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web pages of database #177

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HMU-lyz opened this issue Sep 23, 2024 · 2 comments
Open

web pages of database #177

HMU-lyz opened this issue Sep 23, 2024 · 2 comments

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@HMU-lyz
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HMU-lyz commented Sep 23, 2024

Database integration is a feature of liana. Has the author considered making the database interactive with web pages to make it easier to query the database?

@deeenes
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deeenes commented Sep 25, 2024

Hi,

Liana uses our prior knowledge handling tool OmniPath to access most of its databases. Then Liana uses its own custom client side processing utilities to tailor it according to its needs. Also in R, but especially in the Python side, we plan to move some of these processing functionalities into more database oriented packages, such as OmniPath and NetworkCommons, to make them more broadly available and easier to use. This includes adding new features to OmniPath itself. We probably don't plan with interactive web page for Liana, but we do for OmniPath, especially in OmnipathR and NetworkCommons (heavily under development). We expect to do these only in second half of next year. Something I really curious about, how do you imagine such a web page, what would you use if for, what kind of information would you like to see? It would be a helpful input to hear about this from you.

Best,
Denes

@HMU-lyz
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HMU-lyz commented Sep 26, 2024

Hi,

Liana uses our prior knowledge handling tool OmniPath to access most of its databases. Then Liana uses its own custom client side processing utilities to tailor it according to its needs. Also in R, but especially in the Python side, we plan to move some of these processing functionalities into more database oriented packages, such as OmniPath and NetworkCommons, to make them more broadly available and easier to use. This includes adding new features to OmniPath itself. We probably don't plan with interactive web page for Liana, but we do for OmniPath, especially in OmnipathR and NetworkCommons (heavily under development). We expect to do these only in second half of next year. Something I really curious about, how do you imagine such a web page, what would you use if for, what kind of information would you like to see? It would be a helpful input to hear about this from you.

Best, Denes

Hi Denes,
I want to know what are the specific functions of some of the ligand receptors when I use the liana package for cell interaction prediction. Or like the cellchat algorithm, the ligand receptor interaction is assigned to the pathway. Because I am more concerned about the biological functions that these ligand receptors may play in diseases, to better explain the causes of disease development. In general, I hope to get these annotation information when I query a ligand receptor on the interaction page.

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