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jchodera committed Dec 19, 2023
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<!doctype html><html lang=en-us><head><meta name=generator content="Hugo 0.120.4"><meta charset=utf-8><meta http-equiv=X-UA-Compatible content="IE=edge"><meta name=viewport content="width=device-width,initial-scale=1"><title>projects </title><meta name=description content="Developmental Research Project and Mentored Project Awards"><meta name=author content="newpixcom"><meta property="og:title" content="projects"><meta property="og:description" content="Developmental Research Project and Mentored Project Awards"><meta property="og:type" content="article"><meta property="og:url" content="https://asapdiscovery.org/awards/projects/"><meta property="article:section" content="awards"><div id=cookie-notice><span>We would like to use third party cookies and scripts to improve the
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merging design space required to achieve Aim 1, this project aims to digitise multi-step chemistry as required, by reaction pathways suggested my Manifold, for the synthesis of merging designs. Reaction protocols, CAR’s digitised reaction repertoire, will be generalised for automated chemistry suitability, as required by merging designs.
Aim 3: Mitigate synthetic attrition by executing multiple reaction routes per compound. Synthetic protocol
development requires exploration of multiple condition parameters and should not be limited to traditional bench- based investigations. This project aims to expand CAR’s ability to execute multiple protocols per reaction type, using the power of automation, to rapidly explore multiple reaction conditions. This extends to utilising multiple protocols for the synthesis of antivirals requiring chemistry, example Buchwald-Hartwig, sensitive to parameter choice.</p><h3 id=project-leader-warren-thompson-diamond-light-source-oxford-united-kingdom>Project Leader: Warren Thompson, Diamond Light Source, Oxford, United Kingdom
<a href=#project-leader-warren-thompson-diamond-light-source-oxford-united-kingdom><svg xmlns="http://www.w3.org/2000/svg" width="16" height="16" fill="currentcolor" class="bi bi-link" viewBox="0 0 16 16"><path d="M6.354 5.5H4a3 3 0 000 6h3a3 3 0 002.83-4H9c-.086.0-.17.01-.25.031A2 2 0 017 10.5H4a2 2 0 110-4h1.535c.218-.376.495-.714.82-1z"/><path d="M9 5.5a3 3 0 00-2.83 4h1.098A2 2 0 019 6.5h3a2 2 0 110 4h-1.535a4.02 4.02.0 01-.82 1H12a3 3 0 100-6H9z"/></svg></a></h3></ul></main><footer><footer id=footer><nav><ul><li><span>ASAP Discovery</span></li><li><a href=/concept>About Us</a></li><li><a href=/credits>Image Credits</a></li><li><a href=mailto:[email protected]>Contact Us</a></li></ul></nav></footer><link rel=stylesheet href=https://cdnjs.cloudflare.com/ajax/libs/KaTeX/0.7.1/katex.min.css integrity=sha384-wITovz90syo1dJWVh32uuETPVEtGigN07tkttEqPv+uR2SE/mbQcG7ATL28aI9H0 crossorigin=anonymous><script src=https://cdnjs.cloudflare.com/ajax/libs/KaTeX/0.7.1/katex.min.js integrity=sha384-/y1Nn9+QQAipbNQWU65krzJralCnuOasHncUFXGkdwntGeSvQicrYkiUBwsgUqc1 crossorigin=anonymous></script><script src=https://cdnjs.cloudflare.com/ajax/libs/KaTeX/0.7.1/contrib/auto-render.min.js integrity=sha384-dq1/gEHSxPZQ7DdrM82ID4YVol9BYyU7GbWlIwnwyPzotpoc57wDw/guX8EaYGPx crossorigin=anonymous></script><script>renderMathInElement(document.body,{delimiters:[{left:"$$",right:"$$",display:!0},{left:"$",right:"$",display:!1}]});for(var inlineMathArray=document.querySelectorAll("script[type='math/tex']"),inlineMath,tex,replaced,displayMath,i=0;i<inlineMathArray.length;i++)inlineMath=inlineMathArray[i],tex=inlineMath.innerText||inlineMath.textContent,replaced=document.createElement("span"),replaced.innerHTML=katex.renderToString(tex,{displayMode:!1}),inlineMath.parentNode.replaceChild(replaced,inlineMath);for(displayMathArray=document.querySelectorAll("script[type='math/tex; mode=display']"),i=0;i<displayMathArray.length;i++)displayMath=displayMathArray[i],tex=displayMath.innerHTML,replaced=document.createElement("span"),replaced.innerHTML=katex.renderToString(tex.replace(/%.*/g,""),{displayMode:!0}),displayMath.parentNode.replaceChild(replaced,displayMath)</script><script>renderMathInElement(document.body)</script></footer><script src=/js/kube.js type=text/javascript></script><script src=/js/kube.legenda.js type=text/javascript></script><script src=/js/master.js type=text/javascript></script></body></html>
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