diff --git a/spyder_kernels/console/tests/test_console_kernel.py b/spyder_kernels/console/tests/test_console_kernel.py
index 06349c0d..ceda7c3f 100644
--- a/spyder_kernels/console/tests/test_console_kernel.py
+++ b/spyder_kernels/console/tests/test_console_kernel.py
@@ -1406,5 +1406,35 @@ def test_django_settings(kernel):
     assert "'settings':" in nsview
 
 
+@flaky(max_runs=3)
+def test_running_namespace_profile(tmpdir):
+    """
+    Test that profile can get variables from running namespace.
+    """
+    # Command to start the kernel
+    cmd = "from spyder_kernels.console import start; start.main()"
+
+    with setup_kernel(cmd) as client:
+        # Remove all variables
+        client.execute_interactive("%reset -f", timeout=TIMEOUT)
+
+        # Write defined variable code to a file
+        code = "result = 10\n%profile print(result)\nsucess=True"
+        d = tmpdir.join("defined-test.ipy")
+        d.write(code)
+
+        # Run code file `d`
+        client.execute_interactive("%runfile {}"
+                                  .format(repr(str(d))), timeout=TIMEOUT)
+
+        # Verify that `result` is defined in the current namespace
+        client.inspect('sucess')
+        msg = client.get_shell_msg(timeout=TIMEOUT)
+        while "found" not in msg['content']:
+            msg = client.get_shell_msg(timeout=TIMEOUT)
+        content = msg['content']
+        assert content['found']
+
+
 if __name__ == "__main__":
     pytest.main()
diff --git a/spyder_kernels/customize/code_runner.py b/spyder_kernels/customize/code_runner.py
index e3eb2a4a..911e7e12 100644
--- a/spyder_kernels/customize/code_runner.py
+++ b/spyder_kernels/customize/code_runner.py
@@ -197,6 +197,29 @@ def debugfile(self, line, local_ns=None):
                 context_locals=local_ns,
             )
 
+    @runfile_arguments
+    @needs_local_scope
+    @line_magic
+    def profilefile(self, line, local_ns=None):
+        """
+        Profile a file.
+        """
+        args, local_ns = self._parse_runfile_argstring(
+            self.profilefile, line, local_ns)
+
+        with self._profile_exec() as prof_exec:
+            self._exec_file(
+                filename=args.filename,
+                canonic_filename=args.canonic_filename,
+                wdir=args.wdir,
+                current_namespace=args.current_namespace,
+                args=args.args,
+                exec_fun=prof_exec,
+                post_mortem=args.post_mortem,
+                context_globals=args.namespace,
+                context_locals=local_ns,
+            )
+
     @runcell_arguments
     @needs_local_scope
     @line_magic
@@ -235,6 +258,36 @@ def debugcell(self, line, local_ns=None):
                 context_locals=local_ns,
             )
 
+    @runcell_arguments
+    @needs_local_scope
+    @line_magic
+    def profilecell(self, line, local_ns=None):
+        """
+        Profile a code cell from an editor.
+        """
+        args = self._parse_runcell_argstring(self.profilecell, line)
+
+        with self._profile_exec() as prof_exec:
+            return self._exec_cell(
+                cell_id=args.cell_id,
+                filename=args.filename,
+                canonic_filename=args.canonic_filename,
+                exec_fun=prof_exec,
+                post_mortem=args.post_mortem,
+                context_globals=self.shell.user_ns,
+                context_locals=local_ns,
+            )
+
+    @no_var_expand
+    @needs_local_scope
+    @line_cell_magic
+    def profile(self, line, cell=None, local_ns=None):
+        """Profile the given line."""
+        if cell is not None:
+            line += "\n" + cell
+        with self._profile_exec() as prof_exec:
+            return prof_exec(line, self.shell.user_ns, local_ns)
+
     @contextmanager
     def _debugger_exec(self, filename, continue_if_has_breakpoints):
         """Get an exec function to use for debugging."""
@@ -274,6 +327,41 @@ def debug_exec(code, glob, loc):
             # debugger (self) is not aware of this.
             session._previous_step = None
 
+    @contextmanager
+    def _profile_exec(self):
+        """Get an exec function for profiling."""
+        with tempfile.TemporaryDirectory() as tempdir:
+            # Reset the tracing function in case we are debugging
+            trace_fun = sys.gettrace()
+            sys.settrace(None)
+            # Get a file to save the results
+            profile_filename = os.path.join(tempdir, "profile.prof")
+            try:
+                if self.shell.is_debugging():
+                    def prof_exec(code, glob, loc):
+                        # if we are debugging (tracing), call_tracing is
+                        # necessary for profiling
+                        return sys.call_tracing(cProfile.runctx, (
+                            code, glob, loc, profile_filename
+                        ))
+                    yield prof_exec
+                else:
+                    yield partial(cProfile.runctx, filename=profile_filename)
+            finally:
+                # Resect tracing function
+                sys.settrace(trace_fun)
+                if os.path.isfile(profile_filename):
+                    # Send result to frontend
+                    with open(profile_filename, "br") as f:
+                        profile_result = f.read()
+                    try:
+                        frontend_request(blocking=False).show_profile_file(
+                            profile_result, create_pathlist()
+                        )
+                    except CommError:
+                        logger.debug(
+                            "Could not send profile result to the frontend.")
+
     def _exec_file(
         self,
         filename=None,