LocScale – reference-based density scaling for local sharpening of cryo-EM maps

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Locscale is a density scaling (sharpening) procedure that aims to enhance interpretability of cryo-EM density maps

LocScale is developed in the Sachse lab at EMBL by Arjen Jakobi.

[//]: # (##### LocRes - local resolution estimation based on windowed FSC calculation)

[//]: # (##### LocScale - local sharpening based on reference-based amplitude scaling)

[//]: # (LocFSC - local model validation based on FSC_ref calculations)

Please see the Wiki pages for dowload/usage instructions and tutorial.

For bug reports please use the [GitLab issue tracker](https://git.embl.de/jakobi/LocScale/issues).

For questions or comments please contact [email protected] or [email protected]