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I have a list of compounds with associated liver toxicity mechanisms - free text explanations of how the compound causes toxicity, from papers, etc. Each mechanism is annotated with a set of TXPO id's. For example, one entry includes the following:
Mechanism: Compound causes impaired synthesis of protein, depression of levels of ATP, or alteration of DNA or RNA , and direct destruction of hepatocyte membranes which lead to hepatotoxicity
TXPO keywords: hypofunction of protein synthesis|ATP depletion|mutation|hepatotoxic agent
I would like to further label the TXPO ID's as being associated with a particular toxic course. Is there a way I can obtain a list of each TXPO term that is associated with each toxic course? I am very new to working with ontologies and the toxpilot system. Any help would be greatly appreciated!
Thanks,
Amanda
The text was updated successfully, but these errors were encountered:
Hi,
I have a list of compounds with associated liver toxicity mechanisms - free text explanations of how the compound causes toxicity, from papers, etc. Each mechanism is annotated with a set of TXPO id's. For example, one entry includes the following:
Mechanism: Compound causes impaired synthesis of protein, depression of levels of ATP, or alteration of DNA or RNA , and direct destruction of hepatocyte membranes which lead to hepatotoxicity
TXPO ids: TXPO_0001958|TXPO_0000485|TXPO_0001985|CHEBI_50908
TXPO keywords: hypofunction of protein synthesis|ATP depletion|mutation|hepatotoxic agent
I would like to further label the TXPO ID's as being associated with a particular toxic course. Is there a way I can obtain a list of each TXPO term that is associated with each toxic course? I am very new to working with ontologies and the toxpilot system. Any help would be greatly appreciated!
Thanks,
Amanda
The text was updated successfully, but these errors were encountered: