This is an example of generating head CT perfusion map from series of CT scans by cSVD-based deconvolution in Python.
THE ALGORITHM HAS NOT BEEN VALIDATED AND IS NOT INTENDED FOR CLINICAL USAGE
Refer to tutorial.ipynb for more.
cSVD deconvolution algorithm was implemented based on these works:
- https://github.com/SethLirette/CTP
- https://github.com/marcocastellaro/dsc-mri-toolbox
- Zanderigo F, Bertoldo A, Pillonetto G, Cobelli Ast C. Nonlinear stochastic regularization to characterize tissue residue function in bolus-tracking MRI: assessment and comparison with SVD, block-circulant SVD, and Tikhonov. IEEE Trans Biomed Eng. 2009 May;56(5):1287-97. doi: 10.1109/TBME.2009.2013820. Epub 2009 Feb 2. PMID: 19188118.