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Issues with processing indels in VCF #40

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shadrinams opened this issue Mar 5, 2021 · 1 comment
Open

Issues with processing indels in VCF #40

shadrinams opened this issue Mar 5, 2021 · 1 comment

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@shadrinams
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shadrinams commented Mar 5, 2021

Hello,
I am using VCF files (created by Mutect) as input for haplogrep2 and I am having issues with processing indels, which are longer than 1-bp.

I had to change "285 GAA -> G" to two variants: "286 A -> * " and "287 A -> * " and only then haplogrep recognized the deletion.
I still cannot make it to pass insertions. I tried to replace "1760 G->GT" to "1761 * -> T" but haplogrep complains about "​ * ".
When I use "1760 G->GT", haplogrep2 recognize it as "1760G".

Is it expected behavior and how can I fix it?
Thank you!

@seppinho
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Hi,
Sorry for the late response. Can you provide an example so I can fix that.

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