udm_6_0_0_reaction_classes.xsd

<?xml version="1.0" encoding="utf-8"?>
<!--

    Pistoia Alliance UDM XML Schema.

    Copyright (c) Pistoia Alliance, 2018-2020.

    Licensor hereby grants you the right, without charge, on a perpetual,
    non-exclusive and worldwide basis, to utilize this UDM XML Schema
    Definition (and the UDM File Format based on it) for the purpose of
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    modify the format or create derivative works of the Definition that are
    not compatible with the UDM File Format, except that licensee may provide
    additional requirements for content included in the SECTION element
    provided that such requirements still validate against the UDM XML schema.
    For the avoidance of doubt, products implementing this Definition are not
    deemed to be derivative works of the UDM XML Schema Definition.

-->
<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema"
           elementFormDefault="qualified"
           attributeFormDefault="unqualified"
           version="6.0.0">

  <!--
      The countries, methods, reaction classes, result types and units UDM
      vocabularies are defined in as separate files to minimise changes in the
      main UDM XML schema file between version 5.x and 6.x.

      Reaction classes are based on the RXNO reaction ontology (version from 9
      February 2020): https://github.com/rsc-ontologies/rxno
  -->

  <xs:simpleType name="reactionClass">
    <xs:restriction base="xs:string">
      <!--
          MOP - the molecular process ontology.
      -->
      <xs:enumeration value="formylation" /> <!-- MOP:0000003 -->
      <xs:enumeration value="silylation" /> <!-- MOP:0000339 -->
      <xs:enumeration value="methylation" /> <!-- MOP:0000364 -->
      <xs:enumeration value="alkylation" /> <!-- MOP:0000369 -->
      <xs:enumeration value="hydrocarbylation" /> <!-- MOP:0000410 -->
      <xs:enumeration value="arylation" /> <!-- MOP:0000411 -->
      <xs:enumeration value="allylation" /> <!-- MOP:0000422 -->
      <xs:enumeration value="organylation" /> <!-- MOP:0000458 -->
      <xs:enumeration value="acylation" /> <!-- MOP:0000479 -->
      <xs:enumeration value="sulfonylation" /> <!-- MOP:0000539 -->
      <xs:enumeration value="molecular process" /> <!-- MOP:0000543 -->
      <xs:enumeration value="halogenation" /> <!-- MOP:0000550 -->
      <xs:enumeration value="imination" /> <!-- MOP:0000555 -->
      <xs:enumeration value="nitration" /> <!-- MOP:0000556 -->
      <xs:enumeration value="cyclization" /> <!-- MOP:0000561 -->
      <xs:enumeration value="cycloaddition" /> <!-- MOP:0000562 -->
      <xs:enumeration value="[2+2] cycloaddition" /> <!-- MOP:0000563 -->
      <xs:enumeration value="cycloelimination" /> <!-- MOP:0000564 -->
      <xs:enumeration value="[4+2] cycloaddition" /> <!-- MOP:0000565 -->
      <xs:enumeration value="formation of covalent bond with group" /> <!-- MOP:0000566 -->
      <xs:enumeration value="breaking of covalent bond with group" /> <!-- MOP:0000567 -->
      <xs:enumeration value="oxidation" /> <!-- MOP:0000568 -->
      <xs:enumeration value="reduction" /> <!-- MOP:0000569 -->
      <xs:enumeration value="electron attachment" /> <!-- MOP:0000570 -->
      <xs:enumeration value="aldehyde reduction" /> <!-- MOP:0000571 -->
      <xs:enumeration value="alcohol oxidation" /> <!-- MOP:0000572 -->
      <xs:enumeration value="primary alcohol oxidation to aldehyde" /> <!-- MOP:0000573 -->
      <xs:enumeration value="secondary alcohol oxidation to ketone" /> <!-- MOP:0000574 -->
      <xs:enumeration value="amine oxidation" /> <!-- MOP:0000575 -->
      <xs:enumeration value="imine reduction" /> <!-- MOP:0000576 -->
      <xs:enumeration value="ester reduction" /> <!-- MOP:0000577 -->
      <xs:enumeration value="ester reduction to aldehyde" /> <!-- MOP:0000578 -->
      <xs:enumeration value="ester reduction to primary alcohol" /> <!-- MOP:0000579 -->
      <xs:enumeration value="ketone reduction" /> <!-- MOP:0000580 -->
      <xs:enumeration value="alkene oxidation" /> <!-- MOP:0000581 -->
      <xs:enumeration value="alkene oxidation to 1,2-diol" /> <!-- MOP:0000582 -->
      <xs:enumeration value="alkene ozonolysis" /> <!-- MOP:0000583 -->
      <xs:enumeration value="primary alkene oxidation to carboxylic acid and carbon dioxide" /> <!-- MOP:0000584 -->
      <xs:enumeration value="tertiary alkene oxidation to carboxylic acid and ketone" /> <!-- MOP:0000585 -->
      <xs:enumeration value="secondary, non-terminal alkene oxidation to aldehydes" /> <!-- MOP:0000586 -->
      <xs:enumeration value="secondary terminal alkene oxidation to ketone and carbon dioxide" /> <!-- MOP:0000587 -->
      <xs:enumeration value="quaternary alkene oxidation to ketones" /> <!-- MOP:0000588 -->
      <xs:enumeration value="hydrogenation" /> <!-- MOP:0000589 -->
      <xs:enumeration value="pseudohalogenation" /> <!-- MOP:0000596 -->
      <xs:enumeration value="condensation reaction" /> <!-- MOP:0000627 -->
      <xs:enumeration value="molecular dehydration reaction" /> <!-- MOP:0000628 -->
      <xs:enumeration value="amination" /> <!-- MOP:0000650 -->
      <xs:enumeration value="elimination reaction" /> <!-- MOP:0000656 -->
      <xs:enumeration value="epoxidation" /> <!-- MOP:0000671 -->
      <xs:enumeration value="oxidation at sulfur" /> <!-- MOP:0000705 -->
      <xs:enumeration value="oxidation at nitrogen" /> <!-- MOP:0000706 -->
      <xs:enumeration value="oxidation state" /> <!-- MOP:0000712 -->
      <xs:enumeration value="carboxylation" /> <!-- MOP:0000713 -->
      <xs:enumeration value="carbonyl oxidation to alkyne" /> <!-- MOP:0000714 -->
      <xs:enumeration value="[3+2] cycloaddition" /> <!-- MOP:0000715 -->
      <xs:enumeration value="enolisation" /> <!-- MOP:0000716 -->
      <xs:enumeration value="enolisability" /> <!-- MOP:0000717 -->
      <xs:enumeration value="enolisable carbonyl compound" /> <!-- MOP:0000718 -->
      <xs:enumeration value="O-dealkylation" /> <!-- MOP:0000719 -->
      <xs:enumeration value="[2+2+1] cycloaddition" /> <!-- MOP:0000720 -->
      <xs:enumeration value="[3,3]-sigmatropic rearrangement" /> <!-- MOP:0000721 -->
      <xs:enumeration value="decarboxylative condensation" /> <!-- MOP:0000722 -->
      <xs:enumeration value="deethanolative condensation" /> <!-- MOP:0000723 -->
      <xs:enumeration value="Brønsted acid catalysis" /> <!-- MOP:0000730 -->
      <xs:enumeration value="base catalysis" /> <!-- MOP:0000731 -->
      <xs:enumeration value="hydron donation" /> <!-- MOP:0000732 -->
      <xs:enumeration value="accepting an electron pair in Lewis adduct formation" /> <!-- MOP:0000733 -->
      <xs:enumeration value="Lewis acid catalysis" /> <!-- MOP:0000734 -->
      <xs:enumeration value="Lewis base catalysis" /> <!-- MOP:0000735 -->
      <xs:enumeration value="Brønsted base catalysis" /> <!-- MOP:0000736 -->
      <xs:enumeration value="accepting a hydron" /> <!-- MOP:0000737 -->
      <xs:enumeration value="electron pair donation in Lewis adduct formation" /> <!-- MOP:0000738 -->
      <xs:enumeration value="Lewis adduct formation" /> <!-- MOP:0000739 -->
      <xs:enumeration value="acid catalysis" /> <!-- MOP:0000740 -->
      <xs:enumeration value="substitution reaction" /> <!-- MOP:0000790 -->
      <xs:enumeration value="aromatic substitution" /> <!-- MOP:0000791 -->
      <xs:enumeration value="allylic rearrangement" /> <!-- MOP:0000792 -->
      <xs:enumeration value="N-substitution" /> <!-- MOP:0000793 -->
      <xs:enumeration value="O-substitution" /> <!-- MOP:0000794 -->
      <xs:enumeration value="S-substitution" /> <!-- MOP:0000795 -->
      <xs:enumeration value="formation of covalent bond with nitrogen centre" /> <!-- MOP:0000802 -->
      <xs:enumeration value="dealkylation" /> <!-- MOP:0001369 -->
      <xs:enumeration value="deorganylation" /> <!-- MOP:0001458 -->
      <xs:enumeration value="dehalogenation" /> <!-- MOP:0001550 -->
      <xs:enumeration value="decarboxylation" /> <!-- MOP:0001713 -->
      <xs:enumeration value="N-methylation" /> <!-- MOP:0002364 -->
      <xs:enumeration value="N-alkylation" /> <!-- MOP:0002369 -->
      <xs:enumeration value="N-arylation" /> <!-- MOP:0002411 -->
      <xs:enumeration value="N-acylation" /> <!-- MOP:0002479 -->
      <xs:enumeration value="N-sulfonylation" /> <!-- MOP:0002524 -->
      <xs:enumeration value="O-silylation" /> <!-- MOP:0003339 -->
      <xs:enumeration value="O-acylation" /> <!-- MOP:0003479 -->
      <xs:enumeration value="O-sulfonylation" /> <!-- MOP:0003524 -->
      <xs:enumeration value="P-alkylation" /> <!-- MOP:0006369 -->
      <xs:enumeration value="solvolysis" /> <!-- MOP:0000618 -->
      <xs:enumeration value="hydrolysis" /> <!-- MOP:0000619 -->
      <xs:enumeration value="dealcoholative condensation" /> <!-- MOP:0000825 -->
      <xs:enumeration value="dienophilicity" /> <!-- MOP:0000826 -->
      <!--
          RXNO - the name reaction ontology.
