, and serves as a potent chemoattractant, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, MeSH:D007975, https://en.wikipedia.org/wiki/Leukotriene_B4] synonym: "inflammatory exudate LTB4 level" EXACT [] is_a: CMO:0001437 ! inflammatory exudate eicosanoid measurement created_by: JSmith @@ -12374,7 +12374,7 @@ creation_date: 2013-01-17T10:37:02Z [Term] id: CMO:0001439 name: inflammatory exudate lipoxin A4 level -def: "Measurement of the amount of lipoxin A4, a arachidonic acid-derived nonclassic eicosanoid which participates in the resolution of inflammation, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Lipoxin_A4] +def: "Measurement of the amount of lipoxin A4, a arachidonic acid-derived nonclassic eicosanoid which participates in the resolution of inflammation, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Lipoxin_A4] synonym: "inflammatory exudate LXA4 level" EXACT [] is_a: CMO:0001437 ! inflammatory exudate eicosanoid measurement created_by: JSmith @@ -12383,7 +12383,7 @@ creation_date: 2013-01-17T11:01:46Z [Term] id: CMO:0001440 name: calculated inflammatory exudate eicosanoid measurement -def: "A measurement which has been normalized, adjusted or derived by a mathematical process, of the amount of one or more eicosanoids, physiologically active molecules derived by oxidation of twenty-carbon essential fatty acids such as arachidonic acid, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Eicosanoid] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process, of the amount of one or more eicosanoids, physiologically active molecules derived by oxidation of twenty-carbon essential fatty acids such as arachidonic acid, in a specified volume of fluid which has escaped from blood vessels and been deposited within tissues or on tissue surfaces as a result of inflammation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Eicosanoid] synonym: "calculated inflammatory exudate icosanoid measurement" EXACT [] is_a: CMO:0001437 ! inflammatory exudate eicosanoid measurement created_by: JSmith @@ -12401,7 +12401,7 @@ creation_date: 2013-01-17T11:14:00Z [Term] id: CMO:0001442 name: measurement of voluntary horizontal locomotion in an experimental apparatus -def: "Any measurement of the movement of an organism from one place to another along a plane parallel to the plane of the horizon in a piece of technical equipment or machinery, or in an appliance or device designed for a particular purpose (especially such a movement accomplished by the action of appendages such as flagella, limbs, or wings) originated, undertaken, controlled, or accomplished as a result of free will or choice." [Multiple_Dictionaries:http\://www.thefreedictionary.com/horizontal] +def: "Any measurement of the movement of an organism from one place to another along a plane parallel to the plane of the horizon in a piece of technical equipment or machinery, or in an appliance or device designed for a particular purpose (especially such a movement accomplished by the action of appendages such as flagella, limbs, or wings) originated, undertaken, controlled, or accomplished as a result of free will or choice." [http://www.thefreedictionary.com/horizontal] is_a: CMO:0000956 ! measurement of voluntary locomotion in an experimental apparatus created_by: JSmith creation_date: 2013-01-17T11:23:46Z @@ -12409,7 +12409,7 @@ creation_date: 2013-01-17T11:23:46Z [Term] id: CMO:0001443 name: total horizontal distance resulting from voluntary locomotion in an experimental apparatus -def: "Measurement of the linear equivalent of the extent of forward progress attained via the movement of an individual along a plane parallel to the plane of the horizon in a piece of technical equipment or machinery, or in an appliance or device designed for a particular purpose originated, undertaken, controlled, or accomplished as a result of free will or choice." [Multiple_Dictionaries:http\://www.thefreedictionary.com/horizontal] +def: "Measurement of the linear equivalent of the extent of forward progress attained via the movement of an individual along a plane parallel to the plane of the horizon in a piece of technical equipment or machinery, or in an appliance or device designed for a particular purpose originated, undertaken, controlled, or accomplished as a result of free will or choice." [http://www.thefreedictionary.com/horizontal] synonym: "total horizontal distance travelled in an experimental apparatus" RELATED [] is_a: CMO:0001442 ! measurement of voluntary horizontal locomotion in an experimental apparatus created_by: JSmith @@ -12434,7 +12434,7 @@ creation_date: 2013-01-17T12:11:09Z [Term] id: CMO:0001446 name: absolute change in adipocyte free fatty acid secretion per unit volume -def: "The difference, reported per unit volume, in the amount of free or non-esterified fatty acid released/secreted from a fat cell between two conditions, for example between the basal or baseline state and a stimulated state, such as occurs with administration of a hormone which stimulates lipolysis." [Multiple_Dictionaries:http\://www.thefreedictionary.com/horizontal] +def: "The difference, reported per unit volume, in the amount of free or non-esterified fatty acid released/secreted from a fat cell between two conditions, for example between the basal or baseline state and a stimulated state, such as occurs with administration of a hormone which stimulates lipolysis." [http://www.thefreedictionary.com/horizontal] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in adipocyte free fatty acid release per unit volume" EXACT [] synonym: "absolute change in adipocyte NEFA release per unit volume" RELATED [] @@ -12451,7 +12451,7 @@ creation_date: 2013-01-17T12:28:28Z [Term] id: CMO:0001447 name: absolute change in adipocyte free fatty acid secretion per cell -def: "The difference, reported per cell, in the amount of free or non-esterified fatty acid released/secreted from a fat cell between two conditions, for example between the basal or baseline state and a stimulated state, such as occurs with administration of a hormone which stimulates lipolysis." [Multiple_Dictionaries:http\://www.thefreedictionary.com/horizontal] +def: "The difference, reported per cell, in the amount of free or non-esterified fatty acid released/secreted from a fat cell between two conditions, for example between the basal or baseline state and a stimulated state, such as occurs with administration of a hormone which stimulates lipolysis." [http://www.thefreedictionary.com/horizontal] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in adipocyte free fatty acid release per cell" EXACT [] synonym: "absolute change in adipocyte NEFA release per cell" RELATED [] @@ -12777,7 +12777,7 @@ creation_date: 2013-01-25T13:21:50Z [Term] id: CMO:0001482 name: heart isovolumetric relaxation time -def: "The length of time in the cardiac cycle between the closing of the aortic and pulmonic/pulmonary semilunar valves and opening of the atrioventricular (AV) valves marking the beginning of ventricular filling. Used as an indicator of diastolic dysfunction." [Mondofacto:Mondofacto_Online_Medical_Dictionary, Website:http\://www.cvphysiology.com/Heart%20Disease/HD002e.htm, Website:http\://www.elu.sgul.ac.uk/rehash/guest/scorm/383/package/content/cardiac_cycle.htm] +def: "The length of time in the cardiac cycle between the closing of the aortic and pulmonic/pulmonary semilunar valves and opening of the atrioventricular (AV) valves marking the beginning of ventricular filling. Used as an indicator of diastolic dysfunction." [Mondofacto:Mondofacto_Online_Medical_Dictionary, http://www.cvphysiology.com/Heart%20Disease/HD002e.htm, http://www.elu.sgul.ac.uk/rehash/guest/scorm/383/package/content/cardiac_cycle.htm] synonym: "IVRT" RELATED [] is_a: CMO:0000662 ! heart contraction measurement created_by: JSmith @@ -12818,7 +12818,7 @@ creation_date: 2013-01-25T15:50:33Z [Term] id: CMO:0001487 name: calculated heart left atrium morphological measurement -def: "A measurement of the physical form or structure of the left atrium, the left upper chamber of the heart that receives blood from the veins and forces it into the left ventricle, which has been normalized, adjusted or derived by a mathematical process or computation." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the physical form or structure of the left atrium, the left upper chamber of the heart that receives blood from the veins and forces it into the left ventricle, which has been normalized, adjusted or derived by a mathematical process or computation." [http://www.thefreedictionary.com/] is_a: CMO:0001483 ! heart left atrium morphological measurement created_by: JSmith creation_date: 2013-01-25T15:51:30Z @@ -12826,7 +12826,7 @@ creation_date: 2013-01-25T15:51:30Z [Term] id: CMO:0001488 name: heart left atrium fractional shortening -def: "A calculated measurement corresponding to the ratio or percent reduction in left atrial diameter between end-systole and end-diastole. It is calculated as the left atrium end-systolic diameter (LADs) minus the left atrium end-diastolic diameter (LADd) divided by the left atrium end-systolic diameter (LADs)." [PMID:18806617, Wikipedia:http\://en.wikipedia.org/wiki/Ventricle_%28heart%29] +def: "A calculated measurement corresponding to the ratio or percent reduction in left atrial diameter between end-systole and end-diastole. It is calculated as the left atrium end-systolic diameter (LADs) minus the left atrium end-diastolic diameter (LADd) divided by the left atrium end-systolic diameter (LADs)." [PMID:18806617, https://en.wikipedia.org/wiki/Ventricle_%28heart%29] is_a: CMO:0001487 ! calculated heart left atrium morphological measurement created_by: JSmith creation_date: 2013-01-25T16:00:18Z @@ -12834,7 +12834,7 @@ creation_date: 2013-01-25T16:00:18Z [Term] id: CMO:0001489 name: joint mobility measurement -def: "Any measurement of the ease with which a joint, that is, an articulation where two bones meet, or series of joints is able to move before being restricted by the surrounding structures, such as ligaments, tendons, muscles, etc." [Oxford:Oxford_Food_&_Fitness_Dictionary_2003, Website:http\://www.acefitness.org/blog/1189/stability-and-mobility] +def: "Any measurement of the ease with which a joint, that is, an articulation where two bones meet, or series of joints is able to move before being restricted by the surrounding structures, such as ligaments, tendons, muscles, etc." [Oxford:Oxford_Food_&_Fitness_Dictionary_2003, http://www.acefitness.org/blog/1189/stability-and-mobility] is_a: CMO:0000917 ! joint measurement created_by: JSmith creation_date: 2013-01-25T16:10:53Z @@ -12869,7 +12869,7 @@ creation_date: 2013-01-25T17:59:53Z [Term] id: CMO:0001493 name: distance moved per unit of time into, out of or within a discrete space in an experimental apparatus -def: "Measurement of the linear equivalent of the extent of forward progress attained via the movement of an individual during a specified period of time into, out of or within a distinct and specified area of an experimental apparatus when such movement originated and/or was undertaken, controlled, or accomplished as a result of free will or choice." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of the linear equivalent of the extent of forward progress attained via the movement of an individual during a specified period of time into, out of or within a distinct and specified area of an experimental apparatus when such movement originated and/or was undertaken, controlled, or accomplished as a result of free will or choice." [http://www.thefreedictionary.com/] synonym: "measurement of distance moved per unit of time in an experimental apparatus" RELATED [] is_a: CMO:0000957 ! measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus created_by: JSmith @@ -13168,7 +13168,7 @@ creation_date: 2013-01-30T10:20:37Z [Term] id: CMO:0001525 name: age of onset of experimental autoimmune neuritis -def: "A measurement of the chronological age, that is, the length of time since birth, of the individual when the symptoms of experimental autoimmune neuritis (EAN), inflammation of peripheral nerves caused by an anti-self immune reaction experimentally or artificially triggered by introduction of peripheral nerve tissue or protein components in adjuvant, first appeared." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the chronological age, that is, the length of time since birth, of the individual when the symptoms of experimental autoimmune neuritis (EAN), inflammation of peripheral nerves caused by an anti-self immune reaction experimentally or artificially triggered by introduction of peripheral nerve tissue or protein components in adjuvant, first appeared." [http://www.thefreedictionary.com/] synonym: "age of onset of EAN" RELATED [] synonym: "age of onset of experimental allergic neuritis" EXACT [] is_a: CMO:0001524 ! experimental autoimmune neuritis onset/diagnosis measurement @@ -13178,7 +13178,7 @@ creation_date: 2013-01-30T10:22:33Z [Term] id: CMO:0001526 name: post-insult time to onset of experimental autoimmune neuritis -def: "Measurement of the length of time between introduction of a disease-producing stimulus to the observation of symptoms of experimental autoimmune neuritis (EAN), inflammation of peripheral nerves caused by an anti-self immune reaction experimentally or artificially triggered by introduction of peripheral nerve tissue or protein components in adjuvant." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Measurement of the length of time between introduction of a disease-producing stimulus to the observation of symptoms of experimental autoimmune neuritis (EAN), inflammation of peripheral nerves caused by an anti-self immune reaction experimentally or artificially triggered by introduction of peripheral nerve tissue or protein components in adjuvant." [http://www.thefreedictionary.com/] synonym: "post-immunization time to onset of EAN" RELATED [] synonym: "post-immunization time to onset of experimental autoimmune neuritis" RELATED [] synonym: "post-insult time to onset of EAN" RELATED [] @@ -13475,7 +13475,7 @@ creation_date: 2013-05-07T17:54:05Z [Term] id: CMO:0001558 name: bone polar moment of inertia -def: "A calculated geometric property of a cross section of a bone which expresses the inherent rotational stiffness of the bone. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, Website:http\://www.ah-engr.com/som/animations/polar_moment.html] +def: "A calculated geometric property of a cross section of a bone which expresses the inherent rotational stiffness of the bone. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, http://www.ah-engr.com/som/animations/polar_moment.html] synonym: "bone area moment of inertia" RELATED [] synonym: "bone cross-sectional moment of inertia" RELATED [] synonym: "bone Ip" RELATED [] @@ -13494,7 +13494,7 @@ creation_date: 2013-05-07T00:00:00Z [Term] id: CMO:0001560 name: bone polar moment of inertia to body weight ratio -def: "A calculated measurement in which the value of the polar moment of inertia is divided by the total weight or heaviness of the body and presented as a ratio, fraction, quotient or percentage, thus normalizing it to body weight. Polar moment of inertia is a calculated geometric property of a cross section of a bone which expresses the inherent rotational stiffness of the bone. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, Website:http\://www.ah-engr.com/som/animations/polar_moment.html] +def: "A calculated measurement in which the value of the polar moment of inertia is divided by the total weight or heaviness of the body and presented as a ratio, fraction, quotient or percentage, thus normalizing it to body weight. Polar moment of inertia is a calculated geometric property of a cross section of a bone which expresses the inherent rotational stiffness of the bone. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, http://www.ah-engr.com/som/animations/polar_moment.html] is_a: CMO:0001558 ! bone polar moment of inertia created_by: JSmith creation_date: 2013-05-07T18:42:39Z @@ -13511,7 +13511,7 @@ creation_date: 2013-05-07T18:45:42Z [Term] id: CMO:0001562 name: blood intermediate density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "blood IDL-C level" RELATED [] synonym: "blood IDL level" RELATED [] @@ -13522,7 +13522,7 @@ creation_date: 2013-05-08T11:08:21Z [Term] id: CMO:0001563 name: plasma intermediate density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "plasma IDL-C level" RELATED [] synonym: "plasma IDL level" RELATED [] @@ -13534,7 +13534,7 @@ creation_date: 2013-05-08T11:09:43Z [Term] id: CMO:0001564 name: serum intermediate density lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "serum IDL-C level" RELATED [] synonym: "serum IDL level" RELATED [] @@ -13546,7 +13546,7 @@ creation_date: 2013-05-08T11:11:20Z [Term] id: CMO:0001565 name: blood high density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in high-density lipoprotein (HDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in high-density lipoprotein (HDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "blood HDL phospholipid level" RELATED [] is_a: CMO:0001169 ! blood phospholipid level @@ -13557,7 +13557,7 @@ creation_date: 2013-05-08T12:50:31Z [Term] id: CMO:0001566 name: plasma high density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in high-density lipoprotein (HDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in high-density lipoprotein (HDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "plasma HDL phospholipid level" RELATED [] is_a: CMO:0001170 ! plasma phospholipid level @@ -13568,7 +13568,7 @@ creation_date: 2013-05-08T12:53:09Z [Term] id: CMO:0001567 name: serum high density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in high-density lipoprotein (HDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in high-density lipoprotein (HDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "serum HDL phospholipid level" RELATED [] is_a: CMO:0001171 ! serum phospholipid level @@ -13579,7 +13579,7 @@ creation_date: 2013-05-08T12:54:24Z [Term] id: CMO:0001568 name: blood low density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in low-density lipoprotein (LDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [BioMedCentral:http\://www.biomedcentral.com/1746-6148/9/47, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in low-density lipoprotein (LDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [http://www.biomedcentral.com/1746-6148/9/47, http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "blood LDL phospholipid level" RELATED [] is_a: CMO:0001169 ! blood phospholipid level @@ -13590,7 +13590,7 @@ creation_date: 2013-05-08T12:59:11Z [Term] id: CMO:0001569 name: plasma low density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in low-density lipoprotein (LDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [BioMedCentral:http\://www.biomedcentral.com/1746-6148/9/47, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in low-density lipoprotein (LDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [http://www.biomedcentral.com/1746-6148/9/47, http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "plasma LDL phospholipid level" RELATED [] is_a: CMO:0001170 ! plasma phospholipid level @@ -13601,7 +13601,7 @@ creation_date: 2013-05-08T13:01:48Z [Term] id: CMO:0001570 name: serum low density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in low-density lipoprotein (LDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [BioMedCentral:http\://www.biomedcentral.com/1746-6148/9/47, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in low-density lipoprotein (LDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [http://www.biomedcentral.com/1746-6148/9/47, http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "serum LDL phospholipid level" RELATED [] is_a: CMO:0001171 ! serum phospholipid level @@ -13612,7 +13612,7 @@ creation_date: 2013-05-08T13:02:56Z [Term] id: CMO:0001571 name: blood very low density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "blood VLDL phospholipid level" RELATED [] is_a: CMO:0001169 ! blood phospholipid level @@ -13623,7 +13623,7 @@ creation_date: 2013-05-08T13:06:06Z [Term] id: CMO:0001572 name: plasma very low density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "plasma VLDL phospholipid level" RELATED [] is_a: CMO:0001170 ! plasma phospholipid level @@ -13634,7 +13634,7 @@ creation_date: 2013-05-08T13:07:22Z [Term] id: CMO:0001573 name: serum very low density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in very low-density lipoprotein (VLDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "serum VLDL phospholipid level" RELATED [] is_a: CMO:0001171 ! serum phospholipid level @@ -13645,7 +13645,7 @@ creation_date: 2013-05-08T13:08:27Z [Term] id: CMO:0001574 name: blood intermediate density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "blood IDL phospholipid level" RELATED [] is_a: CMO:0001169 ! blood phospholipid level @@ -13656,7 +13656,7 @@ creation_date: 2013-05-08T13:10:03Z [Term] id: CMO:0001575 name: plasma intermediate density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "plasma IDL phospholipid level" RELATED [] is_a: CMO:0001170 ! plasma phospholipid level @@ -13667,7 +13667,7 @@ creation_date: 2013-05-08T13:11:19Z [Term] id: CMO:0001576 name: serum intermediate density lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in intermediate-density lipoprotein (IDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. IDL are relatively large lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins. The IDL class of lipoproteins is defined as having a density between 1.006 and 1.019 g/ml." [http://www.thefreedictionary.com/, http://themedicalbiochemistrypage.org/lipoproteins.php] comment: Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided. synonym: "serum IDL phospholipid level" RELATED [] is_a: CMO:0001171 ! serum phospholipid level @@ -13704,7 +13704,7 @@ creation_date: 2013-05-08T14:27:56Z [Term] id: CMO:0001580 name: lymphatic system measurement -def: "Any value resulting from the quantification of a morphological or physiological parameter of the complex network of capillaries, thin vessels, valves, ducts, nodes, and organs that produces various blood cells and helps protect and maintain the internal fluid environment of the entire body by producing, filtering, and conveying lymph, a thin watery fluid that is collected from the organs and tissues, and that serves to remove bacteria and certain proteins from the tissues, transport fat from the small intestine, and supply mature lymphocytes to the blood." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Any value resulting from the quantification of a morphological or physiological parameter of the complex network of capillaries, thin vessels, valves, ducts, nodes, and organs that produces various blood cells and helps protect and maintain the internal fluid environment of the entire body by producing, filtering, and conveying lymph, a thin watery fluid that is collected from the organs and tissues, and that serves to remove bacteria and certain proteins from the tissues, transport fat from the small intestine, and supply mature lymphocytes to the blood." [http://www.thefreedictionary.com/] is_a: CMO:0001579 ! immune system measurement created_by: JSmith creation_date: 2013-05-08T15:08:50Z @@ -13906,7 +13906,7 @@ creation_date: 2013-06-10T13:33:35Z [Term] id: CMO:0001601 name: saccharin intake volume to total fluid intake volume ratio -def: "A calculated measurement of saccharin intake in which the volume, that is, the size of the three dimensional space occupied by a solution of saccharin, a cyclic imine of 2-sulfobenzoic acid which is 500 times sweeter than sugar and used as a nonnutritive sweetener, consumed in a specified period of time is divided by the total volume of all fluids consumed within that period, and presented as a ratio, fraction, quotient or percentage." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated measurement of saccharin intake in which the volume, that is, the size of the three dimensional space occupied by a solution of saccharin, a cyclic imine of 2-sulfobenzoic acid which is 500 times sweeter than sugar and used as a nonnutritive sweetener, consumed in a specified period of time is divided by the total volume of all fluids consumed within that period, and presented as a ratio, fraction, quotient or percentage." [http://www.thefreedictionary.com/] synonym: "intake volume of saccharin to total fluid intake volume ratio" EXACT [] synonym: "ratio of the volume of saccharin consumed to the total volume of fluid consumed" EXACT [] synonym: "saccharin intake volume to total saccharin and water intake volume ratio" RELATED [] @@ -14053,7 +14053,7 @@ creation_date: 2013-06-11T11:47:04Z [Term] id: CMO:0001617 name: percentage of study population developing pituitary tumors that replace the entire gland during a period of time -def: "The number of individuals in a study population which develop new instances of pituitary gland tumors in which the neoplastic tissue completely eliminates and takes the place of all of the normal tissue in the pituitary gland during a specified period of time divided by the total number of individuals in the study population, expressed as a percentage. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The pituitary gland is a small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "The number of individuals in a study population which develop new instances of pituitary gland tumors in which the neoplastic tissue completely eliminates and takes the place of all of the normal tissue in the pituitary gland during a specified period of time divided by the total number of individuals in the study population, expressed as a percentage. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The pituitary gland is a small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [http://www.thefreedictionary.com/] synonym: "incidence of pituitary tumors that replace the entire gland" RELATED [] is_a: CMO:0001029 ! percentage of study population developing pituitary tumors during a period of time created_by: JSmith @@ -14062,7 +14062,7 @@ creation_date: 2013-06-11T18:29:59Z [Term] id: CMO:0001618 name: percentage of study population developing pituitary tumors that replace a portion of the gland during a period of time -def: "The number of individuals in a study population which develop new instances of pituitary gland tumors in which the neoplastic tissue only partially eliminates and takes the place of the normal tissue in the pituitary gland, resulting in a mix of neoplastic and normal tissues, during a specified period of time divided by the total number of individuals in the study population, expressed as a percentage. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The pituitary gland is a small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "The number of individuals in a study population which develop new instances of pituitary gland tumors in which the neoplastic tissue only partially eliminates and takes the place of the normal tissue in the pituitary gland, resulting in a mix of neoplastic and normal tissues, during a specified period of time divided by the total number of individuals in the study population, expressed as a percentage. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The pituitary gland is a small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [http://www.thefreedictionary.com/] synonym: "incidence of pituitary tumors that replace a portion of the gland" RELATED [] is_a: CMO:0001029 ! percentage of study population developing pituitary tumors during a period of time created_by: JSmith @@ -14071,7 +14071,7 @@ creation_date: 2013-06-11T19:20:00Z [Term] id: CMO:0001619 name: percentage of study population developing pituitary tumors that invade the glandular capsule during a period of time -def: "The number of individuals in a study population which develop new instances of pituitary gland tumors in which neoplastic tissue grows into and/or through the membrane surrounding the gland during a specified period of time divided by the total number of individuals in the study population, expressed as a percentage. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The pituitary gland is a small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "The number of individuals in a study population which develop new instances of pituitary gland tumors in which neoplastic tissue grows into and/or through the membrane surrounding the gland during a specified period of time divided by the total number of individuals in the study population, expressed as a percentage. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The pituitary gland is a small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [http://www.thefreedictionary.com/] synonym: "incidence of pituitary tumors that invade the glandular capsule" RELATED [] is_a: CMO:0001029 ! percentage of study population developing pituitary tumors during a period of time created_by: JSmith @@ -14126,7 +14126,7 @@ creation_date: 2013-06-11T20:31:44Z [Term] id: CMO:0001625 name: percentage of disease population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time -def: "The number of new cases of relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) appearing in a study population of individuals that already have experimental autoimmune encephalomyelitis during a certain period compared to the total number of individuals in that already-diseased study population, expressed as a percentage. R-EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of new cases of relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) appearing in a study population of individuals that already have experimental autoimmune encephalomyelitis during a certain period compared to the total number of individuals in that already-diseased study population, expressed as a percentage. R-EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "incidence of relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) in a disease population" RELATED [] is_a: CMO:0001402 ! percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time created_by: JSmith @@ -14135,7 +14135,7 @@ creation_date: 2013-06-12T11:25:57Z [Term] id: CMO:0001626 name: percentage of disease population displaying relapsing-remitting experimental autoimmune encephalomyelitis at a point in time -def: "The number of individuals in a study population of individuals that already have experimental autoimmune encephalomyelitis which display relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) at a certain point in time compared to the total number of individuals in that already-diseased study population, expressed as a percentage. R-EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of individuals in a study population of individuals that already have experimental autoimmune encephalomyelitis which display relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) at a certain point in time compared to the total number of individuals in that already-diseased study population, expressed as a percentage. R-EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells where such induction results in a disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "prevalence of relapsing-remitting experimental autoimmune encephalomyelitis (R-EAE) in a disease population" RELATED [] is_a: CMO:0001403 ! percentage of study population displaying relapsing-remitting experimental autoimmune encephalomyelitis at a point in time created_by: JSmith @@ -14144,7 +14144,7 @@ creation_date: 2013-06-12T11:28:11Z [Term] id: CMO:0001627 name: saline drink intake rate -def: "The amount of a solution of sodium chloride that is consumed as a drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., per unit time. A sodium chloride solution is homogeneous mixture of atoms of sodium, the chemical element with atomic number 11, that have lost one electron forming a cation with a charge of +1, and an equivalent number of atoms of chlorine, the chemical element with atomic number 17, that have gained one electron forming an anion with a charge of -1 dispersed molecularly in a sufficient quantity of dissolving medium (solvent) such as water." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, YourDictionary:http\://www.yourdictionary.com/drink] +def: "The amount of a solution of sodium chloride that is consumed as a drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., per unit time. A sodium chloride solution is homogeneous mixture of atoms of sodium, the chemical element with atomic number 11, that have lost one electron forming a cation with a charge of +1, and an equivalent number of atoms of chlorine, the chemical element with atomic number 17, that have gained one electron forming an anion with a charge of -1 dispersed molecularly in a sufficient quantity of dissolving medium (solvent) such as water." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.yourdictionary.com/drink] synonym: "isotonic saline intake rate" RELATED [] synonym: "normal saline intake rate" RELATED [] synonym: "physiological saline intake rate" RELATED [] @@ -14156,7 +14156,7 @@ creation_date: 2013-06-12T11:51:49Z [Term] id: CMO:0001628 name: saline drink intake volume -def: "The amount of a solution of sodium chloride that is consumed as a drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., during a specified period of time. A sodium chloride solution is homogeneous mixture of atoms of sodium, the chemical element with atomic number 11, that have lost one electron forming a cation with a charge of +1, and an equivalent number of atoms of chlorine, the chemical element with atomic number 17, that have gained one electron forming an anion with a charge of -1 dispersed molecularly in a sufficient quantity of dissolving medium (solvent) such as water." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, YourDictionary:http\://www.yourdictionary.com/drink] +def: "The amount of a solution of sodium chloride that is consumed as a drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., during a specified period of time. A sodium chloride solution is homogeneous mixture of atoms of sodium, the chemical element with atomic number 11, that have lost one electron forming a cation with a charge of +1, and an equivalent number of atoms of chlorine, the chemical element with atomic number 17, that have gained one electron forming an anion with a charge of -1 dispersed molecularly in a sufficient quantity of dissolving medium (solvent) such as water." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.yourdictionary.com/drink] synonym: "isotonic saline intake volume" RELATED [] synonym: "normal saline intake volume" RELATED [] synonym: "physiological saline intake volume" RELATED [] @@ -14213,7 +14213,7 @@ creation_date: 2013-06-14T16:18:30Z [Term] id: CMO:0001634 name: absolute change in urine norepinephrine level -def: "The difference in the amount of norepinephrine, a catecholamine hormone and neurotransmitter, secreted by the adrenal medulla and the nerve endings of the sympathetic nervous system, that causes vasoconstriction and increases heart rate, blood pressure, and blood sugar level, in a specified sample of urine, the fluid waste product excreted by the kidneys, between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F)] +def: "The difference in the amount of norepinephrine, a catecholamine hormone and neurotransmitter, secreted by the adrenal medulla and the nerve endings of the sympathetic nervous system, that causes vasoconstriction and increases heart rate, blood pressure, and blood sugar level, in a specified sample of urine, the fluid waste product excreted by the kidneys, between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F)] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in urine noradrenalin level" EXACT [] is_a: CMO:0001633 ! calculated urine norepinephrine level @@ -14233,7 +14233,7 @@ creation_date: 2013-06-14T16:21:02Z [Term] id: CMO:0001636 name: absolute change in urine vanillylmandelic acid level -def: "The difference in the amount of vanillylmandelic acid, the major urinary metabolite of adrenal and sympathetic catecholamines such as epinephrine and norepinephrine, in a specified sample of urine, the fluid waste product excreted by the kidneys, between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F)] +def: "The difference in the amount of vanillylmandelic acid, the major urinary metabolite of adrenal and sympathetic catecholamines such as epinephrine and norepinephrine, in a specified sample of urine, the fluid waste product excreted by the kidneys, between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [http://www.thefreedictionary.com/, http://www.psychwiki.com/wiki/What_is_absolute_change%3F)] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in urine 3-methoxy-4-hydroxymandelic acid level" EXACT [] synonym: "absolute change in urine VMA level" RELATED [] @@ -14252,7 +14252,7 @@ creation_date: 2013-06-17T17:52:42Z [Term] id: CMO:0001638 name: single inguinal fat pad weight to body weight ratio -def: "A calculated value in which the weight of one of the inguinal fat pads, that is, the accumulations of encapsulated adipose tissue located in the junctional region between the abdomen and thigh, is divided by the total weight of the body and presented as a ratio, fraction or quotient, thus normalizing it to body weight and, by extension, to the size of the organism." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated value in which the weight of one of the inguinal fat pads, that is, the accumulations of encapsulated adipose tissue located in the junctional region between the abdomen and thigh, is divided by the total weight of the body and presented as a ratio, fraction or quotient, thus normalizing it to body weight and, by extension, to the size of the organism." [http://www.thefreedictionary.com/] is_a: CMO:0001253 ! inguinal fat pad weight to body weight ratio created_by: JSmith creation_date: 2013-06-17T18:06:36Z @@ -14260,7 +14260,7 @@ creation_date: 2013-06-17T18:06:36Z [Term] id: CMO:0001639 name: both inguinal fat pads weight to body weight ratio -def: "A calculated value in which the total weight of both of the inguinal fat pads, that is, the accumulations of encapsulated adipose tissue located in the junctional region between the abdomen and thigh, is divided by the total weight of the body and presented as a ratio, fraction or quotient, thus normalizing it to body weight and, by extension, to the size of the organism." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated value in which the total weight of both of the inguinal fat pads, that is, the accumulations of encapsulated adipose tissue located in the junctional region between the abdomen and thigh, is divided by the total weight of the body and presented as a ratio, fraction or quotient, thus normalizing it to body weight and, by extension, to the size of the organism." [http://www.thefreedictionary.com/] is_a: CMO:0001253 ! inguinal fat pad weight to body weight ratio created_by: JSmith creation_date: 2013-06-17T18:09:01Z @@ -14268,7 +14268,7 @@ creation_date: 2013-06-17T18:09:01Z [Term] id: CMO:0001640 name: blood vessel smooth muscle measurement -def: "A value resulting from the quantification of a morphological or physiological parameter of vascular smooth muscle, the contractile soft tissue having fine myofibrils but lacking transverse striations composing the majority of the wall of blood vessels, the network of muscular tubes that carry blood through the body." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Vascular_smooth_muscle] +def: "A value resulting from the quantification of a morphological or physiological parameter of vascular smooth muscle, the contractile soft tissue having fine myofibrils but lacking transverse striations composing the majority of the wall of blood vessels, the network of muscular tubes that carry blood through the body." [http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Vascular_smooth_muscle] synonym: "Not4Curation" RELATED [] synonym: "vascular smooth muscle measurement" EXACT [] is_a: CMO:0000077 ! blood vessel measurement @@ -14333,7 +14333,7 @@ creation_date: 2013-06-18T13:25:39Z [Term] id: CMO:0001647 name: heart left ventricle deoxyribonucleic acid content -def: "The amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart left ventricle, the lower chamber of the left side of the heart (from the perspective of the organism rather than the observer), which pumps oxygenated blood out through the aorta to all the tissues of the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location] +def: "The amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart left ventricle, the lower chamber of the left side of the heart (from the perspective of the organism rather than the observer), which pumps oxygenated blood out through the aorta to all the tissues of the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "heart left ventricle DNA content" RELATED [] synonym: "heart LV DNA content" RELATED [] is_a: CMO:0002164 ! heart left ventricle molecular composition measurement @@ -14344,7 +14344,7 @@ creation_date: 2013-06-18T14:44:11Z [Term] id: CMO:0001648 name: calculated heart left ventricle deoxyribonucleic acid content -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart left ventricle, the lower chamber of the left side of the heart (from the perspective of the organism rather than the observer), which pumps oxygenated blood out through the aorta to all the tissues of the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart left ventricle, the lower chamber of the left side of the heart (from the perspective of the organism rather than the observer), which pumps oxygenated blood out through the aorta to all the tissues of the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "calculated heart left ventricle DNA content" RELATED [] synonym: "calculated heart LV DNA content" RELATED [] is_a: CMO:0000984 ! calculated heart left ventricle morphological measurement @@ -14355,7 +14355,7 @@ creation_date: 2013-06-18T14:46:40Z [Term] id: CMO:0001649 name: heart left ventricle deoxyribonucleic acid content to body weight ratio -def: "A calculated measurement in which amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart left ventricle, the lower chamber of the left side of the heart (from the perspective of the organism rather than the observer), which pumps oxygenated blood out through the aorta to all the tissues of the body, is divided by the total weight or heaviness of the body and presented as a ratio, fraction, quotient or percentage, thus normalizing it to body weight and, by extension, to the size of the organism." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location] +def: "A calculated measurement in which amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart left ventricle, the lower chamber of the left side of the heart (from the perspective of the organism rather than the observer), which pumps oxygenated blood out through the aorta to all the tissues of the body, is divided by the total weight or heaviness of the body and presented as a ratio, fraction, quotient or percentage, thus normalizing it to body weight and, by extension, to the size of the organism." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "heart left ventricle DNA content to body weight ratio" RELATED [] synonym: "heart left ventricle DNA content to BW ratio" RELATED [] synonym: "heart LV DNA content to body weight ratio" RELATED [] @@ -14366,7 +14366,7 @@ creation_date: 2013-06-18T14:49:33Z [Term] id: CMO:0001650 name: heart right ventricle deoxyribonucleic acid content -def: "The amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart right ventricle, the lower chamber of the right side of the heart (from the perspective of the organism rather than the observer), which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location] +def: "The amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart right ventricle, the lower chamber of the right side of the heart (from the perspective of the organism rather than the observer), which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "heart right ventricle DNA content" RELATED [] synonym: "heart RV DNA content" RELATED [] is_a: CMO:0000952 ! heart right ventricle morphological measurement @@ -14376,7 +14376,7 @@ creation_date: 2013-06-18T14:52:32Z [Term] id: CMO:0001651 name: calculated heart right ventricle deoxyribonucleic acid content -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart right ventricle, the lower chamber of the right side of the heart (from the perspective of the organism rather than the observer), which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart right ventricle, the lower chamber of the right side of the heart (from the perspective of the organism rather than the observer), which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "calculated heart right ventricle DNA content" RELATED [] synonym: "calculated heart RV DNA content" RELATED [] is_a: CMO:0001125 ! calculated heart right ventricle morphological measurement @@ -14387,7 +14387,7 @@ creation_date: 2013-06-18T14:54:27Z [Term] id: CMO:0001652 name: heart right ventricle deoxyribonucleic acid content to body weight ratio -def: "A calculated measurement in which amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart right ventricle, the lower chamber of the right side of the heart (from the perspective of the organism rather than the observer), which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung, is divided by the total weight or heaviness of the body and presented as a ratio, fraction, quotient or percentage, thus normalizing it to body weight and, by extension, to the size of the organism." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location] +def: "A calculated measurement in which amount of deoxyribonucleic acid (DNA), the molecule composed of the sugar deoxyribose, phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, extracted from or contained in the heart right ventricle, the lower chamber of the right side of the heart (from the perspective of the organism rather than the observer), which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung, is divided by the total weight or heaviness of the body and presented as a ratio, fraction, quotient or percentage, thus normalizing it to body weight and, by extension, to the size of the organism." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "heart right ventricle DNA content to body weight ratio" RELATED [] synonym: "heart right ventricle DNA content to BW ratio" RELATED [] synonym: "heart RV DNA content to body weight ratio" RELATED [] @@ -14398,7 +14398,7 @@ creation_date: 2013-06-18T14:56:34Z [Term] id: CMO:0001653 name: receptor-independent blood vessel maximum contractile force -def: "Measurement of the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from a contraction of the muscular wall of the vessel which does not involve the action of a receptor, a molecule on the surface or within a cell that recognizes and binds with specific molecules, producing a specific effect." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Vasoconstriction] +def: "Measurement of the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from a contraction of the muscular wall of the vessel which does not involve the action of a receptor, a molecule on the surface or within a cell that recognizes and binds with specific molecules, producing a specific effect." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Vasoconstriction] synonym: "blood vessel receptor-independent maximum contractility" RELATED [] is_a: CMO:0000717 ! blood vessel maximum contractile force created_by: JSmith @@ -14407,7 +14407,7 @@ creation_date: 2013-06-20T14:09:54Z [Term] id: CMO:0001654 name: receptor-dependent blood vessel maximum contractile force -def: "Measurement of the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from a contraction of the muscular wall of the vessel which is instigated by the activation of a receptor, a molecule on the surface or within a cell that recognizes and binds with specific molecules, producing a specific effect." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Vasoconstriction] +def: "Measurement of the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from a contraction of the muscular wall of the vessel which is instigated by the activation of a receptor, a molecule on the surface or within a cell that recognizes and binds with specific molecules, producing a specific effect." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Vasoconstriction] synonym: "blood vessel receptor-dependent maximum contractility" RELATED [] is_a: CMO:0000717 ! blood vessel maximum contractile force created_by: JSmith @@ -14416,7 +14416,7 @@ creation_date: 2013-06-20T14:10:59Z [Term] id: CMO:0001655 name: calculated blood vessel maximum contractile force measurement -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from contraction of the muscular wall of the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Vasoconstriction] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from contraction of the muscular wall of the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Vasoconstriction] is_a: CMO:0000717 ! blood vessel maximum contractile force is_a: CMO:0000720 ! calculated blood vessel contractile force measurement created_by: JSmith @@ -14425,7 +14425,7 @@ creation_date: 2013-06-20T14:12:17Z [Term] id: CMO:0001656 name: receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio -def: "A calculated measurement in which the receptor-dependent maximum contractile force of a blood vessel is divided by the receptor-independent maximum contractile force of a blood vessel and presented as a ratio, fraction, quotient or percentage. The maximum contractile force of a blood vessel is the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from a contraction of the muscular wall of the vessel. Receptor-dependent refers to such a contraction which is instigated by the activation of a receptor, a molecule on the surface or within a cell that recognizes and binds with specific molecules, producing a specific effect. Receptor-independent denotes such a contraction that does not involve the action of a receptor." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Vasoconstriction] +def: "A calculated measurement in which the receptor-dependent maximum contractile force of a blood vessel is divided by the receptor-independent maximum contractile force of a blood vessel and presented as a ratio, fraction, quotient or percentage. The maximum contractile force of a blood vessel is the highest achievable amount of energy produced by the active reduction in the diameter of a blood vessel, any one of the network of muscular tubes that carry blood through the body, resulting from a contraction of the muscular wall of the vessel. Receptor-dependent refers to such a contraction which is instigated by the activation of a receptor, a molecule on the surface or within a cell that recognizes and binds with specific molecules, producing a specific effect. Receptor-independent denotes such a contraction that does not involve the action of a receptor." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Vasoconstriction] synonym: "blood vessel receptor-dependent contractility to receptor-independent contractility ratio" RELATED [] synonym: "receptor-dependent blood vessel maximum contractile force exoressed as a percentage of receptor-independent blood vessel maximum contractile force" RELATED [] is_a: CMO:0001655 ! calculated blood vessel maximum contractile force measurement @@ -14435,7 +14435,7 @@ creation_date: 2013-06-20T14:14:00Z [Term] id: CMO:0001657 name: concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (EC50) -def: "A calculated value for the concentration of angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of AngII is halfway between the baseline value and the highest achievable value of such AngII-induced contractile energy." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for the concentration of angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of AngII is halfway between the baseline value and the highest achievable value of such AngII-induced contractile energy." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II, https://en.wikipedia.org/wiki/EC50] synonym: "Ang2 half maximal effective concentration" RELATED [] synonym: "AngII half maximal effective concentration" RELATED [] synonym: "angiotensin 2 half maximal effective concentration" RELATED [] @@ -14449,7 +14449,7 @@ creation_date: 2013-06-20T14:22:08Z [Term] id: CMO:0001658 name: logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50) -def: "A calculated value for logarithm of the concentration of angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of AngII is halfway between the baseline value and the highest achievable value of such AngII-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for logarithm of the concentration of angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of AngII is halfway between the baseline value and the highest achievable value of such AngII-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II, https://en.wikipedia.org/wiki/EC50] synonym: "Ang2 Log half maximal effective concentration" RELATED [] synonym: "AngII Log half maximal effective concentration" RELATED [] synonym: "angiotensin 2 Log half maximal effective concentration" RELATED [] @@ -14463,7 +14463,7 @@ creation_date: 2013-06-20T14:24:41Z [Term] id: CMO:0001659 name: angiotensin II response/sensitivity measurement -def: "Measurement of an organism's, organ's, tissue's or cell's capacity to respond, such as by a change in activity, state or condition, to angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II] +def: "Measurement of an organism's, organ's, tissue's or cell's capacity to respond, such as by a change in activity, state or condition, to angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Angiotensin#Angiotensin_II] xref: CHEBI:48432 is_a: CMO:0000719 ! chemical response/sensitivity measurement created_by: JSmith @@ -14546,7 +14546,7 @@ creation_date: 2013-06-27T16:17:13Z [Term] id: CMO:0001668 name: femur polar moment of inertia -def: "A calculated geometric property of a cross section of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, Website:http\://www.ah-engr.com/som/animations/polar_moment.html] +def: "A calculated geometric property of a cross section of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, http://www.ah-engr.com/som/animations/polar_moment.html] synonym: "femoral polar moment of inertia" EXACT [] synonym: "femur area moment of inertia" RELATED [] synonym: "femur cross-sectional moment of inertia" RELATED [] @@ -14559,7 +14559,7 @@ creation_date: 2013-06-27T18:05:54Z [Term] id: CMO:0001669 name: femur midshaft polar moment of inertia -def: "A calculated geometric property of a cross section of the femoral midshaft, a point midway between the two ends of the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, Website:http\://www.ah-engr.com/som/animations/polar_moment.html] +def: "A calculated geometric property of a cross section of the femoral midshaft, a point midway between the two ends of the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, http://www.ah-engr.com/som/animations/polar_moment.html] synonym: "femoral midshaft polar moment of inertia" EXACT [] synonym: "femur midshaft area moment of inertia" RELATED [] synonym: "femur midshaft cross-sectional moment of inertia" RELATED [] @@ -14572,7 +14572,7 @@ creation_date: 2013-06-27T18:08:04Z [Term] id: CMO:0001670 name: femoral neck polar moment of inertia -def: "A calculated geometric property of a cross section of the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, Website:http\://www.ah-engr.com/som/animations/polar_moment.html, Wikipedia:http\://en.wikipedia.org/wiki/Femur_neck] +def: "A calculated geometric property of a cross section of the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. It is a measure of the distribution of material around a given axis and is related to the inherent rotational stiffness of the bone around that axis. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8274302, http://www.ah-engr.com/som/animations/polar_moment.html, https://en.wikipedia.org/wiki/Femur_neck] synonym: "femoral neck area moment of inertia" RELATED [] synonym: "femoral neck cross-sectional moment of inertia" RELATED [] synonym: "femoral neck Ip" RELATED [] @@ -14593,7 +14593,7 @@ creation_date: 2013-06-27T18:23:18Z [Term] id: CMO:0001672 name: femoral neck morphological measurement -def: "Measurement of the physical form or structure of the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Femur_neck] +def: "Measurement of the physical form or structure of the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, https://en.wikipedia.org/wiki/Femur_neck] synonym: "femur neck morphological measurement" EXACT [] is_a: CMO:0001377 ! femur morphological measurement created_by: JSmith @@ -14602,7 +14602,7 @@ creation_date: 2013-06-27T18:24:52Z [Term] id: CMO:0001673 name: bone stiffness -def: "A calculated measurement of the rigidity of a bone, that is, the extent to which it resists deformation in response to an applied force, taken as the initial, i.e. the maximum, slope of the load-displacement curve. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:16059631, Wikipedia:http\://en.wikipedia.org/wiki/Stiffness] +def: "A calculated measurement of the rigidity of a bone, that is, the extent to which it resists deformation in response to an applied force, taken as the initial, i.e. the maximum, slope of the load-displacement curve. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:16059631, https://en.wikipedia.org/wiki/Stiffness] is_a: CMO:0001557 ! bone biomechanical measurement created_by: JSmith creation_date: 2013-06-27T18:35:15Z @@ -14610,7 +14610,7 @@ creation_date: 2013-06-27T18:35:15Z [Term] id: CMO:0001674 name: femur stiffness -def: "A calculated measurement of the rigidity of the femur, that is, the extent to which it resists deformation in response to an applied force, taken as the initial, i.e. the maximum, slope of the load-displacement curve. The femur is the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:16059631, Wikipedia:http\://en.wikipedia.org/wiki/Stiffness] +def: "A calculated measurement of the rigidity of the femur, that is, the extent to which it resists deformation in response to an applied force, taken as the initial, i.e. the maximum, slope of the load-displacement curve. The femur is the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:16059631, https://en.wikipedia.org/wiki/Stiffness] synonym: "femoral stiffness" EXACT [] xref: MA:0001359 is_a: CMO:0001664 ! femur biomechanical measurement @@ -14727,7 +14727,7 @@ creation_date: 2013-07-08T17:55:14Z [Term] id: CMO:0001685 name: vertebra cross-sectional area -def: "A measurement of the extent of a plane through, that is, perpendicular to the axis of, a vertebra, any of the individual bones forming the spinal column, the protective bony corridor through which the spinal cord passes." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the extent of a plane through, that is, perpendicular to the axis of, a vertebra, any of the individual bones forming the spinal column, the protective bony corridor through which the spinal cord passes." [http://www.thefreedictionary.com/] synonym: "vertebral cross-sectional area" EXACT [] synonym: "vertebra total cross-sectional area" RELATED [] is_a: CMO:0001684 ! vertebra area @@ -14738,7 +14738,7 @@ creation_date: 2013-07-08T18:10:28Z [Term] id: CMO:0001686 name: vertebra cortical cross-sectional area -def: "The portion of the cross-sectional area of a vertebra that corresponds to the area of the cortex, the outer, more dense layer of the bone. The cross-sectional area of a vertebra is a measurement of the extent of a plane through, i.e. perpendicular to the axis of, a vertebra, any of the individual bones forming the spinal column, the protective bony corridor through which the spinal cord passes." