- Search genes by
startsWith
instead ofcontains
. - Slightly larger default point size in gene/gene plots.
- Do not show cell types with no metacells in the 'Markers' tab (issue #161).
- Do not reorder tabs when they are set in the config file.
- Added an option to include metadata when downloading marker heatmap.
- Added "Enrichment type" toggle to the 'Markers' tab.
- Added an option to show only fitted genes in the projected fold tab.
- Moved "Order by" and "Force cell type" to left sidebar in the 'Markers' tab.
- Added "Order cell types by" option to the 'Markers' tab.
- Fix: legend did not appear in the 'Markers' tab when using
ggplot 3.5.0
.
- Added an option to order by metadata when 'force cell type' is FALSE.
- Added lateral/noisy labels to gene selectors.
- Multiple fixes:
- Fix: loading of light_version bundles was broken.
- Fix:
projection_point_size
andscatters_point_size
were not detected when added inother_params
. - Fix: import warned when there were metacells withour an edge when providing
default_graph
parameter.
About
tab is now the first in light-version bundles.
- Added an option to exclude lateral and noisy genes from marker heatmap.
- Added 'Load genes' and 'Save genes' buttons to the 'Markers' tab.
- Added 'Top correlated' widgets to metadata and gene modules.
- Added some missing package imports.
- Fix: plot limits were sometimes too low in differential expression plots.
- Added an option to sort gene heatmaps by metadata within each cell type.
- In 'Projection QC' tab, changed percentage of 'similar' to percentage of 'dissimilar' metacells.
- Fixed gene name colors in the 'Gene modules' tab.
- Fixed metadata colors at 2D projections (previously the breaks were simply ignored)
- Added an option to use disk for shiny caching (
see shiny_cache_dir
andshiny_cache_max_size
parameters increate_bundle
) - Fix: sidebar still showed spaces for excluded tabs.
- Added 'overwrite' parameter to
import_dataset
. - Fixed an edge case in which a cell type was not continuous in the markers heatmap order.
- Fix: atlas tab was not working after the new UMAP feature.
- Use corrected expression in the differential expression in the Query tab.
- Mark dissimilar metacells in metacell selectors.
- Added gene colors legend to the 'Markers' tab.
- Added 'any' cell type to gene metadata table at Query tab.
- Added a value box with % of fitted genes out of atlas markers.
- Query tab improvements: added a correction factor line and an option to show only fitted genes.
- Added UMAP computation given anchor genes to the 'Manifold' tab.
- Added
Sample types
plot to theSamples
tab. - Fixed a few bugs in the
Samples
tab.
- Fix: fitted gene plot was not shown when 'corrected_factor' was missing from the input data.
- Changed zero-fold per gene plot to show expression vs zero-fold.
- Added two static plots to About tab.
- Added "top-correlated" panel to "Cell types" tab.
- Added "inner-std" plot to QC panel.
- Added "Stdev-fold" tab.
- Added "Projection QC" tab
- Fix: differential expression between metacells did not work with most recent version of
qs
. - Added Lasso selection in Annotation and Differential Expression tabs.
- Added "# of metacells with significant inner-fold" to the "QC" tab.
- Filter lateral/noisy genes from diff expression plots.
- Annotate genes with their lateral/noisy status + gene modules.
- Fixed import according to newest metacells version.
- Added the 'QC' tab. Please re-import your dataset in order to enable it.
- Moved some of 'gene/gene' and 'projection' controls to below the plot.
- Added 'excluded_tabs' to the config file.
- Added a footer with MCView and metacells versions.
- Some modifications to the 'Genes' tab layout.
- Added an option to color the 2D projection by an axis from the Gene/Gene plot.
- Added QC metrics to the manifold tab.
- Fix: import_cell_metadata was overwriting existing metadata
- Fix: import crashed when metacell_types had missing colors
- Use new
metacells
version. Note that oldanndata
objects will not work with this version without conversion. - Added an option to bundle a 'light' version without the option to change the genes on heatmaps.
- Fixed resolution of heatmap plots.
- Added a 'rename' modal to the 'Annotate' tab.
- Fixed order of negative correlations in the left panels. Fixes #127.
- Added an option to use 'gene_names' parameter with atlas projection.
- Use the name of the dataset as title by default.
- Rasterized Type Prediction plot.
- Added tab selector.
- Runtime optimizations: load tabs only on click.
- Some css fixes.
- Changed default 'about' document.
- Added preloader spinner.
- Allow using
run_app
with the bundle folder. - Added cell metadata support for metacell1 import.
- Fix: clicking on a cell type on the manifold legend was sometimes not aligned with the gene/gene plot.
- Fix: categorical metadata tooltip was wrong in projection plots.
- Changed metacell selectors to search with "contains" instead of "startWith" behaviour.
- Add an option to add metacells to clipboard by number
- runtime optimizations: use virtualSelectInput
- Added support for gene modules ('Gene modules' tab).
- Added 'Outliers' tab.
- Added Clipboard functionality.
- Added support for alternative gene names.
- Added control over the number of clusters / whether to cluster at all in the import phase.
- Added new selection controls to Annotate tab ('Gears' symbol on the upper right of 'Metacell Annotation' box).
- Bug fix: heatmaps crashed when only a single gene was chosen.
- Bug fix: automatically color cell types missing from cell type colors file.
- Bug fix: Diff expr. crashed when there was only a single cell type.
- Bug fix: Wrong tooltip in metadata/metadata scatter plot.
- Bug fix: Annotation colors in markers heatmap were scaled relative to current zoom.
- Added control for marker selection parameters in
import_dataset
.
- Added support for atlas projections ('Atlas', 'Query' and 'Projected-fold' tabs)
- Added tooltip and interactive clicks to heatmaps ('Markers' and 'Projected-fold' tabs)
- Added zoom for heatmaps.
- Homogenize Annotate, Diff. Expr and Genes tabs.
- Added 'Cell types' tab.
- Added support for cell metadata using the 'Samples' tab.
- Allow coloring by categorical metadata annotations.
- Moved flow graphs to their own tab named 'Flow'.
create_project
andimport_dataset
now accept the config file parameters.- Added option to force x and y limits to be the same in gene/gene plots.
- Added an option to show x=y line in gene/gene plots.
- Added Metadata tab.
- Added Markers tab.
- Added inner-fold matrix to markers tab.
- Added an option to compare cell types on Metacell tab.
- Added a download button.
- Added a busy spinner.
create_project
now only takes a path (instead of path + project name)- implicitly create a project when importing
- import cell type annotation using a single file that contains both metacell types and cell type colors.
- Bug fixes: issues #48, #51, #52, #60, #62 and more.
- Changed gene selectors on the manifold tab to be on-demand (to reduce initialization time).
- Added (some) caching.
- A few bug fixes. See issues #36, #37, #38, #40, #41 and #42.
- First stable version.