      -->
      <xs:enumeration value="molecular skeleton joining reaction" /> <!-- RXNO:0000000 -->
      <xs:enumeration value="planned reaction step" /> <!-- RXNO:0000001 -->
      <xs:enumeration value="carbon-carbon coupling reaction" /> <!-- RXNO:0000002 -->
      <xs:enumeration value="Perkin reaction" /> <!-- RXNO:0000003 -->
      <xs:enumeration value="obsolete: ring reaction" /> <!-- RXNO:0000004 -->
      <xs:enumeration value="ring formation reaction step" /> <!-- RXNO:0000005 -->
      <xs:enumeration value="Diels-Alder reaction" /> <!-- RXNO:0000006 -->
      <xs:enumeration value="ene reaction" /> <!-- RXNO:0000007 -->
      <xs:enumeration value="conjugate addition" /> <!-- RXNO:0000008 -->
      <xs:enumeration value="Michael addition" /> <!-- RXNO:0000009 -->
      <xs:enumeration value="functional modification" /> <!-- RXNO:0000010 -->
      <xs:enumeration value="functional group modification" /> <!-- RXNO:0000011 -->
      <xs:enumeration value="functional group oxidation" /> <!-- RXNO:0000012 -->
      <xs:enumeration value="diazotisation" /> <!-- RXNO:0000013 -->
      <xs:enumeration value="Grignard reaction" /> <!-- RXNO:0000014 -->
      <xs:enumeration value="Wittig reaction" /> <!-- RXNO:0000015 -->
      <xs:enumeration value="aldol addition" /> <!-- RXNO:0000016 -->
      <xs:enumeration value="aldol condensation" /> <!-- RXNO:0000017 -->
      <xs:enumeration value="1,3-dipolar cycloaddition" /> <!-- RXNO:0000018 -->
      <xs:enumeration value="Sandmeyer reaction" /> <!-- RXNO:0000021 -->
      <xs:enumeration value="Gattermann halogenation" /> <!-- RXNO:0000022 -->
      <xs:enumeration value="Koerner-Contardi reaction" /> <!-- RXNO:0000023 -->
      <xs:enumeration value="Heck reaction" /> <!-- RXNO:0000024 -->
      <xs:enumeration value="rearrangement step" /> <!-- RXNO:0000025 -->
      <xs:enumeration value="Beckmann rearrangement" /> <!-- RXNO:0000026 -->
      <xs:enumeration value="Cope rearrangement" /> <!-- RXNO:0000028 -->
      <xs:enumeration value="oxy-Cope rearrangement" /> <!-- RXNO:0000029 -->
      <xs:enumeration value="molecular skeleton insertion reaction" /> <!-- RXNO:0000030 -->
      <xs:enumeration value="Baeyer-Villiger oxidation" /> <!-- RXNO:0000031 -->
      <xs:enumeration value="Mannich reaction" /> <!-- RXNO:0000032 -->
      <xs:enumeration value="Mitsunobu reaction" /> <!-- RXNO:0000034 -->
      <xs:enumeration value="Stille coupling" /> <!-- RXNO:0000035 -->
      <xs:enumeration value="Reformatsky reaction" /> <!-- RXNO:0000036 -->
      <xs:enumeration value="functional group reduction" /> <!-- RXNO:0000037 -->
      <xs:enumeration value="Clemmensen reduction" /> <!-- RXNO:0000038 -->
      <xs:enumeration value="carbon-carbon homocoupling reaction" /> <!-- RXNO:0000039 -->
      <xs:enumeration value="Ullmann reaction" /> <!-- RXNO:0000040 -->
      <xs:enumeration value="addition reaction step" /> <!-- RXNO:0000041 -->
      <xs:enumeration value="Birch reduction" /> <!-- RXNO:0000042 -->
      <xs:enumeration value="Claisen condensation" /> <!-- RXNO:0000043 -->
      <xs:enumeration value="Knoevenagel condensation" /> <!-- RXNO:0000044 -->
      <xs:enumeration value="Friedel-Crafts acylation" /> <!-- RXNO:0000045 -->
      <xs:enumeration value="Friedel-Crafts alkylation" /> <!-- RXNO:0000046 -->
      <xs:enumeration value="Oppenauer oxidation" /> <!-- RXNO:0000047 -->
      <xs:enumeration value="Prins reaction" /> <!-- RXNO:0000048 -->
      <xs:enumeration value="intramolecular Prins reaction" /> <!-- RXNO:0000049 -->
      <xs:enumeration value="pinacol rearrangement" /> <!-- RXNO:0000050 -->
      <xs:enumeration value="Wolff rearrangement" /> <!-- RXNO:0000051 -->
      <xs:enumeration value="fused-ring-system formation" /> <!-- RXNO:0000052 -->
      <xs:enumeration value="Bischler-Napieralski reaction" /> <!-- RXNO:0000053 -->
      <xs:enumeration value="Curtius rearrangement" /> <!-- RXNO:0000054 -->
      <xs:enumeration value="Vilsmeier-Haack reaction" /> <!-- RXNO:0000055 -->
      <xs:enumeration value="Horner-Wadsworth-Emmons reaction" /> <!-- RXNO:0000056 -->
      <xs:enumeration value="Horner reaction" /> <!-- RXNO:0000057 -->
      <xs:enumeration value="Ritter reaction" /> <!-- RXNO:0000058 -->
      <xs:enumeration value="Pictet-Spengler reaction" /> <!-- RXNO:0000059 -->
      <xs:enumeration value="Arbuzov reaction" /> <!-- RXNO:0000060 -->
      <xs:enumeration value="Mukaiyama aldol condensation" /> <!-- RXNO:0000061 -->
      <xs:enumeration value="Skraup reaction" /> <!-- RXNO:0000062 -->
      <xs:enumeration value="Arndt-Eistert reaction" /> <!-- RXNO:0000063 -->
      <xs:enumeration value="Fischer indole synthesis" /> <!-- RXNO:0000064 -->
      <xs:enumeration value="Dieckmann cyclisation" /> <!-- RXNO:0000065 -->
      <xs:enumeration value="Staudinger reaction" /> <!-- RXNO:0000066 -->
      <xs:enumeration value="benzidine rearrangement" /> <!-- RXNO:0000067 -->
      <xs:enumeration value="semidine rearrangement" /> <!-- RXNO:0000068 -->
      <xs:enumeration value="Dimroth rearrangement" /> <!-- RXNO:0000069 -->
      <xs:enumeration value="chain lengthening" /> <!-- RXNO:0000070 -->
      <xs:enumeration value="Edman degradation" /> <!-- RXNO:0000071 -->
      <xs:enumeration value="Reimer-Tiemann reaction" /> <!-- RXNO:0000072 -->
      <xs:enumeration value="cleaving reaction" /> <!-- RXNO:0000073 -->
      <xs:enumeration value="Wurtz reaction" /> <!-- RXNO:0000074 -->
      <xs:enumeration value="benzilic acid rearrangement" /> <!-- RXNO:0000075 -->
      <xs:enumeration value="Baylis-Hillman reaction" /> <!-- RXNO:0000076 -->
      <xs:enumeration value="Darzens reaction" /> <!-- RXNO:0000077 -->
      <xs:enumeration value="protection reaction" /> <!-- RXNO:0000078 -->
      <xs:enumeration value="Boc protection" /> <!-- RXNO:0000079 -->
      <xs:enumeration value="Peterson olefination" /> <!-- RXNO:0000080 -->
      <xs:enumeration value="Ullmann condensation" /> <!-- RXNO:0000081 -->
      <xs:enumeration value="Goldberg reaction" /> <!-- RXNO:0000082 -->
      <xs:enumeration value="Paternò–Büchi reaction" /> <!-- RXNO:0000083 -->
      <xs:enumeration value="Barbier reaction" /> <!-- RXNO:0000084 -->
      <xs:enumeration value="acyloin condensation" /> <!-- RXNO:0000085 -->
      <xs:enumeration value="Henry reaction" /> <!-- RXNO:0000086 -->
      <xs:enumeration value="Barton reaction" /> <!-- RXNO:0000087 -->
      <xs:enumeration value="Negishi coupling" /> <!-- RXNO:0000088 -->
      <xs:enumeration value="Meerwein-Ponndorf-Verley reduction" /> <!-- RXNO:0000089 -->
      <xs:enumeration value="Williamson ether synthesis" /> <!-- RXNO:0000090 -->
      <xs:enumeration value="Wittig methylenation" /> <!-- RXNO:0000091 -->
      <xs:enumeration value="aza-Diels-Alder reaction" /> <!-- RXNO:0000092 -->
      <xs:enumeration value="extrusion reaction" /> <!-- RXNO:0000093 -->
      <xs:enumeration value="Ramberg-Backlund reaction" /> <!-- RXNO:0000094 -->
      <xs:enumeration value="Fischer-Hepp rearrangement" /> <!-- RXNO:0000095 -->
      <xs:enumeration value="azo coupling" /> <!-- RXNO:0000096 -->
      <xs:enumeration value="imino-Reformatsky reaction" /> <!-- RXNO:0000097 -->