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "The portion of the cross-sectional area of a vertebra that corresponds to the area of the cortex, the outer, more dense layer of the bone. The cross-sectional area of a vertebra is a measurement of the extent of a plane through, i.e. perpendicular to the axis of, a vertebra, any of the individual bones forming the spinal column, the protective bony corridor through which the spinal cord passes." [http://www.thefreedictionary.com/] synonym: "vertebra compact bone cross-sectional area" RELATED [] synonym: "vertebra cortex cross-sectional area" RELATED [] synonym: "vertebra cortical bone cross-sectional area" EXACT [] @@ -14750,7 +14750,7 @@ creation_date: 2013-07-08T18:12:28Z [Term] id: CMO:0001687 name: lumbar vertebra morphological measurement -def: "A value resulting from the quantification of the physical form or structure of one or more lumbar vertebrae, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A value resulting from the quantification of the physical form or structure of one or more lumbar vertebrae, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region." [http://www.thefreedictionary.com/] synonym: "lumbar vertebrae morphological measurement" RELATED [] is_a: CMO:0001679 ! vertebra morphological measurement created_by: JSmith @@ -14759,7 +14759,7 @@ creation_date: 2013-07-08T18:17:12Z [Term] id: CMO:0001688 name: lumbar vertebra area -def: "A measurement of the extent of a two-dimensional surface of or plane through a lumbar vertebra, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the extent of a two-dimensional surface of or plane through a lumbar vertebra, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region." [http://www.thefreedictionary.com/] is_a: CMO:0001684 ! vertebra area is_a: CMO:0001687 ! lumbar vertebra morphological measurement created_by: JSmith @@ -14768,7 +14768,7 @@ creation_date: 2013-07-08T18:19:48Z [Term] id: CMO:0001689 name: lumbar vertebra cross-sectional area -def: "A measurement of the extent of a plane through, that is, perpendicular to the axis of, a lumbar vertebra, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region. The area includes any or all of the bone elements present at the level of the cross-sectional plane, including cortical bone, trabecular bone and/or marrow." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the extent of a plane through, that is, perpendicular to the axis of, a lumbar vertebra, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region. The area includes any or all of the bone elements present at the level of the cross-sectional plane, including cortical bone, trabecular bone and/or marrow." [http://www.thefreedictionary.com/] synonym: "lumbar vertebral cross-sectional area" EXACT [] synonym: "lumbar vertebra total cross-sectional area" RELATED [] is_a: CMO:0001685 ! vertebra cross-sectional area @@ -14779,7 +14779,7 @@ creation_date: 2013-07-08T18:31:57Z [Term] id: CMO:0001690 name: lumbar vertebra cortical cross-sectional area -def: "The portion of the cross-sectional area of a lumbar vertebra that corresponds to the area of the cortex, the outer layer of the bone. The cross-sectional area of a lumbar vertebra is a measurement of the extent of a plane through, i.e. perpendicular to the axis of, a lumbar vertebra, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "The portion of the cross-sectional area of a lumbar vertebra that corresponds to the area of the cortex, the outer layer of the bone. The cross-sectional area of a lumbar vertebra is a measurement of the extent of a plane through, i.e. perpendicular to the axis of, a lumbar vertebra, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region." [http://www.thefreedictionary.com/] synonym: "lumbar vertebra compact bone cross-sectional area" EXACT [] synonym: "lumbar vertebral cortical cross-sectional area" EXACT [] is_a: CMO:0001686 ! vertebra cortical cross-sectional area @@ -14790,7 +14790,7 @@ creation_date: 2013-07-08T18:32:58Z [Term] id: CMO:0001691 name: vertebra trabecular cross-sectional area -def: "The portion of the cross-sectional area of a vertebra that corresponds to the area occupied by cancellous or spongy bone, the inner, less dense, more metabolically active type of osseous tissue made up of a network of tiny lattice-shaped spicules often containing marrow. The cross-sectional area of a vertebra is a measurement of the extent of a plane through, i.e. perpendicular to the axis of, a vertebra, any of the individual bones forming the spinal column, the protective bony corridor through which the spinal cord passes." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Trabecular_bone] +def: "The portion of the cross-sectional area of a vertebra that corresponds to the area occupied by cancellous or spongy bone, the inner, less dense, more metabolically active type of osseous tissue made up of a network of tiny lattice-shaped spicules often containing marrow. The cross-sectional area of a vertebra is a measurement of the extent of a plane through, i.e. perpendicular to the axis of, a vertebra, any of the individual bones forming the spinal column, the protective bony corridor through which the spinal cord passes." [http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Trabecular_bone] synonym: "vertebra cancellous bone cross-sectional area" RELATED [] synonym: "vertebral trabecular cross-sectional area" EXACT [] synonym: "vertebra spongy bone cross-sectional area" RELATED [] @@ -14804,7 +14804,7 @@ creation_date: 2013-07-09T16:32:54Z [Term] id: CMO:0001692 name: lumbar vertebra trabecular cross-sectional area -def: "The portion of the cross-sectional area of a lumbar vertebra that corresponds to the area occupied by cancellous or spongy bone, the inner, less dense, more metabolically active type of osseous tissue made up of a network of tiny lattice-shaped spicules often containing marrow. The cross-sectional area of a lumbar vertebra is a measurement of the extent of a plane through, i.e. perpendicular to the axis of, a lumbar vertebra, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Trabecular_bone] +def: "The portion of the cross-sectional area of a lumbar vertebra that corresponds to the area occupied by cancellous or spongy bone, the inner, less dense, more metabolically active type of osseous tissue made up of a network of tiny lattice-shaped spicules often containing marrow. The cross-sectional area of a lumbar vertebra is a measurement of the extent of a plane through, i.e. perpendicular to the axis of, a lumbar vertebra, any of the individual bones forming the portion of the spinal column (the protective bony corridor through which the spinal cord passes) between the thoracic vertebrae in the chest region and the sacrum in the hip region." [http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Trabecular_bone] synonym: "lumbar vertebra cancellous bone cross-sectional area" RELATED [] synonym: "lumbar vertebral trabecular cross-sectional area" EXACT [] synonym: "lumbar vertebra spongy bone cross-sectional area" RELATED [] @@ -14827,7 +14827,7 @@ creation_date: 2013-07-09T17:41:58Z [Term] id: CMO:0001694 name: calculated femur cross-sectional area -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the extent of a plane through, that is, perpendicular to the longest axis of, the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the extent of a plane through, that is, perpendicular to the longest axis of, the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [http://www.thefreedictionary.com/] is_a: CMO:0001661 ! femur cross-sectional area is_a: CMO:0001682 ! calculated bone cross-sectional area measurement created_by: JSmith @@ -14836,7 +14836,7 @@ creation_date: 2013-07-09T17:45:58Z [Term] id: CMO:0001695 name: femoral neck width -def: "The shortest transverse distance across the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, PMID:18282130, Wikipedia:http\://en.wikipedia.org/wiki/Femur_neck] +def: "The shortest transverse distance across the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, PMID:18282130, https://en.wikipedia.org/wiki/Femur_neck] synonym: "femur neck width" EXACT [] is_a: CMO:0001672 ! femoral neck morphological measurement created_by: JSmith @@ -14845,7 +14845,7 @@ creation_date: 2013-07-10T11:54:53Z [Term] id: CMO:0001696 name: femoral neck area -def: "A measurement of the extent of a two-dimensional surface of or plane through the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Femur_neck] +def: "A measurement of the extent of a two-dimensional surface of or plane through the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Femur_neck] is_a: CMO:0001672 ! femoral neck morphological measurement created_by: JSmith creation_date: 2013-07-10T12:49:54Z @@ -14853,7 +14853,7 @@ creation_date: 2013-07-10T12:49:54Z [Term] id: CMO:0001697 name: femoral neck cross-sectional area -def: "A measurement of the extent of a plane through, that is, perpendicular to the longest axis of, the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Femur_neck] +def: "A measurement of the extent of a plane through, that is, perpendicular to the longest axis of, the femoral neck, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Femur_neck] synonym: "total femoral neck cross-sectional area" RELATED [] is_a: CMO:0001661 ! femur cross-sectional area is_a: CMO:0001696 ! femoral neck area @@ -14863,7 +14863,7 @@ creation_date: 2013-07-10T12:51:05Z [Term] id: CMO:0001698 name: calculated femoral neck cross-sectional area -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the extent of a plane through, that is, perpendicular to the longest axis of, the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Femur_neck] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the extent of a plane through, that is, perpendicular to the longest axis of, the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Femur_neck] is_a: CMO:0001694 ! calculated femur cross-sectional area is_a: CMO:0001697 ! femoral neck cross-sectional area created_by: JSmith @@ -14880,7 +14880,7 @@ creation_date: 2013-07-10T12:55:24Z [Term] id: CMO:0001700 name: femur midshaft cross-sectional area -def: "A measurement of the extent of a plane through the femoral midshaft, a point midway between the two ends of the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. The plane of the cross-section would be perpendicular to the longest axis of the femur." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the extent of a plane through the femoral midshaft, a point midway between the two ends of the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. The plane of the cross-section would be perpendicular to the longest axis of the femur." [http://www.thefreedictionary.com/] is_a: CMO:0001699 ! femur midshaft area created_by: JSmith creation_date: 2013-07-10T12:56:21Z @@ -14888,7 +14888,7 @@ creation_date: 2013-07-10T12:56:21Z [Term] id: CMO:0001701 name: calculated femur midshaft cross-sectional area -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the extent of a plane through the femoral midshaft, a point midway between the two ends of the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. The plane of the cross-section would be perpendicular to the longest axis of the femur." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the extent of a plane through the femoral midshaft, a point midway between the two ends of the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds. The plane of the cross-section would be perpendicular to the longest axis of the femur." [http://www.thefreedictionary.com/] is_a: CMO:0001694 ! calculated femur cross-sectional area is_a: CMO:0001700 ! femur midshaft cross-sectional area created_by: JSmith @@ -14897,7 +14897,7 @@ creation_date: 2013-07-10T12:57:07Z [Term] id: CMO:0001702 name: femoral neck cortical cross-sectional area -def: "The portion of the cross-sectional area of the femoral neck that corresponds to the area of the cortex, the outer, more dense layer of the bone. The cross-sectional area of the femoral neck is a measurement of the extent of a plane through, that is, perpendicular to the longest axis of, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Femur_neck] +def: "The portion of the cross-sectional area of the femoral neck that corresponds to the area of the cortex, the outer, more dense layer of the bone. The cross-sectional area of the femoral neck is a measurement of the extent of a plane through, that is, perpendicular to the longest axis of, the heavy, flattened, pyramidal process of bone connecting the head and the shaft of the femur, the major bone in the upper portion of the hindlimb of quadrupeds or the lower limb of bipeds." [http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Femur_neck] synonym: "femoral neck cortex cross-sectional area" RELATED [] is_a: CMO:0001697 ! femoral neck cross-sectional area created_by: JSmith @@ -14945,7 +14945,7 @@ creation_date: 2013-07-26T13:39:11Z [Term] id: CMO:0001707 name: benign liver tumor number -def: "A value or quantity determined by count of abnormal but benign growths of tissue in the liver or in a specified sample of liver tissue, i.e. growths that result from uncontrolled, progressive multiplication of cells which serve no physiological function, but that are generally stable, treatable, circumscribed, that is, not displaying invasiveness or metastasis, and in a relatively normal state of differentiation. The liver is the large, dark-red organ located in the cranial portion of the abdomen of vertebrates, just behind or below the diaphragm, the functions of which include storage and filtration of blood; secretion of bile; detoxification of noxious substances; conversion of sugars into glycogen; synthesis and breakdown of fats and temporary storage of fatty acids; and synthesis of serum proteins." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A value or quantity determined by count of abnormal but benign growths of tissue in the liver or in a specified sample of liver tissue, i.e. growths that result from uncontrolled, progressive multiplication of cells which serve no physiological function, but that are generally stable, treatable, circumscribed, that is, not displaying invasiveness or metastasis, and in a relatively normal state of differentiation. The liver is the large, dark-red organ located in the cranial portion of the abdomen of vertebrates, just behind or below the diaphragm, the functions of which include storage and filtration of blood; secretion of bile; detoxification of noxious substances; conversion of sugars into glycogen; synthesis and breakdown of fats and temporary storage of fatty acids; and synthesis of serum proteins." [http://www.thefreedictionary.com/] synonym: "benign hepatic tumor number" EXACT [] synonym: "benign liver tumor count" EXACT [] is_a: CMO:0001706 ! liver tumor number @@ -14955,7 +14955,7 @@ creation_date: 2013-07-26T15:30:00Z [Term] id: CMO:0001708 name: malignant liver tumor number -def: "A value or quantity determined by count of abnormal, malignant growths of tissue in the liver or in a specified sample of liver tissue, i.e. growths that result from uncontrolled, progressive multiplication of cells, that serve no physiological function, and that display the properties of anaplasia, invasiveness and metastasis. The liver is the large, dark-red organ located in the cranial portion of the abdomen of vertebrates, just behind or below the diaphragm, the functions of which include storage and filtration of blood; secretion of bile; detoxification of noxious substances; conversion of sugars into glycogen; synthesis and breakdown of fats and temporary storage of fatty acids; and synthesis of serum proteins." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A value or quantity determined by count of abnormal, malignant growths of tissue in the liver or in a specified sample of liver tissue, i.e. growths that result from uncontrolled, progressive multiplication of cells, that serve no physiological function, and that display the properties of anaplasia, invasiveness and metastasis. The liver is the large, dark-red organ located in the cranial portion of the abdomen of vertebrates, just behind or below the diaphragm, the functions of which include storage and filtration of blood; secretion of bile; detoxification of noxious substances; conversion of sugars into glycogen; synthesis and breakdown of fats and temporary storage of fatty acids; and synthesis of serum proteins." [http://www.thefreedictionary.com/] synonym: "malignant hepatic tumor number" EXACT [] synonym: "malignant liver tumor count" EXACT [] is_a: CMO:0001706 ! liver tumor number @@ -15094,7 +15094,7 @@ creation_date: 2013-07-29T11:30:31Z [Term] id: CMO:0001721 name: tibia-fibula cortical bone total cross-sectional area -def: "Measurement of the entire cross-sectional area of the tibia-fibula cortical bone, that is, the extent of a plane perpendicular to the longest axis of the tibia-fibula cortical bone and bounded by the periosteum, the thick fibrous membrane covering the entire surface of a bone except its articular cartilage and serving as an attachment for muscles and tendons. The tibia-fibula is the portion of the two bones (tibia, the medial and larger bone, and fibula, the lateral and smaller bone) of the lower leg of bipeds or hindlimb of quadrupeds which are fused to form a single bone, e.g. the distal third of the rodent tibia and fibula. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a ollagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, PMID:20699128, PMID:857566, Website:http\://biomech2.me.berkeley.edu/cortical.html] +def: "Measurement of the entire cross-sectional area of the tibia-fibula cortical bone, that is, the extent of a plane perpendicular to the longest axis of the tibia-fibula cortical bone and bounded by the periosteum, the thick fibrous membrane covering the entire surface of a bone except its articular cartilage and serving as an attachment for muscles and tendons. The tibia-fibula is the portion of the two bones (tibia, the medial and larger bone, and fibula, the lateral and smaller bone) of the lower leg of bipeds or hindlimb of quadrupeds which are fused to form a single bone, e.g. the distal third of the rodent tibia and fibula. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a ollagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, PMID:20699128, PMID:857566, http://biomech2.me.berkeley.edu/cortical.html] synonym: "tibia/fibula cortical bone total cross-sectional area" EXACT [] synonym: "tibia-fibula cortical bone periosteal cross-sectional area" RELATED [] synonym: "tibio-fibular complex cortical bone total cross-sectional area" RELATED [] @@ -15106,7 +15106,7 @@ creation_date: 2013-07-29T12:43:11Z [Term] id: CMO:0001722 name: tibia-fibula cortical bone endosteal cross-sectional area -def: "The portion of the cross-sectional area of the tibia-fibula cortical bone that corresponds to the area circumscribed by the endosteum, the tissue lining the medullary or marrow cavity in the shaft of a long bone, i.e. the cross-sectional area of the medullary cavity of the tibia-fibula cortical bone. The cross-sectional area is the extent of a plane through, that is, perpendicular to the longest axis of the tibia-fibula, the portion of the two bones (tibia, the medial and larger bone, and fibula, the lateral and smaller bone) of the lower leg of bipeds or hindlimb of quadrupeds which are fused to form a single bone, e.g. the distal third of the rodent tibia and fibula. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, PMID:20699128, PMID:857566, Website:http\://biomech2.me.berkeley.edu/cortical.html] +def: "The portion of the cross-sectional area of the tibia-fibula cortical bone that corresponds to the area circumscribed by the endosteum, the tissue lining the medullary or marrow cavity in the shaft of a long bone, i.e. the cross-sectional area of the medullary cavity of the tibia-fibula cortical bone. The cross-sectional area is the extent of a plane through, that is, perpendicular to the longest axis of the tibia-fibula, the portion of the two bones (tibia, the medial and larger bone, and fibula, the lateral and smaller bone) of the lower leg of bipeds or hindlimb of quadrupeds which are fused to form a single bone, e.g. the distal third of the rodent tibia and fibula. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, PMID:20699128, PMID:857566, http://biomech2.me.berkeley.edu/cortical.html] synonym: "tibia/fibula cortical bone endosteal cross-sectional area" EXACT [] synonym: "tibio-fibular complex cortical bone endosteal cross-sectional area" RELATED [] synonym: "tibiofibular fusion cortical bone endosteal cross-sectional area" RELATED [] @@ -15127,7 +15127,7 @@ creation_date: 2013-07-29T13:06:14Z [Term] id: CMO:0001724 name: tibia total bone volume -def: "Measurement of the size of the three dimensional space occupied by the entire tibia, the medial and larger of the two bones of the lower leg of bipeds or hindlimb of quadrupeds which articulates with the femur, fibula, and talus, including the diaphysis composed of cortical bone and two epiphyses composed of trabecular bone." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Stedman:Stedmans_Medical_Dictionary, Wikipedia:http\://en.wikipedia.org/wiki/Tibia] +def: "Measurement of the size of the three dimensional space occupied by the entire tibia, the medial and larger of the two bones of the lower leg of bipeds or hindlimb of quadrupeds which articulates with the femur, fibula, and talus, including the diaphysis composed of cortical bone and two epiphyses composed of trabecular bone." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Stedman:Stedmans_Medical_Dictionary, https://en.wikipedia.org/wiki/Tibia] synonym: "tibial total bone volume" EXACT [] xref: MA:0001361 is_a: CMO:0001723 ! tibia volume measurement @@ -15137,7 +15137,7 @@ creation_date: 2013-07-29T13:14:23Z [Term] id: CMO:0001725 name: tibia cortical bone volume -def: "Measurement of the size of the three dimensional space occupied by the portion of the tibia composed of cortical bone. The tibia is the medial and larger of the two bones of the lower leg of bipeds or hindlimb of quadrupeds which articulates with the femur, fibula, and talus. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Stedman:Stedmans_Medical_Dictionary, Website:http\://biomech2.me.berkeley.edu/cortical.html] +def: "Measurement of the size of the three dimensional space occupied by the portion of the tibia composed of cortical bone. The tibia is the medial and larger of the two bones of the lower leg of bipeds or hindlimb of quadrupeds which articulates with the femur, fibula, and talus. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Stedman:Stedmans_Medical_Dictionary, http://biomech2.me.berkeley.edu/cortical.html] synonym: "tibial cortical bone volume" EXACT [] xref: MA:0001361 is_a: CMO:0001723 ! tibia volume measurement @@ -15156,7 +15156,7 @@ creation_date: 2013-07-29T13:21:48Z [Term] id: CMO:0001727 name: tibia cortical bone volume to tibia total bone volume ratio -def: "A calculated measurement in which the portion of the volume of the tibia corresponding to cortical bone is divided by the entire volume of the tibia and presented as a ratio, fraction, quotient or percentage. Volume is the measurement of the size of the three dimensional space occupied by an object. The tibia is the medial and larger of the two bones of the lower leg of bipeds or hindlimb of quadrupeds which articulates with the femur, fibula, and talus. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [Multiple_Dictionaries:http\://www.thefreedictionary.com/, Website:http\://biomech2.me.berkeley.edu/cortical.html] +def: "A calculated measurement in which the portion of the volume of the tibia corresponding to cortical bone is divided by the entire volume of the tibia and presented as a ratio, fraction, quotient or percentage. Volume is the measurement of the size of the three dimensional space occupied by an object. The tibia is the medial and larger of the two bones of the lower leg of bipeds or hindlimb of quadrupeds which articulates with the femur, fibula, and talus. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [http://www.thefreedictionary.com/, http://biomech2.me.berkeley.edu/cortical.html] synonym: "tibial cortical bone volume to tibial total bone volume ratio" EXACT [] is_a: CMO:0001726 ! calculated tibia bone volume created_by: JSmith @@ -15175,7 +15175,7 @@ creation_date: 2013-07-29T14:29:18Z [Term] id: CMO:0001729 name: trabecular volumetric bone mineral density -def: "Measurement of the mineral mass per unit volume of trabecular bone. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts. Trabecular or spongy bone is the porous type of bone found in the vertebrae and at all articulating joints, consisting of an irregular three-dimensional array of boney rods and plates (trabeculae) which themselves are composed of a composite material with bone marrow filling the spaces of the pores." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Website:http\://biomech2.me.berkeley.edu/trabecular.html] +def: "Measurement of the mineral mass per unit volume of trabecular bone. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts. Trabecular or spongy bone is the porous type of bone found in the vertebrae and at all articulating joints, consisting of an irregular three-dimensional array of boney rods and plates (trabeculae) which themselves are composed of a composite material with bone marrow filling the spaces of the pores." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, http://biomech2.me.berkeley.edu/trabecular.html] synonym: "trabecular vBMD" RELATED [] synonym: "trabecular volumetric BMD" RELATED [] is_a: CMO:0001553 ! volumetric bone mineral density @@ -15185,7 +15185,7 @@ creation_date: 2013-07-29T14:36:10Z [Term] id: CMO:0001730 name: cortical volumetric bone mineral density -def: "Measurement of the mineral mass per unit volume of corrical bone. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Website:http\://biomech2.me.berkeley.edu/cortical.html] +def: "Measurement of the mineral mass per unit volume of corrical bone. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts. Cortical or compact bone is the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, http://biomech2.me.berkeley.edu/cortical.html] synonym: "cortical vBMD" RELATED [] synonym: "cortical volumetric BMD" RELATED [] synonym: "volumetric bone mineral density of cortical bone" EXACT [] @@ -15234,7 +15234,7 @@ creation_date: 2013-07-30T11:29:48Z [Term] id: CMO:0001735 name: tibia stiffness -def: "A calculated measurement of the rigidity of the tibia, that is, the extent to which it resists deformation in response to an applied force, taken as the initial, i.e. the maximum, slope of the load-displacement curve. Tibia is the medial and larger of the two bones of the lower leg of bipeds or hindlimb of quadrupeds which articulates with the femur, fibula, and talus. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:16059631, Stedman:Stedmans_Medical_Dictionary, Wikipedia:http\://en.wikipedia.org/wiki/Stiffness] +def: "A calculated measurement of the rigidity of the tibia, that is, the extent to which it resists deformation in response to an applied force, taken as the initial, i.e. the maximum, slope of the load-displacement curve. Tibia is the medial and larger of the two bones of the lower leg of bipeds or hindlimb of quadrupeds which articulates with the femur, fibula, and talus. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:16059631, Stedman:Stedmans_Medical_Dictionary, https://en.wikipedia.org/wiki/Stiffness] synonym: "tibial stiffness" EXACT [] xref: MA:0001361 is_a: CMO:0001673 ! bone stiffness @@ -15272,7 +15272,7 @@ creation_date: 2013-07-30T15:23:43Z [Term] id: CMO:0001738 name: brain spike-and-wave discharge measurement -def: "Measurement of a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Spike_and_Wave] +def: "Measurement of a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Spike_and_Wave] synonym: "brain spike-wave activity measurement" RELATED [] synonym: "brain spike-wave discharge measurement" EXACT [] synonym: "brain SWD measurement" RELATED [] @@ -15283,7 +15283,7 @@ creation_date: 2013-07-30T15:58:09Z [Term] id: CMO:0001739 name: brain spike-and-wave discharge rate -def: "Measurement of the number of periods of spike-and-wave discharges occurring per unit of time. A spike-and-wave discharge is a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the number of periods of spike-and-wave discharges occurring per unit of time. A spike-and-wave discharge is a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain spike-wave activity rate" RELATED [] synonym: "brain spike-wave discharge rate" EXACT [] synonym: "brain SWD rate" RELATED [] @@ -15295,7 +15295,7 @@ creation_date: 2013-07-30T16:16:19Z [Term] id: CMO:0001740 name: brain total spike-and-wave discharge duration -def: "Measurement of the cumulated duration of spikes and waves occurring per unit of time during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the cumulated duration of spikes and waves occurring per unit of time during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain total spike-wave activity duration" RELATED [] synonym: "brain total spike-wave discharge duration" EXACT [] synonym: "brain total SWD duration" RELATED [] @@ -15307,7 +15307,7 @@ creation_date: 2013-07-30T16:37:00Z [Term] id: CMO:0001741 name: brain spike-and-wave discharge amplitude -def: "Measurement of the maximum deviation from the baseline position of the electrical signal during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs. Such deviations can be either positive or negative, i.e. amplitude is the distance from rest (baseline) to crest or from the rest position to the trough position." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Website:http\://www.physicsclassroom.com/class/waves/u10l2a.cfm#amplitude, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the maximum deviation from the baseline position of the electrical signal during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs. Such deviations can be either positive or negative, i.e. amplitude is the distance from rest (baseline) to crest or from the rest position to the trough position." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, http://www.physicsclassroom.com/class/waves/u10l2a.cfm#amplitude, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain spike-wave activity amplitude" RELATED [] synonym: "brain spike-wave discharge amplitude" EXACT [] synonym: "brain SWD amplitude" RELATED [] @@ -15318,7 +15318,7 @@ creation_date: 2013-07-30T16:41:41Z [Term] id: CMO:0001742 name: brain spike-and-wave discharge frequency -def: "Measurement of the number of individual spike-and-wave discharge cycles occurring per second. A spike-and-wave discharge is a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.biogetic.com/research.html, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the number of individual spike-and-wave discharge cycles occurring per second. A spike-and-wave discharge is a series of regular, symmetrical, generalized abnormal electrical discharges in the brain, the portion of the central nervous system enclosed within the cranium which is composed of gray matter and white matter and is the primary center for the regulation and control of bodily activities, receiving and interpreting sensory impulses, and transmitting information to the muscles and body organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.biogetic.com/research.html, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain spike-wave activity frequency" RELATED [] synonym: "brain spike-wave discharge frequency" EXACT [] synonym: "brain SWD frequency" RELATED [] @@ -15329,7 +15329,7 @@ creation_date: 2013-07-30T17:05:38Z [Term] id: CMO:0001743 name: absolute change in left ventricular diastolic blood pressure -def: "The difference in left ventricular diastolic blood pressure between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in left ventricular diastolic blood pressure between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in LVDBP" RELATED [] is_a: CMO:0000006 ! left ventricular diastolic blood pressure @@ -15350,7 +15350,7 @@ creation_date: 2013-07-31T15:17:53Z [Term] id: CMO:0001745 name: maximum rate of positive change in left ventricular blood pressure -def: "A calculated measurement that is used as an index to characterize the contractile ability of the heart. It is believed that maximum dP/dt is a reasonable index of the initial velocity of myocardial contraction." [Website:https\://cdac.pulsemetric.com/Reports/HemodynamicDefs.htm] +def: "A calculated measurement that is used as an index to characterize the contractile ability of the heart. It is believed that maximum dP/dt is a reasonable index of the initial velocity of myocardial contraction." [https://cdac.pulsemetric.com/Reports/HemodynamicDefs.htm] synonym: "LV +dP/dt Max" RELATED [] synonym: "peak +LVdP/dt" RELATED [] synonym: "rate of maximum positive change in left ventricular blood pressure" RELATED [] @@ -15449,7 +15449,7 @@ creation_date: 2013-08-01T16:27:21Z [Term] id: CMO:0001756 name: pituicyte count -def: "The enumeration, i.e. measurement of the total number, of pituicytes, the glial-type cells of the posterior pituitary whose main role is to assist in the storage and release of neurohypophysial hormones such as oxytocin and vasopressin, in a specified sample of pituitary gland, the small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Webster:Random_House_Kernerman_Websters_College_Dictionary_2010, Wikipedia:http\://en.wikipedia.org/wiki/Pituicyte] +def: "The enumeration, i.e. measurement of the total number, of pituicytes, the glial-type cells of the posterior pituitary whose main role is to assist in the storage and release of neurohypophysial hormones such as oxytocin and vasopressin, in a specified sample of pituitary gland, the small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Webster:Random_House_Kernerman_Websters_College_Dictionary_2010, https://en.wikipedia.org/wiki/Pituicyte] synonym: "pituitary gland cell count" BROAD [] is_a: CMO:0000614 ! pituitary gland morphological measurement is_a: CMO:0002163 ! pituicyte measurement @@ -15459,7 +15459,7 @@ creation_date: 2013-08-01T16:44:37Z [Term] id: CMO:0001757 name: lactotroph count to total pituicyte count ratio -def: "A calculated measurement in which the number of lactotrophs in a specified sample of pituitary gland is divided by the total number of pituicytes in that sample and presented as a ratio, fraction, quotient or percentage. Lactotrophs are acidophils of the adenohypophysis, the anterior glandular lobe of the pituitary gland, that secrete prolactin. Pituicytes are the glial-type cells of the posterior pituitary whose main role is to assist in the storage and release of neurohypophysial hormones such as oxytocin and vasopressin. The pituitary gland is the small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Pituicyte] +def: "A calculated measurement in which the number of lactotrophs in a specified sample of pituitary gland is divided by the total number of pituicytes in that sample and presented as a ratio, fraction, quotient or percentage. Lactotrophs are acidophils of the adenohypophysis, the anterior glandular lobe of the pituitary gland, that secrete prolactin. Pituicytes are the glial-type cells of the posterior pituitary whose main role is to assist in the storage and release of neurohypophysial hormones such as oxytocin and vasopressin. The pituitary gland is the small, oval endocrine gland attached to the base of the vertebrate brain and consisting of an anterior and posterior lobe, the secretions of which control the other endocrine glands and influence growth, metabolism, and maturation." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Pituicyte] synonym: "lactotroph density" RELATED [] synonym: "prolactin-positive cell count to total pituicyte count ratio" RELATED [] is_a: CMO:0001755 ! calculated pituitary gland morphological measurement @@ -15510,7 +15510,7 @@ creation_date: 2013-08-06T17:02:30Z [Term] id: CMO:0001762 name: drink intake weight -def: "Measurement of the weight or heaviness of the drink, that is, the liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed in a specified period of time." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, YourDictionary:http\://www.yourdictionary.com/drink] +def: "Measurement of the weight or heaviness of the drink, that is, the liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed in a specified period of time." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, http://www.yourdictionary.com/drink] is_a: CMO:0000771 ! drink intake measurement created_by: JSmith creation_date: 2013-08-06T17:17:00Z @@ -15518,7 +15518,7 @@ creation_date: 2013-08-06T17:17:00Z [Term] id: CMO:0001763 name: ethanol intake weight -def: "Measurement of the weight or heaviness of a solution of ethanol, the colorless, volatile, flammable liquid, CH3CH2OH, produced by yeast fermentation of carbohydrates or synthesized by hydration of ethylene, that is consumed as a drink, a liquid brought into the mouth and swallowed to quench thirst, for nourishment, etc., in a specified period of time." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Webster:Random_House_Kernerman_Websters_College_Dictionary_2010, YourDictionary:http\://www.yourdictionary.com/drink] +def: "Measurement of the weight or heaviness of a solution of ethanol, the colorless, volatile, flammable liquid, CH3CH2OH, produced by yeast fermentation of carbohydrates or synthesized by hydration of ethylene, that is consumed as a drink, a liquid brought into the mouth and swallowed to quench thirst, for nourishment, etc., in a specified period of time." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Webster:Random_House_Kernerman_Websters_College_Dictionary_2010, http://www.yourdictionary.com/drink] synonym: "alcohol intake weight" RELATED [] is_a: CMO:0001762 ! drink intake weight created_by: JSmith @@ -15527,7 +15527,7 @@ creation_date: 2013-08-06T17:26:24Z [Term] id: CMO:0001764 name: calculated ethanol intake weight -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the weight or heaviness of a solution of ethanol, the colorless, volatile, flammable liquid, CH3CH2OH, produced by yeast fermentation of carbohydrates or synthesized by hydration of ethylene, that is consumed as a drink, a liquid brought into the mouth and swallowed to quench thirst, for nourishment, etc., in a specified period of time." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the weight or heaviness of a solution of ethanol, the colorless, volatile, flammable liquid, CH3CH2OH, produced by yeast fermentation of carbohydrates or synthesized by hydration of ethylene, that is consumed as a drink, a liquid brought into the mouth and swallowed to quench thirst, for nourishment, etc., in a specified period of time." [http://www.thefreedictionary.com/] synonym: "calculated alcohol intake weight" BROAD [] synonym: "Not4Curation" RELATED [] is_a: CMO:0001763 ! ethanol intake weight @@ -15538,7 +15538,7 @@ creation_date: 2013-08-06T17:29:45Z [Term] id: CMO:0001765 name: ethanol intake weight to body weight ratio -def: "A calculated measurement in which ethanol intake weight is divided by total weight of the body and presented as a ratio, fraction, quotient or percentage, thus normalizing it to body weight and, by extension, to the size of the organism. Ethanol intake weight is the heaviness of a solution of ethanol, the colorless, volatile, flammable liquid, CH3CH2OH, produced by yeast fermentation of carbohydrates or synthesized by hydration of ethylene, that is consumed as a drink, a liquid brought into the mouth and swallowed to quench thirst, for nourishment, etc., in a specified period of time. Body weight is the heaviness or degree to which a body is drawn toward the earth by gravity." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated measurement in which ethanol intake weight is divided by total weight of the body and presented as a ratio, fraction, quotient or percentage, thus normalizing it to body weight and, by extension, to the size of the organism. Ethanol intake weight is the heaviness of a solution of ethanol, the colorless, volatile, flammable liquid, CH3CH2OH, produced by yeast fermentation of carbohydrates or synthesized by hydration of ethylene, that is consumed as a drink, a liquid brought into the mouth and swallowed to quench thirst, for nourishment, etc., in a specified period of time. Body weight is the heaviness or degree to which a body is drawn toward the earth by gravity." [http://www.thefreedictionary.com/] synonym: "alcohol intake weight to body weight ratio" RELATED [] is_a: CMO:0001764 ! calculated ethanol intake weight created_by: JSmith @@ -15564,7 +15564,7 @@ creation_date: 2013-08-12T16:31:27Z [Term] id: CMO:0001768 name: quinine drink intake volume -def: "Measurement of the size of the three dimensional space occupied by a solution of quinine consumed as a drink, a liquid that is brought into the mouth and swallowed to quench thirst and/or for nourishment. Quinine is a bitter alkaloid of cinchona that has antimalarial, analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties, and decreases the excitability of the motor end plate." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, YourDictionary:http\://www.yourdictionary.com/drink] +def: "Measurement of the size of the three dimensional space occupied by a solution of quinine consumed as a drink, a liquid that is brought into the mouth and swallowed to quench thirst and/or for nourishment. Quinine is a bitter alkaloid of cinchona that has antimalarial, analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties, and decreases the excitability of the motor end plate." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.yourdictionary.com/drink] is_a: CMO:0000773 ! drink intake volume created_by: JSmith creation_date: 2013-08-12T17:06:58Z @@ -15572,7 +15572,7 @@ creation_date: 2013-08-12T17:06:58Z [Term] id: CMO:0001769 name: calculated quinine drink intake volume -def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the size of the three dimensional space occupied by a solution of quinine consumed as a drink, a liquid that is brought into the mouth and swallowed to quench thirst and/or for nourishment. Quinine is a bitter alkaloid of cinchona that has antimalarial, analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties, and decreases the excitability of the motor end plate." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the size of the three dimensional space occupied by a solution of quinine consumed as a drink, a liquid that is brought into the mouth and swallowed to quench thirst and/or for nourishment. Quinine is a bitter alkaloid of cinchona that has antimalarial, analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties, and decreases the excitability of the motor end plate." [http://www.thefreedictionary.com/] synonym: "Not4Curation" RELATED [] is_a: CMO:0001768 ! quinine drink intake volume is_a: CMO:0002333 ! calculated drink intake volume @@ -15582,7 +15582,7 @@ creation_date: 2013-08-12T17:11:08Z [Term] id: CMO:0001770 name: combined water and quinine-water intake to total water only intake ratio -def: "A calculated measurement in which the entire volume of drink consumed during a specified period when that drink consists of both water with no additives and water with added quinine, is divided by the entire volume of drink consumed during a separate but equivalent period when that drink consists only of water with no additives, and the result is presented as a ratio, fraction, quotient or percentage. The volume of drink is the size of the three dimensional space occupied by a liquid that is brought into the mouth and swallowed to quench thirst and/or for nourishment. Quinine-water is quinine, a bitter alkaloid of cinchona that has antimalarial, analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties and that decreases the excitability of the motor end plate, dissolved at a specified concentration in water, the clear, colorless, odorless, tasteless liquid each molecule of which contains one atom of oxygen and two atoms of hydrogen (H2O)." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated measurement in which the entire volume of drink consumed during a specified period when that drink consists of both water with no additives and water with added quinine, is divided by the entire volume of drink consumed during a separate but equivalent period when that drink consists only of water with no additives, and the result is presented as a ratio, fraction, quotient or percentage. The volume of drink is the size of the three dimensional space occupied by a liquid that is brought into the mouth and swallowed to quench thirst and/or for nourishment. Quinine-water is quinine, a bitter alkaloid of cinchona that has antimalarial, analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties and that decreases the excitability of the motor end plate, dissolved at a specified concentration in water, the clear, colorless, odorless, tasteless liquid each molecule of which contains one atom of oxygen and two atoms of hydrogen (H2O)." [http://www.thefreedictionary.com/] synonym: "quinine index" RELATED [] synonym: "total water plus quinine-water intake to total water only intake ratio" EXACT [] is_a: CMO:0001769 ! calculated quinine drink intake volume @@ -15632,7 +15632,7 @@ creation_date: 2013-09-11T13:00:50Z [Term] id: CMO:0001775 name: absolute change in food intake -def: "A calculated measurement of the difference in the amount of food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body between two points in time or two conditions, expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "A calculated measurement of the difference in the amount of food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body between two points in time or two conditions, expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0001774 ! calculated food intake measurement created_by: JSmith @@ -15641,7 +15641,7 @@ creation_date: 2013-09-11T14:22:01Z [Term] id: CMO:0001776 name: absolute change in food intake weight -def: "A calculated measurement of the difference in the weight of food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body between two points in time or two conditions, expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. Weight is the vertical force experienced by a mass as a result of gravitation." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "A calculated measurement of the difference in the weight of food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body between two points in time or two conditions, expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. Weight is the vertical force experienced by a mass as a result of gravitation." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0001775 ! absolute change in food intake created_by: JSmith @@ -15650,7 +15650,7 @@ creation_date: 2013-09-11T14:24:12Z [Term] id: CMO:0001777 name: absolute change in food intake volume -def: "A calculated measurement of the difference in the volume, i.e., the size of the three dimensional space occupied by the food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body between two points in time or two conditions, expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, American_Heritage:The_American_Heritage_Science_Dictionary_2005, Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "A calculated measurement of the difference in the volume, i.e., the size of the three dimensional space occupied by the food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body between two points in time or two conditions, expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, American_Heritage:The_American_Heritage_Science_Dictionary_2005, Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0001775 ! absolute change in food intake created_by: JSmith @@ -15659,7 +15659,7 @@ creation_date: 2013-09-11T14:25:30Z [Term] id: CMO:0001778 name: percent change in food intake -def: "A calculated measurement of the relative difference in the amount of food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body, between a treated state and a control state or between two points in time, expressed as a percentage." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Percent_change] +def: "A calculated measurement of the relative difference in the amount of food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body, between a treated state and a control state or between two points in time, expressed as a percentage." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Percent_change] synonym: "relative change in food intake" RELATED [] is_a: CMO:0001774 ! calculated food intake measurement created_by: JSmith @@ -15668,7 +15668,7 @@ creation_date: 2013-09-11T14:28:11Z [Term] id: CMO:0001779 name: percent change in food intake volume -def: "A calculated measurement of the relative difference in the volume, i.e., the size of the three dimensional space occupied by the food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body, between a treated state and a control state or between two points in time, expressed as a percentage." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Percent_change] +def: "A calculated measurement of the relative difference in the volume, i.e., the size of the three dimensional space occupied by the food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body, between a treated state and a control state or between two points in time, expressed as a percentage." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Percent_change] synonym: "relative change in food intake volume" RELATED [] is_a: CMO:0001778 ! percent change in food intake is_a: CMO:0002220 ! calculated food intake volume measurement @@ -15678,7 +15678,7 @@ creation_date: 2013-09-11T14:30:00Z [Term] id: CMO:0001780 name: percent change in food intake weight -def: "A calculated measurement of the relative difference in the weight of food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body, between a treated state and a control state or between two points in time, expressed as a percentage. Weight is the vertical force experienced by a mass as a result of gravitation." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Percent_change] +def: "A calculated measurement of the relative difference in the weight of food (material, usually of plant or animal origin, that contains essential nutrients such as carbohydrates, fats, proteins, vitamins, and/or minerals and that is ingested and assimilated by an organism to produce energy, stimulate growth, and maintain life) taken in for utilization by the body, between a treated state and a control state or between two points in time, expressed as a percentage. Weight is the vertical force experienced by a mass as a result of gravitation." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Percent_change] synonym: "relative change in food intake weight" RELATED [] is_a: CMO:0001778 ! percent change in food intake created_by: JSmith @@ -15798,7 +15798,7 @@ creation_date: 2013-09-20T16:12:10Z [Term] id: CMO:0001792 name: combined water and saccharin-water intake to total water only intake ratio -def: "A calculated measurement in which the entire volume of drink consumed during a specified period when that drink consists of both water with no additives and water with added saccharin, is divided by the entire volume of drink consumed during a separate but equivalent period when that drink consists only of water with no additives, and the result is presented as a ratio, fraction, quotient or percentage. The volume of drink is the size of the three dimensional space occupied by a liquid that is brought into the mouth and swallowed to quench thirst and/or for nourishment. Saccharin-water is saccharin, a cyclic imine of 2-sulfobenzoic acid which is 500 times sweeter than sugar and used as a nonnutritive sweetener, dissolved at a specified concentration in water, the clear, colorless, odorless, tasteless liquid each molecule of which contains one atom of oxygen and two atoms of hydrogen (H2O)." [Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated measurement in which the entire volume of drink consumed during a specified period when that drink consists of both water with no additives and water with added saccharin, is divided by the entire volume of drink consumed during a separate but equivalent period when that drink consists only of water with no additives, and the result is presented as a ratio, fraction, quotient or percentage. The volume of drink is the size of the three dimensional space occupied by a liquid that is brought into the mouth and swallowed to quench thirst and/or for nourishment. Saccharin-water is saccharin, a cyclic imine of 2-sulfobenzoic acid which is 500 times sweeter than sugar and used as a nonnutritive sweetener, dissolved at a specified concentration in water, the clear, colorless, odorless, tasteless liquid each molecule of which contains one atom of oxygen and two atoms of hydrogen (H2O)." [http://www.thefreedictionary.com/] synonym: "saccharin index" RELATED [] synonym: "total water plus saccharin-water intake to total water only intake ratio" EXACT [] is_a: CMO:0001600 ! calculated saccharin drink intake volume @@ -15856,7 +15856,7 @@ creation_date: 2013-09-26T12:13:07Z [Term] id: CMO:0001797 name: colorectal tumor surface area measurement -def: "A measurement of the two-dimensional extent of a planar region comprising the superficial or external aspect of one or more colorectal tumors, abnormal growths of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function, which occur in the large intestine, the distal portion of the alimentary canal, especially in the colon and/or rectum, the segment of the large intestine between the cecum and the anal canal." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the two-dimensional extent of a planar region comprising the superficial or external aspect of one or more colorectal tumors, abnormal growths of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function, which occur in the large intestine, the distal portion of the alimentary canal, especially in the colon and/or rectum, the segment of the large intestine between the cecum and the anal canal." [ISBN:978-1416049982, http://www.thefreedictionary.com/] synonym: "colorectal neoplasm surface area measurement" RELATED [] xref: MESH:D015179 is_a: CMO:0001793 ! colorectal tumor measurement @@ -15866,7 +15866,7 @@ creation_date: 2013-09-26T12:16:42Z [Term] id: CMO:0001798 name: malignant colorectal tumor surface area measurement -def: "A measurement of the two-dimensional extent of a planar region comprising the superficial or external aspect of one or more malignant colorectal tumors, abnormal growths of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function, which display the properties of anaplasia, invasiveness and metastasis, and which occur in the large intestine, the distal portion of the alimentary canal, especially in the colon and/or rectum, the segment of the large intestine between the cecum and the anal canal." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the two-dimensional extent of a planar region comprising the superficial or external aspect of one or more malignant colorectal tumors, abnormal growths of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function, which display the properties of anaplasia, invasiveness and metastasis, and which occur in the large intestine, the distal portion of the alimentary canal, especially in the colon and/or rectum, the segment of the large intestine between the cecum and the anal canal." [ISBN:978-1416049982, http://www.thefreedictionary.com/] synonym: "colorectal adenocarcinoma surface area measurement" RELATED [] synonym: "malignant colorectal neoplasm surface area measurement" RELATED [] xref: MESH:D015179 @@ -15878,7 +15878,7 @@ creation_date: 2013-09-26T12:23:59Z [Term] id: CMO:0001799 name: benign colorectal tumor surface area measurement -def: "A measurement of the two-dimensional extent of a planar region comprising the superficial or external aspect of one or more benign colorectal tumors, abnormal growths of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function, which are generally stable, treatable, circumscribed (that is, not displaying invasiveness or metastasis), and in a relatively normal state of differentiation, and which occur in the large intestine, the distal portion of the alimentary canal, especially in the colon and/or rectum, the segment of the large intestine between the cecum and the anal canal." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A measurement of the two-dimensional extent of a planar region comprising the superficial or external aspect of one or more benign colorectal tumors, abnormal growths of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function, which are generally stable, treatable, circumscribed (that is, not displaying invasiveness or metastasis), and in a relatively normal state of differentiation, and which occur in the large intestine, the distal portion of the alimentary canal, especially in the colon and/or rectum, the segment of the large intestine between the cecum and the anal canal." [ISBN:978-1416049982, http://www.thefreedictionary.com/] synonym: "benign colorectal neoplasm surface area measurement" RELATED [] synonym: "colorectal adenoma surface area measurement" RELATED [] xref: MESH:D015179 @@ -15998,7 +15998,7 @@ creation_date: 2013-09-26T18:23:32Z [Term] id: CMO:0001809 name: calculated coat/hair color measurement -def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the color of the hair, wool, or fur of an organism, that is, of either a single cylindrical, keratinized, often pigmented filament characteristically growing from the epidermis of a mammal, or of the aggregate of all such filaments. Color is property of a surface or substance due to absorption of certain light rays and reflection of others within the range of wavelengths (roughly 370-760 nm) adequate to excite the retinal receptors." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the color of the hair, wool, or fur of an organism, that is, of either a single cylindrical, keratinized, often pigmented filament characteristically growing from the epidermis of a mammal, or of the aggregate of all such filaments. Color is property of a surface or substance due to absorption of certain light rays and reflection of others within the range of wavelengths (roughly 370-760 nm) adequate to excite the retinal receptors." [ISBN:978-1416049982, http://www.thefreedictionary.com/] is_a: CMO:0001808 ! coat/hair color measurement created_by: JSmith creation_date: 2013-09-26T18:25:42Z @@ -16006,7 +16006,7 @@ creation_date: 2013-09-26T18:25:42Z [Term] id: CMO:0001810 name: pigmented coat/hair area to total coat/hair area ratio -def: "A calculated measurement in which the value representing the two-dimensional extent of the planar region of the body surface occupied by hair, wool, or fur (cylindrical, keratinized, often pigmented filaments characteristically growing from the epidermis of a mammal) containing proteins or other substances which give that hair the appearance of color, is divided by the value representing the entirety of the two-dimensional extent of the planar region of the body surface of the organism occupied by hair, wool, or fur with or without color, and presented as a ratio, fraction, quotient or percentage. Color is property of a surface or substance due to absorption of certain light rays and reflection of others within the range of wavelengths (roughly 370-760 nm) adequate to excite the retinal receptors." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated measurement in which the value representing the two-dimensional extent of the planar region of the body surface occupied by hair, wool, or fur (cylindrical, keratinized, often pigmented filaments characteristically growing from the epidermis of a mammal) containing proteins or other substances which give that hair the appearance of color, is divided by the value representing the entirety of the two-dimensional extent of the planar region of the body surface of the organism occupied by hair, wool, or fur with or without color, and presented as a ratio, fraction, quotient or percentage. Color is property of a surface or substance due to absorption of certain light rays and reflection of others within the range of wavelengths (roughly 370-760 nm) adequate to excite the retinal receptors." [ISBN:978-1416049982, http://www.thefreedictionary.com/] is_a: CMO:0001809 ! calculated coat/hair color measurement created_by: JSmith creation_date: 2013-09-26T18:26:34Z @@ -16014,7 +16014,7 @@ creation_date: 2013-09-26T18:26:34Z [Term] id: CMO:0001811 name: pigmented dorsal coat/hair area to total dorsal coat/hair area ratio -def: "A calculated measurement in which the value representing the two-dimensional extent of the planar region of the dorsal half of the body surface occupied by hair, wool, or fur (cylindrical, keratinized, often pigmented filaments characteristically growing from the epidermis of a mammal) containing proteins or other substances which give that hair the appearance of color, is divided by the value representing the entirety of the two-dimensional extent of the planar region of the dorsal half of the body surface of the organism occupied by hair, wool, or fur with or without color, and presented as a ratio, fraction, quotient or percentage. The dorsal half of the body is the approximately fifty percent of the body closest to the back and, in vertebrates, containing the spine. Color is property of a surface or substance due to absorption of certain light rays and reflection of others within the range of wavelengths (roughly 370-760 nm) adequate to excite the retinal receptors." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated measurement in which the value representing the two-dimensional extent of the planar region of the dorsal half of the body surface occupied by hair, wool, or fur (cylindrical, keratinized, often pigmented filaments characteristically growing from the epidermis of a mammal) containing proteins or other substances which give that hair the appearance of color, is divided by the value representing the entirety of the two-dimensional extent of the planar region of the dorsal half of the body surface of the organism occupied by hair, wool, or fur with or without color, and presented as a ratio, fraction, quotient or percentage. The dorsal half of the body is the approximately fifty percent of the body closest to the back and, in vertebrates, containing the spine. Color is property of a surface or substance due to absorption of certain light rays and reflection of others within the range of wavelengths (roughly 370-760 nm) adequate to excite the retinal receptors." [ISBN:978-1416049982, http://www.thefreedictionary.com/] is_a: CMO:0001810 ! pigmented coat/hair area to total coat/hair area ratio created_by: JSmith creation_date: 2013-09-26T18:27:51Z @@ -16022,7 +16022,7 @@ creation_date: 2013-09-26T18:27:51Z [Term] id: CMO:0001812 name: pigmented ventral coat/hair area to total ventral coat/hair area ratio -def: "A calculated measurement in which the value representing the two-dimensional extent of the planar region of the ventral half of the body surface occupied by hair, wool, or fur (cylindrical, keratinized, often pigmented filaments characteristically growing from the epidermis of a mammal) containing proteins or other substances which give that hair the appearance of color, is divided by the value representing the entirety of the two-dimensional extent of the planar region of the ventral half of the body surface of the organism occupied by hair, wool, or fur with or without color, and presented as a ratio, fraction, quotient or percentage. The ventral half of the body is the approximately fifty percent of the body that is closest to the anterior aspect of the human body or the lower surface of the body of an animal, and in vertebrates, furthest from the spine. Color is property of a surface or substance due to absorption of certain light rays and reflection of others within the range of wavelengths (roughly 370-760 nm) adequate to excite the retinal receptors." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/] +def: "A calculated measurement in which the value representing the two-dimensional extent of the planar region of the ventral half of the body surface occupied by hair, wool, or fur (cylindrical, keratinized, often pigmented filaments characteristically growing from the epidermis of a mammal) containing proteins or other substances which give that hair the appearance of color, is divided by the value representing the entirety of the two-dimensional extent of the planar region of the ventral half of the body surface of the organism occupied by hair, wool, or fur with or without color, and presented as a ratio, fraction, quotient or percentage. The ventral half of the body is the approximately fifty percent of the body that is closest to the anterior aspect of the human body or the lower surface of the body of an animal, and in vertebrates, furthest from the spine. Color is property of a surface or substance due to absorption of certain light rays and reflection of others within the range of wavelengths (roughly 370-760 nm) adequate to excite the retinal receptors." [ISBN:978-1416049982, http://www.thefreedictionary.com/] is_a: CMO:0001810 ! pigmented coat/hair area to total coat/hair area ratio created_by: JSmith creation_date: 2013-09-26T18:28:52Z @@ -16030,7 +16030,7 @@ creation_date: 2013-09-26T18:28:52Z [Term] id: CMO:0001813 name: ratio of insulin-positive cell area to total area of duodenal region of pancreas -def: "A calculated measurement in which the value representing the two-dimensional extent of the part(s) of the head region of the pancreas (that is, the portion of the pancreas which lies closest to the duodenum, the first segment of the small intestine) in which insulin, the major, fuel-regulating peptide hormone that promotes storage of glucose and inhibits lipolysis and gluconeogenesis, can be detected is divided by the value representing the entirety of the two-dimensional extent of the head region of the pancreas, and presented as a ratio, fraction, quotient or percentage. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "A calculated measurement in which the value representing the two-dimensional extent of the part(s) of the head region of the pancreas (that is, the portion of the pancreas which lies closest to the duodenum, the first segment of the small intestine) in which insulin, the major, fuel-regulating peptide hormone that promotes storage of glucose and inhibits lipolysis and gluconeogenesis, can be detected is divided by the value representing the entirety of the two-dimensional extent of the head region of the pancreas, and presented as a ratio, fraction, quotient or percentage. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Pancreas] synonym: "ratio of duodenal IPCA" RELATED [] synonym: "ratio of insulin-positive cell area to total area of head region of pancreas" RELATED [] synonym: "ratio of IPCA to total area of duodenal region of pancreas" RELATED [] @@ -16042,7 +16042,7 @@ creation_date: 2013-10-04T16:52:04Z [Term] id: CMO:0001814 name: ratio of insulin-positive cell area to total area of splenic region of pancreas -def: "A calculated measurement in which the value representing the two-dimensional extent of the part(s) of the tail region of the pancreas (that is, the portion of the pancreas which lies furthest from the major pancreatic duct and closest to the spleen, the highly vascular lymphoid organ which serves to store blood, disintegrate old blood cells, filter foreign substances from the blood, and produce lymphocytes) in which insulin, the major, fuel-regulating peptide hormone that promotes storage of glucose and inhibits lipolysis and gluconeogenesis, can be detected is divided by the value representing the entirety of the two-dimensional extent of the tail region of the pancreas, and presented as a ratio, fraction, quotient or percentage. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "A calculated measurement in which the value representing the two-dimensional extent of the part(s) of the tail region of the pancreas (that is, the portion of the pancreas which lies furthest from the major pancreatic duct and closest to the spleen, the highly vascular lymphoid organ which serves to store blood, disintegrate old blood cells, filter foreign substances from the blood, and produce lymphocytes) in which insulin, the major, fuel-regulating peptide hormone that promotes storage of glucose and inhibits lipolysis and gluconeogenesis, can be detected is divided by the value representing the entirety of the two-dimensional extent of the tail region of the pancreas, and presented as a ratio, fraction, quotient or percentage. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Pancreas] synonym: "ratio of insulin-positive cell area to total area of tail region of pancreas" RELATED [] synonym: "ratio of IPCA to total area of pancreas tail region" RELATED [] synonym: "ratio of IPCA to total area of splenic region of pancreas" RELATED [] @@ -16054,7 +16054,7 @@ creation_date: 2013-10-04T16:54:04Z [Term] id: CMO:0001815 name: pancreatic islet weight -def: "Measurement of the weight, i.e., the heaviness or the force with which an object is drawn toward the earth by gravity, of a single pancreatic islet or of the total of all of the islets in the entire pancreas or in a specified part thereof. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "Measurement of the weight, i.e., the heaviness or the force with which an object is drawn toward the earth by gravity, of a single pancreatic islet or of the total of all of the islets in the entire pancreas or in a specified part thereof. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Pancreas] is_a: CMO:0001052 ! pancreatic islet morphological measurement created_by: JSmith creation_date: 2013-10-11T11:17:13Z @@ -16062,7 +16062,7 @@ creation_date: 2013-10-11T11:17:13Z [Term] id: CMO:0001816 name: calculated pancreatic islet weight -def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the weight, i.e., the heaviness or the force with which an object is drawn toward the earth by gravity, of a single pancreatic islet or of the total of all of the islets in the entire pancreas or in a specified part thereof. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the weight, i.e., the heaviness or the force with which an object is drawn toward the earth by gravity, of a single pancreatic islet or of the total of all of the islets in the entire pancreas or in a specified part thereof. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Pancreas] is_a: CMO:0001815 ! pancreatic islet weight created_by: JSmith creation_date: 2013-10-11T16:20:49Z @@ -16070,7 +16070,7 @@ creation_date: 2013-10-11T16:20:49Z [Term] id: CMO:0001817 name: calculated total pancreatic islet beta cell weight -def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the weight (the heaviness or the force with which an object is drawn toward the earth by gravity) of the entirety of the islet beta cells in the pancreas. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the weight (the heaviness or the force with which an object is drawn toward the earth by gravity) of the entirety of the islet beta cells in the pancreas. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin." [ISBN:978-1416049982, http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Pancreas] synonym: "calculated islet beta cell mass of total pancreas" RELATED [] is_a: CMO:0001816 ! calculated pancreatic islet weight created_by: JSmith @@ -16079,7 +16079,7 @@ creation_date: 2013-10-11T16:22:41Z [Term] id: CMO:0001818 name: calculated weight of islet beta cells in duodenal region of pancreas -def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the weight (the heaviness or the force with which an object is drawn toward the earth by gravity) of the islet beta cells in the head region of the pancreas, the portion of the pancreas which lies closest to the duodenum, the first segment of the small intestine, and contains the major pancreatic duct. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the weight (the heaviness or the force with which an object is drawn toward the earth by gravity) of the islet beta cells in the head region of the pancreas, the portion of the pancreas which lies closest to the duodenum, the first segment of the small intestine, and contains the major pancreatic duct. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin." [ISBN:978-1416049982, http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Pancreas] synonym: "calculated islet beta cell mass of duodenal region of pancreas" RELATED [] synonym: "calculated weight of islet beta cells in the head region of pancreas" EXACT [] relationship: part_of CMO:0001817 ! calculated total pancreatic islet beta cell weight @@ -16089,7 +16089,7 @@ creation_date: 2013-10-11T16:25:01Z [Term] id: CMO:0001819 name: calculated weight of islet beta cells in splenic region of pancreas -def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the weight (the heaviness or the force with which an object is drawn toward the earth by gravity) of the islet beta cells in the tail region of the pancreas (that is, the portion of the pancreas which lies furthest from the major pancreatic duct and closest to the spleen, the highly vascular lymphoid organ which serves to store blood, disintegrate old blood cells, filter foreign substances from the blood, and produce lymphocytes). The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "A measurement, which has been normalized, adjusted or derived by a mathematical process or computation, of the weight (the heaviness or the force with which an object is drawn toward the earth by gravity) of the islet beta cells in the tail region of the pancreas (that is, the portion of the pancreas which lies furthest from the major pancreatic duct and closest to the spleen, the highly vascular lymphoid organ which serves to store blood, disintegrate old blood cells, filter foreign substances from the blood, and produce lymphocytes). The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin." [ISBN:978-1416049982, http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Pancreas] synonym: "calculated islet beta cell mass of splenic region of pancreas" RELATED [] synonym: "calculated weight of islet beta cells in the tail region of pancreas" EXACT [] relationship: part_of CMO:0001817 ! calculated total pancreatic islet beta cell weight @@ -16099,7 +16099,7 @@ creation_date: 2013-10-11T16:27:41Z [Term] id: CMO:0001820 name: duodenal region pancreatic beta cell weight calculated as the product of pancreas duodenal region weight and corresponding beta cell fractional area -def: "A calculated measurement in which the weight, that is, the heaviness or the force with which a body is drawn toward earth by gravity, of the beta cells in the head region of the pancreas is derived by multiplying the weight of the entire head region of the pancreas by this fraction: [average cross-sectional area of pancreatic islet beta cells in the head region divided by average cross-sectional area of the head region of the pancreas]. The head region of the pancreas is the portion of the pancreas which lies closest to the duodenum, the first segment of the small intestine. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin. Area is the value representing the size of the two-dimensional extent of an object." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "A calculated measurement in which the weight, that is, the heaviness or the force with which a body is drawn toward earth by gravity, of the beta cells in the head region of the pancreas is derived by multiplying the weight of the entire head region of the pancreas by this fraction: [average cross-sectional area of pancreatic islet beta cells in the head region divided by average cross-sectional area of the head region of the pancreas]. The head region of the pancreas is the portion of the pancreas which lies closest to the duodenum, the first segment of the small intestine. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin. Area is the value representing the size of the two-dimensional extent of an object." [ISBN:978-1416049982, http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Pancreas] is_a: CMO:0001818 ! calculated weight of islet beta cells in duodenal region of pancreas created_by: JSmith creation_date: 2013-10-14T15:24:56Z @@ -16107,7 +16107,7 @@ creation_date: 2013-10-14T15:24:56Z [Term] id: CMO:0001821 name: splenic region pancreatic beta cell weight calculated as the product of pancreas splenic region weight and corresponding beta cell fractional area -def: "A calculated measurement in which the weight, that is, the heaviness or the force with which a body is drawn toward earth by gravity, of the beta cells in the tail region of the pancreas is derived by multiplying the weight of the entire tail region of the pancreas by this fraction: [average cross-sectional area of pancreatic islet beta cells in the tail region divided by average cross-sectional area of the tail region of the pancreas]. The tail region of the pancreas is the portion of the pancreas which lies furthest from the major pancreatic duct and closest to the spleen, the highly vascular lymphoid organ which serves to store blood, disintegrate old blood cells, filter foreign substances from the blood, and produce lymphocytes. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin. Area is the value representing the size of the two-dimensional extent of an object." [ISBN:978-1416049982, Multiple_Dictionaries:http\://www.thefreedictionary.com/, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "A calculated measurement in which the weight, that is, the heaviness or the force with which a body is drawn toward earth by gravity, of the beta cells in the tail region of the pancreas is derived by multiplying the weight of the entire tail region of the pancreas by this fraction: [average cross-sectional area of pancreatic islet beta cells in the tail region divided by average cross-sectional area of the tail region of the pancreas]. The tail region of the pancreas is the portion of the pancreas which lies furthest from the major pancreatic duct and closest to the spleen, the highly vascular lymphoid organ which serves to store blood, disintegrate old blood cells, filter foreign substances from the blood, and produce lymphocytes. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. A pancreatic islet is a small encapsulated region of the pancreas containing endocrine (i.e., hormone-producing) cells. An islet beta cell is a membrane-enclosed protoplasmic mass constituting the smallest structural unit of an organism that is capable of independent functioning, which is found in a pancreatic islet and produces the hormones insulin and amylin. Area is the value representing the size of the two-dimensional extent of an object." [ISBN:978-1416049982, http://www.thefreedictionary.com/, https://en.wikipedia.org/wiki/Pancreas] is_a: CMO:0001819 ! calculated weight of islet beta cells in splenic region of pancreas created_by: JSmith creation_date: 2013-10-14T15:27:30Z @@ -16290,7 +16290,7 @@ creation_date: 2013-10-16T10:37:17Z [Term] id: CMO:0001840 name: heart left ventricle end-systolic posterior wall thickness -def: "The thickness or depth (i.e. the measurement of the two-dimensional extent of the distance between the inner and outer surfaces) of the dorsal/posterior wall of the left ventricle of the heart at the end of systole, that is, when the heart muscle is maximally contracted. The dorsal wall is the portion of the muscle enclosing the ventricle which is closest to the spine and farthest from the chest wall of the organism. The left ventricle is the lower chamber of the left side of the heart, which pumps oxygenated blood out through the aorta to all the tissues of the body." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location)] +def: "The thickness or depth (i.e. the measurement of the two-dimensional extent of the distance between the inner and outer surfaces) of the dorsal/posterior wall of the left ventricle of the heart at the end of systole, that is, when the heart muscle is maximally contracted. The dorsal wall is the portion of the muscle enclosing the ventricle which is closest to the spine and farthest from the chest wall of the organism. The left ventricle is the lower chamber of the left side of the heart, which pumps oxygenated blood out through the aorta to all the tissues of the body." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Anatomical_terms_of_location)] comment: Note that "left" in this context refers to the perspective of the organism, not that of the observer. synonym: "end-systolic heart left ventricle posterior wall thickness" EXACT [] synonym: "end-systolic heart left ventricle PWT" RELATED [] @@ -16328,7 +16328,7 @@ creation_date: 2013-10-16T13:26:33Z [Term] id: CMO:0001844 name: thymus stromal cell count -def: "Measurement of the number of non-thymocyte cells, i.e., connective tissue cells such as cortical and medullary epithelial cells and dendritic cells, in the thymus. The thymus is the lymphoid organ which is the site of the proliferation, differentiation and maturation of T lymphocytes, and of the production of hormones such as thymopoietin and thymosin which control these processes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Thymus] +def: "Measurement of the number of non-thymocyte cells, i.e., connective tissue cells such as cortical and medullary epithelial cells and dendritic cells, in the thymus. The thymus is the lymphoid organ which is the site of the proliferation, differentiation and maturation of T lymphocytes, and of the production of hormones such as thymopoietin and thymosin which control these processes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Thymus] is_a: CMO:0001841 ! thymus cell count created_by: JSmith creation_date: 2013-10-16T13:44:15Z @@ -16336,7 +16336,7 @@ creation_date: 2013-10-16T13:44:15Z [Term] id: CMO:0001845 name: TCR+ thymocyte count -def: "The number of lymphocytes expressing T cell receptor molecules on their surface in a specified sample of thymus tissue. T cell receptor is a transmembrane protein complex that recognizes antigenic peptides bound to Major Histocompatibility Complex (MHC) proteins on antigen-presenting cells as part of cell-mediated immunity. The thymus is the lymphoid organ which is the site of the proliferation, differentiation and maturation of T lymphocytes, and of the production of hormones such as thymopoietin and thymosin which control these processes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.dddmag.com/content/glossary-drug-discovery-and-development-terms#t, Wikipedia:http\://en.wikipedia.org/wiki/T_cell_receptor] +def: "The number of lymphocytes expressing T cell receptor molecules on their surface in a specified sample of thymus tissue. T cell receptor is a transmembrane protein complex that recognizes antigenic peptides bound to Major Histocompatibility Complex (MHC) proteins on antigen-presenting cells as part of cell-mediated immunity. The thymus is the lymphoid organ which is the site of the proliferation, differentiation and maturation of T lymphocytes, and of the production of hormones such as thymopoietin and thymosin which control these processes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.dddmag.com/content/glossary-drug-discovery-and-development-terms#t, https://en.wikipedia.org/wiki/T_cell_receptor] synonym: "T-cell receptor positive thymic lymphocyte count" EXACT [] synonym: "T-cell receptor positive thymocyte count" EXACT [] is_a: CMO:0001843 ! thymocyte count @@ -16346,7 +16346,7 @@ creation_date: 2013-10-23T13:02:27Z [Term] id: CMO:0001846 name: CD45R+ thymocyte count -def: "The number of lymphocytes expressing the CD45 receptor (protein tyrosine phosphatase, receptor type, C; PTPRC) on their surface in a specified sample of thymus tissue. PTPRC is a transmembrane protein specifically expressed in hematopoietic cells which has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. The thymus is the lymphoid organ which is the site of the proliferation, differentiation and maturation of T lymphocytes, and of the production of hormones such as thymopoietin and thymosin which control these processes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/PTPRC] +def: "The number of lymphocytes expressing the CD45 receptor (protein tyrosine phosphatase, receptor type, C; PTPRC) on their surface in a specified sample of thymus tissue. PTPRC is a transmembrane protein specifically expressed in hematopoietic cells which has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. The thymus is the lymphoid organ which is the site of the proliferation, differentiation and maturation of T lymphocytes, and of the production of hormones such as thymopoietin and thymosin which control these processes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/PTPRC] synonym: "CD45R+ thymic lymphocyte count" EXACT [] synonym: "CD45R-positive thymocyte count" EXACT [] synonym: "leukocyte common antigen (LCA) positive thymocyte count" EXACT [] @@ -16385,7 +16385,7 @@ creation_date: 2013-10-23T13:54:39Z [Term] id: CMO:0001850 name: urine fractional sodium excretion -def: "A calculated measurement of the fraction of sodium actually excreted in the urine relative to the amount filtered by the kidneys. It is calculated as the clearance of sodium divided by the glomerular filtration rate. The standard equation for the calculation is: ((urineSodium x plasmaCreatinine)/(plasmaSodium x urineCreatinine))x100." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Fractional_sodium_excretion] +def: "A calculated measurement of the fraction of sodium actually excreted in the urine relative to the amount filtered by the kidneys. It is calculated as the clearance of sodium divided by the glomerular filtration rate. The standard equation for the calculation is: ((urineSodium x plasmaCreatinine)/(plasmaSodium x urineCreatinine))x100." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, https://en.wikipedia.org/wiki/Fractional_sodium_excretion] synonym: "urinary fractional excretion of sodium" EXACT [] is_a: CMO:0000760 ! urine sodium excretion rate is_a: CMO:0002160 ! calculated urine electrolyte excretion rate @@ -16421,7 +16421,7 @@ creation_date: 2013-11-04T17:16:16Z [Term] id: CMO:0001854 name: kidney 20-HETE level -def: "The amount of 20-hydroxyeicosatetraenoic acid, a vasoconstrictor that consists of arachidonic acid (a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14) bearing a hydroxy substituent at position 20, in a specified sample of kidney tissue, that is, tissue from one or both of the paired organs which function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Website:http\://www.nugowiki.org/index.php/20-Hydroxyeicosatetraenoic_acid] +def: "The amount of 20-hydroxyeicosatetraenoic acid, a vasoconstrictor that consists of arachidonic acid (a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14) bearing a hydroxy substituent at position 20, in a specified sample of kidney tissue, that is, tissue from one or both of the paired organs which function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, http://www.nugowiki.org/index.php/20-Hydroxyeicosatetraenoic_acid] synonym: "kidney 20-hydroxyeicosatetraenoic acid level" EXACT [] xref: CHEBI:34306 is_a: CMO:0001853 ! kidney lipid composition measurement @@ -16440,7 +16440,7 @@ creation_date: 2013-11-04T17:42:09Z [Term] id: CMO:0001856 name: pancreatic islet molecular composition measurement -def: "Any quantification of the amounts or proportions of proteins, lipids, minerals, nutrients, gases, or other substances in a specified sample of pancreatic islet tissue, i.e. one or more of the islets of Langerhans, the small, encapsulated, irregular, microscopic structures scattered throughout the pancreas and comprising its endocrine portion. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally." [ISBN:0683400088, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Stedman:Stedmans_Medical_Dictionary, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "Any quantification of the amounts or proportions of proteins, lipids, minerals, nutrients, gases, or other substances in a specified sample of pancreatic islet tissue, i.e. one or more of the islets of Langerhans, the small, encapsulated, irregular, microscopic structures scattered throughout the pancreas and comprising its endocrine portion. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally." [ISBN:0683400088, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Stedman:Stedmans_Medical_Dictionary, https://en.wikipedia.org/wiki/Pancreas] is_a: CMO:0001052 ! pancreatic islet morphological measurement is_a: CMO:0002576 ! pancreas molecular composition measurement created_by: JSmith @@ -16449,7 +16449,7 @@ creation_date: 2013-11-05T16:39:46Z [Term] id: CMO:0001857 name: pancreatic islet insulin level -def: "The amount of insulin in a specified sample of pancreatic islet tissue, i.e. one or more of the islets of Langerhans, the small, encapsulated, irregular, microscopic structures scattered throughout the pancreas and comprising its endocrine portion. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. Insulin is the fuel-regulating peptide hormone which is formed from proinsulin in the beta cells of the pancreatic islets and which promotes the storage of glucose and the uptake of amino acids, increases protein and lipid synthesis, and inhibits lipolysis and gluconeogenesis." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Pancreas] +def: "The amount of insulin in a specified sample of pancreatic islet tissue, i.e. one or more of the islets of Langerhans, the small, encapsulated, irregular, microscopic structures scattered throughout the pancreas and comprising its endocrine portion. The pancreas is the elongated, racemose gland containing both endocrine and exocrine elements which secretes hormones such as insulin and glucagon internally and digestive enzymes externally. Insulin is the fuel-regulating peptide hormone which is formed from proinsulin in the beta cells of the pancreatic islets and which promotes the storage of glucose and the uptake of amino acids, increases protein and lipid synthesis, and inhibits lipolysis and gluconeogenesis." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Pancreas] is_a: CMO:0002582 ! pancreatic islet protein/peptide composition measurement created_by: JSmith creation_date: 2013-11-05T16:59:50Z @@ -16457,7 +16457,7 @@ creation_date: 2013-11-05T16:59:50Z [Term] id: CMO:0001858 name: acute experimental autoimmune encephalomyelitis incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display acute experimental autoimmune encephalomyelitis (EAE) at a point in time or develop acute EAE within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Acute EAE is a variant of EAE having a short, monophasic timecourse of symptoms which are usually severe, followed by complete and stable recovery." [Gale:Gale_Encyclopedia_of_Medicine_2008, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "Any measurement in which the number of individuals in a study population that display acute experimental autoimmune encephalomyelitis (EAE) at a point in time or develop acute EAE within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Acute EAE is a variant of EAE having a short, monophasic timecourse of symptoms which are usually severe, followed by complete and stable recovery." [Gale:Gale_Encyclopedia_of_Medicine_2008, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "acute EAE incidence/prevalence measurement" RELATED [] synonym: "acute experimental allergic encephalomyelitis incidence/prevalence measurement" EXACT [] is_a: CMO:0001046 ! experimental autoimmune encephalomyelitis incidence/prevalence measurement @@ -16467,7 +16467,7 @@ creation_date: 2013-11-05T18:08:55Z [Term] id: CMO:0001859 name: percentage of study population developing acute experimental autoimmune encephalomyelitis during a period of time -def: "The number of new cases of acute experimental autoimmune encephalomyelitis (EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Acute EAE is a variant of EAE having a short, monophasic timecourse of symptoms which are usually severe, followed by complete and stable recovery." [Gale:Gale_Encyclopedia_of_Medicine_2008, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of new cases of acute experimental autoimmune encephalomyelitis (EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Acute EAE is a variant of EAE having a short, monophasic timecourse of symptoms which are usually severe, followed by complete and stable recovery." [Gale:Gale_Encyclopedia_of_Medicine_2008, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "acute EAE incidence" RELATED [] synonym: "acute experimental allergic encephalomyelitis incidence" RELATED [] synonym: "acute experimental autoimmune encephalomyelitis incidence" RELATED [] @@ -16481,7 +16481,7 @@ creation_date: 2013-11-05T18:15:13Z [Term] id: CMO:0001860 name: percentage of study population displaying acute experimental autoimmune encephalomyelitis at a point in time -def: "The number of individuals in a study population which display experimental autoimmune encephalomyelitis (EAE) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Acute EAE is a variant of EAE having a short, monophasic timecourse of symptoms which are usually severe, followed by complete and stable recovery." [Gale:Gale_Encyclopedia_of_Medicine_2008, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of individuals in a study population which display experimental autoimmune encephalomyelitis (EAE) at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Acute EAE is a variant of EAE having a short, monophasic timecourse of symptoms which are usually severe, followed by complete and stable recovery." [Gale:Gale_Encyclopedia_of_Medicine_2008, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] synonym: "acute EAE prevalence" RELATED [] synonym: "acute experimental allergic encephalomyelitis prevalence" RELATED [] synonym: "acute experimental autoimmune encephalomyelitis prevalence" RELATED [] @@ -16503,7 +16503,7 @@ creation_date: 2013-11-05T18:53:03Z [Term] id: CMO:0001862 name: antibody titer -def: "Measurement of the amount of a specific antibody determined as the maximal dilution of the antibody solution at which that antibody can still be detected. The value represents the denominator of the dilution ratio, i.e., a titer of 32 means that the sample can be maximally diluted 1/32 and still contain enough antibody to be detected. An antibody is an immunoglobulin molecule possessing a specific amino acid sequence that binds to a specific antigen, a substance introduced into an organism which initiates an immune response including the production of the very antibodies which bind to it in an effort to destroy it." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Antibody_titer] +def: "Measurement of the amount of a specific antibody determined as the maximal dilution of the antibody solution at which that antibody can still be detected. The value represents the denominator of the dilution ratio, i.e., a titer of 32 means that the sample can be maximally diluted 1/32 and still contain enough antibody to be detected. An antibody is an immunoglobulin molecule possessing a specific amino acid sequence that binds to a specific antigen, a substance introduced into an organism which initiates an immune response including the production of the very antibodies which bind to it in an effort to destroy it." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Antibody_titer] is_a: CMO:0001861 ! antibody measurement created_by: JSmith creation_date: 2013-11-05T19:04:58Z @@ -16511,7 +16511,7 @@ creation_date: 2013-11-05T19:04:58Z [Term] id: CMO:0001863 name: autoantibody titer -def: "Measurement of the amount of a specific autoantibody determined as the maximal dilution of the autoantibody solution at which that antibody can still be detected. The value represents the denominator of the dilution ratio, i.e., a titer of 32 means that the sample can be maximally diluted 1/32 and still contain enough antibody to be detected. An antibody is an immunoglobulin molecule possessing a specific amino acid sequence that binds to a specific antigen, a substance introduced into an organism which initiates an immune response including the production of the very antibodies which bind to it in an effort to destroy it. An autoantibody is an antibody that attacks the cells, tissues, native proteins, or other endogenous molecules of the organism in which it was formed." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Antibody_titer] +def: "Measurement of the amount of a specific autoantibody determined as the maximal dilution of the autoantibody solution at which that antibody can still be detected. The value represents the denominator of the dilution ratio, i.e., a titer of 32 means that the sample can be maximally diluted 1/32 and still contain enough antibody to be detected. An antibody is an immunoglobulin molecule possessing a specific amino acid sequence that binds to a specific antigen, a substance introduced into an organism which initiates an immune response including the production of the very antibodies which bind to it in an effort to destroy it. An autoantibody is an antibody that attacks the cells, tissues, native proteins, or other endogenous molecules of the organism in which it was formed." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Antibody_titer] synonym: "anti-self antibody titer" EXACT [] is_a: CMO:0001862 ! antibody titer is_a: CMO:0002614 ! autoantibody level @@ -16583,7 +16583,7 @@ creation_date: 2013-11-07T17:41:02Z [Term] id: CMO:0001871 name: head and neck tumor measurement -def: "Any value resulting from the quantification of a morphological or physiological parameter related to tumors of the head and neck, a group of biologically similar cancers that start in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, and/or larynx. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Head_and_neck_cancer] +def: "Any value resulting from the quantification of a morphological or physiological parameter related to tumors of the head and neck, a group of biologically similar cancers that start in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, and/or larynx. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Head_and_neck_cancer] comment: Note that "tumors of the head and neck" or "cancers of the head and neck" refers to a specific group of neoplasms, not just to any tumor located anywhere in the head or neck of an individual. According to the National Cancer Institute "Cancers of the brain, the eye, the esophagus, and the thyroid gland, as well as those of the scalp, skin, muscles, and bones of the head and neck, are not usually classified as head and neck cancers". synonym: "Not4Curation" RELATED [] xref: MESH:D006258 @@ -16594,7 +16594,7 @@ creation_date: 2013-11-08T11:45:08Z [Term] id: CMO:0001872 name: squamous cell carcinoma of the head and neck measurement -def: "Any value resulting from the quantification of a morphological or physiological parameter related to tumors arising in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, and/or larynx, from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Head_and_neck_cancer, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "Any value resulting from the quantification of a morphological or physiological parameter related to tumors arising in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, and/or larynx, from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Head_and_neck_cancer, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] comment: Note that "tumors of the head and neck" or "cancers of the head and neck" refers to a specific group of neoplasms, not just to any tumor located anywhere in the head or neck of an individual. According to the National Cancer Institute "Cancers of the brain, the eye, the esophagus, and the thyroid gland, as well as those of the scalp, skin, muscles, and bones of the head and neck, are not usually classified as head and neck cancers". synonym: "Not4Curation" RELATED [] synonym: "SCCHN measurement" RELATED [] @@ -16608,7 +16608,7 @@ creation_date: 2013-11-08T11:52:17Z [Term] id: CMO:0001873 name: squamous cell carcinoma of the tongue measurement -def: "Any value resulting from the quantification of a morphological or physiological parameter related to tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "Any value resulting from the quantification of a morphological or physiological parameter related to tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] synonym: "Not4Curation" RELATED [] xref: MESH:D002294 xref: MESH:D014062 @@ -16620,7 +16620,7 @@ creation_date: 2013-11-08T12:06:29Z [Term] id: CMO:0001874 name: squamous cell carcinoma of the tongue tumor diameter -def: "The length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single tumor or an area occupied by tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "The length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single tumor or an area occupied by tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] synonym: "diameter of squamous cell tumors of the tongue" EXACT [] synonym: "tongue SCC tumor diameter" RELATED [] xref: MESH:D002294 @@ -16633,7 +16633,7 @@ creation_date: 2013-11-08T12:10:04Z [Term] id: CMO:0001875 name: squamous cell carcinoma of the tongue maximum tumor diameter -def: "The largest value in a collection in which each value corresponds to the length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single squamous cell tumor of the tongue. A squamous cell carcinoma of the tongue is a tumor arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "The largest value in a collection in which each value corresponds to the length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single squamous cell tumor of the tongue. A squamous cell carcinoma of the tongue is a tumor arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] synonym: "DTCmax" RELATED [] synonym: "maximum diameter of squamous cell tumors of the tongue" EXACT [] synonym: "tongue SCC maximum tumor diameter" RELATED [] @@ -16646,7 +16646,7 @@ creation_date: 2013-11-08T12:14:37Z [Term] id: CMO:0001876 name: squamous cell carcinoma of the head and neck tumor number -def: "A value or quantity determined by count of tumors arising in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, and/or larynx, from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Head_and_neck_cancer, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "A value or quantity determined by count of tumors arising in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, and/or larynx, from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Head_and_neck_cancer, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] comment: Note that "tumors of the head and neck" or "cancers of the head and neck" refers to a specific group of neoplasms, not just to any tumor located anywhere in the head or neck of an individual. According to the National Cancer Institute "Cancers of the brain, the eye, the esophagus, and the thyroid gland, as well as those of the scalp, skin, muscles, and bones of the head and neck, are not usually classified as head and neck cancers". synonym: "number of squamous cell tumors of the head and neck" EXACT [] synonym: "SSCHN tumor number" RELATED [] @@ -16659,7 +16659,7 @@ creation_date: 2013-11-08T12:16:41Z [Term] id: CMO:0001877 name: non-tongue squamous cell carcinoma of the head and neck tumor number -def: "A value or quantity determined by count of tumors arising in the lip, nasal cavity, paranasal sinuses, pharynx, larynx, and/or in the oral cavity excluding the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Head_and_neck_cancer, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "A value or quantity determined by count of tumors arising in the lip, nasal cavity, paranasal sinuses, pharynx, larynx, and/or in the oral cavity excluding the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Head_and_neck_cancer, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] comment: Note that "tumors of the head and neck" or "cancers of the head and neck" refers to a specific group of neoplasms, not just to any tumor located anywhere in the head or neck of an individual. According to the National Cancer Institute "Cancers of the brain, the eye, the esophagus, and the thyroid gland, as well as those of the scalp, skin, muscles, and bones of the head and neck, are not usually classified as head and neck cancers". synonym: "non-tongue SCCHN tumor number" RELATED [] synonym: "number of non-tongue squamous cell tumors of the head and neck" EXACT [] @@ -16672,7 +16672,7 @@ creation_date: 2013-11-08T12:21:25Z [Term] id: CMO:0001878 name: squamous cell carcinoma of the tongue tumor number -def: "A value or quantity determined by count of tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "A value or quantity determined by count of tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] synonym: "number of squamous cell tumors of the tongue" EXACT [] synonym: "tongue SCC tumor number" RELATED [] xref: MESH:D002294 @@ -16686,7 +16686,7 @@ creation_date: 2013-11-08T12:24:06Z [Term] id: CMO:0001879 name: number of squamous cell tumors of the tongue with diameter greater than 5 mm -def: "A value or quantity determined by count of squamous cell carcinoma tumors of the tongue in which the diameter, the length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single tumor, measures at least 5 millimeters (5/1000ths of a meter). Squamous cell carcinoma of the tongue is comprised of tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "A value or quantity determined by count of squamous cell carcinoma tumors of the tongue in which the diameter, the length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single tumor, measures at least 5 millimeters (5/1000ths of a meter). Squamous cell carcinoma of the tongue is comprised of tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] synonym: "squamous cell carcinoma of the tongue number of tumors with diameter greater than 5 mm" EXACT [] synonym: "tongue SCC number of tumors with diameter greater than 5 mm" RELATED [] xref: MESH:D002294 @@ -16716,7 +16716,7 @@ creation_date: 2013-11-08T15:42:56Z [Term] id: CMO:0001882 name: absolute change in pulse pressure -def: "The difference in the pulse pressure of an individual between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. Pulse pressure is the difference between systolic and diastolic blood pressures, i.e. the difference between the maximal arterial pressure and minimal arterial pressure during the cardiac cycle." [Berne_and_Levy:Berne_and_Levy_Physiology--6th_Ed, Collins:Collins_Online_English_Dictionary, ISBN:978-0323073622, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in the pulse pressure of an individual between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. Pulse pressure is the difference between systolic and diastolic blood pressures, i.e. the difference between the maximal arterial pressure and minimal arterial pressure during the cardiac cycle." [Berne_and_Levy:Berne_and_Levy_Physiology--6th_Ed, Collins:Collins_Online_English_Dictionary, ISBN:978-0323073622, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0000292 ! pulse pressure created_by: JSmith @@ -16725,7 +16725,7 @@ creation_date: 2013-11-08T16:00:08Z [Term] id: CMO:0001883 name: stomach measurement -def: "Any value resulting from the quantification of a morphological or physiological parameter of the stomach, the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "Any value resulting from the quantification of a morphological or physiological parameter of the stomach, the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric measurement" EXACT [] synonym: "Not4Curation" RELATED [] is_a: CMO:0000669 ! organ measurement @@ -16736,7 +16736,7 @@ creation_date: 2013-11-08T17:49:10Z [Term] id: CMO:0001884 name: stomach lesion measurement -def: "Measurement of any lesion in the stomach. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "Measurement of any lesion in the stomach. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric lesion measurement" EXACT [] synonym: "Not4Curation" RELATED [] is_a: CMO:0000677 ! organ lesion measurement @@ -16747,7 +16747,7 @@ creation_date: 2013-11-08T17:54:09Z [Term] id: CMO:0001885 name: stomach tumorous lesion measurement -def: "Measurement of an organ lesion which is or has the potential to become a tumor, that is, a neoplasm or new growth of tissue in which cell multiplication is more or less uncontrolled and progressive. Tumorous lesions include tumors, preneoplastic lesions, and hyperplastic lesions composed of histologically normal cells. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "Measurement of an organ lesion which is or has the potential to become a tumor, that is, a neoplasm or new growth of tissue in which cell multiplication is more or less uncontrolled and progressive. Tumorous lesions include tumors, preneoplastic lesions, and hyperplastic lesions composed of histologically normal cells. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric tumorous lesion measurement" EXACT [] synonym: "Not4Curation" RELATED [] is_a: CMO:0000859 ! organ tumorous lesion measurement @@ -16758,7 +16758,7 @@ creation_date: 2013-11-08T17:56:57Z [Term] id: CMO:0001886 name: stomach non-tumorous lesion measurement -def: "Measurement of a stomach lesion which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "Measurement of a stomach lesion which is not neoplastic in origin. A lesion is a localized pathological change in structure of an organ or tissue due to injury or disease; especially one that is circumscribed and well defined. Examples of non-tumorous lesions would include wounds, sores, ulcers, infarctions, etc. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric non-tumorous lesion measurement" EXACT [] synonym: "Not4Curation" RELATED [] is_a: CMO:0000860 ! organ non-tumorous lesion measurement @@ -16769,7 +16769,7 @@ creation_date: 2013-11-08T17:57:00Z [Term] id: CMO:0001887 name: stomach tumor measurement -def: "Any value resulting from the quantification of a morphological or physiological parameter of a stomach tumor. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "Any value resulting from the quantification of a morphological or physiological parameter of a stomach tumor. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric tumor measurement" EXACT [] synonym: "Not4Curation" RELATED [] is_a: CMO:0000341 ! tumor measurement @@ -16780,7 +16780,7 @@ creation_date: 2013-11-08T18:02:06Z [Term] id: CMO:0001888 name: stomach tumor depth of invasion -def: "Measurement of the distance a stomach tumor has penetrated into or through the adjoining tissue. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "Measurement of the distance a stomach tumor has penetrated into or through the adjoining tissue. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric tumor depth of invasion" EXACT [] is_a: CMO:0001887 ! stomach tumor measurement created_by: JSmith @@ -16789,7 +16789,7 @@ creation_date: 2013-11-08T18:04:27Z [Term] id: CMO:0001889 name: stomach tumor diameter -def: "The length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single tumor or an area occupied by tumors of the stomach. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "The length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single tumor or an area occupied by tumors of the stomach. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric tumor diameter" EXACT [] is_a: CMO:0001887 ! stomach tumor measurement created_by: JSmith @@ -16798,7 +16798,7 @@ creation_date: 2013-11-08T18:05:26Z [Term] id: CMO:0001890 name: stomach tumor number -def: "A quantification of tumors on or in the stomach or a specified sample of stomach tissue, as determined by count. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "A quantification of tumors on or in the stomach or a specified sample of stomach tissue, as determined by count. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The stomach is the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric tumor number" EXACT [] synonym: "stomach tumor count" EXACT [] is_a: CMO:0001887 ! stomach tumor measurement @@ -16808,7 +16808,7 @@ creation_date: 2013-11-08T18:06:52Z [Term] id: CMO:0001891 name: chronic experimental autoimmune encephalomyelitis incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display chronic experimental autoimmune encephalomyelitis (EAE) at a point in time or develop chronic EAE within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Chronic EAE is a variant of EAE characterized by a long duration and slow, constant progression." [Gale:Gale_Encyclopedia_of_Medicine_2008, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "Any measurement in which the number of individuals in a study population that display chronic experimental autoimmune encephalomyelitis (EAE) at a point in time or develop chronic EAE within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Chronic EAE is a variant of EAE characterized by a long duration and slow, constant progression." [Gale:Gale_Encyclopedia_of_Medicine_2008, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] comment: For disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement, use the term for relapsing-remitting experimental autoimmune encephalomyelitis. synonym: "chronic EAE incidence/prevalence measurement" RELATED [] is_a: CMO:0001046 ! experimental autoimmune encephalomyelitis incidence/prevalence measurement @@ -16818,7 +16818,7 @@ creation_date: 2013-11-18T12:55:36Z [Term] id: CMO:0001892 name: percentage of study population displaying chronic experimental autoimmune encephalomyelitis at a point in time -def: "A measurement in which the number of individuals in a study population that display, i.e., are manifesting symptoms of or have been diagnosed with, chronic experimental autoimmune encephalomyelitis (EAE) at a point in time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Chronic EAE is a variant of EAE characterized by a long duration and slow, constant progression." [Gale:Gale_Encyclopedia_of_Medicine_2008, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "A measurement in which the number of individuals in a study population that display, i.e., are manifesting symptoms of or have been diagnosed with, chronic experimental autoimmune encephalomyelitis (EAE) at a point in time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Chronic EAE is a variant of EAE characterized by a long duration and slow, constant progression." [Gale:Gale_Encyclopedia_of_Medicine_2008, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] comment: For disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement, use the term for relapsing-remitting experimental autoimmune encephalomyelitis. synonym: "chronic EAE prevalence" RELATED [] synonym: "percentage of study population displaying chronic EAE at a point in time" RELATED [] @@ -16830,7 +16830,7 @@ creation_date: 2013-11-18T13:23:49Z [Term] id: CMO:0001893 name: percentage of study population developing chronic experimental autoimmune encephalomyelitis during a period of time -def: "The number of new cases of chronic experimental autoimmune encephalomyelitis (EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Chronic EAE is a variant of EAE characterized by a long duration and slow, constant progression." [Gale:Gale_Encyclopedia_of_Medicine_2008, Wikipedia:http\://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] +def: "The number of new cases of chronic experimental autoimmune encephalomyelitis (EAE) appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage. EAE is an animal model of brain inflammation in which inflammation is induced through immunization of the animal with central nervous system antigens or by the passive transfer of autoreactive T cells. Chronic EAE is a variant of EAE characterized by a long duration and slow, constant progression." [Gale:Gale_Encyclopedia_of_Medicine_2008, https://en.wikipedia.org/wiki/Experimental_autoimmune_encephalomyelitis] comment: For disease characterized by repeated symptomatic attacks followed by complete or almost complete improvement, use the term for relapsing-remitting experimental autoimmune encephalomyelitis. synonym: "chronic EAE incidence" RELATED [] synonym: "percentage of study population developing chronic EAE during a period of time" RELATED [] @@ -16867,7 +16867,7 @@ creation_date: 2013-11-18T15:57:27Z [Term] id: CMO:0001897 name: ratio of change in renal blood flow rate to kidney weight -def: "A calculated measurement in which the difference in the volume of blood delivered to and/or exiting from the kidneys per unit time between two points in time or two conditions is divided by the weight (heaviness or degree to which a body is drawn toward the earth by gravity) of one or both kidneys, and presented as a ratio, fraction, quotient or percentage. The kidney is the paired organ which functions to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "A calculated measurement in which the difference in the volume of blood delivered to and/or exiting from the kidneys per unit time between two points in time or two conditions is divided by the weight (heaviness or degree to which a body is drawn toward the earth by gravity) of one or both kidneys, and presented as a ratio, fraction, quotient or percentage. The kidney is the paired organ which functions to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Renal_blood_flow] is_a: CMO:0001167 ! calculated renal blood flow rate created_by: JSmith creation_date: 2013-11-18T16:20:39Z @@ -16894,7 +16894,7 @@ creation_date: 2013-11-18T17:23:40Z [Term] id: CMO:0001900 name: absolute change in renal vascular resistance -def: "The difference in renal vascular resistance between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. Renal vascular resistance is the degree to which the blood vessels of the kidneys impede the flow of blood through them. Blood vessels are the network of muscular tubes that carry blood throughout the body. Blood is the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Kidney is the paired organ which functions to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in renal vascular resistance between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. Renal vascular resistance is the degree to which the blood vessels of the kidneys impede the flow of blood through them. Blood vessels are the network of muscular tubes that carry blood throughout the body. Blood is the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Kidney is the paired organ which functions to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Collins:Collins_Online_English_Dictionary, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in kidney vascular resistance" EXACT [] is_a: CMO:0001899 ! calculated renal vascular resistance @@ -16904,7 +16904,7 @@ creation_date: 2013-11-18T17:26:57Z [Term] id: CMO:0001901 name: slope of contraction-induced renal vascular resistance curve -def: "A calculated measurement of the slope, the ratio of vertical change to horizontal change, of the line of a graph designating the change in renal vascular resistance in response to a drug or other condition which causes constriction or reduction of the interior diameter of blood vessels. Renal vascular resistance is the degree to which the blood vessels of the kidneys impede the flow of blood through them. Blood vessels are the network of muscular tubes that carry blood throughout the body. Blood is the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Kidney is the paired organ which functions to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Website:http\://www.mathnstuff.com/math/spoken/here/1words/s/s22.htm] +def: "A calculated measurement of the slope, the ratio of vertical change to horizontal change, of the line of a graph designating the change in renal vascular resistance in response to a drug or other condition which causes constriction or reduction of the interior diameter of blood vessels. Renal vascular resistance is the degree to which the blood vessels of the kidneys impede the flow of blood through them. Blood vessels are the network of muscular tubes that carry blood throughout the body. Blood is the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Kidney is the paired organ which functions to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, http://www.mathnstuff.com/math/spoken/here/1words/s/s22.htm] synonym: "slope of constriction-induced renal vascular resistance curve" EXACT [] synonym: "slope of contraction-induced kidney vascular resistance curve" EXACT [] is_a: CMO:0001899 ! calculated renal vascular resistance @@ -17018,7 +17018,7 @@ creation_date: 2013-11-19T13:00:18Z [Term] id: CMO:0001914 name: renal plasma flow -def: "The amount of plasma that perfuses the kidneys per unit time. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. The kidneys are the paired organs that function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "The amount of plasma that perfuses the kidneys per unit time. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. The kidneys are the paired organs that function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Renal_blood_flow] synonym: "renal plasma flow rate" EXACT [] synonym: "RPF" RELATED [] is_a: CMO:0000906 ! kidney measurement @@ -17028,7 +17028,7 @@ creation_date: 2013-11-19T14:28:34Z [Term] id: CMO:0001915 name: ratio of the effective renal plasma flow to the weight of both kidneys -def: "A calculated measurement in which the effective renal plasma flow rate (eRPF) is divided by weight (i.e. the heaviness or the degree to which an object is drawn toward the earth by gravity) of both kidneys and presented as a ratio, fraction, quotient or percentage. The eRPF is the amount of plasma that perfuses the renal tubules per unit time, derived by measurement of the clearance rate of a non-metabolizable solute such as para-aminohippurate (PAH). Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. The kidneys are the paired organs that function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "A calculated measurement in which the effective renal plasma flow rate (eRPF) is divided by weight (i.e. the heaviness or the degree to which an object is drawn toward the earth by gravity) of both kidneys and presented as a ratio, fraction, quotient or percentage. The eRPF is the amount of plasma that perfuses the renal tubules per unit time, derived by measurement of the clearance rate of a non-metabolizable solute such as para-aminohippurate (PAH). Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. The kidneys are the paired organs that function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Renal_blood_flow] synonym: "effective renal plasma flow rate to both kidney weight ratio" EXACT [] synonym: "eRPF to both kidney weight ratio" RELATED [] is_a: CMO:0001916 ! effective renal plasma flow @@ -17038,7 +17038,7 @@ creation_date: 2013-11-19T14:51:51Z [Term] id: CMO:0001916 name: effective renal plasma flow -def: "A calculated measurement of the amount of plasma that perfuses the renal tubules per unit time, derived by measurement of the clearance rate of a non-metabolizable solute such as para-aminohippurate (PAH). The effective RPF is approximately 10% less than the actual RPF. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. The kidneys are the paired organs that function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "A calculated measurement of the amount of plasma that perfuses the renal tubules per unit time, derived by measurement of the clearance rate of a non-metabolizable solute such as para-aminohippurate (PAH). The effective RPF is approximately 10% less than the actual RPF. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. The kidneys are the paired organs that function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Renal_blood_flow] synonym: "effective renal plasma flow rate" EXACT [] synonym: "eRPF" RELATED [] is_a: CMO:0001917 ! calculated renal plasma flow @@ -17048,7 +17048,7 @@ creation_date: 2013-11-19T14:52:06Z [Term] id: CMO:0001917 name: calculated renal plasma flow -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of plasma that perfuses the kidneys per unit time. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. The kidneys are the paired organs that function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of plasma that perfuses the kidneys per unit time. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. The kidneys are the paired organs that function to maintain proper water and electrolyte balance, regulate acid-base concentration, and filter the blood of metabolic wastes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Renal_blood_flow] synonym: "calculated renal plasma flow rate" EXACT [] synonym: "calculated RPF" RELATED [] is_a: CMO:0001914 ! renal plasma flow @@ -17085,7 +17085,7 @@ creation_date: 2013-11-22T16:11:04Z [Term] id: CMO:0001921 name: liver gamma-glutamyltranspeptidase mRNA level -def: "Measurement of the amount of messenger ribonucleic acids (mRNA) which specifically codes for the amino acid sequence of the enzyme gamma-glutamyltranspeptidase (GGT) in a specified sample of liver. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water, and plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification." [Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase] +def: "Measurement of the amount of messenger ribonucleic acids (mRNA) which specifically codes for the amino acid sequence of the enzyme gamma-glutamyltranspeptidase (GGT) in a specified sample of liver. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water, and plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification." [Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase] synonym: "liver GGTP mRNA level" RELATED [] is_a: CMO:0001919 ! liver ribonucleic acid composition measurement created_by: JSmith @@ -17094,7 +17094,7 @@ creation_date: 2013-11-22T16:12:03Z [Term] id: CMO:0001922 name: liver O-6-methylguanine-DNA methyltransferase mRNA level -def: "Measurement of the amount of messenger ribonucleic acids (mRNA) which specifically codes for the amino acid sequence of the enzyme O-6-methylguanine-DNA methyltransferase (MGMT) in a specified sample of liver. MGMT is an enzyme that repairs the naturally occurring mutagenic DNA lesion O6-methylguanine back to guanine to prevent mismatch and error during DNA replication and transcription." [Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/O-6-methylguanine-DNA_methyltransferase] +def: "Measurement of the amount of messenger ribonucleic acids (mRNA) which specifically codes for the amino acid sequence of the enzyme O-6-methylguanine-DNA methyltransferase (MGMT) in a specified sample of liver. MGMT is an enzyme that repairs the naturally occurring mutagenic DNA lesion O6-methylguanine back to guanine to prevent mismatch and error during DNA replication and transcription." [Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/O-6-methylguanine-DNA_methyltransferase] synonym: "liver MGMT mRNA level" RELATED [] is_a: CMO:0001919 ! liver ribonucleic acid composition measurement created_by: JSmith @@ -17103,7 +17103,7 @@ creation_date: 2013-11-22T16:12:06Z [Term] id: CMO:0001923 name: blood acute phase protein measurement -def: "Any measurement related to a morphological or physiological parameter, such as the amount or composition, of acute phase proteins in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Acute phase proteins comprise a class of proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Acute_phase_protein] +def: "Any measurement related to a morphological or physiological parameter, such as the amount or composition, of acute phase proteins in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Acute phase proteins comprise a class of proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Acute_phase_protein] is_a: CMO:0000028 ! blood protein measurement created_by: JSmith creation_date: 2013-11-26T11:03:57Z @@ -17127,7 +17127,7 @@ creation_date: 2013-11-26T11:06:54Z [Term] id: CMO:0001926 name: blood interleukin-6 level -def: "Measurement of the amount of interleukin-6 (IL6) in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. IL6 is an interleukin that acts as both a pro-inflammatory and an anti-inflammatory cytokine with functions in inflammation and the maturation of B cells." [RGD:1352582, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Interleukin_6] +def: "Measurement of the amount of interleukin-6 (IL6) in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. IL6 is an interleukin that acts as both a pro-inflammatory and an anti-inflammatory cytokine with functions in inflammation and the maturation of B cells." [RGD:1352582, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Interleukin_6] synonym: "blood IL6 level" RELATED [] is_a: CMO:0001923 ! blood acute phase protein measurement is_a: CMO:0001925 ! blood interleukin measurement @@ -17137,7 +17137,7 @@ creation_date: 2013-11-26T11:14:04Z [Term] id: CMO:0001927 name: plasma interleukin-6 level -def: "Measurement of the amount of interleukin-6 (IL6) in plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. IL6 is an interleukin that acts as both a pro-inflammatory and an anti-inflammatory cytokine with functions in inflammation and the maturation of B cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, RGD:1352582, Wikipedia:http\://en.wikipedia.org/wiki/Interleukin_6] +def: "Measurement of the amount of interleukin-6 (IL6) in plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. IL6 is an interleukin that acts as both a pro-inflammatory and an anti-inflammatory cytokine with functions in inflammation and the maturation of B cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, RGD:1352582, https://en.wikipedia.org/wiki/Interleukin_6] synonym: "plasma IL6 level" RELATED [] is_a: CMO:0001926 ! blood interleukin-6 level created_by: JSmith @@ -17146,7 +17146,7 @@ creation_date: 2013-11-26T11:16:08Z [Term] id: CMO:0001928 name: serum interleukin-6 level -def: "Measurement of the amount of interleukin-6 (IL6) in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. IL6 is an interleukin that acts as both a pro-inflammatory and an anti-inflammatory cytokine with functions in inflammation and the maturation of B cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, RGD:1352582, Wikipedia:http\://en.wikipedia.org/wiki/Interleukin_6] +def: "Measurement of the amount of interleukin-6 (IL6) in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. IL6 is an interleukin that acts as both a pro-inflammatory and an anti-inflammatory cytokine with functions in inflammation and the maturation of B cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, RGD:1352582, https://en.wikipedia.org/wiki/Interleukin_6] synonym: "serum IL6 level" RELATED [] is_a: CMO:0001926 ! blood interleukin-6 level created_by: JSmith @@ -17217,7 +17217,7 @@ creation_date: 2013-11-26T13:11:46Z [Term] id: CMO:0001936 name: brain phytosterol level -def: "The amount of phytosterol(s) in a specified sample of brain. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [Wikipedia:http\://en.wikipedia.org/wiki/Phytosterol] +def: "The amount of phytosterol(s) in a specified sample of brain. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [https://en.wikipedia.org/wiki/Phytosterol] synonym: "brain plant sterol and stanol level" RELATED [] xref: CHEBI:26125 is_a: CMO:0001934 ! brain sterol level @@ -17227,7 +17227,7 @@ creation_date: 2013-11-26T13:50:07Z [Term] id: CMO:0001937 name: brain campesterol level -def: "The amount of campesterol, a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol, in a specified sample of brain." [Wikipedia:http\://en.wikipedia.org/wiki/Campesterol] +def: "The amount of campesterol, a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol, in a specified sample of brain." [https://en.wikipedia.org/wiki/Campesterol] xref: CHEBI:28623 is_a: CMO:0001936 ! brain phytosterol level created_by: JSmith @@ -17236,7 +17236,7 @@ creation_date: 2013-11-26T13:59:22Z [Term] id: CMO:0001938 name: brain sitosterol level -def: "The amount of sitosterol, a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol, in a specified sample of brain." [Wikipedia:http\://en.wikipedia.org/wiki/Sitosterol] +def: "The amount of sitosterol, a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol, in a specified sample of brain." [https://en.wikipedia.org/wiki/Sitosterol] synonym: "brain beta-sitosterol level" NARROW [] xref: CHEBI:27693 is_a: CMO:0001936 ! brain phytosterol level @@ -17254,7 +17254,7 @@ creation_date: 2013-11-26T14:14:38Z [Term] id: CMO:0001940 name: liver sitosterol level -def: "The amount of sitosterol, a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol, in a specified sample of liver." [Wikipedia:http\://en.wikipedia.org/wiki/Sitosterol] +def: "The amount of sitosterol, a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol, in a specified sample of liver." [https://en.wikipedia.org/wiki/Sitosterol] synonym: "liver beta-sitosterol level" NARROW [] xref: CHEBI:27693 is_a: CMO:0001942 ! liver phytosterol level @@ -17264,7 +17264,7 @@ creation_date: 2013-11-26T14:18:02Z [Term] id: CMO:0001941 name: liver campesterol level -def: "The amount of campesterol, a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol, in a specified sample of liver." [Wikipedia:http\://en.wikipedia.org/wiki/Campesterol] +def: "The amount of campesterol, a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol, in a specified sample of liver." [https://en.wikipedia.org/wiki/Campesterol] xref: CHEBI:28623 is_a: CMO:0001942 ! liver phytosterol level created_by: JSmith @@ -17273,7 +17273,7 @@ creation_date: 2013-11-26T14:18:02Z [Term] id: CMO:0001942 name: liver phytosterol level -def: "The amount of phytosterol(s) in a specified sample of liver. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [Wikipedia:http\://en.wikipedia.org/wiki/Phytosterol] +def: "The amount of phytosterol(s) in a specified sample of liver. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [https://en.wikipedia.org/wiki/Phytosterol] synonym: "liver plant sterol and stanol level" RELATED [] xref: CHEBI:26125 is_a: CMO:0001939 ! liver sterol level @@ -17283,7 +17283,7 @@ creation_date: 2013-11-26T14:18:02Z [Term] id: CMO:0001943 name: plasma sitosterol level -def: "The amount of sitosterol, a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol, in a specified sample of plasma." [Wikipedia:http\://en.wikipedia.org/wiki/Sitosterol] +def: "The amount of sitosterol, a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol, in a specified sample of plasma." [https://en.wikipedia.org/wiki/Sitosterol] synonym: "plasma beta-sitosterol level" NARROW [] xref: CHEBI:27693 is_a: CMO:0001945 ! plasma phytosterol level @@ -17293,7 +17293,7 @@ creation_date: 2013-11-26T14:30:32Z [Term] id: CMO:0001944 name: plasma campesterol level -def: "The amount of campesterol, a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol, in a specified sample of plasma." [Wikipedia:http\://en.wikipedia.org/wiki/Campesterol] +def: "The amount of campesterol, a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol, in a specified sample of plasma." [https://en.wikipedia.org/wiki/Campesterol] xref: CHEBI:28623 is_a: CMO:0001945 ! plasma phytosterol level created_by: JSmith @@ -17302,7 +17302,7 @@ creation_date: 2013-11-26T14:30:32Z [Term] id: CMO:0001945 name: plasma phytosterol level -def: "The amount of phytosterol(s) in a specified sample of plasma. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [Wikipedia:http\://en.wikipedia.org/wiki/Phytosterol] +def: "The amount of phytosterol(s) in a specified sample of plasma. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [https://en.wikipedia.org/wiki/Phytosterol] synonym: "plasma plant sterol and stanol level" RELATED [] xref: CHEBI:26125 is_a: CMO:0002050 ! plasma sterol level @@ -17351,7 +17351,7 @@ creation_date: 2013-11-26T15:17:34Z [Term] id: CMO:0001950 name: number of squamous cell tumors of the tongue with diameter greater than 3 mm -def: "A value or quantity determined by count of squamous cell carcinoma tumors of the tongue in which the diameter, the length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single tumor, measures at least 3 millimeters (3/1000ths of a meter). Squamous cell carcinoma of the tongue is comprised of tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "A value or quantity determined by count of squamous cell carcinoma tumors of the tongue in which the diameter, the length of a straight line passing through the center and connecting opposite points on the circumference of a circle circumscribing a single tumor, measures at least 3 millimeters (3/1000ths of a meter). Squamous cell carcinoma of the tongue is comprised of tumors arising in the tongue from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function. The tongue is the movable muscular organ on the floor of the mouth; it is the chief organ of taste, and aids in mastication, swallowing, and speech." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] synonym: "squamous cell carcinoma of the tongue number of tumors with diameter greater than 3 mm" EXACT [] synonym: "tongue SCC number of tumors with diameter greater than 3 mm" RELATED [] xref: MESH:D002294 @@ -17399,7 +17399,7 @@ creation_date: 2013-11-26T15:48:07Z [Term] id: CMO:0001955 name: renal blood flow rate to kidney weight ratio -def: "A calculated measurement in which the value for the volume of blood delivered to and/or exiting from the kidneys per unit time is divided by the weight (heaviness or degree to which an object is drawn toward the earth by gravity) of one or both kidneys, and presented as a ratio, fraction, quotient or percentage." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Renal_blood_flow] +def: "A calculated measurement in which the value for the volume of blood delivered to and/or exiting from the kidneys per unit time is divided by the weight (heaviness or degree to which an object is drawn toward the earth by gravity) of one or both kidneys, and presented as a ratio, fraction, quotient or percentage." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Renal_blood_flow] is_a: CMO:0001167 ! calculated renal blood flow rate created_by: JSmith creation_date: 2013-11-26T16:04:13Z @@ -17407,7 +17407,7 @@ creation_date: 2013-11-26T16:04:13Z [Term] id: CMO:0001956 name: blood cartilage oligomeric matrix protein level -def: "The amount of cartilage oligomeric matrix protein (COMP), a noncollagenous extracellular matrix protein that serves as a marker of cartilage turnover, in a specified sample of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [RGD:736605, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Cartilage_oligomeric_matrix_protein] +def: "The amount of cartilage oligomeric matrix protein (COMP), a noncollagenous extracellular matrix protein that serves as a marker of cartilage turnover, in a specified sample of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [RGD:736605, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Cartilage_oligomeric_matrix_protein] synonym: "blood COMP level" RELATED [] is_a: CMO:0000028 ! blood protein measurement created_by: JSmith @@ -17416,7 +17416,7 @@ creation_date: 2013-11-27T15:03:48Z [Term] id: CMO:0001957 name: serum cartilage oligomeric matrix protein level -def: "The amount of cartilage oligomeric matrix protein (COMP), a noncollagenous extracellular matrix protein that serves as a marker of cartilage turnover, in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, RGD:736605, Wikipedia:http\://en.wikipedia.org/wiki/Cartilage_oligomeric_matrix_protein] +def: "The amount of cartilage oligomeric matrix protein (COMP), a noncollagenous extracellular matrix protein that serves as a marker of cartilage turnover, in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, RGD:736605, https://en.wikipedia.org/wiki/Cartilage_oligomeric_matrix_protein] synonym: "serum COMP level" RELATED [] is_a: CMO:0001956 ! blood cartilage oligomeric matrix protein level created_by: JSmith @@ -17425,7 +17425,7 @@ creation_date: 2013-11-27T15:05:11Z [Term] id: CMO:0001958 name: plasma cartilage oligomeric matrix protein level -def: "The amount of cartilage oligomeric matrix protein (COMP), a noncollagenous extracellular matrix protein that serves as a marker of cartilage turnover, in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, RGD:736605, Wikipedia:http\://en.wikipedia.org/wiki/Cartilage_oligomeric_matrix_protein] +def: "The amount of cartilage oligomeric matrix protein (COMP), a noncollagenous extracellular matrix protein that serves as a marker of cartilage turnover, in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, RGD:736605, https://en.wikipedia.org/wiki/Cartilage_oligomeric_matrix_protein] synonym: "plasma COMP level" RELATED [] is_a: CMO:0001956 ! blood cartilage oligomeric matrix protein level created_by: JSmith @@ -17642,7 +17642,7 @@ creation_date: 2013-12-02T16:36:52Z [Term] id: CMO:0001982 name: spinal cord MHC class II protein measurement -def: "Any quantification of one or more of the major histocompatibility complex (MHC) class II molecules of the spinal cord. MHC class II is a group of proteins that are involved in antigen presentation and self recognition, and have been implicated in allograft rejection and autoimmunity." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Major_histocompatibility_complex] +def: "Any quantification of one or more of the major histocompatibility complex (MHC) class II molecules of the spinal cord. MHC class II is a group of proteins that are involved in antigen presentation and self recognition, and have been implicated in allograft rejection and autoimmunity." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, https://en.wikipedia.org/wiki/Major_histocompatibility_complex] synonym: "Not4Curation" RELATED [] is_a: CMO:0002123 ! spinal cord protein/peptide composition measurement created_by: JSmith @@ -17698,7 +17698,7 @@ creation_date: 2013-12-02T18:18:12Z [Term] id: CMO:0001988 name: brain spike-and-wave discharge severity grade -def: "A measurement based on scoring the severity, for example on a scale of 0-4, of spike and wave discharges, a series of regular, symmetrical, generalized abnormal electrical discharges in the brain." [PMID:15030491, Wikipedia:Wikipedia\:http\://en.wikipedia.org/wiki/Spike_and_Wave] +def: "A measurement based on scoring the severity, for example on a scale of 0-4, of spike and wave discharges, a series of regular, symmetrical, generalized abnormal electrical discharges in the brain." [PMID:15030491, http://en.wikipedia.org/wiki/Spike_and_Wave] synonym: "brain spike-wave activity severity grade" RELATED [] synonym: "brain spike-wave discharge severity grade" EXACT [] synonym: "brain SWD severity grade" RELATED [] @@ -17738,7 +17738,7 @@ creation_date: 2013-12-03T11:31:45Z [Term] id: CMO:0001992 name: percentage of study population developing experimental diabetes mellitus during a period of time -def: "The number of new cases of experimental diabetes mellitus appearing in a study population during a specified period compared to the total number of individuals in the study population, expressed as a percentage. Experimental DM is diabetes induced experimentally by administration of various diabetogenic agents or by removal of all or part of the pancreas." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] +def: "The number of new cases of experimental diabetes mellitus appearing in a study population during a specified period compared to the total number of individuals in the study population, expressed as a percentage. Experimental DM is diabetes induced experimentally by administration of various diabetogenic agents or by removal of all or part of the pancreas." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] synonym: "experimental diabetes mellitus incidence" RELATED [] xref: MESH:D003921 is_a: CMO:0001114 ! percentage of study population developing diabetes mellitus during a period of time @@ -17748,7 +17748,7 @@ creation_date: 2013-12-03T11:39:34Z [Term] id: CMO:0001993 name: percentage of study population displaying experimental diabetes mellitus at a point in time -def: "The number of individuals in a study population which display experimental diabetes mellitus at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. Experimental DM is diabetes induced experimentally by administration of various diabetogenic agents or by removal of all or part of the pancreas." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] +def: "The number of individuals in a study population which display experimental diabetes mellitus at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage. Experimental DM is diabetes induced experimentally by administration of various diabetogenic agents or by removal of all or part of the pancreas." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] synonym: "experimental diabetes mellitus prevalence" RELATED [] xref: MESH:D003921 is_a: CMO:0001115 ! percentage of study population displaying diabetes mellitus at a point in time @@ -17767,7 +17767,7 @@ creation_date: 2013-12-03T17:06:00Z [Term] id: CMO:0001995 name: post-insult time to onset of type 2 diabetes mellitus -def: "Measurement of the length of time between introduction of a disease-producing stimulus and the observation of symptoms of type 2 diabetes mellitus (T2DM). T2DM is a form of diabetes often, although not universally, associated with obesity, insulin resistance, hyperlipidemia(s) and cardiovascular symptoms such as hypertension." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] +def: "Measurement of the length of time between introduction of a disease-producing stimulus and the observation of symptoms of type 2 diabetes mellitus (T2DM). T2DM is a form of diabetes often, although not universally, associated with obesity, insulin resistance, hyperlipidemia(s) and cardiovascular symptoms such as hypertension." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, https://en.wikipedia.org/wiki/Diabetes_mellitus_type_2] synonym: "latency of induced type 2 diabetes mellitus" RELATED [] is_a: CMO:0001582 ! post-insult time to onset of diabetes mellitus created_by: JSmith @@ -17776,7 +17776,7 @@ creation_date: 2013-12-03T17:09:13Z [Term] id: CMO:0001996 name: post-insult time to onset of type 1 diabetes mellitus -def: "Measurement of the length of time between introduction of a disease-producing stimulus and the observation of symptoms of type 1 diabetes mellitus (T1DM). T1DM is a form of diabetes mellitus which results from the autoimmune destruction of beta cells of the pancreatic islets of Langerhans." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Wikipedia:http\://en.wikipedia.org/wiki/Diabetes_mellitus_type_1] +def: "Measurement of the length of time between introduction of a disease-producing stimulus and the observation of symptoms of type 1 diabetes mellitus (T1DM). T1DM is a form of diabetes mellitus which results from the autoimmune destruction of beta cells of the pancreatic islets of Langerhans." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, https://en.wikipedia.org/wiki/Diabetes_mellitus_type_1] synonym: "latency of induced type 1 diabetes mellitus" RELATED [] is_a: CMO:0001582 ! post-insult time to onset of diabetes mellitus created_by: JSmith @@ -17869,7 +17869,7 @@ creation_date: 2013-12-06T17:25:31Z [Term] id: CMO:0002006 name: squamous cell carcinoma of the oral cavity measurement -def: "Any value resulting from the quantification of a morphological or physiological parameter related to tumors arising in the oral cavity, i.e. the mouth, from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "Any value resulting from the quantification of a morphological or physiological parameter related to tumors arising in the oral cavity, i.e. the mouth, from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion. A tumor is an abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] synonym: "squamous cell carcinoma of the mouth measurement" RELATED [] xref: MESH:D009062 is_a: CMO:0001872 ! squamous cell carcinoma of the head and neck measurement @@ -17879,7 +17879,7 @@ creation_date: 2013-12-06T17:33:32Z [Term] id: CMO:0002007 name: squamous cell carcinoma of the oral cavity tumor number -def: "A value or quantity determined by count of tumors arising in the mouth from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma] +def: "A value or quantity determined by count of tumors arising in the mouth from the uncontrolled multiplication of cells of the epithelium, or of cells showing the particular cytological characteristics of squamous cell differentiation, such as the presence of keratin, tonofilament bundles, or desmosomes, structures involved in cell-to-cell adhesion." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Squamous_cell_carcinoma] synonym: "squamous cell carcinoma of the mouth tumor number" RELATED [] xref: MESH:D002294 xref: MESH:D009062 @@ -17947,7 +17947,7 @@ creation_date: 2013-12-09T18:45:32Z [Term] id: CMO:0002014 name: neurilemmoma incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display neurilemmoma at a point in time or develop neurilemmoma within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. A neurilemmoma is a tumor originating in a myelin nerve sheath and arising from Schwann cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Schwannoma] +def: "Any measurement in which the number of individuals in a study population that display neurilemmoma at a point in time or develop neurilemmoma within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. A neurilemmoma is a tumor originating in a myelin nerve sheath and arising from Schwann cells." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Schwannoma] synonym: "malignant peripheral nerve sheath tumor incidence/prevalence measurement" RELATED [] synonym: "MPNST incidence/prevalence measurement" RELATED [] xref: MESH:D009442 @@ -17959,7 +17959,7 @@ creation_date: 2013-12-09T18:47:22Z [Term] id: CMO:0002015 name: trigeminal nerve neurilemmoma incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display trigeminal nerve neurilemmoma at a point in time or develop trigeminal nerve neurilemmoma within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. A trigeminal nerve neurilemmoma is a tumor originating in the myelin sheath of the trigeminal nerve, either of the fifth pair of cranial nerves which function as the chief sensory nerves of the face and the motor nerves of the muscles of mastication." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Schwannoma] +def: "Any measurement in which the number of individuals in a study population that display trigeminal nerve neurilemmoma at a point in time or develop trigeminal nerve neurilemmoma within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. A trigeminal nerve neurilemmoma is a tumor originating in the myelin sheath of the trigeminal nerve, either of the fifth pair of cranial nerves which function as the chief sensory nerves of the face and the motor nerves of the muscles of mastication." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Schwannoma] synonym: "trigeminal malignant peripheral nerve sheath tumor incidence/prevalence measurement" RELATED [] synonym: "trigeminal nerve MPNST incidence/prevalence measurement" RELATED [] xref: MESH:D009442 @@ -17970,7 +17970,7 @@ creation_date: 2013-12-09T18:48:27Z [Term] id: CMO:0002016 name: percentage of study population displaying trigeminal nerve neurilemmomas at a point in time -def: "Any measurement in which the number of individuals in a study population that display trigeminal nerve neurilemmomas at a point in time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. A trigeminal nerve neurilemmoma is a tumor originating in the myelin sheath of the trigeminal nerve, either of the fifth pair of cranial nerves which function as the chief sensory nerves of the face and the motor nerves of the muscles of mastication." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Schwannoma] +def: "Any measurement in which the number of individuals in a study population that display trigeminal nerve neurilemmomas at a point in time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. A trigeminal nerve neurilemmoma is a tumor originating in the myelin sheath of the trigeminal nerve, either of the fifth pair of cranial nerves which function as the chief sensory nerves of the face and the motor nerves of the muscles of mastication." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Schwannoma] synonym: "percentage of study population displaying trigeminal nerve malignant peripheral nerve sheath tumors at a point in time" RELATED [] synonym: "percentage of study population displaying trigeminal nerve MPNST at a point in time" RELATED [] synonym: "trigeminal nerve neurilemmoma prevalence" RELATED [] @@ -17982,7 +17982,7 @@ creation_date: 2013-12-09T18:50:56Z [Term] id: CMO:0002017 name: percentage of study population developing trigeminal nerve neurilemmomas during a period of time -def: "Any measurement in which the number of individuals in a study population that develop trigeminal nerve neurilemmomas within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. A trigeminal nerve neurilemmoma is a tumor originating in the myelin sheath of the trigeminal nerve, either of the fifth pair of cranial nerves which function as the chief sensory nerves of the face and the motor nerves of the muscles of mastication." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Schwannoma] +def: "Any measurement in which the number of individuals in a study population that develop trigeminal nerve neurilemmomas within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. A trigeminal nerve neurilemmoma is a tumor originating in the myelin sheath of the trigeminal nerve, either of the fifth pair of cranial nerves which function as the chief sensory nerves of the face and the motor nerves of the muscles of mastication." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Schwannoma] synonym: "percentage of study population developing trigeminal nerve malignant peripheral nerve sheath tumors during a period of time" RELATED [] synonym: "percentage of study population developing trigeminal nerve MPNST during a period of time" RELATED [] synonym: "trigeminal nerve neurilemmoma incidence" RELATED [] @@ -17994,7 +17994,7 @@ creation_date: 2013-12-09T18:51:02Z [Term] id: CMO:0002018 name: neurilemmoma onset/diagnosis measurement -def: "Any measurement which expresses a quantity related to the beginning, early stages or development of neurilemmomas, or to the official determination of neurilemmomas as the cause of the observed symptom(s). A neurilemmoma is a tumor originating from Schwann cells in a myelin nerve sheath." [McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Wikipedia:http\://en.wikipedia.org/wiki/Schwannoma] +def: "Any measurement which expresses a quantity related to the beginning, early stages or development of neurilemmomas, or to the official determination of neurilemmomas as the cause of the observed symptom(s). A neurilemmoma is a tumor originating from Schwann cells in a myelin nerve sheath." [McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, https://en.wikipedia.org/wiki/Schwannoma] synonym: "malignant peripheral nerve sheath tumor onset/diagnosis measurement" RELATED [] synonym: "MPNST onset/diagnosis measurement" RELATED [] xref: MESH:D009442 @@ -18006,7 +18006,7 @@ creation_date: 2013-12-09T18:59:01Z [Term] id: CMO:0002019 name: post-insult time to trigeminal nerve neurilemmoma formation -def: "Measurement of the length of time between introduction of a disease-producing stimulus and the observation of trigeminal nerve neurilemmomas - tumors originating in the myelin sheath of the trigeminal nerve, either of the fifth pair of cranial nerves which function as the chief sensory nerves of the face and the motor nerves of the muscles of mastication." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Wikipedia:http\://en.wikipedia.org/wiki/Schwannoma] +def: "Measurement of the length of time between introduction of a disease-producing stimulus and the observation of trigeminal nerve neurilemmomas - tumors originating in the myelin sheath of the trigeminal nerve, either of the fifth pair of cranial nerves which function as the chief sensory nerves of the face and the motor nerves of the muscles of mastication." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, https://en.wikipedia.org/wiki/Schwannoma] synonym: "post-insult time to trigeminal nerve malignant peripheral nerve sheath tumor formation" RELATED [] synonym: "post-insult time to trigeminal nerve MPNST formation" RELATED [] synonym: "post-insult time to trigeminal nerve neurilemmoma onset" RELATED [] @@ -18018,7 +18018,7 @@ creation_date: 2013-12-09T19:00:48Z [Term] id: CMO:0002020 name: neurilemmoma measurement -def: "Any quantification related to neurilemmoma, a tumor originating in a myelin nerve sheath and arising from Schwann cells." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Schwannoma] +def: "Any quantification related to neurilemmoma, a tumor originating in a myelin nerve sheath and arising from Schwann cells." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Schwannoma] synonym: "malignant peripheral nerve sheath tumor measurement" RELATED [] synonym: "MPNST measurement" RELATED [] xref: MESH:D009442 @@ -18153,7 +18153,7 @@ creation_date: 2013-12-16T18:10:56Z [Term] id: CMO:0002034 name: absolute change in blood glucose level area under curve -def: "The difference in blood glucose level area under curve (blood glucose AUC) between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. Blood glucose AUC is a calculated value in which a series of measurements of the amount of glucose in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Collins:Collins_Online_English_Dictionary, Mondofacto:Mondofacto_Online_Medical_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F, Wikipedia:http\://en.wikipedia.org/wiki/Area_under_curve] +def: "The difference in blood glucose level area under curve (blood glucose AUC) between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. Blood glucose AUC is a calculated value in which a series of measurements of the amount of glucose in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Collins:Collins_Online_English_Dictionary, Mondofacto:Mondofacto_Online_Medical_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F, https://en.wikipedia.org/wiki/Area_under_curve] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in glucose AUC" RELATED [] is_a: CMO:0000350 ! blood glucose level area under curve (AUC) @@ -18191,7 +18191,7 @@ creation_date: 2014-01-07T16:53:44Z [Term] id: CMO:0002038 name: absolute change in serum insulin level -def: "The difference in serum insulin level between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in serum insulin level between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0000359 ! calculated serum insulin level created_by: JSmith @@ -18217,7 +18217,7 @@ creation_date: 2014-01-08T16:46:13Z [Term] id: CMO:0002041 name: serum uric acid level -def: "The amount of uric acid, a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen,the end product of purine catabolism, in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org] +def: "The amount of uric acid, a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen,the end product of purine catabolism, in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org] is_a: CMO:0000501 ! blood uric acid level created_by: JSmith creation_date: 2014-01-08T16:54:34Z @@ -18225,7 +18225,7 @@ creation_date: 2014-01-08T16:54:34Z [Term] id: CMO:0002042 name: plasma uric acid level -def: "The amount of uric acid, a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen,the end product of purine catabolism, in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org] +def: "The amount of uric acid, a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen,the end product of purine catabolism, in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org] is_a: CMO:0000501 ! blood uric acid level created_by: JSmith creation_date: 2014-01-08T16:54:37Z @@ -18241,7 +18241,7 @@ creation_date: 2014-01-23T16:21:57Z [Term] id: CMO:0002044 name: absolute change in body weight -def: "The difference in the entire weight of the body of an organism between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in the entire weight of the body of an organism between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0002045 ! change in body weight created_by: JSmith @@ -18267,7 +18267,7 @@ creation_date: 2014-01-23T16:48:36Z [Term] id: CMO:0002047 name: measurement of prepulse inhibition of the acoustic startle response -def: "A measurment of the neurological phenomenon in which a weaker prestimulus (prepulse) inhibits the reaction of an organism to a subsequent strong startling stimulus (pulse), that is, a measurement of the reduction in the amplitude of the startle movement caused by an acoustic stimulus/insult following a prepulse." [Wikipedia:http\://en.wikipedia.org/wiki/Prepulse_Inhibition] +def: "A measurment of the neurological phenomenon in which a weaker prestimulus (prepulse) inhibits the reaction of an organism to a subsequent strong startling stimulus (pulse), that is, a measurement of the reduction in the amplitude of the startle movement caused by an acoustic stimulus/insult following a prepulse." [https://en.wikipedia.org/wiki/Prepulse_Inhibition] synonym: "measurement of prepulse inhibition of the acoustic startle reaction" EXACT [] is_a: CMO:0002046 ! calculated acoustic startle response measurement created_by: JSmith @@ -18303,7 +18303,7 @@ creation_date: 2014-01-23T17:04:53Z [Term] id: CMO:0002051 name: blood phytosterol level -def: "The amount of one or more phytosterols in a specified sample of blood. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [Wikipedia:http\://en.wikipedia.org/wiki/Phytosterol] +def: "The amount of one or more phytosterols in a specified sample of blood. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [https://en.wikipedia.org/wiki/Phytosterol] is_a: CMO:0002048 ! blood sterol level created_by: JSmith creation_date: 2014-01-23T17:10:08Z @@ -18311,7 +18311,7 @@ creation_date: 2014-01-23T17:10:08Z [Term] id: CMO:0002052 name: serum phytosterol level -def: "The amount of one or more phytosterols in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Phytosterol] +def: "The amount of one or more phytosterols in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Phytosterol] is_a: CMO:0002049 ! serum sterol level is_a: CMO:0002051 ! blood phytosterol level created_by: JSmith @@ -18320,7 +18320,7 @@ creation_date: 2014-01-23T17:11:15Z [Term] id: CMO:0002053 name: mean duration of a single spike-and-wave discharge train -def: "Measurement of the average duration of a single set of spike and wave discharges, regular, symmetrical, generalized abnormal electrical discharges in the brain, in a series of episodes separated by normal brain activity, i.e. the average length of time which a spike and wave discharge episode lasts." [PMID:15270755, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the average duration of a single set of spike and wave discharges, regular, symmetrical, generalized abnormal electrical discharges in the brain, in a series of episodes separated by normal brain activity, i.e. the average length of time which a spike and wave discharge episode lasts." [PMID:15270755, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "average brain spike-and-wave discharge duration" RELATED [] synonym: "mean brain spike-and-wave discharge duration" RELATED [] is_a: CMO:0001738 ! brain spike-and-wave discharge measurement @@ -18330,7 +18330,7 @@ creation_date: 2014-01-23T18:31:20Z [Term] id: CMO:0002054 name: brain type II spike-and-wave discharge amplitude -def: "Measurement of the maximum deviation from the baseline position of the electrical signal during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Website:http\://www.physicsclassroom.com/class/waves/u10l2a.cfm#amplitude, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the maximum deviation from the baseline position of the electrical signal during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, http://www.physicsclassroom.com/class/waves/u10l2a.cfm#amplitude, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain type II spike-wave activity amplitude" RELATED [] synonym: "brain type II spike-wave discharge amplitude" EXACT [] synonym: "brain type II SWD amplitude" RELATED [] @@ -18341,7 +18341,7 @@ creation_date: 2014-01-23T18:58:07Z [Term] id: CMO:0002055 name: brain type I spike-and-wave discharge amplitude -def: "Measurement of the maximum deviation from the baseline position of the electrical signal during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Website:http\://www.physicsclassroom.com/class/waves/u10l2a.cfm#amplitude, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the maximum deviation from the baseline position of the electrical signal during a series of regular, symmetrical, generalized abnormal electrical discharges in the brain. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, http://www.physicsclassroom.com/class/waves/u10l2a.cfm#amplitude, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain type I spike-wave activity amplitude" RELATED [] synonym: "brain type I spike-wave discharge amplitude" EXACT [] synonym: "brain type I SWD amplitude" RELATED [] @@ -18352,7 +18352,7 @@ creation_date: 2014-01-23T18:51:19Z [Term] id: CMO:0002056 name: brain type I spike-and-wave discharge frequency -def: "Measurement of the number of individual type I spike-and-wave discharge cycles occurring per second. A spike-and-wave discharge is a series of regular, symmetrical abnormal electrical discharges in the brain. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, Website:http\://www.biogetic.com/research.html, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the number of individual type I spike-and-wave discharge cycles occurring per second. A spike-and-wave discharge is a series of regular, symmetrical abnormal electrical discharges in the brain. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, http://www.biogetic.com/research.html, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain type I spike-wave activity frequency" RELATED [] synonym: "brain type I spike-wave discharge frequency" EXACT [] synonym: "brain type I SWD frequency" RELATED [] @@ -18363,7 +18363,7 @@ creation_date: 2014-01-23T19:02:02Z [Term] id: CMO:0002057 name: brain type II spike-and-wave discharge frequency -def: "Measurement of the number of individual type II spike-and-wave discharge cycles occurring per second. A spike-and-wave discharge is a series of regular, symmetrical abnormal electrical discharges in the brain. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, Website:http\://www.biogetic.com/research.html, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the number of individual type II spike-and-wave discharge cycles occurring per second. A spike-and-wave discharge is a series of regular, symmetrical abnormal electrical discharges in the brain. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, http://www.biogetic.com/research.html, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain type II spike-wave activity frequency" RELATED [] synonym: "brain type II spike-wave discharge frequency" EXACT [] synonym: "brain type II SWD frequency" RELATED [] @@ -18374,7 +18374,7 @@ creation_date: 2014-01-23T19:04:49Z [Term] id: CMO:0002058 name: brain type I spike-and-wave discharge rate -def: "Measurement of the number of periods of type I spike-and-wave discharges occurring per unit of time. A spike-and-wave discharge is a series of regular, symmetrical, generalized abnormal electrical discharges in the brain. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the number of periods of type I spike-and-wave discharges occurring per unit of time. A spike-and-wave discharge is a series of regular, symmetrical, generalized abnormal electrical discharges in the brain. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain type I spike-wave activity rate" RELATED [] synonym: "brain type I spike-wave discharge rate" EXACT [] synonym: "brain type I SWD rate" RELATED [] @@ -18385,7 +18385,7 @@ creation_date: 2014-01-23T19:07:51Z [Term] id: CMO:0002059 name: brain type II spike-and-wave discharge rate -def: "Measurement of the number of periods of type II spike-and-wave discharges occurring per unit of time. A spike-and-wave discharge is a series of regular, symmetrical, generalized abnormal electrical discharges in the brain. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the number of periods of type II spike-and-wave discharges occurring per unit of time. A spike-and-wave discharge is a series of regular, symmetrical, generalized abnormal electrical discharges in the brain. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain type II spike-wave activity rate" RELATED [] synonym: "brain type II spike-wave discharge rate" EXACT [] synonym: "brain type II SWD rate" RELATED [] @@ -18396,7 +18396,7 @@ creation_date: 2014-01-23T19:10:13Z [Term] id: CMO:0002060 name: brain type I spike-and-wave discharge severity grade -def: "A measurement based on scoring the severity, for example on a scale of 0-4, of type I spike and wave discharges, a series of regular, symmetrical, generalized abnormal electrical discharges in the brain characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [PMID:15030491, PMID:15270755, Wikipedia:Wikipedia\:http\://en.wikipedia.org/wiki/Spike_and_Wave] +def: "A measurement based on scoring the severity, for example on a scale of 0-4, of type I spike and wave discharges, a series of regular, symmetrical, generalized abnormal electrical discharges in the brain characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [PMID:15030491, PMID:15270755, http://en.wikipedia.org/wiki/Spike_and_Wave] synonym: "brain type I spike-wave activity severity grade" RELATED [] synonym: "brain type I spike-wave discharge severity grade" EXACT [] synonym: "brain type I SWD severity grade" RELATED [] @@ -18407,7 +18407,7 @@ creation_date: 2014-01-23T19:12:14Z [Term] id: CMO:0002061 name: brain type II spike-and-wave discharge severity grade -def: "A measurement based on scoring the severity, for example on a scale of 0-4, of type II spike and wave discharges, a series of regular, symmetrical, generalized abnormal electrical discharges in the brain characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [PMID:15030491, PMID:15270755, Wikipedia:Wikipedia\:http\://en.wikipedia.org/wiki/Spike_and_Wave] +def: "A measurement based on scoring the severity, for example on a scale of 0-4, of type II spike and wave discharges, a series of regular, symmetrical, generalized abnormal electrical discharges in the brain characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [PMID:15030491, PMID:15270755, http://en.wikipedia.org/wiki/Spike_and_Wave] synonym: "brain type II spike-wave activity severity grade" RELATED [] synonym: "brain type II spike-wave discharge severity grade" EXACT [] synonym: "brain type II SWD severity grade" RELATED [] @@ -18418,7 +18418,7 @@ creation_date: 2014-01-23T19:14:07Z [Term] id: CMO:0002062 name: brain total type I spike-and-wave discharge duration -def: "Measurement of the cumulated duration of type I spike and wave discharges occurring per unit of time during a series of regular, symmetrical, generalized abnormal electrical discharge episodes in the brain. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the cumulated duration of type I spike and wave discharges occurring per unit of time during a series of regular, symmetrical, generalized abnormal electrical discharge episodes in the brain. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain total type I spike-wave activity duration" RELATED [] synonym: "brain total type I spike-wave discharge duration" EXACT [] synonym: "brain total type I SWD duration" RELATED [] @@ -18430,7 +18430,7 @@ creation_date: 2014-01-23T19:16:10Z [Term] id: CMO:0002063 name: brain total type II spike-and-wave discharge duration -def: "Measurement of the cumulated duration of type II spike and wave discharges occurring per unit of time during a series of regular, symmetrical, generalized abnormal electrical discharge episodes in the brain. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, Website:http\://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the cumulated duration of type II spike and wave discharges occurring per unit of time during a series of regular, symmetrical, generalized abnormal electrical discharge episodes in the brain. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:15270755, http://www.epilepsyfoundation.org/aboutepilepsy/Diagnosis/examandtests/eeg.cfm, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "brain total type II spike-wave activity duration" RELATED [] synonym: "brain total type II spike-wave discharge duration" EXACT [] synonym: "brain total type II SWD duration" RELATED [] @@ -18442,7 +18442,7 @@ creation_date: 2014-01-23T19:19:59Z [Term] id: CMO:0002064 name: mean duration of a single type I spike-and-wave discharge train -def: "Measurement of the average duration of a single set of type I spike and wave discharges, regular, symmetrical, generalized abnormal electrical discharges in the brain, in a series of episodes separated by normal brain activity, i.e. the average length of time which a type I spike and wave discharge episode lasts. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [PMID:15270755, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the average duration of a single set of type I spike and wave discharges, regular, symmetrical, generalized abnormal electrical discharges in the brain, in a series of episodes separated by normal brain activity, i.e. the average length of time which a type I spike and wave discharge episode lasts. Type I is characterized by immediate, bilaterally symmetric discharges, generalized over the cortex, lasting longer than type II, and displaying an upward polarity in the spikes." [PMID:15270755, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "average brain type I spike-and-wave discharge duration" RELATED [] synonym: "mean brain type I spike-and-wave discharge duration" RELATED [] is_a: CMO:0002053 ! mean duration of a single spike-and-wave discharge train @@ -18452,7 +18452,7 @@ creation_date: 2014-01-23T19:21:47Z [Term] id: CMO:0002065 name: mean duration of a single type II spike-and-wave discharge train -def: "Measurement of the average duration of a single set of type II spike and wave discharges, regular, symmetrical, generalized abnormal electrical discharges in the brain, in a series of episodes separated by normal brain activity, i.e. the average length of time which a type II spike and wave discharge episode lasts. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [PMID:15270755, Wikipedia:http\://en.wikipedia.org/wiki/Spike-and-wave] +def: "Measurement of the average duration of a single set of type II spike and wave discharges, regular, symmetrical, generalized abnormal electrical discharges in the brain, in a series of episodes separated by normal brain activity, i.e. the average length of time which a type II spike and wave discharge episode lasts. Type II is characterized by local occipital-parietal discharges that are shorter and have less clear waves than spike-wave discharge type I and display an downward polarity in the spikes." [PMID:15270755, https://en.wikipedia.org/wiki/Spike-and-wave] synonym: "average brain type II spike-and-wave discharge duration" RELATED [] synonym: "mean brain type II spike-and-wave discharge duration" RELATED [] is_a: CMO:0002053 ! mean duration of a single spike-and-wave discharge train @@ -18907,7 +18907,7 @@ creation_date: 2014-01-27T13:12:36Z [Term] id: CMO:0002111 name: serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum -def: "A calculated measurement of the amount in a specified sample of serum of rheumatoid factor that is expressed as an immunoglobulin M (IgM) molecule in which the level of antibody is normalized to an arbitrary reference value or reference standard. Rheumatoid factor (RF) is an autoantibody against the Fc portion of IgG found in rheumatoid arthritis and some other autoimmune diseases. RF and IgG join to form immune complexes that contribute to the disease process." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, PMID:14674011, Wikipedia:http\://en.wikipedia.org/wiki/Rheumatoid_factor] +def: "A calculated measurement of the amount in a specified sample of serum of rheumatoid factor that is expressed as an immunoglobulin M (IgM) molecule in which the level of antibody is normalized to an arbitrary reference value or reference standard. Rheumatoid factor (RF) is an autoantibody against the Fc portion of IgG found in rheumatoid arthritis and some other autoimmune diseases. RF and IgG join to form immune complexes that contribute to the disease process." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, PMID:14674011, https://en.wikipedia.org/wiki/Rheumatoid_factor] synonym: "serum IgM-RF level normalized to a reference value" RELATED [] synonym: "serum IgM-rheumatoid factor level normalized to a reference value" RELATED [] is_a: CMO:0002609 ! serum immunoglobulin M-type rheumatoid factor level @@ -18917,7 +18917,7 @@ creation_date: 2014-01-27T13:14:29Z [Term] id: CMO:0002112 name: serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum -def: "A calculated measurement of the amount in a specified sample of serum of rheumatoid factor that is expressed as an immunoglobulin G (IgG) molecule in which the level of antibody is normalized to an arbitrary reference value or reference standard. Rheumatoid factor (RF) is an autoantibody against the Fc portion of IgG found in rheumatoid arthritis and some other autoimmune diseases. RF and IgG join to form immune complexes that contribute to the disease process." [PMID:14674011, Wikipedia:http\://en.wikipedia.org/wiki/Rheumatoid_factor] +def: "A calculated measurement of the amount in a specified sample of serum of rheumatoid factor that is expressed as an immunoglobulin G (IgG) molecule in which the level of antibody is normalized to an arbitrary reference value or reference standard. Rheumatoid factor (RF) is an autoantibody against the Fc portion of IgG found in rheumatoid arthritis and some other autoimmune diseases. RF and IgG join to form immune complexes that contribute to the disease process." [PMID:14674011, https://en.wikipedia.org/wiki/Rheumatoid_factor] synonym: "serum IgG-RF level normalized to an arbitrary reference level" RELATED [] synonym: "serum IgG-rheumatoid factor level normalized to an arbitrary reference level" RELATED [] is_a: CMO:0002610 ! serum immunoglobulin G-type rheumatoid factor level @@ -18936,7 +18936,7 @@ creation_date: 2014-01-27T13:37:33Z [Term] id: CMO:0002114 name: serum immunoglobulin G subclass level -def: "The amount in a specified sample of serum of one of the subclasses of immunoglobulin G (IgG), the most abundant class of antibodies found in blood serum and lymph. IgG antibodies are active against bacteria, fungi, viruses, and foreign particles, and trigger action of the complement system. IgG subclasses differ in the structure of their hinge regions." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Immunoglobulin_G] +def: "The amount in a specified sample of serum of one of the subclasses of immunoglobulin G (IgG), the most abundant class of antibodies found in blood serum and lymph. IgG antibodies are active against bacteria, fungi, viruses, and foreign particles, and trigger action of the complement system. IgG subclasses differ in the structure of their hinge regions." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Immunoglobulin_G] synonym: "serum IgG subclass level" EXACT [] synonym: "serum IgG subtype level" RELATED [] synonym: "serum immunoglobulin G subtype level" RELATED [] @@ -18947,7 +18947,7 @@ creation_date: 2014-01-27T14:52:10Z [Term] id: CMO:0002115 name: serum immunoglobulin G1 level -def: "The amount in a specified sample of serum of the G1 subclass of immunoglobulin G (IgG), the most abundant class of antibodies found in blood serum and lymph. IgG antibodies are active against bacteria, fungi, viruses, and foreign particles, and trigger action of the complement system. IgG subclasses differ in the structure of their hinge regions. IgG1 is the most abundant subclass in serum, and is able to activate complement and bind to the Fc receptor on phagocytic cells." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Immunoglobulin_G] +def: "The amount in a specified sample of serum of the G1 subclass of immunoglobulin G (IgG), the most abundant class of antibodies found in blood serum and lymph. IgG antibodies are active against bacteria, fungi, viruses, and foreign particles, and trigger action of the complement system. IgG subclasses differ in the structure of their hinge regions. IgG1 is the most abundant subclass in serum, and is able to activate complement and bind to the Fc receptor on phagocytic cells." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Immunoglobulin_G] synonym: "serum IgG1 level" EXACT [] is_a: CMO:0002114 ! serum immunoglobulin G subclass level created_by: JSmith @@ -18956,7 +18956,7 @@ creation_date: 2014-01-27T14:57:46Z [Term] id: CMO:0002116 name: serum immunoglobulin G2a level -def: "The amount in a specified sample of serum of the G2a subclass of immunoglobulin G (IgG), the most abundant class of antibodies found in blood serum and lymph. IgG antibodies are active against bacteria, fungi, viruses, and foreign particles, and trigger action of the complement system. IgG subclasses differ in the structure of their hinge regions. IgG2a is able to activate complement and bind to the Fc receptor on phagocytic cells." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Immunoglobulin_G] +def: "The amount in a specified sample of serum of the G2a subclass of immunoglobulin G (IgG), the most abundant class of antibodies found in blood serum and lymph. IgG antibodies are active against bacteria, fungi, viruses, and foreign particles, and trigger action of the complement system. IgG subclasses differ in the structure of their hinge regions. IgG2a is able to activate complement and bind to the Fc receptor on phagocytic cells." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Immunoglobulin_G] synonym: "serum IgG2a level" EXACT [] is_a: CMO:0002114 ! serum immunoglobulin G subclass level created_by: JSmith @@ -19118,7 +19118,7 @@ creation_date: 2014-01-28T12:48:58Z [Term] id: CMO:0002134 name: vocalization measurement -def: "Any measurement of the use of uttered sounds for auditory communication." [WordNet_3_0:http\://www.thefreedictionary.com/vocalization] +def: "Any measurement of the use of uttered sounds for auditory communication." [http://www.thefreedictionary.com/vocalization] synonym: "vocalisation measurement" EXACT [] is_a: CMO:0000000 ! clinical measurement created_by: JSmith @@ -19127,7 +19127,7 @@ creation_date: 2014-01-28T13:58:16Z [Term] id: CMO:0002135 name: calculated vocalization measurement -def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the use of uttered sounds for auditory communication." