About/Citing

This is an interactive Shiny-based app that visualises the analysed data for CRISPR screens using the PbHiT system in the rodent malaria parasite Plasmodium berghei” as described in Jonsdottir et al. DOI: https://doi.org/10.1101/2024.04.20.590404

Generated by the Bushell lab at Umeå University. http://www.bushelllab.com/

License

MIT license

Files

• count.R -- takes all FASTQ files and outputs count matrices
• grstats.R -- takes count files and generates statistics
• crispr_methods_paper.R -- generates plots for the paper
• crispr_pools/* -- processed count files and metadata

These are related to the shiny app:

• global.R -- Load files into memory
• server.R -- Server backend
• start.R -- For starting the server
• Makefile -- For starting the server
• ui.R -- User interface declaration