synthpop

Tools to answer questions about: optimal sequencing parameters in a large PacBio CCS sequencing project; comparative performance of existing SV discovery tools; benefits of joint SV discovery over a large population; limits of SV discovery and motivations for new joint tools.

Overview of the tools

Questions

Which read length and coverage to use for detecting SVs in a large population?

What are the advantages of joint calling?

Which SVs are difficult to find?