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, WordNet_3_0:http\://www.thefreedictionary.com/vocalization] +def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the use of uttered sounds for auditory communication." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://www.thefreedictionary.com/vocalization] synonym: "calculated vocalisation measurement" RELATED [] is_a: CMO:0002134 ! vocalization measurement created_by: JSmith @@ -19277,7 +19277,7 @@ creation_date: 2014-01-30T18:48:43Z [Term] id: CMO:0002152 name: absolute change in left rear ankle joint diameter -def: "A calculated measurement of the difference in left rear ankle joint diameter between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "A calculated measurement of the difference in left rear ankle joint diameter between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0002149 ! left rear ankle joint diameter is_a: CMO:0002151 ! calculated ankle joint diameter @@ -19287,7 +19287,7 @@ creation_date: 2014-01-30T18:55:36Z [Term] id: CMO:0002153 name: absolute change in right rear ankle joint diameter -def: "A calculated measurement of the difference in right rear ankle joint diameter between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "A calculated measurement of the difference in right rear ankle joint diameter between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. is_a: CMO:0002150 ! right rear ankle joint diameter is_a: CMO:0002151 ! calculated ankle joint diameter @@ -19297,7 +19297,7 @@ creation_date: 2014-01-30T18:56:39Z [Term] id: CMO:0002154 name: absolute change in the sum of right rear ankle joint diameter and left rear ankle joint diameter -def: "A calculated measurement of the difference in the total of the right and left rear ankle joint diameters added together between two points in time or two conditions expressed as the result of the subtraction of the sums in and of itself without comparison by ratio with another quantity." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "A calculated measurement of the difference in the total of the right and left rear ankle joint diameters added together between two points in time or two conditions expressed as the result of the subtraction of the sums in and of itself without comparison by ratio with another quantity." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in the total left plus right rear ankle diameter" RELATED [] is_a: CMO:0002149 ! left rear ankle joint diameter @@ -19370,7 +19370,7 @@ creation_date: 2014-01-31T16:39:20Z [Term] id: CMO:0002162 name: absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio -def: "The difference between two points in time or two conditions in heart rate expressed as the ratio of the low frequency R-R interval component of the power spectrum analysis to the high frequency R-R interval component of the power spectrum analysis, expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, PMID:7815012, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference between two points in time or two conditions in heart rate expressed as the ratio of the low frequency R-R interval component of the power spectrum analysis to the high frequency R-R interval component of the power spectrum analysis, expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, PMID:7815012, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in ECG LF/HF ratio" RELATED [] synonym: "absolute change in EKG LF/HF ratio" RELATED [] @@ -19383,7 +19383,7 @@ creation_date: 2014-01-31T16:41:23Z [Term] id: CMO:0002163 name: pituicyte measurement -def: "Any value resulting from the quantification of a morphological or physiological parameter of a pituicyte, a glial-type cell of the posterior pituitary whose main role is to assist in the storage and release of neurohypophysial hormones such as oxytocin and vasopressin." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Pituicyte] +def: "Any value resulting from the quantification of a morphological or physiological parameter of a pituicyte, a glial-type cell of the posterior pituitary whose main role is to assist in the storage and release of neurohypophysial hormones such as oxytocin and vasopressin." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, https://en.wikipedia.org/wiki/Pituicyte] is_a: CMO:0000227 ! cell measurement created_by: JSmith creation_date: 2014-02-03T16:13:24Z @@ -19400,7 +19400,7 @@ creation_date: 2014-02-03T17:42:14Z [Term] id: CMO:0002165 name: heart left ventricle natriuretic peptide A level -def: "The amount in a specified sample of tissue from the heart left ventricle, of natriuretic peptide A (NPPA), a powerful vasodilator and peptide hormone secreted mainly by heart muscle cells and involved in control of extracellular fluid volume and electrolyte homeostasis." [RGD:730878, Wikipedia:http\://en.wikipedia.org/wiki/Atrial_natriuretic_peptide] +def: "The amount in a specified sample of tissue from the heart left ventricle, of natriuretic peptide A (NPPA), a powerful vasodilator and peptide hormone secreted mainly by heart muscle cells and involved in control of extracellular fluid volume and electrolyte homeostasis." [RGD:730878, https://en.wikipedia.org/wiki/Atrial_natriuretic_peptide] synonym: "heart left ventricle atrial natriuretic factor level" EXACT [] synonym: "heart left ventricle natriuretic peptide A protein level" EXACT [] synonym: "heart left ventricle NPPA level" RELATED [] @@ -19411,7 +19411,7 @@ creation_date: 2014-02-03T17:43:11Z [Term] id: CMO:0002166 name: kidney renin level -def: "The amount of renin in a specified sample of kidney tissue. Renin, an aspartyl protease, catalyzes the cleavage of angiotensinogen to form angiotensin I, the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure." [RGD:736366, Wikipedia:http\://en.wikipedia.org/wiki/Renin] +def: "The amount of renin in a specified sample of kidney tissue. Renin, an aspartyl protease, catalyzes the cleavage of angiotensinogen to form angiotensin I, the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure." [RGD:736366, https://en.wikipedia.org/wiki/Renin] synonym: "kidney renin protein level" EXACT [] synonym: "kidney REN level" RELATED [] is_a: CMO:0001177 ! kidney protein/peptide composition measurement @@ -19431,7 +19431,7 @@ creation_date: 2014-02-03T18:09:26Z [Term] id: CMO:0002168 name: binary logarithm of pituitary gland wet weight -def: "A calculated measurement corresponding to the power to which the number 2 must be raised to obtain the specified value for the wet weight of the pituitary gland." [Wikipedia:http\://en.wikipedia.org/wiki/Binary_logarithm] +def: "A calculated measurement corresponding to the power to which the number 2 must be raised to obtain the specified value for the wet weight of the pituitary gland." [https://en.wikipedia.org/wiki/Binary_logarithm] synonym: "base 2 logarithm of pituitary gland wet weight" EXACT [] synonym: "log2 of pituitary gland wet weight" RELATED [] is_a: CMO:0000616 ! calculated pituitary gland weight @@ -19492,7 +19492,7 @@ creation_date: 2014-03-03T17:56:13Z [Term] id: CMO:0002174 name: bisphenol A drink intake rate -def: "The amount of a solution of bisphenol A that is consumed as a drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., per unit time. Bisphenol A (BPA) is a synthetic phenolic compound with the chemical formula (CH3)2C(C6H4OH)2, i.e. one in which a central carbon links to two methyl groups and two hydroxyphenyl groups. BPA is similar in structure to estradiol and can bind to and activate the estrogen receptor." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Bisphenol_A] +def: "The amount of a solution of bisphenol A that is consumed as a drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., per unit time. Bisphenol A (BPA) is a synthetic phenolic compound with the chemical formula (CH3)2C(C6H4OH)2, i.e. one in which a central carbon links to two methyl groups and two hydroxyphenyl groups. BPA is similar in structure to estradiol and can bind to and activate the estrogen receptor." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Bisphenol_A] synonym: "BPA drink intake rate" RELATED [] is_a: CMO:0000455 ! drink intake rate created_by: JSmith @@ -19519,7 +19519,7 @@ creation_date: 2014-03-05T15:31:59Z [Term] id: CMO:0002177 name: food calorie intake rate -def: "The number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism per period of time. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the food." [Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "The number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism per period of time. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the food." [https://en.wikipedia.org/wiki/Calorie] synonym: "calorie intake rate from food" EXACT [] synonym: "food energy intake rate" RELATED [] is_a: CMO:0000427 ! food intake rate @@ -19530,7 +19530,7 @@ creation_date: 2014-03-05T15:51:17Z [Term] id: CMO:0002178 name: total food calorie intake rate -def: "The entire number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism per period of time, i.e., the calorie intake rate from all food sources." [Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "The entire number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism per period of time, i.e., the calorie intake rate from all food sources." [https://en.wikipedia.org/wiki/Calorie] synonym: "total food energy intake rate" RELATED [] is_a: CMO:0002177 ! food calorie intake rate created_by: JSmith @@ -19539,7 +19539,7 @@ creation_date: 2014-03-05T15:52:38Z [Term] id: CMO:0002179 name: fructose food calorie intake rate -def: "The number of calories derived from fructose consumed in food by an organism per period of time, i.e., the calorie intake rate for fructose only. Fructose is one of three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is covalently bound to glucose to form the sucrose molecule, and is found naturally in honey and many sweet fruits." [Wikipedia:http\://en.wikipedia.org/wiki/Fructose] +def: "The number of calories derived from fructose consumed in food by an organism per period of time, i.e., the calorie intake rate for fructose only. Fructose is one of three dietary monosaccharides that are absorbed directly into the bloodstream during digestion, is covalently bound to glucose to form the sucrose molecule, and is found naturally in honey and many sweet fruits." [https://en.wikipedia.org/wiki/Fructose] synonym: "fructose food energy intake rate" RELATED [] is_a: CMO:0002177 ! food calorie intake rate created_by: JSmith @@ -19572,7 +19572,7 @@ creation_date: 2014-03-06T15:16:13Z [Term] id: CMO:0002183 name: whole body visceral fat volume -def: "Measurement of the size of the entire three dimensional space occupied by the fat inside the major body cavity or cavities of an organism, especially the fat which surrounds and cushions the internal organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, American_Heritage:The_American_Heritage_Science_Dictionary_2005, USDA:http\://agclass.nal.usda.gov/mtwdk.exe?s=1&n=1&y=0&l=60&k=glossary&t=2&w=visceral+fat] +def: "Measurement of the size of the entire three dimensional space occupied by the fat inside the major body cavity or cavities of an organism, especially the fat which surrounds and cushions the internal organs." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, American_Heritage:The_American_Heritage_Science_Dictionary_2005, http://agclass.nal.usda.gov/mtwdk.exe?s=1&n=1&y=0&l=60&k=glossary&t=2&w=visceral+fat] is_a: CMO:0002180 ! body fat volume created_by: JSmith creation_date: 2014-03-06T15:22:47Z @@ -19702,7 +19702,7 @@ creation_date: 2014-03-06T15:58:24Z [Term] id: CMO:0002198 name: fructose drink intake rate -def: "Amount of a fructose solution consumed as a drink per unit time. Fructose is one of three dietary monosaccharides that are absorbed directly into the bloodstream during digestion. It is found naturally in honey and many sweet fruits and can be covalently bound to glucose to form the sucrose molecule." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Fructose] +def: "Amount of a fructose solution consumed as a drink per unit time. Fructose is one of three dietary monosaccharides that are absorbed directly into the bloodstream during digestion. It is found naturally in honey and many sweet fruits and can be covalently bound to glucose to form the sucrose molecule." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Fructose] xref: CHEBI:15824 xref: CHEBI:28757 is_a: CMO:0000455 ! drink intake rate @@ -19783,7 +19783,7 @@ creation_date: 2014-03-07T13:45:37Z [Term] id: CMO:0002206 name: food calorie intake measurement -def: "Any measurement of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the food." [Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "Any measurement of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the food." [https://en.wikipedia.org/wiki/Calorie] synonym: "food energy intake measurement" RELATED [] is_a: CMO:0000772 ! food intake measurement is_a: CMO:0002248 ! calorie intake measurement @@ -19793,7 +19793,7 @@ creation_date: 2014-03-10T11:33:52Z [Term] id: CMO:0002207 name: calculated food calorie intake measurement -def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism per period of time. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the food." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism per period of time. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the food." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Calorie] synonym: "calculated food energy intake measurement" RELATED [] is_a: CMO:0001774 ! calculated food intake measurement is_a: CMO:0002206 ! food calorie intake measurement @@ -19803,7 +19803,7 @@ creation_date: 2014-03-10T13:06:25Z [Term] id: CMO:0002208 name: total food calorie intake level -def: "Measurement of the entire number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the food." [Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "Measurement of the entire number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the food." [https://en.wikipedia.org/wiki/Calorie] synonym: "total food-derived calorie intake level" RELATED [] synonym: "total food-derived energy intake level" RELATED [] synonym: "total food energy intake level" RELATED [] @@ -19814,7 +19814,7 @@ creation_date: 2014-03-10T13:08:35Z [Term] id: CMO:0002209 name: food calorie intake level to change in body weight ratio -def: "A calculated measurement in which the number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism during a specified period of time or under specified conditions, is divided by corresponding difference in body weight during that same period of time or under the same conditions, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "A calculated measurement in which the number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism during a specified period of time or under specified conditions, is divided by corresponding difference in body weight during that same period of time or under the same conditions, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Calorie] synonym: "food calorie intake level to body weight gain ratio" RELATED [] synonym: "food calorie intake level to gain in body weight ratio" RELATED [] synonym: "food energy intake level to change in body weight ratio" RELATED [] @@ -19852,7 +19852,7 @@ creation_date: 2014-03-10T13:21:16Z [Term] id: CMO:0002213 name: food calorie intake level to body weight ratio -def: "A calculated measurement in which the number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism during a specified period of time or under specified conditions, is divided by the total weight of the body of the organism, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "A calculated measurement in which the number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as food by an organism during a specified period of time or under specified conditions, is divided by the total weight of the body of the organism, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Calorie] synonym: "food energy intake level to body weight ratio" RELATED [] is_a: CMO:0002207 ! calculated food calorie intake measurement created_by: JSmith @@ -19952,7 +19952,7 @@ creation_date: 2014-03-10T17:51:03Z [Term] id: CMO:0002225 name: kidney glucose-6-phosphate dehydrogenase activity to total protein level ratio -def: "A calculated measurement in which the level of glucose-6-phosphate dehydrogenase enzyme activity in a specified sample of kidney is divided by the weight of total protein in that sample. Glucose-6-phosphate dehydrogenase catalizes the conversion of D-glucose 6-phosphate + NADP+ to 6-phospho-D-glucono-1,5-lactone + NADPH." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Glucose-6-phosphate_dehydrogenase] +def: "A calculated measurement in which the level of glucose-6-phosphate dehydrogenase enzyme activity in a specified sample of kidney is divided by the weight of total protein in that sample. Glucose-6-phosphate dehydrogenase catalizes the conversion of D-glucose 6-phosphate + NADP+ to 6-phospho-D-glucono-1,5-lactone + NADPH." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Glucose-6-phosphate_dehydrogenase] synonym: "kidney G6PD activity to total protein level ratio" RELATED [] is_a: CMO:0002223 ! kidney enzyme activity measurement created_by: JSmith @@ -19970,7 +19970,7 @@ creation_date: 2014-03-10T17:53:05Z [Term] id: CMO:0002227 name: kidney glutathione peroxidase activity to total protein level ratio -def: "A calculated measurement in which the level of glutathione peroxidase enzyme activity in a specified sample of kidney is divided by the weight of total protein in that sample. Glutathione peroxidases constitute a family of proteins that reduce lipid hydroperoxides to their corresponding alcohols and reduce free hydrogen peroxide to water." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione_peroxidase] +def: "A calculated measurement in which the level of glutathione peroxidase enzyme activity in a specified sample of kidney is divided by the weight of total protein in that sample. Glutathione peroxidases constitute a family of proteins that reduce lipid hydroperoxides to their corresponding alcohols and reduce free hydrogen peroxide to water." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Glutathione_peroxidase] is_a: CMO:0002223 ! kidney enzyme activity measurement created_by: JSmith creation_date: 2014-03-10T17:54:38Z @@ -19978,7 +19978,7 @@ creation_date: 2014-03-10T17:54:38Z [Term] id: CMO:0002228 name: kidney glutathione-S-transferase activity to total protein level ratio -def: "A calculated measurement in which the level of glutathione-S-transferase enzyme activity in a specified sample of kidney is divided by the weight of total protein in that sample. Glutathione-S-transferase refers to any of a family of proteins with the ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione_S-transferase] +def: "A calculated measurement in which the level of glutathione-S-transferase enzyme activity in a specified sample of kidney is divided by the weight of total protein in that sample. Glutathione-S-transferase refers to any of a family of proteins with the ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Glutathione_S-transferase] is_a: CMO:0002223 ! kidney enzyme activity measurement created_by: JSmith creation_date: 2014-03-10T17:55:21Z @@ -20036,7 +20036,7 @@ creation_date: 2014-03-10T17:59:34Z [Term] id: CMO:0002235 name: kidney glutathione level -def: "The amount of glutathione in a specified sample of kidney tissue. Glutathione (GSH/GSSG) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of glutathione in a specified sample of kidney tissue. Glutathione (GSH/GSSG) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [https://en.wikipedia.org/wiki/Glutathione] synonym: "kidney GSH level" RELATED [] xref: CHEBI:16856 is_a: CMO:0001177 ! kidney protein/peptide composition measurement @@ -20046,7 +20046,7 @@ creation_date: 2014-03-10T18:02:47Z [Term] id: CMO:0002236 name: kidney malondialdehyde level -def: "The amount of malondialdehyde in a specified sample of kidney tissue. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress." [Wikipedia:http\://en.wikipedia.org/wiki/Malondialdehyde] +def: "The amount of malondialdehyde in a specified sample of kidney tissue. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress." [https://en.wikipedia.org/wiki/Malondialdehyde] xref: CHEBI:566274 is_a: CMO:0001852 ! kidney molecular composition measurement created_by: JSmith @@ -20072,7 +20072,7 @@ creation_date: 2014-03-10T18:06:09Z [Term] id: CMO:0002239 name: blood gamma-glutamyltransferase activity level -def: "The amount of enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of blood. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Blood GGT level is used as an enzymatic marker for liver disease or damage." [Wikipedia:http\://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase] +def: "The amount of enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of blood. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Blood GGT level is used as an enzymatic marker for liver disease or damage." [https://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase] synonym: "blood gamma-glutamyl transpeptidase activity level" EXACT [] synonym: "blood GGT activity level" RELATED [] synonym: "blood GGTP activity level" RELATED [] @@ -20083,7 +20083,7 @@ creation_date: 2014-03-11T14:08:40Z [Term] id: CMO:0002240 name: plasma gamma-glutamyltransferase activity level -def: "The amount of enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of plasma. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Plasma GGT level is used as an enzymatic marker for liver disease or damage." [Wikipedia:http\://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase] +def: "The amount of enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of plasma. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Plasma GGT level is used as an enzymatic marker for liver disease or damage." [https://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase] synonym: "plasma gamma-glutamyl transpeptidase activity level" EXACT [] synonym: "plasma GGT activity level" RELATED [] synonym: "plasma GGTP activity level" RELATED [] @@ -20094,7 +20094,7 @@ creation_date: 2014-03-11T14:10:08Z [Term] id: CMO:0002241 name: serum gamma-glutamyltransferase activity level -def: "The amount of enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of serum. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Serum GGT level is used as an enzymatic marker for liver disease or damage." [Wikipedia:http\://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase] +def: "The amount of enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of serum. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Serum GGT level is used as an enzymatic marker for liver disease or damage." [https://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase] synonym: "serum gamma-glutamyl transpeptidase activity level" EXACT [] synonym: "serum GGT activity level" RELATED [] synonym: "serum GGTP activity level" RELATED [] @@ -20105,7 +20105,7 @@ creation_date: 2014-03-11T14:10:11Z [Term] id: CMO:0002242 name: blood creatine kinase activity level -def: "The amount of enzymatic activity of creatine kinase (CK) enzyme in a specified sample of blood. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Blood CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [RGD:737472, Wikipedia:http\://en.wikipedia.org/wiki/Creatine_kinase] +def: "The amount of enzymatic activity of creatine kinase (CK) enzyme in a specified sample of blood. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Blood CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [RGD:737472, https://en.wikipedia.org/wiki/Creatine_kinase] synonym: "blood CK activity level" RELATED [] synonym: "blood CPK activity level" RELATED [] synonym: "blood creatine phosphokinase activity level" EXACT [] @@ -20116,7 +20116,7 @@ creation_date: 2014-03-11T14:12:54Z [Term] id: CMO:0002243 name: plasma creatine kinase activity level -def: "The amount of enzymatic activity of creatine kinase (CK) enzyme in a specified sample of plasma. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Plasma CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [RGD:737472, Wikipedia:http\://en.wikipedia.org/wiki/Creatine_kinase] +def: "The amount of enzymatic activity of creatine kinase (CK) enzyme in a specified sample of plasma. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Plasma CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [RGD:737472, https://en.wikipedia.org/wiki/Creatine_kinase] synonym: "plasma CK activity level" RELATED [] synonym: "plasma CPK activity level" RELATED [] synonym: "plasma creatine phosphokinase activity level" EXACT [] @@ -20127,7 +20127,7 @@ creation_date: 2014-03-11T14:14:23Z [Term] id: CMO:0002244 name: serum creatine kinase activity level -def: "The amount of enzymatic activity of creatine kinase (CK) enzyme in a specified sample of serum. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Serum CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [RGD:737472, Wikipedia:http\://en.wikipedia.org/wiki/Creatine_kinase] +def: "The amount of enzymatic activity of creatine kinase (CK) enzyme in a specified sample of serum. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Serum CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [RGD:737472, https://en.wikipedia.org/wiki/Creatine_kinase] synonym: "serum CK activity level" RELATED [] synonym: "serum CPK activity level" RELATED [] synonym: "serum creatine phosphokinase activity level" EXACT [] @@ -20151,7 +20151,7 @@ creation_date: 2014-03-11T14:32:07Z [Term] id: CMO:0002246 name: kidney lipid peroxide level -def: "The amount of lipid peroxidation end products in a specified sample of kidney tissue. Lipid peroxidation is the oxidative degradation of lipids." [Wikipedia:http\://en.wikipedia.org/wiki/Lipid_peroxidation] +def: "The amount of lipid peroxidation end products in a specified sample of kidney tissue. Lipid peroxidation is the oxidative degradation of lipids." [https://en.wikipedia.org/wiki/Lipid_peroxidation] synonym: "kidney lipid peroxidation level" RELATED [] synonym: "kidney LPO level" RELATED [] is_a: CMO:0001853 ! kidney lipid composition measurement @@ -20169,7 +20169,7 @@ creation_date: 2014-03-12T15:00:11Z [Term] id: CMO:0002248 name: calorie intake measurement -def: "Any measurement of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed by an organism. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the source of those calories, i.e., a food, a drink, or both." [Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "Any measurement of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed by an organism. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the source of those calories, i.e., a food, a drink, or both." [https://en.wikipedia.org/wiki/Calorie] synonym: "energy intake measurement" RELATED [] is_a: CMO:0000426 ! consumption measurement created_by: JSmith @@ -20178,7 +20178,7 @@ creation_date: 2014-03-12T15:38:12Z [Term] id: CMO:0002249 name: drink calorie intake measurement -def: "Any measurement of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as drink by an organism. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the drink." [Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "Any measurement of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as drink by an organism. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the drink." [https://en.wikipedia.org/wiki/Calorie] synonym: "drink energy intake measurement" RELATED [] is_a: CMO:0000771 ! drink intake measurement is_a: CMO:0002248 ! calorie intake measurement @@ -20358,7 +20358,7 @@ creation_date: 2014-03-13T17:42:05Z [Term] id: CMO:0002269 name: percentage of study population displaying kidney tubular degeneration at a point in time -def: "A measurement in which the number of individuals in a study population that display kidney tubular degeneration, that is, deterioration of the renal tubules especially with a resulting loss of function, at a point in time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.wisegeek.com/what-is-the-renal-tubule.htm] +def: "A measurement in which the number of individuals in a study population that display kidney tubular degeneration, that is, deterioration of the renal tubules especially with a resulting loss of function, at a point in time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.wisegeek.com/what-is-the-renal-tubule.htm] synonym: "kidney tubular degeneration prevalence" RELATED [] synonym: "percentage of study population displaying renal tubular degeneration at a point in time" RELATED [] synonym: "renal tubular degeneration prevalence" RELATED [] @@ -20369,7 +20369,7 @@ creation_date: 2014-03-13T18:24:59Z [Term] id: CMO:0002270 name: percentage of study population developing kidney tubular degeneration during a period of time -def: "A measurement in which the number of individuals in a study population that develop kidney tubular degeneration, that is, deterioration of the renal tubules especially with a resulting loss of function, within a determined period of time, are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.wisegeek.com/what-is-the-renal-tubule.htm] +def: "A measurement in which the number of individuals in a study population that develop kidney tubular degeneration, that is, deterioration of the renal tubules especially with a resulting loss of function, within a determined period of time, are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.wisegeek.com/what-is-the-renal-tubule.htm] synonym: "kidney tubular degeneration incidence" RELATED [] synonym: "percentage of study population developing renal tubular degeneration during a period of time" EXACT [] synonym: "renal tubular degeneration incidence" RELATED [] @@ -20380,7 +20380,7 @@ creation_date: 2014-03-13T18:24:59Z [Term] id: CMO:0002271 name: kidney tubular degeneration incidence/prevalence measurement -def: "A measurement in which the number of individuals in a study population that display kidney tubular degeneration, that is, deterioration of the renal tubules especially with a resulting loss of function, at a point in time or develop kidney tubular degeneration within a determined period of time, are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.wisegeek.com/what-is-the-renal-tubule.htm] +def: "A measurement in which the number of individuals in a study population that display kidney tubular degeneration, that is, deterioration of the renal tubules especially with a resulting loss of function, at a point in time or develop kidney tubular degeneration within a determined period of time, are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.wisegeek.com/what-is-the-renal-tubule.htm] synonym: "renal tubular degeneration incidence/prevalence measurement" EXACT [] is_a: CMO:0002255 ! kidney non-tumorous lesion incidence/prevalence measurement created_by: JSmith @@ -20416,7 +20416,7 @@ creation_date: 2014-03-13T18:39:31Z [Term] id: CMO:0002275 name: myeloid leukemia incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display myeloid leukemia, a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid (that is, non-lymphocytic) cells in the bone marrow and the accumulation of these cells in the bone marrow and/or blood, at a point in time or develop myeloid leukemia within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Myeloid_leukemia] +def: "Any measurement in which the number of individuals in a study population that display myeloid leukemia, a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid (that is, non-lymphocytic) cells in the bone marrow and the accumulation of these cells in the bone marrow and/or blood, at a point in time or develop myeloid leukemia within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Myeloid_leukemia] xref: MESH:D007951 is_a: CMO:0001266 ! leukemia incidence/prevalence measurement created_by: JSmith @@ -20425,7 +20425,7 @@ creation_date: 2014-03-24T12:00:09Z [Term] id: CMO:0002276 name: percentage of study population displaying myeloid leukemia at a point in time -def: "The number of individuals in a study population which display myeloid leukemia, a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid (that is, non-lymphocytic) cells in the bone marrow and the accumulation of these cells in the bone marrow and/or blood, at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Myeloid_leukemia] +def: "The number of individuals in a study population which display myeloid leukemia, a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid (that is, non-lymphocytic) cells in the bone marrow and the accumulation of these cells in the bone marrow and/or blood, at a certain point in time compared to the total number of individuals in the study population, expressed as a percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Myeloid_leukemia] synonym: "myeloid leukemia prevalence" RELATED [] xref: MESH:D007951 is_a: CMO:0001268 ! percentage of study population displaying leukemia at a point in time @@ -20436,7 +20436,7 @@ creation_date: 2014-03-24T12:07:06Z [Term] id: CMO:0002277 name: percentage of study population developing myeloid leukemia during a period of time -def: "The number of new cases of myeloid leukemia, a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid (that is, non-lymphocytic) cells in the bone marrow and the accumulation of these cells in the bone marrow and/or blood, appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wkipedia:http\://en.wikipedia.org/wiki/Myeloid_leukemia] +def: "The number of new cases of myeloid leukemia, a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid (that is, non-lymphocytic) cells in the bone marrow and the accumulation of these cells in the bone marrow and/or blood, appearing in a study population during a certain period compared to the total number of individuals in the study population, expressed as a percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://en.wikipedia.org/wiki/Myeloid_leukemia] synonym: "myeloid leukemia incidence" RELATED [] xref: MESH:D007951 is_a: CMO:0001267 ! percentage of study population developing leukemia during a period of time @@ -20529,7 +20529,7 @@ creation_date: 2014-03-25T11:36:49Z [Term] id: CMO:0002286 name: stomach tumor incidence/prevalence measurement -def: "A measurement in which the number of individuals in a study population displaying one or more tumors of the stomach (the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion) at a point in time or developing stomach tumors within a determined period of time, are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Stomach] +def: "A measurement in which the number of individuals in a study population displaying one or more tumors of the stomach (the curved, muscular, saclike structure that is an enlargement of the alimentary canal between the esophagus and the small intestine, and that temporarily holds food and secretes proteases and strong acids to aid in food digestion) at a point in time or developing stomach tumors within a determined period of time, are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Stomach] synonym: "gastric tumor incidence/prevalence measurement" EXACT [] synonym: "Not4Curation" RELATED [] xref: MESH:D013274 @@ -20608,7 +20608,7 @@ creation_date: 2014-03-25T17:08:54Z [Term] id: CMO:0002293 name: absolute change in tilted plane angle at loss of balance/traction -def: "The difference between two conditions or between two points in time (expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity) of the angle of inclination, i.e., the degree of divergence from the horizontal, of a surface at the point when a subject sitting or standing on that surface can no longer maintain its balance or remain in a stable position." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F, Website:http\://www.thefreedictionary.com/angle] +def: "The difference between two conditions or between two points in time (expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity) of the angle of inclination, i.e., the degree of divergence from the horizontal, of a surface at the point when a subject sitting or standing on that surface can no longer maintain its balance or remain in a stable position." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F, http://www.thefreedictionary.com/angle] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in the angle of a tilted plane at which balance/traction is lost" RELATED [] is_a: CMO:0002292 ! calculated balance measurement @@ -20618,7 +20618,7 @@ creation_date: 2014-03-25T17:11:34Z [Term] id: CMO:0002294 name: tilted plane angle at loss of balance/traction -def: "The angle of inclination, i.e., the degree of divergence from the horizontal, of a surface at the point when a subject sitting or standing on that surface can no longer maintain its balance or remain in a stable position." [Website:http\://www.thefreedictionary.com/angle] +def: "The angle of inclination, i.e., the degree of divergence from the horizontal, of a surface at the point when a subject sitting or standing on that surface can no longer maintain its balance or remain in a stable position." [http://www.thefreedictionary.com/angle] synonym: "angle of a tilted plane at which balance/traction is lost" RELATED [] is_a: CMO:0001767 ! balance measurement created_by: JSmith @@ -20627,7 +20627,7 @@ creation_date: 2014-03-25T17:13:35Z [Term] id: CMO:0002295 name: post insult time to regain baseline tilted plane angle at loss of balance/traction -def: "Measurement of the length of time between introduction of a stimulus or effector and the timepoint at which the angle of inclination, i.e., the degree of divergence from the horizontal, of a surface at the moment when a subject sitting or standing on that surface can no longer maintain its balance or remain in a stable position, is the same as the value of that angle before the introduction of the stimulus or effector." [McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Website:http\://www.thefreedictionary.com/angle] +def: "Measurement of the length of time between introduction of a stimulus or effector and the timepoint at which the angle of inclination, i.e., the degree of divergence from the horizontal, of a surface at the moment when a subject sitting or standing on that surface can no longer maintain its balance or remain in a stable position, is the same as the value of that angle before the introduction of the stimulus or effector." [McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, http://www.thefreedictionary.com/angle] synonym: "post insult time to achieve baseline angle of tilted plane at time of balance/traction loss" RELATED [] synonym: "post insult time to regain baseline angle of tilted plane at which balance/traction is lost" RELATED [] is_a: CMO:0001767 ! balance measurement @@ -20770,7 +20770,7 @@ creation_date: 2014-03-28T18:17:45Z [Term] id: CMO:0002311 name: bone trabecular cross-sectional area -def: "The portion of the cross-sectional area of a bone that corresponds to the area occupied by cancellous or spongy bone, the inner, less dense, more metabolically active type of osseous tissue made up of a network of tiny lattice-shaped spicules often containing marrow. The cross-sectional area of bone is the measurement of the extent of a plane through, that is, perpendicular to the longest axis of a bone, the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Trabecular_bone] +def: "The portion of the cross-sectional area of a bone that corresponds to the area occupied by cancellous or spongy bone, the inner, less dense, more metabolically active type of osseous tissue made up of a network of tiny lattice-shaped spicules often containing marrow. The cross-sectional area of bone is the measurement of the extent of a plane through, that is, perpendicular to the longest axis of a bone, the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Trabecular_bone] synonym: "cancellous bone cross-sectional area" RELATED [] synonym: "spongy bone cross-sectional area" RELATED [] is_a: CMO:0001693 ! bone cross-sectional area measurement @@ -20924,7 +20924,7 @@ creation_date: 2014-04-22T16:38:54Z [Term] id: CMO:0002327 name: drink calorie intake level to change in body weight ratio -def: "A calculated measurement in which the number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as drink by an organism during a specified period of time or under specified conditions, is divided by corresponding difference in body weight during that same period of time or under the same conditions, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "A calculated measurement in which the number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as drink by an organism during a specified period of time or under specified conditions, is divided by corresponding difference in body weight during that same period of time or under the same conditions, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Calorie] synonym: "drink calorie intake level to body weight gain ratio" RELATED [] synonym: "drink calorie intake level to gain in body weight ratio" RELATED [] synonym: "drink energy intake level to change in body weight ratio" RELATED [] @@ -20935,7 +20935,7 @@ creation_date: 2014-04-23T13:27:54Z [Term] id: CMO:0002328 name: drink calorie intake level to body weight ratio -def: "A calculated measurement in which the number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as drink by an organism during a specified period of time or under specified conditions, is divided by the total weight of the body of the organism, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "A calculated measurement in which the number of calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as drink by an organism during a specified period of time or under specified conditions, is divided by the total weight of the body of the organism, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Calorie] synonym: "drink energy intake level to body weight ratio" RELATED [] is_a: CMO:0002329 ! calculated drink calorie intake measurement created_by: JSmith @@ -20944,7 +20944,7 @@ creation_date: 2014-04-23T13:27:54Z [Term] id: CMO:0002329 name: calculated drink calorie intake measurement -def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as drink by an organism per period of time. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the drink." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Calorie] +def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the calories (usually large calories, kilogram calories, dietary calories, or nutritional calories) consumed as drink by an organism per period of time. A large calorie is the amount of energy needed to raise the temperature of one kilogram of water by one degree Celsius, a measure of the energy which an organism can derive by metabolizing the drink." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Calorie] synonym: "calculated drink energy intake measurement" RELATED [] is_a: CMO:0002249 ! drink calorie intake measurement is_a: CMO:0002330 ! calculated drink intake measurement @@ -20954,7 +20954,7 @@ creation_date: 2014-04-23T13:27:54Z [Term] id: CMO:0002330 name: calculated drink intake measurement -def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation of any parameter related to the process whereby drink, any liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., is taken in for utilization by the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, YourDictionary:http\://www.yourdictionary.com/drink] +def: "Any measurement which has been normalized, adjusted or derived by a mathematical process or computation of any parameter related to the process whereby drink, any liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., is taken in for utilization by the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://www.yourdictionary.com/drink] synonym: "Not4Curation" RELATED [] is_a: CMO:0000771 ! drink intake measurement created_by: JSmith @@ -20963,7 +20963,7 @@ creation_date: 2014-04-23T13:36:26Z [Term] id: CMO:0002331 name: calculated drink intake weight -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the weight or heaviness of the drink, that is, the liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed in a specified period of time." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, YourDictionary:http\://www.yourdictionary.com/drink] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the weight or heaviness of the drink, that is, the liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed in a specified period of time." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://www.yourdictionary.com/drink] synonym: "Not4Curation" RELATED [] is_a: CMO:0001762 ! drink intake weight is_a: CMO:0002330 ! calculated drink intake measurement @@ -20973,7 +20973,7 @@ creation_date: 2014-04-23T13:45:25Z [Term] id: CMO:0002332 name: calculated drink intake rate -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed per unit time." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, YourDictionary:http\://www.yourdictionary.com/drink] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed per unit time." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://www.yourdictionary.com/drink] is_a: CMO:0000455 ! drink intake rate is_a: CMO:0002330 ! calculated drink intake measurement created_by: JSmith @@ -20982,7 +20982,7 @@ creation_date: 2014-04-23T13:50:40Z [Term] id: CMO:0002333 name: calculated drink intake volume -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the size of the three dimensional space occupied by the amount of drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed in a specified period of time." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, YourDictionary:http\://www.yourdictionary.com/drink] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the size of the three dimensional space occupied by the amount of drink, that is, a liquid that is brought into the mouth and swallowed to quench thirst, for nourishment, etc., consumed in a specified period of time." [American_Heritage:The_American_Heritage_Science_Dictionary_2005, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://www.yourdictionary.com/drink] synonym: "Not4Curation" RELATED [] is_a: CMO:0000773 ! drink intake volume is_a: CMO:0002330 ! calculated drink intake measurement @@ -21009,7 +21009,7 @@ creation_date: 2014-04-24T11:17:53Z [Term] id: CMO:0002336 name: blood band neutrophil count -def: "The number of granulocytes categorized as band neutrophils in a specified volume of blood. A band neutrophil is an immature neutrophil with a horse-shoe or parallel-sided shaped nucleus and represents the final stage of differentiation before the mature segmented neutrophil." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-0323057479, ISBN:978-1416049982, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, Website:https\://ahdc.vet.cornell.edu/clinpath/modules/heme1/neutr.htm] +def: "The number of granulocytes categorized as band neutrophils in a specified volume of blood. A band neutrophil is an immature neutrophil with a horse-shoe or parallel-sided shaped nucleus and represents the final stage of differentiation before the mature segmented neutrophil." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-0323057479, ISBN:978-1416049982, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, https://ahdc.vet.cornell.edu/clinpath/modules/heme1/neutr.htm] synonym: "band neutrophil granulocyte count" EXACT [] synonym: "rod neutrophil count" RELATED [] synonym: "stab form leukocyte count" RELATED [] @@ -21050,7 +21050,7 @@ creation_date: 2014-04-24T12:17:30Z [Term] id: CMO:0002339 name: non-specified leukocyte count to total leukocyte count ratio -def: "A calculated measurement in which the number of white blood cells that have not been identified as a specific type of cell is divided by the total number of leukocytes in a specified sample of blood, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, NBRP-Rat:http\://www.anim.med.kyoto-u.ac.jp/nbr/strainsx/hematology_list.aspx, RGD:JRS] +def: "A calculated measurement in which the number of white blood cells that have not been identified as a specific type of cell is divided by the total number of leukocytes in a specified sample of blood, and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.anim.med.kyoto-u.ac.jp/nbr/strainsx/hematology_list.aspx, RGD:JRS] comment: This is not the total percentage of leukocytes (e.g. compared to all cells including RBCs) in a sample, but rather is for use when a series of differential percentages is given followed by a number for the percent of WBCs which do not fit into any other category. synonym: "non-specified leukocyte percentage" RELATED [] synonym: "percentage of non-categorized leukocytes" RELATED [] @@ -21064,7 +21064,7 @@ creation_date: 2014-04-24T12:27:55Z [Term] id: CMO:0002340 name: blood non-specified leukocyte count -def: "The number of white blood cells that have not been identified or categorized as a specific type of cell in a specified sample of blood." [NBRP-Rat:http\://www.anim.med.kyoto-u.ac.jp/nbr/strainsx/hematology_list.aspx, RGD:JRS] +def: "The number of white blood cells that have not been identified or categorized as a specific type of cell in a specified sample of blood." [http://www.anim.med.kyoto-u.ac.jp/nbr/strainsx/hematology_list.aspx, RGD:JRS] comment: This is not the total number of leukocytes in a sample, but rather is for use when a series of differential counts is given followed by a number for WBCs which do not fit into any other category. synonym: "count of non-categorized leukocytes" RELATED [] synonym: "count of white blood cells of unspecified type" RELATED [] @@ -21197,7 +21197,7 @@ creation_date: 2014-05-14T13:03:18Z [Term] id: CMO:0002353 name: blood natural killer cell count to total lymphocyte count ratio -def: "A calculated measurement in which the number of natural killer (NK) cells in a specified sample of blood is divided by the total number of lymphocytes in the sample, and the result presented as a ratio, fraction, quotient or percentage. NK cells are cells capable of mediating cytotoxic reactions without themselves being specifically sensitized against the target and are critical to the innate immune system." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://www.rndsystems.com/molecule_group.aspx?g=2851&r=4&g2=695] +def: "A calculated measurement in which the number of natural killer (NK) cells in a specified sample of blood is divided by the total number of lymphocytes in the sample, and the result presented as a ratio, fraction, quotient or percentage. NK cells are cells capable of mediating cytotoxic reactions without themselves being specifically sensitized against the target and are critical to the innate immune system." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://www.rndsystems.com/molecule_group.aspx?g=2851&r=4&g2=695] synonym: "blood natural killer cell percentage" RELATED [] synonym: "blood NK cell count to total lymphocyte count ratio" RELATED [] synonym: "blood NK cell percentage" RELATED [] @@ -21208,7 +21208,7 @@ creation_date: 2014-05-14T13:04:31Z [Term] id: CMO:0002354 name: blood CD4 lymphocyte count to total lymphocyte count ratio -def: "A calculated measurement in which the number of lymphocytes expressing the CD4 antigen on their surface in a specified sample of blood is divided by the total number of lymphocytes in the sample, and the result presented as a ratio, fraction, quotient or percentage. CD4 is a membrane glycoprotein found primarily on T lymphocytes, especially T helper (TH) cells, but also can be expressed on B cells, macrophages, and granulocytes. On T cells it is a co-receptor for the T cell receptor (TCR), interacts with MHC class II antigens, and functions to initiate or augment the early phase of T-cell activation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/CD4] +def: "A calculated measurement in which the number of lymphocytes expressing the CD4 antigen on their surface in a specified sample of blood is divided by the total number of lymphocytes in the sample, and the result presented as a ratio, fraction, quotient or percentage. CD4 is a membrane glycoprotein found primarily on T lymphocytes, especially T helper (TH) cells, but also can be expressed on B cells, macrophages, and granulocytes. On T cells it is a co-receptor for the T cell receptor (TCR), interacts with MHC class II antigens, and functions to initiate or augment the early phase of T-cell activation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/CD4] synonym: "blood CD4(+) lymphocyte count to total lymphocyte count ratio" EXACT [] synonym: "blood CD4 lymphocyte count as percentage of total lymphocytes" RELATED [] synonym: "blood TH cell count to total lymphocyte count ratio" RELATED [] @@ -21450,7 +21450,7 @@ creation_date: 2014-05-27T13:10:14Z [Term] id: CMO:0002375 name: absolute change in plasma epinephrine level -def: "The difference in the amount of epinephrine in a specific volume of plasma between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in the amount of epinephrine in a specific volume of plasma between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in plasma adrenaline level" EXACT [] is_a: CMO:0002374 ! calculated plasma epinephrine level @@ -21469,7 +21469,7 @@ creation_date: 2014-05-27T13:18:28Z [Term] id: CMO:0002377 name: absolute change in plasma norepinephrine level -def: "The difference in the amount of norepinephrine in a specific volume of plasma between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in the amount of norepinephrine in a specific volume of plasma between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in plasma noradrenaline level" EXACT [] is_a: CMO:0002376 ! calculated plasma norepinephrine level @@ -21489,7 +21489,7 @@ creation_date: 2014-05-27T13:59:17Z [Term] id: CMO:0002379 name: ratio of the area occupied by protein casts to the total area of the kidney outer medulla outer stripe and cortex -def: "A calculated measurement in which the area occupied by renal protein casts is divided by the total, combined area of the outer stripe of the kidney outer medulla and the kidney cortex, and the result presented as a ratio, fraction, quotient or percentage. Renal protein casts are gelled proteins precipitated in the renal tubules and molded to the tubular lumen. The medulla outer stripe is the section of the renal medula adjacent to the renal cortex and contains portions of the nephron, including the straight proximal tubules, and portions of the loops of henle and outer medullary collecting ducts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:http\://en.wikivet.net/Renal_Anatomy_-_Anatomy_%26_Physiology#Renal_Cortex] +def: "A calculated measurement in which the area occupied by renal protein casts is divided by the total, combined area of the outer stripe of the kidney outer medulla and the kidney cortex, and the result presented as a ratio, fraction, quotient or percentage. Renal protein casts are gelled proteins precipitated in the renal tubules and molded to the tubular lumen. The medulla outer stripe is the section of the renal medula adjacent to the renal cortex and contains portions of the nephron, including the straight proximal tubules, and portions of the loops of henle and outer medullary collecting ducts." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://en.wikivet.net/Renal_Anatomy_-_Anatomy_%26_Physiology#Renal_Cortex] synonym: "percent area of renal protein casting" RELATED [] is_a: CMO:0002378 ! calculated kidney non-tumorous lesion measurement created_by: JSmith @@ -21552,7 +21552,7 @@ creation_date: 2014-05-27T16:50:04Z [Term] id: CMO:0002385 name: anogenital distance -def: "The length of a straight line from the anus to the genitalia, that is, to the base of the genital tubercle in the fetus, to the genital bud in neonatal animals, or to the base of the penis or vagina in older individuals." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Perineum] +def: "The length of a straight line from the anus to the genitalia, that is, to the base of the genital tubercle in the fetus, to the genital bud in neonatal animals, or to the base of the penis or vagina in older individuals." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Perineum] synonym: "AGD" RELATED [] synonym: "perineum length" RELATED [] is_a: CMO:0000021 ! body morphological measurement @@ -21652,7 +21652,7 @@ creation_date: 2014-05-27T17:31:50Z [Term] id: CMO:0002396 name: stomach tumor histology grade -def: "A measurement of degree of abnormality of a stomach tumor based on histological assessment of the differentiation state of the cells comprising the tumor. The grade is derived from a one or more measurements matched against an objective or subjective ranking or rating system according to a specified formula or set of criteria." [Mondofacto:Mondofacto_Online_Medical_Dictionary, Website:http\://www.cancer.gov/cancertopics/factsheet/detection/tumor-grade] +def: "A measurement of degree of abnormality of a stomach tumor based on histological assessment of the differentiation state of the cells comprising the tumor. The grade is derived from a one or more measurements matched against an objective or subjective ranking or rating system according to a specified formula or set of criteria." [Mondofacto:Mondofacto_Online_Medical_Dictionary, http://www.cancer.gov/cancertopics/factsheet/detection/tumor-grade] synonym: "gastric tumor histology grade" EXACT [] synonym: "stomach tumor histological grade" EXACT [] is_a: CMO:0001887 ! stomach tumor measurement @@ -21719,7 +21719,7 @@ creation_date: 2014-05-28T12:26:55Z [Term] id: CMO:0002404 name: percent change in renal sympathetic nerve activity -def: "A calculated measurement of the relative difference in the activity of the renal sympathetic nerve between a treated state and a control state or between two points in time, expressed as a percentage. Percent change is calculated as the difference between the two values divided by the baseline, starting or reference value, and the result multiplied by 100." [Wikipedia:http\://en.wikipedia.org/wiki/Percent_change] +def: "A calculated measurement of the relative difference in the activity of the renal sympathetic nerve between a treated state and a control state or between two points in time, expressed as a percentage. Percent change is calculated as the difference between the two values divided by the baseline, starting or reference value, and the result multiplied by 100." [https://en.wikipedia.org/wiki/Percent_change] synonym: "percent change in RSNA" RELATED [] is_a: CMO:0001785 ! calculated renal sympathetic nerve activity measurement created_by: JSmith @@ -21979,7 +21979,7 @@ creation_date: 2014-05-29T17:40:54Z [Term] id: CMO:0002431 name: metformin drink intake rate -def: "Amount of metformin consumed as or in a drink per unit time. Metformin is an oral antidiabetic drug in the biguanide class which functions to supress the production of glucose by the liver (hepatic gluconeogenesis)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Metformin] +def: "Amount of metformin consumed as or in a drink per unit time. Metformin is an oral antidiabetic drug in the biguanide class which functions to supress the production of glucose by the liver (hepatic gluconeogenesis)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Metformin] xref: CHEBI:6801 is_a: CMO:0000455 ! drink intake rate created_by: JSmith @@ -21988,7 +21988,7 @@ creation_date: 2014-05-29T18:26:58Z [Term] id: CMO:0002432 name: blood glutathione level -def: "The amount of glutathione in a specified sample of blood. Glutathione (GSH) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of glutathione in a specified sample of blood. Glutathione (GSH) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [https://en.wikipedia.org/wiki/Glutathione] is_a: CMO:0000023 ! blood chemistry measurement created_by: JSmith creation_date: 2014-06-05T12:15:43Z @@ -21996,7 +21996,7 @@ creation_date: 2014-06-05T12:15:43Z [Term] id: CMO:0002433 name: serum glutathione level -def: "The amount of glutathione in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Glutathione (GSH) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of glutathione in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Glutathione (GSH) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Glutathione] synonym: "serum GSH level" RELATED [] synonym: "serum reduced glutathione level" NARROW [] is_a: CMO:0002432 ! blood glutathione level @@ -22006,7 +22006,7 @@ creation_date: 2014-06-05T12:17:47Z [Term] id: CMO:0002434 name: plasma glutathione level -def: "The amount of glutathione in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Glutathione (GSH) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of glutathione in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Glutathione (GSH) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Glutathione] synonym: "plasma GSH level" RELATED [] synonym: "plasma reduced glutathione level" NARROW [] is_a: CMO:0002432 ! blood glutathione level @@ -22016,7 +22016,7 @@ creation_date: 2014-06-05T12:17:55Z [Term] id: CMO:0002435 name: serum oxidized glutathione level -def: "The amount of oxidized glutathione (GSSG) in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. GSSG is a molecule produced when glutathione is used as a reducing agent in a biochemical reaction, and consists of a pair of glutathione molecules connected by a disulfide bridge between their cysteine residues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of oxidized glutathione (GSSG) in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. GSSG is a molecule produced when glutathione is used as a reducing agent in a biochemical reaction, and consists of a pair of glutathione molecules connected by a disulfide bridge between their cysteine residues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Glutathione] synonym: "serum GSSG level" RELATED [] is_a: CMO:0002433 ! serum glutathione level is_a: CMO:0002437 ! blood oxidized glutathione level @@ -22026,7 +22026,7 @@ creation_date: 2014-06-05T12:22:49Z [Term] id: CMO:0002436 name: plasma oxidized glutathione level -def: "The amount of oxidized glutathione (GSSG) in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. GSSG is a molecule produced when glutathione is used as a reducing agent in a biochemical reaction, and consists of a pair of glutathione molecules connected by a disulfide bridge between their cysteine residues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of oxidized glutathione (GSSG) in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. GSSG is a molecule produced when glutathione is used as a reducing agent in a biochemical reaction, and consists of a pair of glutathione molecules connected by a disulfide bridge between their cysteine residues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Glutathione] synonym: "plasma GSSG level" RELATED [] is_a: CMO:0002434 ! plasma glutathione level is_a: CMO:0002437 ! blood oxidized glutathione level @@ -22036,7 +22036,7 @@ creation_date: 2014-06-05T12:22:49Z [Term] id: CMO:0002437 name: blood oxidized glutathione level -def: "The amount of oxidized glutathione (GSSG) in a specified sample of blood. GSSG is a molecule produced when glutathione is used as a reducing agent in a biochemical reaction, and consists of a pair of glutathione molecules connected by a disulfide bridge between their cysteine residues." