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tejalb edited this page Apr 11, 2016 · 3 revisions

Welcome to the cwf_denoise wiki!

This is a MATLAB package for denoising CTF -affected cryo-EM images based on the following manuscripts:

  1. Denoising and Covariance Estimation of Single Particle Cryo-EM Images by Tejal Bhamre, Teng Zhang, Amit Singer (http://arxiv.org/abs/1602.06632)

  2. Fast Steerable Principal Component Analysis by Zhizhen Zhao, Yoel Shkolnisky, Amit Singer (http://arxiv.org/abs/1412.0781)

This package should be used in conjunction with the cryo-EM tool box ASPIRE (http://spr.math.princeton.edu/) and will be included in the latest version of ASPIRE.

INSTRUCTIONS

  1. Download and install ASPIRE from http://spr.math.princeton.edu/ following the instructions for installation.
  2. Add ASPIRE files in your MATLAB path using initpath.m in ASPIRE.
  3. If this package is in a separate location than ASPIRE, add the package to your MATLAB path using cwf_paths.m
  4. Enjoy the example simulation scripts in cwf_scripts to denoise images.
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