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CloseCall: pipeline for processing RNA-RNA proximity data

CloseCall is a bioinformatics pipeline for identifying RNA-RNA interactions in NGS datasets generated using a new high-throughput protocol named Proximity RNA-seq to fix and sequence RNA complexes. The CloseCall pipeline has 3 main components:

  1. Mapping and QC
  2. Monte Carlo Simulation to identify statistically significant RNA-RNA interactions

The software is written in Perl and Java.

Documentation

The CloseCall documentation can be found with the code in the docs subfolder and can also read online.

Links

Credits

CloseCall was written by Steven Wingett, part of the Babraham Bioinformatics group.

License

GNU General Public License v3.0