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feat!: change CICERO fusion detection algorithm input parameters #206

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merged 5 commits into from
Nov 25, 2024

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jarbesfeld
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closes #205

  • Add checks for examining if the gene fusion event has biological meaning (using the sv_ort column) and if multiple gene symbols are listed for a fusion partner (one gene symbol is expected)
  • The documentation/associated metadata does not highlight any good ways to resolve this ambiguity, so for now I added code to skip fusion calls where this happens

@jarbesfeld jarbesfeld added enhancement New feature or request priority:medium Medium priority labels Nov 25, 2024
@jarbesfeld jarbesfeld requested a review from korikuzma November 25, 2024 15:27
@jarbesfeld jarbesfeld self-assigned this Nov 25, 2024
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@jarbesfeld jarbesfeld requested a review from korikuzma November 25, 2024 16:07
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@jarbesfeld jarbesfeld requested a review from korikuzma November 25, 2024 16:12
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@jarbesfeld jarbesfeld requested a review from korikuzma November 25, 2024 16:54
@jarbesfeld jarbesfeld merged commit 4013480 into main Nov 25, 2024
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@jarbesfeld jarbesfeld deleted the issue-205 branch November 25, 2024 17:02
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Reorganize/double-check CICERO translator
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