diff --git a/boa/__init__.py b/boa/__init__.py
index e8cea0b5..03e3fb04 100644
--- a/boa/__init__.py
+++ b/boa/__init__.py
@@ -13,9 +13,11 @@
     load,
     load_abi,
     load_partial,
+    load_vyi,
     loads,
     loads_abi,
     loads_partial,
+    loads_vyi,
 )
 from boa.network import NetworkEnv
 from boa.precompile import precompile
diff --git a/boa/interpret.py b/boa/interpret.py
index 4447335f..17136d3c 100644
--- a/boa/interpret.py
+++ b/boa/interpret.py
@@ -8,6 +8,7 @@
 
 import vvm
 import vyper
+from vyper.ast.parse import parse_to_ast
 from vyper.cli.vyper_compile import get_search_paths
 from vyper.compiler.input_bundle import (
     ABIInput,
@@ -17,6 +18,7 @@
 )
 from vyper.compiler.phases import CompilerData
 from vyper.compiler.settings import Settings, anchor_settings
+from vyper.semantics.analysis.module import analyze_module
 from vyper.semantics.types.module import ModuleT
 from vyper.utils import sha256sum
 
@@ -194,6 +196,7 @@ def loads(
 def load_abi(filename: str, *args, name: str = None, **kwargs) -> ABIContractFactory:
     if name is None:
         name = Path(filename).stem
+    # TODO: pass filename to ABIContractFactory
     with open(filename) as fp:
         return loads_abi(fp.read(), *args, name=name, **kwargs)
 
@@ -202,6 +205,33 @@ def loads_abi(json_str: str, *args, name: str = None, **kwargs) -> ABIContractFa
     return ABIContractFactory.from_abi_dict(json.loads(json_str), name, *args, **kwargs)
 
 
+# load from .vyi file.
+# NOTE: substantially same interface as load_abi and loads_abi, consider
+# fusing them into load_interface?
+def load_vyi(filename: str, name: str = None) -> ABIContractFactory:
+    if name is None:
+        name = Path(filename).stem
+    with open(filename) as fp:
+        return loads_vyi(fp.read(), name=name, filename=filename)
+
+
+# load interface from .vyi file string contents.
+def loads_vyi(source_code: str, name: str = None, filename: str = None):
+    global _search_path
+
+    ast = parse_to_ast(source_code)
+
+    if name is None:
+        name = "VyperContract.vyi"
+
+    search_paths = get_search_paths(_search_path)
+    input_bundle = FilesystemInputBundle(search_paths)
+
+    module_t = analyze_module(ast, input_bundle, is_interface=True)
+    abi = module_t.interface.to_toplevel_abi_dict()
+    return ABIContractFactory(name, abi, filename=filename)
+
+
 def loads_partial(
     source_code: str,
     name: str = None,
diff --git a/tests/unitary/contracts/vyper/test_vyi.py b/tests/unitary/contracts/vyper/test_vyi.py
new file mode 100644
index 00000000..8269c9b2
--- /dev/null
+++ b/tests/unitary/contracts/vyper/test_vyi.py
@@ -0,0 +1,42 @@
+import pytest
+
+import boa
+
+FOO_CONTRACT = """
+@external
+def foo() -> uint256:
+    return 5
+"""
+
+FOO_INTERFACE = """
+@external
+def foo() -> uint256:
+    ...
+"""
+
+
+@pytest.fixture
+def foo_contract():
+    return boa.loads(FOO_CONTRACT)
+
+
+@pytest.fixture
+def foo_interface(foo_contract):
+    return boa.loads_vyi(FOO_INTERFACE).at(foo_contract.address)
+
+
+# from file
+@pytest.fixture
+def foo_interface2(foo_contract, tmp_path):
+    p = tmp_path / "foo.vyi"
+    with p.open("w") as f:
+        f.write(FOO_INTERFACE)
+    return boa.load_vyi(p).at(foo_contract.address)
+
+
+def test_foo_interface(foo_interface):
+    assert foo_interface.foo() == 5
+
+
+def test_foo_interface2(foo_interface2):
+    assert foo_interface2.foo() == 5