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cactuskid committed Aug 30, 2024
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4 changes: 4 additions & 0 deletions docs/.buildinfo
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# Sphinx build info version 1
# This file hashes the configuration used when building these files. When it is not found, a full rebuild will be done.
config: 68666ed7422b1e0bf84ee532afdab9b6
tags: 645f666f9bcd5a90fca523b33c5a78b7
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76 changes: 76 additions & 0 deletions docs/_sources/index.rst.txt
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HogProf
=====================

- HogProf is an extensible and tunable approach to phylogenetic profiling using orthology data. It is powered by minhash based datastructures and computationally efficient.
- Still under major development and may change.

.. toctree::
:maxdepth: 2
:caption: Contents:

installation
usage
troubleshooting
credits

Installation
------------

To install My Project, run the following command:

Using pip


.. code-block:: bash
$ pip install hogprof
Or from github
.. code-block:: bash
$ git clone https://github.com/DessimozLab/HogProf.git
$ pip install -r pipreqs.txt .

Quickstart
-----

To use the library we need an OMA instance's HDF5 file containing HOG info and some accesory files.

.. code-block:: bash
$ mkdir YourOmaDirectory
$ cd YourOmaDirectory
$ wget https://omabrowser.org/All/OmaServer.h5
$ wget https://omabrowser.org/All/oma-go.txt.gz
Let's create a directory for the phylogenetic rpfiling database were going to make.


.. code-block:: bash
$ mkdir YourDBDirectory
Ok. We're ready! Now let's compile a database containing all HOGs and our desired taxonomic levels using default settings. Launch the lshbuilder.
dbtypes available on the command line are : all , plants , archaea, bacteria , eukarya , protists , fungi , metazoa and vertebrates. These will use the NCBI taxonomy as a tree to annotate events in different gene family's histories.

.. code-block:: bash
$python lshbuilder.py --outpath YourHogProfDirectory --dbtype all --OMA YourOmaDirectory/OmaServer.h5 --nthreads numberOfCPUcores
This should build a taxonomic tree for the genomes contained in the release and then calculate enhanced phylogenies for all HOGs in OMA.
Once the database is completed it can be interogated using a profiler object. Construction and usage of this object should be done using a python script or notebook.


.. code-block:: python
import HogProf
myproject.do_x()
Troubleshooting
---------------


If you encounter any issues while using My Project, please file a bug report on our GitHub repository: https://github.com/user/repo/issues


Credits
-------

My Project was created by John Doe.
123 changes: 123 additions & 0 deletions docs/_static/_sphinx_javascript_frameworks_compat.js
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