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Merge pull request #220 from asapdiscovery/fix-#187
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Fix #187 : Update protocol link and description for SARS-CoV-2 Mpro biochemical assay protocol
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jchodera authored Sep 4, 2024
2 parents cf01df4 + a213e8d commit fea957a
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12 changes: 7 additions & 5 deletions data/outputs/assay_protocols.yaml
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permalink: http://asapdiscovery.org/outputs/assay-protocols/#MERS-CoV_Mpro_fluorescence-assay
name: MERS-CoV main protease (Mpro) activity fluorescence dose response biochemical assay
description: |
This is a functional, biochemical assay used to identify treatments for viral infectious disease in MERS 3C-like main viral protease.
Utilizing a direct enzyme activity measurement method, the experiment was performed in a 384-well plate reading the fluorescence intensity. This assay tested the mode of action of inhibition.
This biochemical assay measures the inhibition of protease activity of the MERS-CoV main viral protease (Mpro), also known as the 3C-like protease (3CLpro).
It is suitable for high-throughput dose-response measurements in a 384-well plates for supporting drug discovery efforts against this target.
links:
- name: assay protocol
url: https://www.protocols.io/view/mers-main-protease-mpro-fluorescence-dose-response-eq2ly7r1rlx9
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permalink: http://asapdiscovery.org/outputs/assay-protocols/#SARS-CoV-2_Mpro_fluorescence-assay
name: SARS-CoV-2 main protease (Mpro) activity fluorescence dose response biochemical assay
description: |
This is a functional, biochemical assay used to identify treatments for viral infectious disease that target SARS-CoV-2 3C-like main viral protease (MPro).
Utilizing a direct enzyme activity measurement method, the experiment was performed in a 384-well plate reading the fluorescence intensity. This assay tested the mode of action of inhibition.
This biochemical assay measures the inhibition of protease activity of the SARS-CoV-2 main viral protease (Mpro), also known as the 3C-like protease (3CLpro).
It is suitable for high-throughput dose-response measurements in a 384-well plates for supporting drug discovery efforts against this target.
links:
- name: assay protocol
url: https://www.protocols.io/view/sars-cov-2-main-protease-mpro-fluorescence-dose-re-81wgbye9nvpk
url: https://www.protocols.io/view/sars-cov-2-mpro-fluorescence-dose-response-81wgbye9nvpk
type: biochemical-assay-protocol
cores: [Biochemical Assay Core]
events:
- date: 2024-04-28
description: draft v4
- date: 2023-04-28
description: draft v3

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