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Support for Mammal320k array? #142

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andrewjkwok opened this issue Jan 24, 2024 · 0 comments
Open

Support for Mammal320k array? #142

andrewjkwok opened this issue Jan 24, 2024 · 0 comments

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@andrewjkwok
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Thanks for the fantastic package.

My team has run some samples on a Mammal320k array i.e. the Mouse285k array + the Horvath Mammal40k array. I was wondering whether sesame would support this directly, or whether it is recommended that I split the 285k and 40k probes to analyze separately?

For example for differential methylation modeling with the DML and DMR functions, when I try to use the DMR function to merge the individual CpG sites into regions, I need to provide a platform. I am able to run the code specifying platform="MM285" but I am not sure how the software is handling information of the Mammal40k probes?

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