diff --git a/.github/workflows/nightly-tests.yaml b/.github/workflows/nightly-tests.yaml
index 8034d4d1d2f..4400fd448c5 100644
--- a/.github/workflows/nightly-tests.yaml
+++ b/.github/workflows/nightly-tests.yaml
@@ -56,7 +56,7 @@ jobs:
     name: End-to-End (branch=${{ github.ref_name }}, cluster=${{ matrix.test.cluster-name }}, version=${{ matrix.version-files.label }} )
     if: ${{ github.event_name == 'workflow_dispatch' && inputs.run-kubernetes-end-to-end && inputs.branch == 'workflow_initiating_branch' }}
     runs-on: ubuntu-22.04
-    timeout-minutes: 150
+    timeout-minutes: 180
     strategy:
       # Since we are running these on a schedule, there is no value in failing fast
       # In fact, we want to ensure that all tests run, so that we have a clearer picture of which tests are prone to flaking
@@ -66,7 +66,7 @@ jobs:
           # When running the tests at night, there is no value in splitting the tests across multiple clusters and running them in parallel.
           # As a result, we increase the threshold for the tests, since they all run serially on a single cluster
           - cluster-name: 'cluster-one'
-            go-test-args: '-v -timeout=120m'
+            go-test-args: '-v -timeout=150m'
             go-test-run-regex: ${{ inputs.kubernetes-end-to-end-run-regex }}
         # In our nightly tests, we run the suite of tests using the lower and upper ends of versions that we claim to support
         # The versions should mirror: https://docs.solo.io/gloo-edge/latest/reference/support/
@@ -117,7 +117,7 @@ jobs:
     name: End-to-End (branch=main, cluster=${{ matrix.test.cluster-name }}, version=${{ matrix.version-files.label }} )
     if: ${{ (github.event_name == 'workflow_dispatch' && inputs.run-kubernetes-end-to-end && inputs.branch == 'main') || github.event.schedule == '0 5 * * *' }}
     runs-on: ubuntu-22.04
-    timeout-minutes: 150
+    timeout-minutes: 180
     strategy:
       # Since we are running these on a schedule, there is no value in failing fast
       # In fact, we want to ensure that all tests run, so that we have a clearer picture of which tests are prone to flaking
@@ -127,7 +127,7 @@ jobs:
           # When running the tests at night, there is no value in splitting the tests across multiple clusters and running them in parallel.
           # As a result, we increase the threshold for the tests, since they all run serially on a single cluster
           - cluster-name: 'cluster-one'
-            go-test-args: '-v -timeout=120m'
+            go-test-args: '-v -timeout=150m'
             # Specifying an empty regex means all tests will be run.
             go-test-run-regex: ""
         # In our nightly tests, we run the suite of tests using the lower and upper ends of versions that we claim to support
@@ -174,6 +174,7 @@ jobs:
           istio-version: ${{ steps.dotenv.outputs.istio_version }}
           matrix-label: ${{ matrix.version-files.label }}
 
+  # Reminder: when setting up the job next release branch, copy from "end_to_end_tests_main" not the previous release job as configuration may have changed
   end_to_end_tests_17:
     name: End-to-End (branch=v1.17.x, cluster=${{ matrix.test.cluster-name }}, version=${{ matrix.version-files.label }} )
     if: ${{ (github.event_name == 'workflow_dispatch' && inputs.run-kubernetes-end-to-end && inputs.branch == 'v1.17.x') || github.event.schedule == '0 6 * * 1' }}
diff --git a/changelog/v1.18.0-rc2/e2e-timeout-bump.yaml b/changelog/v1.18.0-rc2/e2e-timeout-bump.yaml
new file mode 100644
index 00000000000..6270fe73786
--- /dev/null
+++ b/changelog/v1.18.0-rc2/e2e-timeout-bump.yaml
@@ -0,0 +1,6 @@
+changelog:
+  - type: FIX
+    issueLink: https://github.com/solo-io/gloo/issues/10380
+    resolvesIssue: true
+    description: >-
+      Bump the timeout for the nightly e2e tests