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Amazing news - Astrid von Mentzer, PI of von Mentzer Lab, has recieved a huge grant and joined as a DDLS-fellow. We are seeking individuals (PhD-students and postdocs) with a keen interest in computational biology, particularly in the areas of microbial genomics and machine learning. For more info click here!
The von Mentzer Lab is a team of researchers at the University of Gothenburg, Sahlgrenska Academy dedicated to answering important questions in bacterial evolution using a combination of computational and experimental methodologies. We focus on bringing together publicly available big data, and collecting new data from collaborations worldwide with the aim to make our data and tools freely available and openly licensed for other researchers to use and extend our work.
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The research in the von Mentzer Lab is focused on the study of bacterial evolution, specifically the evolution of pathogenic E. coli, such as enterotoxgenic Escherichia coli (ETEC). One of the many virulence factors that bacteria express are adhesins, also called colonisation factors. These are proteinaceous outer membrane structures that allow tha bacteria to adhere to the host cells. In ETEC there is a battery of colonisation factors that we know quite little about. We use genomic approached to study sequenced E. coli genomes, including ETEC to investigate the diversity of these colonisation factors including their mobile genetic elements. In addition to viurlence genes, we have an interest in antibiotic resistance with the aim to investigate the plasmids carrying resistance genes and field that currently is expanding. The genomic findings guide the experimental approaches to investigate the functionality of, for example a putative colonisation factor.
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We have multiple on-going projects covering aspects of bacterial evolution with a focus on pathogenic E. coli. The data we use and generate is pushed to be open source and freely accessible. Are you interested in joining the team, contact Astrid von Mentzer and we can discuss further.
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We are a small team recently established at the Sahlgrenska Academy, Department of Microbiology and Immunology. We strive to build a diverse team where we emmbrace our differences and create space for innovation. We are funded by multiple funders, including the prestigous funders Knut and Alice Wallenberg (DDLS) and The Research Council. Additional funding comes from Sahlgrenska Academy, Åke Wiberg and Jeanssons Stiftelse.
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