diff --git a/Cargo.lock b/Cargo.lock
index 0c8ccc8..72ccfb4 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -511,7 +511,7 @@ dependencies = [
  "autocfg",
  "cfg-if",
  "crossbeam-utils",
- "memoffset",
+ "memoffset 0.8.0",
  "scopeguard",
 ]
 
@@ -1039,6 +1039,15 @@ dependencies = [
  "autocfg",
 ]
 
+[[package]]
+name = "memoffset"
+version = "0.9.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "5a634b1c61a95585bd15607c6ab0c4e5b226e695ff2800ba0cdccddf208c406c"
+dependencies = [
+ "autocfg",
+]
+
 [[package]]
 name = "minimal-lexical"
 version = "0.2.1"
@@ -1458,14 +1467,14 @@ dependencies = [
 
 [[package]]
 name = "pyo3"
-version = "0.18.3"
+version = "0.19.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e3b1ac5b3731ba34fdaa9785f8d74d17448cd18f30cf19e0c7e7b1fdb5272109"
+checksum = "ffb88ae05f306b4bfcde40ac4a51dc0b05936a9207a4b75b798c7729c4258a59"
 dependencies = [
  "cfg-if",
  "indoc",
  "libc",
- "memoffset",
+ "memoffset 0.9.0",
  "parking_lot 0.12.1",
  "pyo3-build-config",
  "pyo3-ffi",
@@ -1475,9 +1484,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-build-config"
-version = "0.18.3"
+version = "0.19.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "9cb946f5ac61bb61a5014924910d936ebd2b23b705f7a4a3c40b05c720b079a3"
+checksum = "554db24f0b3c180a9c0b1268f91287ab3f17c162e15b54caaae5a6b3773396b0"
 dependencies = [
  "once_cell",
  "target-lexicon",
@@ -1485,9 +1494,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-ffi"
-version = "0.18.3"
+version = "0.19.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "fd4d7c5337821916ea2a1d21d1092e8443cf34879e53a0ac653fbb98f44ff65c"
+checksum = "922ede8759e8600ad4da3195ae41259654b9c55da4f7eec84a0ccc7d067a70a4"
 dependencies = [
  "libc",
  "pyo3-build-config",
@@ -1495,9 +1504,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-macros"
-version = "0.18.3"
+version = "0.19.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "a9d39c55dab3fc5a4b25bbd1ac10a2da452c4aca13bb450f22818a002e29648d"
+checksum = "8a5caec6a1dd355964a841fcbeeb1b89fe4146c87295573f94228911af3cc5a2"
 dependencies = [
  "proc-macro2",
  "pyo3-macros-backend",
@@ -1507,9 +1516,9 @@ dependencies = [
 
 [[package]]
 name = "pyo3-macros-backend"
-version = "0.18.3"
+version = "0.19.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "97daff08a4c48320587b5224cc98d609e3c27b6d437315bd40b605c98eeb5918"
+checksum = "e0b78ccbb160db1556cdb6fd96c50334c5d4ec44dc5e0a968d0a1208fa0efa8b"
 dependencies = [
  "proc-macro2",
  "quote",
diff --git a/Cargo.toml b/Cargo.toml
index 3088f7f..dd41a03 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -38,7 +38,7 @@ parity-scale-codec = { version = "3.2.1", optional = true, features = ["max-enco
 postgres-types = { version = "0.2.3", optional = true }
 primitive-types = { version = "<1", optional = true }
 proptest = { version = "1.0", optional = true }
-pyo3 = { version = "0.18.3", optional = true }
+pyo3 = { version = "0.19.1", optional = true }
 quickcheck = { version = "1.0", optional = true }
 rand = { version = "0.8.5", optional = true }
 rlp = { version = "0.5.1", optional = true }