And I am a Computational Associate at the Broad Insititute.
- 🧬 Current Role: Exploring type 2 diabetes and cardiometabolic diseases with a focus on polygenic risk scores (PRS) and the integration of genetics with epigenetics.
- Worked as a Senior Data Analyst in the Sheynkman Lab.
- 🧬 Research :
- Developed a Python-based bioinformatics pipeline to analyze long-read RNA-Seq data and study protein isoforms impacted by splicing QTLs.
- Created tools to design UCSC browser tracks and visualize splicing effects on diseases like coronary artery disease.
- 📜 Publications:
- First-author: Biosurfer for systematic tracking of regulatory mechanisms leading to protein isoform diversity
bioRxiv preprint - Co-authored: Long-read proteogenomics to connect disease-associated sQTLs to the protein isoform effectors of disease
Published in American Journal of Human Genetics - Co-authored: Characterization of protein isoform diversity in human umbilical vein endothelial cells via long-read proteogenomics
Published in RNA Biology
- First-author: Biosurfer for systematic tracking of regulatory mechanisms leading to protein isoform diversity
- 📜 Completed my Master of Science in Computer Science.
- 🧬 Research: At the Shao Group, I developed pipelines for benchmarking and analyzing de novo metagenomic assemblies using PacBio IsoSeq (HiFi) datasets (GitHub).
- 🎓 As a Graduate Teaching Assistant, I facilitated learning for the "Introduction to System Programming" course.
📕 Interesting blogs.
- The complete sequence of a human genome
- New Discovery Shows Human Cells Can Write RNA Sequences Into DNA – Challenges Central Principle in Biology
- A cartoon guide to bioinformatics by a novice coder
- DeepMind’s protein-folding AI has solved a 50-year-old grand challenge of biology
- Ten simple rules for getting started with command-line bioinformatics