      <xs:enumeration value="Glaser coupling" /> <!-- RXNO:0000098 -->
      <xs:enumeration value="Eglinton reaction" /> <!-- RXNO:0000099 -->
      <xs:enumeration value="Cadiot-Chodkiewicz coupling" /> <!-- RXNO:0000100 -->
      <xs:enumeration value="Leuckart reaction" /> <!-- RXNO:0000101 -->
      <xs:enumeration value="Leuckart-Wallach reaction" /> <!-- RXNO:0000102 -->
      <xs:enumeration value="Gabriel synthesis" /> <!-- RXNO:0000103 -->
      <xs:enumeration value="Ing-Manske procedure" /> <!-- RXNO:0000104 -->
      <xs:enumeration value="end-of-chain chain shortening" /> <!-- RXNO:0000105 -->
      <xs:enumeration value="Hunsdiecker reaction" /> <!-- RXNO:0000106 -->
      <xs:enumeration value="malonic ester synthesis" /> <!-- RXNO:0000107 -->
      <xs:enumeration value="ring expansion" /> <!-- RXNO:0000108 -->
      <xs:enumeration value="Pfitzinger reaction" /> <!-- RXNO:0000109 -->
      <xs:enumeration value="fragmentation reaction" /> <!-- RXNO:0000110 -->
      <xs:enumeration value="Grob fragmentation" /> <!-- RXNO:0000111 -->
      <xs:enumeration value="Brook rearrangement" /> <!-- RXNO:0000113 -->
      <xs:enumeration value="Nicholas reaction" /> <!-- RXNO:0000114 -->
      <xs:enumeration value="Nicholas reaction, nucleophilic heteroatom centre" /> <!-- RXNO:0000115 -->
      <xs:enumeration value="Nicholas reaction, nucleophilic carbon centre" /> <!-- RXNO:0000116 -->
      <xs:enumeration value="Julia olefination" /> <!-- RXNO:0000117 -->
      <xs:enumeration value="Sommelet reaction" /> <!-- RXNO:0000118 -->
      <xs:enumeration value="Bouveault-Blanc reaction" /> <!-- RXNO:0000119 -->
      <xs:enumeration value="Payne rearrangement" /> <!-- RXNO:0000120 -->
      <xs:enumeration value="aza-Payne rearrangement" /> <!-- RXNO:0000121 -->
      <xs:enumeration value="Baker-Venkataraman rearrangement" /> <!-- RXNO:0000122 -->
      <xs:enumeration value="molecular skeleton elimination reaction" /> <!-- RXNO:0000123 -->
      <xs:enumeration value="Bamford-Stevens reaction" /> <!-- RXNO:0000124 -->
      <xs:enumeration value="Shapiro reaction" /> <!-- RXNO:0000125 -->
      <xs:enumeration value="Doebner reaction" /> <!-- RXNO:0000126 -->
      <xs:enumeration value="Balz-Schiemann reaction" /> <!-- RXNO:0000127 -->
      <xs:enumeration value="Kolbe electrolysis" /> <!-- RXNO:0000128 -->
      <xs:enumeration value="Ugi reaction" /> <!-- RXNO:0000129 -->
      <xs:enumeration value="Wacker-Tsuji oxidation" /> <!-- RXNO:0000130 -->
      <xs:enumeration value="Wacker process" /> <!-- RXNO:0000131 -->
      <xs:enumeration value="Monsanto process" /> <!-- RXNO:0000132 -->
      <xs:enumeration value="Cativa process" /> <!-- RXNO:0000133 -->
      <xs:enumeration value="Barton-McCombie deoxygenation" /> <!-- RXNO:0000134 -->
      <xs:enumeration value="Barton decarboxylation" /> <!-- RXNO:0000135 -->
      <xs:enumeration value="Rosenmund reduction" /> <!-- RXNO:0000136 -->
      <xs:enumeration value="Sonogashira coupling" /> <!-- RXNO:0000137 -->
      <xs:enumeration value="benzoin condensation" /> <!-- RXNO:0000138 -->
      <xs:enumeration value="Gattermann reaction" /> <!-- RXNO:0000139 -->
      <xs:enumeration value="Suzuki-Miyaura coupling" /> <!-- RXNO:0000140 -->
      <xs:enumeration value="Sharpless asymmetric epoxidation" /> <!-- RXNO:0000141 -->
      <xs:enumeration value="Sharpless asymmetric dihydroxylation" /> <!-- RXNO:0000142 -->
      <xs:enumeration value="Sharpless asymmetric aminohydroxylation" /> <!-- RXNO:0000143 -->
      <xs:enumeration value="Kumada coupling" /> <!-- RXNO:0000144 -->
      <xs:enumeration value="Barbier-Wieland degradation" /> <!-- RXNO:0000145 -->
      <xs:enumeration value="Corey-Fuchs reaction" /> <!-- RXNO:0000146 -->
      <xs:enumeration value="Emde degradation" /> <!-- RXNO:0000147 -->
      <xs:enumeration value="Claisen rearrangement" /> <!-- RXNO:0000148 -->
      <xs:enumeration value="Ireland-Claisen rearrangement" /> <!-- RXNO:0000149 -->
      <xs:enumeration value="joining with rearrangement" /> <!-- RXNO:0000150 -->
      <xs:enumeration value="Bellus-Claisen rearrangement" /> <!-- RXNO:0000151 -->
      <xs:enumeration value="Eschenmoser-Claisen rearrangement" /> <!-- RXNO:0000152 -->
      <xs:enumeration value="Johnson-Claisen rearrangement" /> <!-- RXNO:0000153 -->
      <xs:enumeration value="Swern oxidation" /> <!-- RXNO:0000154 -->
      <xs:enumeration value="Finkelstein reaction" /> <!-- RXNO:0000155 -->
      <xs:enumeration value="Lossen rearrangement" /> <!-- RXNO:0000156 -->
      <xs:enumeration value="Nef reaction" /> <!-- RXNO:0000157 -->
      <xs:enumeration value="Japp-Klingemann reaction" /> <!-- RXNO:0000158 -->
      <xs:enumeration value="Doebner-Miller reaction" /> <!-- RXNO:0000159 -->
      <xs:enumeration value="Fmoc protection" /> <!-- RXNO:0000160 -->
      <xs:enumeration value="Paal-Knorr synthesis" /> <!-- RXNO:0000161 -->
      <xs:enumeration value="Paal-Knorr furan synthesis" /> <!-- RXNO:0000162 -->
      <xs:enumeration value="Paal-Knorr thiophene synthesis" /> <!-- RXNO:0000163 -->
      <xs:enumeration value="Paal-Knorr pyrrole synthesis" /> <!-- RXNO:0000164 -->
      <xs:enumeration value="Schotten-Baumann reaction" /> <!-- RXNO:0000165 -->
      <xs:enumeration value="Hofmann elimination" /> <!-- RXNO:0000166 -->
      <xs:enumeration value="Fischer-Speier esterification" /> <!-- RXNO:0000167 -->
      <xs:enumeration value="Weerman reaction" /> <!-- RXNO:0000168 -->
      <xs:enumeration value="Dakin reaction" /> <!-- RXNO:0000169 -->
      <xs:enumeration value="Schmidt rearrangement, carboxylic acid" /> <!-- RXNO:0000170 -->
      <xs:enumeration value="Schmidt rearrangement, ketone" /> <!-- RXNO:0000171 -->
      <xs:enumeration value="Schmidt rearrangement, tertiary alcohol" /> <!-- RXNO:0000172 -->
      <xs:enumeration value="Schmidt rearrangement, alkene" /> <!-- RXNO:0000173 -->
      <xs:enumeration value="Sommelet-Hauser rearrangement" /> <!-- RXNO:0000174 -->
      <xs:enumeration value="Dakin-West reaction" /> <!-- RXNO:0000175 -->
      <xs:enumeration value="Beckmann fragmentation" /> <!-- RXNO:0000176 -->
      <xs:enumeration value="Kharasch reaction" /> <!-- RXNO:0000177 -->
      <xs:enumeration value="Kharasch-Sosnovsky reaction" /> <!-- RXNO:0000178 -->
      <xs:enumeration value="Elbs persulfate oxidation, phenol variant" /> <!-- RXNO:0000179 -->
      <xs:enumeration value="Elbs persulfate oxidation, tolyl variant" /> <!-- RXNO:0000180 -->
      <xs:enumeration value="Boyland-Sims oxidation" /> <!-- RXNO:0000181 -->
      <xs:enumeration value="Kolbe-Schmitt reaction" /> <!-- RXNO:0000182 -->
      <xs:enumeration value="Perkow reaction" /> <!-- RXNO:0000183 -->
      <xs:enumeration value="Pfitzner-Moffatt oxidation" /> <!-- RXNO:0000184 -->
      <xs:enumeration value="Willgerodt reaction" /> <!-- RXNO:0000185 -->
      <xs:enumeration value="Willgerodt-Kindler reaction" /> <!-- RXNO:0000186 -->
      <xs:enumeration value="Tishchenko reaction" /> <!-- RXNO:0000187 -->
      <xs:enumeration value="Zimmermann reaction" /> <!-- RXNO:0000188 -->
      <xs:enumeration value="Neber rearrangement" /> <!-- RXNO:0000189 -->
      <xs:enumeration value="Nozaki-Hiyama-Kishi reaction" /> <!-- RXNO:0000191 -->
