You need home brew. Then...
brew install libusb
sudo easy_install pyusb
Use python to run the script:
python ./cgminerLCDStats.py --host MINERIP
That is it.
If you want it to start when you login create a file in ~/Library/LaunchAgents/com.foobar.plist:
<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE plist PUBLIC "-//Apple//DTD PLIST 1.0//EN" "http://www.apple.com/DTDs/PropertyList-1.0.dtd">
<plist version="1.0">
<dict>
<key>Label</key>
<string>com.spencer.minermon</string>
<key>ProgramArguments</key>
<array>
<string>python</string>
<string>/Users/username/rcs/cgminerLCDStats/cgminerLCDStats.py</string>
<string>--host</string>
<string>MINERIP</string>
<string>--mtgoxDisplayOff</string>
</array>
<key>StandardOutPath</key>
<string>/dev/null</string>
<key>StandardErrorPath</key>
<string>/dev/null</string>
<key>KeepAlive</key>
<true/>
</dict>
</plist>
Start it manually to test:
launchctl load ~/Library/LaunchAgents/com.foobar.plist