Skip to content

Commit

Permalink
Merge pull request #665 from josefoviedo/master
Browse files Browse the repository at this point in the history
Update deduplication.md
  • Loading branch information
FelixKrueger authored Mar 27, 2024
2 parents acf965c + 02efb90 commit 37e2cad
Show file tree
Hide file tree
Showing 2 changed files with 2 additions and 2 deletions.
2 changes: 1 addition & 1 deletion docs/bismark/deduplication.md
Original file line number Diff line number Diff line change
Expand Up @@ -26,7 +26,7 @@ In addition to chromosome, start (and end position for paired-end libraries) pos
MISEQ:14:000000000-A55D0:1:1101:18024:2858_1:N:0:CTCCT
```

This option option is equivalent to using [UmiBam](https://github.com/FelixKrueger/Umi-Grinder) in the following mode:
This option is equivalent to using [UmiBam](https://github.com/FelixKrueger/Umi-Grinder) in the following mode:
`UmiBam --umi input.bam`, however UmiBam has additional functionality such as a double UMI feature or the option to allow mismatches in the UMI(s).

### Deduplication of multiple files of the same library
Expand Down
2 changes: 1 addition & 1 deletion docs/bismark/methylation_extraction.md
Original file line number Diff line number Diff line change
Expand Up @@ -89,7 +89,7 @@ The main difference to the `bedGraph` or `coverage` output is that **every** cyt

#### GpC methylation assessment: Context-specific methylation summary report

Every time `coverage2cyyosine` is run, the counts for each cytosine context are recorded and printed to a special file called `*.cytosine_context_summary.txt` for each input coverage file.
Every time `coverage2cytosine` is run, the counts for each cytosine context are recorded and printed to a special file called `*.cytosine_context_summary.txt` for each input coverage file.

The report ([introduced here](https://github.com/FelixKrueger/Bismark/issues/321)) looks at 2 bp downstream, as well as 1 bp upstream of the cytosine taking part in the methylation call. This is useful for looking at methylation in specific contexts (e.g. `CpA` only), and also when using `GpC` methylases that introduce methylation in `GpC` context. The report looks like this:

Expand Down

0 comments on commit 37e2cad

Please sign in to comment.