Shiny App related to G4Hunter published in Bedrat et al. NAR 2016.
Supplementary Data can be downloaded from NCBI or Github.
- XVector
- shiny
1- download the project from github.
2- set the directory where you extract the project as your working directory in R by using the command setwd('PATH_TO_THE_PROJECT').
3- install the required packages by running the install-packages.r script.
4- in the R-console, type runApp().
5- a browser page should open with the app.
6- for the next time you want to run the app, you can just go your R-console and type shiny::runApp('PATH_TO_THE_PROJECT'). Thus if you have installed this app in a directory named work under your home directory, you should type shiny::runApp('~/work/G4HunterScore/').
Just type your sequence in the sequence field and you get the score as in the G4Hunter paper.
In parenthesis, the app also reports the length of the sequence you typed (or pasted).
Only C and G contribute to the score, every other letter (or character) have a score of 0.
Spaces are automaticaly removed.
Please cite "Bedrat A, Lacroix L, & Mergny JL (2016) Re-evaluation of G-quadruplex propensity with G4Hunter. Nucleic Acids Res 44(4):1746-1759.", when reporting results obtained with this App.