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AlexanderPico authored and github-actions[bot] committed Aug 1, 2024
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Binary file added figures/PMC11246037__JIR-17-4483-g0003.jpg
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32 changes: 32 additions & 0 deletions figures/PMC11246037__JIR-17-4483-g0003.yml
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---
pmcid: PMC11246037
image_filename: JIR-17-4483-g0003.jpg
figure_link: /pmc/articles/PMC11246037/figure/f0002/
number: Figure 2
figure_title: ''
caption: Differential expression genes in SICM by bioinformatics analysis. (A) Venn
diagram of DEGs in 5 mice transcriptome datasets. The 12 co-DEGs in 5 datasets were
marked in red. 36 co-DEGs were common differences expressed in 4 datasets. (B) The
Volcano plot of 12 co-DEGs with red indicating high expression and blue indicating
low expression. (C) The heatmap of 36 co-DEGs expression in 5 datasets. (D) GO enrichment
analysis of 48 co-DEGs with enrichment score. (E) KEGG enrichment analysis of the
48 co-DEGs with enrichment score. (F) PPI network of co-DEGs constructed in STRING
databases with Cytoscape. 14 genes including S100A8 and S100A9 showed significant
protein interactions. The size of the circle represents the significance.
article_title: S100A9 as a Key Myocardial Injury Factor Interacting with ATP5 Exacerbates
Mitochondrial Dysfunction and Oxidative Stress in Sepsis-Induced Cardiomyopathy.
citation: Hui Pei, et al. J Inflamm Res. 2024;17:4483-4503.

doi: 10.2147/JIR.S457340
journal_title: Journal of Inflammation Research
journal_nlm_ta: J Inflamm Res
publisher_name: Dove

keywords:
- S100A9
- SICM
- bioinformatics analysis
- mitochondrial dysfunction
- ATP5

---
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31 changes: 31 additions & 0 deletions figures/PMC11272554__fphar-15-1370619-g001.yml
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---
pmcid: PMC11272554
image_filename: fphar-15-1370619-g001.jpg
figure_link: /pmc/articles/PMC11272554/figure/F1/
number: FIGURE 1
figure_title: ''
caption: Network pharmacology analysis of the neuroprotective effects of phenolic
components in H. citrina leaves ((A) Venn diagram of phenolic components in H. citrina
leaves and neuroprotective targets; (B) PPI network; (C) Network of “H. citrina
leaves Phenolic Components - Common Targets – Neuroprotection”; (D) GO biological
function enrichment; (E) KEGG pathway enrichment; (F) Network of “H. citrina leaves
Phenolic Components - Common Targets - Pathways.” The component targets and disease
targets information were searched through databases, and result graph were drew
by Cytoscape software and Microbioinformatics Platform (https://www.bioinformatics.com.cn/)).
article_title: Neuroprotective effects of total phenolics from Hemerocallis citrina
Baroni leaves through the PI3K/AKT pathway.
citation: Yanjun Jia, et al. Front Pharmacol. 2024;15:1370619.

doi: 10.3389/fphar.2024.1370619
journal_title: Frontiers in Pharmacology
journal_nlm_ta: Front Pharmacol
publisher_name: Frontiers Media S.A.

keywords:
- Hemerocallis citrina Baroni leaves
- total phenolics
- network pharmacology
- PI3K/AKT
- neuroprotection

---
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33 changes: 33 additions & 0 deletions figures/PMC11272612__fonc-14-1388016-g006.yml
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---
pmcid: PMC11272612
image_filename: fonc-14-1388016-g006.jpg
figure_link: /pmc/articles/PMC11272612/figure/f6/
number: Figure 6
figure_title: ''
caption: Interaction network, expression analysis, survival analysis, and stage-wise
expression of ITGA3 and PKM in HCC. (A) Protein-protein interaction (PPI) network
of differentially expressed genes (DEGs) identified in high-risk and low-risk groups.
The network was constructed using the STRING database and visualized with Cytoscape
software. (B) Comparison of ITGA3 expression levels between normal and tumor samples.
(C) Comparison of PKM expression levels between normal and tumor samples. (D) Survival
curves for patients with high and low PKM expression. (E) Survival curves for patients
with high and low ITGA3 expression. (F) Comparison of PKM expression levels across
different tumor stages. (G) Comparison of ITGA3 expression levels across different
tumor stages. The symbols *** represent P-values of < 0.001.
article_title: A novel basement membrane-related gene signature predicts prognosis
and immunotherapy response in hepatocellular carcinoma.
citation: Bingyao Li, et al. Front Oncol. 2024;14:1388016.

doi: 10.3389/fonc.2024.1388016
journal_title: Frontiers in Oncology
journal_nlm_ta: Front Oncol
publisher_name: Frontiers Media S.A.

keywords:
- basement membrane
- hepatocellular carcinoma
- tumor microenvironment
- prognosis
- immunotherapy

---
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32 changes: 32 additions & 0 deletions figures/PMC11278150__DDDT-18-3121-g0003.yml
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---
pmcid: PMC11278150
image_filename: DDDT-18-3121-g0003.jpg
figure_link: /pmc/articles/PMC11278150/figure/f0002/
number: Figure 2
figure_title: ''
caption: PPI network of celastrol-HCC-ferroptosis genes. (A) Venn diagram illustrating
the common targets of celastrol (Cel), hepatocellular carcinoma (HCC), and ferroptosis
(FerrDb). FerrDb is the world’s first database that is dedicated to ferroptosis
regulators and ferroptosis-disease associations. Here, “FerrDb” represents all genes
associated with ferroptosis. (B) PPI network generated in Cytoscape 3.9.1 by importing
the STRING data for 31 shared targets. (C) Core gene cluster filtered by MCODE plugin
in Cytoscape 3.9.1. Blue and red rectangular nodes together represent 31 common
targets. The red nodes are the selected core gene cluster. Nodes are marked as corresponding
ranks and larger circles indicate more important roles in the network.
article_title: Integrating Network Pharmacology with in vitro Experiments to Validate
the Efficacy of Celastrol Against Hepatocellular Carcinoma Through Ferroptosis.
citation: Banglan Cai, et al. Drug Des Devel Ther. 2024;18:3121-3141.

doi: 10.2147/DDDT.S450324
journal_title: Drug Design, Development and Therapy
journal_nlm_ta: Drug Des Devel Ther
publisher_name: Dove

keywords:
- network pharmacology
- celastrol
- hepatocellular carcinoma
- ferroptosis
- reactive oxygen species

---
4 changes: 2 additions & 2 deletions figures/fetch.log
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https://www.ncbi.nlm.nih.gov/pmc/?term=(network-OR-PPI+cytoscape)+AND+(2024/06/01[PUBDATE]+%3A+3000/01/01[PUBDATE])&report=imagesdocsum&dispmax=100
10 results
https://www.ncbi.nlm.nih.gov/pmc/?term=(network-OR-PPI+cytoscape)+AND+(2024/07/01[PUBDATE]+%3A+3000/01/01[PUBDATE])&report=imagesdocsum&dispmax=100
4 results
2 changes: 1 addition & 1 deletion query_config.yml
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terms:
- network OR PPI
- cytoscape
last_run: 2024/07/01
last_run: 2024/08/01
date_range: ~

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