      <xs:enumeration value="Buchwald-Hartwig amination" /> <!-- RXNO:0000192 -->
      <xs:enumeration value="Hiyama coupling" /> <!-- RXNO:0000193 -->
      <xs:enumeration value="Stevens rearrangement" /> <!-- RXNO:0000194 -->
      <xs:enumeration value="Stevens rearrangement, ammonium" /> <!-- RXNO:0000195 -->
      <xs:enumeration value="Stevens rearrangement, sulfonium" /> <!-- RXNO:0000196 -->
      <xs:enumeration value="aza-Cope rearrangement" /> <!-- RXNO:0000197 -->
      <xs:enumeration value="2-aza-Cope rearrangement" /> <!-- RXNO:0000198 -->
      <xs:enumeration value="3-aza-Cope rearrangement" /> <!-- RXNO:0000199 -->
      <xs:enumeration value="1-aza-Cope rearrangement" /> <!-- RXNO:0000200 -->
      <xs:enumeration value="Steglich rearrangement" /> <!-- RXNO:0000201 -->
      <xs:enumeration value="ring rearrangement" /> <!-- RXNO:0000202 -->
      <xs:enumeration value="deprotection reaction" /> <!-- RXNO:0000203 -->
      <xs:enumeration value="multiple-bond metathesis" /> <!-- RXNO:0000204 -->
      <xs:enumeration value="ring breaking" /> <!-- RXNO:0000205 -->
      <xs:enumeration value="ring contraction" /> <!-- RXNO:0000206 -->
      <xs:enumeration value="Strecker reaction" /> <!-- RXNO:0000207 -->
      <xs:enumeration value="aromatic Claisen rearrangement" /> <!-- RXNO:0000208 -->
      <xs:enumeration value="Nazarov cyclisation" /> <!-- RXNO:0000209 -->
      <xs:enumeration value="Fleming-Tamao oxidation" /> <!-- RXNO:0000210 -->
      <xs:enumeration value="Tamao oxidation" /> <!-- RXNO:0000211 -->
      <xs:enumeration value="Sakurai reaction, aldehyde or ketone" /> <!-- RXNO:0000212 -->
      <xs:enumeration value="Sakurai reaction, enone" /> <!-- RXNO:0000213 -->
      <xs:enumeration value="Sakurai reaction, acid chloride" /> <!-- RXNO:0000214 -->
      <xs:enumeration value="Sakurai reaction, acetal or ketal" /> <!-- RXNO:0000215 -->
      <xs:enumeration value="imine Sakurai reaction" /> <!-- RXNO:0000216 -->
      <xs:enumeration value="Sakurai reaction, epoxide" /> <!-- RXNO:0000217 -->
      <xs:enumeration value="Cannizzaro reaction" /> <!-- RXNO:0000218 -->
      <xs:enumeration value="crossed Cannizzaro reaction" /> <!-- RXNO:0000219 -->
      <xs:enumeration value="Pummerer rearrangement" /> <!-- RXNO:0000220 -->
      <xs:enumeration value="Polonovski reaction" /> <!-- RXNO:0000221 -->
      <xs:enumeration value="Polonovski-Potier reaction" /> <!-- RXNO:0000222 -->
      <xs:enumeration value="Menshutkin reaction" /> <!-- RXNO:0000223 -->
      <xs:enumeration value="Strecker degradation" /> <!-- RXNO:0000224 -->
      <xs:enumeration value="Wohl-Ziegler bromination" /> <!-- RXNO:0000225 -->
      <xs:enumeration value="Wolff-Kishner reduction" /> <!-- RXNO:0000226 -->
      <xs:enumeration value="Wolff-Kishner reduction, Huang-Minlon modification" /> <!-- RXNO:0000227 -->
      <xs:enumeration value="Zemplen transesterification" /> <!-- RXNO:0000228 -->
      <xs:enumeration value="Ferrier rearrangement" /> <!-- RXNO:0000229 -->
      <xs:enumeration value="aza-Ferrier rearrangement" /> <!-- RXNO:0000230 -->
      <xs:enumeration value="aza-ene reaction" /> <!-- RXNO:0000231 -->
      <xs:enumeration value="Petasis reaction" /> <!-- RXNO:0000232 -->
      <xs:enumeration value="Achmatowicz rearrangement" /> <!-- RXNO:0000233 -->
      <xs:enumeration value="aza-Achmatowicz rearrangement" /> <!-- RXNO:0000234 -->
      <xs:enumeration value="aza-Henry reaction" /> <!-- RXNO:0000235 -->
      <xs:enumeration value="Biginelli reaction" /> <!-- RXNO:0000236 -->
      <xs:enumeration value="Blaise reaction" /> <!-- RXNO:0000237 -->
      <xs:enumeration value="Katritzky pyrylium-pyridinium method" /> <!-- RXNO:0000238 -->
      <xs:enumeration value="metalla-aza-Claisen rearrangement" /> <!-- RXNO:0000239 -->
      <xs:enumeration value="Bergman cyclisation" /> <!-- RXNO:0000240 -->
      <xs:enumeration value="nitro-Michael reaction" /> <!-- RXNO:0000241 -->
      <xs:enumeration value="Noyori asymmetric hydrogenation, alkene" /> <!-- RXNO:0000242 -->
      <xs:enumeration value="Noyori asymmetric hydrogenation, carbonyl" /> <!-- RXNO:0000243 -->
      <xs:enumeration value="Passerini reaction" /> <!-- RXNO:0000244 -->
      <xs:enumeration value="ring-closing metathesis" /> <!-- RXNO:0000245 -->
      <xs:enumeration value="polymerisation reaction" /> <!-- RXNO:0000246 -->
      <xs:enumeration value="ring-opening metathesis polymerisation" /> <!-- RXNO:0000247 -->
      <xs:enumeration value="Carroll rearrangement" /> <!-- RXNO:0000248 -->
      <xs:enumeration value="Bose-Mitsunobu reaction" /> <!-- RXNO:0000249 -->
      <xs:enumeration value="Fritsch-Buttenberg-Wiechell rearrangement" /> <!-- RXNO:0000250 -->
      <xs:enumeration value="Stork-Wittig olefination" /> <!-- RXNO:0000251 -->
      <xs:enumeration value="Cadogan carbazole synthesis" /> <!-- RXNO:0000252 -->
      <xs:enumeration value="Cadogan coupling" /> <!-- RXNO:0000253 -->
      <xs:enumeration value="MacDonald condensation" /> <!-- RXNO:0000254 -->
      <xs:enumeration value="Zweifel diene synthesis" /> <!-- RXNO:0000255 -->
      <xs:enumeration value="Dess-Martin oxidation" /> <!-- RXNO:0000256 -->
      <xs:enumeration value="Criegee oxidation" /> <!-- RXNO:0000257 -->
      <xs:enumeration value="Simmons-Smith reaction" /> <!-- RXNO:0000258 -->
      <xs:enumeration value="Wittig rearrangement" /> <!-- RXNO:0000259 -->
      <xs:enumeration value="[1,2]-Wittig rearrangement" /> <!-- RXNO:0000260 -->
      <xs:enumeration value="[2,3]-Wittig rearrangement" /> <!-- RXNO:0000261 -->
      <xs:enumeration value="[1,2]-aza-Wittig rearrangement" /> <!-- RXNO:0000262 -->
      <xs:enumeration value="[2,3]-aza-Wittig rearrangement" /> <!-- RXNO:0000263 -->
      <xs:enumeration value="aza-Baylis-Hillman reaction" /> <!-- RXNO:0000264 -->
      <xs:enumeration value="aza-Wittig reaction" /> <!-- RXNO:0000265 -->
      <xs:enumeration value="Fenton reaction" /> <!-- RXNO:0000266 -->
      <xs:enumeration value="Hantzsch pyridine synthesis" /> <!-- RXNO:0000268 -->
      <xs:enumeration value="alkyne-azide click reaction" /> <!-- RXNO:0000269 -->
      <xs:enumeration value="copper(I)-catalyzed azide-alkyne cycloaddition" /> <!-- RXNO:0000270 -->
      <xs:enumeration value="Fischer-Tropsch process" /> <!-- RXNO:0000271 -->
      <xs:enumeration value="hydroformylation" /> <!-- RXNO:0000272 -->
      <xs:enumeration value="retro-Diels-Alder reaction" /> <!-- RXNO:0000273 -->
      <xs:enumeration value="retro-aldol addition" /> <!-- RXNO:0000274 -->
      <xs:enumeration value="Stork-Crabtree hydrogenation" /> <!-- RXNO:0000275 -->
      <xs:enumeration value="Aufbau reaction" /> <!-- RXNO:0000276 -->
      <xs:enumeration value="hydroalumination" /> <!-- RXNO:0000277 -->
      <xs:enumeration value="hydrovinylation" /> <!-- RXNO:0000278 -->
      <xs:enumeration value="1,4-hydrovinylation" /> <!-- RXNO:0000279 -->
      <xs:enumeration value="alkene metathesis" /> <!-- RXNO:0000280 -->
      <xs:enumeration value="alkyne metathesis" /> <!-- RXNO:0000281 -->
      <xs:enumeration value="enyne metathesis" /> <!-- RXNO:0000282 -->
      <xs:enumeration value="ring-closing enyne metathesis" /> <!-- RXNO:0000283 -->
