diff --git a/ngff_zarr/detect_cli_io_backend.py b/ngff_zarr/detect_cli_io_backend.py
index 78cee7b..e72f1ea 100644
--- a/ngff_zarr/detect_cli_io_backend.py
+++ b/ngff_zarr/detect_cli_io_backend.py
@@ -21,7 +21,7 @@ def detect_cli_io_backend(input: List[str]) -> ConversionBackend:
 
     extension = "".join(Path(input[0]).suffixes).lower()
 
-    ngff_zarr_supported_extensions = (".zarr",)
+    ngff_zarr_supported_extensions = (".zarr", ".ome.zarr")
     if extension in ngff_zarr_supported_extensions:
         return ConversionBackend.NGFF_ZARR
 
diff --git a/test/test_detect_cli_input_backend.py b/test/test_detect_cli_input_backend.py
index 75e2c97..a4440f8 100644
--- a/test/test_detect_cli_input_backend.py
+++ b/test/test_detect_cli_input_backend.py
@@ -1,6 +1,16 @@
 from ngff_zarr import ConversionBackend, detect_cli_io_backend
 
 
+def test_detect_ngff_zarr_input_backend():
+    extension = ".ome.zarr"
+    backend = detect_cli_io_backend(
+        [
+            f"file{extension}",
+        ]
+    )
+    assert backend == ConversionBackend.NGFF_ZARR
+
+
 def test_detect_itk_input_backend():
     extension = ".nrrd"
     backend = detect_cli_io_backend(