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NEWS
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CHANGES IN VERSION 1.17.1
-------------------------
- Re-wrote the internal function to convert "Case C" long format-type input
to "Case A" short-form input. The new function uses dplyr to make it much
more readable and fixes a possible conversion error when extra columns are
included, but not named as grouping variables.
- Required "treatment" column in input data to match the GRcalculator app.
CHANGES IN VERSION 1.3.3
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- Renamed column "GR" to "GRvalue" for GR value table to match other code.
- Fixed erroneous error message in division rate GR value calculation
CHANGES IN VERSION 1.3.2
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- Renamed some curve parameters for the relative cell count curve
- changed "IC" to "rel_cell".
- Changed GRdrawDRC function parameter option for dose response curves based
on relative cell counts from 'metric = "IC"' to 'metric = "rel_cell"'.
- Changed GRinf (and Einf) value to the minimum of the mean GR values
(relative cell count) at the two highest concentrations tested for the
case of horizontal line fits (same as GRmax).
- Changed GRmax (and Emax) so that in the case of averaging over multiple
conditions, the value taken is the minimum of the mean of GR values
(relative cell count) at the two highest concentrations instead of the
absolute minimum GR value at these concentrations.
- "duration" column in input changed to "treatment_duration" to match the
nomenclature in other code.
- Added calculation of GR values from division rates for Case "C"
CHANGES IN VERSION 1.3.1
-------------------------
- Added calculation of GR values from division rates for Case "A"
- now accepts columns "duration" and "division_time" instead of
"cell_count__time0"
- Added a few parameters to calculation
- "control_cell_doublings" is the number of cell doublings that occur
in the control population over the assay, calculated either from
initial and final cell counts or given division rate and time of assay.
- "concentration_points" is the number of different concentrations used
in an experiment