      <xs:enumeration value="ring-opening metathesis" /> <!-- RXNO:0000284 -->
      <xs:enumeration value="Luche reaction" /> <!-- RXNO:0000285 -->
      <xs:enumeration value="Luche reduction" /> <!-- RXNO:0000286 -->
      <xs:enumeration value="Lindgren oxidation" /> <!-- RXNO:0000287 -->
      <xs:enumeration value="Rosenmund-von Braun reaction" /> <!-- RXNO:0000288 -->
      <xs:enumeration value="Woehler reaction" /> <!-- RXNO:0000289 -->
      <xs:enumeration value="hydrosilylation" /> <!-- RXNO:0000290 -->
      <xs:enumeration value="hydroamination" /> <!-- RXNO:0000291 -->
      <xs:enumeration value="hydroboration" /> <!-- RXNO:0000292 -->
      <xs:enumeration value="hydroboration-oxidation" /> <!-- RXNO:0000293 -->
      <xs:enumeration value="hydrometallation" /> <!-- RXNO:0000294 -->
      <xs:enumeration value="hydrozirconation" /> <!-- RXNO:0000295 -->
      <xs:enumeration value="hydrostannylation" /> <!-- RXNO:0000296 -->
      <xs:enumeration value="hydrotelluration" /> <!-- RXNO:0000297 -->
      <xs:enumeration value="Fetizon oxidation" /> <!-- RXNO:0000298 -->
      <xs:enumeration value="Vorbrueggen condensation" /> <!-- RXNO:0000299 -->
      <xs:enumeration value="thiol-ene reaction" /> <!-- RXNO:0000300 -->
      <xs:enumeration value="Yamamoto polymerisation" /> <!-- RXNO:0000301 -->
      <xs:enumeration value="thermal hydrosilylation" /> <!-- RXNO:0000302 -->
      <xs:enumeration value="photohydrosilylation" /> <!-- RXNO:0000303 -->
      <xs:enumeration value="Julia-Kocienski olefination" /> <!-- RXNO:0000304 -->
      <xs:enumeration value="seleno-Pummerer rearrangement" /> <!-- RXNO:0000305 -->
      <xs:enumeration value="intramolecular Heck reaction" /> <!-- RXNO:0000306 -->
      <xs:enumeration value="Mori-Ban indole synthesis" /> <!-- RXNO:0000307 -->
      <xs:enumeration value="Yamaguchi lactonisation" /> <!-- RXNO:0000308 -->
      <xs:enumeration value="Yamaguchi esterification" /> <!-- RXNO:0000309 -->
      <xs:enumeration value="oxa-Diels-Alder reaction" /> <!-- RXNO:0000310 -->
      <xs:enumeration value="Tsuji-Trost reaction" /> <!-- RXNO:0000311 -->
      <xs:enumeration value="Clauson-Kaas reaction" /> <!-- RXNO:0000312 -->
      <xs:enumeration value="hetero-Diels-Alder reaction" /> <!-- RXNO:0000313 -->
      <xs:enumeration value="palladium-catalysed carbon-carbon coupling reaction" /> <!-- RXNO:0000316 -->
      <xs:enumeration value="ester condensation reaction" /> <!-- RXNO:0000317 -->
      <xs:enumeration value="amino group deprotection" /> <!-- RXNO:0000320 -->
      <xs:enumeration value="amino group protection" /> <!-- RXNO:0000321 -->
      <xs:enumeration value="benzylamine protection" /> <!-- RXNO:0000322 -->
      <xs:enumeration value="hydroxyl group protection" /> <!-- RXNO:0000323 -->
      <xs:enumeration value="benzyl ether protection" /> <!-- RXNO:0000324 -->
      <xs:enumeration value="carboxylic acid protection" /> <!-- RXNO:0000325 -->
      <xs:enumeration value="Boc deprotection" /> <!-- RXNO:0000326 -->
      <xs:enumeration value="benzylamine deprotection" /> <!-- RXNO:0000327 -->
      <xs:enumeration value="silyl protection" /> <!-- RXNO:0000328 -->
      <xs:enumeration value="planned synthesis" /> <!-- RXNO:0000329 -->
      <xs:enumeration value="acetate protection" /> <!-- RXNO:0000330 -->
      <xs:enumeration value="substitution step" /> <!-- RXNO:0000331 -->
      <xs:enumeration value="aromatic substitution step" /> <!-- RXNO:0000332 -->
      <xs:enumeration value="Sandmeyer halogenation" /> <!-- RXNO:0000333 -->
      <xs:enumeration value="Sandmeyer pseudohalogenation" /> <!-- RXNO:0000334 -->
      <xs:enumeration value="reductive amination" /> <!-- RXNO:0000335 -->
      <xs:enumeration value="nitro reduction to amine" /> <!-- RXNO:0000337 -->
      <xs:enumeration value="amide reduction to amine" /> <!-- RXNO:0000338 -->
      <xs:enumeration value="alkene reduction to alkane" /> <!-- RXNO:0000339 -->
      <xs:enumeration value="amide N-alkylation" /> <!-- RXNO:0000340 -->
      <xs:enumeration value="aniline N-alkylation" /> <!-- RXNO:0000341 -->
      <xs:enumeration value="nitrile reduction to amine" /> <!-- RXNO:0000342 -->
      <xs:enumeration value="imine reduction to amine" /> <!-- RXNO:0000343 -->
      <xs:enumeration value="alkene oxidative cleavage" /> <!-- RXNO:0000344 -->
      <xs:enumeration value="heteroaryl N-alkylation" /> <!-- RXNO:0000345 -->
      <xs:enumeration value="oxacycle synthesis" /> <!-- RXNO:0000346 -->
      <xs:enumeration value="azacycle synthesis" /> <!-- RXNO:0000347 -->
      <xs:enumeration value="thiacycle synthesis" /> <!-- RXNO:0000348 -->
      <xs:enumeration value="heterocycle synthesis" /> <!-- RXNO:0000349 -->
      <xs:enumeration value="alkyne reduction to alkane" /> <!-- RXNO:0000350 -->
      <xs:enumeration value="aryl reduction to cycloalkyl" /> <!-- RXNO:0000351 -->
      <xs:enumeration value="heteroaryl reduction to saturated heterocycle" /> <!-- RXNO:0000352 -->
      <xs:enumeration value="alcohol oxidation to carboxylic acid" /> <!-- RXNO:0000353 -->
      <xs:enumeration value="benzylic oxidation" /> <!-- RXNO:0000354 -->
      <xs:enumeration value="allylic oxidation" /> <!-- RXNO:0000355 -->
      <xs:enumeration value="Jones oxidation" /> <!-- RXNO:0000356 -->
      <xs:enumeration value="N-acylation to amide" /> <!-- RXNO:0000357 -->
      <xs:enumeration value="N-acylation to urea" /> <!-- RXNO:0000358 -->
      <xs:enumeration value="N-acylation to carbamate" /> <!-- RXNO:0000359 -->
      <xs:enumeration value="O-acylation to ester" /> <!-- RXNO:0000360 -->
      <xs:enumeration value="Pinner reaction" /> <!-- RXNO:0000361 -->
      <xs:enumeration value="nitrile alcoholysis" /> <!-- RXNO:0000362 -->
      <xs:enumeration value="amide to imidoyl chloride conversion" /> <!-- RXNO:0000363 -->
      <xs:enumeration value="alcohol to halide conversion" /> <!-- RXNO:0000364 -->
      <xs:enumeration value="carboxylic acid to acid chloride conversion" /> <!-- RXNO:0000365 -->
      <xs:enumeration value="nitrile to acid conversion" /> <!-- RXNO:0000366 -->
      <xs:enumeration value="carbonyl compound to imine conversion" /> <!-- RXNO:0000367 -->
      <xs:enumeration value="Crabbé homologation" /> <!-- RXNO:0000368 -->
      <xs:enumeration value="Friedel-Crafts reaction" /> <!-- RXNO:0000369 -->
      <xs:enumeration value="Demko-Sharpless reaction" /> <!-- RXNO:0000370 -->
      <xs:enumeration value="Griess reaction" /> <!-- RXNO:0000371 -->
      <xs:enumeration value="heteroaryl N-arylation" /> <!-- RXNO:0000372 -->
      <xs:enumeration value="functional group addition step" /> <!-- RXNO:0000373 -->
      <xs:enumeration value="Chan-Lam coupling" /> <!-- RXNO:0000374 -->
      <xs:enumeration value="Eschweiler-Clarke methylation" /> <!-- RXNO:0000376 -->
      <xs:enumeration value="Scholl reaction" /> <!-- RXNO:0000377 -->
      <xs:enumeration value="intramolecular Scholl reaction" /> <!-- RXNO:0000378 -->
      <xs:enumeration value="intermolecular Scholl reaction" /> <!-- RXNO:0000379 -->
      <xs:enumeration value="Robinson annulation" /> <!-- RXNO:0000380 -->
      <xs:enumeration value="Tiffeneau-Demjanov rearrangement" /> <!-- RXNO:0000381 -->
      <xs:enumeration value="Demjanov rearrangement" /> <!-- RXNO:0000382 -->
      <xs:enumeration value="cyclic alpha-haloketone Favorskii rearrangement" /> <!-- RXNO:0000384 -->
      <xs:enumeration value="Favorskii rearrangement" /> <!-- RXNO:0000385 -->
      <xs:enumeration value="Wallach degradation" /> <!-- RXNO:0000386 -->
      <xs:enumeration value="Seyferth-Gilbert homologation" /> <!-- RXNO:0000387 -->
      <xs:enumeration value="Seyferth-Gilbert aldehyde homologation" /> <!-- RXNO:0000388 -->
      <xs:enumeration value="Seyferth-Gilbert ketone homologation" /> <!-- RXNO:0000389 -->
      <xs:enumeration value="Seyferth-Gilbert-Bestmann homologation" /> <!-- RXNO:0000390 -->
      <xs:enumeration value="Knorr pyrazole synthesis" /> <!-- RXNO:0000391 -->
      <xs:enumeration value="pyrazole synthesis" /> <!-- RXNO:0000392 -->
      <xs:enumeration value="quinoline synthesis" /> <!-- RXNO:0000393 -->
      <xs:enumeration value="Knorr quinoline synthesis" /> <!-- RXNO:0000394 -->
      <xs:enumeration value="indole synthesis" /> <!-- RXNO:0000395 -->
      <xs:enumeration value="Larock indole synthesis" /> <!-- RXNO:0000396 -->
      <xs:enumeration value="Pechmann pyrazole synthesis" /> <!-- RXNO:0000397 -->
      <xs:enumeration value="benzimidazole synthesis" /> <!-- RXNO:0000398 -->
      <xs:enumeration value="Phillips benzimidazole synthesis" /> <!-- RXNO:0000399 -->
      <xs:enumeration value="pyrimidine synthesis" /> <!-- RXNO:0000400 -->
      <xs:enumeration value="triazine synthesis" /> <!-- RXNO:0000401 -->
      <xs:enumeration value="Pinner pyrimidine synthesis" /> <!-- RXNO:0000402 -->
      <xs:enumeration value="Pinner triazine synthesis" /> <!-- RXNO:0000403 -->
      <xs:enumeration value="oxa-Pictet-Spengler reaction" /> <!-- RXNO:0000404 -->
      <xs:enumeration value="Prilezhaev epoxidation" /> <!-- RXNO:0000405 -->
      <xs:enumeration value="Appel halogenation" /> <!-- RXNO:0000406 -->
      <xs:enumeration value="Appel iodination" /> <!-- RXNO:0000407 -->
      <xs:enumeration value="Appel chlorination" /> <!-- RXNO:0000408 -->
      <xs:enumeration value="Appel bromination" /> <!-- RXNO:0000409 -->
      <xs:enumeration value="Hofmann rearrangement" /> <!-- RXNO:0000410 -->
      <xs:enumeration value="Hofmann reaction" /> <!-- RXNO:0000411 -->
      <xs:enumeration value="Newman-Kwart rearrangement" /> <!-- RXNO:0000412 -->
      <xs:enumeration value="Zincke nitration" /> <!-- RXNO:0000413 -->
      <xs:enumeration value="haloethanoate ester-aldehyde Darzens reaction" /> <!-- RXNO:0000414 -->
      <xs:enumeration value="haloethanoate ester-ketone Darzens reaction" /> <!-- RXNO:0000415 -->
      <xs:enumeration value="phthalimide protection" /> <!-- RXNO:0000418 -->
      <xs:enumeration value="phthalimide deprotection" /> <!-- RXNO:0000419 -->
      <xs:enumeration value="Kröhnke pyridine synthesis" /> <!-- RXNO:0000420 -->
      <xs:enumeration value="Gattermann chlorination" /> <!-- RXNO:0000421 -->
      <xs:enumeration value="Gattermann bromination" /> <!-- RXNO:0000422 -->
      <xs:enumeration value="aldehyde Barbier reaction" /> <!-- RXNO:0000426 -->
      <xs:enumeration value="ketone Barbier reaction" /> <!-- RXNO:0000427 -->
      <xs:enumeration value="pivaloyl protection" /> <!-- RXNO:0000428 -->
      <xs:enumeration value="pivaloyl deprotection" /> <!-- RXNO:0000429 -->
      <xs:enumeration value="hydroxy group deprotection" /> <!-- RXNO:0000430 -->
      <xs:enumeration value="carboxylic acid to primary alcohol reduction" /> <!-- RXNO:0000431 -->
      <xs:enumeration value="tert-butyl protection" /> <!-- RXNO:0000432 -->
      <xs:enumeration value="carboxy group deprotection" /> <!-- RXNO:0000433 -->
      <xs:enumeration value="tert-butyl ester deprotection" /> <!-- RXNO:0000434 -->
      <xs:enumeration value="methyl ester deprotection" /> <!-- RXNO:0000435 -->
      <xs:enumeration value="ethyl ester deprotection" /> <!-- RXNO:0000436 -->
      <xs:enumeration value="molecular transformation objective" /> <!-- RXNO:0000437 -->
      <xs:enumeration value="molecular skeleton cleaving objective" /> <!-- RXNO:0000438 -->
      <xs:enumeration value="molecular ring formation objective" /> <!-- RXNO:0000439 -->
      <xs:enumeration value="molecular skeleton joining objective" /> <!-- RXNO:0000440 -->
      <xs:enumeration value="molecular rearrangement objective" /> <!-- RXNO:0000441 -->
      <xs:enumeration value="functional modification objective" /> <!-- RXNO:0000442 -->
      <xs:enumeration value="Sakurai reaction" /> <!-- RXNO:0000443 -->
      <xs:enumeration value="Fries rearrangement" /> <!-- RXNO:0000444 -->
      <xs:enumeration value="ortho-Fries rearrangement" /> <!-- RXNO:0000445 -->
      <xs:enumeration value="para-Fries rearrangement" /> <!-- RXNO:0000446 -->
      <xs:enumeration value="Duff reaction" /> <!-- RXNO:0000447 -->
      <xs:enumeration value="molecular chain lengthening objective" /> <!-- RXNO:0000448 -->
      <xs:enumeration value="molecular ring breaking objective" /> <!-- RXNO:0000449 -->
      <xs:enumeration value="molecular ring contraction objective" /> <!-- RXNO:0000450 -->
      <xs:enumeration value="aldehyde Sakurai reaction" /> <!-- RXNO:0000451 -->
      <xs:enumeration value="ketone Sakurai reaction" /> <!-- RXNO:0000452 -->
      <xs:enumeration value="functional group modification objective" /> <!-- RXNO:0000453 -->
      <xs:enumeration value="end-of-chain chain shortening objective" /> <!-- RXNO:0000454 -->
      <xs:enumeration value="functional reduction objective" /> <!-- RXNO:0000455 -->
      <xs:enumeration value="addition objective" /> <!-- RXNO:0000456 -->
      <xs:enumeration value="molecular ring expansion objective" /> <!-- RXNO:0000457 -->
      <xs:enumeration value="molecular ring rearrangement objective" /> <!-- RXNO:0000458 -->
      <xs:enumeration value="acetoacetic ester synthesis" /> <!-- RXNO:0000459 -->
      <xs:enumeration value="intramolecular acyloin condensation" /> <!-- RXNO:0000460 -->
      <xs:enumeration value="intermolecular acyloin condensation" /> <!-- RXNO:0000461 -->
      <xs:enumeration value="molecular extrusion objective" /> <!-- RXNO:0000462 -->
      <xs:enumeration value="molecular fragmentation objective" /> <!-- RXNO:0000463 -->
      <xs:enumeration value="Pauson-Khand reaction" /> <!-- RXNO:0000464 -->
      <xs:enumeration value="fused-ring-system formation objective" /> <!-- RXNO:0000465 -->
      <xs:enumeration value="polymerisation objective" /> <!-- RXNO:0000466 -->
      <xs:enumeration value="Algar-Flynn-Oyamada reaction" /> <!-- RXNO:0000467 -->
      <xs:enumeration value="molecular substitution objective" /> <!-- RXNO:0000468 -->
      <xs:enumeration value="Allan-Robinson flavone synthesis" /> <!-- RXNO:0000470 -->
      <xs:enumeration value="Allan-Robinson isoflavone synthesis" /> <!-- RXNO:0000471 -->
      <xs:enumeration value="Amadori rearrangement" /> <!-- RXNO:0000472 -->
      <xs:enumeration value="Arens-van Dorp synthesis" /> <!-- RXNO:0000473 -->
      <xs:enumeration value="Auwers synthesis" /> <!-- RXNO:0000474 -->
      <xs:enumeration value="Allan-Robinson reaction" /> <!-- RXNO:0000475 -->
      <xs:enumeration value="Meyer-Schuster rearrangement" /> <!-- RXNO:0000476 -->
