Adding the Vaccine Ontology (VO) with mappings

[yongqunh]

The Vaccine Ontology (VO) is a community-based biomedical ontology in the domain of vaccine and vaccination. VO systematically standardizes and integrates various vaccines, vaccine components, vaccine mechanisms, vaccine data types, leading to the enhanced computer-assisted reasoning. The VO represents various types of licensed vaccines or vaccines from clinical trials or research, vaccine ingredients, and vaccine responses. VO has been widely used in many different projects, such as the ImmPort project (https://www.immport.org/), Human Immunology Project Consortium (HIPC) project (https://immunespace.org/), and the Vaccine Adjuvant Compendium (VAC, https://vac.niaid.nih.gov/). The VO is also an Open Biomedical Ontologies (OBO) Foundry library ontology (https://obofoundry.org/ontology/vo).

Here we propose to add the VO with mappings as a non-standard OMOP vocabulary. We have mapped CVX, RxNorm and RxNorm extension terms to VO in an ontological manner. One advantage of the VO is that it includes solid semantic hierarchical structures and relations, thereby enhancing the integration and analysis of vaccine-related EHR data and so supporting public health.

This effort is led by the OHDSI vaccine vocabulary working group. The active members of working group who are working on this project include Dr. Jie Zheng, Laurel Li, Ellen Zhang, Penny Pan, and Dr. Yongqun “Oliver” He in the University of Michigan, and Dr. Qi Yang from IQVIA, and Dr. Alexander Davydov from Odysseus Data Services, Inc. We also look forward to collaborating more with the OHDSI vocabulary working group to further improve the work.

[yongqunh]

We have also submitted our filled Template 4 file for VO as a non-standard vocabulary. The file link is here: https://docs.google.com/spreadsheets/d/1JE-PXAAod4qUIUgrSgll7eaGn39hoCz6 (file title: VO-as-non-standard-vocab-template_4_6.26.2024.xlsx).