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Update site/NEWS
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ncborcherding committed May 4, 2024
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8 changes: 4 additions & 4 deletions NEWS.md
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* Replace numerical indexing with name indexing for ```loadContigs()```
* ```combineBCR()``` and ```combineTCR()``` no allow for unproductive contig inclusions with new **filterNonproductive** parameter.
* ```combineBCR()``` will now prompt user if **samples** is not included instead of erroring.
* Added base threshold by length for internal ```.lvcCmpare()```-
* Ensured internal ```.lvcompare()``` only looks at first set of sequences in multi-sequence chain.
* Added base threshold by length for internal ```.lvCompare()```
* Ensured internal ```.lvCompare()``` only looks at first set of sequences in multi-sequence chain.
* Fixed bug in exporting graph for ```clonaCluster()```
* Fixed conflict in functions between igraph and dplyr packages

# scRepertoire VERSION 2.0.2

## UNDERLYING CHANGES

*```clonalOccupy()``` rewrite counting and NA handling
* ```clonalOccupy()``` rewrite counting and NA handling

# scRepertoire VERSION 2.0.1

## UNDERLYING CHANGES

*```clonalOverlay()``` arguments now cutpoint and use cut.category to select either clonalProportion or clonalFrequency
* ```clonalOverlay()``` arguments now cutpoint and use cut.category to select either clonalProportion or clonalFrequency

# scRepertoire VERSION 2.0.0 (2024-01-10)

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3 changes: 2 additions & 1 deletion inst/pkgdown.yml
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Expand Up @@ -18,7 +18,8 @@ articles:
Running_Escape: Running_Escape.html
SC_Visualizations: SC_Visualizations.html
Trex: Trex.html
last_built: 2024-02-24T16:17Z
vignette: vignette.html
last_built: 2024-05-04T10:19Z
urls:
reference: https://www.borch.dev/uploads/scRepertoire/reference
article: https://www.borch.dev/uploads/scRepertoire/articles
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10 changes: 10 additions & 0 deletions vignettes/articles/Running_Escape.Rmd
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Expand Up @@ -218,6 +218,15 @@ ggplot(data = as.data.frame(enrichment.scores),
theme_classic() +
theme()
```
Multi-core support is for all methods is available through [BiocParallel](https://bioconductor.org/packages/release/bioc/html/BiocParallel.html). To add more cores, use the argument **BPPARAM** to ```escape.matrix()```. Here we will use the ```SnowParam()``` for it's support across platforms and explicitly call 2 workers (or cores).

```{r tidy=FALSE, eval=FALSE}
enrichment.scores <- escape.matrix(scRep_example,
gene.sets = GS.hallmark,
groups = 5000,
min.size = 5,
BPPARAM = SnowParam(workers = 2))
```

## runEscape

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assay = "escape.ssGSEA",
gene.set = "HALLMARK-IL2-STAT5-SIGNALING")
```

We can get the relative position of individual cells along the x-axis using the **add.rug** parameter.

```{r tidy=FALSE}
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