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of oxidized glutathione (GSSG) in a specified sample of blood. GSSG is a molecule produced when glutathione is used as a reducing agent in a biochemical reaction, and consists of a pair of glutathione molecules connected by a disulfide bridge between their cysteine residues." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Glutathione] synonym: "blood GSSG level" RELATED [] is_a: CMO:0002432 ! blood glutathione level created_by: JSmith @@ -22045,7 +22045,7 @@ creation_date: 2014-06-05T12:22:49Z [Term] id: CMO:0002438 name: blood reduced glutathione level -def: "The amount of reduced glutathione (GSH) in a specified sample of blood. GSH is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. In GSH (as opposed to the oxidized form, GSSG) the thiol group on the cysteine is in its reduced form, that is, it contains a hydrogen atom and does not form a disulfide bridge with a second glutathione molecule." [Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of reduced glutathione (GSH) in a specified sample of blood. GSH is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. In GSH (as opposed to the oxidized form, GSSG) the thiol group on the cysteine is in its reduced form, that is, it contains a hydrogen atom and does not form a disulfide bridge with a second glutathione molecule." [https://en.wikipedia.org/wiki/Glutathione] synonym: "blood GSH level" RELATED [] is_a: CMO:0002432 ! blood glutathione level created_by: JSmith @@ -22054,7 +22054,7 @@ creation_date: 2014-06-05T12:31:48Z [Term] id: CMO:0002439 name: serum reduced glutathione level -def: "The amount of reduced glutathione (GSH) in a specified sample of serum. GSH is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. In GSH (as opposed to the oxidized form, GSSG) the thiol group on the cysteine is in its reduced form, that is, it contains a hydrogen atom and does not form a disulfide bridge with a second glutathione molecule." [Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of reduced glutathione (GSH) in a specified sample of serum. GSH is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. In GSH (as opposed to the oxidized form, GSSG) the thiol group on the cysteine is in its reduced form, that is, it contains a hydrogen atom and does not form a disulfide bridge with a second glutathione molecule." [https://en.wikipedia.org/wiki/Glutathione] synonym: "serum GSH level" RELATED [] is_a: CMO:0002433 ! serum glutathione level is_a: CMO:0002438 ! blood reduced glutathione level @@ -22064,7 +22064,7 @@ creation_date: 2014-06-05T12:39:39Z [Term] id: CMO:0002440 name: plasma reduced glutathione level -def: "The amount of reduced glutathione (GSH) in a specified sample of plasma. GSH is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. In GSH (as opposed to the oxidized form, GSSG) the thiol group on the cysteine is in its reduced form, that is, it contains a hydrogen atom and does not form a disulfide bridge with a second glutathione molecule." [Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of reduced glutathione (GSH) in a specified sample of plasma. GSH is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. In GSH (as opposed to the oxidized form, GSSG) the thiol group on the cysteine is in its reduced form, that is, it contains a hydrogen atom and does not form a disulfide bridge with a second glutathione molecule." [https://en.wikipedia.org/wiki/Glutathione] synonym: "plasma GSH level" RELATED [] is_a: CMO:0002434 ! plasma glutathione level is_a: CMO:0002438 ! blood reduced glutathione level @@ -22104,7 +22104,7 @@ creation_date: 2014-06-05T12:49:19Z [Term] id: CMO:0002444 name: blood superoxide dismutase activity level -def: "The amount of ezymatic activity of superoxide dismutase (SOD) in a specified sample of blood. SOD is a metalloprotein enzyme that catalyses the conversion of highly reactive superoxide radicals (O2-) to the less toxic products hydrogen peroxide (H2O2) and molecular oxygen (O2)." [Wikipedia:http\://en.wikipedia.org/wiki/Superoxide_dismutase] +def: "The amount of ezymatic activity of superoxide dismutase (SOD) in a specified sample of blood. SOD is a metalloprotein enzyme that catalyses the conversion of highly reactive superoxide radicals (O2-) to the less toxic products hydrogen peroxide (H2O2) and molecular oxygen (O2)." [https://en.wikipedia.org/wiki/Superoxide_dismutase] synonym: "blood SOD activity level" RELATED [] is_a: CMO:0000064 ! blood enzyme activity level created_by: JSmith @@ -22113,7 +22113,7 @@ creation_date: 2014-06-05T12:53:36Z [Term] id: CMO:0002445 name: serum superoxide dismutase activity level -def: "The amount of ezymatic activity of superoxide dismutase (SOD) in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. SOD is a metalloprotein enzyme that catalyses the conversion of highly reactive superoxide radicals (O2-) to the less toxic products hydrogen peroxide (H2O2) and molecular oxygen (O2)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Superoxide_dismutase] +def: "The amount of ezymatic activity of superoxide dismutase (SOD) in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. SOD is a metalloprotein enzyme that catalyses the conversion of highly reactive superoxide radicals (O2-) to the less toxic products hydrogen peroxide (H2O2) and molecular oxygen (O2)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Superoxide_dismutase] synonym: "serum SOD activity level" RELATED [] is_a: CMO:0002444 ! blood superoxide dismutase activity level created_by: JSmith @@ -22122,7 +22122,7 @@ creation_date: 2014-06-05T12:55:18Z [Term] id: CMO:0002446 name: plasma superoxide dismutase activity level -def: "The amount of ezymatic activity of superoxide dismutase (SOD) in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. SOD is a metalloprotein enzyme that catalyses the conversion of highly reactive superoxide radicals (O2-) to the less toxic products hydrogen peroxide (H2O2) and molecular oxygen (O2)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Superoxide_dismutase] +def: "The amount of ezymatic activity of superoxide dismutase (SOD) in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. SOD is a metalloprotein enzyme that catalyses the conversion of highly reactive superoxide radicals (O2-) to the less toxic products hydrogen peroxide (H2O2) and molecular oxygen (O2)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Superoxide_dismutase] synonym: "plasma SOD activity level" RELATED [] is_a: CMO:0002444 ! blood superoxide dismutase activity level created_by: JSmith @@ -22131,7 +22131,7 @@ creation_date: 2014-06-05T12:55:22Z [Term] id: CMO:0002447 name: blood malondialdehyde level -def: "The amount of malondialdehyde in a specified sample of blood. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress and lipid peroxidation. Malondialdehyde is the substrate for the TBARS (thiobarbituric acid reactive substances) assay." [Wikipedia:http\://en.wikipedia.org/wiki/Malondialdehyde] +def: "The amount of malondialdehyde in a specified sample of blood. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress and lipid peroxidation. Malondialdehyde is the substrate for the TBARS (thiobarbituric acid reactive substances) assay." [https://en.wikipedia.org/wiki/Malondialdehyde] synonym: "blood lipid peroxide level" EXACT [] synonym: "blood MDA level" EXACT [] synonym: "blood thiobarbituric acid-reactive substance level" EXACT [] @@ -22142,7 +22142,7 @@ creation_date: 2014-06-05T12:58:25Z [Term] id: CMO:0002448 name: plasma malondialdehyde level -def: "The amount of malondialdehyde in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress. Malondialdehyde is the substrate for the TBARS (thiobarbituric acid reactive substances) assay of lipid peroxidation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Malondialdehyde] +def: "The amount of malondialdehyde in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress. Malondialdehyde is the substrate for the TBARS (thiobarbituric acid reactive substances) assay of lipid peroxidation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Malondialdehyde] synonym: "plasma lipid peroxide level" EXACT [] synonym: "plasma MDA level" EXACT [] synonym: "plasma thiobarbituric acid-reactive substance level" EXACT [] @@ -22153,7 +22153,7 @@ creation_date: 2014-06-05T12:59:57Z [Term] id: CMO:0002449 name: serum malondialdehyde level -def: "The amount of malondialdehyde in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress. Malondialdehyde is the substrate for the TBARS (thiobarbituric acid reactive substances) assay of lipid peroxidation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Malondialdehyde] +def: "The amount of malondialdehyde in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress. Malondialdehyde is the substrate for the TBARS (thiobarbituric acid reactive substances) assay of lipid peroxidation." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Malondialdehyde] synonym: "serum lipid peroxide level" EXACT [] synonym: "serum MDA level" EXACT [] synonym: "serum thiobarbituric acid-reactive substance level" EXACT [] @@ -22174,7 +22174,7 @@ creation_date: 2014-06-05T13:03:29Z [Term] id: CMO:0002451 name: liver malondialdehyde level -def: "The amount of malondialdehyde in a specified sample of liver tissue. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress." [Wikipedia:http\://en.wikipedia.org/wiki/Malondialdehyde] +def: "The amount of malondialdehyde in a specified sample of liver tissue. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress." [https://en.wikipedia.org/wiki/Malondialdehyde] synonym: "hepatic malondialdehyde level" RELATED [] synonym: "liver propanedial level" RELATED [] xref: CHEBI:566274 @@ -22281,7 +22281,7 @@ creation_date: 2014-06-09T18:11:50Z [Term] id: CMO:0002462 name: concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (EC50) -def: "A calculated value for the concentration of potassium chloride (KCl) at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of KCl is halfway between the baseline value and the highest achievable value of such KCl-induced contractile energy. Potassium chloride is the salt of the potassium cation (K+) and the chlorine/chloride anion (Cl-). It is used as an eletroylyte replenisher and has mild vasoconstrictive properties when applied directly to blood vessels." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, PMID:22031779, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for the concentration of potassium chloride (KCl) at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of KCl is halfway between the baseline value and the highest achievable value of such KCl-induced contractile energy. Potassium chloride is the salt of the potassium cation (K+) and the chlorine/chloride anion (Cl-). It is used as an eletroylyte replenisher and has mild vasoconstrictive properties when applied directly to blood vessels." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, PMID:22031779, https://en.wikipedia.org/wiki/EC50] synonym: "KCl half maximal effective concentration (EC50)" RELATED [] synonym: "potassium chloride half maximal effective concentration (EC50)" EXACT [] xref: CHEBI:32588 @@ -22293,7 +22293,7 @@ creation_date: 2014-06-09T18:19:26Z [Term] id: CMO:0002463 name: logarithm of the concentration of potassium chloride at which the force of blood vessel contraction is half the maximum value (Log EC50) -def: "A calculated value for logarithm of the concentration of potassium chloride (KCl) at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of KCl is halfway between the baseline value and the highest achievable value of such KCl-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value." [CHEBI:8093, Collins:Collins_Online_English_Dictionary, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for logarithm of the concentration of potassium chloride (KCl) at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of KCl is halfway between the baseline value and the highest achievable value of such KCl-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value." [CHEBI:8093, Collins:Collins_Online_English_Dictionary, https://en.wikipedia.org/wiki/EC50] synonym: "KCl Log half maximal effective concentration (Log EC50)" RELATED [] synonym: "potassium chloride Log half maximal effective concentration (Log EC50)" EXACT [] xref: CHEBI:32588 @@ -22305,7 +22305,7 @@ creation_date: 2014-06-09T18:28:02Z [Term] id: CMO:0002464 name: concentration of vasoconstrictor at which the force of blood vessel contraction is half the maximum value (EC50) -def: "A calculated value for the concentration of a vasoconstrictor at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of the stimulus is halfway between the baseline value and the highest achievable value of such stimulus-induced contractile energy. A vasoconstrictor is any agent or condition that narrows blood vessels by constricting the smooth muscle in the vessel walls." [Farlex:Farlex_Partner_Medical_Dictionary_2012, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for the concentration of a vasoconstrictor at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of the stimulus is halfway between the baseline value and the highest achievable value of such stimulus-induced contractile energy. A vasoconstrictor is any agent or condition that narrows blood vessels by constricting the smooth muscle in the vessel walls." [Farlex:Farlex_Partner_Medical_Dictionary_2012, https://en.wikipedia.org/wiki/EC50] synonym: "vasoconstrictor half maximal effective concentration (EC50)" EXACT [] is_a: CMO:0000720 ! calculated blood vessel contractile force measurement created_by: JSmith @@ -22314,7 +22314,7 @@ creation_date: 2014-06-09T18:33:14Z [Term] id: CMO:0002465 name: logarithm of the concentration of vasoconstrictor at which the force of blood vessel contraction is half the maximum value (Log EC50) -def: "A calculated value for logarithm of the concentration of a vasoconstrictor at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of the stimulus is halfway between the baseline value and the highest achievable value of such stimulus-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value. A vasoconstrictor is any agent or condition that narrows blood vessels by constricting the smooth muscle in the vessel walls." [Collins:Collins_Online_English_Dictionary, Farlex:Farlex_Partner_Medical_Dictionary_2012, Wikipedia:http\://en.wikipedia.org/wiki/EC50] +def: "A calculated value for logarithm of the concentration of a vasoconstrictor at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of the stimulus is halfway between the baseline value and the highest achievable value of such stimulus-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value. A vasoconstrictor is any agent or condition that narrows blood vessels by constricting the smooth muscle in the vessel walls." [Collins:Collins_Online_English_Dictionary, Farlex:Farlex_Partner_Medical_Dictionary_2012, https://en.wikipedia.org/wiki/EC50] synonym: "vasoconstrictor Log half maximal effective concentration (Log EC50)" EXACT [] is_a: CMO:0000720 ! calculated blood vessel contractile force measurement created_by: JSmith @@ -22372,7 +22372,7 @@ creation_date: 2014-06-12T12:40:26Z [Term] id: CMO:0002471 name: blood paracetamol level area under curve (AUC) -def: "A calculated measurement in which a series of measurements of the amount of paracetamol (also known as acetaminophen) in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Wikipedia:http\://en.wikipedia.org/wiki/Area_under_curve] +def: "A calculated measurement in which a series of measurements of the amount of paracetamol (also known as acetaminophen) in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [https://en.wikipedia.org/wiki/Area_under_curve] synonym: "blood acetaminofen AUC" RELATED [] synonym: "blood acetaminofen level area under curve" EXACT [] xref: CHEBI:46195 @@ -22394,7 +22394,7 @@ creation_date: 2014-06-12T12:46:58Z [Term] id: CMO:0002473 name: plasma paracetamol level area under curve (AUC) -def: "A calculated measurement in which a series of measurements of the amount of paracetamol (also known as acetaminophen) in a specified volume of plasma is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Wikipedia:http\://en.wikipedia.org/wiki/Area_under_curve] +def: "A calculated measurement in which a series of measurements of the amount of paracetamol (also known as acetaminophen) in a specified volume of plasma is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [https://en.wikipedia.org/wiki/Area_under_curve] synonym: "plasma acetaminophen AUC" RELATED [] synonym: "plasma acetaminophen level area under curve" EXACT [] xref: CHEBI:46195 @@ -22406,7 +22406,7 @@ creation_date: 2014-06-12T12:48:31Z [Term] id: CMO:0002474 name: blood glutamate dehydrogenase activity level -def: "Measurement of the amount of ezymatic activity of glutamate dehydrogenase, the enzyme which catalyzes the interconversion of glutamate and alpha-ketoglutarate (ie, the reversible conversion of glutamic acid to 2-oxoglutaric acid and ammonia), in a specified sample of blood." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Alpha-Ketoglutaric_acid] +def: "Measurement of the amount of ezymatic activity of glutamate dehydrogenase, the enzyme which catalyzes the interconversion of glutamate and alpha-ketoglutarate (ie, the reversible conversion of glutamic acid to 2-oxoglutaric acid and ammonia), in a specified sample of blood." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Alpha-Ketoglutaric_acid] synonym: "blood GD activity level" RELATED [] synonym: "blood GLDH activity level" RELATED [] is_a: CMO:0000064 ! blood enzyme activity level @@ -22416,7 +22416,7 @@ creation_date: 2014-06-12T13:05:15Z [Term] id: CMO:0002475 name: serum glutamate dehydrogenase activity level -def: "Measurement of the amount of ezymatic activity of glutamate dehydrogenase, the enzyme which catalyzes the interconversion of glutamate and alpha-ketoglutarate (ie, the reversible conversion of glutamic acid to 2-oxoglutaric acid and ammonia), in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Alpha-Ketoglutaric_acid] +def: "Measurement of the amount of ezymatic activity of glutamate dehydrogenase, the enzyme which catalyzes the interconversion of glutamate and alpha-ketoglutarate (ie, the reversible conversion of glutamic acid to 2-oxoglutaric acid and ammonia), in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Alpha-Ketoglutaric_acid] synonym: "serum GD activity level" RELATED [] synonym: "serum GLDH activity level" RELATED [] is_a: CMO:0002474 ! blood glutamate dehydrogenase activity level @@ -22426,7 +22426,7 @@ creation_date: 2014-06-12T13:08:23Z [Term] id: CMO:0002476 name: plasma glutamate dehydrogenase activity level -def: "Measurement of the amount of ezymatic activity of glutamate dehydrogenase, the enzyme which catalyzes the interconversion of glutamate and alpha-ketoglutarate (ie, the reversible conversion of glutamic acid to 2-oxoglutaric acid and ammonia), in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Alpha-Ketoglutaric_acid] +def: "Measurement of the amount of ezymatic activity of glutamate dehydrogenase, the enzyme which catalyzes the interconversion of glutamate and alpha-ketoglutarate (ie, the reversible conversion of glutamic acid to 2-oxoglutaric acid and ammonia), in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Alpha-Ketoglutaric_acid] synonym: "plasma GD activity level" RELATED [] synonym: "plasma GLDH activity level" RELATED [] is_a: CMO:0002474 ! blood glutamate dehydrogenase activity level @@ -22467,7 +22467,7 @@ creation_date: 2014-06-12T13:51:09Z [Term] id: CMO:0002480 name: liver glutathione level -def: "The amount of glutathione in a specified sample of liver tissue. Glutathione (GSH/GSSG) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "The amount of glutathione in a specified sample of liver tissue. Glutathione (GSH/GSSG) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [https://en.wikipedia.org/wiki/Glutathione] synonym: "hepatic glutathione level" RELATED [] synonym: "liver GSH level" RELATED [] xref: CHEBI:16856 @@ -22478,7 +22478,7 @@ creation_date: 2014-06-12T13:56:12Z [Term] id: CMO:0002481 name: calculated liver glutathione level -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of glutathione in a specified sample of liver tissue. Glutathione (GSH/GSSG) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of glutathione in a specified sample of liver tissue. Glutathione (GSH/GSSG) is an antioxidant tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Glutathione] synonym: "calculated hepatic glutathione level" RELATED [] synonym: "calculated liver GSH level" RELATED [] xref: CHEBI:16856 @@ -22489,7 +22489,7 @@ creation_date: 2014-06-12T13:59:32Z [Term] id: CMO:0002482 name: liver oxidized glutathione level to liver weight ratio -def: "A calculated measurement in which the amount of oxidized glutathione in a specified sample of liver is divided by the total weight of that liver, and the result presented as a ratio, fraction, quotient or percentage. Oxidized glutathione (GSSG) is a glutathione peptide in which the sulfhydryl/thiol group (-SH) of the cysteine has donated its proton (-H) and formed a disulfide bridge (R-S-S-R) with a second glutathione molecule." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "A calculated measurement in which the amount of oxidized glutathione in a specified sample of liver is divided by the total weight of that liver, and the result presented as a ratio, fraction, quotient or percentage. Oxidized glutathione (GSSG) is a glutathione peptide in which the sulfhydryl/thiol group (-SH) of the cysteine has donated its proton (-H) and formed a disulfide bridge (R-S-S-R) with a second glutathione molecule." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Glutathione] synonym: "liver glutathione disulfide level to liver weight ratio" EXACT [] synonym: "liver GSSG level to liver weight ratio" RELATED [] synonym: "ratio of hepatic oxidized glutathione level to liver weight" RELATED [] @@ -22501,7 +22501,7 @@ creation_date: 2014-06-12T14:02:10Z [Term] id: CMO:0002483 name: liver reduced glutathione level to liver weight ratio -def: "A calculated measurement in which the amount of reduced glutathione in a specified sample of liver is divided by the total weight of that liver, and the result presented as a ratio, fraction, quotient or percentage. Reduced glutathione is a glutathione peptide in which the sulfhydryl/thiol group (-SH) of the cysteine exists in its reduced form, rather than as part of a disulfide bridge with a second glutathione molecule." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Glutathione] +def: "A calculated measurement in which the amount of reduced glutathione in a specified sample of liver is divided by the total weight of that liver, and the result presented as a ratio, fraction, quotient or percentage. Reduced glutathione is a glutathione peptide in which the sulfhydryl/thiol group (-SH) of the cysteine exists in its reduced form, rather than as part of a disulfide bridge with a second glutathione molecule." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Glutathione] synonym: "liver GSH level to liver weight ratio" RELATED [] synonym: "ratio of hepatic reduced glutathione level to liver weight" RELATED [] xref: CHEBI:16856 @@ -22512,7 +22512,7 @@ creation_date: 2014-06-12T14:25:10Z [Term] id: CMO:0002484 name: calculated liver malondialdehyde level -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of malondialdehyde in a specified sample of liver tissue. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Malondialdehyde] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the amount of malondialdehyde in a specified sample of liver tissue. Malondialdehyde is an organic compound with the formula CH2(CHO)2. It is a reactive species which occurs naturally, is generally found in the enol form (HOCH=CH-CHO), and is a marker for oxidative stress." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, https://en.wikipedia.org/wiki/Malondialdehyde] synonym: "calculated hepatic malondialdehyde level" RELATED [] synonym: "calculated liver propanedial level" RELATED [] xref: CHEBI:566274 @@ -22684,7 +22684,7 @@ creation_date: 2014-07-01T11:15:11Z [Term] id: CMO:0002503 name: E wave velocity -def: "Measurement of the speed at which blood flows into the ventricle during passive filling, that is, during the period when the blood flows from the atrium to the ventricle due to gravity rather than as a result of active contraction of the atrium." [Website:http\://www.ncbi.nlm.nih.gov/books/NBK2215/, Wikipedia:http\://en.wikipedia.org/wiki/E/A_ratio] +def: "Measurement of the speed at which blood flows into the ventricle during passive filling, that is, during the period when the blood flows from the atrium to the ventricle due to gravity rather than as a result of active contraction of the atrium." [http://www.ncbi.nlm.nih.gov/books/NBK2215/, https://en.wikipedia.org/wiki/E/A_ratio] is_a: CMO:0002502 ! heart blood flow measurement created_by: JSmith creation_date: 2014-07-01T11:21:13Z @@ -22692,7 +22692,7 @@ creation_date: 2014-07-01T11:21:13Z [Term] id: CMO:0002504 name: E wave deceleration time -def: "An echocardiographic measurement of the amount of time between the maximum 'E point', that is, the maximum velocity of passive blood flow from the atrium to the ventricle, and the return to baseline at the end of early mitral flow." [Website:http\://eknygos.lsmuni.lt/springer/641/119-131.pdf, Wikipedia:http\://en.wikipedia.org/wiki/E/A_ratio] +def: "An echocardiographic measurement of the amount of time between the maximum 'E point', that is, the maximum velocity of passive blood flow from the atrium to the ventricle, and the return to baseline at the end of early mitral flow." [http://eknygos.lsmuni.lt/springer/641/119-131.pdf, https://en.wikipedia.org/wiki/E/A_ratio] synonym: "DT" RELATED [] synonym: "EDT" RELATED [] is_a: CMO:0002502 ! heart blood flow measurement @@ -22702,7 +22702,7 @@ creation_date: 2014-07-01T11:23:06Z [Term] id: CMO:0002505 name: E wave deceleration rate -def: "Measurement of the decrease in transmitral blood flow velocity per unit time or the rate at which the velocity of passive blood flow from the atrium to the ventricle decreases over time as the ventricle fills and the atrium empties, calculated as the slope of transmitral velocity vs time." [PMID:17588719, Website:http\://123sonography.com/node/943, Wikipedia:http\://en.wikipedia.org/wiki/E/A_ratio] +def: "Measurement of the decrease in transmitral blood flow velocity per unit time or the rate at which the velocity of passive blood flow from the atrium to the ventricle decreases over time as the ventricle fills and the atrium empties, calculated as the slope of transmitral velocity vs time." [PMID:17588719, http://123sonography.com/node/943, https://en.wikipedia.org/wiki/E/A_ratio] synonym: "EDR" RELATED [] is_a: CMO:0002502 ! heart blood flow measurement created_by: JSmith @@ -22794,7 +22794,7 @@ creation_date: 2014-07-28T18:01:07Z [Term] id: CMO:0002516 name: white blood cell radioactive nucleoside incorporation -def: "Measurement of the amount of a radioactive nucleoside, such as tritiated (3H-) thymidine, incorporated into white blood cells during a specified period of time. The level of nucleoside incorporation is proportional to the amount of cell proliferation and is used as a measure of the latter." [Website:http\://www.lifetechnologies.com/us/en/home/references/protocols/cell-and-tissue-analysis/cell-profilteration-assay-protocols/angiogenesis-protocols/thymidine-incorporation-assay.html, Wikipedia:http\://en.wikipedia.org/wiki/Thymidine] +def: "Measurement of the amount of a radioactive nucleoside, such as tritiated (3H-) thymidine, incorporated into white blood cells during a specified period of time. The level of nucleoside incorporation is proportional to the amount of cell proliferation and is used as a measure of the latter." [http://www.lifetechnologies.com/us/en/home/references/protocols/cell-and-tissue-analysis/cell-profilteration-assay-protocols/angiogenesis-protocols/thymidine-incorporation-assay.html, https://en.wikipedia.org/wiki/Thymidine] synonym: "white blood cell DNA synthesis measurement" RELATED [] synonym: "white blood cell level of radioactive nucleoside incorporation" EXACT [] synonym: "white blood cell proliferation measurement" RELATED [] @@ -22805,7 +22805,7 @@ creation_date: 2014-08-04T14:38:43Z [Term] id: CMO:0002517 name: absolute change in antibody titer -def: "The difference in antibody titer between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in antibody titer between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed \nto a dissimilarity of two values expressed as a ratio or as a percentage. In this context it \nis not intended to necessarily imply the difference expressed as an absolute value |n|, that \nis, the numeric value of the difference without regard to its sign. synonym: "antibody response" RELATED [] is_a: CMO:0002549 ! change in antibody titer @@ -22815,7 +22815,7 @@ creation_date: 2014-08-04T15:16:45Z [Term] id: CMO:0002518 name: absolute change in the logarithm of the antibody titer -def: "The difference in the logarithm of the antibody titer between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. A logarithm is the power to which a base, such as 10, must be raised to produce a given number." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in the logarithm of the antibody titer between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity. A logarithm is the power to which a base, such as 10, must be raised to produce a given number." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed \nto a dissimilarity of two values expressed as a ratio or as a percentage. In this context it \nis not intended to necessarily imply the difference expressed as an absolute value |n|, that \nis, the numeric value of the difference without regard to its sign. synonym: "change in Log(Ab titer)" RELATED [] synonym: "Log antibody response" RELATED [] @@ -22869,7 +22869,7 @@ creation_date: 2014-08-04T16:26:53Z [Term] id: CMO:0002524 name: superovulation/artificial insemination measurement -def: "Any measurement having to do with the artificial stimulation of ovulation, that is, the planned production of a greater than normal number of ova in an individual female during a single ovulation period, and/or the introduction of sperm into the female reproductive tract through means other than normal sexual intercourse." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Artificial_insemination] +def: "Any measurement having to do with the artificial stimulation of ovulation, that is, the planned production of a greater than normal number of ova in an individual female during a single ovulation period, and/or the introduction of sperm into the female reproductive tract through means other than normal sexual intercourse." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://en.wikipedia.org/wiki/Artificial_insemination] synonym: "ovarian hyperstimulation/artificial insemination measurement" RELATED [] synonym: "SO/AI measurement" RELATED [] is_a: CMO:0000389 ! reproduction measurement @@ -22879,7 +22879,7 @@ creation_date: 2014-08-05T13:44:12Z [Term] id: CMO:0002525 name: number of degenerate embryos per superovulation/artificial insemination event -def: "The number of embryos produced in the process of a single round of superovulation and artificial insemination that have degenerated and are not likely to be viable or to produce offspring if transfered to a recipient." [Website:http\://www.merckmanuals.com/vet/management_and_nutrition/embryo_transfer_in_farm_animals/embryo_transfer_in_cattle.html] +def: "The number of embryos produced in the process of a single round of superovulation and artificial insemination that have degenerated and are not likely to be viable or to produce offspring if transfered to a recipient." [http://www.merckmanuals.com/vet/management_and_nutrition/embryo_transfer_in_farm_animals/embryo_transfer_in_cattle.html] synonym: "number of degenerated embryos per round of SO/AI" RELATED [] is_a: CMO:0002524 ! superovulation/artificial insemination measurement created_by: JSMITH @@ -22888,7 +22888,7 @@ creation_date: 2014-08-05T14:13:53Z [Term] id: CMO:0002526 name: number of transferable embryos per superovulation/artificial insemination event -def: "The number of embryos produced in the process of a single round of superovulation and artificial insemination that are of sufficient quality to transfer from the donor female to a recipient female with a reasonable expectation of producing viable offspring." [Website:http\://www.merckmanuals.com/vet/management_and_nutrition/embryo_transfer_in_farm_animals/embryo_transfer_in_cattle.html] +def: "The number of embryos produced in the process of a single round of superovulation and artificial insemination that are of sufficient quality to transfer from the donor female to a recipient female with a reasonable expectation of producing viable offspring." [http://www.merckmanuals.com/vet/management_and_nutrition/embryo_transfer_in_farm_animals/embryo_transfer_in_cattle.html] synonym: "number of transferable embryos per round of SO/AI" RELATED [] is_a: CMO:0002524 ! superovulation/artificial insemination measurement created_by: JSMITH @@ -22897,7 +22897,7 @@ creation_date: 2014-08-05T14:33:22Z [Term] id: CMO:0002527 name: number of unfertilized ova per superovulation/artificial insemination event -def: "The number of female gametes, recovered from a donor following a single round of superovulation and artificial insemination, that did not undergo fertilization, that is, the union of male and female gametes to form the diploid zygote, leading to development of a new individual." [Website:http\://www.merckmanuals.com/vet/management_and_nutrition/embryo_transfer_in_farm_animals/embryo_transfer_in_cattle.html] +def: "The number of female gametes, recovered from a donor following a single round of superovulation and artificial insemination, that did not undergo fertilization, that is, the union of male and female gametes to form the diploid zygote, leading to development of a new individual." [http://www.merckmanuals.com/vet/management_and_nutrition/embryo_transfer_in_farm_animals/embryo_transfer_in_cattle.html] synonym: "number of unfertilized eggs recovered per round of SO/AI" RELATED [] is_a: CMO:0002524 ! superovulation/artificial insemination measurement created_by: JSMITH @@ -22906,7 +22906,7 @@ creation_date: 2014-08-05T14:40:37Z [Term] id: CMO:0002528 name: total number of ova per superovulation/artificial insemination event -def: "A count of the total number of female gametes, regardless of final status or quality, produced in a donor female during a single round of superovulation and artificial insemination." [Website:http\://www.merckmanuals.com/vet/management_and_nutrition/embryo_transfer_in_farm_animals/embryo_transfer_in_cattle.html] +def: "A count of the total number of female gametes, regardless of final status or quality, produced in a donor female during a single round of superovulation and artificial insemination." [http://www.merckmanuals.com/vet/management_and_nutrition/embryo_transfer_in_farm_animals/embryo_transfer_in_cattle.html] is_a: CMO:0002524 ! superovulation/artificial insemination measurement created_by: JSMITH creation_date: 2014-08-05T14:41:44Z @@ -22914,7 +22914,7 @@ creation_date: 2014-08-05T14:41:44Z [Term] id: CMO:0002529 name: blood tyrosinase activity level -def: "Quantitation of the catalytic effect exerted by tyrosinase (Tyr) in a specified sample of blood. Tyr is a copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. Tyr is the rate-limiting enzyme for controlling the production of melanin." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Tyrosinase] +def: "Quantitation of the catalytic effect exerted by tyrosinase (Tyr) in a specified sample of blood. Tyr is a copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. Tyr is the rate-limiting enzyme for controlling the production of melanin." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, https://en.wikipedia.org/wiki/Tyrosinase] is_a: CMO:0000064 ! blood enzyme activity level created_by: JSMITH creation_date: 2014-08-05T15:42:48Z @@ -22922,7 +22922,7 @@ creation_date: 2014-08-05T15:42:48Z [Term] id: CMO:0002530 name: serum tyrosinase activity level -def: "Quantitation of the catalytic effect exerted by tyrosinase (Tyr) in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Tyr is a copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. Tyr is the rate-limiting enzyme for controlling the production of melanin." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Tyrosinase] +def: "Quantitation of the catalytic effect exerted by tyrosinase (Tyr) in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Tyr is a copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. Tyr is the rate-limiting enzyme for controlling the production of melanin." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Tyrosinase] is_a: CMO:0002529 ! blood tyrosinase activity level created_by: JSMITH creation_date: 2014-08-05T15:43:48Z @@ -22930,7 +22930,7 @@ creation_date: 2014-08-05T15:43:48Z [Term] id: CMO:0002531 name: plasma tyrosinase activity level -def: "Quantitation of the catalytic effect exerted by tyrosinase (Tyr) in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Tyr is a copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. Tyr is the rate-limiting enzyme for controlling the production of melanin." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Tyrosinase] +def: "Quantitation of the catalytic effect exerted by tyrosinase (Tyr) in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Tyr is a copper-containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. Tyr is the rate-limiting enzyme for controlling the production of melanin." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Tyrosinase] is_a: CMO:0002529 ! blood tyrosinase activity level created_by: JSMITH creation_date: 2014-08-05T15:47:22Z @@ -22990,7 +22990,7 @@ creation_date: 2014-08-05T17:36:28Z [Term] id: CMO:0002538 name: absolute change in hematocrit -def: "The difference in hematocrit (the percentage of total blood volume that is made up of red blood cells) between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The difference in hematocrit (the percentage of total blood volume that is made up of red blood cells) between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in packed cell volume" RELATED [] synonym: "absolute change in packed red blood cell volume" RELATED [] @@ -23002,7 +23002,7 @@ creation_date: 2014-08-05T17:44:34Z [Term] id: CMO:0002539 name: percent change in hematocrit -def: "A calculated measurement of the relative difference in hematocrit (the percentage of total blood volume that is made up of red blood cells) between a treated state and a control state or between two points in time, expressed as a percentage." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Percent_change] +def: "A calculated measurement of the relative difference in hematocrit (the percentage of total blood volume that is made up of red blood cells) between a treated state and a control state or between two points in time, expressed as a percentage." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, https://en.wikipedia.org/wiki/Percent_change] synonym: "% change in Hct" RELATED [] synonym: "percent change in packed cell volume" RELATED [] synonym: "percent change in packed red blood cell volume" RELATED [] @@ -23013,7 +23013,7 @@ creation_date: 2014-08-05T17:48:03Z [Term] id: CMO:0002540 name: left ventricular isovolumetric relaxation time -def: "The length of time in the cardiac cycle between the end of left ventricular relaxation and the start of left ventricular filling. This represents the time in the cardiac cycle between closure of the aortic valve and opening of the mitral valve." [Mondofacto:Mondofacto_Online_Medical_Dictionary, Website:http\://123sonography.com/node/943] +def: "The length of time in the cardiac cycle between the end of left ventricular relaxation and the start of left ventricular filling. This represents the time in the cardiac cycle between closure of the aortic valve and opening of the mitral valve." [Mondofacto:Mondofacto_Online_Medical_Dictionary, http://123sonography.com/node/943] synonym: "LV-IVRT" RELATED [] synonym: "time constant of isovolumetric LV fall" EXACT [] is_a: CMO:0001482 ! heart isovolumetric relaxation time @@ -23023,7 +23023,7 @@ creation_date: 2014-08-06T10:31:27Z [Term] id: CMO:0002541 name: left ventricular isovolumetric contraction time -def: "The time interval from the completion of the mitral valve closure to the beginning of the aortic valve opening, that is, the period of contraction during which both the mitral and aortic valves are closed so that the volume of the ventricular space doesn't change." [PMID:7464080, Wikipedia:http\://en.wikipedia.org/wiki/Isovolumetric_contraction] +def: "The time interval from the completion of the mitral valve closure to the beginning of the aortic valve opening, that is, the period of contraction during which both the mitral and aortic valves are closed so that the volume of the ventricular space doesn't change." [PMID:7464080, https://en.wikipedia.org/wiki/Isovolumetric_contraction] is_a: CMO:0000981 ! ventricle contraction measurement created_by: JSMITH creation_date: 2014-08-06T10:46:35Z @@ -23047,7 +23047,7 @@ creation_date: 2014-08-08T13:30:34Z [Term] id: CMO:0002544 name: fecal parasite egg count -def: "The enumeration, i.e. measurement of the total number of parasite eggs present in a specified sample of host feces, the usually solid waste matter discharged from the digestive tract after food has been digested. In parasitology, eggs are fertilized gametes, especially of species such as nematodes, which through further development give rise to larvae and then adult parasites. Parasite eggs are distinguished from oocysts by the lack of a thick encapsulating cyst wall." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Website:https\://www.aasv.org/shap/issues/v5n2/v5n2p67.pdf] +def: "The enumeration, i.e. measurement of the total number of parasite eggs present in a specified sample of host feces, the usually solid waste matter discharged from the digestive tract after food has been digested. In parasitology, eggs are fertilized gametes, especially of species such as nematodes, which through further development give rise to larvae and then adult parasites. Parasite eggs are distinguished from oocysts by the lack of a thick encapsulating cyst wall." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://www.aasv.org/shap/issues/v5n2/v5n2p67.pdf] synonym: "faecal parasite egg count" EXACT [] is_a: CMO:0002543 ! parasite egg/oocyst count created_by: JSMITH @@ -23074,7 +23074,7 @@ creation_date: 2014-08-08T16:56:30Z [Term] id: CMO:0002547 name: basal white blood cell radioactive nucleoside incorporation -def: "Measurement of the unstimulated, baseline or lowest possible amount of a radioactive nucleoside, such as tritiated (3H-) thymidine, incorporated into white blood cells during a specified period of time. The level of nucleoside incorporation is proportional to the amount of cell proliferation and is used as a measure of the latter." [Website:http\://www.lifetechnologies.com/us/en/home/references/protocols/cell-and-tissue-analysis/cell-profilteration-assay-protocols/angiogenesis-protocols/thymidine-incorporation-assay.html, Wikipedia:http\://en.wikipedia.org/wiki/Thymidine] +def: "Measurement of the unstimulated, baseline or lowest possible amount of a radioactive nucleoside, such as tritiated (3H-) thymidine, incorporated into white blood cells during a specified period of time. The level of nucleoside incorporation is proportional to the amount of cell proliferation and is used as a measure of the latter." [http://www.lifetechnologies.com/us/en/home/references/protocols/cell-and-tissue-analysis/cell-profilteration-assay-protocols/angiogenesis-protocols/thymidine-incorporation-assay.html, https://en.wikipedia.org/wiki/Thymidine] synonym: "basal white blood cell DNA synthesis measurement" RELATED [] synonym: "basal white blood cell proliferation measurement" RELATED [] synonym: "baseline white blood cell radioactive nucleoside incorporation" RELATED [] @@ -23087,7 +23087,7 @@ creation_date: 2014-08-08T17:30:23Z [Term] id: CMO:0002548 name: mitogen-stimulated white blood cell radioactive nucleoside incorporation -def: "Measurement of the amount of a radioactive nucleoside, such as tritiated (3H-) thymidine, incorporated into white blood cells during a specified period of time following treatment with a substance that induces mitosis resulting in increased cell proliferation. The level of nucleoside incorporation is proportional to the amount of cell proliferation and is used as a measure of the latter." [Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Website:http\://www.lifetechnologies.com/us/en/home/references/protocols/cell-and-tissue-analysis/cell-profilteration-assay-protocols/angiogenesis-protocols/thymidine-incorporation-assay.html, Wikipedia:http\://en.wikipedia.org/wiki/Thymidine] +def: "Measurement of the amount of a radioactive nucleoside, such as tritiated (3H-) thymidine, incorporated into white blood cells during a specified period of time following treatment with a substance that induces mitosis resulting in increased cell proliferation. The level of nucleoside incorporation is proportional to the amount of cell proliferation and is used as a measure of the latter." [Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, http://www.lifetechnologies.com/us/en/home/references/protocols/cell-and-tissue-analysis/cell-profilteration-assay-protocols/angiogenesis-protocols/thymidine-incorporation-assay.html, https://en.wikipedia.org/wiki/Thymidine] synonym: "mitogen-stimulated white blood cell DNA synthesis measurement" RELATED [] synonym: "mitogen-stimulated white blood cell proliferation measurement" RELATED [] synonym: "white blood cell mitogen-stimulated level of radioactive nucleoside incorporation" EXACT [] @@ -23107,7 +23107,7 @@ creation_date: 2014-08-11T15:04:37Z [Term] id: CMO:0002550 name: percent change in antibody titer -def: "A calculated measurement of the relative difference in antibody titer between a treated state and a control state or between two points in time, expressed as a percentage." [Collins:Collins_Online_English_Dictionary, Wikipedia:http\://en.wikipedia.org/wiki/Percent_change] +def: "A calculated measurement of the relative difference in antibody titer between a treated state and a control state or between two points in time, expressed as a percentage." [Collins:Collins_Online_English_Dictionary, https://en.wikipedia.org/wiki/Percent_change] synonym: "relative change in antibody titer" RELATED [] is_a: CMO:0002549 ! change in antibody titer created_by: JSMITH @@ -23116,7 +23116,7 @@ creation_date: 2014-08-11T15:07:21Z [Term] id: CMO:0002551 name: right ventricular isovolumetric relaxation time -def: "The length of time in the cardiac cycle between the end of right ventricular relaxation and the start of right ventricular filling." [Mondofacto:Mondofacto_Online_Medical_Dictionary, Website:http\://123sonography.com/node/943] +def: "The length of time in the cardiac cycle between the end of right ventricular relaxation and the start of right ventricular filling." [Mondofacto:Mondofacto_Online_Medical_Dictionary, http://123sonography.com/node/943] synonym: "RV-IVRT" RELATED [] is_a: CMO:0001482 ! heart isovolumetric relaxation time created_by: JSMITH @@ -23125,7 +23125,7 @@ creation_date: 2014-08-18T11:44:51Z [Term] id: CMO:0002552 name: calculated left ventricular isovolumetric relaxation time -def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the length of time in the cardiac cycle between the end of left ventricular relaxation and the start of left ventricular filling." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Mondofacto:Mondofacto_Online_Medical_Dictionary, Website:http\://123sonography.com/node/943] +def: "A measurement which has been normalized, adjusted or derived by a mathematical process or computation, of the length of time in the cardiac cycle between the end of left ventricular relaxation and the start of left ventricular filling." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Mondofacto:Mondofacto_Online_Medical_Dictionary, http://123sonography.com/node/943] synonym: "calculated LV-IVRT" RELATED [] is_a: CMO:0002540 ! left ventricular isovolumetric relaxation time created_by: JSMITH @@ -23142,7 +23142,7 @@ creation_date: 2014-08-18T12:04:19Z [Term] id: CMO:0002554 name: mitral valve closure to opening time -def: "Measurement of the length of time between the closing of the mitral valve (the dual-flap valve in the heart that controls blood flow between the left atrium and the left ventricle) at the end of ventricular filling (that is, after atrial contraction) and its opening at the beginning of the next round of ventricular filling." [Wikipedia:http\://en.wikipedia.org/wiki/Mitral_Valve] +def: "Measurement of the length of time between the closing of the mitral valve (the dual-flap valve in the heart that controls blood flow between the left atrium and the left ventricle) at the end of ventricular filling (that is, after atrial contraction) and its opening at the beginning of the next round of ventricular filling." [https://en.wikipedia.org/wiki/Mitral_Valve] synonym: "MV co" RELATED [] is_a: CMO:0000662 ! heart contraction measurement created_by: JSMITH @@ -23151,7 +23151,7 @@ creation_date: 2014-08-18T12:19:05Z [Term] id: CMO:0002555 name: left ventricular ejection time -def: "The time interval from the opening to the closing of the aortic valve (mechanical systole)." [Wikipedia:http\://en.wikipedia.org/wiki/Impedance_cardiography] +def: "The time interval from the opening to the closing of the aortic valve (mechanical systole)." [https://en.wikipedia.org/wiki/Impedance_cardiography] synonym: "LVET" RELATED [] is_a: CMO:0000981 ! ventricle contraction measurement created_by: JSMITH @@ -23323,7 +23323,7 @@ creation_date: 2014-08-26T11:52:08Z [Term] id: CMO:0002573 name: absolute change in urine epinephrine excretion rate -def: "The calculated difference in urine epinephrine excretion rate between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The calculated difference in urine epinephrine excretion rate between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in urine adrenaline excretion rate" EXACT [] xref: CHEBI:33568 @@ -23335,7 +23335,7 @@ creation_date: 2014-08-26T12:21:52Z [Term] id: CMO:0002574 name: absolute change in urine norepinephrine excretion rate -def: "The calculated difference in urine norepinephrine excretion rate between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The calculated difference in urine norepinephrine excretion rate between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in urine noradrenaline excretion rate" EXACT [] xref: CHEBI:33569 @@ -23347,7 +23347,7 @@ creation_date: 2014-08-26T12:23:42Z [Term] id: CMO:0002575 name: absolute change in urine vanillylmandelic acid excretion rate -def: "The calculated difference in urine vanillylmandelic acid excretion rate between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, Website:http\://www.psychwiki.com/wiki/What_is_absolute_change%3F] +def: "The calculated difference in urine vanillylmandelic acid excretion rate between two points in time or two conditions expressed as the result of the subtraction in and of itself without comparison by ratio with another quantity." [Collins:Collins_Online_English_Dictionary, http://www.psychwiki.com/wiki/What_is_absolute_change%3F] comment: The term "absolute change" refers to the subtraction of one value from another, as opposed to a dissimilarity of two values expressed as a ratio or as a percentage. In this context it is not intended to necessarily imply the difference expressed as an absolute value |n|, that is, the numeric value of the difference without regard to its sign. synonym: "absolute change in urine 3-methoxy-4-hydroxymandelic acid excretion rate" EXACT [] synonym: "absolute change in urine VMA excretion rate" RELATED [] @@ -23477,7 +23477,7 @@ creation_date: 2014-08-26T18:07:46Z [Term] id: CMO:0002589 name: blood pressure time series calculated parameter -def: "A calculated parameter derived from a a sequence of blood pressure measurements taken sequentially and ordered in time. A parameter is a mathematical and statistical variable in a model system that partially or completely characterises the mathematical model." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Segen:Segens_Medical_Dictionary_2012, Website:http\://www.stats.gla.ac.uk/steps/glossary/time_series.html#timeseries] +def: "A calculated parameter derived from a a sequence of blood pressure measurements taken sequentially and ordered in time. A parameter is a mathematical and statistical variable in a model system that partially or completely characterises the mathematical model." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, Segen:Segens_Medical_Dictionary_2012, http://www.stats.gla.ac.uk/steps/glossary/time_series.html#timeseries] is_a: CMO:0000008 ! calculated blood pressure created_by: JSmith creation_date: 2014-09-11T17:13:44Z @@ -23493,7 +23493,7 @@ creation_date: 2014-09-11T18:09:25Z [Term] id: CMO:0002591 name: blood pressure time series first order moving average coefficient -def: "The first order coefficient parameter derived from a blood pressure time series moving average (also known as a rolling average, running average, moving mean, or rolling mean) calculation." [PMID:11973321, PMID:14532335, Wikipedia:http\://en.wikipedia.org/wiki/Moving_average] +def: "The first order coefficient parameter derived from a blood pressure time series moving average (also known as a rolling average, running average, moving mean, or rolling mean) calculation." [PMID:11973321, PMID:14532335, https://en.wikipedia.org/wiki/Moving_average] is_a: CMO:0002589 ! blood pressure time series calculated parameter created_by: JSmith creation_date: 2014-09-11T18:10:33Z @@ -23501,7 +23501,7 @@ creation_date: 2014-09-11T18:10:33Z [Term] id: CMO:0002592 name: blood pressure time series fractal parameter -def: "The fractal parameter derived from a blood pressure time series calculation based on a autoregressive fractionally integrated moving average time series model (ARFIMA, FARIMA, or fARIMA)." [PMID:11973321, PMID:14532335, Wikipedia:http\://en.wikipedia.org/wiki/Autoregressive_fractionally_integrated_moving_average] +def: "The fractal parameter derived from a blood pressure time series calculation based on a autoregressive fractionally integrated moving average time series model (ARFIMA, FARIMA, or fARIMA)." [PMID:11973321, PMID:14532335, https://en.wikipedia.org/wiki/Autoregressive_fractionally_integrated_moving_average] is_a: CMO:0002589 ! blood pressure time series calculated parameter created_by: JSmith creation_date: 2014-09-11T18:24:22Z @@ -23541,7 +23541,7 @@ creation_date: 2014-09-11T18:33:53Z [Term] id: CMO:0002597 name: heart left ventricle end-diastolic posterior wall thickness -def: "The thickness or depth (i.e. the measurement of the two-dimensional extent of the distance between the inner and outer surfaces) of the dorsal/posterior wall of the left ventricle of the heart at the end of diastole, that is, when the heart muscle is maximally relaxed. The dorsal wall is the portion of the muscle enclosing the ventricle which is closest to the spine and farthest from the chest wall of the organism." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location)] +def: "The thickness or depth (i.e. the measurement of the two-dimensional extent of the distance between the inner and outer surfaces) of the dorsal/posterior wall of the left ventricle of the heart at the end of diastole, that is, when the heart muscle is maximally relaxed. The dorsal wall is the portion of the muscle enclosing the ventricle which is closest to the spine and farthest from the chest wall of the organism." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Anatomical_terms_of_location)] comment: Note that "left" in this context refers to the perspective of the organism, not that of the observer. synonym: "end-diastolic heart left ventricle posterior wall thickness" EXACT [] synonym: "end-diastolic heart left ventricle PWT" RELATED [] @@ -23563,7 +23563,7 @@ creation_date: 2014-10-31T17:13:09Z [Term] id: CMO:0002599 name: serum paracetamol level area under curve (AUC) -def: "A calculated measurement in which a series of measurements of the amount of paracetamol (also known as acetaminophen) in a specified volume of serum is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Wikipedia:http\://en.wikipedia.org/wiki/Area_under_curve] +def: "A calculated measurement in which a series of measurements of the amount of paracetamol (also known as acetaminophen) in a specified volume of serum is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [https://en.wikipedia.org/wiki/Area_under_curve] synonym: "serum acetaminophen AUC" RELATED [] synonym: "serum acetaminophen level area under curve" EXACT [] xref: CHEBI:46195 @@ -23575,7 +23575,7 @@ creation_date: 2014-10-31T17:17:00Z [Term] id: CMO:0002600 name: hepatocellular carcinoma tumor number -def: "A value or quantity determined by count of hepatocellular carcinoma tumors in the liver or in a specified sample of liver tissue, i.e. growths that result from uncontrolled, progressive multiplication of cells, that serve no physiological function, and that display the properties of anaplasia, invasiveness and metastasis. Hepatocellular carcinomas (HCC) are primary malignant neoplasms of hepatocytes, epithelial liver cells which perform the functions of the liver such as transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, detoxification of exogenous substances, etc. HCC is often associated with cirrhosis and hepatitis B and/or C infection." