neonatal antibiotics intervention model, based on neontal cpap intervention model #1587
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docs/source/models/intervention_models/neonatal/antibiotics_intervention.rst
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| - We assume that antibiotics availability captures actual use, and not simply the treatment being in the facility | ||
| - We assume that the delivery facility is the final facility in the care continum for deliveries that are transferred due to complications | ||
| - We assume that the relative risk of sepsis mortality with antibiotics in practice is a value that we can find in the literature |
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You could also add the limitation that currently we won't be modeling antibiotics effect on pneumonia mortality, which we have currently grouped with 'other causes'.
| @@ -45,9 +51,9 @@ This section describes how a CPAP intervention can be implemented and calibrated | |||
| Baseline Coverage Data | |||
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| 39.3% of CMONC facilities and 7.5% of BMONC facilities have CPAP, according to the 2016 Ethiopia EmONC Final Report. Please use these as a placeholder for now while we try to find reliable values for Nigeria and Pakistan. | |||
| 39.3% of CEmONC facilities and 7.5% of BEmONC facilities have CPAP, according to the 2016 Ethiopia EmONC Final Report. Please use these as a placeholder for now while we try to find reliable values for Nigeria and Pakistan. | |||
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| 39.3% of CEmONC facilities and 7.5% of BEmONC facilities have CPAP, according to the 2016 Ethiopia EmONC Final Report. Please use these as a placeholder for now while we try to find reliable values for Nigeria and Pakistan. | |
| 76.8% of CEmONC facilities and 30.2% of BEmONC facilities have antibiotics for neonatal sepsis, according to the 2016 Ethiopia EmONC Final Report. Please use these as a placeholder for now while we try to find reliable values for Nigeria and Pakistan. |
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| We will then use the conditional probabilities for simulants with and without access to determine which simulants die from sepsis. | ||
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| While we are searching the literature, we will use a placeholder relative risk of 0.50 (95% CI 0.25-0.75) of sepsis mortality for neonates with access to antibiotics. |
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This contradicts the placeholder of 0.72 in #1588
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I will make them match, but in a future PR, I would like to make it so that there is a single place for this in the docs.
docs/source/models/intervention_models/neonatal/antibiotics_intervention.rst
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| p(\text{sepsis}) | ||
| &= \sum_{\text{paths without antibiotics}} p(\text{path})\cdot p(\text{sepsis_wo})\\ | ||
| &+ \sum_{\text{paths with antibiotics}} p(\text{path})\cdot p(\text{sepsis_w})\\[.1in] | ||
| p(\text{sepsis_w}) &= \text{RR}_\text{antibiotics} \cdot p(\text{sepsis_wo}) |
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Once again, the \text{} commands (it renders on Read the Docs, but not on GitHub).
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Huh, TIL! I guess you need \_ (or on GitHub \\_ since the backslash also needs to be escaped).
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I'm going to switch to notation that uses conditional probabilities, I think it will be clearer as well as better typeset
…tervention.rst Co-authored-by: Alix Pletcher <[email protected]>
…tervention.rst Co-authored-by: Nathaniel Blair-Stahn <[email protected]>
…earch into neonatal_antibiotics
…earch into neonatal_antibiotics
This is very similar to #1585 , but for a different (cause, treatment) pair. I suspect I will have some edits to make to both of them when we go over them with the engineers tomorrow.