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pmcid: PMC11246037 | ||
image_filename: JIR-17-4483-g0003.jpg | ||
figure_link: /pmc/articles/PMC11246037/figure/f0002/ | ||
number: Figure 2 | ||
figure_title: '' | ||
caption: Differential expression genes in SICM by bioinformatics analysis. (A) Venn | ||
diagram of DEGs in 5 mice transcriptome datasets. The 12 co-DEGs in 5 datasets were | ||
marked in red. 36 co-DEGs were common differences expressed in 4 datasets. (B) The | ||
Volcano plot of 12 co-DEGs with red indicating high expression and blue indicating | ||
low expression. (C) The heatmap of 36 co-DEGs expression in 5 datasets. (D) GO enrichment | ||
analysis of 48 co-DEGs with enrichment score. (E) KEGG enrichment analysis of the | ||
48 co-DEGs with enrichment score. (F) PPI network of co-DEGs constructed in STRING | ||
databases with Cytoscape. 14 genes including S100A8 and S100A9 showed significant | ||
protein interactions. The size of the circle represents the significance. | ||
article_title: S100A9 as a Key Myocardial Injury Factor Interacting with ATP5 Exacerbates | ||
Mitochondrial Dysfunction and Oxidative Stress in Sepsis-Induced Cardiomyopathy. | ||
citation: Hui Pei, et al. J Inflamm Res. 2024;17:4483-4503. | ||
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doi: 10.2147/JIR.S457340 | ||
journal_title: Journal of Inflammation Research | ||
journal_nlm_ta: J Inflamm Res | ||
publisher_name: Dove | ||
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keywords: | ||
- S100A9 | ||
- SICM | ||
- bioinformatics analysis | ||
- mitochondrial dysfunction | ||
- ATP5 | ||
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pmcid: PMC11272554 | ||
image_filename: fphar-15-1370619-g001.jpg | ||
figure_link: /pmc/articles/PMC11272554/figure/F1/ | ||
number: FIGURE 1 | ||
figure_title: '' | ||
caption: Network pharmacology analysis of the neuroprotective effects of phenolic | ||
components in H. citrina leaves ((A) Venn diagram of phenolic components in H. citrina | ||
leaves and neuroprotective targets; (B) PPI network; (C) Network of “H. citrina | ||
leaves Phenolic Components - Common Targets – Neuroprotection”; (D) GO biological | ||
function enrichment; (E) KEGG pathway enrichment; (F) Network of “H. citrina leaves | ||
Phenolic Components - Common Targets - Pathways.” The component targets and disease | ||
targets information were searched through databases, and result graph were drew | ||
by Cytoscape software and Microbioinformatics Platform (https://www.bioinformatics.com.cn/)). | ||
article_title: Neuroprotective effects of total phenolics from Hemerocallis citrina | ||
Baroni leaves through the PI3K/AKT pathway. | ||
citation: Yanjun Jia, et al. Front Pharmacol. 2024;15:1370619. | ||
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doi: 10.3389/fphar.2024.1370619 | ||
journal_title: Frontiers in Pharmacology | ||
journal_nlm_ta: Front Pharmacol | ||
publisher_name: Frontiers Media S.A. | ||
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keywords: | ||
- Hemerocallis citrina Baroni leaves | ||
- total phenolics | ||
- network pharmacology | ||
- PI3K/AKT | ||
- neuroprotection | ||
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pmcid: PMC11272612 | ||
image_filename: fonc-14-1388016-g006.jpg | ||
figure_link: /pmc/articles/PMC11272612/figure/f6/ | ||
number: Figure 6 | ||
figure_title: '' | ||
caption: Interaction network, expression analysis, survival analysis, and stage-wise | ||
expression of ITGA3 and PKM in HCC. (A) Protein-protein interaction (PPI) network | ||
of differentially expressed genes (DEGs) identified in high-risk and low-risk groups. | ||
The network was constructed using the STRING database and visualized with Cytoscape | ||
software. (B) Comparison of ITGA3 expression levels between normal and tumor samples. | ||
(C) Comparison of PKM expression levels between normal and tumor samples. (D) Survival | ||
curves for patients with high and low PKM expression. (E) Survival curves for patients | ||
with high and low ITGA3 expression. (F) Comparison of PKM expression levels across | ||
different tumor stages. (G) Comparison of ITGA3 expression levels across different | ||
tumor stages. The symbols *** represent P-values of < 0.001. | ||
article_title: A novel basement membrane-related gene signature predicts prognosis | ||
and immunotherapy response in hepatocellular carcinoma. | ||
citation: Bingyao Li, et al. Front Oncol. 2024;14:1388016. | ||
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doi: 10.3389/fonc.2024.1388016 | ||
journal_title: Frontiers in Oncology | ||
journal_nlm_ta: Front Oncol | ||
publisher_name: Frontiers Media S.A. | ||
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keywords: | ||
- basement membrane | ||
- hepatocellular carcinoma | ||
- tumor microenvironment | ||
- prognosis | ||
- immunotherapy | ||
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pmcid: PMC11278150 | ||
image_filename: DDDT-18-3121-g0003.jpg | ||
figure_link: /pmc/articles/PMC11278150/figure/f0002/ | ||
number: Figure 2 | ||
figure_title: '' | ||
caption: PPI network of celastrol-HCC-ferroptosis genes. (A) Venn diagram illustrating | ||
the common targets of celastrol (Cel), hepatocellular carcinoma (HCC), and ferroptosis | ||
(FerrDb). FerrDb is the world’s first database that is dedicated to ferroptosis | ||
regulators and ferroptosis-disease associations. Here, “FerrDb” represents all genes | ||
associated with ferroptosis. (B) PPI network generated in Cytoscape 3.9.1 by importing | ||
the STRING data for 31 shared targets. (C) Core gene cluster filtered by MCODE plugin | ||
in Cytoscape 3.9.1. Blue and red rectangular nodes together represent 31 common | ||
targets. The red nodes are the selected core gene cluster. Nodes are marked as corresponding | ||
ranks and larger circles indicate more important roles in the network. | ||
article_title: Integrating Network Pharmacology with in vitro Experiments to Validate | ||
the Efficacy of Celastrol Against Hepatocellular Carcinoma Through Ferroptosis. | ||
citation: Banglan Cai, et al. Drug Des Devel Ther. 2024;18:3121-3141. | ||
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doi: 10.2147/DDDT.S450324 | ||
journal_title: Drug Design, Development and Therapy | ||
journal_nlm_ta: Drug Des Devel Ther | ||
publisher_name: Dove | ||
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keywords: | ||
- network pharmacology | ||
- celastrol | ||
- hepatocellular carcinoma | ||
- ferroptosis | ||
- reactive oxygen species | ||
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https://www.ncbi.nlm.nih.gov/pmc/?term=(network-OR-PPI+cytoscape)+AND+(2024/06/01[PUBDATE]+%3A+3000/01/01[PUBDATE])&report=imagesdocsum&dispmax=100 | ||
10 results | ||
https://www.ncbi.nlm.nih.gov/pmc/?term=(network-OR-PPI+cytoscape)+AND+(2024/07/01[PUBDATE]+%3A+3000/01/01[PUBDATE])&report=imagesdocsum&dispmax=100 | ||
4 results |
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terms: | ||
- network OR PPI | ||
- cytoscape | ||
last_run: 2024/07/01 | ||
last_run: 2024/08/01 | ||
date_range: ~ |