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Hepatocellular_carcinoma, Wikipedia:http\://en.wikipedia.org/wiki/Hepatocyte] +def: "A value or quantity determined by count of hepatocellular carcinoma tumors in the liver or in a specified sample of liver tissue, i.e. growths that result from uncontrolled, progressive multiplication of cells, that serve no physiological function, and that display the properties of anaplasia, invasiveness and metastasis. Hepatocellular carcinomas (HCC) are primary malignant neoplasms of hepatocytes, epithelial liver cells which perform the functions of the liver such as transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, detoxification of exogenous substances, etc. HCC is often associated with cirrhosis and hepatitis B and/or C infection." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Hepatocellular_carcinoma, https://en.wikipedia.org/wiki/Hepatocyte] synonym: "HCC tumor number" RELATED [] synonym: "hepatocellular carcinoma tumor count" EXACT [] synonym: "malignant hepatocellular carcinoma tumor number" EXACT [] @@ -23611,7 +23611,7 @@ creation_date: 2014-11-03T13:20:43Z [Term] id: CMO:0002603 name: hepatocellular carcinoma incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display hepatocellular carcinoma at a point in time or develop hepatocellular carcinoma within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. Hepatocellular carcinomas (HCC) are primary malignant neoplasms of hepatocytes, epithelial liver cells which perform the functions of the liver such as transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, detoxification of exogenous substances, etc. HCC is often associated with cirrhosis and hepatitis B and/or C infection." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Hepatocellular_carcinoma, Wikipedia:http\://en.wikipedia.org/wiki/Hepatocyte] +def: "Any measurement in which the number of individuals in a study population that display hepatocellular carcinoma at a point in time or develop hepatocellular carcinoma within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. Hepatocellular carcinomas (HCC) are primary malignant neoplasms of hepatocytes, epithelial liver cells which perform the functions of the liver such as transformation of carbohydrates, synthesis of cholesterol, bile salts and phospholipids, detoxification of exogenous substances, etc. HCC is often associated with cirrhosis and hepatitis B and/or C infection." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Hepatocellular_carcinoma, https://en.wikipedia.org/wiki/Hepatocyte] synonym: "malignant hepatocellular carcinoma incidence/prevalence measurement" EXACT [] xref: MESH:D006528 is_a: CMO:0001710 ! malignant liver tumor incidence/prevalence measurement @@ -23621,7 +23621,7 @@ creation_date: 2014-11-03T13:20:43Z [Term] id: CMO:0002604 name: plasma E. coli specific antibody titer -def: "The amount of immunoglobulin molecule with an amino acid sequence that binds with Escherichia coli, a Gram negative rod-shaped bacterium, in a specific volume of plasma expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "The amount of immunoglobulin molecule with an amino acid sequence that binds with Escherichia coli, a Gram negative rod-shaped bacterium, in a specific volume of plasma expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "plasma Escherichia coli specific antibody titer" EXACT [] is_a: CMO:0000479 ! plasma E. coli specific antibody level is_a: CMO:0002618 ! plasma antibody titer @@ -23665,7 +23665,7 @@ creation_date: 2014-11-07T17:54:24Z [Term] id: CMO:0002609 name: serum immunoglobulin M-type rheumatoid factor level -def: "The amount in a specified sample of serum of rheumatoid factor that is expressed as an immunoglobulin M (IgM) molecule. Rheumatoid factor (RF) is an autoantibody against the Fc portion of IgG found in rheumatoid arthritis and some other autoimmune diseases. RF and IgG join to form immune complexes that contribute to the disease process." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Rheumatoid_factor] +def: "The amount in a specified sample of serum of rheumatoid factor that is expressed as an immunoglobulin M (IgM) molecule. Rheumatoid factor (RF) is an autoantibody against the Fc portion of IgG found in rheumatoid arthritis and some other autoimmune diseases. RF and IgG join to form immune complexes that contribute to the disease process." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Rheumatoid_factor] synonym: "serum IgM-RF level" RELATED [] synonym: "serum IgM-rheumatoid factor level" RELATED [] is_a: CMO:0002104 ! serum immunoglobulin M level @@ -23676,7 +23676,7 @@ creation_date: 2014-11-10T12:17:32Z [Term] id: CMO:0002610 name: serum immunoglobulin G-type rheumatoid factor level -def: "The amount in a specified sample of serum of rheumatoid factor that is expressed as an immunoglobulin G (IgG) molecule. Rheumatoid factor (RF) is an autoantibody against the Fc portion of IgG found in rheumatoid arthritis and some other autoimmune diseases. RF and IgG join to form immune complexes that contribute to the disease process." [Wikipedia:http\://en.wikipedia.org/wiki/Rheumatoid_factor] +def: "The amount in a specified sample of serum of rheumatoid factor that is expressed as an immunoglobulin G (IgG) molecule. Rheumatoid factor (RF) is an autoantibody against the Fc portion of IgG found in rheumatoid arthritis and some other autoimmune diseases. RF and IgG join to form immune complexes that contribute to the disease process." [https://en.wikipedia.org/wiki/Rheumatoid_factor] synonym: "serum IgG-RF level" RELATED [] synonym: "serum IgG-rheumatoid factor level" RELATED [] is_a: CMO:0002102 ! serum immunoglobulin G level @@ -23687,7 +23687,7 @@ creation_date: 2014-11-10T12:23:08Z [Term] id: CMO:0002611 name: serum immunoglobulin G-type rheumatoid factor titer -def: "The level of rheumatoid factor that is expressed as an immunoglobulin G (IgG) molecule in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [Wikipedia:http\://en.wikipedia.org/wiki/Rheumatoid_factor, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "The level of rheumatoid factor that is expressed as an immunoglobulin G (IgG) molecule in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [https://en.wikipedia.org/wiki/Rheumatoid_factor, https://en.wikipedia.org/wiki/Titer] synonym: "serum IgG-RFtiter" RELATED [] synonym: "serum IgG-rheumatoid factor titer" RELATED [] is_a: CMO:0002610 ! serum immunoglobulin G-type rheumatoid factor level @@ -23698,7 +23698,7 @@ creation_date: 2014-11-10T12:33:41Z [Term] id: CMO:0002612 name: serum immunoglobulin M-type rheumatoid factor titer -def: "The amount of rheumatoid factor that is expressed as an immunoglobulin M (IgM) molecule in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Wikipedia:http\://en.wikipedia.org/wiki/Rheumatoid_factor, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "The amount of rheumatoid factor that is expressed as an immunoglobulin M (IgM) molecule in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://en.wikipedia.org/wiki/Rheumatoid_factor, https://en.wikipedia.org/wiki/Titer] synonym: "serum IgM-RF titer" RELATED [] synonym: "serum IgM-rheumatoid factor titer" RELATED [] is_a: CMO:0002609 ! serum immunoglobulin M-type rheumatoid factor level @@ -23709,7 +23709,7 @@ creation_date: 2014-11-10T12:37:07Z [Term] id: CMO:0002613 name: blood autoantibody titer -def: "Measurement of the amount of a specific autoantibody in a specified sample of blood, determined as the maximal dilution of the sample at which that antibody can still be detected. The value represents the denominator of the dilution ratio, i.e., a titer of 32 means that the sample can be maximally diluted 1/32 and still contain enough antibody to be detected." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Antibody_titer] +def: "Measurement of the amount of a specific autoantibody in a specified sample of blood, determined as the maximal dilution of the sample at which that antibody can still be detected. The value represents the denominator of the dilution ratio, i.e., a titer of 32 means that the sample can be maximally diluted 1/32 and still contain enough antibody to be detected." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Antibody_titer] synonym: "blood anti-self antibody titer" EXACT [] is_a: CMO:0001863 ! autoantibody titer is_a: CMO:0002107 ! blood autoantibody level @@ -23728,7 +23728,7 @@ creation_date: 2014-11-10T12:54:02Z [Term] id: CMO:0002615 name: plasma autoantibody titer -def: "Measurement of the amount of one or more autoantibodies in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "Measurement of the amount of one or more autoantibodies in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-self antibody titer" EXACT [] is_a: CMO:0002108 ! plasma autoantibody level is_a: CMO:0002613 ! blood autoantibody titer @@ -23739,7 +23739,7 @@ creation_date: 2014-11-10T13:00:56Z [Term] id: CMO:0002616 name: serum autoantibody titer -def: "Measurement of the amount of one or more autoantibodies in a specified sample of serum, expressed as the last dilution of serum at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "Measurement of the amount of one or more autoantibodies in a specified sample of serum, expressed as the last dilution of serum at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "serum anti-self antibody titer" EXACT [] is_a: CMO:0002109 ! serum autoantibody level is_a: CMO:0002613 ! blood autoantibody titer @@ -23750,7 +23750,7 @@ creation_date: 2014-11-10T13:03:46Z [Term] id: CMO:0002617 name: blood antibody titer -def: "A measurement of the amount of a specific antibody in a specified sample of blood, expressed as the last dilution of plasma at which a positive result could be obtained." [Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of a specific antibody in a specified sample of blood, expressed as the last dilution of plasma at which a positive result could be obtained." [https://en.wikipedia.org/wiki/Titer] is_a: CMO:0001828 ! blood antibody level is_a: CMO:0001862 ! antibody titer created_by: JSmith @@ -23759,7 +23759,7 @@ creation_date: 2014-11-10T13:15:00Z [Term] id: CMO:0002618 name: plasma antibody titer -def: "A measurement of the amount of a specific antibody in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of a specific antibody in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Titer] is_a: CMO:0000478 ! plasma antibody level is_a: CMO:0002617 ! blood antibody titer created_by: JSmith @@ -23768,7 +23768,7 @@ creation_date: 2014-11-10T13:15:38Z [Term] id: CMO:0002619 name: serum antibody titer -def: "A measurement of the amount of a specific antibody in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained. Serum is the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of a specific antibody in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained. Serum is the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] is_a: CMO:0001277 ! serum antibody level is_a: CMO:0002617 ! blood antibody titer created_by: JSmith @@ -23777,7 +23777,7 @@ creation_date: 2014-11-10T13:15:43Z [Term] id: CMO:0002620 name: serum anti-rat type 2 collagen antibody level -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds rat-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds rat-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "serum anti-rat type II collagen antibody level" EXACT [] is_a: CMO:0002627 ! serum anti-type 2 collagen antibody level created_by: JSmith @@ -23786,7 +23786,7 @@ creation_date: 2014-11-11T12:44:25Z [Term] id: CMO:0002621 name: serum anti-rat type 2 collagen autoantibody level -def: "The amount in a specified sample of serum, of an immunoglobulin molecule, specifically one produced by the immune system of a rat against its own collagen, possessing a specific amino acid sequence that binds rat-derived type 2 collagen." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount in a specified sample of serum, of an immunoglobulin molecule, specifically one produced by the immune system of a rat against its own collagen, possessing a specific amino acid sequence that binds rat-derived type 2 collagen." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "serum anti-rat type II collagen autoantibody level" EXACT [] synonym: "serum rat anti-self type 2 collagen antibody level" EXACT [] is_a: CMO:0002109 ! serum autoantibody level @@ -23797,7 +23797,7 @@ creation_date: 2014-11-11T12:51:51Z [Term] id: CMO:0002622 name: serum anti-porcine type 2 collagen antibody level -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "serum anti-porcine type II collagen antibody level" EXACT [] is_a: CMO:0002627 ! serum anti-type 2 collagen antibody level created_by: JSmith @@ -23806,7 +23806,7 @@ creation_date: 2014-11-11T13:50:36Z [Term] id: CMO:0002623 name: serum anti-porcine type 2 collagen antibody titer -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen in a specified sample of serum expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen in a specified sample of serum expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "serum anti-porcine type II collagen antibody titer" EXACT [] is_a: CMO:0002622 ! serum anti-porcine type 2 collagen antibody level is_a: CMO:0002625 ! serum anti-type 2 collagen antibody titer @@ -23816,7 +23816,7 @@ creation_date: 2014-11-11T15:05:05Z [Term] id: CMO:0002624 name: serum anti-rat type 2 collagen autoantibody titer -def: "The amount in a specified sample of serum, of an immunoglobulin molecule, specifically one produced by the immune system of a rat against its own collagen, possessing a specific amino acid sequence that binds rat-derived type 2 collagen, expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount in a specified sample of serum, of an immunoglobulin molecule, specifically one produced by the immune system of a rat against its own collagen, possessing a specific amino acid sequence that binds rat-derived type 2 collagen, expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "serum anti-rat type II collagen autoantibody titer" EXACT [] synonym: "serum rat anti-self type 2 collagen antibody titer" EXACT [] is_a: CMO:0002616 ! serum autoantibody titer @@ -23828,7 +23828,7 @@ creation_date: 2014-11-11T15:08:26Z [Term] id: CMO:0002625 name: serum anti-type 2 collagen antibody titer -def: "Measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen in a specified volume of serum expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "Measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen in a specified volume of serum expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "serum anti-type II collagen antibody titer" EXACT [] is_a: CMO:0002627 ! serum anti-type 2 collagen antibody level is_a: CMO:0002629 ! serum anti-collagen antibody titer @@ -23838,7 +23838,7 @@ creation_date: 2014-11-11T15:20:24Z [Term] id: CMO:0002626 name: serum anti-rat type 2 collagen antibody titer -def: "The amount in a specified sample of serum, of an immunoglobulin molecule possessing a specific amino acid sequence that binds rat-derived type 2 collagen, expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount in a specified sample of serum, of an immunoglobulin molecule possessing a specific amino acid sequence that binds rat-derived type 2 collagen, expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "serum anti-rat type II collagen antibody titer" EXACT [] is_a: CMO:0002620 ! serum anti-rat type 2 collagen antibody level is_a: CMO:0002625 ! serum anti-type 2 collagen antibody titer @@ -23848,7 +23848,7 @@ creation_date: 2014-11-11T15:24:09Z [Term] id: CMO:0002627 name: serum anti-type 2 collagen antibody level -def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "serum anti-type II collagen antibody level" EXACT [] is_a: CMO:0001280 ! serum anti-collagen antibody level created_by: JSmith @@ -23857,7 +23857,7 @@ creation_date: 2014-11-11T15:39:23Z [Term] id: CMO:0002628 name: serum anti-laminin antibody titer -def: "Measurement of the amount of immunoglobulin molecule with an amino acid sequence that specifically binds to laminin, in a specified sample of serum expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "Measurement of the amount of immunoglobulin molecule with an amino acid sequence that specifically binds to laminin, in a specified sample of serum expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, https://en.wikipedia.org/wiki/Titer] is_a: CMO:0001539 ! serum anti-laminin antibody level is_a: CMO:0002608 ! blood anti-laminin antibody level is_a: CMO:0002619 ! serum antibody titer @@ -23867,7 +23867,7 @@ creation_date: 2014-11-11T16:23:25Z [Term] id: CMO:0002629 name: serum anti-collagen antibody titer -def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds to one or more types of collagen, the fibrous protein constituent of bone, cartilage, tendon, and other connective tissue, in a specified volume of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds to one or more types of collagen, the fibrous protein constituent of bone, cartilage, tendon, and other connective tissue, in a specified volume of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] is_a: CMO:0001280 ! serum anti-collagen antibody level is_a: CMO:0002619 ! serum antibody titer created_by: JSmith @@ -23876,7 +23876,7 @@ creation_date: 2014-11-11T16:32:12Z [Term] id: CMO:0002630 name: serum anti-DNA antibody titer -def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to deoxyribonucleic acid (DNA) in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to deoxyribonucleic acid (DNA) in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "serum anti-deoxyribonucleic acid antibody titer" EXACT [] is_a: CMO:0001533 ! serum anti-DNA antibody level is_a: CMO:0002619 ! serum antibody titer @@ -23886,7 +23886,7 @@ creation_date: 2014-11-11T16:41:37Z [Term] id: CMO:0002631 name: serum anti-dsDNA antibody titer -def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to double-stranded deoxyribonucleic acid (DNA), a molecule composed of two anti-parallel, hydrogen-bonded, polymeric strands of nucleic acids in which the sugar is deoxyribose and which is also composed of phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to double-stranded deoxyribonucleic acid (DNA), a molecule composed of two anti-parallel, hydrogen-bonded, polymeric strands of nucleic acids in which the sugar is deoxyribose and which is also composed of phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "serum anti-double-stranded deoxyribonucleic acid antibody titer" EXACT [] synonym: "serum anti-double-stranded DNA antibody titer" EXACT [] is_a: CMO:0001534 ! serum anti-dsDNA antibody level @@ -23897,7 +23897,7 @@ creation_date: 2014-11-11T16:43:10Z [Term] id: CMO:0002632 name: serum anti-ssDNA antibody titer -def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to single-stranded deoxyribonucleic acid (DNA), a single polymeric strand of nucleic acids in which the sugar is deoxyribose and which is also composed of phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to single-stranded deoxyribonucleic acid (DNA), a single polymeric strand of nucleic acids in which the sugar is deoxyribose and which is also composed of phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, in a specified sample of serum, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "serum anti-single-stranded deoxyribonucleic acid antibody titer" EXACT [] synonym: "serum anti-single-stranded DNA antibody titer" EXACT [] is_a: CMO:0001535 ! serum anti-ssDNA antibody level @@ -23908,7 +23908,7 @@ creation_date: 2014-11-11T16:47:10Z [Term] id: CMO:0002633 name: plasma anti-laminin antibody titer -def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that specifically binds to laminin, a large polypeptide glycoprotein component of basement membranes, in a specific sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that specifically binds to laminin, a large polypeptide glycoprotein component of basement membranes, in a specific sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Dental_Dictionary--2nd_Ed, https://en.wikipedia.org/wiki/Titer] is_a: CMO:0001540 ! plasma anti-laminin antibody level is_a: CMO:0002608 ! blood anti-laminin antibody level is_a: CMO:0002618 ! plasma antibody titer @@ -23918,7 +23918,7 @@ creation_date: 2014-11-11T17:03:34Z [Term] id: CMO:0002634 name: plasma anti-DNA antibody titer -def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to deoxyribonucleic acid (DNA) in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to deoxyribonucleic acid (DNA) in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-deoxyribonucleic acid antibody titer" EXACT [] is_a: CMO:0001538 ! plasma anti-DNA antibody level is_a: CMO:0002618 ! plasma antibody titer @@ -23928,7 +23928,7 @@ creation_date: 2014-11-11T17:06:37Z [Term] id: CMO:0002635 name: plasma anti-dsDNA antibody titer -def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to double-stranded deoxyribonucleic acid (DNA), a molecule composed of two anti-parallel, hydrogen-bonded, polymeric strands of nucleic acids in which the sugar is deoxyribose and which is also composed of phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to double-stranded deoxyribonucleic acid (DNA), a molecule composed of two anti-parallel, hydrogen-bonded, polymeric strands of nucleic acids in which the sugar is deoxyribose and which is also composed of phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-double-stranded deoxyribonucleic acid antibody titer" EXACT [] synonym: "plasma anti-double-stranded DNA antibody titer" EXACT [] is_a: CMO:0001537 ! plasma anti-dsDNA antibody level @@ -23939,7 +23939,7 @@ creation_date: 2014-11-11T17:08:55Z [Term] id: CMO:0002636 name: plasma anti-ssDNA antibody titer -def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to single-stranded deoxyribonucleic acid (DNA), a single polymeric strand of nucleic acids in which the sugar is deoxyribose and which is also composed of phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of immunoglobulin molecule with an amino acid sequence that binds to single-stranded deoxyribonucleic acid (DNA), a single polymeric strand of nucleic acids in which the sugar is deoxyribose and which is also composed of phosphate groups and any combination of the bases adenine, guanine, cytosine, and/or thymine, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-single-stranded deoxyribonucleic acid antibody titer" EXACT [] synonym: "plasma anti-single-stranded DNA antibody titer" EXACT [] is_a: CMO:0001536 ! plasma anti-ssDNA antibody level @@ -23950,7 +23950,7 @@ creation_date: 2014-11-11T17:13:26Z [Term] id: CMO:0002637 name: plasma anti-collagen antibody titer -def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds to one or more types of collagen, the fibrous protein constituent of bone, cartilage, tendon, and other connective tissue, in a specified volume of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds to one or more types of collagen, the fibrous protein constituent of bone, cartilage, tendon, and other connective tissue, in a specified volume of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Titer] is_a: CMO:0001271 ! plasma anti-collagen antibody level is_a: CMO:0002618 ! plasma antibody titer created_by: JSmith @@ -23959,7 +23959,7 @@ creation_date: 2014-11-11T17:18:49Z [Term] id: CMO:0002638 name: plasma anti-type 2 collagen antibody titer -def: "Measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum,expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "Measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of serum,expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-type II collagen antibody titer" EXACT [] is_a: CMO:0001272 ! plasma anti-type 2 collagen antibody level is_a: CMO:0002637 ! plasma anti-collagen antibody titer @@ -23969,7 +23969,7 @@ creation_date: 2014-11-11T17:21:00Z [Term] id: CMO:0002639 name: plasma anti-bovine type 2 collagen antibody titer -def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds cattle-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds cattle-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-bovine type II collagen antibody titer" EXACT [] is_a: CMO:0001273 ! plasma anti-bovine type 2 collagen antibody level is_a: CMO:0002638 ! plasma anti-type 2 collagen antibody titer @@ -23979,7 +23979,7 @@ creation_date: 2014-11-11T17:25:01Z [Term] id: CMO:0002640 name: plasma anti-porcine type 2 collagen antibody titer -def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds pig-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-porcine type II collagen antibody titer" EXACT [] is_a: CMO:0001274 ! plasma anti-porcine type 2 collagen antibody level is_a: CMO:0002638 ! plasma anti-type 2 collagen antibody titer @@ -23989,7 +23989,7 @@ creation_date: 2014-11-11T17:28:16Z [Term] id: CMO:0002641 name: plasma anti-rat type 2 collagen autoantibody level -def: "The amount of an immunoglobulin molecule produced by the immune system of a rat and possessing a specific amino acid sequence that binds its own type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen] +def: "The amount of an immunoglobulin molecule produced by the immune system of a rat and possessing a specific amino acid sequence that binds its own type 2 collagen, the main fibrous protein constituent of cartilage, in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen] synonym: "plasma anti-rat type II collagen autoantibody level" EXACT [] synonym: "plasma rat anti-self type 2 collagen antibody level" EXACT [] is_a: CMO:0001275 ! plasma anti-rat type 2 collagen antibody level @@ -24000,7 +24000,7 @@ creation_date: 2014-11-11T17:31:09Z [Term] id: CMO:0002642 name: plasma anti-rat type 2 collagen antibody titer -def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds rat-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds rat-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-rat type II collagen antibody titer" EXACT [] is_a: CMO:0001275 ! plasma anti-rat type 2 collagen antibody level is_a: CMO:0002638 ! plasma anti-type 2 collagen antibody titer @@ -24010,7 +24010,7 @@ creation_date: 2014-11-11T17:31:13Z [Term] id: CMO:0002643 name: plasma anti-rat type 2 collagen autoantibody titer -def: "A measurement of the amount of an immunoglobulin molecule produced by the immune system of a rat and possessing a specific amino acid sequence that binds its own type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of an immunoglobulin molecule produced by the immune system of a rat and possessing a specific amino acid sequence that binds its own type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of plasma, expressed as the last dilution of plasma at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "plasma anti-rat type II collagen autoantibody titer" EXACT [] synonym: "plasma rat anti-self type 2 collagen antibody titer" EXACT [] is_a: CMO:0002615 ! plasma autoantibody titer @@ -24022,7 +24022,7 @@ creation_date: 2014-11-11T17:43:45Z [Term] id: CMO:0002644 name: serum anti-bovine type 2 collagen antibody titer -def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds cattle-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of serum, expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:http\://en.wikipedia.org/wiki/Collagen, Wikipedia:http\://en.wikipedia.org/wiki/Titer] +def: "A measurement of the amount of an immunoglobulin molecule possessing a specific amino acid sequence that binds cattle-derived type 2 collagen, the main fibrous protein constituent of cartilage, in a specified sample of serum, expressed as the last dilution of serum at which a positive result could be obtained." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Collagen, https://en.wikipedia.org/wiki/Titer] synonym: "serum anti-bovine type II collagen antibody titer" EXACT [] is_a: CMO:0001282 ! serum anti-bovine type 2 collagen antibody level is_a: CMO:0002625 ! serum anti-type 2 collagen antibody titer @@ -24032,7 +24032,7 @@ creation_date: 2014-11-12T09:21:17Z [Term] id: CMO:0002645 name: bone ash content -def: "The amount of ash produced by the calcination of bone, that is, a thermal treatment of bone resulting in thermal decomposition and/or removal of the volatile fraction." [Wikipedia:http\://en.wikipedia.org/wiki/Bone_ash] +def: "The amount of ash produced by the calcination of bone, that is, a thermal treatment of bone resulting in thermal decomposition and/or removal of the volatile fraction." [https://en.wikipedia.org/wiki/Bone_ash] synonym: "Ca5(OH)(PO4)3 content" RELATED [] is_a: CMO:0001554 ! bone mineral content created_by: JSmith @@ -24068,7 +24068,7 @@ creation_date: 2015-03-06T18:45:10Z [Term] id: CMO:0002649 name: femur metaphysial mediolateral diameter -def: "The distance between two specified opposite points on the periphery of the femur metaphysis measured from one side to the other, that is, along the mediolateral axis of the bone." [Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location#Medial_and_lateral] +def: "The distance between two specified opposite points on the periphery of the femur metaphysis measured from one side to the other, that is, along the mediolateral axis of the bone." [Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Anatomical_terms_of_location#Medial_and_lateral] synonym: "femoral metaphysis mediolateral diameter" EXACT [] synonym: "femur metaphysial medio-lateral diameter" EXACT [] is_a: CMO:0002648 ! femur metaphysis morphological measurement @@ -24078,7 +24078,7 @@ creation_date: 2015-03-06T18:46:31Z [Term] id: CMO:0002650 name: femur metaphysial anterior-posterior diameter -def: "The distance between two specified opposite points on the periphery of the femur metaphysis measured from front to back, that is, along the anteroposterior axis of the bone." [Mosby:Mosbys_Medical_Dictionary--8th_Ed, Wikipedia:http\://en.wikipedia.org/wiki/Anatomical_terms_of_location#Anterior_and_posterior] +def: "The distance between two specified opposite points on the periphery of the femur metaphysis measured from front to back, that is, along the anteroposterior axis of the bone." [Mosby:Mosbys_Medical_Dictionary--8th_Ed, https://en.wikipedia.org/wiki/Anatomical_terms_of_location#Anterior_and_posterior] synonym: "femoral metaphysis anteroposterior diameter" EXACT [] synonym: "femur metaphysial anteroposterior diameter" EXACT [] is_a: CMO:0002648 ! femur metaphysis morphological measurement @@ -24164,7 +24164,7 @@ creation_date: 2015-04-29T08:46:53Z [Term] id: CMO:0002659 name: logarithm of the total number of Haemophilus influenzae bacterial colony forming units recovered -def: "The logarithm of the enumeration, i.e. measurement of the total number, of colony forming units (CFUs) of the bacterial species Haemophilus influenzae in a specified sample of fluid removed from and/or solution used to wash the interior of a cavity in a body or an organ. Haemophilus influenzae is a Gram-negative, coccobacillary, facultatively anaerobic bacterium which is considered an opportunistic pathogen, i.e. one that can colonize a host without causing disease unless there are extenuating circumstances which result in susceptibility on the part of the host." [PMID:21646454, RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Haemophilus_influenzae] +def: "The logarithm of the enumeration, i.e. measurement of the total number, of colony forming units (CFUs) of the bacterial species Haemophilus influenzae in a specified sample of fluid removed from and/or solution used to wash the interior of a cavity in a body or an organ. Haemophilus influenzae is a Gram-negative, coccobacillary, facultatively anaerobic bacterium which is considered an opportunistic pathogen, i.e. one that can colonize a host without causing disease unless there are extenuating circumstances which result in susceptibility on the part of the host." [PMID:21646454, RGD:JRS, https://en.wikipedia.org/wiki/Haemophilus_influenzae] synonym: "logarithm of the total number of H. influenzae CFU in effusion plus wash" RELATED [] synonym: "Log recovered H. influenzae CFU" RELATED [] xref: NCBI_Taxon:727 @@ -24175,7 +24175,7 @@ creation_date: 2015-04-29T08:53:56Z [Term] id: CMO:0002660 name: logarithm of the total number of Streptococcus pneumoniae bacterial colony forming units recovered -def: "The logarithm of the enumeration, i.e. measurement of the total number, of colony forming units (CFUs) of the bacterial species Streptococcus pneumoniae in a specified sample of fluid removed from and/or solution used to wash the interior of a cavity in a body or an organ. Streptococcus pneumoniae is a species of Gram-positive, alpha-hemolytic, facultative anaerobic bacteria commonly found in the nasopharynx of healthy human carriers." [PMID:21646454, RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Streptococcus_pneumoniae] +def: "The logarithm of the enumeration, i.e. measurement of the total number, of colony forming units (CFUs) of the bacterial species Streptococcus pneumoniae in a specified sample of fluid removed from and/or solution used to wash the interior of a cavity in a body or an organ. Streptococcus pneumoniae is a species of Gram-positive, alpha-hemolytic, facultative anaerobic bacteria commonly found in the nasopharynx of healthy human carriers." [PMID:21646454, RGD:JRS, https://en.wikipedia.org/wiki/Streptococcus_pneumoniae] synonym: "logarithm of the total number of S. pneumoniae CFU in effusion plus wash" RELATED [] synonym: "log of the total number of recovered TIGR4 bacterial CFUs" NARROW [] synonym: "Log recovered S. pneumoniae CFU" RELATED [] @@ -24187,7 +24187,7 @@ creation_date: 2015-04-29T08:59:22Z [Term] id: CMO:0002661 name: logarithm of the total number of nontypeable Haemophilus influenzae bacterial colony forming units recovered -def: "The logarithm of the enumeration, i.e. measurement of the total number, of colony forming units (CFUs) of a nontypeable strain of the bacterial species Haemophilus influenzae in a specified sample of fluid removed from and/or solution used to wash the interior of a cavity in a body or an organ. Nontypeable Haemophilus influenzae refers to any unencapsulated strain of the Gram-negative, coccobacillary, facultatively anaerobic bacterium species Haemophilus influenza. Such bacteria lack the capsular antigens used to serotype strains and therefore cannot be classified by serology." [PMID:21646454, RGD:JRS, Wikipedia:http\://en.wikipedia.org/wiki/Haemophilus_influenzae] +def: "The logarithm of the enumeration, i.e. measurement of the total number, of colony forming units (CFUs) of a nontypeable strain of the bacterial species Haemophilus influenzae in a specified sample of fluid removed from and/or solution used to wash the interior of a cavity in a body or an organ. Nontypeable Haemophilus influenzae refers to any unencapsulated strain of the Gram-negative, coccobacillary, facultatively anaerobic bacterium species Haemophilus influenza. Such bacteria lack the capsular antigens used to serotype strains and therefore cannot be classified by serology." [PMID:21646454, RGD:JRS, https://en.wikipedia.org/wiki/Haemophilus_influenzae] synonym: "logarithm of the total number of nontypeable H. influenzae CFU in effusion plus wash" RELATED [] synonym: "log of the total number of recovered NTHi bacterial CFUs" RELATED [] synonym: "Log recovered nontypeable H. influenzae CFU" RELATED [] @@ -24357,7 +24357,7 @@ creation_date: 2015-12-03T13:41:08Z [Term] id: CMO:0002679 name: blood glycerol level -def: "The amount of free glycerol, a trihydroxy sugar alcohol produced by lipolysis of triglycerides in adipose tissue and a precursor for the synthesis of triacylglycerols and phospholipids in the body, found in a specific volume of blood." [Churchill_Livingstone:Dictionary_of_Sport_and_Exercise_Science_and_Medicine_2008, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:https\://en.wikipedia.org/wiki/Glycerol#Metabolism] +def: "The amount of free glycerol, a trihydroxy sugar alcohol produced by lipolysis of triglycerides in adipose tissue and a precursor for the synthesis of triacylglycerols and phospholipids in the body, found in a specific volume of blood." [Churchill_Livingstone:Dictionary_of_Sport_and_Exercise_Science_and_Medicine_2008, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Glycerol#Metabolism] synonym: "blood free glycerol level" RELATED [] is_a: CMO:0000023 ! blood chemistry measurement created_by: jesmith @@ -24366,7 +24366,7 @@ creation_date: 2015-12-03T14:39:13Z [Term] id: CMO:0002680 name: serum blood glycerol level -def: "The amount of free glycerol, a trihydroxy sugar alcohol produced by lipolysis of triglycerides in adipose tissue and a precursor for the synthesis of triacylglycerols and phospholipids in the body, found in a specific volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Churchill_Livingstone:Dictionary_of_Sport_and_Exercise_Science_and_Medicine_2008, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:https\://en.wikipedia.org/wiki/Glycerol#Metabolism] +def: "The amount of free glycerol, a trihydroxy sugar alcohol produced by lipolysis of triglycerides in adipose tissue and a precursor for the synthesis of triacylglycerols and phospholipids in the body, found in a specific volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Churchill_Livingstone:Dictionary_of_Sport_and_Exercise_Science_and_Medicine_2008, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Glycerol#Metabolism] synonym: "serum free glycerol level" RELATED [] is_a: CMO:0002679 ! blood glycerol level created_by: jesmith @@ -24375,7 +24375,7 @@ creation_date: 2015-12-03T14:41:02Z [Term] id: CMO:0002681 name: plasma glycerol level -def: "The amount of free glycerol, a trihydroxy sugar alcohol produced by lipolysis of triglycerides in adipose tissue and a precursor for the synthesis of triacylglycerols and phospholipids in the body, found in a specific volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Churchill_Livingstone:Dictionary_of_Sport_and_Exercise_Science_and_Medicine_2008, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Wikipedia:https\://en.wikipedia.org/wiki/Glycerol#Metabolism] +def: "The amount of free glycerol, a trihydroxy sugar alcohol produced by lipolysis of triglycerides in adipose tissue and a precursor for the synthesis of triacylglycerols and phospholipids in the body, found in a specific volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Churchill_Livingstone:Dictionary_of_Sport_and_Exercise_Science_and_Medicine_2008, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, https://en.wikipedia.org/wiki/Glycerol#Metabolism] synonym: "plasma free glycerol level" RELATED [] is_a: CMO:0002679 ! blood glycerol level created_by: jesmith @@ -24384,7 +24384,7 @@ creation_date: 2015-12-03T14:41:09Z [Term] id: CMO:0002682 name: blood chylomicron cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in chylomicron molecules in a specified volume of blood. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in chylomicron molecules in a specified volume of blood. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0000527 ! blood chylomicron level is_a: CMO:0002696 ! blood lipoprotein cholesterol level created_by: jesmith @@ -24393,7 +24393,7 @@ creation_date: 2015-12-03T14:47:35Z [Term] id: CMO:0002683 name: serum chylomicron cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in chylomicron molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in chylomicron molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0002281 ! serum cholesterol level is_a: CMO:0002682 ! blood chylomicron cholesterol level created_by: jesmith @@ -24402,7 +24402,7 @@ creation_date: 2015-12-03T14:49:07Z [Term] id: CMO:0002684 name: plasma chylomicron cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in chylomicron molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in chylomicron molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0002282 ! plasma cholesterol level is_a: CMO:0002682 ! blood chylomicron cholesterol level created_by: jesmith @@ -24411,7 +24411,7 @@ creation_date: 2015-12-03T14:49:10Z [Term] id: CMO:0002685 name: blood lipoprotein triglyceride level -def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) in a specified volume of blood." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed\,, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in lipoprotein particles (complex molecules that consist of a protein membrane surrounding a core of lipids) in a specified volume of blood." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0000118 ! blood triglyceride level is_a: CMO:0000119 ! blood lipoprotein level created_by: jesmith @@ -24420,7 +24420,7 @@ creation_date: 2015-12-03T14:55:55Z [Term] id: CMO:0002686 name: blood high density lipoprotein triglyceride level -def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in high-density lipoprotein (HDL) molecules in a specified volume of blood. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed\,, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in high-density lipoprotein (HDL) molecules in a specified volume of blood. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] synonym: "blood HDL triglyceride level" RELATED [] is_a: CMO:0002685 ! blood lipoprotein triglyceride level created_by: jesmith @@ -24429,7 +24429,7 @@ creation_date: 2015-12-03T15:09:20Z [Term] id: CMO:0002687 name: blood low density lipoprotein triglyceride level -def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in low-density lipoprotein (LDL) molecules in a specified volume of blood. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed\,, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in low-density lipoprotein (LDL) molecules in a specified volume of blood. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] synonym: "blood LDL triglyceride level" RELATED [] is_a: CMO:0002685 ! blood lipoprotein triglyceride level created_by: jesmith @@ -24438,7 +24438,7 @@ creation_date: 2015-12-03T15:10:57Z [Term] id: CMO:0002688 name: blood very low density lipoprotein triglyceride level -def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in very low-density lipoprotein (VLDL) molecules in a specified volume of blood. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed\,, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in very low-density lipoprotein (VLDL) molecules in a specified volume of blood. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] synonym: "blood VLDL triglyceride level" RELATED [] is_a: CMO:0002685 ! blood lipoprotein triglyceride level created_by: jesmith @@ -24447,7 +24447,7 @@ creation_date: 2015-12-03T15:13:24Z [Term] id: CMO:0002689 name: blood chylomicron triglyceride level -def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in chylomicron molecules in a specified volume of blood. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of triglyceride (any of a group of lipids that are esters formed from one molecule of glycerol and three molecules of one or more fatty acids, are widespread in adipose tissue, and commonly circulate in the blood in the form of lipoproteins) carried in chylomicron molecules in a specified volume of blood. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0000527 ! blood chylomicron level is_a: CMO:0002685 ! blood lipoprotein triglyceride level created_by: jesmith @@ -24473,7 +24473,7 @@ creation_date: 2015-12-03T15:22:01Z [Term] id: CMO:0002692 name: blood high density lipoprotein particle diameter -def: "The diameter, that is the distance between two specified opposite points on the periphery of blood-derived high-density lipoprotein (HDL) particles. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "The diameter, that is the distance between two specified opposite points on the periphery of blood-derived high-density lipoprotein (HDL) particles. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml." [Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] synonym: "blood HDL particle diameter" RELATED [] is_a: CMO:0002691 ! blood lipoprotein particle diameter created_by: jesmith @@ -24482,7 +24482,7 @@ creation_date: 2015-12-03T15:23:19Z [Term] id: CMO:0002693 name: blood low density lipoprotein particle diameter -def: "The diameter, that is the distance between two specified opposite points on the periphery of blood-derived low-density lipoprotein (LDL) particles. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "The diameter, that is the distance between two specified opposite points on the periphery of blood-derived low-density lipoprotein (LDL) particles. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1." [Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] synonym: "blood LDL particle diameter" RELATED [] is_a: CMO:0002691 ! blood lipoprotein particle diameter created_by: jesmith @@ -24491,7 +24491,7 @@ creation_date: 2015-12-03T15:25:01Z [Term] id: CMO:0002694 name: blood very low density lipoprotein particle diameter -def: "The diameter, that is the distance between two specified opposite points on the periphery of blood-derived very low-density lipoprotein (VLDL) particles. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "The diameter, that is the distance between two specified opposite points on the periphery of blood-derived very low-density lipoprotein (VLDL) particles. VLDL constitute a class of large (e.g. approximately 30-80 nm in diameter) lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The VLDL class of lipoproteins has a density between 0.95 and 1.006 g/ml." [Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] synonym: "blood VLDL particle diameter" RELATED [] is_a: CMO:0002691 ! blood lipoprotein particle diameter created_by: jesmith @@ -24500,7 +24500,7 @@ creation_date: 2015-12-03T15:27:06Z [Term] id: CMO:0002695 name: blood chylomicron particle diameter -def: "The diameter, that is the distance between two specified opposite points on the periphery of blood-derived chylomicron particles. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "The diameter, that is the distance between two specified opposite points on the periphery of blood-derived chylomicron particles. Chylomicrons are a class of lipoproteins (approximate density range <0.95 g/ml) that transport exogenous triglycerides and cholesterol from the small intestine to other tissues." [Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0002691 ! blood lipoprotein particle diameter created_by: jesmith creation_date: 2015-12-03T15:28:36Z @@ -24508,7 +24508,7 @@ creation_date: 2015-12-03T15:28:36Z [Term] id: CMO:0002696 name: blood lipoprotein cholesterol level -def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in lipoprotein molecules in a specified volume of blood. Lipoprotein particles are complex molecules that consist of a protein membrane surrounding a core of lipids." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine_2008, ISBN:978-1416049982, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in lipoprotein molecules in a specified volume of blood. Lipoprotein particles are complex molecules that consist of a protein membrane surrounding a core of lipids." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine_2008, ISBN:978-1416049982, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0000119 ! blood lipoprotein level is_a: CMO:0002280 ! blood cholesterol level created_by: jesmith @@ -24517,7 +24517,7 @@ creation_date: 2015-12-03T15:41:10Z [Term] id: CMO:0002697 name: blood lipoprotein phospholipid level -def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in lipoprotein molecules in a specified volume of blood. Lipoprotein particles are complex molecules that consist of a protein membrane surrounding a core of lipids." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine_2008, ISBN:978-1416049982, Website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "Measurement of the amount of phospholipid, any of various phosphorus-containing lipids that are composed mainly of fatty acids, a phosphate group, and a simple organic molecule such as glycerol, carried in lipoprotein molecules in a specified volume of blood. Lipoprotein particles are complex molecules that consist of a protein membrane surrounding a core of lipids." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Gale:Gale_Encyclopedia_of_Medicine_2008, ISBN:978-1416049982, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0000119 ! blood lipoprotein level created_by: jesmith creation_date: 2015-12-03T15:43:06Z @@ -24525,7 +24525,7 @@ creation_date: 2015-12-03T15:43:06Z [Term] id: CMO:0002698 name: urine ketone body level -def: "Measurement of the amount of ketone bodies, that is, acetoacetate, 3-hydroxybutyrate and/or acetone, in a specified sample of urine. Ketone bodies are produced by fatty acid and carbohydrate metabolism and seen in conditions such as fasting, starvation and diabetes mellitus." [Wikipedia:https\://en.wikipedia.org/wiki/Ketone_bodies] +def: "Measurement of the amount of ketone bodies, that is, acetoacetate, 3-hydroxybutyrate and/or acetone, in a specified sample of urine. Ketone bodies are produced by fatty acid and carbohydrate metabolism and seen in conditions such as fasting, starvation and diabetes mellitus." [https://en.wikipedia.org/wiki/Ketone_bodies] is_a: CMO:0000256 ! urine measurement created_by: jesmith creation_date: 2016-04-07T16:57:52Z @@ -24756,7 +24756,7 @@ creation_date: 2017-02-22T13:14:54Z [Term] id: CMO:0002723 name: percent change in pulse pressure -def: "A calculated measurement of the relative difference in pulse pressure between a treated state and a control state or between two points in time, expressed as a percentage." [Wikipedia:http\://en.wikipedia.org/wiki/Percent_change] +def: "A calculated measurement of the relative difference in pulse pressure between a treated state and a control state or between two points in time, expressed as a percentage." [https://en.wikipedia.org/wiki/Percent_change] is_a: CMO:0000292 ! pulse pressure created_by: jesmith creation_date: 2017-02-22T13:28:13Z @@ -24841,7 +24841,7 @@ creation_date: 2017-02-23T18:38:22Z [Term] id: CMO:0002732 name: tibia midshaft cortical thickness -def: "The width of the layer of cortical, compact or cancellous bone (the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level), measured midway between the two epiphyses (that is, the ends) of the bone." [Website:http\://biomech2.me.berkeley.edu/cortical.html] +def: "The width of the layer of cortical, compact or cancellous bone (the relatively solid type of bone tissue found in the middle of long bones which is a hierarchical composite material consisting of a collagen-hydroxyapatite composite at the lowest level forming a complex network of cylindrical units of laminated bone at the highest level), measured midway between the two epiphyses (that is, the ends) of the bone." [http://biomech2.me.berkeley.edu/cortical.html] synonym: "mid-tibia cortical thickness" EXACT [] xref: MA:0001361 is_a: CMO:0002731 ! tibia midshaft morphological measurement @@ -24921,7 +24921,7 @@ creation_date: 2017-07-19T13:04:34Z [Term] id: CMO:0002741 name: heart angiotensin I converting enzyme activity level -def: "Quantitation of the catalytic effect exerted by angiotensin I converting enzyme (ACE) in a specified sample of heart tissue. ACE is one of the enzymes of the renin-angiotensin system, and catalyzes the conversion of angiotensin I into a physiologically active vasoconstrictor peptide angiotensin II." [Wikipedia:https\://en.wikipedia.org/wiki/Angiotensin-converting_enzyme] +def: "Quantitation of the catalytic effect exerted by angiotensin I converting enzyme (ACE) in a specified sample of heart tissue. ACE is one of the enzymes of the renin-angiotensin system, and catalyzes the conversion of angiotensin I into a physiologically active vasoconstrictor peptide angiotensin II." [https://en.wikipedia.org/wiki/Angiotensin-converting_enzyme] synonym: "heart ACE activity level" RELATED [] is_a: CMO:0002739 ! heart enzyme activity level created_by: jesmith @@ -24967,7 +24967,7 @@ creation_date: 2017-07-20T10:00:38Z [Term] id: CMO:0002746 name: kidney angiotensin I converting enzyme activity level -def: "Quantitation of the catalytic effect exerted by angiotensin I converting enzyme (ACE) in a specified sample of kidney tissue. ACE is one of the enzymes of the renin-angiotensin system, and catalyzes the conversion of angiotensin I into a physiologically active vasoconstrictor peptide angiotensin II." [Wikipedia:https\://en.wikipedia.org/wiki/Angiotensin-converting_enzyme] +def: "Quantitation of the catalytic effect exerted by angiotensin I converting enzyme (ACE) in a specified sample of kidney tissue. ACE is one of the enzymes of the renin-angiotensin system, and catalyzes the conversion of angiotensin I into a physiologically active vasoconstrictor peptide angiotensin II." [https://en.wikipedia.org/wiki/Angiotensin-converting_enzyme] synonym: "kidney ACE activity level" RELATED [] is_a: CMO:0002223 ! kidney enzyme activity measurement created_by: jesmith @@ -25011,7 +25011,7 @@ creation_date: 2017-07-20T10:11:08Z [Term] id: CMO:0002751 name: lung angiotensin I converting enzyme activity level -def: "Quantitation of the catalytic effect exerted by angiotensin I converting enzyme (ACE) in a specified sample of lung tissue. ACE is one of the enzymes of the renin-angiotensin system, and catalyzes the conversion of angiotensin I into a physiologically active vasoconstrictor peptide angiotensin II." [Wikipedia:https\://en.wikipedia.org/wiki/Angiotensin-converting_enzyme] +def: "Quantitation of the catalytic effect exerted by angiotensin I converting enzyme (ACE) in a specified sample of lung tissue. ACE is one of the enzymes of the renin-angiotensin system, and catalyzes the conversion of angiotensin I into a physiologically active vasoconstrictor peptide angiotensin II." [https://en.wikipedia.org/wiki/Angiotensin-converting_enzyme] synonym: "lung ACE activity level" RELATED [] is_a: CMO:0002749 ! lung enzyme activity measurement created_by: jesmith @@ -25020,7 +25020,7 @@ creation_date: 2017-07-20T10:12:03Z [Term] id: CMO:0002752 name: congenital malformation incidence/prevalence measurement -def: "Any measurement in which the number of individuals in a study population that display congenital malformation(s) at a point in time or develop congenital malformation(s) within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. Congenital malformations represent a heterogenous group of structural defects, which are usually identified at birth." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:https\://en.wikipedia.org/wiki/Congenital_disorder] +def: "Any measurement in which the number of individuals in a study population that display congenital malformation(s) at a point in time or develop congenital malformation(s) within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. Congenital malformations represent a heterogenous group of structural defects, which are usually identified at birth." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Congenital_disorder] is_a: CMO:0000926 ! disease incidence/prevalence measurement created_by: jesmith creation_date: 2017-07-20T10:55:12Z @@ -25057,7 +25057,7 @@ creation_date: 2017-07-20T13:07:44Z [Term] id: CMO:0002756 name: anogenital distance to cube root of body weight ratio -def: "A calculated value in which anogenital distance (the length of a line between the anal opening and the genitalia) is divided by the cube root of the weight of the body and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Wikipedia:https\://en.wikipedia.org/wiki/Anogenital_distance] +def: "A calculated value in which anogenital distance (the length of a line between the anal opening and the genitalia) is divided by the cube root of the weight of the body and the result presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, https://en.wikipedia.org/wiki/Anogenital_distance] is_a: CMO:0000022 ! calculated body morphological measurement is_a: CMO:0002385 ! anogenital distance created_by: jesmith @@ -25263,7 +25263,7 @@ creation_date: 2017-08-25T16:36:23Z [Term] id: CMO:0002776 name: blood cystatin level -def: "The amount of any cystatin (that is, of any member of the cystatin superfamily of proteins, many of which act as cysteine protease inhibitors) found in a specified sample of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [HGNC:http\://www.genenames.org/cgi-bin/genefamilies/set/964, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed] +def: "The amount of any cystatin (that is, of any member of the cystatin superfamily of proteins, many of which act as cysteine protease inhibitors) found in a specified sample of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [http://www.genenames.org/cgi-bin/genefamilies/set/964, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed] is_a: CMO:0000028 ! blood protein measurement created_by: jesmith creation_date: 2017-08-25T16:43:22Z @@ -25355,7 +25355,7 @@ creation_date: 2018-05-15T16:01:18Z [Term] id: CMO:0002786 name: blood hemoglobin A1c level -def: "The relative concentration of hemoglobin that has been glycosylated as a result of the nonenzymatic attachment of a glucose/hexose moiety to the amino terminal valine of the beta chain of the hemoglobin molecule, in a specified sample of blood." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Website:https\://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/82080] +def: "The relative concentration of hemoglobin that has been glycosylated as a result of the nonenzymatic attachment of a glucose/hexose moiety to the amino terminal valine of the beta chain of the hemoglobin molecule, in a specified sample of blood." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/82080] synonym: "blood glycated hemoglobin level" RELATED [] synonym: "blood glycohemoglobin level" RELATED [] synonym: "blood glycosylated hemoglobin level" RELATED [] @@ -25385,7 +25385,7 @@ creation_date: 2018-05-15T17:02:51Z [Term] id: CMO:0002789 name: E/A wave ratio -def: "A calculated measurement in which the value of the E wave (that is, the velocity of the blood flow across the mitral valve during passive filling of the left ventricle in early diastole) is divided by the value of the A wave (that is, the velocity of the blood flow across the mitral valve during active filling of the left ventricle caused by atrial contraction in late diastole)." [eBook:https\://www.ncbi.nlm.nih.gov/books/NBK2215/, Wikipedia:https\://en.wikipedia.org/wiki/E/A_ratio] +def: "A calculated measurement in which the value of the E wave (that is, the velocity of the blood flow across the mitral valve during passive filling of the left ventricle in early diastole) is divided by the value of the A wave (that is, the velocity of the blood flow across the mitral valve during active filling of the left ventricle caused by atrial contraction in late diastole)." [https://www.ncbi.nlm.nih.gov/books/NBK2215/, https://en.wikipedia.org/wiki/E/A_ratio] synonym: "mitral E/A wave ratio" RELATED [] is_a: CMO:0002788 ! calculated heart blood flow measurement created_by: jrsmith @@ -25636,7 +25636,7 @@ creation_date: 2018-11-14T11:19:47Z [Term] id: CMO:0002818 name: blood type I collagen C-terminal telopeptide level -def: "The amount of type I collagen C-terminal telopeptide in a specified volume of blood. The C-terminal telopeptide can be used as a biomarker in the serum to measure the rate of bone turnover." [Wikipedia:(https\://en.wikipedia.org/wiki/C-terminal_telopeptide] +def: "The amount of type I collagen C-terminal telopeptide in a specified volume of blood. The C-terminal telopeptide can be used as a biomarker in the serum to measure the rate of bone turnover." [https://en.wikipedia.org/wiki/C-terminal_telopeptide] synonym: "blood carboxy-terminal collagen crosslinks" RELATED [] synonym: "blood CTX" RELATED [] is_a: CMO:0000028 ! blood protein measurement @@ -25646,7 +25646,7 @@ creation_date: 2018-11-14T16:11:51Z [Term] id: CMO:0002819 name: plasma type I collagen C-terminal telopeptide level -def: "The amount of type I collagen C-terminal telopeptide in a specified volume of plasma. The C-terminal telopeptide can be used as a biomarker in the serum to measure the rate of bone turnover." [Wikipedia:https\://en.wikipedia.org/wiki/C-terminal_telopeptide] +def: "The amount of type I collagen C-terminal telopeptide in a specified volume of plasma. The C-terminal telopeptide can be used as a biomarker in the serum to measure the rate of bone turnover." [https://en.wikipedia.org/wiki/C-terminal_telopeptide] synonym: "plasma carboxy-terminal collagen crosslinks" RELATED [] synonym: "plasma CTX" RELATED [] is_a: CMO:0002818 ! blood type I collagen C-terminal telopeptide level @@ -25656,7 +25656,7 @@ creation_date: 2018-11-14T16:19:38Z [Term] id: CMO:0002820 name: serum type I collagen C-terminal telopeptide level -def: "The amount of type I collagen C-terminal telopeptide in a specified volume of serum. The C-terminal telopeptide can be used as a biomarker in the serum to measure the rate of bone turnover." [Wikipedia:https\://en.wikipedia.org/wiki/C-terminal_telopeptide] +def: "The amount of type I collagen C-terminal telopeptide in a specified volume of serum. The C-terminal telopeptide can be used as a biomarker in the serum to measure the rate of bone turnover." [https://en.wikipedia.org/wiki/C-terminal_telopeptide] synonym: "serum carboxy-terminal collagen crosslinks" RELATED [] synonym: "serum CTX" RELATED [] is_a: CMO:0002819 ! plasma type I collagen C-terminal telopeptide level @@ -25707,7 +25707,7 @@ creation_date: 2018-11-16T14:08:01Z [Term] id: CMO:0002827 name: neuron cytoplasm measurement -def: "Any quantification of a morphological or physiological parameter of neuron cytoplasm." [Gene Ontology:GO\:0005737, ISBN:ISBN\:0198547684] +def: "Any quantification of a morphological or physiological parameter of neuron cytoplasm." [GO:0005737, ISBN:0198547684] synonym: "neuronal cytoplasm measurement" EXACT [] is_a: CMO:0002826 ! neuron organelle measurement created_by: sjwang @@ -25725,7 +25725,7 @@ creation_date: 2018-11-16T14:19:18Z [Term] id: CMO:0002829 name: neuron mitochondrion measurement -def: "Any quantification of a morphological or physiological parameter of one or more neuronal mitochondria." [Gene Ontology:GO\:0005739, ISBN:ISBN\:0198547684] +def: "Any quantification of a morphological or physiological parameter of one or more neuronal mitochondria." [GO:0005739, ISBN:0198547684] synonym: "neuronal mitochondrion measurement" EXACT [] is_a: CMO:0002826 ! neuron organelle measurement created_by: sjwang @@ -25761,7 +25761,7 @@ creation_date: 2018-11-16T14:35:15Z [Term] id: CMO:0002833 name: neuron lysosome measurement -def: "Any quantification of a morphological or physiological parameter of one or more neuronal lysosomes." [Gene Ontology:GO\:0005764, ISBN:ISBN\:0198547684] +def: "Any quantification of a morphological or physiological parameter of one or more neuronal lysosomes." [GO:0005764, ISBN:0198547684] synonym: "neuronal lysosome measurement" EXACT [] is_a: CMO:0002826 ! neuron organelle measurement created_by: sjwang @@ -25797,7 +25797,7 @@ creation_date: 2018-11-16T14:49:46Z [Term] id: CMO:0002837 name: neuron golgi apparatus measurement -def: "Any quantification of a morphological or physiological parameter of the neuronal golgi apparatus." [Gene Ontology:GO\:0005794, ISBN:ISBN\:0198547684] +def: "Any quantification of a morphological or physiological parameter of the neuronal golgi apparatus." [GO:0005794, ISBN:0198547684] synonym: "neuronal golgi apparatus measurement" EXACT [] is_a: CMO:0002826 ! neuron organelle measurement created_by: sjwang @@ -25833,7 +25833,7 @@ creation_date: 2018-11-16T15:14:47Z [Term] id: CMO:0002841 name: neuron rough endoplasmic reticulum measurement -def: "Any quantification of a morphological or physiological parameter of the neuronal rough endoplasmic reticulum." [Gene Ontology:GO\:0005791, ISBN:ISBN\:0198547684] +def: "Any quantification of a morphological or physiological parameter of the neuronal rough endoplasmic reticulum." [GO:0005791, ISBN:0198547684] synonym: "neuronal rER measurement" EXACT [] synonym: "neuronal rough endoplasmic reticulum measurement" EXACT [] is_a: CMO:0002826 ! neuron organelle measurement @@ -25870,7 +25870,7 @@ creation_date: 2018-11-16T15:38:07Z [Term] id: CMO:0002845 name: neuron vacuole measurement -def: "Any quantification of a morphological or physiological parameter of the neuronal vacuole." [Gene Ontology:GO\:0005773, ISBN:ISBN\:0198547684] +def: "Any quantification of a morphological or physiological parameter of the neuronal vacuole." [GO:0005773, ISBN:0198547684] synonym: "neuronal vacuole measurement" EXACT [] is_a: CMO:0002826 ! neuron organelle measurement created_by: sjwang @@ -25959,7 +25959,7 @@ creation_date: 2018-11-19T16:02:40Z [Term] id: CMO:0002855 name: blood fructosamine level -def: "The amount of fructosamine, the compound that results from glycation reactions between a sugar and a primary amine, followed by isomerization via the Amadori rearrangement, found in a specific volume of blood" [Wikipedia:https\://en.wikipedia.org/wiki/Fructosamine] +def: "The amount of fructosamine, the compound that results from glycation reactions between a sugar and a primary amine, followed by isomerization via the Amadori rearrangement, found in a specific volume of blood" [https://en.wikipedia.org/wiki/Fructosamine] is_a: CMO:0000023 ! blood chemistry measurement created_by: sjwang creation_date: 2018-11-19T16:06:07Z @@ -25999,7 +25999,7 @@ creation_date: 2018-11-21T12:35:22Z [Term] id: CMO:0002860 name: Monophasic action potential -def: "Monophasic action potentials (MAPs) are recorded using contact electrode catheters. The recordings provide local information about the actual cellular depolarization and repolarization process of myocardial tissue. They are different from body surface electrocardiographic (ECG) recordings or standard endocardial electrograms, which produce a summative or derivative view of the heart's electrical activity" [ISBN:ISBN\: 978-1-4557-2856-5, ZIPES:Zipes_Cardiac Electrophysiology\: From Cell to Bedside (Sixth Edition)] +def: "Monophasic action potentials (MAPs) are recorded using contact electrode catheters. The recordings provide local information about the actual cellular depolarization and repolarization process of myocardial tissue. They are different from body surface electrocardiographic (ECG) recordings or standard endocardial electrograms, which produce a summative or derivative view of the heart's electrical activity" [ISBN:978-1-4557-2856-5, ZIPES:Zipes_Cardiac Electrophysiology\: From Cell to Bedside (Sixth Edition)] is_a: CMO:0000230 ! heart electrical conduction measurement created_by: sjwang creation_date: 2018-11-26T13:03:49Z @@ -26007,7 +26007,7 @@ creation_date: 2018-11-26T13:03:49Z [Term] id: CMO:0002861 name: Conduction velocity -def: "Conduction velocity is calculated as the distance from pacing electrode to the monophasic action potential recording electrode across the epicardial surface, divided by the conduction time, the time from the pacing spike to monophasic action potential onset." [XREF:PMID\:17322641] +def: "Conduction velocity is calculated as the distance from pacing electrode to the monophasic action potential recording electrode across the epicardial surface, divided by the conduction time, the time from the pacing spike to monophasic action potential onset." [PMID:17322641] is_a: CMO:0000230 ! heart electrical conduction measurement created_by: sjwang creation_date: 2018-11-26T13:39:11Z @@ -26140,7 +26140,7 @@ creation_date: 2018-11-27T13:20:33Z [Term] id: CMO:0002876 name: Blood NH2-terminal pro-B-type natriuretic peptide level -def: "The amount of N-terminal (NT)-pro hormone BNP (Nppb) in a specified volume of blood." [XREF:https\://rgd.mcw.edu/rgdweb/report/gene/main.html?id=3194] +def: "The amount of N-terminal (NT)-pro hormone BNP (Nppb) in a specified volume of blood." [https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=3194] synonym: "Blood NH2-terminal Nppb level" EXACT [] is_a: CMO:0000286 ! blood peptide hormone level created_by: sjwang @@ -26213,7 +26213,7 @@ creation_date: 2018-11-27T15:20:50Z [Term] id: CMO:0002885 name: arterial elastance -def: "Effective arterial elastance (Ea), defined as the ratio of left ventricular (LV) end-systolic pressure and stroke volume, lumps the steady and pulsatile components of the arterial load in a concise way." [PMID:PMID\:11834502] +def: "Effective arterial elastance (Ea), defined as the ratio of left ventricular (LV) end-systolic pressure and stroke volume, lumps the steady and pulsatile components of the arterial load in a concise way." [PMID:11834502] is_a: CMO:0002884 ! calculated left ventricular end-systolic blood pressure created_by: sjwang creation_date: 2018-11-27T15:23:57Z @@ -26221,7 +26221,7 @@ creation_date: 2018-11-27T15:23:57Z [Term] id: CMO:0002886 name: ventricle stroke work -def: "Defined as the work performed by the left or right ventricle to eject the stroke volume into the aorta or pulmonary artery, respectively." [Wikipedia:https\://en.wikipedia.org/wiki/Pressure%E2%80%93volume_loop_analysis_in_cardiology] +def: "Defined as the work performed by the left or right ventricle to eject the stroke volume into the aorta or pulmonary artery, respectively." [https://en.wikipedia.org/wiki/Pressure%E2%80%93volume_loop_analysis_in_cardiology] is_a: CMO:0000981 ! ventricle contraction measurement created_by: sjwang creation_date: 2018-11-27T15:29:19Z @@ -26229,7 +26229,7 @@ creation_date: 2018-11-27T15:29:19Z [Term] id: CMO:0002887 name: left ventricle stroke work -def: "Defined as the work performed by the left ventricle to eject the stroke volume into the aorta." [Wikipedia:https\://en.wikipedia.org/wiki/Pressure%E2%80%93volume_loop_analysis_in_cardiology] +def: "Defined as the work performed by the left ventricle to eject the stroke volume into the aorta." [https://en.wikipedia.org/wiki/Pressure%E2%80%93volume_loop_analysis_in_cardiology] is_a: CMO:0002886 ! ventricle stroke work created_by: sjwang creation_date: 2018-11-27T15:32:24Z @@ -26237,7 +26237,7 @@ creation_date: 2018-11-27T15:32:24Z [Term] id: CMO:0002888 name: preload recruitable left ventricle stroke work -def: "Preload recruitable stroke work (PRSW) is determined by the linear regression of stroke work with the end-diastolic volume. The slope of the PRSW relationship is a highly linear index of myocardial contractility that is insensitive to preload and afterload." [Wikipedia:https\://en.wikipedia.org/wiki/Pressure%E2%80%93volume_loop_analysis_in_cardiology] +def: "Preload recruitable stroke work (PRSW) is determined by the linear regression of stroke work with the end-diastolic volume. The slope of the PRSW relationship is a highly linear index of myocardial contractility that is insensitive to preload and afterload." [https://en.wikipedia.org/wiki/Pressure%E2%80%93volume_loop_analysis_in_cardiology] is_a: CMO:0002887 ! left ventricle stroke work created_by: sjwang creation_date: 2018-11-27T15:34:52Z @@ -26358,7 +26358,7 @@ creation_date: 2018-11-30T15:51:29Z [Term] id: CMO:0002903 name: renal medullary blood flow rate -def: "Renal medullary blood flow (MBF) is the volume of blood delivered to or exiting from the renal medulla per unit time." [PMID:PMID\: 22080855] +def: "Renal medullary blood flow (MBF) is the volume of blood delivered to or exiting from the renal medulla per unit time." [PMID:22080855] is_a: CMO:0000907 ! renal blood flow rate created_by: sjwang creation_date: 2018-11-30T15:55:22Z @@ -26366,7 +26366,7 @@ creation_date: 2018-11-30T15:55:22Z [Term] id: CMO:0002904 name: blood vasopressin level -def: "The amount of vasopressin in a specified volume of blood. Vasopressin belongs to family of cyclic nonapeptide hormones found in most mammals. Synthesised in the hypothalamus and stored in the post-pituitary, vasopressins play a key role in homeostasis, particularly in regulating the body's water content. Together with the similar neuropeptide oxytocin, they are believed to influence social cognition and behaviour" [CHEBI:CHEBI\:9937] +def: "The amount of vasopressin in a specified volume of blood. Vasopressin belongs to family of cyclic nonapeptide hormones found in most mammals. Synthesised in the hypothalamus and stored in the post-pituitary, vasopressins play a key role in homeostasis, particularly in regulating the body's water content. Together with the similar neuropeptide oxytocin, they are believed to influence social cognition and behaviour" [CHEBI:9937] is_a: CMO:0000286 ! blood peptide hormone level created_by: sjwang creation_date: 2018-12-03T14:09:44Z @@ -26522,7 +26522,7 @@ creation_date: 2018-12-06T15:46:50Z [Term] id: CMO:0002923 name: plasma osmolality -def: "The number of dissolved particles in a specified volume of plasma." [Wikipedia:https\://en.wikipedia.org/wiki/Plasma_osmolality] +def: "The number of dissolved particles in a specified volume of plasma." [https://en.wikipedia.org/wiki/Plasma_osmolality] is_a: CMO:0000023 ! blood chemistry measurement created_by: sjwang creation_date: 2018-12-06T16:05:07Z @@ -26714,7 +26714,7 @@ creation_date: 2018-12-07T14:54:49Z [Term] id: CMO:0002946 name: single nephron filtration fraction -def: "A calculated measurement to determine the ratio of the single nephron glomerular filtration rate (SNGFR) to the renal plasma flow (RPF). Single nephron filtration Fraction, SNFF = SNGFR/RPF. The single nephron filtration fraction, therefore, represents the proportion of the fluid reaching the kidneys which passes into the renal tubules from a single nephron." [Wikipedia:Source\:https\://en.wikipedia.org/wiki/Filtration_fraction] +def: "A calculated measurement to determine the ratio of the single nephron glomerular filtration rate (SNGFR) to the renal plasma flow (RPF). Single nephron filtration Fraction, SNFF = SNGFR/RPF. The single nephron filtration fraction, therefore, represents the proportion of the fluid reaching the kidneys which passes into the renal tubules from a single nephron." [https://en.wikipedia.org/wiki/Filtration_fraction] synonym: "SNFF" EXACT [] is_a: CMO:0001917 ! calculated renal plasma flow is_a: CMO:0002945 ! single nephron glomerular filtration rate @@ -26731,7 +26731,7 @@ creation_date: 2018-12-07T15:14:18Z [Term] id: CMO:0002948 name: renal tubulointerstitial score -def: ""A semiquantitative evaluation of the renal interstitium using a grading system with a score of 0 to 4+, which assesses the tubules and the interstitium for the presence of (1) tubular atrophy, (2) tubular dilatation, (3) interstitial inflammatory cell infiltrates, and (4) interstitial fibrosis. A score of 0 indicates no lesion (normal kidney), 1+ indicates a single, small focal lesion with very minimal tubular alterations and interstitial inflammatory cell infiltration, and 2+ to 4+ indicated increasing severity of tubular lesions, interstitial inflammatory cell infiltration, and/or fibrosis. A score of 4+ indicates involvement of approximately 50% or more of the renal parenchyma or interstitium." [PMID:PMID\:9369281] +def: ""A semiquantitative evaluation of the renal interstitium using a grading system with a score of 0 to 4+, which assesses the tubules and the interstitium for the presence of (1) tubular atrophy, (2) tubular dilatation, (3) interstitial inflammatory cell infiltrates, and (4) interstitial fibrosis. A score of 0 indicates no lesion (normal kidney), 1+ indicates a single, small focal lesion with very minimal tubular alterations and interstitial inflammatory cell infiltration, and 2+ to 4+ indicated increasing severity of tubular lesions, interstitial inflammatory cell infiltration, and/or fibrosis. A score of 4+ indicates involvement of approximately 50% or more of the renal parenchyma or interstitium." [PMID:9369281] synonym: "kidney tubulointerstitial score" EXACT [] is_a: CMO:0002947 ! calculated kidney morphological measurement created_by: sjwang @@ -26828,7 +26828,7 @@ creation_date: 2018-12-26T16:17:20Z [Term] id: CMO:0002960 name: mesangial injury score -def: "An injury score obtained by multiplying the degree of glomerular damage (0 to 4) with the percentage of the glomeruli with that type of injury (i.e., increase in mesangial matrix material or glomerulosclerosis)." [PMID:PMID\:9841488] +def: "An injury score obtained by multiplying the degree of glomerular damage (0 to 4) with the percentage of the glomeruli with that type of injury (i.e., increase in mesangial matrix material or glomerulosclerosis)." [PMID:9841488] is_a: CMO:0001135 ! index of glomerular damage created_by: sjwang creation_date: 2018-12-26T16:20:07Z @@ -26860,7 +26860,7 @@ creation_date: 2018-12-26T16:27:55Z [Term] id: CMO:0002964 name: tibialis anterior muscle weight -def: "The weight or the measure of the heaviness of tibialis anterior muscle, which is a muscle that originates in the upper two-thirds of the lateral surface of the tibia and inserts into the medial cuneiform and first metatarsal bones of the foot. Its acts to invert the foot. It is situated on the lateral side of the tibia; it is thick and fleshy above, tendinous below. This muscle overlaps the anterior tibial vessels and deep peroneal nerve in the upper part of the leg." [UBERON:UBERON\:0001385] +def: "The weight or the measure of the heaviness of tibialis anterior muscle, which is a muscle that originates in the upper two-thirds of the lateral surface of the tibia and inserts into the medial cuneiform and first metatarsal bones of the foot. Its acts to invert the foot. It is situated on the lateral side of the tibia; it is thick and fleshy above, tendinous below. This muscle overlaps the anterior tibial vessels and deep peroneal nerve in the upper part of the leg." [UBERON:0001385] is_a: CMO:0001148 ! skeletal muscle weight created_by: sjwang creation_date: 2018-12-26T16:39:22Z @@ -26868,7 +26868,7 @@ creation_date: 2018-12-26T16:39:22Z [Term] id: CMO:0002965 name: extensor digitorum longus muscle weight -def: "The weight or the measure of the heaviness of extensor digitorum longus muscle, which is a penniform muscle of the lateral front part of the hindlimb responsible for extension of the digits and dorsiflexion of the ankle." [UBERON:UBERON\:0001386] +def: "The weight or the measure of the heaviness of extensor digitorum longus muscle, which is a penniform muscle of the lateral front part of the hindlimb responsible for extension of the digits and dorsiflexion of the ankle." [UBERON:0001386] is_a: CMO:0001148 ! skeletal muscle weight created_by: sjwang creation_date: 2018-12-27T09:53:38Z @@ -26920,7 +26920,7 @@ creation_date: 2018-12-27T12:03:45Z [Term] id: CMO:0002971 name: arteriolar resistance -def: "Resistance that must be overcome to push blood through arterioles to create flow." [Wikipedia:https\://en.wikipedia.org/wiki/Vascular_resistance] +def: "Resistance that must be overcome to push blood through arterioles to create flow." [https://en.wikipedia.org/wiki/Vascular_resistance] is_a: CMO:0000700 ! blood vessel resistance measurement is_a: CMO:0002970 ! arteriole measurement created_by: sjwang @@ -26981,7 +26981,7 @@ creation_date: 2018-12-27T12:49:32Z [Term] id: CMO:0002977 name: afferent colloid osmotic pressure -def: "A form of osmotic pressure exerted by proteins, notably albumin, in the afferent arteriole's plasma that tends to pull water into the circulatory system. It is the opposing force to hydrostatic pressure. It has a major effect on the pressure across the glomerular filter." [Wikipedia:http\://en.wikipedia.org/wiki/Osmotic_pressure] +def: "A form of osmotic pressure exerted by proteins, notably albumin, in the afferent arteriole's plasma that tends to pull water into the circulatory system. It is the opposing force to hydrostatic pressure. It has a major effect on the pressure across the glomerular filter." [https://en.wikipedia.org/wiki/Osmotic_pressure] is_a: CMO:0002970 ! arteriole measurement created_by: sjwang creation_date: 2018-12-27T12:53:15Z @@ -26989,7 +26989,7 @@ creation_date: 2018-12-27T12:53:15Z [Term] id: CMO:0002978 name: efferent colloid osmotic pressure -def: "A form of osmotic pressure exerted by proteins, notably albumin, in the efferent arteriole's plasma that tends to pull water into the circulatory system. It is the opposing force to hydrostatic pressure. It has a major effect on the pressure across the glomerular filter" [Wikipedia:http\://en.wikipedia.org/wiki/Osmotic_pressure] +def: "A form of osmotic pressure exerted by proteins, notably albumin, in the efferent arteriole's plasma that tends to pull water into the circulatory system. It is the opposing force to hydrostatic pressure. It has a major effect on the pressure across the glomerular filter" [https://en.wikipedia.org/wiki/Osmotic_pressure] is_a: CMO:0002970 ! arteriole measurement created_by: sjwang creation_date: 2018-12-27T13:07:24Z @@ -26997,7 +26997,7 @@ creation_date: 2018-12-27T13:07:24Z [Term] id: CMO:0002979 name: glomerular capillary ultrafiltration coefficient -def: "A measure of a membrane's permeability to water; specifically, the volume of fluid filtered in unit time through a unit area of membrane per unit pressure difference, and it is defined as the glomerular filtration rate (GFR) for both kidneys per millimeter of mercury (mmHg) of filtration pressure." [Wikipedia:https\://en.wikipedia.org/wiki/Filtration_coefficient] +def: "A measure of a membrane's permeability to water; specifically, the volume of fluid filtered in unit time through a unit area of membrane per unit pressure difference, and it is defined as the glomerular filtration rate (GFR) for both kidneys per millimeter of mercury (mmHg) of filtration pressure." [https://en.wikipedia.org/wiki/Filtration_coefficient] synonym: "Kf" EXACT [] is_a: CMO:0000490 ! blood glomerular filtration rate created_by: sjwang @@ -27171,7 +27171,7 @@ creation_date: 2019-01-04T16:28:41Z [Term] id: CMO:0003000 name: blood insulin level AUC to blood glucose level AUC ratio -def: "The calculated value blood insulin level area under curve divided by the calculated blood glucose level area under curve. Area under the curve for blood glucose or insulin is a value in which a series of measurements of the amount of insulin or glucose in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Dorland:Dorland\:Dorlands_Illustrated_Medical_Dictionary--31st_Ed\, ISBN\:978-1416049982] +def: "The calculated value blood insulin level area under curve divided by the calculated blood glucose level area under curve. Area under the curve for blood glucose or insulin is a value in which a series of measurements of the amount of insulin or glucose in a specified volume of blood is plotted against time for a single individual and the extent of the two dimensional region bounded by the curve and the axes of the graph is determined." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982] is_a: CMO:0000350 ! blood glucose level area under curve (AUC) is_a: CMO:0000351 ! blood insulin level area under curve (AUC) created_by: sjwang @@ -27180,7 +27180,7 @@ creation_date: 2019-01-22T13:52:17Z [Term] id: CMO:0003001 name: whole body insulin sensitivity index -def: "A calculated measurement to estimate the effect of insulin on net glucose disposal (insulin sensitivity) in an organism, calculated as 10000/(sqaure root of ((fasting glucose x fasting insulin) x (mean glucose across duration of glucose tolerance test x mean insulin across duration of glucose tolerance test)." [PMID:PMID\: 22378939] +def: "A calculated measurement to estimate the effect of insulin on net glucose disposal (insulin sensitivity) in an organism, calculated as 10000/(sqaure root of ((fasting glucose x fasting insulin) x (mean glucose across duration of glucose tolerance test x mean insulin across duration of glucose tolerance test)." [PMID:22378939] synonym: "WBISI" RELATED [] is_a: CMO:0000352 ! calculated blood glucose level is_a: CMO:0000353 ! calculated blood insulin level @@ -27190,7 +27190,7 @@ creation_date: 2019-01-22T14:17:38Z [Term] id: CMO:0003002 name: Homeostatic Model Assessment of Insulin Resistance -def: "Calculated model of insulin resistance where the product of fasting glucose and fasting insulin is divided by 22.5. Glucose is measured in mmol/L and insulin in measured in uIU/ml." [PMID:PMID\:11874940] +def: "Calculated model of insulin resistance where the product of fasting glucose and fasting insulin is divided by 22.5. Glucose is measured in mmol/L and insulin in measured in uIU/ml." [PMID:11874940] synonym: "HOMA-IR" EXACT [] is_a: CMO:0000352 ! calculated blood glucose level is_a: CMO:0000353 ! calculated blood insulin level @@ -27200,7 +27200,7 @@ creation_date: 2019-01-22T14:21:46Z [Term] id: CMO:0003003 name: blood hesperetin level -def: "The amount of hesperetin found in a specified volume of blood. Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside Hesperidin, is the predominant flavonoid in lemons and oranges." [Drugbank:https\://www.drugbank.ca/drugs/DB01094] +def: "The amount of hesperetin found in a specified volume of blood. Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside Hesperidin, is the predominant flavonoid in lemons and oranges." [https://www.drugbank.ca/drugs/DB01094] synonym: "CHEBI:28230" RELATED [] is_a: CMO:0002466 ! blood xenobiotic level created_by: sjwang @@ -27209,7 +27209,7 @@ creation_date: 2019-01-22T14:26:37Z [Term] id: CMO:0003004 name: plasma hesperetin level -def: "The amount of hesperetin found in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended.Hesperetin, in the form of its glycoside Hesperidin, is the predominant flavonoid in lemons and oranges." [Drugbank:https\://www.drugbank.ca/drugs/DB01094] +def: "The amount of hesperetin found in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended.Hesperetin, in the form of its glycoside Hesperidin, is the predominant flavonoid in lemons and oranges." [https://www.drugbank.ca/drugs/DB01094] synonym: "CHEBI:28230" RELATED [] is_a: CMO:0003003 ! blood hesperetin level created_by: sjwang @@ -27218,7 +27218,7 @@ creation_date: 2019-01-22T14:46:05Z [Term] id: CMO:0003005 name: serum hesperetin level -def: "The amount of hesperetin found in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Hesperetin, in the form of its glycoside Hesperidin, is the predominant flavonoid in lemons and oranges." [Drugbank:https\://www.drugbank.ca/drugs/DB01094] +def: "The amount of hesperetin found in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Hesperetin, in the form of its glycoside Hesperidin, is the predominant flavonoid in lemons and oranges." [https://www.drugbank.ca/drugs/DB01094] synonym: "CHEBI:28230" RELATED [] is_a: CMO:0003003 ! blood hesperetin level created_by: sjwang @@ -27251,7 +27251,7 @@ creation_date: 2019-01-22T15:11:43Z [Term] id: CMO:0003009 name: serum high density lipoprotein cholesterol level to serum total cholesterol level ratio -def: "A calculated measurement in which the amount of HDL cholesterol in a specified volume of serum is divided by the amount of total serum cholesterol, without taking into account any association with other molecules such as lipoproteins, in a specified volume of serum, in the same sample, and presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed\, ISBN\:978-1416049982, website:http\://themedicalbiochemistrypage.org/lipoproteins.php] +def: "A calculated measurement in which the amount of HDL cholesterol in a specified volume of serum is divided by the amount of total serum cholesterol, without taking into account any association with other molecules such as lipoproteins, in a specified volume of serum, in the same sample, and presented as a ratio, fraction, quotient or percentage." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, http://themedicalbiochemistrypage.org/lipoproteins.php] is_a: CMO:0000363 ! serum total cholesterol level is_a: CMO:0003008 ! calculated serum high density lipoprotein cholesterol level created_by: sjwang @@ -27302,7 +27302,7 @@ creation_date: 2019-01-22T15:50:45Z [Term] id: CMO:0003015 name: gastrointestinal morphological measurement -def: "Measurement of the morphological characteristics of the gastrointestinal tract. The gastrointestinal tract is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces. The mouth, esophagus, stomach and intestines are part of the gastrointestinal tract." [Wikipedia:https\://en.wikipedia.org/wiki/Gastrointestinal_tract] +def: "Measurement of the morphological characteristics of the gastrointestinal tract. The gastrointestinal tract is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces. The mouth, esophagus, stomach and intestines are part of the gastrointestinal tract." [https://en.wikipedia.org/wiki/Gastrointestinal_tract] is_a: CMO:0000068 ! organ morphological measurement created_by: sjwang creation_date: 2019-01-22T15:53:54Z @@ -27310,7 +27310,7 @@ creation_date: 2019-01-22T15:53:54Z [Term] id: CMO:0003016 name: gastrointestinal weight -def: "Measurement of the weight or heaviness of the gastrointestinal tract, that is, the degree to which it is drawn toward the earth by gravity. The gastrointestinal tract is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces. The mouth, esophagus, stomach and intestines are part of the gastrointestinal tract." [Wikipedia:https\://en.wikipedia.org/wiki/Gastrointestinal_tract] +def: "Measurement of the weight or heaviness of the gastrointestinal tract, that is, the degree to which it is drawn toward the earth by gravity. The gastrointestinal tract is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces. The mouth, esophagus, stomach and intestines are part of the gastrointestinal tract." [https://en.wikipedia.org/wiki/Gastrointestinal_tract] synonym: "gastrointestinal tract weight measurement" RELATED [] is_a: CMO:0003015 ! gastrointestinal morphological measurement created_by: sjwang @@ -27363,7 +27363,7 @@ creation_date: 2019-01-29T14:43:08Z [Term] id: CMO:0003022 name: hemoglobin distribution width -def: "The distribution width of erythrocytes by their cellular (individual) hemoglobin concentrations. It is a measurement of the heterogeneity of the red cell hemoglobin concentration." [PMID:PMID\:3411196] +def: "The distribution width of erythrocytes by their cellular (individual) hemoglobin concentrations. It is a measurement of the heterogeneity of the red cell hemoglobin concentration." [PMID:3411196] synonym: "HDW" EXACT [] is_a: CMO:0000508 ! hemoglobin measurement created_by: sjwang @@ -27372,7 +27372,7 @@ creation_date: 2019-01-29T15:15:44Z [Term] id: CMO:0003023 name: urine sorbital dehydrogenase level -def: "The amount of sorbital dehydrogenase in a specific volume of urine. Sorbitol dehydrogenase is an enzyme in carbohydrate metabolism converting sorbitol, the sugar alcohol form of glucose, into fructose." [Wikipedia:https\://en.wikipedia.org/wiki/Sorbitol_dehydrogenase] +def: "The amount of sorbital dehydrogenase in a specific volume of urine. Sorbitol dehydrogenase is an enzyme in carbohydrate metabolism converting sorbitol, the sugar alcohol form of glucose, into fructose." [https://en.wikipedia.org/wiki/Sorbitol_dehydrogenase] is_a: CMO:0000592 ! urine enzyme level created_by: sjwang creation_date: 2019-01-29T15:31:14Z @@ -27397,7 +27397,7 @@ creation_date: 2019-01-29T15:41:36Z [Term] id: CMO:0003026 name: serum total bile acid -def: "The amount of bile acid in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Bile acid is any member of a group of hydroxy-5beta-cholanic acids concurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." [CHEBI:CHEBI\:3098] +def: "The amount of bile acid in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Bile acid is any member of a group of hydroxy-5beta-cholanic acids concurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." [CHEBI:3098] is_a: CMO:0002049 ! serum sterol level created_by: sjwang creation_date: 2019-02-01T09:39:58Z @@ -27431,7 +27431,7 @@ creation_date: 2019-02-14T14:07:14Z [Term] id: CMO:0003030 name: blood galanin level -def: "The amount of galanin in a specified sample of blood. Galanin is a neuropeptide encoded by the Gal gene, that is widely expressed in the brain, spinal cord, and gut of humans as well as other mammals." [Wikipedia:https\://en.wikipedia.org/wiki/Galanin] +def: "The amount of galanin in a specified sample of blood. Galanin is a neuropeptide encoded by the Gal gene, that is widely expressed in the brain, spinal cord, and gut of humans as well as other mammals." [https://en.wikipedia.org/wiki/Galanin] is_a: CMO:0000028 ! blood protein measurement created_by: sjwang creation_date: 2019-02-14T14:39:25Z @@ -27447,7 +27447,7 @@ creation_date: 2019-02-14T14:44:20Z [Term] id: CMO:0003032 name: blood lutenizing hormone level -def: "Measurement of the amount in blood of lutenizing hormone (LH) produced by gonadotropic cells in the anterior pituitary gland. In females, an acute rise of LH triggers ovulation and development of the corpus luteum. In males, LH stimulates Leydig cell production of testosterone." [Wikipedia:https\://en.wikipedia.org/wiki/Luteinizing_hormone] +def: "Measurement of the amount in blood of lutenizing hormone (LH) produced by gonadotropic cells in the anterior pituitary gland. In females, an acute rise of LH triggers ovulation and development of the corpus luteum. In males, LH stimulates Leydig cell production of testosterone." [https://en.wikipedia.org/wiki/Luteinizing_hormone] is_a: CMO:0001003 ! blood hormone level created_by: sjwang creation_date: 2019-02-15T09:29:17Z @@ -27463,7 +27463,7 @@ creation_date: 2019-02-15T09:36:01Z [Term] id: CMO:0003034 name: blood plasminogen activator inhibitor 1 level -def: "a measurement of the amount of plasminogen activator inhibitor 1 (PAI-1)in the blood. PAI-1 is a serine protease inhibitor protein that functions as the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots)." [Wikipedia:https\://en.wikipedia.org/wiki/Plasminogen_activator_inhibitor-1] +def: "a measurement of the amount of plasminogen activator inhibitor 1 (PAI-1)in the blood. PAI-1 is a serine protease inhibitor protein that functions as the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots)." [https://en.wikipedia.org/wiki/Plasminogen_activator_inhibitor-1] is_a: CMO:0000028 ! blood protein measurement created_by: sjwang creation_date: 2019-02-15T10:09:09Z @@ -27883,7 +27883,7 @@ creation_date: 2019-03-19T16:40:31Z [Term] id: CMO:0003087 name: stress-related movement measurement -def: "Any measurable or observable characteristic of actions or reactions related to how the body reacts to a stressor (a stimulus that causes stress), real or imagined." [VT:VT\:0010451] +def: "Any measurable or observable characteristic of actions or reactions related to how the body reacts to a stressor (a stimulus that causes stress), real or imagined." [VT:0010451] is_a: CMO:0000954 ! voluntary body movement measurement created_by: sjwang creation_date: 2019-03-28T15:59:44Z @@ -27899,7 +27899,7 @@ creation_date: 2019-03-28T16:04:15Z [Term] id: CMO:0003089 name: number of periods of licking the abdomen -def: "number of distinct, separable periods of time animals are licking the abdomen in response to stressors during a period of time." [PMID:PMID\:11376906] +def: "number of distinct, separable periods of time animals are licking the abdomen in response to stressors during a period of time." [PMID:11376906] is_a: CMO:0003087 ! stress-related movement measurement created_by: sjwang creation_date: 2019-03-28T16:07:45Z @@ -27907,7 +27907,7 @@ creation_date: 2019-03-28T16:07:45Z [Term] id: CMO:0003090 name: number of abdominal retraction -def: "The number of abdominal retraction in specified period. Abdominal retraction is the contraction of the abdominal wall such that an `arched' posture was observed for a specified time." [PMID:PMID\: 11376906] +def: "The number of abdominal retraction in specified period. Abdominal retraction is the contraction of the abdominal wall such that an `arched' posture was observed for a specified time." [PMID:11376906] is_a: CMO:0003087 ! stress-related movement measurement created_by: sjwang creation_date: 2019-03-28T16:32:33Z @@ -27976,7 +27976,7 @@ creation_date: 2019-04-03T14:03:58Z [Term] id: CMO:0003099 name: comprehensive metabolic panel -def: "The comprehensive metabolic panel (CMP) is a panel of 14 blood tests which serves as an initial broad medical screening tool. The CMP provides a rough check of kidney function, liver function, diabetic and parathyroid status, and electrolyte and fluid balance." [Wikipedia:https\://en.wikipedia.org/wiki/Comprehensive_metabolic_panel] +def: "The comprehensive metabolic panel (CMP) is a panel of 14 blood tests which serves as an initial broad medical screening tool. The CMP provides a rough check of kidney function, liver function, diabetic and parathyroid status, and electrolyte and fluid balance." [https://en.wikipedia.org/wiki/Comprehensive_metabolic_panel] synonym: "basic metabolic panel, BMP" RELATED [] synonym: "chemical screen" EXACT [] is_a: CMO:0000035 ! blood measurement @@ -28243,7 +28243,7 @@ creation_date: 2019-04-23T14:07:41Z [Term] id: CMO:0003133 name: elimination half life of nifedipine in the plasma -def: "The time it takes for the body to eliminate or breakdown half of a dose of a pharmacologic agent, in practice the time taken for plasma concentration to reduce by 50%." [MI:MI\:2049] +def: "The time it takes for the body to eliminate or breakdown half of a dose of a pharmacologic agent, in practice the time taken for plasma concentration to reduce by 50%." [MI:2049] synonym: "elimination half-time" RELATED [] synonym: "T 1/2" EXACT [] is_a: CMO:0003159 ! blood nifedipine metabolism measurement @@ -28308,7 +28308,7 @@ creation_date: 2019-04-23T15:00:17Z [Term] id: CMO:0003141 name: volume of distribution of nifedipine in the blood -def: "In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma. It is defined as the distribution of a medication between plasma and the rest of the body after oral or parenteral dosing." [Wikipedia:https\://en.wikipedia.org/wiki/Volume_of_distribution] +def: "In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma. It is defined as the distribution of a medication between plasma and the rest of the body after oral or parenteral dosing." [https://en.wikipedia.org/wiki/Volume_of_distribution] synonym: "apparent volume of distribution" EXACT [] is_a: CMO:0003159 ! blood nifedipine metabolism measurement created_by: sjwang @@ -28371,7 +28371,7 @@ creation_date: 2019-04-29T14:43:59Z [Term] id: CMO:0003149 name: Trachea lumen circumference -def: "the measurement of the the enclosing boundary of trachea lined by apical surface of epithelium." [PMID:PMID\:24608905] +def: "the measurement of the the enclosing boundary of trachea lined by apical surface of epithelium." [PMID:24608905] is_a: CMO:0003148 ! trachea morphological measurement created_by: sjwang creation_date: 2019-04-29T14:51:33Z @@ -28379,7 +28379,7 @@ creation_date: 2019-04-29T14:51:33Z [Term] id: CMO:0003150 name: Trachea cartiledge area -def: "The measurement of total cartilage area in the tracheal ring." [PMID:PMID\:24608905] +def: "The measurement of total cartilage area in the tracheal ring." [PMID:24608905] is_a: CMO:0003148 ! trachea morphological measurement created_by: sjwang creation_date: 2019-04-29T15:10:35Z @@ -28402,7 +28402,7 @@ creation_date: 2019-04-29T15:24:56Z [Term] id: CMO:0003153 name: Maximum cartilage thickness -def: "Maximal cartilage thickness was evaluated by determining the perpendicular distance between outer boundaries of cartilage rings.." [PMID:PMID\:24608905] +def: "Maximal cartilage thickness was evaluated by determining the perpendicular distance between outer boundaries of cartilage rings.." [PMID:24608905] is_a: CMO:0003148 ! trachea morphological measurement created_by: sjwang creation_date: 2019-04-29T15:31:31Z @@ -28410,7 +28410,7 @@ creation_date: 2019-04-29T15:31:31Z [Term] id: CMO:0003154 name: Trachea epitelial layer thickness -def: "measurement of the distance between the basement membrane (on the serosal surface) and the apical membrane lumenally." [PMID:PMID\:24608905] +def: "measurement of the distance between the basement membrane (on the serosal surface) and the apical membrane lumenally." [PMID:24608905] is_a: CMO:0003148 ! trachea morphological measurement created_by: sjwang creation_date: 2019-04-29T15:51:01Z @@ -28418,7 +28418,7 @@ creation_date: 2019-04-29T15:51:01Z [Term] id: CMO:0003155 name: trachea submucosal gland area -def: "Submucosal gland area was determined by measuring both serous and mucus components of the gland structures." [PMID:PMID\:24608905] +def: "Submucosal gland area was determined by measuring both serous and mucus components of the gland structures." [PMID:24608905] is_a: CMO:0003148 ! trachea morphological measurement created_by: sjwang creation_date: 2019-04-29T15:58:14Z @@ -28441,7 +28441,7 @@ creation_date: 2019-04-29T16:11:39Z [Term] id: CMO:0003158 name: intracellular mucus to total trachea submucosal gland area ratio -def: "The percent of intracellular mucus was determined as the ratio of intracellular mucus/total submucosal gland area." [PMID:PMID\:24608905] +def: "The percent of intracellular mucus was determined as the ratio of intracellular mucus/total submucosal gland area." [PMID:24608905] synonym: "percent of intracellular mucus" RELATED [] is_a: CMO:0003152 ! calculated trachea morphological measurement created_by: sjwang @@ -28540,7 +28540,7 @@ creation_date: 2019-05-22T11:44:04Z [Term] id: CMO:0003170 name: verapamil apparent influx permeability clearance in brain barrier -def: "A fractional rate by which tracer leaves plasma and is being trapped in an organ. Commonly it is obtained from the slope of a Patlak plot, where it is the increase in tissue activity concentration normalized by plasma activity concentration that occurs in a unit of normalized time." [NCI Thesaurus:https\://ncit.nci.nih.gov/ncitbrowser/pages/message.jsf] +def: "A fractional rate by which tracer leaves plasma and is being trapped in an organ. Commonly it is obtained from the slope of a Patlak plot, where it is the increase in tissue activity concentration normalized by plasma activity concentration that occurs in a unit of normalized time." [https://ncit.nci.nih.gov/ncitbrowser/] synonym: "Influx Constant" RELATED [] synonym: "Kin,brain" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement @@ -28557,7 +28557,7 @@ creation_date: 2019-05-22T15:12:32Z [Term] id: CMO:0003172 name: verapamil apparent influx permeability clearance in retina barrier -def: "A fractional rate by which tracer leaves plasma and is being trapped in an organ. Commonly it is obtained from the slope of a Patlak plot, where it is the increase in tissue activity concentration normalized by plasma activity concentration that occurs in a unit of normalized time." [NCI Thesaurus:https\://ncit.nci.nih.gov/ncitbrowser/] +def: "A fractional rate by which tracer leaves plasma and is being trapped in an organ. Commonly it is obtained from the slope of a Patlak plot, where it is the increase in tissue activity concentration normalized by plasma activity concentration that occurs in a unit of normalized time." [https://ncit.nci.nih.gov/ncitbrowser/] synonym: "retina Verapamil influx constant, Kin,retina" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement created_by: sjwang @@ -28566,7 +28566,7 @@ creation_date: 2019-05-22T15:18:50Z [Term] id: CMO:0003173 name: verapamil apparent influx permeability clearance in aqueous humor -def: "A fractional rate by which tracer leaves plasma and is being trapped in an organ. Commonly it is obtained from the slope of a Patlak plot, where it is the increase in tissue activity concentration normalized by plasma activity concentration that occurs in a unit of normalized time." [NCI Thesaurus:https\://ncit.nci.nih.gov/ncitbrowser/pages/message.jsf] +def: "A fractional rate by which tracer leaves plasma and is being trapped in an organ. Commonly it is obtained from the slope of a Patlak plot, where it is the increase in tissue activity concentration normalized by plasma activity concentration that occurs in a unit of normalized time." [https://ncit.nci.nih.gov/ncitbrowser/pages/message.jsf] synonym: "Kin,aqueoushumor" RELATED [] synonym: "Verapamil influx constant" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement @@ -28576,7 +28576,7 @@ creation_date: 2019-05-22T15:23:45Z [Term] id: CMO:0003174 name: verapamil equilibrated distribution volume in brain -def: "The apparent volume occupied by an exogenous compound during the time point when the plasma concentration of the compound reaches steady state levels in the brain" [NCI Thesaurus:https\://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&version=19.04f&ns=ncit&code=C85538&key=1864625640&b=1&n=null] +def: "The apparent volume occupied by an exogenous compound during the time point when the plasma concentration of the compound reaches steady state levels in the brain" [https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&version=19.04f&ns=ncit&code=C85538&key=1864625640&b=1&n=null] synonym: "Steady State Volume of Distribution" EXACT [] synonym: "Vt" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement @@ -28586,7 +28586,7 @@ creation_date: 2019-05-22T15:46:03Z [Term] id: CMO:0003175 name: verapamil equilibrated distribution volume in retina -def: "The apparent volume occupied by an exogenous compound during the time point when the plasma concentration of the compound reaches steady state levels in the retina." [NCI Thesaurus:https\://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&version=19.04f&ns=ncit&code=C85538&key=1864625640&b=1&n=null] +def: "The apparent volume occupied by an exogenous compound during the time point when the plasma concentration of the compound reaches steady state levels in the retina." [https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&version=19.04f&ns=ncit&code=C85538&key=1864625640&b=1&n=null] synonym: "Steady State Volume of Distribution" EXACT [] synonym: "Vt" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement @@ -28596,7 +28596,7 @@ creation_date: 2019-05-22T15:50:17Z [Term] id: CMO:0003176 name: verapamil equilibrated distribution volume in aqueous humor -def: "The apparent volume occupied by an exogenous compound during the time point when the plasma concentration of the compound reaches steady state levels in the aqueous humor." [NCI Thesaurus:https\://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&version=19.04f&ns=ncit&code=C85538&key=1864625640&b=1&n=null] +def: "The apparent volume occupied by an exogenous compound during the time point when the plasma concentration of the compound reaches steady state levels in the aqueous humor." [https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&version=19.04f&ns=ncit&code=C85538&key=1864625640&b=1&n=null] synonym: "Steady State Volume of Distribution" EXACT [] synonym: "Vt" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement @@ -28606,7 +28606,7 @@ creation_date: 2019-05-22T15:52:42Z [Term] id: CMO:0003177 name: verapamil uptake index in brain -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the brain. Measured by scintillation counter." [PMID:PMID\: 21638281\,PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the brain. Measured by scintillation counter." [PMID:21638281,PMID:7315440] synonym: "BUI of verapamil" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement created_by: sjwang @@ -28615,7 +28615,7 @@ creation_date: 2019-05-22T16:10:22Z [Term] id: CMO:0003178 name: verapamil uptake index in retina -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the retina. Measured by scintillation counter." [PMID:PMID\: 21638281\,PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the retina. Measured by scintillation counter." [PMID:21638281, PMID:7315440] synonym: "RUI of verapamil" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement created_by: sjwang @@ -28624,7 +28624,7 @@ creation_date: 2019-05-22T16:13:27Z [Term] id: CMO:0003179 name: verapamil uptake index in aqueous humor -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the aqueous humor. Measured by scintillation counter" [PMID:PMID\: 21638281\, PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the aqueous humor. Measured by scintillation counter" [PMID::21638281, PMID:7315440] synonym: "AHUI of verapamil" RELATED [] is_a: CMO:0003171 ! blood verapami metabolism measurement created_by: sjwang @@ -28647,7 +28647,7 @@ creation_date: 2019-05-22T16:28:15Z [Term] id: CMO:0003182 name: digoxin uptake index in aqueous humor -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the aqueous humor. Measured by scintillation counter" [PMID:PMID\: 21638281\, PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the aqueous humor. Measured by scintillation counter" [PMID:21638281, PMID:7315440] synonym: "AHUI of digoxin" RELATED [] is_a: CMO:0003180 ! blood digoxin metabolism measurement created_by: sjwang @@ -28656,7 +28656,7 @@ creation_date: 2019-05-22T16:30:55Z [Term] id: CMO:0003183 name: digoxin uptake index in brain -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the brain. Measured by scintillation counter." [PMID:PMID\: 21638281\, PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the brain. Measured by scintillation counter." [PMID:21638281, PMID:7315440] synonym: "BUI of digoxin" RELATED [] is_a: CMO:0003180 ! blood digoxin metabolism measurement created_by: sjwang @@ -28665,7 +28665,7 @@ creation_date: 2019-05-22T16:32:46Z [Term] id: CMO:0003184 name: digoxin uptake index in retina -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the retina. Measured by scintillation counter." [PMID:PMID\: 21638281\, PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the retina. Measured by scintillation counter." [PMID:21638281, PMID:7315440] synonym: "RUI of digoxin" RELATED [] is_a: CMO:0003180 ! blood digoxin metabolism measurement created_by: sjwang @@ -28674,7 +28674,7 @@ creation_date: 2019-05-22T16:34:06Z [Term] id: CMO:0003185 name: quinidine uptake index in aqueous humor -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the aqueous humor. Measured by scintillation counter" [PMID:PMID\: 21638281\, PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the aqueous humor. Measured by scintillation counter" [PMID:21638281, PMID:7315440] synonym: "AHUI of quinidine" RELATED [] is_a: CMO:0003181 ! blood quinidine metabolism measurement created_by: sjwang @@ -28683,7 +28683,7 @@ creation_date: 2019-05-22T16:35:38Z [Term] id: CMO:0003186 name: quinidine uptake index in brain -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the brain. Measured by scintillation counter." [PMID:PMID\: 21638281\, PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the brain. Measured by scintillation counter." [PMID:21638281, PMID:7315440] synonym: "BUI of quinidine" RELATED [] is_a: CMO:0003181 ! blood quinidine metabolism measurement created_by: sjwang @@ -28692,7 +28692,7 @@ creation_date: 2019-05-22T16:36:38Z [Term] id: CMO:0003187 name: quinidine uptake index in retina -def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the retina. Measured by scintillation counter." [PMID:PMID\: 21638281\, PMID\: 7315440] +def: "Percentage of radiolabeled substance to radiolabeled vehicle in injected solution compared to radiolabeled substance to radiolabeled vehicle measured in the retina. Measured by scintillation counter." [PMID:21638281, PMID:7315440] synonym: "RUI of quinidine" RELATED [] is_a: CMO:0003181 ! blood quinidine metabolism measurement created_by: sjwang @@ -28782,7 +28782,7 @@ creation_date: 2019-07-17T09:56:11Z [Term] id: CMO:0003198 name: blood reactive oxygen metabolite level -def: "Reactive oxygen metabolites are hydroperoxides measured as derivatives in a DROM spectrophotometric test." [PMID:PMID\:25630910] +def: "Reactive oxygen metabolites are hydroperoxides measured as derivatives in a DROM spectrophotometric test." [PMID:25630910] is_a: CMO:0000023 ! blood chemistry measurement created_by: sjwang creation_date: 2019-07-17T09:57:40Z @@ -28790,7 +28790,7 @@ creation_date: 2019-07-17T09:57:40Z [Term] id: CMO:0003199 name: serum reactive oxygen metabolite level -def: "Reactive oxygen metabolites are hydroperoxides measured as derivatives in a DROM spectrophotometric test." [PMID:PMID\:25630910] +def: "Reactive oxygen metabolites are hydroperoxides measured as derivatives in a DROM spectrophotometric test." [PMID:25630910] is_a: CMO:0003198 ! blood reactive oxygen metabolite level created_by: sjwang creation_date: 2019-07-17T10:00:13Z @@ -28798,7 +28798,7 @@ creation_date: 2019-07-17T10:00:13Z [Term] id: CMO:0003200 name: left ventricle end-diastolic wall stress -def: "Left ventricle end-diastolic wall stress (LVED-WS) is calculated measurement of the force acting against the left ventricle wall at the endo of diastole, that is when the heart muscle is maximally relaxed, and usually corresponds to its largest diameter. It is calculated by multiplying ventricular pressure by ventricular radius and dividing by 2 times the wall thickness. Commonly referred to as Law of Laplace (PMID: 2198115)" [PMID:PMID\:2198115] +def: "Left ventricle end-diastolic wall stress (LVED-WS) is calculated measurement of the force acting against the left ventricle wall at the endo of diastole, that is when the heart muscle is maximally relaxed, and usually corresponds to its largest diameter. It is calculated by multiplying ventricular pressure by ventricular radius and dividing by 2 times the wall thickness. Commonly referred to as Law of Laplace (PMID: 2198115)" [PMID:2198115] synonym: "LVED-WS" RELATED [] is_a: CMO:0002992 ! calculated left ventricular end-diastolic blood pressure measurement created_by: sjwang @@ -28807,7 +28807,7 @@ creation_date: 2019-07-22T15:26:26Z [Term] id: CMO:0003201 name: Left ventricle end-systolic wall stress -def: "Left ventricle end-systolic wall stress (LVES-WS)is calculated measurement of the force acting against the left ventricle wall at the endo of end of systole, the period of contraction of the heart when the blood is forced from the ventricles into the pulmonary artery (right ventricle) and the aorta (left ventricle). It is calculated by multiplying ventricular pressure by ventricular radius and dividing by 2 times the wall thickness. Commonly referred to as Law of Laplace (PMID: 2198115)" [PMID:PMID\: 2198115] +def: "Left ventricle end-systolic wall stress (LVES-WS)is calculated measurement of the force acting against the left ventricle wall at the endo of end of systole, the period of contraction of the heart when the blood is forced from the ventricles into the pulmonary artery (right ventricle) and the aorta (left ventricle). It is calculated by multiplying ventricular pressure by ventricular radius and dividing by 2 times the wall thickness. Commonly referred to as Law of Laplace (PMID: 2198115)" [PMID:2198115] synonym: "LVES-WS" RELATED [] is_a: CMO:0002884 ! calculated left ventricular end-systolic blood pressure created_by: sjwang @@ -28816,7 +28816,7 @@ creation_date: 2019-07-22T15:33:47Z [Term] id: CMO:0003202 name: Myocardial interstitial angiotensin II level -def: "Angiotensin II collected by microdialysis probe with semipermeable membrane fiber at a depth of 4 mm within the LV myocardium free wall." [PMID:PMID\: 22768235] +def: "Angiotensin II collected by microdialysis probe with semipermeable membrane fiber at a depth of 4 mm within the LV myocardium free wall." [PMID:22768235] is_a: CMO:0002863 ! heart molecular composition measurement created_by: sjwang creation_date: 2019-07-22T15:48:05Z @@ -28824,7 +28824,7 @@ creation_date: 2019-07-22T15:48:05Z [Term] id: CMO:0003203 name: Myocardial interstitial bradykinin -def: "Bradykinin collected by microdialysis probe with semipermeable membrane fiber at a depth of 4 mm within the LV myocardium free wall - PMID: 22768235" [PMID:PMID\: 22768235] +def: "Bradykinin collected by microdialysis probe with semipermeable membrane fiber at a depth of 4 mm within the LV myocardium free wall - PMID: 22768235" [PMID:22768235] is_a: CMO:0002863 ! heart molecular composition measurement created_by: sjwang creation_date: 2019-07-22T15:57:30Z @@ -28832,7 +28832,7 @@ creation_date: 2019-07-22T15:57:30Z [Term] id: CMO:0003204 name: Myocardial interstitial norepinephrine -def: "Norepinephrine collected by microdialysis probe with semipermeable membrane fiber at a depth of 4 mm within the LV myocardium free wall - PMID: 22768235" [PMID:PMID\: 22768235] +def: "Norepinephrine collected by microdialysis probe with semipermeable membrane fiber at a depth of 4 mm within the LV myocardium free wall - PMID: 22768235" [PMID:22768235] is_a: CMO:0002863 ! heart molecular composition measurement created_by: sjwang creation_date: 2019-07-22T15:59:52Z @@ -28840,7 +28840,7 @@ creation_date: 2019-07-22T15:59:52Z [Term] id: CMO:0003205 name: Myocardial interstitial epinephrine -def: "Epinephrine collected by microdialysis probe with semipermeable membrane fiber at a depth of 4 mm within the LV myocardium free wall - PMID: 22768235" [PMID:PMID\: 22768235] +def: "Epinephrine collected by microdialysis probe with semipermeable membrane fiber at a depth of 4 mm within the LV myocardium free wall - PMID: 22768235" [PMID:22768235] is_a: CMO:0002863 ! heart molecular composition measurement created_by: sjwang creation_date: 2019-07-22T16:01:55Z @@ -28866,7 +28866,7 @@ creation_date: 2019-07-22T16:17:38Z [Term] id: CMO:0003208 name: glucose disappearance constant -def: "The rate constant associated with glucose disappearance from a loaded system." [PMID:PMID\:13367210] +def: "The rate constant associated with glucose disappearance from a loaded system." [PMID:13367210] synonym: "Kitt" RELATED [] synonym: "rate constant for glucose utilization" RELATED [] is_a: CMO:0000352 ! calculated blood glucose level @@ -28876,7 +28876,7 @@ creation_date: 2019-07-24T13:54:54Z [Term] id: CMO:0003209 name: heart left ventricle weight to right ventricle weight ratio -def: "A calculated value which compares the weight of the left ventricle, the lower chamber of the left side of the heart, which pumps oxygenated blood out through the aorta to all the tissues of the body, with the weight of the right ventricle, the lower chamber of the right side of the heart, which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung, and presents it as a ratio." [DRUGBANK:https\://www.drugbank.ca/drugs/DB00421] +def: "A calculated value which compares the weight of the left ventricle, the lower chamber of the left side of the heart, which pumps oxygenated blood out through the aorta to all the tissues of the body, with the weight of the right ventricle, the lower chamber of the right side of the heart, which pumps venous blood through the pulmonary trunk and arteries to the capillaries of the lung, and presents it as a ratio." [https://www.drugbank.ca/drugs/DB00421] is_obsolete: true created_by: sjwang creation_date: 2019-07-24T14:40:19Z @@ -28893,7 +28893,7 @@ creation_date: 2019-07-24T14:40:47Z [Term] id: CMO:0003211 name: Homeostatic Model Assessment of Beta cell function -def: "Homeostatic model assessment (HOMA-Beta) is a method for assessing β-cell function from basal (fasting) glucose and insulin or C-peptide concentrations. The empirical formulae: HOMA-Beta = 20 x fasting insulin (uU/mL) /[fasting glycemia (mmol=L)- 3.5]" [PMID:PMID\:24182515] +def: "Homeostatic model assessment (HOMA-Beta) is a method for assessing β-cell function from basal (fasting) glucose and insulin or C-peptide concentrations. The empirical formulae: HOMA-Beta = 20 x fasting insulin (uU/mL) /[fasting glycemia (mmol=L)- 3.5]" [PMID:24182515] synonym: "HOMA-b" EXACT [] is_a: CMO:0000352 ! calculated blood glucose level is_a: CMO:0000353 ! calculated blood insulin level @@ -28903,7 +28903,7 @@ creation_date: 2019-07-24T15:13:53Z [Term] id: CMO:0003212 name: Adrenal angiotensin II type 1 receptor density -def: "A measurement of the amount of angiotensin II type 1 receptor, the angiotensin receptor exhibiting vasopressor effects, regulation of aldosterone secretion and blood pressure and volume control, in a specified sample of adrenal tissue expressed relative to the weight of total protein in that sample." [wikipedia:https\://en.wikipedia.org/wiki/Angiotensin_II_receptor_type_1] +def: "A measurement of the amount of angiotensin II type 1 receptor, the angiotensin receptor exhibiting vasopressor effects, regulation of aldosterone secretion and blood pressure and volume control, in a specified sample of adrenal tissue expressed relative to the weight of total protein in that sample." [https://en.wikipedia.org/wiki/Angiotensin_II_receptor_type_1] is_a: CMO:0002988 ! adrenal protein/peptide composition measurement created_by: sjwang creation_date: 2019-07-24T15:43:04Z @@ -29068,7 +29068,7 @@ creation_date: 2019-08-01T11:48:30Z [Term] id: CMO:0003232 name: red blood cell distribution width- standard deviation (RDW-SD) -def: "RDW-SD is a measurement derived from the red blood cell distribution curves generated on automated hematology analyzers and is an indicator of variation in RBC size within a blood sample. The RDW is used along with the indices (MCV, MCH, MCHC) to describe a population of RBCs. The RDW measures the deviation of the RBC width, not the actual width or size of individual cells. The RDW-SD is an actual measurement of the width of the red cell distribution curve in femtoliters (fL). The width of the distribution curve is measured at the point that is 20% above the baseline. Since the RDW-SD is an actual measurement, it is not influenced by the MCV and more accurately reflects the red cell size variance." [LabCE:https\://www.labce.com/spg579122_red_blood_cell_distribution_width_rdw_definition_a.aspx] +def: "RDW-SD is a measurement derived from the red blood cell distribution curves generated on automated hematology analyzers and is an indicator of variation in RBC size within a blood sample. The RDW is used along with the indices (MCV, MCH, MCHC) to describe a population of RBCs. The RDW measures the deviation of the RBC width, not the actual width or size of individual cells. The RDW-SD is an actual measurement of the width of the red cell distribution curve in femtoliters (fL). The width of the distribution curve is measured at the point that is 20% above the baseline. Since the RDW-SD is an actual measurement, it is not influenced by the MCV and more accurately reflects the red cell size variance." [https://www.labce.com/spg579122_red_blood_cell_distribution_width_rdw_definition_a.aspx] is_a: CMO:0003102 ! red blood cell morphological measurement created_by: sjwang creation_date: 2019-08-01T15:34:18Z