      <xs:enumeration value="Rupe rearrangement" /> <!-- RXNO:0000477 -->
      <xs:enumeration value="Still-Gennari modification" /> <!-- RXNO:0000478 -->
      <xs:enumeration value="olefination" /> <!-- RXNO:0000479 -->
      <xs:enumeration value="Tebbe olefination" /> <!-- RXNO:0000480 -->
      <xs:enumeration value="Myers-Saito cyclisation" /> <!-- RXNO:0000481 -->
      <xs:enumeration value="Schmittel cyclisation" /> <!-- RXNO:0000482 -->
      <xs:enumeration value="Baudisch reaction" /> <!-- RXNO:0000483 -->
      <xs:enumeration value="deprotection objective" /> <!-- RXNO:0000484 -->
      <xs:enumeration value="protection objective" /> <!-- RXNO:0000485 -->
      <xs:enumeration value="molecular skeleton elimination objective" /> <!-- RXNO:0000486 -->
      <xs:enumeration value="molecular skeleton insertion objective" /> <!-- RXNO:0000487 -->
      <xs:enumeration value="joining with rearrangement objective" /> <!-- RXNO:0000488 -->
      <xs:enumeration value="functional group addition objective" /> <!-- RXNO:0000489 -->
      <xs:enumeration value="functional oxidation objective" /> <!-- RXNO:0000490 -->
      <xs:enumeration value="interrupted Nazarov cyclisation" /> <!-- RXNO:0000491 -->
      <xs:enumeration value="Bamberger rearrangement" /> <!-- RXNO:0000492 -->
      <xs:enumeration value="Bart reaction" /> <!-- RXNO:0000493 -->
      <xs:enumeration value="Bartoli indole synthesis" /> <!-- RXNO:0000494 -->
      <xs:enumeration value="Barton olefination" /> <!-- RXNO:0000495 -->
      <xs:enumeration value="Barton-Zard reaction" /> <!-- RXNO:0000496 -->
      <xs:enumeration value="pyrrole synthesis" /> <!-- RXNO:0000497 -->
      <xs:enumeration value="Béchamp reduction" /> <!-- RXNO:0000498 -->
      <xs:enumeration value="Beirut reaction" /> <!-- RXNO:0000499 -->
      <xs:enumeration value="Bénary reaction" /> <!-- RXNO:0000500 -->
      <xs:enumeration value="Feist-Bénary synthesis" /> <!-- RXNO:0000501 -->
      <xs:enumeration value="Boulton-Katritzky rearrangement" /> <!-- RXNO:0000502 -->
      <xs:enumeration value="monocyclic Boulton-Katritzky rearrangement" /> <!-- RXNO:0000503 -->
      <xs:enumeration value="bicyclic Boulton-Katritzky rearrangement" /> <!-- RXNO:0000504 -->
      <xs:enumeration value="Mukaiyama-Hoshino method" /> <!-- RXNO:0000505 -->
      <xs:enumeration value="Nef synthesis" /> <!-- RXNO:0000506 -->
      <xs:enumeration value="Krapcho decarboxylation" /> <!-- RXNO:0000507 -->
      <xs:enumeration value="Cadogan cyclization" /> <!-- RXNO:0000508 -->
      <xs:enumeration value="Cadogan indole synthesis" /> <!-- RXNO:0000509 -->
      <xs:enumeration value="Benkeser reduction" /> <!-- RXNO:0000510 -->
      <xs:enumeration value="Madelung indole synthesis" /> <!-- RXNO:0000511 -->
      <xs:enumeration value="Smith indole synthesis" /> <!-- RXNO:0000512 -->
      <xs:enumeration value="Mumm rearrangement" /> <!-- RXNO:0000513 -->
      <xs:enumeration value="Chapman rearrangement" /> <!-- RXNO:0000514 -->
      <xs:enumeration value="Bergmann azlactone peptide synthesis" /> <!-- RXNO:0000515 -->
      <xs:enumeration value="Bergmann degradation" /> <!-- RXNO:0000516 -->
      <xs:enumeration value="terminal amino-acid residue cleaving reaction" /> <!-- RXNO:0000517 -->
      <xs:enumeration value="acridine synthesis" /> <!-- RXNO:0000518 -->
      <xs:enumeration value="Bernthsen acridine synthesis" /> <!-- RXNO:0000519 -->
      <xs:enumeration value="pyridine synthesis" /> <!-- RXNO:0000520 -->
      <xs:enumeration value="carbazole synthesis" /> <!-- RXNO:0000521 -->
      <xs:enumeration value="Betti reaction" /> <!-- RXNO:0000522 -->
      <xs:enumeration value="Bischler-Möhlau indole synthesis" /> <!-- RXNO:0000523 -->
      <xs:enumeration value="Camps quinoline synthesis" /> <!-- RXNO:0000524 -->
      <xs:enumeration value="Castro-Stephens coupling" /> <!-- RXNO:0000525 -->
      <xs:enumeration value="Chichibabin pyridine synthesis" /> <!-- RXNO:0000526 -->
      <xs:enumeration value="Chichibabin reaction" /> <!-- RXNO:0000527 -->
      <xs:enumeration value="Bodroux reaction" /> <!-- RXNO:0000528 -->
      <xs:enumeration value="Bogert-Cook synthesis" /> <!-- RXNO:0000529 -->
      <xs:enumeration value="Bohn-Schmidt reaction" /> <!-- RXNO:0000530 -->
      <xs:enumeration value="Boord olefin synthesis" /> <!-- RXNO:0000531 -->
      <xs:enumeration value="Borsche-Drechsel cyclisation" /> <!-- RXNO:0000532 -->
      <xs:enumeration value="Bouveault aldehyde synthesis" /> <!-- RXNO:0000533 -->
      <xs:enumeration value="Bradsher cyclisation" /> <!-- RXNO:0000534 -->
      <xs:enumeration value="Bradsher reaction" /> <!-- RXNO:0000535 -->
      <xs:enumeration value="Parham cyclisation" /> <!-- RXNO:0000536 -->
      <xs:enumeration value="Quelet reaction" /> <!-- RXNO:0000537 -->
      <xs:enumeration value="Chugaev reaction" /> <!-- RXNO:0000538 -->
      <xs:enumeration value="Cope elimination" /> <!-- RXNO:0000539 -->
      <xs:enumeration value="Sugasawa reaction" /> <!-- RXNO:0000540 -->
      <xs:enumeration value="palladium-catalysed Kumada coupling" /> <!-- RXNO:0000541 -->
      <xs:enumeration value="nickel-catalysed Kumada coupling" /> <!-- RXNO:0000542 -->
      <xs:enumeration value="Eastwood reaction" /> <!-- RXNO:0000543 -->
      <xs:enumeration value="Saegusa oxidation" /> <!-- RXNO:0000544 -->
      <xs:enumeration value="Sandmeyer diphenylurea isatin synthesis" /> <!-- RXNO:0000545 -->
      <xs:enumeration value="Sandmeyer isonitrosoacetanilide isatin synthesis" /> <!-- RXNO:0000546 -->
      <xs:enumeration value="Sarett oxidation" /> <!-- RXNO:0000547 -->
      <xs:enumeration value="Sarett primary alcohol oxidation" /> <!-- RXNO:0000548 -->
      <xs:enumeration value="Sarett secondary alcohol oxidation" /> <!-- RXNO:0000549 -->
      <xs:enumeration value="Collins oxidation" /> <!-- RXNO:0000550 -->
      <xs:enumeration value="reductive imination" /> <!-- RXNO:0000551 -->
      <xs:enumeration value="Leuckart aldehyde reaction" /> <!-- RXNO:0000552 -->
      <xs:enumeration value="Leuckart ketone reaction" /> <!-- RXNO:0000553 -->
      <xs:enumeration value="Appel bromination with tetrabromomethane" /> <!-- RXNO:0000554 -->
      <xs:enumeration value="Appel bromination with bromine" /> <!-- RXNO:0000555 -->
      <xs:enumeration value="Corey-Fuchs terminal dibromoolefination" /> <!-- RXNO:0000556 -->
      <xs:enumeration value="obsolete: Heck-type reaction/cross-coupling" /> <!-- RXNO:0000557 -->
      <xs:enumeration value="obsolete: bromo Heck reaction/Liebeskind-Srogl coupling" /> <!-- RXNO:0000558 -->
      <xs:enumeration value="obsolete: chloro Heck reaction/Fukuyama coupling" /> <!-- RXNO:0000559 -->
      <xs:enumeration value="obsolete: iodo Heck reaction/chloride Finkelstein reaction" /> <!-- RXNO:0000560 -->
      <xs:enumeration value="obsolete: triflyloxy Heck reaction/bromide Finkelstein reaction" /> <!-- RXNO:0000561 -->
      <xs:enumeration value="obsolete: bromo Heck-type reaction/sulfonate ester Finkelstein reaction" /> <!-- RXNO:0000562 -->
      <xs:enumeration value="obsolete: chloro Heck-type reaction/Sandmeyer fluorination" /> <!-- RXNO:0000563 -->
      <xs:enumeration value="obsolete: acyclic Beckmann rearrangement/Sandmeyer chlorination" /> <!-- RXNO:0000564 -->
