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update the NEWS file to add in the Fabsgut variable change not previo…
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…usly provided in the NEWS file and provide better clarification
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Sarah Davidson-Fritz committed Feb 7, 2024
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Expand Up @@ -39,6 +39,10 @@ permeability chemicals and therefore predicts only three values
for calculating systemic bioavailability as ***Fbio = Fabs * Fgut * Fhep***
where first-pass hepatic metabolism was already available from
`calc_hep_bioavailability`.
* Changed the name of the variable describing fraction absorbed from the gut
prior to first-pass hepatic metabolism to ***Fabsgut*** to reflect that
***Fabs*** and ***Fgut*** are now modeled separately
(that is, ***Fabsgut = Fabs * Fgut***).
* Integrated ***Fabs*** and ***Fgut*** into oral exposure for all TK models and
integrated into population variability and uncertainty functions within
`invitro_uv`
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