      <xs:enumeration value="obsolete: Baeyer–Emmerling indole synthesis/Sandmeyer bromination" /> <!-- RXNO:0000565 -->
      <xs:enumeration value="obsolete: bromo Sonogashira coupling/Sandmeyer iodination" /> <!-- RXNO:0000566 -->
      <xs:enumeration value="obsolete: bromo Suzuki coupling/iodo Heck reaction" /> <!-- RXNO:0000567 -->
      <xs:enumeration value="obsolete: bromo Suzuki-type coupling/triflyloxy Heck reaction " /> <!-- RXNO:0000568 -->
      <xs:enumeration value="obsolete: bromolactonization/bromo Heck-type reaction" /> <!-- RXNO:0000569 -->
      <xs:enumeration value="obsolete: chloro Sonogashira coupling/chloro Heck-type reaction" /> <!-- RXNO:0000570 -->
      <xs:enumeration value="obsolete: chloro Suzuki coupling/Heck-type reaction" /> <!-- RXNO:0000571 -->
      <xs:enumeration value="obsolete: chloro Suzuki-type coupling/bromo Heck reaction" /> <!-- RXNO:0000572 -->
      <xs:enumeration value="obsolete: chlorolactonization/chloro Heck reaction" /> <!-- RXNO:0000573 -->
      <xs:enumeration value="cyclic Beckmann rearrangement" /> <!-- RXNO:0000574 -->
      <xs:enumeration value="Dess-Martin aldehyde oxidation" /> <!-- RXNO:0000575 -->
      <xs:enumeration value="Dess-Martin ketone oxidation" /> <!-- RXNO:0000576 -->
      <xs:enumeration value="Friedlander quinoline synthesis" /> <!-- RXNO:0000577 -->
      <xs:enumeration value="Gewald reaction" /> <!-- RXNO:0000578 -->
      <xs:enumeration value="iodo Sonogashira coupling" /> <!-- RXNO:0000579 -->
      <xs:enumeration value="iodo Suzuki coupling" /> <!-- RXNO:0000580 -->
      <xs:enumeration value="iodo Suzuki-type coupling" /> <!-- RXNO:0000581 -->
      <xs:enumeration value="iodolactonization" /> <!-- RXNO:0000582 -->
      <xs:enumeration value="Niementowski quinazoline synthesis" /> <!-- RXNO:0000583 -->
      <xs:enumeration value="Niementowski quinoline synthesis" /> <!-- RXNO:0000584 -->
      <xs:enumeration value="Pomeranz–Fritsch reaction" /> <!-- RXNO:0000585 -->
      <xs:enumeration value="Steglich esterification" /> <!-- RXNO:0000586 -->
      <xs:enumeration value="triflyloxy Sonogashira coupling" /> <!-- RXNO:0000587 -->
      <xs:enumeration value="triflyloxy Suzuki coupling" /> <!-- RXNO:0000588 -->
      <xs:enumeration value="triflyloxy Suzuki-type coupling" /> <!-- RXNO:0000589 -->
      <xs:enumeration value="Wenker synthesis" /> <!-- RXNO:0000590 -->
      <xs:enumeration value="Hinsberg thiophene synthesis" /> <!-- RXNO:0000591 -->
      <xs:enumeration value="Suzuki-type coupling" /> <!-- RXNO:0000592 -->
      <xs:enumeration value="halolactonization" /> <!-- RXNO:0000593 -->
      <xs:enumeration value="Ciamician-Dennstedt rearrangement" /> <!-- RXNO:0000594 -->
      <xs:enumeration value="Claisen-Schmidt condensation" /> <!-- RXNO:0000595 -->
      <xs:enumeration value="obsolete: Combes quinoline synthesis/Conrad%E2%80%93Limpach_synthesis" /> <!-- RXNO:0000596 -->
      <xs:enumeration value="Corey-Bakshi-Shibata reduction" /> <!-- RXNO:0000597 -->
      <xs:enumeration value="Johnson-Corey-Chaykovsky reaction" /> <!-- RXNO:0000598 -->
      <xs:enumeration value="Johnson-Corey-Chaykovsky epoxide synthesis" /> <!-- RXNO:0000599 -->
      <xs:enumeration value="Johnson-Corey-Chaykovsky cyclopropane synthesis" /> <!-- RXNO:0000600 -->
      <xs:enumeration value="Johnson-Corey-Chaykovsky aziridine synthesis" /> <!-- RXNO:0000601 -->
      <xs:enumeration value="Johnson-Corey-Chaykovsky thiirane synthesis" /> <!-- RXNO:0000602 -->
      <xs:enumeration value="cross-coupling" /> <!-- RXNO:0000603 -->
      <xs:enumeration value="Liebeskind-Srogl coupling" /> <!-- RXNO:0000604 -->
      <xs:enumeration value="Fukuyama coupling" /> <!-- RXNO:0000605 -->
      <xs:enumeration value="chloride Finkelstein reaction" /> <!-- RXNO:0000606 -->
      <xs:enumeration value="bromide Finkelstein reaction" /> <!-- RXNO:0000607 -->
      <xs:enumeration value="sulfonate ester Finkelstein reaction" /> <!-- RXNO:0000608 -->
      <xs:enumeration value="Sandmeyer fluorination" /> <!-- RXNO:0000609 -->
      <xs:enumeration value="Sandmeyer chlorination" /> <!-- RXNO:0000610 -->
      <xs:enumeration value="Sandmeyer bromination" /> <!-- RXNO:0000611 -->
      <xs:enumeration value="Sandmeyer iodination" /> <!-- RXNO:0000612 -->
      <xs:enumeration value="imidazole synthesis" /> <!-- RXNO:0000613 -->
      <xs:enumeration value="indazole synthesis" /> <!-- RXNO:0000614 -->
      <xs:enumeration value="piperazine synthesis" /> <!-- RXNO:0000615 -->
      <xs:enumeration value="piperidine synthesis" /> <!-- RXNO:0000616 -->
      <xs:enumeration value="pyrrolidine synthesis" /> <!-- RXNO:0000617 -->
      <xs:enumeration value="Hofmann-Löffler-Freytag reaction" /> <!-- RXNO:0000618 -->
      <xs:enumeration value="Hofmann-Löffler-Freytag piperidine synthesis" /> <!-- RXNO:0000619 -->
      <xs:enumeration value="Hofmann-Löffler-Freytag pyrrolidine synthesis" /> <!-- RXNO:0000620 -->
      <xs:enumeration value="Hell-Volhard-Zelinsky reaction" /> <!-- RXNO:0000621 -->
      <xs:enumeration value="Meerwein-Ponndorf-Verley reduction of an aldehyde" /> <!-- RXNO:0000622 -->
      <xs:enumeration value="Meerwein-Ponndorf-Verley reduction of a ketone" /> <!-- RXNO:0000623 -->
      <xs:enumeration value="Heck-type reaction" /> <!-- RXNO:0000624 -->
      <xs:enumeration value="obsolete: bromo Heck reaction" /> <!-- RXNO:0000625 -->
      <xs:enumeration value="chloro Heck reaction" /> <!-- RXNO:0000626 -->
      <xs:enumeration value="iodo Heck reaction" /> <!-- RXNO:0000627 -->
      <xs:enumeration value="triflyloxy Heck reaction" /> <!-- RXNO:0000628 -->
      <xs:enumeration value="bromo Heck-type reaction" /> <!-- RXNO:0000629 -->
      <xs:enumeration value="chloro Heck-type reaction" /> <!-- RXNO:0000630 -->
      <xs:enumeration value="acyclic Beckmann rearrangement" /> <!-- RXNO:0000631 -->
      <xs:enumeration value="Baeyer–Emmerling indole synthesis" /> <!-- RXNO:0000632 -->
      <xs:enumeration value="bromo Sonogashira coupling" /> <!-- RXNO:0000633 -->
      <xs:enumeration value="bromo Suzuki coupling" /> <!-- RXNO:0000634 -->
      <xs:enumeration value="bromo Suzuki-type coupling" /> <!-- RXNO:0000635 -->
      <xs:enumeration value="bromolactonization" /> <!-- RXNO:0000636 -->
      <xs:enumeration value="chloro Sonogashira coupling" /> <!-- RXNO:0000637 -->
      <xs:enumeration value="chloro Suzuki coupling" /> <!-- RXNO:0000638 -->
      <xs:enumeration value="chloro Suzuki-type coupling" /> <!-- RXNO:0000639 -->
      <xs:enumeration value="chlorolactonization" /> <!-- RXNO:0000640 -->
      <xs:enumeration value="Conrad-Limpach cyclisation" /> <!-- RXNO:0000641 -->
      <xs:enumeration value="Combes quinoline synthesis" /> <!-- RXNO:0000642 -->
      <xs:enumeration value="protects" /> <!-- RXNO:0000416 -->
      <xs:enumeration value="deprotects" /> <!-- RXNO:0000417 -->
      <xs:enumeration value="has specified product" /> <!-- RXNO:0000423 -->
      <xs:enumeration value="has specified reactant" /> <!-- RXNO:0000424 -->
      <xs:enumeration value="has_catalyst" /> <!-- RXNO:0000425 -->
      <xs:enumeration value="has_intermediate" /> <!-- RXNO:0000469 -->
    </xs:restriction>
  </xs:simpleType>
</xs:schema>